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1

Samra Shahid, Afshan Noor, Amna Khalid, Ayesha Ellahi, Saleem Ahmed Khan, and Afnan Naeem. "Case fatality rate in patients of COVID-19 with anemia." Professional Medical Journal 29, no. 06 (2022): 785–90. http://dx.doi.org/10.29309/tpmj/2022.29.06.6650.

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Objective: To analyze SARS-CoV2 patients who presented to Military Hospital Rawalpindi having normal hemoglobin levels and those with low hemoglobin. Study Design: Cross Sectional study. Setting: Pathology Laboratory, Military Hospital Rawalpindi, Pakistan. Period: March 2020 to July 2020. Material & Methods: Patients of both genders and all age groups with positive PCR for Corona virus were included. Patients of both the genders and all age groups with negative PCR for corona virus. 2ml blood sample was taken in EDTA tubes from the patients in wards and Intensive care unit and Hemoglobin
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Feiner, John R., Heather E. Finlay-Morreale, Pearl Toy, et al. "High Oxygen Partial Pressure Decreases Anemia-induced Heart Rate Increase Equivalent to Transfusion." Anesthesiology 115, no. 3 (2011): 492–98. http://dx.doi.org/10.1097/aln.0b013e31822a22be.

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Background Anemia is associated with morbidity and mortality and frequently leads to transfusion of erythrocytes. The authors sought to directly compare the effect of high inspired oxygen fraction versus transfusion of erythrocytes on the anemia-induced increased heart rate (HR) in humans undergoing experimental acute isovolemic anemia. Methods The authors combined HR data from healthy subjects undergoing experimental isovolemic anemia in seven studies performed by the group. HR changes associated with breathing 100% oxygen by nonrebreathing facemask versus transfusion of erythrocytes at their
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Cahjono, Heru, Salmon Charles P. T. Siahaan, Ferdinand Aprianto Tannus, Rizki Perdani, and Eko Suhartono. "Erythrocyte Sedimentation Rate and Hemoglobin Levels in Pesticide Poisoning-Farmers." Jurnal Ilmiah Kedokteran Wijaya Kusuma 11, no. 2 (2022): 192. http://dx.doi.org/10.30742/jikw.v11i2.2441.

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Pesticides are chemicals used to control insects, fungi, weeds, and others. Unrestrained use of pesticides leads to poisoning that has an impact on inflammation and anemia. To provide evidence for this notion, acetylcholinesterase enzyme levels, blood sedimentation rates, and blood hemoglobin levels of farmers exposed to pesticides have been studied. The study design was quantitative in a cross-sectional manner. The participants of the study were all members of the Kurnia Makmur farmer group in Landasan Ulin Utara District, Banjarbaru with a total sample of 60 people. An examination of acetylc
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Kraus, D., J. Doeller, and C. Powell. "Sulfide may directly modify cytoplasmic hemoglobin deoxygenation in Solemya reidi gills." Journal of Experimental Biology 199, no. 6 (1996): 1343–52. http://dx.doi.org/10.1242/jeb.199.6.1343.

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The clam Solemya reidi, which survives in sulfide-rich sediments, houses intracellular sulfide-oxidizing bacteria as symbionts in its gills. The gill bacteriocytes also contain a high concentration of cytoplasmic hemoglobin. Although the in situ hemoglobin optical spectrum was not altered in the presence of hydrogen sulfide, hemoglobin deoxygenation was significantly slowed and incomplete when sulfide was present. A sulfide-mediated decrease in oxygen consumption rate, a shift in intracellular pH or the conversion of hemoglobin to an unusual derivative could all slow in situ hemoglobin deoxyge
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5

Tsai, Sheung-Pun, and J. Tze-Fei Wong. "Enhancement of Erythrocyte Sedimentation Rate by Polymerized Hemoglobin." Artificial Cells, Blood Substitutes, and Biotechnology 24, no. 5 (1996): 513–23. http://dx.doi.org/10.3109/10731199609117443.

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Ładyżyński, Piotr, Jan M. Wójcicki, Marianna I. Bąk, et al. "Hemoglobin Glycation Rate Constant in Non-diabetic Individuals." Annals of Biomedical Engineering 39, no. 11 (2011): 2721–34. http://dx.doi.org/10.1007/s10439-011-0366-6.

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Christman, Andrea L., Elizabeth Selvin, David J. Margolis, Gerald S. Lazarus, and Luis A. Garza. "Hemoglobin A1c Predicts Healing Rate in Diabetic Wounds." Journal of Investigative Dermatology 131, no. 10 (2011): 2121–27. http://dx.doi.org/10.1038/jid.2011.176.

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Newhall, Karina A., Kimon Bekelis, Bjoern D. Suckow, et al. "The relationship of regional hemoglobin A1c testing and amputation rate among patients with diabetes." Vascular 25, no. 2 (2016): 142–48. http://dx.doi.org/10.1177/1708538116650099.

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Objective The risk of leg amputation among patients with diabetes has declined over the past decade, while use of preventative measures—such as hemoglobin A1c monitoring—has increased. However, the relationship between hemoglobin A1c testing and amputation risk remains unclear. Methods We examined annual rates of hemoglobin A1c testing and major leg amputation among Medicare patients with diabetes from 2003 to 2012 across 306 hospital referral regions. We created linear regression models to study associations between hemoglobin A1c testing and lower extremity amputation. Results From 2003 to 2
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9

Raissa Rahmagia Zahran, Herri S. Sastramihardja, and Miranti Kania Dewi. "Hubungan Stadium Glomerular Filtration Rate (GFR) dengan Kadar Hemoglobin pada Pasien Penyakit Ginjal Kronis." Bandung Conference Series: Medical Science 5, no. 1 (2025): 627–34. https://doi.org/10.29313/bcsms.v5i1.16956.

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Abstract. Chronic kidney disease (CKD) is characterized by a decrease in glomerular filtration rate (GFR) <60 ml/min/1.73 that occurs for more than 3 months. Glomerular filtration rate is one of the parameters commonly used to assess kidney function and can describe the degree of kidney damage. Further deterioration of kidney function can lead to serious complications, including decreased hemoglobin levels that manifest clinically in symptoms of anemia. Changes in hemoglobin levels are one of the indicators that can be used to assess the occurrence of these complications. This study aims to
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10

Bunn, HF. "Subunit assembly of hemoglobin: an important determinant of hematologic phenotype." Blood 69, no. 1 (1987): 1–6. http://dx.doi.org/10.1182/blood.v69.1.1.1.

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Abstract Hemoglobin's physiologic properties depend on the orderly assembly of its subunits in erythropoietic cells. The biosynthesis of alpha- and beta-globin polypeptide chains is normally balanced. Heme rapidly binds to the globin subunit, either during translation or shortly thereafter. The formation of the alpha beta-dimer is facilitated by electrostatic attraction of a positively charged alpha-subunit to a negatively charged beta-subunit. The alpha beta-dimer dissociates extremely slowly. The difference between the rate of dissociation of alpha beta- and alpha gamma-dimers with increasin
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11

Bunn, HF. "Subunit assembly of hemoglobin: an important determinant of hematologic phenotype." Blood 69, no. 1 (1987): 1–6. http://dx.doi.org/10.1182/blood.v69.1.1.bloodjournal6911.

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Hemoglobin's physiologic properties depend on the orderly assembly of its subunits in erythropoietic cells. The biosynthesis of alpha- and beta-globin polypeptide chains is normally balanced. Heme rapidly binds to the globin subunit, either during translation or shortly thereafter. The formation of the alpha beta-dimer is facilitated by electrostatic attraction of a positively charged alpha-subunit to a negatively charged beta-subunit. The alpha beta-dimer dissociates extremely slowly. The difference between the rate of dissociation of alpha beta- and alpha gamma-dimers with increasing pH expl
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12

Suparningsih, Ni Made Dwi. "PERBEDAAN PENINGKATAN KADAR HEMOGLOBIN YANG MENGKONSUMSI TABLET FE DENGAN TABLET FE KOMBINASI VITAMIN C." JURNAL MEDIA KESEHATAN 7, no. 2 (2018): 192–97. http://dx.doi.org/10.33088/jmk.v7i2.245.

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According of Health Research Base (2013), prevalance of anemia in pregnancy (37,1%). The provision of iron tablets combination vitamin C increases of hemoglobin rate. Purpose of this study to known the difference in the enhancement of hemoglobin rate who consumed iron tablets with iron tablets combination vitamin C. This study used quasi experiment design. Samples in this study were 60. The measurement used hemoglobin digital. The analysis of data used dependent and independent test. Result of this study showed there was difference hemoglobin rate before and after treatments each the group wit
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Suparningsih, Ni Made Dwi. "PERBEDAAN PENINGKATAN KADAR HEMOGLOBIN YANG MENGKONSUMSI TABLET FE DENGAN TABLET FE KOMBINASI VITAMIN C." JURNAL MEDIA KESEHATAN 7, no. 2 (2018): 192–97. http://dx.doi.org/10.33088/jmk.v7i2.245.

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According of Health Research Base (2013), prevalance of anemia in pregnancy (37,1%). The provision of iron tablets combination vitamin C increases of hemoglobin rate. Purpose of this study to known the difference in the enhancement of hemoglobin rate who consumed iron tablets with iron tablets combination vitamin C. This study used quasi experiment design. Samples in this study were 60. The measurement used hemoglobin digital. The analysis of data used dependent and independent test. Result of this study showed there was difference hemoglobin rate before and after treatments each the group wit
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14

Phillips, H. M., B. M. Holland, J. G. Jones, A. L. Abdel-Moiz, T. L. Turner, and C. A. J. Wardrop. "Definitive Estimate of Rate of Hemoglobin Switching: Measurement of Percent Hemoglobin F in Neonatal Reticulocytes." Pediatric Research 23, no. 6 (1988): 595–97. http://dx.doi.org/10.1203/00006450-198806000-00013.

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Motterlini, R., R. Foresti, K. Vandegriff, M. Intaglietta, and R. M. Winslow. "Oxidative-stress response in vascular endothelial cells exposed to acellular hemoglobin solutions." American Journal of Physiology-Heart and Circulatory Physiology 269, no. 2 (1995): H648—H655. http://dx.doi.org/10.1152/ajpheart.1995.269.2.h648.

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We investigated the effect of different hemoglobins on the activation of endothelial heme oxygenase (HO), an inducible "stress" protein, which is responsible for heme catabolism, and we determined whether the propensity of hemoglobins to autoxidize correlates with endothelial heme uptake and cell injury. Porcine aortic endothelial cells were incubated for 6 h in the presence of 60 microM unmodified hemoglobin A0 (HbA0), hemoglobin cross-linked between the alpha-chains with bis-(3,5-dibromosalicyl)fumarate (alpha alpha Hb), or cyanomet-alpha alpha-hemoglobin (CNmet alpha alpha Hb). Endothelial
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16

Bhatti, Saeed Akram, Abdul Haseeb Khan, and Naeem Yaqoob. "GLYCATED HEMOGLOBIN (HbA1c)." Professional Medical Journal 22, no. 02 (2015): 208–14. http://dx.doi.org/10.29309/tpmj/2015.22.02.1376.

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HbA1c gives an integrated index of glycemia over the entire 120 days lifespan of red blood cells. Therefore, measuring HbA1c would be appropriate in diagnosing adisease characterized by chronic hyperglycemia and a gradual progression to complications.Objectives: our primary objective was to evaluate the use of HbA1c as screening test forundiagnosed diabetes (WHO criteria of Fasting plasma glucose (FPG) of ≥ 7mmol/l (126mg/dl))in healthy asymptomatic individuals in Pakistani population. Study Design and Methodology:A cross sectional population survey was carried on asymptomatic, healthy individ
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17

Eitan, Amnon, Hussein Sliman, Barak Zafrir, Keren Zissman, Moshe Y. Flugelman, and Ronen Jaffe. "Reduced Rate of Anemia after Transcatheter Aortic Valve Replacement." Journal of Clinical Medicine 13, no. 18 (2024): 5606. http://dx.doi.org/10.3390/jcm13185606.

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Background/Objectives: We sought to evaluate changes in hemoglobin level and renal function in patients 5–12 months after transcatheter aortic valve replacement (TAVR), and to examine possible relationships between these changes. Anemia is common in older people with severe aortic stenosis (AS). The two most common etiologies for anemia in this population are iron deficiency due to gastrointestinal blood loss and renal failure. Angiodysplasia in the gastrointestinal system is a feature of AS syndrome. Methods: We collected clinical data, including hemoglobin level and renal function before and
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18

Gilson, Stephen D., Brent B. Parker, and David C. Twedt. "Evaluation of two commercial test kits for detection of occult blood in feces of dogs." American Journal of Veterinary Research 51, no. 9 (1990): 1385–87. http://dx.doi.org/10.2460/ajvr.1990.51.09.1385.

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SUMMARY To evaluate the sensitivity and specificity of 2 commercial test kits for detection of occult blood in canine feces, various volumes of blood were administered to 6 dogs via orogastric tube. Blood volumes tested were chosen on the basis of hemoglobin quantities of 5, 10, 20, 200, 350, and 500 mg of hemoglobin/kg of body weight. Fecal specimens were collected twice daily and analyzed separately by 2 observers for the presence of occult blood by use of modified guaiac and orthotolodine tablet tests, and for melena by visual inspection. Five dogs given blood at the rate of 500 mg of hemog
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Vichinsky, Elliott, Deborah Hurst, Ann Earles, Klara Kleman, and Bertram Lubin. "Newborn Screening for Sickle Cell Disease: Effect on Mortality." Pediatrics 81, no. 6 (1988): 749–55. http://dx.doi.org/10.1542/peds.81.6.749.

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Newborn screening for sickle cell disease has been recommended as a method of decreasing patient mortality. However, its effectiveness in accomplishing this has not been reliably measured. To help determine the effectiveness, 10 years of experience in newborn screening have been summarized. The effects of early patient enrollment in a comprehensive treatment program on long-term morbidity and mortality are reported. From 1975 to 1985, 84,663 newborns were screened regardless of race or ethnic background. Bart's hemoglobin was present in 5%, hemoglobin AS in 2.6%, and hemoglobin AC in 0.75%. Ex
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Chalmers, A. H., and L. E. Snell. "Estimation of plasma and urinary hemoglobin by a rate spectrophotometric method." Clinical Chemistry 39, no. 8 (1993): 1679–82. http://dx.doi.org/10.1093/clinchem/39.8.1679.

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Abstract A method is described for estimating plasma and urinary hemoglobin concentrations as low as 3 mg/L. The assay measures at 528 nm the rate of peroxidation of chlorpromazine by hemoglobin and is not affected by ascorbate and bilirubin concentrations up to 500 mumol/L. Results by this method (mean +/- SD: 54.4 +/- 41.6 mg/L; n = 19) correlated well with those by a scanning spectrophotometric method (52.5 +/- 41.6 mg/L; r = 0.96) and a Coulter Instrument method (r = 0.99; Coulter method: 125 +/- 15 g/L; rate method: 122 +/- 15 g/L; n = 10, r = 0.99). The correlation for assays of 20 plasm
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Kinoshita, Maki. "Unexpectedly high rate of hemoglobin variants in the clinical laboratory: Effects on the levels of hemoglobin A1c." Tenri Medical Bulletin 23, no. 2 (2020): 88–95. http://dx.doi.org/10.12936/tenrikiyo.23-019.

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Samuel, RE, AE Guzman, and RW Briehl. "Hemoglobin S polymerization and gelation under shear II. The joint concentration and shear dependence of kinetics." Blood 82, no. 11 (1993): 3474–81. http://dx.doi.org/10.1182/blood.v82.11.3474.3474.

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Abstract The kinetics of hemoglobin S gelation are critical in sickle disease because microvascular obstruction can be avoided if red blood cells pass these vessels during the delay time, before polymerization and gelation occur in sufficient degree to rigidify the cells. Kinetics, including the delay time and the closely related exponential progress rate, are highly sensitive to hemoglobin concentration and degree of deoxygenation. Kinetics are also greatly accelerated by shear, an effect that may contribute to pathogenesis, since red blood cells deform and can undergo shear in vivo. Here we
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Samuel, RE, AE Guzman, and RW Briehl. "Hemoglobin S polymerization and gelation under shear II. The joint concentration and shear dependence of kinetics." Blood 82, no. 11 (1993): 3474–81. http://dx.doi.org/10.1182/blood.v82.11.3474.bloodjournal82113474.

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The kinetics of hemoglobin S gelation are critical in sickle disease because microvascular obstruction can be avoided if red blood cells pass these vessels during the delay time, before polymerization and gelation occur in sufficient degree to rigidify the cells. Kinetics, including the delay time and the closely related exponential progress rate, are highly sensitive to hemoglobin concentration and degree of deoxygenation. Kinetics are also greatly accelerated by shear, an effect that may contribute to pathogenesis, since red blood cells deform and can undergo shear in vivo. Here we examine t
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Tjepkema, John D., Robert E. Cashon, Jason Beckwith, and Christa R. Schwintzer. "Hemoglobin in Frankia, a Nitrogen-Fixing Actinomycete." Applied and Environmental Microbiology 68, no. 5 (2002): 2629–31. http://dx.doi.org/10.1128/aem.68.5.2629-2631.2002.

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ABSTRACT Frankia strain CcI3 grown in culture produced a hemoglobin which had optical absorption bands typical of a hemoglobin and a molecular mass of 14.1 kDa. Its equilibrium oxygen binding constant was 274 nM, the oxygen dissociation rate constant was 56 s−1, and the oxygen association rate constant was 206 μM−1 s−1.
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Diouf, Niokhor Ndane, O. Boye, M. N. Coly, et al. "Variation in Hemoglobin A1c Linked to Hemoglobin S: Comparison of Analysis Results from ion Exchange Chromatography and an Immunoturbidimetric Method." Asian Journal of Biochemistry, Genetics and Molecular Biology 15, no. 4 (2023): 1–7. http://dx.doi.org/10.9734/ajbgmb/2023/v15i4346.

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Hemoglobin S can interfere with the measurement of glycated hemoglobin, an essential tool for diagnosing and monitoring diabetes. The objective of this study is to evaluate the analytical performance of 2 glycated haemoglobin assay methods.
 A prospective cross-sectional study was conducted where 186 patients (61 homozygous sickle cell disease, 61 AA type subjects and 64 AS type subjects) were recruited. Glycated hemoglobin was measured by immunoturbidimetry method and ion exchange chromatography.
 The coefficient of variation (CV) of the repeatability is 2.34% and 1.13% (normal rate
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Silva, Daniele Pinheiro da, Bianca Prato Ribeiro, Ana Cláudia Scatolim de Almeida, and Danila Fernanda Rodrigues Frias. "Avaliação do Perfil Fisiológico e Hematológico de Equinos Submetidos a Provas de Três Tambores." Ensaios e Ciência C Biológicas Agrárias e da Saúde 27, no. 2 (2023): 204–8. http://dx.doi.org/10.17921/1415-6938.2023v27n2p204-208.

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A avaliação do desempenho dos equinos se torna fundamental para o reconhecimento de suas habilidades, além da intensidade do exercício mais adequada para diferentes fases de treinamento. A presente pesquisa teve por objetivo avaliar o perfil fisiológico e hematológico de equinos submetidos a provas de três tambores. Participaram da pesquisa 15 equinos atletas de provas de três tambores. Foram realizadas três colheitas de sangue, a primeira antes da realização da prova, a segunda imediatamente após um percurso, realizado sob galope e a terceira após 30 minutos do término da passada. Foram colhi
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Azarov, Ivan, Xiaojun He, Anne Jeffers, et al. "Rate of nitric oxide scavenging by hemoglobin bound to haptoglobin." Nitric Oxide 18, no. 4 (2008): 296–302. http://dx.doi.org/10.1016/j.niox.2008.02.006.

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Lemon, D. D., P. K. Nair, E. J. Boland, J. S. Olson, and J. D. Hellums. "Physiological factors affecting O2 transport by hemoglobin in an in vitro capillary system." Journal of Applied Physiology 62, no. 2 (1987): 798–806. http://dx.doi.org/10.1152/jappl.1987.62.2.798.

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O2 transport was examined by measuring the fractional saturation of concentrated hemoglobin solutions flowing through an artificial capillary that was approximately 27 micron in diameter and embedded in a silicone rubber film approximately 170 micron thick. The effects of pH, hemoglobin concentration, O2 tension, temperature, and organic phosphate were measured and analyzed quantitatively by a rigorous mathematical model that included the geometry of the capillary in the silicone film, parabolic flow velocity distributions inside the lumen, and cooperative O2 binding by hemoglobin. The rates o
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Rees, D. C., J. B. Clegg та D. J. Weatherall. "Is Hemoglobin Instability Important in the Interaction Between Hemoglobin E and β Thalassemia?" Blood 92, № 6 (1998): 2141–46. http://dx.doi.org/10.1182/blood.v92.6.2141.

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Abstract Hemoglobin E (HbE; 2β226glu-lys), globally the commonest hemoglobin variant, is synthesized at a slightly reduced rate and has a homozygous phenotype similar to heterozygous β thalassemia. Yet, when it is inherited together with a β thalassemia allele, the resulting condition, HbE/β thalassemia, is sometimes characterized by a severe, transfusion-dependent thalassemia major. The severity of this interaction has not been explained. We have explored the possibility that it may reflect the instability of HbE consequent upon globin chain imbalance imposed by the β thalassemia allele. Tim
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Rees, D. C., J. B. Clegg та D. J. Weatherall. "Is Hemoglobin Instability Important in the Interaction Between Hemoglobin E and β Thalassemia?" Blood 92, № 6 (1998): 2141–46. http://dx.doi.org/10.1182/blood.v92.6.2141.418k05_2141_2146.

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Hemoglobin E (HbE; 2β226glu-lys), globally the commonest hemoglobin variant, is synthesized at a slightly reduced rate and has a homozygous phenotype similar to heterozygous β thalassemia. Yet, when it is inherited together with a β thalassemia allele, the resulting condition, HbE/β thalassemia, is sometimes characterized by a severe, transfusion-dependent thalassemia major. The severity of this interaction has not been explained. We have explored the possibility that it may reflect the instability of HbE consequent upon globin chain imbalance imposed by the β thalassemia allele. Time-course
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Wang, Huaiming, and Zongqiang Jin. "CARDIOVASCULAR MONITORING IN THE TRAINING OF LONG-DISTANCE RUNNERS." Revista Brasileira de Medicina do Esporte 28, no. 6 (2022): 632–34. http://dx.doi.org/10.1590/1517-8692202228062022_0055.

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ABSTRACT Introduction Strengthening research on cardiac function risk assessment in running sports is beneficial to prevent sport-related cardiovascular injuries and sudden deaths in sports. Objective To study changes in cardiovascular response in athletes after long-distance running. Methods Changes in cardiovascular response indicators of long-distance runners before and after the five-kilometer race were monitored. Analyzed indices included heart rate, blood pressure, hemoglobin, and a cardiac function index. Results There were no statistically significant differences in heart rate, blood p
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Resta, Thomas C., Benjimen R. Walker, Mark R. Eichinger, and Michael P. Doyle. "Rate of NO scavenging alters effects of recombinant hemoglobin solutions on pulmonary vasoreactivity." Journal of Applied Physiology 93, no. 4 (2002): 1327–36. http://dx.doi.org/10.1152/japplphysiol.00175.2002.

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Many hemoglobin-based oxygen carriers (HBOCs) produce systemic and pulmonary hypertension and may increase microvascular permeability as a consequence of nitric oxide (NO) scavenging. In this study, we examined the effects of two recombinant human hemoglobin solutions, rHb1.1 and rHb2.0 for injection (rHb2.0), with different rates of NO scavenging on vasoconstrictor reactivity and vascular permeability in isolated, saline-perfused rat lungs. We hypothesized that rHb1.1, a first-generation HBOC with an NO scavenging rate similar to that of native human hemoglobin, would exacerbate pulmonary vas
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Tsoukias, Nikolaos M., and Aleksander S. Popel. "Erythrocyte consumption of nitric oxide in presence and absence of plasma-based hemoglobin." American Journal of Physiology-Heart and Circulatory Physiology 282, no. 6 (2002): H2265—H2277. http://dx.doi.org/10.1152/ajpheart.01080.2001.

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Experimental measurements have suggested a consumption rate of nitric oxide (NO) by red blood cells (RBCs) that is orders of magnitude smaller than that of an equivalent concentration of free hemoglobin in solution. This difference has been attributed to external diffusion limitations in the transport of NO from the plasma to the surface of the RBC or to resistance in the transport through the erythrocytic membrane. A detailed mathematical model is developed to quantify the resistance to NO transport around a single RBC and to predict the consumption rate in the presence and absence of extrace
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Wilkening, R. B., R. D. Molina, and G. Meschia. "Placental oxygen transport in sheep with different hemoglobin types." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 254, no. 4 (1988): R585—R589. http://dx.doi.org/10.1152/ajpregu.1988.254.4.r585.

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To study the effect of genetic differences in the maternal oxyhemoglobin dissociation curve on fetal O2 supply, we compared eight pregnant ewes homozygous for high O2 affinity hemoglobin (A) with eight pregnant ewes homozygous for low O2 affinity hemoglobin (B). Each ewe carried a single fetus. Fetal weights were not significantly different (A, 3,000 +/- 170 g; B, 3,070 +/- 270 g). The A ewes had significantly higher arterial O2 saturation (95 vs. 89.4%), uterine blood flow per kilogram of fetus (464 vs. 374 ml/min), uterine venous O2 saturation (78.1 vs. 67.5%), and placental-to-fetal weight
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AL-Fatlawi, Hawraa Yousif, and Dr Saher Mahmood Jwad. "Evaluation of Physiological and Immunological Parameters in Men with Type 2 Diabetic Nephropathy." NeuroQuantology 20, no. 5 (2022): 646–57. http://dx.doi.org/10.14704/nq.2022.20.5.nq22220.

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All men in the present research (15 healthy and 75 patients) have undergone clinical examination as well as other physiological and immunological tests, such as glycosylated hemoglobin test, hemoglobin level, platelets count, albumin to creatinine ratio (ACR), glomerular filtration rate (GFR), monocyte chemoattractant protein-1 (MCP-1 level), white blood cell count (WBC) and neutrophil to lymphocyte ratio (NLR). The results showed significant effect of (P<0.05) for the age groups and duration of diabetes mellitus on the hemoglobin level. However, there were no notable differences (P>0.05
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Alikiaii, Babak, Seyed Taghi Hashemi, and Mohammad Mokhtari. "Relationship Between Hemoglobin Level and the Expiration Date of Transfused Blood With the Death of Patients Admitted to the Intensive Care Unit." Jundishapur Journal of Medical Sciences 21, no. 4 (2022): 514–23. http://dx.doi.org/10.32598/jsmj.21.4.2519.

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Background and Objectives In this study, we aim to investigate the relationship of the numbers of days until blood expiration and pre-transfusion hemoglobin level with mortality rate in patients admitted to the intensive care unit (ICU) and received packed red blood cell (PRBC) transfusion. Subjects and Methods This is a retrospective cross-sectional study that was performed in 2020 on 205 patients admitted to the ICU of Al-Zahra Hospital in Isfahan, Iran in the past year and received PRBC transfusion. Their demographic information as well as information about related to the blood such as the
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Sakundech, Kanissarinn, and Worapol Aengwanich. "The Relationship of Clinicopathological Parameters and Formula for Predicting Malondialdehyde Level in Feline Immunodeficiency Virus (FIV) - infected Cats." Journal of the Hellenic Veterinary Medical Society 73, no. 2 (2022): 4119–24. http://dx.doi.org/10.12681/jhvms.26687.

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The objective of this study was to investigate clinicopathological parameters, malondialdehyde and total antioxidant power for analyzing correlation and predicting malondialdehyde in plasma of feline immunodeficiency virus (FIV)-infected cats. Body condition score (BCS), mucous membrane color score (MMCS), vital signs, hematological parameters, malondialdehyde and ferric reducing antioxidant power (FRAP) of 20 FIV-infected cats were examined. The correlation and multiple regression model were then analyzed. The results revealed the following. The correlation between hemoglobin vs. packed cell
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Tamussino, K. F., F. Gücer, O. Reich, F. Moser, E. Petru, and H. S. Scholz. "Pretreatment hemoglobin, platelet count, and prognosis in endometrial carcinoma." International Journal of Gynecologic Cancer 11, no. 3 (2001): 236–40. http://dx.doi.org/10.1136/ijgc-00009577-200105000-00013.

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We analyzed whether a low preteatment hemoglobin level is a prognostic factor in endometrial cancer and whether it is associated with thrombocytosis. Two hundred and twelve patients with endometrial cancer treated with surgery were reviewed. Data were analyzed with Pearson's chi-squared test, Fisher's exact test in contingency tables, the Mann–WhitneyU-test, the Student'st-test, and Kaplan-Meier estimates. Multivariate analysis was performed with the log-rank test and the Cox proportional hazard model. Thirty-nine patients (18%) had a pretreatment hemoglobin value of <12.0 g/dL. These 39 pa
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MAITA, Tetsuo. "The Rate of Molecular Evolution of Primate Hemoglobin is Becoming Slower." Primate Research 2, no. 1 (1986): 17–20. http://dx.doi.org/10.2354/psj.2.17.

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Cho, Namjun, Sunho Song, and Sanford A. Asher. "UV Resonance Raman and Excited-State Relaxation Rate Studies of Hemoglobin." Biochemistry 33, no. 19 (1994): 5932–41. http://dx.doi.org/10.1021/bi00185a034.

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Zindrou, D., K. M. Taylor, and J. P. Bagger. "Preoperative hemoglobin concentration and mortality rate after coronary artery bypass surgery." ACC Current Journal Review 11, no. 6 (2002): 83. http://dx.doi.org/10.1016/s1062-1458(02)00967-4.

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Faridz, Siska Monika, Syuhada Syuhada, and Akhmad Kheru. "KORELASI KADAR HEMOGLOBIN DENGAN LAJU FILTRASI GLOMERULUS PADA PASIEN GAGAL GINJAL KRONIK STADIUM 3 DAN 4." Jurnal Kebidanan Malahayati 7, no. 3 (2021): 489–94. http://dx.doi.org/10.33024/jkm.v7i3.4113.

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Background Chronic kidney disease was one of the 18 causes of death in 2010. Anemia is a complication of CKD that often occurs even earlier than other complications. Renal dysfunction results in reduced creatinine filtration ability and an increase in serum creatinine.Purpose of this study was to determine the correlation between hemoglobin levels and glomerular filtration rate in patients with stage 3 and 4 chronic kidney failure at Abdul Moeloek Hospital in Bandar Lampung in 2020.Methods This type of research is quantitative with retrospective analytical methods. The research was conducted a
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Zhou, Suiping, David Gell, Yi Kong, et al. "Mechanisms of Alpha Hemoglobin Stabilizing Protein (AHSP) Actions." Blood 104, no. 11 (2004): 499. http://dx.doi.org/10.1182/blood.v104.11.499.499.

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Abstract Alpha hemoglobin stabilizing protein (AHSP) is an abundant erythroid factor that specifically binds and stabilizes free α hemoglobin (Kihm et al., Nature 417:758, Gell et al., JBC, 277:40602). In mice, AHSP deficiency causes oxidative stress, mild anemia, and reticulocytosis. Furthermore, loss of AHSP exacerbates α globin precipitation and anemia in a murine model for β thalassemia. These data suggest that AHSP operates as a molecular chaperone to stabilize free α hemoglobin and inhibit its ability to catalyze redox chemistry. We investigated how AHSP associates with α hemoglobin and
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Mufliha, Ayu Laila, and Sri Dinengsih. "Effect of Date Juice and Coconut Water on Hemoglobin (Hb) Levels in Anemia Gravidarum." Jurnal Midpro 15, no. 1 (2023): 196–202. http://dx.doi.org/10.30736/md.v15i1.509.

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Anemia is something condition where amount cell blood red or hemoglobin concentration in it more low from usually. Deep anemia pregnancy is condition mother with hemoglobin levels (Hemoglobin) in blood more low from 11 gr/dl. Knowing influence giving juice dates (Phoenix dactylifera .L ) and coconut water (Coconut water) against mother's hemoglobin ( Hb ) level pregnant with anemia trimester III at the health center babelan. This study use Quasi experiment with pretest- posttest with control group design. Taking sample done use technique purposive sampling amounted to 34 mothers third trimeste
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Weiskopf, Richard B., John Feiner, Harriet W. Hopf, et al. "Oxygen Reverses Deficits of Cognitive Function and Memory and Increased Heart Rate Induced by Acute Severe Isovolemic Anemia." Anesthesiology 96, no. 4 (2002): 871–77. http://dx.doi.org/10.1097/00000542-200204000-00014.

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Background Erythrocytes are transfused to improve oxygen delivery and prevent or treat inadequate oxygenation of tissues. Acute isovolemic anemia subtly slows human data processing and degrades memory, increases heart rate, and decreases self-assessed energy level. Erythrocyte transfusion is efficacious in reversing these effects of acute anemia. We tested the hypothesis that increasing arterial oxygen pressure (Pao2) to 350 mmHg or greater would supply sufficient oxygen to be equivalent to augmenting hemoglobin concentration by 2-3 g/dl and thus reverse the effects of acute anemia. Methods Th
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Mairbäurl, Heimo, and Roy E. Weber. "Oxygen Transport by Hemoglobin." Comprehensive Physiology 2, no. 2 (2012): 1463–89. https://doi.org/10.1002/j.2040-4603.2012.tb00415.x.

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AbstractHemoglobin (Hb) constitutes a vital link between ambient O2 availability and aerobic metabolism by transporting oxygen (O2) from the respiratory surfaces of the lungs or gills to the O2‐consuming tissues. The amount of O2 available to tissues depends on the blood‐perfusion rate, as well as the arterio‐venous difference in blood O2 contents, which is determined by the respective loading and unloading O2 tensions and Hb‐O2‐affinity. Short‐term adjustments in tissue oxygen delivery in response to decreased O2 supply or increased O2 demand (under exercise, hypoxia at high altitude, cardiov
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M, Kusumawati, BM Wara Kushartanti, and Mochammad Noerhadi. "Hubungan antara pola konsumsi protein dan Fe dengan daya tahan jantung paru atlet sepakbola PS Semen Padang tahun 2003." Jurnal Gizi Klinik Indonesia 2, no. 1 (2005): 8. http://dx.doi.org/10.22146/ijcn.17346.

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Background: Low cardiorespiratory endurance will decrease the speed and skill in playing soccer. Good cardiorespiratory endurance is important factor in exercise and competition to reach the optimal achievement of the PS. Semen Padang soccer team players. Protein and Fe constitute a supporting factor in forming hemoglobin which is needed for increasing the cardiorespiratory endurance.Objective: This study was aimed at fi nding out the correlation between protein and Fe consumption patterns with the cardiorespiratory endurance of Semen Padang soccer team players in 2003.Methods: This was cross-
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Nascimento, Larissa Perez Pardo, Maria Paula de Oliveira Pires, Denise Miyuki Kusahara, Maria Angélica Sorgini Peterlini, and Mavilde da Luz Gonçalves Pedreira. "Post Hoc Analysis of Experimental Studies on Hemolysis Marker Levels in Red Blood Cells Infused through Manual and Electronic Flow Control Devices." Journal of the Association for Vascular Access 30, no. 2 (2025): 7–15. https://doi.org/10.2309/java-d-24-00029.

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Highlights RBC transfusions are common but carry patient risks. This study compares hemolysis in RBCs infused with manual and electronic devices. Electronic devices significantly reduced total hemoglobin levels post-infusion. Manual devices increased free hemoglobin and hemolysis, particularly at 10 mL/h. Abstract Aim: In this study, we aims to compare levels of hemolysis markers in red blood cells (RBCs) before and after infusion through manual and electronic flow control devices. Methods: A post hoc analysis was conducted on experimental studies involving 102 experimental situations with RBC
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Dzis, Ye I., O. Ya Tomashevska, I. Ye Dzis, and N. Ya Tomashevska. "Associations of glycated hemoglobin with hemoglobin levels and erythrocyte parameters." INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine) 21, no. 1 (2025): 57–65. https://doi.org/10.22141/2224-0721.21.1.2025.1492.

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Background. In patients with diabetes mellitus, pathologic changes occur in multiple organs and systems, the pathogenesis of which involves inflammatory reactions. The chronic inflammatory process can lead to the development of anemia. Several changes in red blood cells have been found to affect the processes of hemoglobin glycation, making it difficult to diagnose carbohydrate metabolism disorders. The aim of the present study was to analyze the relationship between the level of glycated hemoglobin (HbA1c) and the concentration of hemoglobin and erythrocyte parameters. Materials and methods.
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Lal, Rayhan A., David M. Maahs, Chrysoula Dosiou, Tandy Aye, and Marina Basina. "THE GUIDED TRANSFER OF CARE IMPROVES ADULT CLINIC SHOW RATE." Endocrine Practice 26, no. 5 (2020): 508–13. http://dx.doi.org/10.4158/ep-2019-0470.

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Objective: Every year, 500,000 youths in the U.S. with chronic disease turn 18 years of age and eventually require transfer to adult subspecialty care. Evidence-based interventions on the organization of transfer of care are limited, although engagement and retention in adult clinic are considered appropriate outcomes. Sustained continuity of care improves patient satisfaction and reduces hospitalization. Methods: We conducted a prospective, nonrandomized cohort study of patients with pediatric endocrine conditions, age 16 to 26 years, enrolled upon referral to the adult endocrine clinic of a
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