Gotowe bibliografie tematyczne / Including sustained release

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Gotowa bibliografia na temat „Including sustained release”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "Including sustained release"

Prajapat, Priyanka, Dilip Agrawal, and Gaurav Bhaduka. "A brief overview of sustained released drug delivery system." Journal of Applied Pharmaceutical Research 10, no. 3 (2022): 05–11. http://dx.doi.org/10.18231/j.joapr.2022.10.3.5.11.

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The most popular and patient-friendly method of drug administration is often thought to be the oral route of administration. Compared to conventional release formulations, advancements in formulation technology, including modified release dosage forms or sustained release oral dosage forms, have been extensively accepted. A sustained release dosage form provides a prolonged release of the drug over an extended period, thereby giving better patient compliance and enhanced bioavailability. Sustain release systems are considered a wiser approach for drugs with short half-lives requiring repeated

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Kalyani Shelar, Gauri Mahajan, Nikita Pagare, Prachiti Sahane, and Sakshi Bhosale. "Review on Sustained Release Tablet." International Journal of Scientific Research in Science and Technology 11, no. 6 (2024): 698–708. https://doi.org/10.32628/ijsrst241161126.

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This review highlights the advantages of SR formulations, including reduced side effects, enhanced drug utilization, improved treatment efficacy, and better patient compliance. Key considerations for developing sustained release tablet involve the drug's physicochemical properties and biological factors, such as absorption and metabolism. Various formulation strategies, including diffusion-controlled, dissolution-controlled, and osmotic systems, are discussed alongside essential evaluation parameters like density, hardness, and in-vitro drug release profiles. The outlook for sustained release

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Karim, Samira, Mohiuddin Ahmed Bhuiyan, and Md Sohel Rana. "Formulation and in vitro Evaluation of Glimepiride Sustained Release Tablets: Comparison with Immediate Release Tablets." Bangladesh Pharmaceutical Journal 18, no. 2 (2015): 157–62. http://dx.doi.org/10.3329/bpj.v18i2.24315.

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This work aims at the design of a sustained release formulation of glimepiride which is currently available in the treatment of type 2 diabetes mellitus and to investigate the effect of polymers on the release profile of glimepiride. Glimepiride sustained release tablets were prepared by direct compression method using different ratios of various release retarding polymers such as carbopol, ethyl cellulose, methocel K4 MCR, methocel K15 MCR, methocel K100 MCR and xanthum gum. These formulations were also compared with glimepiride immediate release tablets. The prepared tablets were subjected t

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Du, Guangsheng, and Xun Sun. "Current Advances in Sustained Release Microneedles." Pharmaceutical Fronts 02, no. 01 (2020): e11-e22. http://dx.doi.org/10.1055/s-0040-1701435.

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AbstractMicroneedles have been extensively investigated for intradermal delivery of drugs and vaccines due to advantages including high skin delivery efficiency, improved patient compliance, and potential for self-administration. However, traditional microneedles cannot regulate the release kinetics of payloads, limiting therapeutic utility of the biotherapeutics. Recently, several types of microneedles with sustained release properties, including slow-dissolving microneedles made of hydrophilic polymers, degradable microneedles made of hydrophobic polymers, and bioresponsive microneedles made

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Taghizadeh Davoudi, Ehsan, Mohamed Ibrahim Noordin, Ali Kadivar, Behnam Kamalidehghan, Abdoreza Soleimani Farjam, and Hamid Akbari Javar. "Preparation and Characterization of a Gastric Floating Dosage Form of Capecitabine." BioMed Research International 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/495319.

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Gastrointestinal disturbances, such as nausea and vomiting, are considered amongst the main adverse effects associated with oral anticancer drugs due to their fast release in the gastrointestinal tract (GIT). Sustained release formulations with proper release profiles can overcome some side effects of conventional formulations. The current study was designed to prepare sustained release tablets of Capecitabine, which is approved by the Food and Drug Administration (FDA) for the treatment of advanced breast cancer, using hydroxypropyl methylcellulose (HPMC), carbomer934P, sodium alginate, and s

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Rohan, Waghmare*1 Surekha Khamkar2. "Formulation and Evaluation of Sustained Release Metronidazole Tablet." International Journal of Scientific Research and Technology 2, no. 5 (2025): 355–63. https://doi.org/10.5281/zenodo.15421602.

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Metronidazole, an antibiotic commonly used to treat infections caused by anaerobic bacteria and certain protozoa, has a broad spectrum of activity. However, its frequent dosing regimen due to its short half-life often leads to poor patient compliance and fluctuations in plasma drug concentrations. The development of sustained-release formulations of metronidazole aims to improve its therapeutic effectiveness, enhance patient adherence, and minimize side effects.This study focuses on the formulation and evaluation of sustained-release (SR) tablets of metronidazole. The SR formulation was design

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Xiang, Aishuang, and Anthony J. McHugh. "Quantifying sustained release kinetics from a polymer matrix including burst effects." Journal of Membrane Science 371, no. 1-2 (2011): 211–18. http://dx.doi.org/10.1016/j.memsci.2011.01.050.

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Ujjwal, Kukreti, Nainwal Nidhi, Ale Yogita, et al. "Release Kinetic of Sustained Release Matrix Tablet of Linezolid Containing Polymer Blend." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 03 (2024): 1479–84. http://dx.doi.org/10.25258/ijpqa.15.3.60.

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Tuberculosis (TB) is a bacterial infection mainly affecting the lungs. TB is a major health problem worldwide and the occurrence of extensively drug-resistant TB (XDR-TB) and multidrug-resistant TB (MDR-TB) offers considerable hurdles to effective treatment and disease management. The growth of treatment-resistant Mycobacterium TB strains has prompted the investigation of alternate therapeutic techniques, including the application of sustained drug delivery. Sustained-release drugs reduce the need for frequent dosing can extend the effects of linezolid by 8 to 12 hours, thus improving the pati

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Thanh, Duyen Nguyen Thi, Duc Hoang Van, Minh Vo Xuan, Xuan Dam Thanh Thanh, and Tung Bui Thanh. "Design and Optimization of Hydrophilic Matrix-based Sustained Release Felodipine Tablets." International Journal of Pharmaceutical Sciences and Nanotechnology 11, no. 3 (2018): 4136–44. http://dx.doi.org/10.37285/ijpsn.2018.11.3.8.

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Felodipine is a calcium channel blocker used for hypertensive and unstable angina treatments. The sustained release formulations of felodipine have advantages of achieving good therapeutic effects, increasing the bioavailability, decreasing dosing times per day and reducing side effects.The aim of our study was to study the formulation screening, then use an experiment design for formulating a hydrophilic matrix sustained release tablet of felodipine. Methods: The optimization process had the influences of the chosen excipients (including HPMC E4M, HPMC E15LV) on the drug release. Three depend

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Guan, Ya, Hong Niu, Zhongting Liu, et al. "Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation." Science Advances 7, no. 35 (2021): eabj0153. http://dx.doi.org/10.1126/sciadv.abj0153.

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Nonhealing diabetic wounds are common complications for diabetic patients. Because chronic hypoxia prominently delays wound healing, sustained oxygenation to alleviate hypoxia is hypothesized to promote diabetic wound healing. However, sustained oxygenation cannot be achieved by current clinical approaches, including hyperbaric oxygen therapy. Here, we present a sustained oxygenation system consisting of oxygen-release microspheres and a reactive oxygen species (ROS)–scavenging hydrogel. The hydrogel captures the naturally elevated ROS in diabetic wounds, which may be further elevated by the o

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Książki na temat "Including sustained release"

Ó Dochartaigh, Niall. Deniable Contact. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780192894762.001.0001.

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Despite the importance of secret negotiations during the Northern Ireland conflict there is no full-length study of the use of back-channels in repeated efforts to end the ‘Troubles’. This book provides a textured account that extends our understanding of the distinctive dynamics of negotiations conducted in secret and the conditions conducive to the negotiated settlement of conflict. It disrupts and challenges some conventional notions about the conflict in Northern Ireland, offering a fresh analysis of the political dynamics and the intra-party struggles that sustained violent conflict and p

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Części książek na temat "Including sustained release"

Tournilhac, Olivier, and Peter Dreger. "Chronic Lymphocytic Leukaemia." In The EBMT/EHA CAR-T Cell Handbook. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94353-0_14.

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AbstractAlthough chronic lymphocytic leukaemia (CLL) was one of the first two entities in which CAR-T cells were evaluated, it has not yet arrived in the clinical routine. Since the landmark study by Porter et al. (2011), only six CLL-specific clinical trials have been published, altogether comprising no more than 155 patients (Porter et al. 2015; Gill et al. 2018; Turtle et al. 2017; Gauthier et al. 2020; Siddiqi et al. 2020; Wierda et al. 2020; Frey et al. 2020). All six of these studies investigated CD19-directed CAR-T constructs in heavily pretreated patients, mostly having failed BTKi+/−

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Luba, Rachel R., Sandra D. Comer, and Edward V. Nunes. "Abuse-Deterrent and Sustained-Release Opioid Formulations." In The Oxford Handbook of Opioids and Opioid Use Disorder. Oxford University Press, 2023. http://dx.doi.org/10.1093/oxfordhb/9780197618431.013.17.

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Abstract Abuse-deterrent formulations (ADF) of opioids were developed to mitigate opioid misuse and abuse in the context of pain management and medication treatment for opioid use disorder (MOUD). This chapter begins with a case study to illustrate the potential value of ADF formulations before outlining the historical context and rationale for developing ADF opioid medications and the principles of these formulations, including their pharmacokinetic and pharmacodynamic properties. It then reviews the laboratory studies of tamper resistance and discusses the subjective effects of these product

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Kapadia, Alok, and Atish S. Mundada. "Controlled-Release Injectables." In Novel Drug Delivery Systems (Part 2). BENTHAM SCIENCE PUBLISHERS, 2024. https://doi.org/10.2174/9789815313567124010009.

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The importance of controlled-release injections in drug delivery, including the recent technological developments in injectable emulsions, liposomes, and nanosuspensions for parenteral drug delivery, is discussed in four major sections in the current chapter. The 1st section delves into the application of these systems for poorly soluble drugs, proteins/peptides, vaccines, and gene therapeutics, highlighting their potential to overcome challenges associated with bioavailability, stability, and targeted delivery. In the 2nd section, injectable emulsions are discussed as a formulation to overcom

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Allyn, M. M., and K. E. Swindle-Reilly. "Protecting Sight: Advances in Drug Delivery to the Posterior Segment to Combat Vision Loss." In Ophthalmic Biomaterials. Royal Society of Chemistry, 2025. https://doi.org/10.1039/9781839169779-00349.

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A notable increase has been seen in retinal diseases or other conditions necessitating treatments for the posterior segment of the eye. While intravitreal injections have become the standard of care for posterior segment delivery, new technologies are being developed to minimize intravitreal injection frequency or to deliver to the posterior segment without intravitreal injection. Research and development efforts have increased for sustained release to the eye to overcome current treatment challenges, including reducing the burden on ophthalmologists, showing promise in improving drug release

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Saltzman, W. Mark. "Controlled Drug Delivery Systems." In Drug Delivery. Oxford University Press, 2001. http://dx.doi.org/10.1093/oso/9780195085891.003.0015.

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In most forms of drug delivery, spatial localization and duration of drug concentration are constrained by organ physiology and metabolism. For example, drugs administered orally will distribute to tissues based on the principles of diffusion, permeation, and flow presented in Part II of this book. If the duration of therapy provided by a single administration is insufficient, the drug must be readministered. Localization of drug can be controlled by injection, but only within limited spatial constraints, and effectiveness after an injection is usually short-lived. Controlled-delivery systems

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Jyoti, Ms, John Chelsea Ruth, and Vemula Pooja. "THE NOVEL TECHNIQUES FOR ENHANCING POORLY SOLUBLE DRUGS – NANOSUSPENSION, VESICULAR DRUG DELIVERY SYSTEM (TRANSFERSOMES, INVASOMES & NIOSOMES)." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 21. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3becs21p10ch3.

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The conventional drug delivery system has several limitations, like poor solubility and the inability to achieve sustained and prolonged drug release. To overcome these limitations of conventional drug delivery systems, novel techniques have come into the existence. Solubility is the major issue seen in poorly soluble drugs, which leads to low efficiency. This book chapter explains the various solubility enhancement techniques, including nanosuspension and vesicular drug delivery systems (Transferosomes, Invasomes, and niosomes).

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Zohera, Fatema Tuz, and Abul Kalam Azad. "Alginate-Based Microbeads." In Polymer-Based Drug Delivery. IGI Global, 2025. https://doi.org/10.4018/979-8-3373-1047-3.ch006.

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Alginate-based microbeads are promising carriers for targeted drug delivery due to their biocompatibility, biodegradability, and gel-forming capacity. Formed via ionotropic gelation with divalent cations, these microbeads protect labile drugs and enable sustained, controlled, and site-specific release. Tuning parameters like the M/G ratio and crosslinking density allows precise control of drug release kinetics and mechanical properties. Recent advances—including co-polymers, nanoparticles, and stimuli-responsive systems—have improved targeting, drug retention, and stability. Applications span

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Raza, Sajid, Palwasha Bibi, Jawad Riaz, Ali Shan, and Abul Kalam Azad. "Polymer-Based Microneedles in Transdermal Drug Delivery Systems." In Polymer-Based Drug Delivery. IGI Global, 2025. https://doi.org/10.4018/979-8-3373-1047-3.ch009.

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Polymeric microneedles (MNs) constitute an advanced technology in transdermal drug delivery that overcomes the limitations of traditional patches bypassing the stratum corneum to facilitate precise and minimum penetrative administration. By employing biodegradable polymers, such as PLGA, PCL, and hyaluronic acid, MNs offer enhanced biocompatibility, sustainability, and controlled drug release, addressing various medical applications, including vaccines, cosmeceuticals, and gene therapy. Significant advancements include biosensor integration for real-time monitoring, nanotechnology for improved

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Rabiei, Morteza, and Seyedeh Sabereh Samavati. "The Application of Nanotechnology in the Pharmaceutical Treatment of Common Diseases." In Dosage Forms - Emerging Trends and Prospective Drug-Delivery Systems [Working Title]. IntechOpen, 2024. https://doi.org/10.5772/intechopen.1005467.

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The use of chemical drugs to treat disease always imposes certain limitations, including, but not limited to, drug side effects, loss of a significant portion of the dose, inappropriate method of administration to the patient, and the development of resistance to the prescribed dose. Recently, nanotechnology has been utilized to develop drug delivery systems to overcome these limitations through the improvement of methods for controlled release. Limited drug absorption by nervous, bone, and cartilage tissues has led to modification of the delivery methods to increase the accumulation of drugs

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Kosiborod, Mikhail. "Case 52: Refractory Angina in a Patient with Type 2 Diabetes." In Diabetes Case Studies: Real Problems, Practical Solutions. American Diabetes Association, 2015. http://dx.doi.org/10.2337/9781580405713.52.

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A 76-year-old man presents for a routine outpatient cardiology visit. He has a 15-year history of type 2 diabetes, with several diabetes-related microvascular complications, including stage III chronic kidney disease and mild peripheral neuropathy. He is currently on a combination of metformin and sulfonylurea (SU; sustained release glipizide) for glucose control, with last hemoglobin A1c (HbA1c) of 8.5%. Although the patient never sustained a myocardial infarction, he has a complex and longstanding history of multivessel coronary artery disease (CAD), requiring two-vessel coronary artery bypa

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Streszczenia konferencji na temat "Including sustained release"

Ansari, Mohammad Javed, Aziz Unnisa, Anshul Singh, Devvret Verma, Rahul Kanaoujiya, and Jose Luis Arias Gonzales. "Application of Porous Nanomaterials for Sustained and Targeted Drug Release." In International Conference on Recent Advancements in Biomedical Engineering. Trans Tech Publications Ltd, 2022. http://dx.doi.org/10.4028/p-b2484c.

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Patients must take significant doses of drugs to acquire the therapeutic effects required for disease therapy due to the absence of selectivity and accessibility of medicinal molecules. Drugs contain a range of drug carriers that are available to transport therapeutic chemicals to the targeted issues in the body. Mesoporous materials are choice for overcoming the aforementioned issues and producing effects in a predictable and long-term way. Because of its chemical characteristics, thermal stability, & biocompatibility, mesophoric nanoparticles are commonly utilized as release reagents. Th

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Vladu, Alina, Emilia Visileanu, Alexandra Gabriela Ene, Madalina Georgiana Albu Kaya, Viviana Roman, and Carmen Gaidau. "Biological evaluation of antimicrobial treated textiles." In 16th International Conference on Applied Human Factors and Ergonomics (AHFE 2025). AHFE International, 2025. https://doi.org/10.54941/ahfe1006194.

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Textiles provide a suitable environment for the growth of microorganisms, including fungi and bacteria. Their presence can have detrimental effects on both the fabric and the user. These effects may include unpleasant odors, fabric discoloration, a higher risk of contamination, and a decline in the material's mechanical strength. The transmission of infections through textiles can be mitigated by using antimicrobial fabrics, which either eliminate pathogens on contact or inhibit their reproduction before they spread to another surface or individual. Antimicrobial textiles are created by applyi

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Lall, Pradeep, Aathi Raja Ram Pandurangan, and Ken Blecker. "Predictive Cohesive Zone Modeling for Delamination at PCB-Potting Material Interfaces Under Four-Point Bend Loading With Sustained High-Temperature Exposure." In ASME 2022 International Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Microsystems. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/ipack2022-97427.

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Abstract Potting is one of the most effective techniques for safeguarding electronics assembly in challenging harsh conditions, including shock and vibration. Interconnect failures are often preceded by delamination at the PCB and epoxy interface. PCB-Epoxy interfaces have not been extensively researched for interfacial fracture resistance under high thermo-mechanical loading. In this study, bi-material PCB-epoxy samples are made and exposed to long-term high-temperature aging followed by monotonic four-point bend loading. The evolution of the interfacial integrity under sustained high-tempera

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Ye, Jianfeng, Baoguo Chen, and Lisa X. Xu. "Shear Stress Effect on the Production of Nitric Oxide in Cultured Rat Aorta Endothelial Cells." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33074.

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Atherosclerotic lesions tend to develop in regions where there are separations from unidirectional laminar blood flow, typically near branches, bifurcations, regions of arterial narrowing, and curvatures in the arteries (1, 2). Obviously, homodynamic forces play a key role in atherosclerosis. Studies also indicate that vascular endothelium function disturbance, especially impairment of endothelium dependent vasodilation, is involved (3). Shear stress affects endothelial cells in many ways, such as cytoskeletal rearrangement, decrease of intracellular pH, release of PGI2 and some growth factors

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Benko, Tim, Alex MacGregor, Eric Wen, Thomas Fox, and Brendan Moorhouse. "Continuous Methane Measurement: Equivalency Evaluation of Regulator-Approved Alternative Leak Detection and Repair Program in Alberta, Canada." In SPE Annual Technical Conference and Exhibition. SPE, 2022. http://dx.doi.org/10.2118/209973-ms.

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Abstract Diverse methods have emerged for methane Leak Detection and Repair (LDAR), alongside a growing interest in continuous measurement (CM). Novel LDAR programs must demonstrate equivalent (or better) emissions reductions compared to conventional handheld methods to be approved by regulators and trusted by industry. We apply and test a widely accepted equivalency framework and report on a regulatory approved alternative LDAR pilot program to evaluate the performance of CM relative to conventional LDAR. The framework, which has not been formally tested to date, relies on a combination of co

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Wei, Sheng, Brandon Sforzo, and Jerry Seitzman. "Fuel Composition Effects on Forced Ignition of Liquid Fuel Sprays." In ASME Turbo Expo 2018: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/gt2018-77196.

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In gas turbine combustors, ignition is achieved by using sparks from igniters to start a flame. The process of sparks interacting with fuel/air mixture and creating self-sustained flames is termed forced ignition. Physical and chemical properties of a liquid fuel can influence forced ignition. The physical effects manifest through processes such as droplet atomization, spray distribution, and vaporization rate. The chemical effects impact reaction rates and heat release. This study focuses on the effect of fuel composition on forced ignition of fuel sprays in a well-controlled flow with a comm

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Golbuff, Sam, Elizabeth D. Kelly, and Samuel V. Shelton. "Cost Optimization of a Plug-In Hybrid Electric Vehicle." In ASME 2008 2nd International Conference on Energy Sustainability collocated with the Heat Transfer, Fluids Engineering, and 3rd Energy Nanotechnology Conferences. ASMEDC, 2008. http://dx.doi.org/10.1115/es2008-54326.

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In order to decrease the use of petroleum and release of greenhouse gases such as carbon dioxide, the efficiency of transportation vehicles must be increased. One way to increase vehicle efficiency is by extending the electric-only operation of hybrid electric vehicles through the addition of batteries that can be charged using grid electricity. These plug-in hybrid electric vehicles (PHEVs) are currently being developed for introduction into the U.S. market. As with any consumer good, cost is an important design metric. This study optimizes a PHEV design for a mid-size, gasoline-powered passe

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Lowry, Jodie, Ana Leticia S. Menezes, and Jorge Gainza. "Safe for Life: An HSE Campaign Case Study." In SPE International Health, Safety, Environment and Sustainability Conference and Exhibition. SPE, 2024. http://dx.doi.org/10.2118/220343-ms.

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Abstract This paper describes how a global energy technology company developed and implemented a global communications campaign called Safe for Life. The campaign’s intent was to promote safe behaviors by delivering short videos, featuring employees in company facilities and at home with their families. The campaign aimed to extend safety culture beyond the workplace by reinforcing Life-Saving Rules and other safety messages in a way that resonated with personnel, their families and friends, as well as the company’s customers. The initiative involved creating eleven short impactful videos, usi

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Harrist, J., M. Snijder van Wissenkerke, and R. Barbee. "Challenges and Successes of Integrating Natural Gas Generators with Energy Storage Systems." In SPE/IADC International Drilling Conference and Exhibition. SPE, 2025. https://doi.org/10.2118/223811-ms.

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Abstract Energy storage systems are an innovative solution that have been deployed at scale on land rigs in the U.S. in recent years. Designed to reduce fuel consumption and emissions by using lithium-ion batteries to store energy during low-demand periods and release it during peak demand, these systems help optimize generator usage, keeping generators in their most efficient operating range. Historically, energy storage systems have only been deployed on diesel and dual-fuel rigs, which are the most common generator types in the industry. Natural gas generators have proven to be a viable alt

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Ahn, Hyeonjeong, and Hyunkyoung Shin. "Fatigue Analysis of a 12-MW Wind Turbine Blade." In ASME 2018 37th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/omae2018-78214.

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In 2017, the MHI Vestas released a 9.5-MW offshore wind turbine. It is also actively researching and developing a 10-MW offshore wind turbine. As the capacity of a wind turbine increases, the sizes of all its system components, including length and weight, correspondingly increase. Consequently, as a wind turbine becomes larger, it becomes necessary to analyze the fatigue load applied to its entire system. The first reason for such an analysis is to achieve a safe but not overly designed large wind turbine. Second, most wind turbine accidents involve aging turbines and are related to fatigue a

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Raporty organizacyjne na temat "Including sustained release"

Yaron, Zvi, Abigail Elizur, Martin Schreibman, and Yonathan Zohar. Advancing Puberty in the Black Carp (Mylopharyngodon piceus) and the Striped Bass (Morone saxatilis). United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7695841.bard.

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Both the genes and cDNA sequences encoding the b-subunits of black carp LH and FSH were isolated, cloned and sequenced. Sequence analysis of the bcFSHb and LHb5'flanking regions revealed that the promoter region of both genes contains canonical TATA sequences, 30 bp and 17 bp upstream of the transcription start site of FSHb and LHb genes, respectively. In addition, they include several sequences of cis-acting motifs, required for inducible and tissue-specific transcriptional regulation: the gonadotropin-specific element (GSE), GnRH responsive element (GRE), half sites of estrogen and androgen

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Debuque-Gonzales, Margarita, John Paul Corpus, and Ramona Maria Miral. Macroeconomic Prospects of the Philippines in 2022-2023: Steering through Global Headwinds. Philippine Institute for Development Studies, 2022. https://doi.org/10.62986/dp2022.31.

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This paper, which will be released as the lead chapter of the 2021–2022 PIDS Economic Policy Monitor, reviews the Philippines’ macroeconomic performance in 2021 and the first half of 2022, analyzes recent developments and challenges shaping the economy’s near-term outlook, and presents macroeconomic projections for 2022 and 2023. With the country’s sustained economic reopening, the analysis suggests that GDP growth may grow by about 7.1 percent, but economic activity may weaken in 2023 as the global economic environment deteriorates. Inflation will likely continue to be elevated in 2022 but ma

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Morin, S., L. L. Walling, Peter W. Atkinson, J. Li, and B. E. Tabashnik. ets for CRISPR/Cas9-mediated gene drive in Bemisia tabaci. United States-Israel Binational Agricultural Research and Development Fund, 2021. http://dx.doi.org/10.32747/2021.8134170.bard.

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The goal of our BARD proposal was to build both the necessary infrastructure and knowledge for using the CRISPR/Cas9-based gene drive system to control the whitefly Bemisia tabaci. Our research focused on achieving three main goals: (1) establishing a CRISPR/Cas9 gene-editing system for producing genetically-edited B. tabaci; (2) generating and testing CRISPR/Cas9-mediated mutations targeting genes that represent two gene drive strategies: population replacement and population suppression; (3) using computer modeling to optimize strategies for applying CRISPR/Cas9 to control B. tabaci populati

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