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Artykuły w czasopismach na temat "Liver Copper"

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Kruitwagen, Hedwig S., Hille Fieten, and Louis C. Penning. "Towards Bioengineered Liver Stem Cell Transplantation Studies in a Preclinical Dog Model for Inherited Copper Toxicosis." Bioengineering 6, no. 4 (2019): 88. http://dx.doi.org/10.3390/bioengineering6040088.

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Wilson Disease is a rare autosomal recessive liver disorder in humans. Although its clinical presentation and age of onset are highly variable, hallmarks include signs of liver disease, neurological features and so-called Kayser-Fleischer rings in the eyes of the patient. Hepatic copper accumulation leads to liver disease and eventually to liver cirrhosis. Treatment options include life-long copper chelation therapy and/or decrease in copper intake. Eventually liver transplantations are indicated. Although clinical outcome of liver transplantations is favorable, the lack of suitable donor live
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GOONERATNE, S. R., and D. A. CHRISTENSEN. "A SURVEY OF MATERNAL COPPER STATUS AND FETAL TISSUE COPPER CONCENTRATIONS IN SASKATCHEWAN BOVINE." Canadian Journal of Animal Science 69, no. 1 (1989): 141–50. http://dx.doi.org/10.4141/cjas89-017.

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Copper (Cu) status of cattle raised in different soil zones of Saskatchewan was examined with emphasis on the relation between liver Cu concentration in pregnant cows, stage of pregnancy and fetal liver Cu status. Whole fetuses and livers from adult animals were obtained during routine slaughter operation at a local packing plant. Twenty percent of steers, 54% of pregnant cows, 52% of heifers and 77% of nonpregnant cows had liver Cu levels less than 25 mg kg−1 dry matter (DM). Hypocuprosis was most marked in cattle originating from northern regions of Saskatchewan. Fetal liver Cu concentration
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Muchenditsi, Abigael, Haojun Yang, James P. Hamilton, et al. "Targeted inactivation of copper transporter Atp7b in hepatocytes causes liver steatosis and obesity in mice." American Journal of Physiology-Gastrointestinal and Liver Physiology 313, no. 1 (2017): G39—G49. http://dx.doi.org/10.1152/ajpgi.00312.2016.

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Copper-transporting ATPase 2 (ATP7B) is essential for mammalian copper homeostasis. Mutations in ATP7B result in copper accumulation, especially in the liver, and cause Wilson disease (WD). The major role of hepatocytes in WD pathology is firmly established. It is less certain whether the excess Cu in hepatocytes is solely responsible for development of WD. To address this issue, we generated a mouse strain for Cre-mediated deletion of Atp7b and inactivated Atp7b selectively in hepatocytes. Atp7bΔHep mice accumulate copper in the liver, have elevated urinary copper, and lack holoceruloplasmin
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Schultheiss, Patricia C., Cathy L. Bedwell, Dwayne W. Hamar, and Martin J. Fettman. "Canine Liver Iron, Copper, and Zinc Concentrations and Association with Histologic Lesions." Journal of Veterinary Diagnostic Investigation 14, no. 5 (2002): 396–402. http://dx.doi.org/10.1177/104063870201400506.

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Concentrations of iron, copper, and zinc were measured in livers of 95 dogs that were suspected of having liver disease. Iron concentrations ranged from 177 to 7,680 ppm (dry weight basis); 54 dogs had iron concentrations greater than the normal concentration of 1,200 ppm. Iron stores were present in Kupffer cells and macrophages but not hepatocytes. The dogs did not have lesions of hemochromatosis. Dogs with high liver iron tended to have high liver copper and inflammatory lesions. High liver copper concentrations usually were associated with hepatocellular necrosis and fibrosis. High liver z
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Sabullah, Mohd Khalizan, Fisal Ahmad, Azlan Jualang Gansau, and Mohd Rosni Sulaiman. "A one dimensional PAGE studies on <i>Puntius javanicus</i> liver proteome affected by copper toxicity." Bioremediation Science and Technology Research 3, no. 2 (2015): 26–29. http://dx.doi.org/10.54987/bstr.v3i2.297.

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Observations on the effects of copper on the liver proteome of Puntius javanicus based on the one dimensional PAGE was carried out. The liver was dissected from each fish, which was separately treated with different concentrations of copper sulfate ranging from 0.1 to 5.0 mg/L. The livers were extracted and one dimensional PAGE was performed under nonreducing (native) and reducing (SDS)-PAGE. Several bands were resolved in the native PAGE with probable candidates for the effect of copper observed showing an increased in the expression and downregulation strongly associated with increasing cop
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Wu, Xiaoyan, Hsiaotzu Chien, Monique E. van Wolferen, Hedwig S. Kruitwagen, Loes A. Oosterhoff, and Louis C. Penning. "Reduced FXR Target Gene Expression in Copper-Laden Livers of COMMD1-Deficient Dogs." Veterinary Sciences 6, no. 4 (2019): 78. http://dx.doi.org/10.3390/vetsci6040078.

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Wilson’s disease (WD), an autosomal recessive disorder, results in copper accumulation in the liver as a consequence of mutations in the gene ATPase copper transporting beta (ATP7B). The disease is characterized by chronic hepatitis, eventually resulting in liver cirrhosis. Recent studies have shown that dysregulation of nuclear receptors (NR) by high hepatic copper levels is an important event in the pathogenesis of liver disease in WD. Intracellular trafficking of ATP7B is mediated by COMMD1 and, in Bedlington terriers, a mutation in the COMMD1 gene results in high hepatic copper levels. Her
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Thornburg, L. P., M. Beissenherz, M. Dolan, and M. F. Raisbeck. "Histochemical Demonstration of Copper and Copper-Associated Protein in the Canine Liver." Veterinary Pathology 22, no. 4 (1985): 327–32. http://dx.doi.org/10.1177/030098588502200405.

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Three different histochemical methods for copper detection were compared. Atomic absorption analysis was used to substantiate the tissue stains. There was good correlation between rhodanine staining and rubeanic acid-stained tissue sections. The orcein reaction for copper-associated protein did not consistently correlate with the methods demonstrating copper. Prolonged staining (72 hours) with rubeanic acid more consistently and clearly detected increased copper in canine livers than did staining with rhodanine. Seventy-two hour staining with rubeanic acid is the method of choice for histochem
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Gabriel, O. Wordu, and Obinna Echem P. "EFFECTS OF ROXARSONE ON COPPER UTILIZATION BY CHICK." Continental J. Food Science and Technology 2 (July 25, 2008): 1–5. https://doi.org/10.5281/zenodo.834639.

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Experiment was conducted to examine the effect of dietary roxarsone (3-nitro-4-hydroxyphemylarsonic acid) on Cu utilization by chick. A fortified corn-soybean meal diet was fed to the chick. Roxarsone dramatically reduced liver cu concentration at all levels of supplemental Cu fed. The level of roxarsone commonly fed, 50 mg/kg diet, resulted in a two-to-four fold depression in liver Cu concentration in chick. The effects of roxarsone on weight gain were more perplexity. In the chick, the diets containing 100 and 250 mg Cu/kg depressed growth in the presence, but not in the absence, of 50mg/kg
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Yamkate, Punyamanee, Randi M. Gold, David C. Twedt, Jan S. Suchodolski, Joerg M. Steiner, and Jonathan A. Lidbury. "Assessment of the intracellular distribution of copper in liver specimens from cats." PLOS ONE 17, no. 2 (2022): e0264003. http://dx.doi.org/10.1371/journal.pone.0264003.

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The intracellular distribution of copper in the liver has been investigated in dogs and humans. However, this has not been reported in cats. This study aimed to assess the intracellular copper distribution in liver specimens from cats with a range of hepatic copper concentrations. Twenty-nine frozen liver specimens from cats were included. Each liver specimen was divided into two pieces for overall copper quantification and tissue fractionation. The copper concentrations in liver specimens and liver fractions were measured by flame atomic absorption spectroscopy. Five specimens had copper conc
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IVAN, M., J. G. PROULX, R. MORALES, H. C. V. CODAGNONE, and M. DE S. DAYRELL. "COPPER ACCUMULATION IN THE LIVER OF SHEEP AND CATTLE FED DIETS SUPPLEMENTED WITH COPPER SULFATE OR COPPER CHLORIDE." Canadian Journal of Animal Science 70, no. 2 (1990): 727–30. http://dx.doi.org/10.4141/cjas90-089.

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Six groups of 12 pregnant cows were fed barley or grass silage with or without copper sulfate or copper chloride supplements (16 or 14 mg copper kg−1 dry matter (DM)). In addition, five groups of 10 lambs were fed diets supplemented with 5 or 10 mg Cu kg−1 DM as salts of sulfate or chloride. The two Cu salts produced equal increases in the concentration of Cu in the livers of both sheep and cattle. Key words: Sheep, cattle, liver, copper sulfate, copper chloride
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Rozprawy doktorskie na temat "Liver Copper"

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SAKAMOTO, NOBUO, HISAO HAYASHI, TOMOYUKI HIGUCHI, AKIRA YAGI, and NAOKI HISHIDA. "Cuproproteins of Hepatocyte Lysosomes in Normal and Fatty Liver." Nagoya University School of Medicine, 1993. http://hdl.handle.net/2237/17538.

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Davis, William. "Synthesis and secretion of caeruloplasmin in normal and copper toxic liver." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283963.

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Leighton, Margaret Janet. "The accumulation and subcellular localization of copper in the liver of foetal deer." Thesis, Royal Veterinary College (University of London), 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.519519.

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Hassel, Craig Alan. "LIPOPROTEIN RECEPTORS IN COPPER-DEFICIENT RATS: IN VITRO BINDING OF HIGH DENSITY LIPOPROTEIN SUBFRACTIONS TO LIVER MEMBRANES." Diss., The University of Arizona, 1986. http://hdl.handle.net/10150/183955.

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Three studies were conducted to determine whether the elevated plasma and HDL cholesterol levels observed in copper-deficient rats could be explained by the interaction of ¹²⁵I-HDL subfractions with liver membrane preparations in vitro. Rats from all studies were randomly divided into two dietary treatments, copper-deficient and adequate (0.7 mg and 8.0 mg Cu/kg diet, respectively). Deionized water and diet were provided ad libitum. After eight weeks, rats were exsanguinated, membranes prepared from livers, and plasma high density lipoproteins (HDL) isolated by ultracentrifugation and agarose
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Zhang, Jin 1960. "The influence of copper deficiency on the binding and uptake of high-density lipoprotein by rat hepatic parenchymal cells." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276935.

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This study was designed to examine the influence of Cu deficiency on the binding, uptake, and degradation of apolipoprotein E-free high density lipoproteins (apo E-free HDL) in cultured rat hepatic parenchymal cells. The binding of apo E-free HDL during time course studies was slightly but significantly increased in cells derived from Cu-deficient rats. In saturation studies, the amount of surface-bound apo E-free HDL appeared to be saturable, although no difference was observed between Cu-deficient and adequate animals. The amount of total and specific cell-associated uptake of apo E-free HDL
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Minervino, Antonio Humberto Hamad. "Estudo comparativo da susceptibilidade de bovinos e bufalinos à intoxicação cúprica acumulativa." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-25042007-100336/.

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O presente trabalho objetivou avaliar comparativamente a susceptibilidade dos bufalinos e bovinos à intoxicação cúprica acumulativa, por meio do fornecimento de quantidades crescentes de cobre, analisando variáveis clínicas, sangüíneas e os teores de cobre hepático. Com tal objetivo, foram utilizados 20 ruminantes, 10 bovinos (mestiços) e 10 búfalos (raça Murrah) jovens, aleatoriamente distribuídos em seis animais de cada espécie nos grupos que receberam cobre (BOV Cu e BUF Cu) e quatro animais nos grupos controle (BOV e BUF). Diariamente, os grupos BOV Cu e BUF Cu receberam por meio de fistu
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黃業發 and Ip-fat Wong. "Effects of D-penicillamine on the alterations in copper and zinc disposition in liver tissues following endotoxin treatment ingalactosamine-sensitized mice." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31969859.

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Wong, Ip-fat. "Effects of D-penicillamine on the alterations in copper and zinc disposition in liver tissues following endotoxin treatment in galactosamine-sensitized mice." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22032460.

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Al-Othman, Abdullah Abdulrahman. "Influence of copper deficiency on liver morphology, aortic integrity, plasma lipoprotein and hepatic lipid profiles, and hepatic fatty acid synthesis in vivo." Diss., The University of Arizona, 1992. http://hdl.handle.net/10150/185745.

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Three studies were designed to investigate the influence of dietary copper (Cu) on liver morphology, aortic integrity, lipid composition of lipoproteins, fatty acid profile of hepatic lipids, as well as in vivo hepatic fatty acid synthesis. Animals were randomly assigned to two dietary Cu treatments (deficient and adequate). Reductions in body weight, liver Cu content, and hematocrit, as well as elevations in liver weight and plasma volume were observed in animals fed Cu-deficient diet. Electron micrographs suggest that the Cu-deficient liver parenchymal cells contain a higher number of mitoch
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Lentz, Daniela. "Deficiência de cobre como causa de enfermidade sazonal em bovinos no Estado de Santa Catarina." Universidade do Estado de Santa Catarina, 2012. http://tede.udesc.br/handle/handle/801.

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Made available in DSpace on 2016-12-08T16:24:04Z (GMT). No. of bitstreams: 1 PGCA12MA038.pdf: 2912659 bytes, checksum: a707fa201b75de04c816893aa22d474d (MD5) Previous issue date: 2012-06-15<br>It has been described the epidemiological, clinical signs and lesions of a disease of cattle characterized by seasonal occurrence of outbreaks of diarrhea, chronic fever, responsive to treatment with copper sulfate. The disease occurs on properties with steeply sloping topography of the different regions of the state of Santa Catarina, with greater frequency in the west Highlands and Serra, in the mont
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Książki na temat "Liver Copper"

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Hillis, Tracey L. Metal burdens in the liver and kidney of beaver (Castor canadensis) residing near copper/nickel smelter in Sudbury, Ontario. Laurentian University, Department of Biology, 1987.

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Keshav, Satish, and Palak Trivedi. Genetic liver disease. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0214.

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This chapter discusses three of the major inherited forms of liver disease (all autosomal recessive): hereditary haemochromatosis, Wilson’s disease, and alpha-1-antitrypsin deficiency. Hereditary haemochromatosis is characterized by excessive absorption of dietary iron, with a pathological increase in total body iron that accumulates in tissues and organs, disrupting their function. Wilson’s disease (hepatolenticular degeneration) is an autosomal recessive genetic disorder in which copper accumulates in tissues. Alpha-1-antitrypsin deficiency is characterized by reduced circulating levels of a
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Beattie, R. Mark, Anil Dhawan, and John W.L. Puntis. Wilson's disease. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569862.003.0056.

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Clinical features 412Diagnosis 413Management 414Indications for liver transplantation 415• Wilson's disease (WD) is an autosomal disorder of copper metabolism. The gene ATP7B codes for a copper carrier which both exports copper from hepatocyte to bile, and enables caeruloplasmin synthesis.• WD occurs worldwide with reported incidences of 5–30 per million population. WD may present with almost any variety of liver disease in the age group 3–12 years, with psychiatric and/or neurological disease in adolescence or young adults, with combined hepatic and neurological problems, or less commonly wit
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Fox, Susan H. Seizures and Shakes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190607555.003.0017.

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Wilson’s disease is an autosomal recessive, treatable heredodegenerative disorder characterized by excessive deposition of copper in the liver, brain, and other tissues including the kidneys, pancreas, and joints. Early recognition of the disorder, which can present with a variety of movement disorders and neuropsychiatric phenomena, is critical to avoid irreversible end organ damage through the initiation of copper chelating agents. Diagnosis relies first on demonstrating evidence of brain iron deposition on magnetic resonance imaging of brain and elevated urinary copper excretion in the appr
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Live - Throwing Copper*. Hal Leonard Corporation, 1996.

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Wilson’s Disease. Exon Publications, 2024. http://dx.doi.org/10.36255/wilsons-disease.

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Wilson’s Disease is a rare genetic disorder that disrupts the body’s ability to eliminate excess copper, leading to harmful accumulations in organs such as the liver, brain, and eyes. This article serves as a comprehensive guide, providing clear and detailed information for patients, families, and caregivers. It begins by explaining what Wilson’s Disease is and the role of the ATP7B gene in causing the condition. The article explores its prevalence, types, and inheritance patterns, highlighting the importance of genetic testing and family screening. The article discusses the wide range of symp
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Scheyder, Ernest. War Below: Lithium, Copper, and the Global Battle to Power Our Lives. Atria Books, 2024.

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Scheyder, Ernest. War Below: Lithium, Copper, and the Global Battle to Power Our Lives. Princeton University Press, 2024.

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Scheyder, Ernest. War Below: Lithium, Copper, and the Global Battle to Power Our Lives. Atria Books, 2024.

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Scheyder, Ernest. War Below: Lithium, Copper, and the Global Battle to Power Our Lives. Princeton University Press, 2024.

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Części książek na temat "Liver Copper"

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McArdle, Harry J., Michelle J. Bingham, Karl Summer, and T. J. Ong. "Cu Metabolism in the Liver." In Copper Transport and Its Disorders. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4859-1_3.

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Mylroie, Augusta A., Constance Umbles, and Joseph Kyle. "Superoxide Dismutase Activity of Heart and Liver Tissue from Copper Deficient Rats." In Biology of Copper Complexes. Humana Press, 1987. http://dx.doi.org/10.1007/978-1-4612-4584-1_41.

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Müller, Thomas, and Stuart Tanner. "Disorders of Copper Metabolism." In Diseases of the Liver and Biliary System in Children. John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119046936.ch20.

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Tanner, Stuart. "Disorders of Copper Metabolism." In Diseases of the Liver and Biliary System in Children. Wiley-Blackwell, 2009. http://dx.doi.org/10.1002/9781444300536.ch14.

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Tanner, M. S. "Copper Related Liver Disease in Young Children." In Metals and Genetics. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4723-5_24.

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Elmes, M. E., J. P. Clarkson, B. Jasani, and N. J. Mahy. "Metallothionein and Copper in Human Liver — A Histopathological Study." In Trace Elements in Man and Animals 6. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0723-5_263.

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Mercer, J. F. B., J. Smith, A. Grimes, J. McC Howell, P. Gill, and D. M. Danks. "Zinc, Copper and Metallothionein mRNA in Sheep Liver during Development." In Trace Elements in Man and Animals 6. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0723-5_249.

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Klein, Dominik, Josef Lichtmannegger, Ulrich Heinzmann, Josef Müller-Höcker, and Karl H. Summer. "Fate of copper and metallothionein in the liver of LEC rats." In Metallothionein IV. Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-8847-9_58.

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Sawa, A., and K. Okita. "The Role of Copper and Zinc as Pathogenic Factors in Liver Disease." In Trace Elements in Clinical Medicine. Springer Japan, 1990. http://dx.doi.org/10.1007/978-4-431-68120-5_10.

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Suzuki, Kazuo T., Ming Rui, Jun-ichi Ueda, and Toshihiko Ozawa. "Roles of metallothionein in the cytotoxicity of copper in the liver of LEC rats." In Metallothionein IV. Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-8847-9_57.

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Streszczenia konferencji na temat "Liver Copper"

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McConnell, Stanley B. "Chemical Treatment of Thiourea in Acidic Cleaning Wastes." In CORROSION 1990. NACE International, 1990. https://doi.org/10.5006/c1990-90149.

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Abstract The disposal of spent-chemical cleaning solutions and chemicals has recently become more difficult and expensive, because of new environmental regulatory guidelines. Increasing public awareness makes it clear that new and more effective treatment methods are needed which completely eliminate or detoxify hazardous substances. The use of thiourea in combination with inhibited acid is well-established technology for the chemical removal of iron and copper scales from industrial equipment. However, thiourea is a suspected carcinogen that has caused cancer (skin, thyroid and liver) in labo
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Michel, James H., Carol A. Powell, and Harold T. Michels. "An Assessment of the Biofouling Resistance and Copper Release Rate of 90-10 Copper-Nickel Alloy." In CORROSION 2011. NACE International, 2011. https://doi.org/10.5006/c2011-11352.

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Abstract 90-10 copper-nickel is one of the few engineering alloys available which offer both high resistance to seawater corrosion and biofouling. The alloy is not immune to microfouling but colonization of macrofouling is much restricted. The mechanism is not fully understood and is thought to be at least partially linked to copper ion release from the complex protective surface film. There may also be an effect of the nature of the surface film itself. There are no suitable standards available to assess copper release from solid alloys but ASTM* D64421, Standard Test Method for Copper Releas
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Abed, Khalil, Pankaj Panchal, and Amish Gandhi. "Evaluation of Impressed Current Cathodically Protected API 650 Tank Bottoms in the Presence of Vapor Phase Corrosion Inhibitor." In CORROSION 2016. NACE International, 2016. https://doi.org/10.5006/c2016-07600.

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Abstract This work aims to assess the effectiveness of amine carboxylate based Vapor Phase Corrosion Inhibitor (VPCI) on the protection of storage tank bottoms against soil-side corrosion, as standalone and in combination with Impressed Current Cathodic Protection (ICCP) system. It also attempts to determine the effect of VPCI on instant-off potential. Lab-scale tanks simulating the environment of single bottom storage tank sitting on washed sand with High-density polyethylene (HDPE) liner and ICCP system were considered. Corrosion rate for each tank was monitored using Electrical Resistance (
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He, Jie, Lizheng (Leo) Zhang, Rachel Zhou, Adan Herrera, David Ball, and Peter Ellis. "Evaluation of Corrosion and EAC Susceptibilities of Materials Used for Wireline Downhole Equipment in HPHT Sour Environments." In CORROSION 2018. NACE International, 2018. https://doi.org/10.5006/c2018-10688.

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Abstract Historically, the testing of sour corrosion and environmental-assisted cracking (EAC) in the oil and gas industry has focused on oil country tubular goods (OCTG) with design lives of tens of thousands of hours, while wireline and wireline tools are typically exposed to sour conditions for a few hundred hours per year at most. The existing corrosion/EAC information related to wireline materials is either overly conservative or inadequate, which significantly reduces the work scope of a great number of engineering materials that could potentially be used in wireline applications. To ove
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Opanike, Oyetunde, Olugbenga A. Omotosho, Emmanuel O. Akindele, and Omolola O. Yusuf. "Hepatocellular Effect of Copper Poisoning on the Liver and Kidney of Albino Rats (<i>Rattus norvicus</i>)." In 2023 International Conference on Sustainable Engineering and Materials Development. Trans Tech Publications Ltd, 2024. http://dx.doi.org/10.4028/p-vzg5cj.

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Copper and its salt are remarkably non-toxic to mammalian tissue. It is possible to ingest a large number of soluble copper salts such as copper sulphide to produce intoxication, nausea, vomiting, diarrhoea, and abdominal cramp. Copper salts are widely employed in agriculture and veterinary practice. Copper is an essential trace element in life and is a component of several metalloenzymes and other proteins such as cytochrome oxidase, heamocyanin, lysin oxidase, ascorbate oxidase and amine oxidase. When copper is present in the body above a particular dosage of greater than 100ppm in rats, it
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Gottlieb, A., L. Devine, A. Canbay, and S. Lutsenko. "THE LIVER COPPER STATUS ALTERS THE DEVELOPMENT OF STEATOSIS IN MICE." In 37. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0040-1722022.

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Gottlieb, A., A. Muchenditsi, and S. Lutsenko. "The liver copper status alters the development of steatosis in mice." In DGVS Digital: BEST OF DGVS. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1716162.

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Ala, Aftab, Tao Liang, Haiting Zhang, et al. "P02 Development and validation of a Novel ICP-MS method to quantify different copper species in human plasma from patients with wilson disease." In Abstracts of the British Association for the Study of the Liver Annual Meeting, 20–23 September 2022. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2022. http://dx.doi.org/10.1136/gutjnl-2022-basl.53.

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Zhou, Chuannong, Xuyan Song, Jinsheng Deng, et al. "Photodynamic effect of copper-vapor pumped-dye laser, He-Ne laser, and noncoherent red light to the liver in normal mice." In International Conference on Photodynamic Therapy and Laser Medicine, edited by Junheng Li. SPIE, 1993. http://dx.doi.org/10.1117/12.137015.

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Grossmann, Kenneth F., Mary Brittain Blankenship, Wallace Akerley, et al. "Abstract 1308: A phase I clinical study investigating disulfiram and copper gluconate in patients with advanced treatment-refractory solid tumors involving the liver." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-1308.

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Raporty organizacyjne na temat "Liver Copper"

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Ensley, Steve M., Gary Osweiler, Garland R. Dahlke, M. Peter Hoffman, and Wayne B. Roush. Post Mortem Copper Concentrations in the Liver of Feedlot Steers Fed Condensed Corn Distillers Solubles. Iowa State University, 2010. http://dx.doi.org/10.31274/ans_air-180814-583.

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Wüthrich, Annik. Amon, dieu de la ville, dans le chapitre 23 du Livre des Morts. Verlag der Österreichischen Akademie der Wissenschaften, 2021. http://dx.doi.org/10.1553/erc_stg_757951_a.wuetrich_amon_dieu_de_la_ville_dans_le_chapitre_23_du_livre_des_morts.

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Book of the Dead spell 23 aimed to allow the deceased to recover the use of his mouth: therefore, the deceased invokes, among other deities, the “god of the city” as his personal god. However, some copies of the Book of the Dead from the 26th dynasty onwards replace or add to this expression the name of the god Amon. All these papyri clearly or supposedly come from Thebes based on prosopographical and onomastic criteria. This article lists hence these different attestations, seeking to explain this phenomenon, to examine if it extends to other Egyptian cities and to investigate the concept of
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Wüthrich, Annik. Amon, dieu de la ville, dans le chapitre 23 du Livre des Morts. Verlag der Österreichischen Akademie der Wissenschaften, 2021. http://dx.doi.org/10.1553/erc_stg_757951_a.wuethrich_amon_dieu_de_la_ville_dans_le_chapitre_23_du_livre_des_morts.

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Book of the Dead spell 23 aimed to allow the deceased to recover the use of his mouth: therefore, the deceased invokes, among other deities, the “god of the city” as his personal god. However, some copies of the Book of the Dead from the 26th dynasty onwards replace or add to this expression the name of the god Amon. All these papyri clearly or supposedly come from Thebes based on prosopographical and onomastic criteria. This article lists hence these different attestations, seeking to explain this phenomenon, to examine if it extends to other Egyptian cities and to investigate the concept of
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Tawfik, Aly, Deify Law, Juris Grasis, Joseph Oldham, and Moe Salem. COVID-19 Public Transportation Air Circulation and Virus Mitigation Study. Mineta Transportation Institute, 2022. http://dx.doi.org/10.31979/mti.2021.2036.

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COVID-19 may have forever changed our world. Given the limited space and air circulation, potential infections on public transportation could be concerningly high. Accordingly, this study has two objectives: (1) to understand air circulation patterns inside the cabins of buses; and (2) to test the impact of different technologies in mitigating viruses from the air and on surfaces inside bus cabins. For the first objective, different devices, metrics and experiments (including colored smoke; videotaping; anemometers; pressure differentials; particle counts; and 3D numerical simulation models) w
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Tawfik, Aly, Deify Law, Juris Grasis, Joseph Oldham, and Moe Salem. COVID-19 Public Transportation Air Circulation and Virus Mitigation Study. Mineta Transportation Institute, 2022. http://dx.doi.org/10.31979/mti.2022.2036.

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COVID-19 may have forever changed our world. Given the limited space and air circulation, potential infections on public transportation could be concerningly high. Accordingly, this study has two objectives: (1) to understand air circulation patterns inside the cabins of buses; and (2) to test the impact of different technologies in mitigating viruses from the air and on surfaces inside bus cabins. For the first objective, different devices, metrics and experiments (including colored smoke; videotaping; anemometers; pressure differentials; particle counts; and 3D numerical simulation models) w
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Catton, Theodore, and Krahe Diane. The Shaping of a Natural and Industrial Landscape: Whiskeytown National Recreation Area Historic Resource Study. U.S. Department of the Interior, National Park Service, 2025. https://doi.org/10.36967/2313935.

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The history of Whiskeytown is primarily a history that centers around a series of resource-extraction-based human occupations. In pre-contact times the place was occupied by the Wintu and the vital resource that they exploited was salmon. In 1849, the vital resource became gold. Later it was copper. Then it was timber in the forest. And then it was water, which falls on the mountains as rain and snow and is so vital to the agriculture and population that is concentrated in the thirsty valley below. Today the vital resource is not just the mountain water itself but all the recreation that occur
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ตั้งกิจวานิชย์, พิสิฐ, อัญชลี อวิหิงสานนท์, วรพจน์ ทรัพย์ศิริสวัสดิ์ та ін. การศึกษาธรรมชาติการดำเนินโรคของการติดเชื้อไวรัสตับอักเสบซี ความสำคัญทางคลินิคปัจจัยที่เกี่ยวข้องในการรักษาการตอบสนองต่อการรักษา และผลข้างเคียงในผู้ติดเชื้อเอชไอวีที่มีการติดเชื้อไวรัสตับอักเสบซี. จุฬาลงกรณ์มหาวิทยาลัย, 2015. https://doi.org/10.58837/chula.res.2015.24.

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การศึกษานี้เป็นแบบไปข้างหน้าในผู้ป่วยที่ติดเชื้อเอชไอวีร่วมกับการติดเชื้อไวรัสตับอักเสบซีในพื้นที่กรุงเทพมหานคร ประเทศไทย โดยมีการตรวจสายพันธุ์ของไวรัสตับอักเสบซี ปริมาณไวรัสตับอักเสบซีในเลือด ยีน IL-288 และการเกิดพังผืดในตับด้วยเครื่องไฟโบรสแกน และได้แบ่งระยะของพังผืดในตับได้ดังนี้ ระยะแรก (Metavir F0-F1) เป็นระยะที่มีค่า stiffness น้อยกว่าหรือเท่ากับ 7.1 kPa ระยะที่ 2 หรือระยะปานกลาง (F2) เป็นระยะที่มีค่า stiffness ระหว่าง 7.2-9.4 kPa ระยะที่ 3 หรือระยะรุนแรง (F3) เป็นระยะที่มีค่า stiffness ระหว่าง 9.5-14 kPa และระยะสุดท้าย (F4) หรือ โรคตับแข็งที่มีค่า stiffness มากกว่า 14 kPa การตรวจประเมิน
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Tafere, Yisak, Karinten Nashipai, and Vidya Diwakar. Responding to Polycrisis in Ethiopia and Kenya. Institute of Development Studies, 2023. http://dx.doi.org/10.19088/cpan.2023.007.

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The spread of Covid-19 was layered on to various intersecting crises (‘polycrisis’), worsening people’s lives and weakening governments’ responses to the pandemic. Many responses to multiple crises focus on single hazards. This brief highlights effective responses to Covid-19, drought and conflict from Kenya and Ethiopia, which may offer lessons for future policy and programming that equitably address multiple crises. It focuses on two examples of how governments and local actors have sought to strengthen people’s ability to cope with multiple crises: through collaboration at different levels
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Bourgaux, Camille, and Anni-Yasmin Turhan. Temporal Query Answering in DL-Lite over Inconsistent Data. Technische Universität Dresden, 2017. http://dx.doi.org/10.25368/2022.236.

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In ontology-based systems that process data stemming from different sources and that is received over time, as in context-aware systems, reasoning needs to cope with the temporal dimension and should be resilient against inconsistencies in the data. Motivated by such settings, this paper addresses the problem of handling inconsistent data in a temporal version of ontology-based query answering. We consider a recently proposed temporal query language that combines conjunctive queries with operators of propositional linear temporal logic and extend to this setting three inconsistency-tolerant se
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Näslund-Hadley, Emma, Michelle Koussa, and Juan Manuel Hernández. Skills for Life: Stress and Brain Development in Early Childhood. Inter-American Development Bank, 2021. http://dx.doi.org/10.18235/0003205.

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Learning to cope with disappointments and overcoming obstacles is part of growing up. By conquering some challenges, children develop resilience. Such normal stressors may include initiating a new activity or separation from parents during preschool hours. However, when the challenges in early childhood are intensified by important stressors happening outside their own lives, they may start to worry about the safety of themselves and their families. This may cause chronic stress, which interferes with their emotional, cognitive, and social development. In developing country contexts, it is esp
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