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1

Furuland, Hans. "Effects of Hemoglobin Normalization with Epoetin in Chronic Kidney Disease." Doctoral thesis, Uppsala University, Department of Medical Sciences, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5816.

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<p>Anemia is common in patients with chronic kidney disease (CDK), contributes to reduced Quality of Life (QoL) and is associated with cardiovascular disease, morbidity and mortality. Epoetin raises hemoglobin (Hb) and increases QoL and physical exercise capacity. Because of concerns about safety and economics, current anemia treatment with epoetin aims to achieve subnormal Hb (110-120 g/l). Normalization of Hb may be of additional benefit regarding QoL and cardiovascular effects. The present study examines the effects of Hb normalization with epoetin on safety variables, QoL, graft function a
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El, Hoss Sara. "Novel insights into the role of fetal hemoglobin in spleen function, red cell survival and ineffective erythropoiesis in sickle cell disease." Thesis, Université de Paris (2019-....), 2019. https://theses.md.univ-paris-diderot.fr/ELHOSS_Sara_va2_20190924.pdf.

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La drépanocytose est une maladie génétique héréditaire récessive causée par la substitution d'un acide aminé dans la chaîne β-globine aboutissant à la production d'hémoglobine anormale (HbS). Dans des conditions hypoxiques, l’HbS polymérise entraînant une falciformation et une perte de déformabilité des globules rouges (GR). Au cours de la drépanocytose, le dysfonctionnement splénique entraîne des complications potentiellement mortelles, en particulier chez les jeunes enfants. Généralement, une asplénie fonctionnelle précède la survenue d’une asplénie anatomique avec cependant une grande varia
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Duany, John. "Predicting Cognitive Workload with Measures from Functional Near-Infrared Spectroscopy (fNIRS) and Heart Rate." Honors in the Major Thesis, University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/942.

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The objective of this study was to assess low to high levels of Cognitive Workload by measuring heart rate and cortical blood flow in real-time. Four conditions were implemented into a within-subjects experimental design. Two conditions of difficulty and two conditions of trial order were used to illicit different levels of workload which will be analyzed with psychophysiological equipment. Functional Near-Infrared Spectroscopy (fNIRS) has become more prominent for measuring the blood oxygenation levels in the prefrontal cortex of individuals operating in hazardous work environments, students
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Colli, Celia. "Biodisponibilidade de ferro em dieta regional de São Paulo." Universidade de São Paulo, 1988. http://www.teses.usp.br/teses/disponiveis/9/9132/tde-03042008-162224/.

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Foi feito um estudo de determinação da biodisponibilidade de ferro em dieta regional de São Paulo, formulada com base no Estudo Nacional de Despesa Familiar (ENDEF). Para tanto, foram utilizados o método de repleção da hemoglobina em ratos anêmicos e o método \"in vitro\" de determinação de ferro dialisável. Paralelamente, avaliou-se as condições de obtenção de anemia em ratos. Concluiu-se que teores de 14 a 19 mg/g de ferro numa ração à base de caseína levam a uma redução de cerca de 40% (de 12,7g/dl para 7g/dl) da concentração de hemoglobina dos animais em períodos de 35 a 40 dias. A biodisp
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Sielenkämper, Andreas W. "Efficacy of diaspirin crosslinked hemoglobin (DCLHb) transfusion in O¦2 supply-dependent septic rats." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ32507.pdf.

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Kushnir, O. Yu. "Effect of melatonin on age-related changes of glycated hemoglobin content in the blood of alloxan diabetic rats." Thesis, БДМУ, 2022. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/19541.

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Martucci, Alexandre Fabrício. "Achados hemodinâmicos e de função e toxicidade renais após a infusão de carreadores de oxigênio baseados em hemoglobina." Botucatu, 2016. http://hdl.handle.net/11449/144382.

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Orientador: Yara Marcondes Machado Castiglia<br>Coorientador: Paulo do Nascimento Junior<br>Resumo: As reações adversas relacionadas à transfusão sanguínea chegam a 0,138%. Lesão Pulmonar Aguda Relacionada à Transfusão (TRALI), imunossupressão, febre, transmissão de patógenos e reação hemolítica aguda são as complicações mais comuns. Na tentativa de mitigar essas reações, pesquisadores tentam criar carreadores de oxigênio eficazes e não tóxicos. As soluções até agora apresentadas não foram melhores do que uma transfusão sanguínea. O óxido nítrico (NO) tem influência nas alterações vasculares e
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Ning, Jing 1953. "Effects of heterologous and homologous stroma-free hemoglobin and polyhemoglobin on complement activation, blood coagulation, platelet aggregation, and blood cells in rats." Thesis, McGill University, 1990. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74319.

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This research serves to answer the following basic question: Are potential toxic effects of hemoglobin solutions due to hemoglobin itself? Homologous and heterologous stroma-free hemoglobin and polyhemoglobin were investigated for their effects on complement activation, blood coagulation, platelet aggregation, blood cell counts, plasma electrolytes, proteins and enzymes in rats. A modified Mayer's method for testing whole complement hemolytic activity (CH$ sb{50}$) was developed. C$ sb3$ and C$ sb{ rm 3a}$ were also measured. Purified homologous or heterologous stroma-free hemoglobin or polyhe
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Miranda, Veronica Alcoforado de. "Análise da hemoglobina glicada na expressão de risco cardiovascular e renal em população acompanhada na atenção primária." Universidade do Estado do Rio de Janeiro, 2013. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=7913.

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Indivíduos com hemoglobina glicada (HbA1c) &#8805;6,5% e níveis normais de glicemia têm maior risco de complicações relacionadas ao diabetes, em médio e longo prazo. Estas evidências foram importantes na recomendação de que HbA1c &#8805;6,5% fosse aceita como critério diagnóstico de diabetes. Diferenças raciais/ étnicas tem sido encontradas quanto aos níveis de HbA1c. Níveis elevados de HbA1c em indivíduos sem diabetes e com níveis normais de glicemia em jejum tem sido associados a alterações micro e macrovasculares, entre elas alterações da filtração glomerular. Diversos marcadores inflamató
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Batina, Pierre. "Aspects metaboliques et toxicologiques de l'erythrocyte chez le rat traite aux nitrates et aux nitrites." Toulouse 3, 1988. http://www.theses.fr/1988TOU30196.

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11

Ebert, Natalie Rut. "Cortical spreading ischaemia als Folge von freiem Hämoglobin und erhöhter Kaliumkonzentration im Subarachnoidalraum induziert cortikale Infakte bei der Ratte." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2001. http://dx.doi.org/10.18452/14645.

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Die Pathogenese der verzögerten ischämischen Defizite (VIND) nach Subarachnoidalblutung wird mit Produkten der Hämolyse in Zusammenhang gebracht. Topische Hirnsuperfusion mit einer artifiziellen cerebrospinalen Flüssigkeit (ACSF), die L-NA, einen NOS-Inhibitor, in Kombination mit einer erhöhten Kaliumkonzentration erhielt, hat bei der Ratte zu Ischämien geführt. Dieses Phänomen wurde als Cortical spreading ischemia (CSI) bezeichnet. Dabei scheint es während der neuronalen Depolarisation zu einer gestörten Kopplung zwischen cerebralem Metabolismus und Blutfluß zu kommen, die zu einer Vasokonstr
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12

Vogel, Octavia L. "Marital Status as a Proxy Measure of Social Support and its Influence on Health Status and Depression Rates." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/iph_theses/49.

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Diabetes disproportionately affects minority populations. Social support, and more specifically marriage, has been found to buffer the negative effects of diabetes and depression. Data collected from African Americans with type 2 diabetes in Atlanta and NHANES data were compared to examine whether marriage affects health status and mental health. Approximately, 1742 African Americans aged 18-80 were included in this study. Chi square analysis revealed that married men had lower rates of depression (15.9% vs. 24.7%) compared to unmarried men (p < 0.05), but the same effect was not found in wome
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13

Guerci, Philippe. "Current and new therapies for the critically injured microcirculation The macro- and microcirculation of the kidney Endothelial dysfunction of the kidney in sepsis. Section 15: Infectious Diseases and Sepsis, Chapter 89 Impact of fluid resuscitation with hypertonic-hydroxyethyl starch versus lactated ringer on hemorheology and microcirculation in hemorrhagic shock Glycocalyx Degradation Is Independent of Vascular Barrier Permeability Increase in Nontraumatic Hemorrhagic Shock in Rats Glycocalyx shedding during stepwise hemodilution and microvascular permeability A LED-based phosphorimeter for measurement of microcirculatory oxygen pressure The role of bicarbonate precursors in balanced fluids during haemorrhagic shock with and without compromised liver function Effects of N-acetylcysteine (NAC) supplementation in resuscitation fluids on renal microcirculatory oxygenation, inflammation, and function in a rat model of endotoxemia Effect of Polyethylene-glycolated Carboxyhemoglobin on Renal Microcirculation in a Rat Model of Hemorrhagic Shock Resuscitation with PEGylated carboxyhemoglobin preserves renal cortical oxygenation and improves skeletal muscle microcirculatory flow during endotoxemia." Thesis, Université de Lorraine, 2020. http://www.theses.fr/2020LORR0053.

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Au cours des 20 dernières années, la microcirculation a été considérée comme la pierre angulaire du développement de la défaillance d’organe chez les patients critiques. De toute évidence, la microcirculation est devenue une cible thérapeutique. En raison de la complexité de la microarchitecture de ce système fonctionnel, variant d'un organe à l'autre, une thérapie ne peut pas «convenir pour tout». Les altérations observées dans la microcirculation sevèrement endommagée sont de 3 ordres: (i) le contenant défini par les différentes couches de la paroi vasculaire, y compris les cellules endothél
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Peixoto, Leonardo Gomes. "Análise do papel da metformina na via insulínica, não-insulínica e inflamatória." Universidade Federal de Uberlândia, 2015. https://repositorio.ufu.br/handle/123456789/15755.

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Fundação de Amparo a Pesquisa do Estado de Minas Gerais<br>Doutor em Genética e Bioquímica<br>CHAPTER II: Purpose: We performed a meta-analysis of randomized trials to assess the effect of metformin on inflammatory markers and metabolic parameters in subjects with diabetes. Methods: We performed comprehensive searches on NCBI, Cochrane, Science Direct databases from 1966 to Jun of 2015. We included randomized trials of at least 4 weeks duration that compared groups with diabetes before and after the treatment with metformin or metformin plus other drugs, and evaluated body mass index, blood gl
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15

Larion, Mioara Logan Timothy M. "Sensitivity of ST-EPR to the rate of motion at X and W-band." Diss., 2005. http://etd.lib.fsu.edu/theses/available/etd-11142005-112607.

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Thesis (M.S.)--Florida State University, 2005.<br>Advisor: Timothy Logan, Florida State University, College of Arts and Sciences, Dept. of Chemistry and Biochemistry. Title and description from dissertation home page (viewed Feb. 1, 2006). Document formatted into pages; contains viii, 37 pages. Includes bibliographical references.
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16

Hsu, Che-wei, and 許哲瑋. "Effects of expressing Vitreoscilla hemoglobin in Yarrowia lipolytica Po1g on enhancing its growth rate and lipid production." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/74474738133649040109.

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碩士<br>國立臺灣科技大學<br>化學工程系<br>101<br>Biodiesel has become an important alternative energy source. Recently, microbial oil from oleaginous microorganism is considered as a potential candidate for biodiesel production. Yarrowia lipolytica is a strictly aerobic oleaginous yeast. To solve the defects of hypoxic conditions, Vitreoscilla hemoglobin (VHb) has been used to enhance respiration and energy metabolism by promoting oxygen delivery. In this study, hp4d promoter was used for expressing VHb protein in Y. lipolytica. The effect of VHb protein on growth rate and lipid production of Y. lipolytica w
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Nolte, Heinrich Wilhelm. "Efficacy of Cellfood® and Switch™ as ergogenic aids in endurance athletes." Diss., 2002. http://hdl.handle.net/2263/28992.

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Please read the abstract in the section 00front of this document<br>Dissertation (MA (Human Movement Science))--University of Pretoria, 2006.<br>Biokinetics, Sport and Leisure Sciences<br>unrestricted
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Цибульська, Ангеліна Михайлівна. "Особливості фізіолого-біохімічних показників крові при злоякісних пухлинах різних органів". Магістерська робота, 2020. https://dspace.znu.edu.ua/jspui/handle/12345/4064.

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Цибульська А. М. Особливості фізіолого-біохімічних показників крові при злоякісних пухлинах різних органів : кваліфікаційна робота магістра спеціальності 091 «Біологія» / наук. керівник М. М. Малько. Запоріжжя : ЗНУ, 2020. 66 с.<br>UA : Кваліфікаційна робота виконана на 66 сторінках друкованого тексту, містить 12 таблиць та 8 рисунків. Перелік посилань включає 50 джерел, в тому числі, 10 англомовних видань. Об’єктом дослідження слугувала капілярна та венозна кров людей різного віку та статті. Мета роботи полягала у з’ясуванні особливостей гематологічних та біохімічних показників крові у люде
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Lee, Tsung-Peng, and 李宗朋. "Measurements of Hemoglobin Adducts in Blood Samples from Rats with N,N-dimethylformamide Exposure." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/02765714632113902712.

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碩士<br>長榮大學<br>職業安全與衛生研究所<br>94<br>Workers in synthetic leather manufacturing plants are exposed to N,N-dimethylformamide (DMF) by inhalation and skin contact. Biological samples are collected to conduct biological monitoring and assess workers’ exposure doses. In the metabolic process of human body, DMF can combine with glutathione to form N-methylcarbamoylglutathione (NMG). NMG and NMF can attach to the hemoglobin of red blood cells to form protein adducts, N-methylcarbamoylated valine-globin (NVH). It has been considered that the quantification of NVH in the hemoglobin of red blood cells
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Богдан, Анастасія Миколаївна. "Вплив водно-сольового екстракту з тіл Hirudo verbana на кількість лейкоцитів та еритроцитів у новонароджених щурів". Магістерська робота, 2020. https://dspace.znu.edu.ua/jspui/handle/12345/3993.

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Богдан А. М. Вплив водно-сольового екстракту з тіл Hirudo verbana на кількість лейкоцитів та еритроцитів у новонароджених щурів : кваліфікаційна робота магістра спеціальності 091 «Біологія» / наук. керівник О. К. Фролов. Запоріжжя : ЗНУ, 2020. 62 с.<br>UA : Дана робота викладена на 62 сторінках друкованого тексту, містить 11 таблиць та 7 рисунків. Список літератури включає 70 джерел. Об’єкт дослідження біологічні та терапевтичні ефекти від впливу дозованого водно-сольового екстракту отриманого з тканин Нirudo verbana. Метою роботи було вивчення загальної кількості еритроцитів та лейкоцитів
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Kotze, A., L. A. Carter, and Andy J. Scally. "Effect of a patient blood management programme on preoperative anaemia, transfusion rate, and outcome after primary hip or knee arthroplasty: a quality improvement cycle." 2012. http://hdl.handle.net/10454/6057.

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BACKGROUND: There are few data on the associations between anaemia, allogeneic blood transfusion (ABT), patient blood management, and outcome after arthroplasty in the UK. National agencies nevertheless instruct NHS Trusts to implement blood conservation measures including preoperative anaemia management. Internationally, blood management programmes show encouraging results. METHODS: We retrospectively audited 717 primary hip or knee arthroplasties in a UK general hospital and conducted regression analyses to identify outcome predictors. We used these data to modify previously published algori
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