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Rozprawy doktorskie na temat „Intestinal colic”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Gomaa, Naglaa Abdel Megid. "Clinical and clinicopathological studies in healthy horses and horses with colic." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-69992.

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In order to investigate the effect of food restriction on fat mobilization in horses with impaction in left ventral colon during treatment, serum triglycerides, NEFA and total bilirubine (TB) were measured before and after treatment. On another side, the determination of alcohol dehydrogenase (ADH) activity in serum could facilitate the distinguishing of the non-strangulating intestinal obstruction from the potential fatal strangulation obstruction and could submit a new prognostic biochemical parameter for intestinal strangulation. With the intention of giving a highlight over the analgesic e

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Di, Filippo Paula Alessandra [UNESP]. "Obstrução intestinal experimental em equinos: parâmetros clínicos e laboratoriais." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/101151.

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Made available in DSpace on 2014-06-11T19:31:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-01-23Bitstream added on 2014-06-13T20:01:43Z : No. of bitstreams: 1 difilippo_pa_dr_jabo.pdf: 454284 bytes, checksum: b9aeabbf9ca5c1fc6bc3d51066aa8568 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Com o objetivo de avaliar e comparar as alterações clínicas e hematológicas de equinos submetidos a modelo experimental de obstrução intestinal, 24 animais foram distribuídos em quatro grupos, controle instrumentado (GI), obstrução do duodeno (GII), íleo (GIII) e cólon

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Di, Filippo Paula Alessandra. "Obstrução intestinal experimental em equinos : parâmetros clínicos e laboratoriais /." Jaboticabal : [s.n.], 2009. http://hdl.handle.net/11449/101151.

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Orientador: Áureo Evangelista Santana<br>Banca: José Corrêa de Lacerda Neto<br>Banca: Antonio Carlos Alessi<br>Banca: Márcia Ferreira da Rosa Sobreira<br>Banca: Raimundo Souza Lopes<br>Resumo: Com o objetivo de avaliar e comparar as alterações clínicas e hematológicas de equinos submetidos a modelo experimental de obstrução intestinal, 24 animais foram distribuídos em quatro grupos, controle instrumentado (GI), obstrução do duodeno (GII), íleo (GIII) e cólon maior (GIV). O exame clínico e a colheita das amostras de sangue e de líquido peritoneal foram realizados antes da cirurgia (T0), durante

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Nogueira, Andressa Francisca Silva [UNESP]. "Proteínas de fase aguda no soro sanguíneo e no líquido peritoneal de equinos submetidos à obstrução intestinal experimental." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/89214.

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Made available in DSpace on 2014-06-11T19:23:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-03-01Bitstream added on 2014-06-13T19:30:22Z : No. of bitstreams: 1 nogueira_afs_me_jabo.pdf: 474641 bytes, checksum: fa1d22177f28628ebd508fc2adfc16f4 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>A síndrome cólica é uma das urgências mais frequentes na clínica de equinos. Os estágios iniciais da reação inflamatória incluem alterações denominadas resposta de fase aguda. Com o objetivo de avaliar esta resposta realizou-se o perfil eletroforético das proteína

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Nogueira, Andressa Francisca Silva. "Proteínas de fase aguda no soro sanguíneo e no líquido peritoneal de equinos submetidos à obstrução intestinal experimental /." Jaboticabal : [s.n.], 2010. http://hdl.handle.net/11449/89214.

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Resumo: A síndrome cólica é uma das urgências mais frequentes na clínica de equinos. Os estágios iniciais da reação inflamatória incluem alterações denominadas resposta de fase aguda. Com o objetivo de avaliar esta resposta realizou-se o perfil eletroforético das proteínas séricas e do líquido peritoneal de equinos submetidos obstrução intestinal experimental. Utilizaram-se 21 equinos, cuja obstrução intestinal foi instituída em segmentos de duodeno - GD (n=6), íleo - GI (n=6) ou cólon dorsal esquerdo - GM (n=6). Além disso, instituiu-se um grupo controle instrumentado - GC (n=3). As colheitas

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Mena, Fabio Augusto Aristizábal. "Anastomose término-terminal no jejuno de eqüinos coberta com retalhos mesentéricos pediculados." Universidade Federal de Viçosa, 2006. http://locus.ufv.br/handle/123456789/5177.

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Made available in DSpace on 2015-03-26T13:47:22Z (GMT). No. of bitstreams: 1 texto completo.pdf: 1054251 bytes, checksum: 89af20b09635b80159627f67aeb85cad (MD5) Previous issue date: 2006-01-31<br>Resection and anastomosis of the small intestine is commonly performed in horses to treat lesions produced by strangulated obstructions and other diseases. However this procedure is associated with several complications such as peritoneal adhesions, intestinal stenosis at the site of the anastomosis, necrosis of the preserved intestinal stumps, leakage of intestinal contents and septic peritonitis.

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Rothe, Monique. "Response of intestinal Escherichia coli to dietary factors in the mouse intestine." Phd thesis, Universität Potsdam, 2013. http://opus.kobv.de/ubp/volltexte/2013/6638/.

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Diet is a major force influencing the intestinal microbiota. This is obvious from drastic changes in microbiota composition after a dietary alteration. Due to the complexity of the commensal microbiota and the high inter-individual variability, little is known about the bacterial response at the cellular level. The objective of this work was to identify mechanisms that enable gut bacteria to adapt to dietary factors. For this purpose, germ-free mice monoassociated with the commensal Escherichia coli K-12 strain MG1655 were fed three different diets over three weeks: a diet rich in starch, a di

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Chen, Zhijian, and 陈智健. "Modulation of intestinal epithelial cell-mediated defence responses bymetabolic products of Lactobacillus rhamnosus GG and Escherichia coliNissle 1917." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B49799678.

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Probiotics are defined as live microorganisms that confer beneficial effects to health when administered in a sufficient amount. In previous studies about the beneficial effects of probiotic bacteria to health, particularly in the fields of intestinal mucosa defence responses, specific probiotics, in a strain-dependent manner, show some potential to reinforce the integrity of intestinal epithelium and/or regulate some immune components. However, the mechanisms involved in the interactions between probiotics or bioactive components of probiotics with the intestinal epithelium are still not yet

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Rothe, Monique [Verfasser], and Michael [Akademischer Betreuer] Blaut. "Response of intestinal Escherichia coli to dietary factors in the mouse intestine / Monique Rothe. Betreuer: Michael Blaut." Potsdam : Universitätsbibliothek der Universität Potsdam, 2013. http://d-nb.info/1037027485/34.

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Mirande, Caroline. "Dégradation des fibres pariétales et système xylanolytique de Bacteroides xylanisolvens XB1A et Roseburia intestinalis XB6B4, espèces bacteriennes du microbiote intestinal humain." Clermont-Ferrand 2, 2009. http://www.theses.fr/2009CLF22007.

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Chez l'Homme, les parois végétales contenues dans les fibres alimentaires sont dégradées puis fermentées par les bactéries fibrolytiques du côlon. Le xylane étant l'un des principaux polysaccharides constituant ces parois végétales, deux bactéries possédant de fortes activités xylanolytiques, Bacteroides xylanisolvens XB1A T et Roseburia intestinalis XB6B4, ont été caractérisées. Les activités xylanolytiques de ces espèces vis-à-vis de différents substrats riches en xylanes ont été analysées quantitativement et qualitativement. L'équipement enzymatique de ces souches, comparé par zymogramme, r

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Mirande, Caroline. "Dégradation des fibres pariétales et système xylanolytique de Bacteroides xylanisolvens XB1AT et Roseburia intestinalis XB6B4, espèces bactériennes du microbiote intestinal humain." Phd thesis, Université Blaise Pascal - Clermont-Ferrand II, 2009. http://tel.archives-ouvertes.fr/tel-00719726.

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Chez l'Homme, les parois végétales contenues dans les fibres alimentaires sont dégradées puis fermentées par les bactéries fibrolytiques du côlon. Le xylane étant l'un des principaux polysaccharides constituant ces parois végétales, deux bactéries possédant de fortes activités xylanolytiques, Bacteroides xylanisolvens XB1A T et Roseburia intestinalis XB6B4, ont été caractérisées. Les activités xylanolytiques de ces espèces vis-à-vis de différents substrats riches en xylanes ont été analysées quantitativement et qualitativement. L'équipement enzymatique de ces souches, comparé par zymogramme, r

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12

Mayorgas, Aida. "Human Primary Organoid-Derived Epithelial Monolayers as a Novel Strategy for the Study of Adherent Invasive Escherichia coli pathogenicity and the effects of Postbiotics on Intestinal Epithelial Function." Doctoral thesis, Universitat de Barcelona, 2021. http://hdl.handle.net/10803/672414.

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Inflammatory bowel disorders – such as Inflammatory Bowel Disease (IBD) – are rising worldwide. A well-known feature of IBD is dysbiosis of the gut microbiota, characterized by a significant reduction of beneficial strains and a sharp increase in facultative anaerobes, as is the case of Adherent Invasive E. coli (AIEC). Even though the implication of the microbiota in persistent inflammation has been studied for years, a direct causal relationship between dysbiosis and IBD has not been established. To date, several strategies, such as the use of probiotics, have been proposed to counteract the

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Pujo, Julien. "Caractérisation de molécules lipidiques produites par les bactéries probiotiques Escherichia coli Nissle 1917 : rôle dans l’homéostasie intestinale." Thesis, Toulouse 3, 2018. http://www.theses.fr/2018TOU30199.

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De nombreuses études portant sur le microbiote intestinal ont mis en évidence son importance dans la physiologie et la physiopathologie de l’hôte. Les bactéries, acteurs majeurs du microbiote, participent au maintien de l’homéostasie intestinale en régulant plusieurs fonctions essentielles allant de la protection de la barrière intestinale au développement du système immunitaire. Des altérations de la composition et de la diversité de ce microbiote ont été observées dans des pathologies du tractus digestif comme le syndrome de l’intestin irritable et les maladies inflammatoires chroniques de l

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Ribeiro, Tamara Renata Machado. "Sinalização química e virulência de Escherichia coli O104:H4 (EAEC Stx+) /." Araraquara, 2017. http://hdl.handle.net/11449/150987.

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Orientador: Cristiano Gallina Moreira<br>Banca: Waldir Pereira Elias Nunes<br>Banca: Carla Raquel Fontana Mendonça<br>Resumo: A sinalização química é o mecanismo através do qual bactérias patogênicas interagem com o hospedeiro e sua microbiota, de modo a promover a regulação dos seus mecanismos de virulência. O estudo da sinalização química, em bactérias entéricas, do sistema de 2-componentes QseBC via autoindutor-3 (AI-3), epinefrina (Epi) e norepinefrina (NE), tem aberto perspectivas para desvendar novos mecanismos. Escherichia coli O104:H4 possui características fenotípicas clássicas de E.

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Thomazini, Cristiane Melissa [UNESP]. "Pesquisa de fatores de patogenicidade em Escherichia coli Enteroagregativas da microbiota intestinal de pacientes com doença inflamatória intestinal." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/104575.

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Made available in DSpace on 2014-06-11T19:33:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-07-30Bitstream added on 2014-06-13T20:44:51Z : No. of bitstreams: 1 thomazini_cm_dr_botfm.pdf: 892086 bytes, checksum: 330ae89e0fa48c19f97f1eac213d0a4c (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Intestinal population of Escherichia coli is increased in patients suffering from inflammatory bowel disease (IBD), but the reason for this elevation and particular features of these bacteria are not fully known. In this study, the adherence abilities and phenoty

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Thomazini, Cristiane Melissa. "Pesquisa de fatores de patogenicidade em Escherichia coli Enteroagregativas da microbiota intestinal de pacientes com doença inflamatória intestinal /." Botucatu : [s.n.], 2010. http://hdl.handle.net/11449/104575.

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Resumo: Não disponível<br>Abstract: Intestinal population of Escherichia coli is increased in patients suffering from inflammatory bowel disease (IBD), but the reason for this elevation and particular features of these bacteria are not fully known. In this study, the adherence abilities and phenotypes of a collection of 131 E. coli isolates cultured from rectal biopsies of 27 subjects diagnosed with ulcerative colitis (UC), 8 with Crohn's disease (CD) and 19 control patients were investigated, using HEp-2 cells in assays of 3 and 6h of bacteria-cell contact. The isolates were also PCR screened

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Zheng, Jie. "Campylobacter jejuni/coli - host intestinal epithelial cell interaction." College Park, Md. : University of Maryland, 2006. http://hdl.handle.net/1903/3931.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2006.<br>Thesis research directed by: Food Science. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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Rahmouni, Oumaïra. "Portage fécal du pathovar Escherichia coli adhérent et invasif (AIEC) chez des patients atteints de maladies inflammatoires chroniques de l’intestin et des témoins sains." Thesis, Lille 2, 2018. http://www.theses.fr/2018LIL2S012/document.

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L’étiologie exacte des maladies inflammatoires chroniques de l’intestin (MICI) reste actuellement méconnue. Mais un déséquilibre de la flore bactérienne, plus connu sous le nom de dysbiose et se traduisant par une augmentation de bactéries potentiellement pathogènes versus une diminution de bactéries bénéfiques, est démontré en permanence. De précédentes études ont permis de mettre en évidence la présence de souches pathogènes d’E. coli chez les patients atteints de la maladie de Crohn (MC). Ces souches appartiennent au pathovar Adherent Invasive E. coli (AIEC) et sont caractérisées par leur c

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Almeida, Edison de. "Utilização do probiótico Protexin® em leitões na fase de creche, submetidos ao desafio com Escherichia coli." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/10/10135/tde-22032007-111550/.

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O experimento foi realizado na unidade de creche do Laboratório de Pesquisa em Suínos (LPS) da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP), campus de Pirassununga (SP), sendo utilizados setenta e dois leitões recém desmamados (21 dias), com peso médio de 6,5 kg. O delineamento experimental foi em blocos casualizados, num arranjo fatorial 2 x 2, sendo os fatores: probiótico e desafio, os quais definiram os tratamentos: T 1 - emprego do probiótico, com desafio (CPCD); T 2 - emprego do probiótico, sem o desafio (CPSD); T 3 - ausência do probiótico, com de

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Clark, Ewan M. "Characterisation of Escherichia coli of the bovine intestinal tract." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/706/.

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Enterohaemorrhagic E. coli (EHEC) are important gastrointestinal pathogens of humans. E. coli serotype O157:H7 is the EHEC most commonly associated with human illness. E. coli O157:H7 is carried asymptomatically by cattle which form an important reservoir for the bacterium. E. coli O157:H7 has been found to colonise at the terminal rectum of cattle in preference to other sites in the bovine gastrointestinal tract. The first objective of this work was to characterise the roles of bacterial secreted components responsible for key functions in the modulation of host defences against EHEC. Data pr

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Colby, Susan Mary. "Pathogenicity studies on verocytotoxin-producing Escherichia coli : bacterial adhesion, toxin expression and uptake." Thesis, University of Warwick, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387370.

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Rinnovati, Riccardo <1985&gt. "Relazione tra parassitismo intestinale e colica nel paziente equino." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/6011/1/Rinnovati_Riccardo_tesi.pdf.

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Obiettivo: capire la relazione che intercorre tra le coliche del cavallo e le parassitosi intestinali, quindi capire l’effettiva rilevanza clinica delle infezioni parassitarie. Tipo di studio: studio clinico-chirurgico e parassitologico. Metodi: in questo studio sono stati presi in esame 92 cavalli afferiti presso il servizio SARGA del Dipartimento di Scienze Mediche Veterinarie durante gli anni 2009-2011. 27 di questi soggetti sono stati sottoposti a laparotomia esplorativa per colica, 22 avevano una colica che si è risolta con terapia medica, sono stati 43 i cavalli afferiti presso il

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Rinnovati, Riccardo <1985&gt. "Relazione tra parassitismo intestinale e colica nel paziente equino." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/6011/.

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Obiettivo: capire la relazione che intercorre tra le coliche del cavallo e le parassitosi intestinali, quindi capire l’effettiva rilevanza clinica delle infezioni parassitarie. Tipo di studio: studio clinico-chirurgico e parassitologico. Metodi: in questo studio sono stati presi in esame 92 cavalli afferiti presso il servizio SARGA del Dipartimento di Scienze Mediche Veterinarie durante gli anni 2009-2011. 27 di questi soggetti sono stati sottoposti a laparotomia esplorativa per colica, 22 avevano una colica che si è risolta con terapia medica, sono stati 43 i cavalli afferiti presso il

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Ellis, Samuel. "Investigating enteroaggregative Escherichia coli virulence factors in human intestinal infection." Thesis, University of East Anglia, 2018. https://ueaeprints.uea.ac.uk/69931/.

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Enteroaggregative Escherichia coli (EAEC) are a major cause of diarrhoeal illness in children, travellers, and the immunocompromised, and associated with foodborne outbreaks worldwide. However, EAEC is a heterogeneous pathotype with frequent asymptomatic carriage and a diversity of virulence factors. Previous studies have been unsuccessful in identifying genetic virulence markers. In this study, two complimentary approaches were applied using intestinal infection models to investigate bacterial factors contributing to EAEC pathogenesis in the human gut. Firstly, the influence of intestinal env

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Mahajan, Arvind. "Interaction of enterohaemorrhagic Escherichia coli (EHEC) with bovine intestinal epithelium." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/29863.

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Verotoxins (VT; or shiga-like toxins - Stx) are major virulence factors and are key determinants in the patho-physiology of EHEC infections in humans. Cattle are the most important asymptomatic reservoir host for EHEC and recently terminal rectum was identified as the principal site of <i>E. coli</i> O157:H7 colonization in cattle. First objective of this research project was to immuno-phenotypically characterise terminal rectal tissue of cattle. Secondly, to develop and characterise primary rectal epithelial cell culture as an <i>in vitro</i> model to study interaction with EHEC strains. Ini

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Denizot, Jérémy. "Perméabilité intestinale et régulation de l'expression du gène CEACAM6 : implication des bactéries Escherichia coli associées à la maladie de Crohn." Thesis, Clermont-Ferrand 1, 2013. http://www.theses.fr/2013CLF1MM04/document.

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La maladie de Crohn (MC) est une maladie inflammatoire chronique du tube digestif caractérisée par un état d'hyperactivation du système immunitaire intestinal et évoluant par poussées aigües entrecoupées de périodes de rémission. Les données cliniques et expérimentales montrent que l'étiologie de la MC serait une réponse immunitaire aberrante en réponse à des facteurs environnementaux tels que la consommation de nourriture riche en graisses et en sucres, et infectieux chez un hôte génétiquement prédisposé. Les patients atteints de MC présentent une perméabilité intestinale anormalement élevée,

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Sampaio, Ingrid Cordeiro. "Avaliação do transporte transmembrânico de glicose, glutamina e alanil-glutamina em íleo de camundongos nutridos e desnutridos infectados por Escherichia coli enteropatogênica." reponame:Repositório Institucional da UFC, 2013. http://www.repositorio.ufc.br/handle/riufc/17971.

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SAMPAIO, I. C. Avaliação do transporte transmembrânico de glicose, glutamina e alanil-glutamina em íleo de camundongos nutridos e desnutridos infectados por Escherichia coli enteropatogênica. 2013. 94 f. Dissertação (Mestrado em Microbiologia Médica) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2013.<br>Submitted by Erika Fernandes (erikaleitefernandes@gmail.com) on 2016-06-27T13:12:05Z No. of bitstreams: 1 2013_dis_icsampaio.pdf: 2023722 bytes, checksum: 5a90dfd95b7f17ad24c74e2d9e2301a5 (MD5)<br>Approved for entry into archive by Erika Fernandes (erikaleitefernandes@gmai

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Diaz, Garrido Natalia. "Modulation of intestinal immune responses by microbiota-derived extracellular vesicles." Doctoral thesis, Universitat de Barcelona, 2021. http://hdl.handle.net/10803/673948.

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The gut microbiota establishes dynamic and complex interactions with the intestinal epithelium and the immune system. In this regard, commensal microbiota plays essential role in the development and maturation of the host immune system, which must learn to discriminate between commensal and pathogenic bacteria. Appropriate development of the immune system is crucial to maintain intestinal homeostasis. Microbiota-host communication does not involve direct intercellular contacts since the intestinal epithelium is protected by a mucus layer that segregates luminal microbes from host cells. Theref

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Baillou, Renaud. "Exploration lagrangienne des environnements complexes par les micro-organismes : suivi Lagrangien de E. coli motiles sous confinement et pénétration de la barrière de mucus." Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS559.

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Les micro-organismes sont omniprésents sur Terre. Ils ont développé l'autopropulsion pour explorer leur environnement et coloniser de nouvelles niches écologiques. Certains d'entre eux sont pathogènes et déclenchent des inflammations lorsqu'ils entrent en contact avec des cellules épithéliales. Alors que la nature hydrodynamique de leur mouvement est plutôt bien comprise dans les fluides newtoniens, il reste encore beaucoup à comprendre lorsqu'ils interagissent mécaniquement avec leur environnement, soit par la présence d'obstacles géométriques, soit en raison de la nature non-newtonienne de l

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Hajj, Hussein Inaya Abdallah. "Experimental colitis and enteropathogenic E. Coli in rats : A new approach." Strasbourg 1, 2008. http://www.theses.fr/2008STR13153.

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Schumann, Sara. "Influence of intestinal inflammation on bacterial protein expression in monoassociated mice." Phd thesis, Universität Potsdam, 2013. http://opus.kobv.de/ubp/volltexte/2013/6775/.

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Background: Increased numbers of intestinal E. coli are observed in inflammatory bowel disease, but the reasons for this proliferation and it exact role in intestinal inflammation are unknown. Aim of this PhD-project was to identify E. coli proteins involved in E. coli’s adaptation to the inflammatory conditions in the gut and to investigate whether these factors affect the host. Furthermore, the molecular basis for strain-specific differences between probiotic and harmful E. coli in their response to intestinal inflammation was investigated. Methods: Using mice monoassociated either with the

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Samegima, Danyelle Amélia Grecco. "Algumas propriedades de virulência de Escherichia coli isoladas de pacientes com doença inflamatória intestinal." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-23092008-114610/.

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Escherichia coli tem um predomínio anormal em pacientes com doença inflamatória intestinal (DII), mas a razão deste aumento numérico é desconhecida. Amostras de E. coli (131) foram isoladas de biópsias retais de 27 pacientes com retocolite ulcerativa (RCU), 8 pacientes com doença de Chron (DC) e 19 controles. E. coli enteroagregativa (EAEC) foram detectadas no ensaio de adesão de 3 horas a células HEp-2 em 71,4% dos pacientes com DII e em 26,3% dos controles (P<0,02). As cepas de pacientes com DC foram negativas para outros marcadores. Duas cepas invasivas foram detectadas entre pacientes com

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BARILAR, PHILIPPE. "Infections intestinales a campylobacter jejuni-coli chez l'enfant." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20047.

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Kerneis, Sophie. "Étude des interactions des Escherichia coli entérovirulents avec les cellules intestinales humaines en culture : rôle des facteurs de virulence du phénotype cellulaire et de la différenciation cellulaire intestinale." Paris 11, 1993. http://www.theses.fr/1993PA114844.

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Lin, Tsung-Jung. "The binding mechanism of enterotoxigenic escherichia coli (ETEC) to swine intestinal epithelia." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107866.

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Colibacillosis (diarrhea in piglets caused by Escherichia coli) is the leading killer to piglets. Pathogenic E.coli responsible for this onset is referred as diarrheagenic E.coli. In six defined groups of diarrheagenic E.coli, enterotoxigenic E. coli (ETEC) is an important cause of post weaning diarrhea (PWD) in pigs. ETEC was first recognized by their ability to secrete two defined groups of enterotoxins: heat-stable toxin (STs) and heat-labile enterotoxin (LTs). F4 and F18 fimbriae, the most prevalent adhesins are commonly expressed on porcine ETEC to facilitate bacterial colonization. In a

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Fitzhenry, Robert James. "Interactions of enteropathogenic and enterohaemorrhagic escherichia coli with intestinal mucosae in vitro." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407237.

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Thevenot, Jonathan. "Etude en systèmes digestifs artificiels de la survie et de la pathogénicité des Escherichia Coli entérohémorragiques (EHEC). Influence de la matrice alimentaire et de l'administration de souches probiotiques." Thesis, Clermont-Ferrand 1, 2014. http://www.theses.fr/2014CLF1PP04/document.

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Les Escherichia coli entérohémorragiques (EHEC) sont des pathogènes zoonotiques responsables de toxi-infectionsalimentaires pouvant évoluer vers des atteintes potentiellement mortelles chez l’Homme. La survie des EHECet l’expression des gènes de virulence dans l’environnement digestif humain sont des facteurs essentiels dans laphysiopathologie de ces infections mais sont mal connus, essentiellement par manque de modèles d’études adaptés.L’absence de traitement spécifique a conduit à s’intéresser à des moyens préventifs et/ou curatifs alternatifs, commel’utilisation de probiotiques. L’objectif

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Escribano, Vazquez Unai. "Impact de souches commensales et probiotiques d'Escherichia coli sur la physiopathologie de l'hôte." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS348.

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Escherichia coli a pour habitat principal le tube digestif des mammifères, et constitue l’une des espèces sous-dominantes du microbiote intestinal adulte. E. coli présente un large spectre d'interactions avec l'hôte, pathogène, commensale ou probiotique. Dans des conditions de déséquilibre comme les maladies inflammatoires de l'intestin ou un régime hyperlipidique, les populations commensales d'E. coli augmentent et peuvent être considérés comme pathobiontes (micro-organismes commensaux ayant un potentiel pathogène). Cependant, le rôle de souches commensales d’E. coli vis-à-vis de la santé de

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Haines, Sara. "Identification of environmental and genetic factors influencing virulence gene expression in Enterotoxigenic Escherichia coli." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10017.

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Fernandes, Miriam Rodriguez. "A influência da antibioticoterapia na microbiota fecal de crianças em idade escolar." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-26082015-145646/.

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De todas as influências exógenas que possam alterar a microbiota intestinal, os antimicrobianos são capazes de causar as mais rápidas e drásticas mudanças. O impacto da exposição aos antimicrobianos na microbiota intestinal causa diminuição no número de microrganismos ou mesmo supressão, dependendo do antimicrobiano utilizado, da dose e do tempo de exposição. Assim, o objetivo deste estudo foi analisar de forma comparativa alguns microrganismos que compõem a microbiota fecal de crianças com e sem antibioticoterapia em idade escolar; bem como avaliar a susceptibilidade aos antimicrobianos e os

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Mastropaolo, Matthew David. "Studies of Three Human Intestinal Opportunistic Pathogens." Diss., Virginia Tech, 2008. http://hdl.handle.net/10919/28529.

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Opportunistic bacterial pathogens are present in the intestines of all mammals. These bacteria are symbionts to a certain extent, but under certain conditions these organisms can be deadly. Intestinal opportunistic pathogens encompass many genera and include organisms such as those in the Bacteroides fragilis group (i.e. B. fragilis and B. thetaiotaomicron), Escherichia coli, and Clostridium perfringens, resulting in an array of diseases and serious health risks. Typically these diseases affect individuals in poor or weakened health (elderly, immuno-compromised, neonates, etc.) but can affe

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Yang, Nan. "Role of Escherichia coli curli in relation with intestinal components - mucin, Klebsiella pneumoniae and Enterococcus faecalis." Phd thesis, INSA de Lyon, 2011. http://tel.archives-ouvertes.fr/tel-00657247.

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Bacteria in nature mostly exist in biofilms, which are structured adherent communities encased in polymeric matrices. In the human body, most biofilms are composed of commensal microorganisms with the gastrointestinal tract being the most heavily colonized site. Bacterial attachment to the overlying mucus gel layer of the intestinal epithelium is fundamental to the establishment of a stable commensal microflora. However the interaction of bacteria with the complex mucus gel is poorly described. Moreover, the complexity and diversity of the gut microbiota is itself an obstacle to studying its b

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Sancak, Aziz Arda. "Identification and characterisation of pathogenic Escherichia coli associated with intestinal disease in dogs." Thesis, Royal Veterinary College (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284817.

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Chong, Yuwen. "Intimate interactions between enteropathogenic and enterohemorrhagic Escherichia coli and intestinal epithelium in vitro." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445194/.

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Enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) are diarrhoeagenic human pathogens that colonize intestinal epithelial cells via an attaching and effacing (A/E) lesion. Intimate adherence is mediated through binding of the intimin adhesin to the bacterial translocated intimin receptor, Tir. EPEC adheres to all regions of the human intestine in the in vitro organ culture (IVOC) system. In contrast, although EHEC is associated with colonic pathology in human infections, a prototypical strain of EHEC has shown a restricted tropism towards follicle-associated epithel

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Murthy, Kruthi. "Phenotypic Characterization of Escherichia coli strains taken from human Intestinal and Urinary Tracts." Wright State University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=wright1164922969.

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Wang, Gaochan. "Diarrheagenic Escherichia coli signaling and interactions with host innate immunity and intestinal microbiota." Diss., Kansas State University, 2017. http://hdl.handle.net/2097/35735.

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Doctor of Philosophy<br>Department of Diagnostic Medicine/Pathobiology<br>Philip R. Hardwidge<br>Diarrheagenic Escherichia coli (E. coli) strains are common etiological agents of diarrhea. Diarrheagenic E. coli are classified into enterotoxigenic E. coli (ETEC), Shiga toxin-producing E. coli (STEC or enterohemorrhagic E. coli [EHEC]), enteropathogenic E. coli (EPEC), enteroinvasive E. coli (EIEC), enteroaggregative E. coli (EAEC), diffuse-adherent E. coli (DAEC), and adherent invasive E. coli (AIEC). In addition to encoding toxins that cause diarrhea, diarrheagenic E. coli have evolved numerou

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Gonçalves, Ana Catarina Martins. "Relação entre a infeção por Escherichia coli aderente-invasina e a doença de Crohn." Master's thesis, [s.n.], 2013. http://hdl.handle.net/10284/4089.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>A Doença de Crohn é uma doença inflamatória crónica que pode afetar qualquer parte do trato gastrointestinal, embora comprometa preferencialmente o íleo. Apesar da incessante investigação a sua etiologia e patogénese permanecem desconhecidas. Até ao momento várias hipóteses têm sido avançadas na compreensão desta doença. Contudo, a teoria atual considera que se trata de uma doença complexa multifatorial que ocorre em indivíduos c

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Abrahão, Luciana Rahal. "Efeitos hemodinâmicos sistêmicos e regionais da ressuscitação volêmica com solução salina hipertônica e isoncótica guiada pela saturação venosa mista de oxigênio em modelo experimental de choque séptico." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-16122008-164035/.

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Introdução: A disfunção de múltiplos órgãos induzida pela sepse é a principal causa de morte em Unidades de Terapia Intensiva. Complexas anormalidades hemodinâmicas, microcirculatórias e do metabolismo promovem dano tecidual e disfunção orgânica. Em particular, no território esplâncnico, os distúrbios da perfusão são precoces, desproporcionais ao comprometimento sistêmico e persistem apesar de uma ressuscitação sistêmica adequada, contribuindo para a disfunção de múltiplos órgãos. A reposição volêmica, fundamental no manejo inicial do choque séptico, é mais eficaz quando guiada por metas deriv

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Sivignon, Adeline. "Stratégies thérapeutiques visant à limiter les E.coli Adhérents-Invasifs du tractus digestif dans le cadre de la Maladie de Crohn." Thesis, Clermont-Ferrand 1, 2015. http://www.theses.fr/2015CLF1MM05.

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La maladie de Crohn (MC) est une maladie inflammatoire chronique du tube digestif caractérisée par un état d’hyperactivation du système immunitaire intestinal. Les données cliniques et expérimentales montrent que l’étiologie de la MC serait une réponse immunitaire aberrante à des facteurs environnementaux et/ou infectieux chez un hôte génétiquement prédisposé. Les patients atteints de MC présentent une perméabilité intestinale anormalement élevée pouvant expliquer la stimulation du système immunitaire intestinal par les bactéries et antigènes du microbiote. La muqueuse iléale des patients atte

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Silva, Renée de Nazaré Oliveira da. "Caracterização molecular dos genes ospC1, ospG e ospF em diferentes sorotipos de Escherichia coli enteroinvasora." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-26042013-093005/.

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Escherichia coli enteroinvasora (EIEC) é um dos agentes etiológicos da disenteria bacilar, caracteriza-se pela destruição do epitélio do cólon provocado pela resposta inflamatória induzida após invasão da mucosa por bactérias. Cepas de EIEC são bioquímica, genética e patogênica semelhante a Shigella spp. A patogenicidade de EIEC e Shigella dependem da presença da pInv plasmídeo, que contém os genes necessários para a colonização bacteriana na mucosa intestinal. Recentemente, demonstrou-se que genes plasmidias ospC1, ospG e ospF de S. flexneri estão envolvidos na inibição da resposta inflamatór

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