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1

Li, Shangxiao. "Bioactive compounds from New Zealand marine organisms." Thesis, University of Canterbury. Chemistry, 1988. http://hdl.handle.net/10092/7314.

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Primary screening of recent collections from the sea around New Zealand revealed a wide range of bioactivities, including antitumour, antiviral and anti-HIV activities. Seven marine organisms, including sponges and an ascidian, were examined to identify the active compounds responsible for these three type of biological activities. A chemical screening protocol was established for the dereplication and prioritization of antiviral natural product extracts, which was also applied to extracts with other bioactivities. A recent modification included HPLC analysis of the eluates from solid phase e
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Pinheiro, Angela Maria de Marques Lopes e. Ferreira. "" Study of Bioactive Compounds of Marine-Derived Fungi"." Master's thesis, Instituto de Ciências Biomédicas Abel Salazar, 2010. http://hdl.handle.net/10216/62177.

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Pinheiro, Angela Maria de Marques Lopes e. Ferreira. "" Study of Bioactive Compounds of Marine-Derived Fungi"." Dissertação, Instituto de Ciências Biomédicas Abel Salazar, 2010. http://hdl.handle.net/10216/62177.

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Azevedo, Vítor Manuel Madureira. "Lipidomic study of the red marine macroalgae as source of bioactive compounds." Master's thesis, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/17513.

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Mestrado em Mestre em Bioquímica, ramo da Bioquímica Clínica<br>Marine macroalgae, or seaweeds, have gained an increased interest in recent times for the use in various biotechnological applications, due to the added-value of their chemical constituents. Among them, glycolipids and phospholipids display several commercial applications in a wide spectrum of industries, such as food, pharmaceutical and cosmetic. In an effort to further understand the lipid composition of macroalgae, the present work reports, for the first time, the isolation and characterization of the polar lipid profile of the
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Swasono, Respati Tri. "Bioactive secondary metabolites from Australian invertebrates, Indonesian marine sponges, and an Indonesian terrestrial plant /." [St. Lucia, Qld.], 2006. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19275.pdf.

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Mariagiulia, Minetti. "Marine Algae as Source of Bioactive Compounds: Efficacy on Human Osteoarticular Cells." Doctoral thesis, Università di Siena, 2020. http://hdl.handle.net/11365/1096476.

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Marine algae have been demonstrated to be strong candidates for the extraction and enforcement of novel drugs and in recent years, significant development has been achieved in the isolation of these active compounds with several activities, such as anticancer, anti-inflammation, antioxidant, and having an inhibitory effect on ROS generation. Reports relevant to the chemical properties of brown algae Padina sp. are limited and those accompanied to a comprehensive evaluation of the biological activity on osteosarcoma (OS) are non-existent. We explored the chemical composition of French Polynesi
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Mahyudin, Nor Ainy. "Actinomycetes and fungi associated with marine invertebrates: a potential source of bioactive compounds." Thesis, University of Canterbury. Biological Sciences, 2008. http://hdl.handle.net/10092/1496.

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Actinomycetes and fungi were successfully isolated from both New Zealand and Malaysian marine invertebrates and classified as facultatively marine based on their ability to grow on both sea water and non-sea water media. Most of the extracts obtained from selected isolates were cytotoxic. A clear preference of the actinomycetes for solid-state fermentation was observed, however, for fungi no significant preference was seen. Three isolates of Streptomyces spp., four Penicillium spp. and two Paecilomyces spp. whose extracts showed good cytotoxicity were selected for further investigation. A sma
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Zayed, Ahmed Elsayed Ahmed Farag [Verfasser], and Roland [Akademischer Betreuer] Ulber. "Bioactive Compounds from Marine Sources / Ahmed Elsayed Ahmed Farag Zayed ; Betreuer: Roland Ulber." Kaiserslautern : Technische Universität Kaiserslautern, 2018. http://d-nb.info/1162496584/34.

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Zang, Qin. "Towards the total synthesis of peloruside A analogues." Laramie, Wyo. : University of Wyoming, 2008. http://proquest.umi.com/pqdweb?did=1663059931&sid=1&Fmt=2&clientId=18949&RQT=309&VName=PQD.

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Sjögren, Martin. "Bioactive compounds from the marine sponge Geodia barretti : characterization, antifouling activity and molecular targets /." Uppsala : Acta Universitatis Upsaliensis : Universitetsbiblioteket [distributör], 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6797.

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Hedner, Erik. "Bioactive Compounds in the Chemical Defence of Marine Sponges : Structure-Activity Relationships and Pharmacological Targets." Doctoral thesis, Uppsala University, Division of Pharmacognosy, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8218.

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<p>Marine invertebrates, in particular sponges, represent a source of a wide range of secondary metabolites, many of which have been attributed various defensive capabilities against environmental stress factors. In this thesis sponge-derived low-molecular peptide-like compounds and associated analogs are investigated for bioactivity and pharmacological targets. </p><p>The compound bromobenzisoxazolone barettin (cyclo[(6-bromo-8-(6-bromo-benzioxazol -3(1H)-one)-8-hydroxy)tryptophan)]arginine) was isolated from the sponge <i>Geodia barretti</i> and its ability to inhibit larval settlement of th
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Sjögren, Martin. "Bioactive Compounds from the Marine Sponge Geodia barretti : Characterization, Antifouling Activity and Molecular Targets." Doctoral thesis, Uppsala universitet, Institutionen för läkemedelskemi, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6797.

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The marine sponge Geodia barretti produces a range of secondary metabolites. Two of these compounds were isolated and elucidated guided by their ability to inhibit settlement of cypris larvae of the barnacle Balanus improvisus. The compounds barettin (cyclo-[(6-bromo-8-en-tryptophan)-arginine]) as E/Z mixture and 8,9-dihydrobarettin (cyclo-[6-bromo-tryptophan)-arginine]) were determined by using mass spectrometry, nuclear magnetic resonance and quantitative amino acid analysis.The bioactivity of these brominated dipeptides is in the range of antifouling substances used today: EC50 values of 0.
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Ismail, Noraznawati. "Interactions between sponges and marine bacteria as a route to the discovery of novel bioactive compounds." Thesis, Heriot-Watt University, 2006. http://hdl.handle.net/10399/2076.

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The bacterial community architecture associated with four species of sponges, Halichondria panicea, Suberites domuncula, S. carnosus and Pachymatismajohnstonia 'was investigated using culture-dependent and culture-independent strategies. Marine '/ agar was found to be the best of several media used for cultivation of culturable bacteria : associated with sponges. Molecular methods, including denaturing gradient gel ,electrophoresis (DGGE), 16S rDNA cloning and sequence analysis suggested a : bacterial community different from that identified using culture-dependent methods. DGGE can provide a
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Dowle, Katie Orlagh. "New nitrogenous spongian diterpenes from the New Zealand marine sponge Darwinella oxeata : a thesis submitted to the Victoria University of Wellington in fulfilment of the requirements for the degree of Master of [Science] in Chemistry /." ResearchArchive@Victoria e-Thesis, 2008. http://hdl.handle.net/10063/626.

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Thwala, Sazi Selby. "Investigation of the natural products composition from the seaweed ulva capensis." University of Western Cape, 2019. http://hdl.handle.net/11394/7888.

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>Magister Scientiae - MSc<br>In modern society, diversity of marine macroalgae has become an inspiration for pharmaceutical companies and researchers because of their numerous health benefits, and a great deal of interest has developed towards the isolation of bioactive compounds to identify novel marine natural products that could eventually be developed into therapeutics or pharmaceutical products. Furthermore, marine macroalgae are valuable source of structurally diverse metabolites with scientifically proven reports. The search continues as there are many natural bioactive compounds that
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Leite, Carla Andréa [UNESP]. "Influência das condições de cultivo e métodos de extração na produção de metabólitos antioxidantes por fungos isolados do litoral paulista." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/88055.

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Made available in DSpace on 2014-06-11T19:23:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-02-26Bitstream added on 2014-06-13T19:49:48Z : No. of bitstreams: 1 leite_ca_me_araiq.pdf: 5762801 bytes, checksum: bc09a9c50cb41d4cbe82e881237028f7 (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Vários estudos indicam que os antioxidantes podem prevenir e/ou atenuar o dano oxidativo causado pelos radicais livres, os quais em excesso estão associados com várias doenças neurodegenerativas, como Alzheimer e Parkinson. Nos últimos anos houve um aumento na desc
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Mendonça, Iatã do Carmo. "Prospecção química e biológica do endófito Humicola fuscoatra associado a alga vermelha Asparagopsis taxiformis para obtenção de metabólitos secundários bioativos." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/158311.

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Submitted by Iatã do Carmo Mendonça null (iata.mendonca@hotmail.com) on 2018-11-13T19:26:17Z No. of bitstreams: 1 Dissertação Iatã Final.pdf: 6444130 bytes, checksum: 11f109faa73fa111dd02175f3cf51eaf (MD5)<br>Approved for entry into archive by Ana Carolina Gonçalves Bet null (abet@iq.unesp.br) on 2018-11-21T12:18:13Z (GMT) No. of bitstreams: 1 mendonca_ic_me_araiq_int.pdf: 6335142 bytes, checksum: 3275b085559a59aa0ff58a993812c371 (MD5)<br>Made available in DSpace on 2018-11-21T12:18:13Z (GMT). No. of bitstreams: 1 mendonca_ic_me_araiq_int.pdf: 6335142 bytes, checksum: 3275b085559a59aa0ff58
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El, Marrouni El Ghazaoui Abdellatif. "Synthesis of unusual alpha-amino acids and study of the effect of their incorporation into antimicrobial peptides. Total synthesis of biactive marine natural products and analogues thereof." Doctoral thesis, Universitat de Girona, 2012. http://hdl.handle.net/10803/80815.

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The principle theme of this thesis was the synthesis of bioactive compounds. To this end, this work was focus on two main projects. The first one, which was carried out in the Department of Chemistry of the University of Girona under the supervision of Dr Montserrat Heras, concerned the synthesis of new unnatural amino acids bearing a pyrimidine ring within their side chain for incorporation into the antimicrobial peptide BP100 following a rational design in order to improve its biological profile. On the other hand, the second chapter of this thesis was developed in collaboration with the Lab
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Leite, Carla Andréa. "Influência das condições de cultivo e métodos de extração na produção de metabólitos antioxidantes por fungos isolados do litoral paulista /." Araraquara : [s.n.], 2010. http://hdl.handle.net/11449/88055.

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Resumo: Vários estudos indicam que os antioxidantes podem prevenir e/ou atenuar o dano oxidativo causado pelos radicais livres, os quais em excesso estão associados com várias doenças neurodegenerativas, como Alzheimer e Parkinson. Nos últimos anos houve um aumento na descoberta de antioxidantes naturais devido à possibilidade de produção em larga escala a um custo menor que a síntese química. Devido ao seu enorme potencial de exploração, os fungos derivados do ambiente marinho são considerados um dos mais importantes recursos para a obtenção de novos agentes terapêuticos, pois um grande númer
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Clark, Kathryn. "Marine chemical ecology: the search for sequestered and bioactive compounds in the sea hares «dolabrifera dolabrifera» and «stylocheilus striatus» and in their preferred food, the cyanobacterium, «lyngbya majuscula»." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=19264.

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Dolabrifera dolabrifera, an anaspidean mollusc (sea hare) collected from Panama's Coiba National Park, was subjected to its first marine chemical ecology study. Its digestive gland contained 5a,8a-epidioxycholest-6-en-3ß-ol. This compound, documented for the first time in D. dolabrifera, demonstrated activity against the parasite responsible for leishmania (Leishmania donovani). An evaluation of its dietary repertoire revealed that D. dolabrifera significantly preferred the cyanobacterium Lyngbya majuscula over cyanobacter
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Kim, Tae Kyung. "Bioactive compound-producing symbiotic bacteria from marine sponge species : cultural, gene retrieval, and metagenomic studies /." [St. Lucia, Qld.], 2006. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19506.pdf.

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Falaise, Charlotte. "Valorisation des activités biologiques de la diatomée marine Haslea ostrearia." Thesis, Le Mans, 2019. http://www.theses.fr/2019LEMA1011/document.

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Haslea ostrearia est une diatomée cosmopolite pouvant proliférer en milieu naturel et dont les efflorescences sont particulièrement fréquentes dans les claires à huîtres de la côte Atlantique française. Cette diatomée produit la marennine, un pigment bleu-vert hydrosoluble connu pour induire le verdissement des branchies des huîtres, augmentant ainsi leur valeur marchande. La marennine présente des activités allélopathiques, antioxydantes ou encore antibactériennes in vitro et son utilisation en aquaculture a été envisagée suite à la mise en évidence d’effets prophylactiques chez des bivalves.
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CURCURACI, ELEONORA. "Production of high value added nutraceuticals in a multi-trophic aquaculture system within a closed circuit marine hatchery (NUTRAQUA)." Doctoral thesis, Università degli Studi di Palermo, 2022. https://hdl.handle.net/10447/561285.

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Félix, Rafael Alexandre Faria da Costa. "Processing and characterization of seaweed phenolic extractives: a systematic approach." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22781.

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Mestrado em Biotecnologia Molecular<br>As políticas industriais do século XXI têm sido pressionadas para uma mudança que torne sustentável o atual paradigma dos mercados e do desenvolvimento económico. A bioeconomia – assente no aproveitamento integral, na valorização e na recirculação das matérias primas utilizadas na indústria, tanto quanto possível de origem biológica - tem sido vista como uma abordagem promissora. A bioprospecção da biomassa para o desenvolvimento de novas aplicações, nomeadamente no isolamento de compostos bioativos, representa uma das linhas de investigação e desenvolvim
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Perrolas, Inês Madeira. "Bioactive marine compounds as novel therapeutics in osteoarthritis." Master's thesis, 2017. http://hdl.handle.net/10400.1/10052.

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Dissertação de mestrado, Ciências Biomédicas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2017<br>Osteoarthritis (OA) is a whole-joint disease characterized by articular cartilage degeneration, tissue inflammation, abnormal bone formation and extracellular matrix (ECM) mineralization. This disease leads to severely impaired life quality of patients. Currently, there is still no cure or approved therapies capable of modifying the OA course. Treatment is limited to the use of therapeutic strategies with modest efficacy that, in some cases, cause undesirable side effects. The ide
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Almeida, Vanessa Clemente. "Dry powder formulations containing bioactive compounds from marine Actinobacteria." Master's thesis, 2015. http://hdl.handle.net/10362/50886.

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Lower respiratory infections were the leading cause of sickness and mortality in 2013.1 The treatment of such infections relies on antibiotic therapy. However, antibiotic resistance to human pathogens and the prevalence of new cancer types continues to increase, so it is imperative not only to discover new lead-like drugs agents, but also develop new drug delivery systems for pulmonary diseases.2,3 In order to achieve such goal, it was isolated and elucidated antibacterial compounds from a marine-sediment-derived Actinobacteria, collected along Madeira archipelago. These bioactive compounds we
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Costa, Joana Catarina Gomes da. "Design of marine inspired bioactive compounds: synthesis and lipophilicity assessment." Master's thesis, 2019. https://hdl.handle.net/10216/124639.

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Costa, Joana Catarina Gomes da. "Design of marine inspired bioactive compounds: synthesis and lipophilicity assessment." Dissertação, 2019. https://hdl.handle.net/10216/124639.

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João, Susana Afonso. "Unveiling the bioactive potential of marine bacteria." Master's thesis, 2021. http://hdl.handle.net/10773/32822.

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Besides a primary metabolism, living organisms possess a secondary metabolism which allows for the production of secondary metabolites that, normally, are not fundamental to the organism’s growth and survival. These metabolites allow for a better adaptability to their environment as they act as defence mechanisms, can be bioactive against several pathogenic agents and can be used as drugs to efficiently eliminate them. At first, the search for new natural compounds by the scientific community was based on terrestrial environments. However, more recently, more and more attention
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Sabry, Omar Mohamed. "New bioactive natural products from marine algae and cyanobacteria." Thesis, 2004. http://hdl.handle.net/1957/30571.

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This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using bioassay guided fractionation (brine shrimp toxicity assay), I isolated and identified five new, biologically active compounds [2β,3α-epitaondiol, flabellinol, flabellinone, stypoaldehyde and stypohydroperoxide], together with five known comp
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Ismael, Kovan Mohammed. "Marine microalgae as sources of bioactive compounds with anti-inflammatory action." Master's thesis, 2019. http://hdl.handle.net/10400.1/14001.

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Inflammation is a defensive mechanism stimulated when the body is attacked by pathogens or irritants, or when cells are damaged. Sometimes, these defensive mechanisms can go wrong, emerging to different inflammatory diseases, such as acute inflammation and chronic inflammation. Despite the existence of several anti-inflammatory drugs on the market, new drugs with fewer side effects and higher efficacy are required for the treatment of inflammatory diseases. Attention has been given to natural bioactive compounds derived from marine organisms, since these are well known to be a source of potent
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Sá, Joana Daniela Martins de. "Bioactive compounds from the marine derived fungus Neosartorya spinosa KUFA 1047." Master's thesis, 2021. https://hdl.handle.net/10216/136695.

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Tabuada, Mafalda Sutil. "Potential of marine bacteria to synthesize bioactive compounds for medical applications." Master's thesis, 2018. http://hdl.handle.net/10773/25307.

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Pancreatic cancer is one of the deadliest diseases in the world. The best hope for reducing mortality by cancer lies in its early diagnosis and treatment, namely in the detection of lesions that can evolve into cancer stages. On the other hand, traditionally applied therapeutics to fight pancreatic cancer have several drawbacks, namely related with limited efficacy, toxicity to patients, and acquisition of drug resistance. As to counteract this trend, a greater effort has been devoted to the discovery of new anti-pancreatic cancer drugs from biological natural resources. In this context
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Simões, Gabriela Alexandra Rodrigues. "Novel screening platforms construction for detection of new marine microbial bioactive compounds." Master's thesis, 2018. http://hdl.handle.net/10451/36851.

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Tese de mestrado em Biologia Molecular e Genética, apresentada à Universidade de Lisboa, através da Faculdade de Ciências, em 2018<br>Uma parte considerável da biodiversidade da Terra está presente em ecossistemas marinhos. Esta elevada e única biodiversidade marinha tem sido reconhecida como uma importante fonte de variabilidade química, estimando-se que anualmente são descobertos cerca de 1000 compostos de origem marinha. No entanto, o seu conhecimento científico e exploração comercial é ainda reduzido. Uma acumulação de dados científicos que comprovam os benefícios destes compostos marinhos
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Chakkalakal, Selsa Jose. "Bioprospecting Marine Bivalve Mollusks and Cephalopods from South West Coast of India for Potential Bioactive Molecules." Thesis, 2018. http://eprints.cmfri.org.in/14054/1/Thesis_2018_Selsa%20Chakkalakkal.pdf.

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The phylum molluska represents one of the largest and most diverse groups of newlinemarine animals and are considered to be an important source to derive bioactive newlinecompounds. Mollusks contain rich nutrients that are beneficial to people of all ages. Large newlinepopulations, particularly those living in coastal areas relied on these animals for a newlinesubstantial portion of their diet and few reports available in the public domain deal with newlinethe traditional use of mussels against diseases. The consumption of mollusks as popular newlineseafood has increased steadily over the past
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Gomes, Nelson Gonçalo Mortágua. "Isolation, characterization and biological activity evaluation of bioactive compounds from Marine Sponge - Associated Fungi." Doctoral thesis, 2014. https://repositorio-aberto.up.pt/handle/10216/73601.

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Gomes, Nelson Gonçalo Mortágua. "Isolation, characterization and biological activity evaluation of bioactive compounds from Marine Sponge - Associated Fungi." Tese, 2014. https://repositorio-aberto.up.pt/handle/10216/73601.

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Mahmoud, Mohamed Attia Shaaban. "Bioactive Secondary Metabolites from Marine and Terrestrial Bacteria: Isoquinolinequinones, Bacterial Compounds with a Novel Pharmacophor." Doctoral thesis, 2004. http://hdl.handle.net/11858/00-1735-0000-0006-B0DD-7.

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D'Aniello, Filomena. "Characterization of new bioactive natural products from marine sources as pharmaceutical tools and lead compounds in drug discovery processes." Tesi di dottorato, 2014. http://www.fedoa.unina.it/9845/1/d%27aniello%20filomena.pdf.

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Natural products have historically been a rich source of “lead compounds” in drug discovery. The investigation of terrestrial plants and marine organisms aimed at searching new biologically active compounds is a central issue of this kind of studies, trough structure elucidation combined with biological tests. My research activity has been mainly devoted to the discovery and to the chemical and pharmacological investigation of new bioactive natural products as “lead compounds” in the area of antitumor, anti inflammatory and antimalarial activities. My research work, described in this PhD thesi
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Mahmoud, Mohamed Attia Shaaban [Verfasser]. "Bioactive secondary metabolites from marine and terrestrial bacteria: isoquinolinequinones, bacterial compounds with a novel pharmacophor / vorgelegt von Mohamed Attia Shaaban Mahmoud." 2005. http://d-nb.info/974034835/34.

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(3060855), Philip S. Kearns. "Natural products from the Southern Great Barrier Reef." Thesis, 1999. https://figshare.com/articles/thesis/Natural_products_from_the_Southern_Great_Barrier_Reef/21721904.

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<p>Marine organisms are a source of a diverse range of secondary metabolites. This thesis describes the isolation and structure elucidation of novel alkaloid and terpenoid metabolites from marine invertebrates which were collected from the Mackay - Capricorn Section of the Great Barrier Reef Marine Park (Keppel Bay and the Capricorn Bunker Group).</p> <p>B-Carboline, its N,N symmetrical dimer and a series of novel asymmetrical dimers of B-carboline, were isolated from a didemnid ascidian (genus Didemnum). The asymmetrical dimers, however, were isolated in such low yield from the ascidian that
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Rajendran, I. "Bioactive chemicals from marine organisms - Extraction and analysis." Thesis, 2005. http://eprints.cmfri.org.in/7572/1/TH-145.pdf.

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Marine natural products chemistry emerging as a multidisciplinary field drawing attention of chemists, along with pharmacologists and biologists is to explore compounds of novel features both in structure and biological activities. The recent trend of more biological screening along with structural identification of the compounds present in extracts of marine organisms shows that there is increased potential application of these secondary metabolites. The richness in marine bio diversity as the source of various biologically active compounds is now felt extensively. Gulf of Mannar Marin
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Li, Yi-Jie, and 李奕潔. "The study of marine bioactive compound-surfactin in anti-photoaging and moisture." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/69978620464384941245.

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碩士<br>國立臺灣海洋大學<br>水產養殖學系<br>104<br>Surfactin is an amphipathic cyclic lipopeptide molecule derived from aquatic probiotics, Bacillus subtilis, secondary metabolites. This molecule also had seen shown promising as an anti-bacteria, anti-coagulant and transdermal penetration enhancer. The lipopeptides are amphiphatic and consist of a hydrophobic chain containing from about 8 to 24 carbon atoms and a peptide chain that is hydrophilic or has been rendered hydrophilic. The applications for lipopeptides has been in anti-wrinkle, antiaging, and rejunenation cosmetics(Wu and Lu, 2011). Nowaday cosmeti
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Fernandes, Tomásia Micaela Gomez. "Enrichment of bioactive compounds in microalgae for aquaculture." Master's thesis, 2015. http://hdl.handle.net/10400.13/1153.

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Microalgae are promising microorganisms for the production of food and fine chemicals. Several species of microalgae are used in aquaculture with the purpose of transfer bioactive compounds up to the aquatic food chain. The main objective of this project was to develop a stress–inducement strategy in order to enhance the biochemical productivity of Nannochloropsis gaditana, Rhodomonas marina and Isochrysis sp. for aquaculture purposes having in account their growth and organizational differences. In this regard, two experiments were design: the first one consisted on the alteration of overall
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Silva, Joana Margarida Agarez Monteiro Cerca da. "Metabolitos secundários das macroalgas castanhas de elevado potencial para a indústria farmacêutica." Master's thesis, 2021. http://hdl.handle.net/10284/9642.

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Nos últimos anos, a procura por novos compostos para utilização pela indústria farmacêutica conduziu a um aumento dos estudos com espécies marinhas, uma vez que a sua aplicabilidade para fins terapêuticos é conhecida por parte de comunidades costeiras desde tempos remotos. O ambiente marinho tem evidenciado uma grande biodiversidade de espécies que demonstraram possuir a capacidade de sintetizar vários compostos com elevado potencial farmacológico. Assim, a indústria farmacêutica tem investido na extração, identificação e estudos de várias moléculas que constituem metabolitos de es
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