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Rozprawy doktorskie na temat „Lipid”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Kotland, Vojtěch. "Separace lipidů z buněčných tkání." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2019. http://www.nusl.cz/ntk/nusl-401857.

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This master’s thesis is focused on lipid separation from tissue cells. Thesis is divided into theoretical and experimental part. In the theoretical part is summarized current knowledge about lipids, their properties and methods used to separate them from tissue cells. Those methods were compared and one of them was chosen to be used in the experimental part. Theoretical part is ended with reviews aimed towards the research in this area of chemistry. Experimental part describes factors affecting chosen method of lipid separation from tissue cells. The measurements were chosen so that they could

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2

Dennison, Andrew. "Neutron reflectivity studies of insulin and phosphatidylcholine floating lipid bilayers." Thesis, University of Sheffield, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.574586.

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3

Wood, David. "Lipid Screening and Lipid Disorders in Children." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/etsu-works/7684.

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Deeney, Jude T. "Micro lipid droplet precursors of milk lipid globules." Thesis, Virginia Tech, 1985. http://hdl.handle.net/10919/45673.

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The lipid in milk (milk fat) is found in the form of droplets known as milk lipid globules (MLG). These milk lipid globules are encompassed by a unit membrane known as the milk lipid globule membrane (MLGM) which is derived from the apical plasma membrane of the mammary epithelial cell during secretion. In lactating mammary epithelial cells, immediate precursors of milk lipid globules appear to be cytoplasmic lipid droplets (CLD). These cytoplasmic lipid droplets have diameters >1 μm and are characterized by an electron dense, granular surface coat. A previously unrecognized group of

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5

Bandegi, Sanaz. "INTERACTION OF FLUORESCENT LIPID DYES WITH LIPID VESICLES AND SUPPORTED LIPID BILAYERS AND THEIR APPLICATIONS." Diss., Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/584744.

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Chemistry<br>Ph.D.<br>Lipophilic dye probes are widely used for labelling of cells, organelles, liposomes, viruses and lipoproteins. The lipophilic dye diffuses in the membrane and stains the cell and cells even tolerate the lipophilic dye in high concentration. The fluorescence of styryl dyes increases after insertion into the hydrophobic environment of the lipid membrane compared their fluorescence in the aqueous phase solution. The alkyl chains of the fluorescent styryl dye probe insert into membranes and are used to understand their biophysical properties and their behavior in lipid bilaye

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6

Oldham, Alexis Jean. "Modulation of lipid domain formation in mixed model systems by proteins and peptides." View electronic thesis, 2008. http://dl.uncw.edu/etd/2008-1/r1/oldhama/alexisoldham.pdf.

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7

Temprano, López Ana. "The lipin protein family in human adipocytes: lipid metabolism and obesity." Doctoral thesis, Universitat Rovira i Virgili, 2016. http://hdl.handle.net/10803/398025.

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Les lipins són una família conservada evolutivament de fosfatases de fosfatidat (PAP1) dependents de Mg2+, que generen diacilglicerol per a la síntesi de fosfolípids i triacilglicerol. En mamífers, la família consta de lipina-1, lipina-2 i lipina-3. Mentre en ratolins la mutació del gen Lpin1 causa lipodistròfia, les mutacions deletèries en el gen LPIN1 en humans no afecten la distribució del greix. No obstant, persones amb diabetis tipus 2 mostren nivells reduïts de l'expressió de LPIN1 i de l'activitat PAP1. Aquesta tesi estudia el paper de les lipins en el teixit adipós humà, la adipogènesi

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8

Carr, Neil Owen. "Lipid binding and lipid-protein interaction in wheat flower dough." Thesis, University of Reading, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293285.

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A study of lipid CClIplexirq in wheat floor ck:ujl has been made in an att:en¢ to explain the decrease in lipid extractability occurrin;J on dough developnent. '!be involvement of dough protein in this process has been assessa:i am new concepts have been evaluatai in the light of the known functionality of lipids in breadInakinI. PUblished W'Ork has irx:ticata:l that low IIDlecular \¥eight gluten proteins (ligolins) have a highly specific function in bin:ti.rg lipid. USl.rxJ similar fractionation methods to the plblished \¥Ork, it was possible to confirm this protein-lipid associaticn, althoug

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9

Reeder, Brandon Jon. "Reactions of lipid and lipid hydroperoxides with myoglobin and lipoxygenase." Thesis, University of Essex, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265191.

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10

PERISSINOTTO, FABIO. "Lipid raft formation and lipid-protein interactions in model membranes." Doctoral thesis, Università degli Studi di Trieste, 2018. http://hdl.handle.net/11368/2919798.

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The biological membranes of eukaryotic organisms contain functional, highly dynamic nano-domains called "lipid rafts" (LRs) which are enriched in cholesterol, sphingolipids and GPI-anchor proteins. They are involved in several biological processes which implicate or are mediated by the plasma membrane. Moreover, LRs seem to have a critical role in the onset of some neurodegenerative diseases such as the Alzheimer’s disease (AD), Parkinson’s disease (PD) and Prion protein disorders. In the last two decades, the complexity of studying such domains in living cells has caused a growing interest in

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11

Danial, John Shokri Hanna. "Imaging lipid phase separation on droplet interface bilayers." Thesis, University of Oxford, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711943.

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12

Blakeston, Anita Catherine. "Biomimetic lipid bilayers." Thesis, University of Leeds, 2015. http://etheses.whiterose.ac.uk/11531/.

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The aims of the collaboration project, of which this project plays a key part, are to establish a new field of “low-dimensional chemistry” in order to synthesize manipulate and characterise the components of the photosynthetic system of Rhodobacter Sphaeroides. At a fundamental level, the physical processes involved in membrane biochemistry are to be investigated. Specifically, the environment in which the light harvesting components are found, their structure and function, including proton gradient formation, diffusion mechanisms, electron transport and the molecular association between them

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13

Zhang, Tejia. "Discovery of bioactive lipids and lipid pathways in cell death and disease." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11483.

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Apoptosis is an intricately regulated cellular process required for the health and homeostasis of living systems. The mitochondrial apoptotic pathway depends on the BCL-2 family of pro- and anti-apoptotic members whose interactions regulate cell fate. BAX and BAK are key pro-apoptotic proteins required for mitochondrial permeabilization during apoptosis. While the mitochondrial death program relies heavily on its protein components, evidences support equally crucial roles for lipids and lipid metabolism in promoting or hindering apoptosis at the mitochondria. To gain insight into the inter

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14

Subramaniam, Varuni. "Preparation and Characterization of Novel Lipid and Proteolipid Membranes from Polymerizable Lipids." Diss., The University of Arizona, 2006. http://hdl.handle.net/10150/194889.

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The work described here has focused on two types of supramolecular assemblies, supported lipid bilayers (SLBs) and giant vesicles (GVs) from polymerizable lipids. SLBs are explored extensively as structural models in biophysical studies of cell membranes and biosensor coatings. With regard to implementation as biocompatible scaffoldings for receptor-based molecular devices, fluid SLBs lack chemical, thermal and mechanical stability as lipids are self-organized by weak, noncovalent forces. One possible solution is to use synthetic lipid monomers that can be polymerized to f

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15

McClinchie, Elizabeth A. "Homologs of Mammalian Lysosomal Lipase in Arabidopsis and Their Roles in Lipid Droplet Dynamics." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc1062826/.

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Lipid droplets (LDs) are organelles with many functions in cells and numerous protein interactors facilitate their biogenesis, maintenance, and turnover. The mammalian lipase responsible for LD turnover during lipophagy, LipA, has two candidate homologs in Arabidopsis: MPL1 and LIP1. One or both of these plant homologs may function in a similar manner to mammalian LipA, providing an LD breakdown pathway. To test this hypothesis, wild type (WT) Arabidopsis plants, MPL1 over-expressing (OE) mutants, and T-DNA insertion mutants of MPL1 (mpl1) and LIP1 (lip1) were examined for LD phenotypes in no

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16

Garton, Natalie Jane. "Investigation of mycobacterial lipid domains by use of fluorescent lipid probes." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244396.

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17

Saeed, Suhur. "Lipid oxidation mechanisms and lipid-protein interactions in frozen mackerel (Scomber scombrus)." Thesis, University of Surrey, 1998. http://epubs.surrey.ac.uk/843251/.

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Atlantic mackerel (Scomber scombrus) is a pelagic fish widely distributed along the Northern coast of Great Britain. The lipid content of mackerel was found to be about 13% of the total body weight and 50% of total fatty acids were eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (fatty acids which are reported to reduce the concentration of plasma triglycerides, LDL (low density lipoproteins) and cholesterol in humans and animals). The proximate analysis also showed that mackerel is a good source of protein (20% w/w). The poly unsaturated fatty acids (PUFA) are prone to oxidation du

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18

Bonzom, Pascale Marie Andree. "High resolution NMR applied to lipid analysis and lipid based drug design." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300537.

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19

Ntola, Chifundo Nyasha Michelle. "Solid lipid matrices for delivery of laundry actives and lipid membrane transport." Thesis, Durham University, 2017. http://etheses.dur.ac.uk/12027/.

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The work presented in this thesis reports the preparation and characterisation of novel solid lipid microparticle (SLM) and solid lipid nanoparticle (SLN) systems for applications in delivery of laundry actives and transport of electroactive substances into lipid membranes. The SLM and SLN systems studied are: silicone-loaded SLM, dye-loaded SLM, dual-active SLM (both silicone and dye) and ferrocene-loaded SLN (Fc-SLN). Silicones are used as fabric softeners in laundry applications and dyes are used to enhance the hue of fabrics. The incorporation of two actives into one, dual-active SLM, is a

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20

Nikolaus, Jörg. "Hemifusion and lateral lipid domain partition in lipid membranes of different complexity." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2011. http://dx.doi.org/10.18452/16437.

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Die Fusion von Membranen erfordert die Verschmelzung von zwei Phospholipiddoppel-schichten, wobei dies über dieselben Zwischenschritte abzulaufen scheint. Eine lokale Störung (‚Stalk’) stellt eine erste Verbindung der äußeren Membranhälften dar, die anschließend lateral expandiert und ein Hemifusionsdiaphragma (HD) bildet. Das Öffnen einer Fusionspore im HD führt zur vollständigen Fusion. Mittels konfokaler Mikroskopie wurde die Fusion von Giant unilamellar vesicles (GUVs) mit negativ geladenen Lipiden und transmembranen (TM) Peptiden in Anwesenheit von zweiwertigen Kationen beobachtet, wobei

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21

Kamo, Tomoari. "Lipid membrane structure modulated by nonlamellar-forming lipids and interaction with amphipathic peptide." 京都大学 (Kyoto University), 2007. http://hdl.handle.net/2433/137121.

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22

Covey, Scott D. Trigatti Bernardo L. "Carrier mediated lipid transport /." *McMaster only, 2003.

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23

Henderson, Erron James. "Lipid peroxidation by myeloperoxidase." Thesis, University of Canterbury. Zoology, 1998. http://hdl.handle.net/10092/6850.

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The oxidative modification of low density lipoprotein (LDL) is a requirement for the development of atherosclerosis. Heinecke's group has shown immunologically that myeloperoxidase (MPO) is present in human atherosclerotic lesions, both extracellularly and intracellularly (Daugherty et al., 1994). The enzyme MPO has a potent oxidising potential and is responsible for a large number of the reactants produced during the immune response (Weiss, 1989). Therefore, the neutrophil enzyme MPO has recently been implicated in in vivo LDL oxidation. A few studies exist which suggest that MPO is capable

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24

Blyth, Alison. "Lipid biomarkers in speleothems." Thesis, University of Newcastle Upon Tyne, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435638.

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25

Daulton, Emma. "Biomimetic floating lipid membranes." Thesis, University of Bath, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.675722.

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26

Sherratt, Anna Louise. "Lipid bodies in mycobacteria." Thesis, University of Leicester, 2008. http://hdl.handle.net/2381/30499.

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A survey of clinical samples revealed that LBs are a universal feature of tubercle bacilli in sputum. A number of conditions including hypoxia, Nitric Oxide (NO) exposure, pH, heat and cold shock were shown to promote LB formation in M. tuberculosis in vitro. The formation of LBs in NO exposed M. tuberculosis was shown to correlate with the level of antibiotic tolerance displayed by the population. Antibiotic tolerance was thought to be a result of transitory growth arrest; however attempts to assess the growth status of LB positive M. tuberculosis cells were unsuccessful. The morphology of LB

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27

Kilaru, Aruna. "Lipid Detection and Visualization." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/7731.

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28

Martinez, Ortega Maria Eugenia. "Lipid metal organic networks." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2009. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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29

Thorén, Klas. "Lipid-extracted bone grafts." Lund : Dept. of Orthopedics, University Hospital, Lund University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39676934.html.

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30

Darroch, Peter Ian. "Lipid phosphate phosphatases : purification and investigation of their role in cellular lipid signalling." Thesis, University of Strathclyde, 2001. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21171.

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Several isoforms of LPP have now been identified and cloned but remain to be purified. In the present study, a bacterial expression system was established and hexa- and deca-histidine epitope tagged-LPP1 and LPPla expressed in E. coli. In addition, a maltose binding protein (MBP) epitope tagged-LPP Ia was expressed in E. coli. Hexa- and deca-histidine LPP1 and LPPla, were partially purified using immobilised affinity chromatography. MBP-LPPla was expressed to higher levels than hexa- and deca-histidine LPP1 and LPPla in E. coli, most probably within insoluble inclusion bodies. In all cases, re

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31

Ding, Yuan [Verfasser]. "Lipid nanoparticles for topical delivery: solid lipid nanoparticles (SLN) & smartLipids / Yuan Ding." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1176632329/34.

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32

Borthwick, Faye. "Studies on the role of 'start' lipid trafficking proteins in macrophage lipid homeostasis." Thesis, Glasgow Caledonian University, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496152.

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Steroidogenic acute regulatory (StAR) related-lipid transfer (START) proteins (STARD1-STARD15) are suggested to play a role in cholesterol homeostasis and atherosclerosis, and are potential drug targets by virtue of their lipid binding domains. Members of the STARD1 subfamily (STARD1, STARD3) of lipid trafficking 'START' proteins can reduce macrophage lipid content and inflammatory status (STARD1; StAR), and traffic cholesterol from the endosomes (STARD3/MLN64) All of the 'START' family members were found to be expressed in human heart aorta, peripheral blood monocytes and human THP-1 monocyte

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33

Ng, Ai-Leng. "Comparisons of serum lipid levels and dietary lipid intakes of parents and children." Thesis, Virginia Tech, 1988. http://hdl.handle.net/10919/43259.

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Fifty-seven subjects from 14 families participated in a study designed to investigate similarities and differences between parents and children residing with them relative to their serum lipid levels and dietary lipid intakes. To participate, at least one of the parents needed to have a serum total cholesterol of at least 240 mg/dL. Fasting blood samples obtained from the participants were analyzed for serum total cholesterol, HDL-C, LDL-C, and VLDL-C levels. Anthropometric measurements and blood pressure readings also were taken. Dietary records, questionnaires on lifestyle, health habits,

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34

Addy, Victoria Louise. "The use of lipid hydrolases to target the lipid components of ovine skin." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711595.

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35

Veatch, Sarah Louise. "Liquid immiscibility in model bilayer lipid membranes /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/9772.

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36

Sturgeon, Raymond M. "Interplay between cations, anionic lipids, and lipid-protein interactions at the nicotinic acetylcholine receptor." Thesis, University of Ottawa (Canada), 2009. http://hdl.handle.net/10393/28070.

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Mixtures of phosphatidylcholine (PC) and phosphatidic acid (PA) are particularly effective at stabilizing a functional nicotinic acetylcholine receptor (nAChR). To test whether the ability of PA to adopt both monoanionic and dianionic states plays a role in lipid-nAChR interactions, we monitored the ionization state of PA in nAChR-reconstituted membranes. In the presence of the nAChR, PA head groups in PC/PA 3:2 membranes are stabilized in the monoanionic state. Stabilization of monoanionic PA in nAChR-reconstituted membranes accounts for some of the observed increase in membrane gel-to-liquid

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37

Prindiville, John S. "Circulating lipoproteins and tissue lipids: Effects of gemfibrozil on lipid metabolism in rainbow trout." Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28555.

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Lipids support crucial functions in teleost fish, including the production of energy; lipoproteins support the movement of lipids through the vascular system. The objective of this thesis was to determine if gemfibrozil (GEM), a mammalian PPARalpha agonist pharmaceutical, could alter the circulating lipoproteins and tissue lipid metabolism in the rainbow trout, Oncorhynchus mykiss. Injections of GEM lowered the concentration of lipoproteins and changed their size distribution, lipid and fatty acid content. These changes were associated with an increased lipoprotein lipase transcript level but

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38

Herzog, Ronny. "Novel concepts for lipid identification from shotgun mass spectra using a customized query language." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-90497.

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Lipids are the main component of semipermeable cell membranes and linked to several important physiological processes. Shotgun lipidomics relies on the direct infusion of total lipid extracts from cells, tissues or organisms into the mass spectrometer and is a powerful tool to elucidate their molecular composition. Despite the technical advances in modern mass spectrometry the currently available software underperforms in several aspects of the lipidomics pipeline. This thesis addresses these issues by presenting a new concept for lipid identification using a customized query language for mass

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39

Mateos, Diaz Eduardo. "Etude par spectroscopie infrarouge (FTIR) des interactions de la lipase pancréatique apparentée de type 2 (PLRP2) avec les phospholipides et les sels biliaires." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4763.

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La lipase pancréatique apparentée de type 2 du cobaye (GPLRP2) hydrolyse une grande variété de substrats lipidiques. Elle montre cependant une sélectivité selon l’organisation supramoléculaire du substrat et la présence de surfactants comme les sels biliaires (NaTDC). Nous avons utilisé la spectroscopie infrarouge (FTIR) pour étudier les interactions entres les phospholipides (DPPC), les surfactants et la GPLRP2 dans des conditions expérimentales proches de celles du tractus digestif. Pour étudier l’étape d’adsorption indépendamment de l’hydrolyse, un variant inactif de GPLRP2 (S152G) a été pr

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Petkevicius, Kasparas. "The role of macrophage intracellular lipid partitioning in glucose and lipid homeostasis during obesity." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/285429.

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Obesity-associated metabolic disorders are amongst the most prevalent causes of death worldwide. Understanding how obesity leads to the development of the Metabolic Syndrome (MetS) and cardiovascular disease (CVD) will enable the development of novel therapies that dissociate obesity from its cardiometabolic complications. Our laboratory views the functional capacity of white adipose tissue (WAT), the organ designed for safe lipid storage, as a key factor in the development of MetS and CVD. At a genetically-defined stage of the aberrant WAT expansion that occurs during obesity, adipocytes unde

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41

Cheong, Fei Ying. "Regulation of lipid signaling at the Golgi by the lipid phosphatases hSAC1 and OCRL1." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:16-opus-71011.

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Turenne, Eric D. "Lipid Mobilization In Exercising Salmonids." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37075.

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Animals rely on lipids as a major fuel for endurance exercise because they pack more joules per gram than any other fuel. However, in contrast to mammals, information on how the mobilization of lipids from endogenous stores is managed to meet the needs of energy metabolism in swimming fish is sparse. Information on in vivo rates of lipid mobilization in swimming fish has been limited to relatively low exercise intensities and has only been investigated in a single species. Therefore, the goal of my thesis was to address this paucity of information by quantifying lipolytic rate in rainbow trout

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Harczy, Martha. "Lipid mediators in lung anaphylaxis." Mémoire, Université de Sherbrooke, 1988. http://hdl.handle.net/11143/11716.

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Abstract: Arachidonic acid and PAF are released from the lungs during anaphyIaxis. The aim of this study is to describe the kinetics of the release of eicosanoids and to observe the effects of selected ihhibitors and a PAF antagonist on their release. Isolated lungs of previously sensitized animals were perfused via the pulmonary artery and challenged with ovalbumin. Prostaglandin E21 throraboxane B2, 6-keto prostaglandin F1? levels were determined in aliquots of effluents with radioimmunoassay and/or enzyme immunoassay techniques whereas leukotrienes B4 and D4 were measured by reverse-phase h

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44

Shilton, Catherine Margaret. "Corneal lipid deposition in anurans." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0020/NQ55639.pdf.

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Hafez, Ismail Mahmoud. "Lipid polymorphism and intracellular delivery." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0021/NQ56555.pdf.

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46

Raggers, René John. "Lipid translocation by multidrug transporters." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2001. http://dare.uva.nl/document/60218.

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47

Derrien, Thomas. "Gold nanoparticle-lipid bilayer interactions." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86727.

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The interactions of ligand-capped gold nanoparticles with lipid bilayers are investigated. The properties determining the mechanism of nanoparticle interaction using synthetic membrane models are explored. First, a specific interaction, incorporation of nanoparticles into the bilayers, is examined using novel imaging and nanoparticle synthesis techniques. Mixed ligand capped gold nanoparticles are synthesized with assorted ligand arrangements in order to relate ligand composition and structure to interaction mechanism using a dye leakage assay. Finally, in vivo experiments are conducted using

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Khatchadourian, Armen. "Lipid droplets under stressful conditions." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116901.

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Lipid droplets (LDs) are phylogenetically conserved and ubiquitous organelles with many cellular functions. In the last two decades, our understanding of LD biology and of their roles in physiological processes has increased dramatically. In addition, increasing evidence suggests that LDs are highly involved in inflammatory processes, and in metabolic disorders such as type 2 diabetes mellitus (T2DM). Despite such advancement, many aspects of LD biology and of their roles in health and disease remain unknown.The core of LDs is highly enriched with neutral lipids and these can be mobilized to p

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McEwan, S. J. "Studies on skeletal lipid metabolism." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233475.

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Deol, Sundeep Singh. "Analysis of lipid-protein interactions." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424760.

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