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Artykuły w czasopismach na temat „Cholesterol Physiological effect”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 1 lutego 2022

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1

Khudiar, Khalisa Kadim. "Effect of Magnetic Water on Some Physiological Aspects of Adult Male Rabbits." Iraqi Journal of Veterinary Medicine 36, no. 0E (April 4, 2012): 120–26. http://dx.doi.org/10.30539/iraqijvm.v36i0e.405.

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The present study was undertaken to search out thebeneficial effect of magnetized water on serumantioxidant, lipid profile and total protein of adult male rabbits. Twenty adult male rabbits were randomly divided into two equal groups and were treated daily for 60 days as follows:Group C:Rabbits of this group were allowed to ad libitumsupplyofdrinking water (control group),Group MG:Rabbits of this group were allowed to ad libitum supply of magnetic water.Fasting blood (for 8-12 hrs) samples were drawn by cardiac puncture technique at different times 0, 30 and 60 days of experiment for measuring

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Ngestiningsih, Dwi, Rejeki Andayani Rahayu, and Lusiana Batubara. "Effect of Superoxide Dismutase (SOD) Supplementation on Plasma Levels of Malondialdehyde (MDA), Total Cholesterol and LDL Cholesterol in the Elderly." Journal of Biomedicine and Translational Research 5, no. 2 (October 10, 2019): 29–33. http://dx.doi.org/10.14710/jbtr.v5i2.4679.

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Background: Several various physiological functions in elderly people are diminished due to cell or tissue damage. One of the probable causes are oxidative stress yielded by free radicals.Oxidative stress (ROS) induce lipid peroxidation in endothelial cell membrane, which generates atherosclerotic plaque. In a state of oxidative stress, MDA level will increased. The purpose of this study is to determine the effect of SOD supplementation on MDA, total cholesterol and LDL cholesterol plasma levels in the elderly.Methods: This study was open label, a randomized control trial. Subjects were elderl

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Freeman, Dilys J., Christopher J. Packard, James Shepherd, and Dairena Gaffney. "Polymorphisms in the Gene Coding for Cholesteryl Ester Transfer Protein are Related to Plasma High-Density Lipoprotein Cholesterol and Transfer Protein Activity." Clinical Science 79, no. 6 (December 1, 1990): 575–81. http://dx.doi.org/10.1042/cs0790575.

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1. Cholesteryl ester transfer protein activity may have a physiological effect on high-density lipoprotein levels. 2. We examined restriction fragment length polymorphisms associated with the cholesteryl ester transfer protein gene and the apolipoprotein AI gene in a group of 60 unrelated subjects selected from an initial survey of 5000 subjects on the basis of their high-density lipoprotein levels being high or low at the extremes of the distribution. The activities of cholesteryl ester transfer protein and lectithin:cholesterol acyltransferase (phosphatidylcholine-sterol acyltransferase, EC

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4

Ikram, Naila, Shehzada A. A. Babar, Tahir Aslam, Hira Malik, Natasha Zahid, and Anas Bin Tariq. "Physiological effect of cholecystectomy on lipid profile of patients with cholelithiasis." International Journal of Scientific Reports 6, no. 7 (June 23, 2020): 243. http://dx.doi.org/10.18203/issn.2454-2156.intjscirep20202638.

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<p class="abstract"><strong>Background:</strong> The association of cholecystectomy with alterations in lipid profile is well documented. Objectives of this study were to determine the effect of cholecystectomy on lipid profile of cholelithiasis patients.</p><p class="abstract"><strong>Methods:</strong> This cross-sectional observational study was done on 170 patients admitted in general surgery department of Naz Memorial Hospital, Karachi from July 2018 to June 2019. Symptomatic cholelithaisis patients between 18 to 60 years, elective cholecystectomy

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5

Domingues, Marco M., Bárbara Gomes, Axel Hollmann, and Nuno C. Santos. "25-Hydroxycholesterol Effect on Membrane Structure and Mechanical Properties." International Journal of Molecular Sciences 22, no. 5 (March 4, 2021): 2574. http://dx.doi.org/10.3390/ijms22052574.

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Cholesterol is responsible for the plasticity of plasma membranes and is involved in physiological and pathophysiological responses. Cholesterol homeostasis is regulated by oxysterols, such as 25-hydroxycholesterol. The presence of 25-hydroxycholesterol at the membrane level has been shown to interfere with several viruses’ entry into their target cells. We used atomic force microscopy to assess the effect of 25-hydroxycholesterol on different properties of supported lipid bilayers with controlled lipid compositions. In particular, we showed that 25-hydroxycholesterol inhibits the lipid-conden

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6

Reis, S. A., L. L. Conceição, D. D. Rosa, N. P. Siqueira, and M. C. G. Peluzio. "Mechanisms responsible for the hypocholesterolaemic effect of regular consumption of probiotics." Nutrition Research Reviews 30, no. 1 (December 20, 2016): 36–49. http://dx.doi.org/10.1017/s0954422416000226.

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AbstractCVD affect a large proportion of the world’s population, with dyslipidaemia as the major risk factor. The regular consumption of both probiotic bacteria and yeast has been associated with improvement in the serum lipid profile. Thus, the present review aims to describe and discuss the potential mechanisms responsible for the hypocholesterolaemic effect of regular consumption of probiotic bacteria and yeast. Regarding the hypocholesterolaemic effect of probiotic bacteria, the potential mechanisms responsible include: deconjugation of bile salts; modulation of lipid metabolism; and decre

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POST, Sabine M., Jaap TWISK, L. V. D. FITS, Elly C. M. DE WIT, Marco F. M. HOEKMAN, Willem H. MAGER та Hans M. G. PRINCEN. "Lipoprotein cholesterol uptake mediates up-regulation of bile-acid synthesis by increasing cholesterol 7α-hydroxylase but not sterol 27-hydroxylase gene expression in cultured rat hepatocytes". Biochemical Journal 341, № 2 (8 липня 1999): 339–46. http://dx.doi.org/10.1042/bj3410339.

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Lipoproteins may supply substrate for the formation of bile acids, and the amount of hepatic cholesterol can regulate bile-acid synthesis and increase cholesterol 7α-hydroxylase expression. However, the effect of lipoprotein cholesterol on sterol 27-hydroxylase expression and the role of different lipoproteins in regulating both enzymes are not well established. We studied the effect of different rabbit lipoproteins on cholesterol 7α-hydroxylase and sterol 27-hydroxylase in cultured rat hepatocytes. β-Migrating very-low-density lipoprotein (βVLDL) and intermediate-density lipoprotein (IDL) cau

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8

Seltman, H., W. Diven, M. Rizk, B. J. Noland, R. Chanderbhan, T. J. Scallen, G. Vahouny та A. Sanghvi. "Regulation of bile-acid synthesis. Role of sterol carrier protein2 in the biosynthesis of 7α-hydroxycholesterol". Biochemical Journal 230, № 1 (15 серпня 1985): 19–24. http://dx.doi.org/10.1042/bj2300019.

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Sterol carrier protein2 (SCP2) is known to stimulate utilization of cholesterol in enzymic reactions in which cholesterol is the substrate. Substantial recent experimental evidence indicates that SCP2: activates enzymic conversion of intermediates between lanosterol and cholesterol; stimulates the microsomal conversion of cholesterol into cholesterol ester in rat liver; and enhances mitochondrial utilization of cholesterol for pregnenolone formation in the adrenals. The conversion of cholesterol into 7 α-hydroxycholesterol is the rate-limiting step in bile-acid synthesis. We therefore investig

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9

LI, Feng, and Y. David HUI. "Synthesis and secretion of the pancreatic-type carboxyl ester lipase by human endothelial cells." Biochemical Journal 329, no. 3 (February 1, 1998): 675–79. http://dx.doi.org/10.1042/bj3290675.

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Human aortic extracts contain significant cholesteryl ester hydrolytic activity. The enzymic activity was shown to be activated by trihydroxylated bile salt, but not by dihydroxylated bile salt. Monospecific antibodies prepared against rat pancreatic carboxyl ester lipase (CEL, cholesterol esterase) immunoprecipitated cholesteryl ester hydrolytic activity from human aorta, demonstrating that the neutral CEL in aorta is highly similar to and probably identical with the pancreatic enzyme. Reverse transcriptase PCR amplification of mRNA from human aortic endothelial cells revealed de novo synthes

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10

Stoll, Peter, Andreas Gutzwiller, Martin Jost, Heiner Schneeberger, Robert Sieber, Hannes B. Staehelin, Christian Steffen, and Guenther Ritzel. "Short-term effect of whole milk and milk fermented by Pseudomonas fluorescens on plasma lipids in adult boars." British Journal of Nutrition 66, no. 1 (July 1991): 129–38. http://dx.doi.org/10.1079/bjn19910016.

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The short-term effects of whole milk and milk fermented by Pseudomonas fluorescens, of the amino acid composition of the diet and of feeding frequency on the level of plasma lipids, were investigated in six 1-year-old adult boars. The experimental diets contained equal amounts of protein, carbohydrates, fat and cholesterol. After an adaptation period of 5 d for each experimental treatment, blood was collected at regular intervals during 48 h and plasma levels of cholesterol, triacylglycerol, high-density-lipoprotein (HDL)-cholesterol and low-density-lipoprotein (LDL-cholesterol were examined).

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11

Shand, J. H., D. W. West, and D. J. Flint. "Effects of growth hormone on cholesterol metabolism in the lactating rat mammary gland." Journal of Endocrinology 152, no. 3 (March 1997): 447–54. http://dx.doi.org/10.1677/joe.0.1520447.

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Lactating rats were treated for 48 h with bromocriptine (to inhibit prolactin release) or bromocriptine together with an antiserum to rat GH. Animals given the combined treatment were also supplemented concurrently with bovine GH (bGH) or human insulin-like growth factor-I (hIGF-I). The effects of these treatments on the activities of 3-methyl-3-glutaryl-CoA reductase (HMG-CoA reductase), acyl-CoA:cholesterol acyltransferase (ACAT) and neutral cholesteryl ester hydrolase (CEH) and on the microsomal concentrations of non-esterified and esterified cholesterol were measured. Lack of prolactin dec

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12

Subbaiah, Papasani Venkata, Xian-Cheng Jiang, Natalia A. Belikova, Buzulagu Aizezi, Zhi Hua Huang, and Catherine A. Reardon. "Regulation of plasma cholesterol esterification by sphingomyelin: Effect of physiological variations of plasma sphingomyelin on lecithin-cholesterol acyltransferase activity." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1821, no. 6 (June 2012): 908–13. http://dx.doi.org/10.1016/j.bbalip.2012.02.007.

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Keating, Eleonora, Luna Rahman, James Francis, Anne Petersen, Fred Possmayer, Ruud Veldhuizen, and Nils O. Petersen. "Effect of Cholesterol on the Biophysical and Physiological Properties of a Clinical Pulmonary Surfactant." Biophysical Journal 93, no. 4 (August 2007): 1391–401. http://dx.doi.org/10.1529/biophysj.106.099762.

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14

Journal, Baghdad Science. "Effect of Hyper and Hypothyroidism on Lipid Profile and Liver Function of Male Rats." Baghdad Science Journal 8, no. 4 (December 4, 2011): 926–33. http://dx.doi.org/10.21123/bsj.8.4.926-933.

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This study was designed to investigate the effect of thyroid hormone disturbance on lipids profiles and liver functions. Eighteen mature male rats Rattus norvegicus were divided into three groups. The first and the second groups were injected subcutaneously with thyroxine (T4) and carbimazol (both at 600 µg/kg BW) respectively on alternate days, to produce recurrent periods of hyper and hypothyroidism .The control group which is the third group was injected with physiological saline. The process continued 4 weeks, after that, injection, blood specimens were collected to estimate serum levels o

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15

Azhmuldinov, E. A., Yu N. Chernyshenko, and M. G. Titov. "PHYSIOLOGICAL STATE AND PRODUCTIVITY OF ANIMALS UNDER THERMAL STRESS." VESTNIK OF THE BASHKIR STATE AGRARIAN UNIVERSITY 51, no. 3 (September 20, 2019): 26–31. http://dx.doi.org/10.31563/1684-7628-2019-51-3-26-31.

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A study was conducted of the effect of heat stress on the clinical and physiological state of male rabbits at the age of 5 months with an average live weight of 1551 g. The maximum temperature the animals were exposed to during the experiment was +42 °C. The study results showed a decrease in feed intake and an increase in water consumption, which contributed to a decrease in live weight. Hematological parameters, including hemoglobin, erythrocytes, leukocytes, total plasma protein, globulins and cholesterol increased during the action of this stress factor. It was found that the effect of hig

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16

Andersson, Kristina E., Tina Immerstrand, Karl Swärd, Björn Bergenståhl, Marie W. Lindholm, Rickard Öste, and Per Hellstrand. "Effects of oats on plasma cholesterol and lipoproteins in C57BL/6 mice are substrain specific." British Journal of Nutrition 103, no. 4 (October 20, 2009): 513–21. http://dx.doi.org/10.1017/s000711450999211x.

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Cholesterol-lowering effects of oats have been demonstrated in both animals and human subjects. However, the crucial properties of oat-containing diets that determine their health effects need to be further investigated to optimise their use. A mouse model would be a valuable tool, but few such studies have been published to date. We investigated the effects of oat bran on plasma cholesterol and lipoproteins in two substrains of C57BL/6 mice. Western diet was made atherogenic by the addition of 0·8 % cholesterol and 0·1 % cholic acid. After 4 weeks on atherogenic diet, total plasma cholesterol

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17

Ali, Alia Hussein. "Effects of Ethanolic Extract of Metracaria chamomela on Some Physiological Parameters in Male Rabbits." Iraqi Journal of Veterinary Medicine 39, no. 2 (December 24, 2015): 26–31. http://dx.doi.org/10.30539/iraqijvm.v39i2.173.

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The aim of this study is to explain the effect of Ethanolic extract 70% of Metracaria chamomella on some physiological parameters in male rabbits. Twelve adult male rabbits were used in this study and were divided equally into two groups: First group was control (C) and received normal saline for four weeks, the second group (Treated group) was intubated orally with ethanolic extract of Metracaria chamomella in a dose 70 mg/kg B.W. for four weeks. Blood samples were collected by heart puncture from each animal at the end of experiment. Blood sample was divided into a part for hematological stu

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18

Suzuki, Takuya, Shoko Yoshida, and Hiroshi Hara. "Physiological concentrations of short-chain fatty acids immediately suppress colonic epithelial permeability." British Journal of Nutrition 100, no. 2 (August 2008): 297–305. http://dx.doi.org/10.1017/s0007114508888733.

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Colonic fermentation products, SCFA, have various effects on colonic functions. Here, we found that physiological concentrations of SCFA immediately promote epithelial barrier function in the large intestine. Solutions of mixed and individual SCFA were applied to the caecal walls mounted on Ussing-type chambers. Transepithelial electrical resistance (TER) increased rapidly and reached a peak 35 % higher than that in the control specimen within 10 min post application of the SCFA mixture (80 acetate, 40 propionate, 20 butyrate (mmol/l)). The Lucifer yellow permeability, a paracellular transport

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19

Sushmitha K P, Vinod A N, and Nalini Ganesan. "Relationship between serum lipid profile and higher physiological level of bilirubin in cardiovascular patients." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (December 24, 2020): 7391–97. http://dx.doi.org/10.26452/ijrps.v11i4.3924.

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The present study is intended to investigate the protective role of high bilirubin concentration in patients with cardiovascular disease (CVD) and to analyse the relationship between serum bilirubin concentration and lipid profile in these patients. Cardiovascular diseases are the leading cause of death in the world, with early signs and symptoms starts many years earlier leading to myocardial infarction due to many cardiovascular risk factors like abnormal lipid profile. Serum bilirubin levels are determined both genetically and environmentally and vary through one's life. Under its anti-oxid

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Lukina, Anastasia A., Daniar V. Ismailov, Alexander P. Ilyin, Ksenia V. Derina, and Elena I. Korotkova. "Voltammetric Sensing System for the Detection of Cholesterol Based on the Ni-Bisurea-Pyrographite Composite." Key Engineering Materials 769 (April 2018): 250–55. http://dx.doi.org/10.4028/www.scientific.net/kem.769.250.

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Cholesterol plays a crucial role in the human body. High cholesterol level in blood is a marker of CVDs. Therefore, cholesterol determination techniques are necessary for clinical practice. Currently used cholesterol determination techniques involve enzymes or expensive and complicated equipment. Electrochemical techniques are widely spread in test-systems and sensors construction. Novel modification procedure for enzymeless cholesterol determination is suggested in this study. The electrochemical behavior of cholesterol on modified electrode was studied with the usage of cyclic and differenti

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Rubio, Ramón G., Eduardo Guzmán, Francisco Ortega, and Libero Liggieri. "Monolayers of Cholesterol and Cholesteryl Stearate at the Water/Vapor Interface: A Physico-Chemical Study of Components of the Meibum Layer." Colloids and Interfaces 5, no. 2 (May 20, 2021): 30. http://dx.doi.org/10.3390/colloids5020030.

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Langmuir monolayers containing different amounts of cholesterol and cholesteryl stearate were studied at two different temperatures (24 °C and 35 °C). The main goal was to contribute towards the understanding of how the variations in the chemical composition may affect the physico-chemical properties of these specific lipid monolayers. The model mixture was chosen considering that cholesteryl esters are present in cell membranes and some other biological systems, including human tear lipids. Therefore, an investigation into the effect of the lipid monolayer composition on their interfacial pro

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Bergelson, Bruce A., Tse-Kuan Yu, and Nicholas A. Ruocco. "Effects of Hypercholesterolaemia on Physiological Recruitment of Coronary Vascular Reserve in Swine." Clinical Science 90, no. 4 (April 1, 1996): 261–68. http://dx.doi.org/10.1042/cs0900261.

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1. The endothelium participates in the regulation of coronary vascular tone. As evidence exists from studies performed on epicardial vessels that hypercholesterolaemia impairs endothelial function, we tested the hypothesis that hypercholesterolaemia impairs coronary vascular reserve in an intact animal. 2. Domestic swine, maintained on a regular (n = 9) or a 2% high-cholesterol (n = 9) diet for 3 months were instrumented with a catheter in the left atrium for microsphere injection, a catheter in the anterior interventricular vein for venous sampling and an 82% stenosis in the left anterior des

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Shapira, Keren E., Marcelo Ehrlich та Yoav I. Henis. "Cholesterol depletion enhances TGF-β Smad signaling by increasing c-Jun expression through a PKR-dependent mechanism". Molecular Biology of the Cell 29, № 20 (жовтень 2018): 2494–507. http://dx.doi.org/10.1091/mbc.e18-03-0175.

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Transforming growth factor-β (TGF-β) plays critical roles in numerous physiological and pathological responses. Cholesterol, a major plasma membrane component, can have pronounced effects on signaling responses. Cells continually monitor cholesterol content and activate multilayered transcriptional and translational signaling programs, following perturbations to cholesterol homeostasis (e.g., statins, the commonly used cholesterol-reducing drugs). However, the cross-talk of such programs with ligand-induced signaling responses (e.g., TGF-β signaling) remained unknown. Here, we studied the effe

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Piccione, G., S. Casella, P. Pennisi, C. Giannetto, A. Costa, and G. Caola. "Monitoring of physiological and blood parameters during perinatal and neonatal period in calves." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 62, no. 1 (February 2010): 1–12. http://dx.doi.org/10.1590/s0102-09352010000100001.

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Rectal temperature, heart and respiratory rates, and the course of some blood parameters were monitored in calves during perinatal and neonatal periods. The study was carried out on eight Limousine calves. From all subjects, rectal temperature, heart rate, and respiratory rate were measured. Blood samples were taken at the same hour (9am) from the external jugular vein, and then centrifuged and stored until analyses. By means of an UV spectrophotometer, the following blood parameters were assessed for each subject: total protein, total cholesterol, triglycerides, glucose, non-esterified fatty

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Ara, Tanzin, Nasim Jahan, Nayma Sultana, Rama Choudhury, and Tahmina Yeasmin. "Effect of Ramadan Fasting on Total cholesterol (TC) Low density lipoprotein cholesterol (LDL-C) and High density lipoprotein cholesterol (HDL-C) in Healthy Adult Male." Journal of Bangladesh Society of Physiologist 10, no. 2 (March 31, 2016): 46–50. http://dx.doi.org/10.3329/jbsp.v10i2.27163.

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Background: Ramadan fasting has some effects on anthropometric, metabolic and physiological functions in the healthy subjects.Objective: To observe the effects of Ramadan fasting on serum total cholesterol (TC) low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol(HDL-C) in healthy adult male.Methods: This prospective observational study was carried out in the Department of Physiology, Sir Salimullah Medical College (SSMC), Dhaka between January and December 2013. Sixty healthy adult male aged 24 to 28 years were studied. Serum TC, LDL-C and HDL-C levels were est

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Mbemya, Gildas Tetaping, Marie Stéphanie Goka Chekem, Landry Lienou Lienou, Njina Nguedia Sylvain, Jiatsa Nathalie Donfack, Denise Damasceno Guerreiro, Jacques Romain Njimou, Ana Paula Ribeiro Rodrigues, and Phélix Bruno Telefo. "Eremomastax speciosa potentializes the PMSG-inducing effect on some physiological and biochemical parameters in PMSG-primed immature rats." Zygote 28, no. 6 (August 12, 2020): 482–88. http://dx.doi.org/10.1017/s0967199420000350.

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SummaryThe present study evaluated the effect of the aqueous extract from leaves of E. speciosa on some physiological and biochemical parameters of reproduction and the onset of puberty in pregnant mare serum gonadotropin (PMSG)-primed immature female rats. High pressure liquid chromatography (HPLC) was used to quantify the phenolic compounds in the methanol/methylene chloride (1:1) extract, the ethanolic and ethyl acetate fractions and the aqueous residue of E. speciosa. E. speciosa (0, 8, 32 or 64 mg/kg) were administered for 15 days to 24 non-PMSG-primed and 24 primed rats with 0.01 IU of P

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AL-Moramadhi, S. A. H. "The effect of aqueous extract of Marticaria Chamomilla flowers on some physiological properties in broiler chickens." Al-Qadisiyah Journal of Veterinary Medicine Sciences 10, no. 1 (June 30, 2011): 59. http://dx.doi.org/10.29079/vol10iss1art144.

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This study was conducted on broiler chickens to investigate the effect of Marticaria chamomilla flowers extract on some physiological properties. One day age Fawbro birds (Average weight 55g) were used in this study, they fed ad libtum until 7weeks age. (60 chickes) were divided into three groups (each group has 20 birds ).1-treatment one: administrated orally the aqueous extract of Marticaria chamomilla flowers at concentration 50mg /kg body weight .2-treatment two: administrated orally the aqueous extract of Marticaria chamomilla flowers at concentration 100mg /kg body weight3-control group:

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Attia, Y. A., A. A. Abdalah, H. S. Zeweil, F. Bovera, A. A. Tag El-Din, and M. A. Araft. "Effect of inorganic or organic selenium supplementation on productive performance, egg quality and some physiological traits of dual-purpose breeding hens." Czech Journal of Animal Science 55, No. 1 (January 25, 2010): 505–19. http://dx.doi.org/10.17221/1702-cjas.

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One hundred and twenty (100♀ + 20♂) 30-weeks-old dual-purpose breeding hens of Gimmizah strain were housed in individual cages in a semi-open house. Birds were distributed randomly into five treatments of 20♀ + 4♂. The 1st treatment was fed a control (unsupplemented) diet (17.5% CP and 11.4 MJ per kg diet) containing 0.10 mg Se/kg (low level). The 2nd, 3rd, 4th and 5th treatments were fed the control diet supplemented with 0.15 and 0.30 mg Se/kg from inorganic (sodium selenite) and organic (selenomethionine, as Se-yeast Selplex&reg; Alltech, Nicholasville, USA) sources, respectively. The t

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YA, Attia, Abdala AA, Zewei HS, F. Bover, El-Din AA Tag, and Araft MA. "Effect of inorganic or organic selenium supplementation on productive performance, egg quality and some physiological traits of dual-purpose breeding hens." Czech Journal of Animal Science 55, No. 11 (December 14, 2010): 505–19. http://dx.doi.org/10.17221/1715-cjas.

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One hundred and twenty (100♀ + 20♂) 30-weeks-old dual-purpose breeding hens of Gimmizah strain were housed in individual cages in a semi-open house. Birds were distributed randomly into five treatments of 20♀ + 4♂. The 1st treatment was fed a control (unsupplemented) diet (17.5% CP and 11.4 MJ per kg diet) containing 0.10 mg Se/kg (low level). The 2nd, 3rd, 4th and 5th treatments were fed the control diet supplemented with 0.15 and 0.30 mg Se/kg from inorganic (sodium selenite) and organic (selenomethionine, as Se-yeast Selplex&reg; Alltech, Nicholasville, USA) sources, respectively. The t

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Andersson, Jenny Marie, Carl Grey, Marcus Larsson, Tiago Mendes Ferreira, and Emma Sparr. "Effect of cholesterol on the molecular structure and transitions in a clinical-grade lung surfactant extract." Proceedings of the National Academy of Sciences 114, no. 18 (April 17, 2017): E3592—E3601. http://dx.doi.org/10.1073/pnas.1701239114.

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The lipid–protein film covering the interface of the lung alveolar in mammals is vital for proper lung function and its deficiency is related to a range of diseases. Here we present a molecular-level characterization of a clinical-grade porcine lung surfactant extract using a multitechnique approach consisting ofH1–C13solid-state nuclear magnetic spectroscopy, small- and wide-angle X-ray scattering, and mass spectrometry. The detailed characterization presented for reconstituted membranes of a lung extract demonstrates that the molecular structure of lung surfactant strongly depends on the con

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Neufeld, Karin J., Cindy L. Lederman, Patrick C. Choy, and Ricky Y. K. Man. "The effect of lidocaine on lysophosphatidylcholine-induced cardiac arrhythmias and cellular disturbances." Canadian Journal of Physiology and Pharmacology 63, no. 7 (July 1, 1985): 804–8. http://dx.doi.org/10.1139/y85-133.

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The production of arrhythmias in the isolated heart by perfusion with lysophosphatidylcholine has been well documented. However, the role of the lysophospholipid as a physiological factor in the generation of cardiac arrhythmias is not clear. In this study, a pharmacological approach was used to delineate the physiological significance of lysophosphatidylcholine during this cardiac dysfunction. Lidocaine (5–20 mg/L) was found to be effective in the protection of the isolated rat heart from the lysophospholipid-induced arrhythmias at pharmacological concentrations. The effect of lidocaine in th

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Drochioi, Ana Simona, Dan Cristian Moraru, Ilie Cristian Drochioi, Magdalena Iorga, Eduard Crauciuc, and Evelina Moraru. "The Effect of Antiviral Therapy on Lipid Metabolism in Patients with Viral Hepatitis C." Revista de Chimie 69, no. 8 (September 15, 2018): 2025–28. http://dx.doi.org/10.37358/rc.18.8.6466.

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The liver is the main metabolic organ, having complex physiological and biochemical roles, many of these functions being in a close relationship. It is also well known that hepatitis C virus infection is associated with changes in lipid metabolism. This is evident in liver dysfunctions, when liver functions are disturbed simultaneously. The aim of this study is to evaluate the effect of antiviral therapy on serum lipid level in patients with viral hepatitis C before and at the end of the 48 weeks of treatment compared patients treated with Interferon vs Interferon + Ribavirin and relation with

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Ikese, Chris Oche, Simon Terver Ubwa, Sunday Ogakwu Adoga, Stephen Inegedu Audu, and Michael Akor. "Evaluation of the effect of a modified proprietary poultry feed on cholesterol excretion in laying birds." Ovidius University Annals of Chemistry 30, no. 2 (January 1, 2019): 113–16. http://dx.doi.org/10.2478/auoc-2019-0020.

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Abstract The effect of modified proprietary poultry feed on cholesterol excretion in laying birds was evaluated. The study sort to lower the cholesterol content of eggs at the point of their physiological formation via a modification of the proprietary feed fed to laying poultry birds. This was with a view to lower the net cholesterol content in their eggs, thereby lowering the cholesterol levels available in such eggs for intake upon consumption. A 20% rice bran modification of the proprietary feed was made. Animal subjects were divided into experimental and control groups and the mean total

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Jacques, Hélène, Yves Deshaies, and Laurent Savoie. "Relationship between dietary tyrosine and plasma cholesterol in the rat." Canadian Journal of Physiology and Pharmacology 66, no. 8 (August 1, 1988): 1023–27. http://dx.doi.org/10.1139/y88-167.

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The present study was undertaken to measure the effects of dietary tyrosine added to fish protein and peanut meal on plasma cholesterol and plasma thyroid hormone levels in the rat. These dietary proteins were chosen because they contain similar amounts of tyrosine but release it at different rates during enzymatic hydrolysis. Casein was chosen as the reference protein. Supplementation was used to obtain tyrosine levels similar to that of casein. Male Sprague–Dawley rats were fed cholesterol-enriched diets containing 15% protein. After 3 weeks of experimental feeding, total postprandial plasma

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Simon, B. C., and R. A. Cohen. "EDTA influences reactivity of isolated aorta from hypercholesterolemic rabbits." American Journal of Physiology-Heart and Circulatory Physiology 262, no. 5 (May 1, 1992): H1606—H1610. http://dx.doi.org/10.1152/ajpheart.1992.262.5.h1606.

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The effects of the trace metal chelator, ethylenediaminetetraacetic acid (EDTA), on endothelium-dependent reactivity of isolated aorta from normal and hypercholesterolemic rabbits were studied. Rings of abdominal aorta were mounted in organ chambers for measurement of isometric force and incubated in physiological salt solution with or without EDTA (26 microM). Aortic rings were obtained from rabbits fed a standard diet or a diet enriched with 0.5% cholesterol and 4% peanut oil for 10 wk. In rabbits fed the standard diet, endothelium-dependent relaxations to acetylcholine and A23187 were not s

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Attia, Youssef Abd El-Wahab, Abd El-Hamid El-Syed Abd El-Hamid, Maria Cristina de Oliveira, Sameer Attiyah Nagadi, Kamel Ibrahim Kamel, El-Shohat Mohamed Qota, and Tarek Abd-Allah Sadaka. "Physiological parameters and productive performance of rabbit does and their offsprings with dietary supplementation of soy lecithin." Pesquisa Agropecuária Brasileira 53, no. 9 (September 2018): 1078–85. http://dx.doi.org/10.1590/s0100-204x2018000900012.

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Abstract: The objective of this work was to evaluate the effect of a dietary supplementation with soy lecithin (SL) on the productive performance and blood constituents of rabbit females and their offsprings. A total of 40 rabbits does were distributed into four treatments: control group, no dietary SL inclusion; and three groups with 0.5, 1.0, and 1.5% SL inclusion in the diets. The inclusion of 1.5% SL increased the count of blood cells and hemoglobin concentrations; 0.5-1.0% SL reduced the total cholesterol levels in the blood, as well as the low-density lipoprotein-cholesterol and the acti

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Sugiyanto, Raisatun Nisa, Rahmi Khamsita, and Ratna Asmah Susidarti. "Ethanolic Extract of Papaya (Carica papaya) Leaves Improves Blood Cholesterol Profiles and Bone Density in Ovariectomized Rats." Indonesian Journal of Cancer Chemoprevention 3, no. 3 (October 31, 2012): 426. http://dx.doi.org/10.14499/indonesianjcanchemoprev3iss3pp426-431.

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Bone loss and disturbance in the blood cholesterol profiles modulation are two effects caused by menopauses syndromes. As the estrogen concentration in the body decreased drastically, menopause women need the replacement of estrogen to keep the regulation of several physiological functions in the body, such as bone generation and cholesterol regulation in a good condition. Phytoestrogen in Carica papaya leaves, such as quercetin, could be one of the potential agents for the estrogenic effect. The aim of this study is to know the effects of papaya leaf extract (PLE) on the blood cholesterol pro

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Zhang, Bojun, Jay S. Naik, Nikki L. Jernigan, Benjimen R. Walker, and Thomas C. Resta. "Reduced membrane cholesterol after chronic hypoxia limits Orai1-mediated pulmonary endothelial Ca2+ entry." American Journal of Physiology-Heart and Circulatory Physiology 314, no. 2 (February 1, 2018): H359—H369. http://dx.doi.org/10.1152/ajpheart.00540.2017.

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Endothelial dysfunction in chronic hypoxia (CH)-induced pulmonary hypertension is characterized by reduced store-operated Ca2+ entry (SOCE) and diminished Ca2+-dependent production of endothelium-derived vasodilators. We recently reported that SOCE in pulmonary arterial endothelial cells (PAECs) is tightly regulated by membrane cholesterol and that decreased membrane cholesterol is responsible for impaired SOCE after CH. However, the ion channels involved in cholesterol-sensitive SOCE are unknown. We hypothesized that cholesterol facilitates SOCE in PAECs through the interaction of Orai1 and s

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Perales, Sonia, M. José Alejandre, Rogelio Palomino-Morales, Carolina Torres, Jose Iglesias, and Ana Linares. "Effect of Oxysterol-Induced Apoptosis of Vascular Smooth Muscle Cells on Experimental Hypercholesterolemia." Journal of Biomedicine and Biotechnology 2009 (2009): 1–8. http://dx.doi.org/10.1155/2009/456208.

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Smooth muscle cells (SMCs) undergo changes related to proliferation and apoptosis in the physiological remodeling of vessels and in diseases such as atherosclerosis and restenosis. Recent studies also have demonstrated the vascular cell proliferation and programmed cell death contribute to changes in vascular architecture in normal development and in disease. The present study was designed to investigate the apoptotic pathways induced by 25-hydroxycholesterol in SMCs cultures, using an in vivo/in vitro cell model in which SMCs were isolated and culture from chicken exposed to an atherogenic ch

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Polacek, Georgia N. L. Johnston, and Bill DeSola. "Effects of Glycemic Load and Exercise on Overweight/Obesity in College Students." Californian Journal of Health Promotion 4, no. 1 (March 1, 2006): 75–82. http://dx.doi.org/10.32398/cjhp.v4i1.735.

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We sought to assess the effect of glycemic load consumption and exercise in healthy college students. Participants (N=10) were screened on physiological measures then randomly assigned to experimental and control groups. Both groups participated in the walking program. Those in the experimental group were given the ADA diet exchange list modified to low glycemic load. At the end of 12 weeks, participants were reassessed. Members of the experimental group saw significant changes in total cholesterol and blood glucose. Changes in body mass index and waist circumference were not significant but s

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Wisker, Elisabeth, Thomas F. Schwejzer, Martina Daniel, and Walter Feldheim. "Fibre-mediated physiological effects of raw and processed carrots in humans." British Journal of Nutrition 72, no. 4 (October 1994): 579–99. http://dx.doi.org/10.1079/bjn19940061.

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Fibre-mediated physiological effects of raw and processed carrots were investigated in twenty-four young women under strict dietary control in two randomized crossover studies. For 3 weeks between 405 and 688 g of either raw frozen, blanched or canned carrots (first study), or raw or raw frozen carrots (second study) were consumed in addition to a low-fibre basal diet. Carrots provided 15 g dietary fibre (DF)/d. Total DF intake was 16.0 to 1.90 g (control periods) and 31 to 34 g (experimental periods). Faecal bulking effects of raw and processed carrots were similar (between 2.4 and 3.7 g addi

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Souza, L. A., M. M. Hunka, P. C. R. Nery, C. S. Coelho, H. E. C. C. C. Manso, and H. C. Manso Filho. "The effect of repeated barrel racing on blood biomarkers and physiological parameters in Quarter Horses." Comparative Exercise Physiology 14, no. 1 (February 23, 2018): 47–54. http://dx.doi.org/10.3920/cep170019.

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The objective of this study was to evaluate barrel horses undergoing a field test with one repetition. Quarter-Horses were used (14 males and females; average age: 6.5 years old), and they ran two times for 5 min in the same field. Six different periods were evaluated: rest (T-0), immediately after the first (T-1) and second races (T-2), and after 15 (T-15), 30 (T-30) and 240 min (T-240) of recovery. Heart rate (HR), speed, distance and duration were measured using a HR monitor with GPS during the races. Blood was collected to determinate glucose, lactate, total proteins (TP), albumin, globuli

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Lai, Chiou-lian, Chung-yao Hsu, Li-min Liou, Hsin-yi Hsieh, Yi-hsing Hsieh, and Ching-kuan Liu. "Effect of cholesterol and CYP46 polymorphism on cognitive event-related potentials." Psychophysiology 48, no. 11 (July 5, 2011): 1572–77. http://dx.doi.org/10.1111/j.1469-8986.2011.01221.x.

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Corrêa, Carline Barroso, Galileu Crovatto Veras, Giselle Paula Silva da Silva, Marcos Ferreira Brabo, and Evaldo Martins Silva. "Performance, body composition, and physiological response of tambaqui fed diet with green tea extract." Pesquisa Agropecuária Brasileira 53, no. 5 (May 2018): 540–46. http://dx.doi.org/10.1590/s0100-204x2018000500002.

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Abstract: The objective of this work was to evaluate the performance, body composition, and physiological state of tambaqui (Colossoma macropomum) fingerlings fed diets containing different levels of green tea (Camellia sinensis) extract (GTE). A completely randomized design was used with five treatments, different levels of GTE (0.00, 0.05, 0.30, 0.55, and 0.80 g kg-1) and three replicates. The diets were offered to fingerlings twice a day, for 90 days. The increase of dietary GTE levels promoted a positive quadratic effect on body lipids, hepatic lipids, retention of body lipids, glucose, an

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Levental, Ilya, Fitzroy J. Byfield, Pramit Chowdhury, Feng Gai, Tobias Baumgart, and Paul A. Janmey. "Cholesterol-dependent phase separation in cell-derived giant plasma-membrane vesicles." Biochemical Journal 424, no. 2 (November 11, 2009): 163–67. http://dx.doi.org/10.1042/bj20091283.

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Cell-derived GPMVs (giant plasma-membrane vesicles) enable investigation of lipid phase separation in a system with appropriate biological complexity under physiological conditions, and in the present study were used to investigate the cholesterol-dependence of domain formation and stability. The cholesterol level is directly related to the abundance of the liquid-ordered phase fraction, which is the majority phase in vesicles from untreated cells. Miscibility transition temperature depends on cholesterol and correlates strongly with the presence of detergent-insoluble membrane in cell lysates

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Wong, Hong Kin, Quok Cheong Choo, and Choy Hoong Chew. "Coconut milk gavage enhanced fecal bile excretion by modulating hepatic Fxr expression but failed to improve fasting serum cholesterol profile in C57BL/6 mice." OCL 27 (2020): 50. http://dx.doi.org/10.1051/ocl/2020037.

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The consumption of coconut milk has long been regarded as detrimental to cardiovascular health due to its high saturated fatty acid content. Contradictorily, emerging evidences have highlighted that the fatty acids in coconut lipids, which comprise mostly of medium-chain fatty acids (MCFA), may be beneficial to the regulation of serum cholesterol. To identify the potential health effect of coconut milk on lipid metabolism, this current study employed an intragastric gavage method on C57BL/6 mice to investigate the physiological and molecular alteration in the mice subject after 8 weeks of gava

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Martin, Gregory G., Barbara P. Atshaves, Kerstin K. Landrock, Danilo Landrock, Stephen M. Storey, Philip N. Howles, Ann B. Kier, and Friedhelm Schroeder. "Ablating L-FABP in SCP-2/SCP-x null mice impairs bile acid metabolism and biliary HDL-cholesterol secretion." American Journal of Physiology-Gastrointestinal and Liver Physiology 307, no. 11 (December 1, 2014): G1130—G1143. http://dx.doi.org/10.1152/ajpgi.00209.2014.

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On the basis of their abilities to bind bile acids and/or cholesterol, the physiological role(s) of liver fatty acid-binding protein (L-FABP) and sterol carrier protein (SCP) 2/SCP-x (SCP-2/SCP-x) gene products in biliary bile acid and cholesterol formation was examined in gene-ablated male mice. L-FABP (LKO) or L-FABP/SCP-2/SCP-x [triple-knockout (TKO)] ablation markedly decreased hepatic bile acid concentration, while SCP-2/SCP-x [double-knockout (DKO)] ablation alone had no effect. In contrast, LKO increased biliary bile acid, while DKO and TKO had no effect on biliary bile acid levels. LKO

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Lamonja-Vicente, Noemí, Rosalia Dacosta-Aguayo, Jorge López-Olóriz, Laia Prades-Senovilla, Francesca Roig-Coll, Alba Castells-Sánchez, Juan José Soriano-Raya та ін. "Sex-Specific Protective Effects of APOE ε2 on Cognitive Performance". Journals of Gerontology: Series A 76, № 1 (29 вересня 2020): 41–49. http://dx.doi.org/10.1093/gerona/glaa247.

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Abstract Apolipoprotein E (APOE) has an important role in the multiple trajectories of cognitive aging. However, environmental variables and other genes mediate the impact of APOE on cognition. Our main objective was to analyze the effect of APOE genotype on cognition and its interactions and relationships with sex, age, lipid profile, C-reactive protein, and Brain-derived neurotrophic factor (BDNF) genotype in a sample of 648 healthy participants over 50 years of age with a comprehensive neuropsychological assessment. Our results showed that APOE ε2 carriers performed better in the Verbal Mem

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Nataliia, PRYTULSKA, MOTUZKA Yuliia, and KOSHELNYK Anna. "PHYSIOLOGICAL EFFICIENCY OF DRINKS FROM FENUGREEK SEEDS." INTERNATIONAL SCIENTIFIC-PRACTICAL JOURNAL "COMMODITIES AND MARKETS" 39, no. 3 (September 20, 2021): 105–14. http://dx.doi.org/10.31617/tr.knute.2021(39)08.

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Background. Today, diabetes is one of the most common diseases with a steady upward trend. In particular in Ukraine it ranks 2nd among endocrine diseases in the number of patients. The annual growth of such patients averages 9.8–11 %. In the treatment of endocrine diseases, dietary nutrition aimed at normalizing metabolismis of great importance. It is recommended to add to the diet special, functionally-oriented foods based on biologically valuable raw materials. The aim of the workis to determine the physiological efficiency of drinks from fenugreek seeds. Materials and methods. The physiolo

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Casagrande, Stefania, Rianne Pinxten, Erika Zaid, and Marcel Eens. "Positive effect of dietary lutein and cholesterol on the undirected song activity of an opportunistic breeder." PeerJ 4 (October 6, 2016): e2512. http://dx.doi.org/10.7717/peerj.2512.

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Song is a sexually selected trait that is thought to be an honest signal of the health condition of an individual in many bird species. For species that breed opportunistically, the quantity of food may be a determinant of singing activity. However, it is not yet known whether the quality of food plays an important role in this respect. The aim of the present study was to experimentally investigate the role of two calorie-free nutrients (lutein and cholesterol) in determining the expression of a sexually selected behavior (song rate) and other behaviors (locomotor activity, self-maintenance ac

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