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1

Özkaya, Ferhat Can, Cem Erdoğan, and Muhammet Altunok. "Denizel biyoaktif bileşikler." Ege Journal of Fisheries and Aquatic Sciences 30, no. 2 (2013): 85–92. http://dx.doi.org/10.12714/egejfas.2013.30.2.08.

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Avila, Conxita, and Carlos Angulo-Preckler. "Bioactive Compounds from Marine Heterobranchs." Marine Drugs 18, no. 12 (2020): 657. http://dx.doi.org/10.3390/md18120657.

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The natural products of heterobranch molluscs display a huge variability both in structure and in their bioactivity. Despite the considerable lack of information, it can be observed from the recent literature that this group of animals possesses an astonishing arsenal of molecules from different origins that provide the molluscs with potent chemicals that are ecologically and pharmacologically relevant. In this review, we analyze the bioactivity of more than 450 compounds from ca. 400 species of heterobranch molluscs that are useful for the snails to protect themselves in different ways and/or
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Solanki, Renu, Monisha Khanna, and Rup Lal. "Bioactive compounds from marine actinomycetes." Indian Journal of Microbiology 48, no. 4 (2008): 410–31. http://dx.doi.org/10.1007/s12088-008-0052-z.

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Higa, Tatsuo, J. I. Tanaka, Atsushi Kitamura, Tomoyuki Koyama, M. Takahashia, and T. Uchida. "Bioactive compounds from marine sponges." Pure and Applied Chemistry 66, no. 10-11 (1994): 2227–30. http://dx.doi.org/10.1351/pac199466102227.

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Tamzi, Nafisa Nawar, Md Motiur Rahman, and Subhadeep Das. "Recent Advances in Marine-Derived Bioactives Towards Cancer Therapy." International Journal of Translational Medicine 4, no. 4 (2024): 740–81. https://doi.org/10.3390/ijtm4040051.

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The increase in cancer incidence in recent years necessitates urgent exploration of novel and alternative sources of natural bioactives for targeted cancer therapy. Approximately 75% of the Earth’s surface is covered by oceans, which are thought to harbor untapped physiologically active compounds with potential efficacy against cancer. Recently, a growing focus has been on isolating and investigating novel bioactive compounds derived from marine sources. Bioactive metabolites with diverse chemical structures, isolated from various marine species such as algae, mollusks, and actinomycetes, demo
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Kalyani., P* Hemalatha. K. P. J. "REVIEW PAPER-MARINE MICROBIAL BIOACTIVE COMPOUNDS." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 5, no. 11 (2016): 124–33. https://doi.org/10.5281/zenodo.164910.

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Oceans have borne most of the biological activities on our planet. A number of biologically active compounds with varying degrees of action, such as anti-tumor, anti-cancer, anti-microtubule, anti-proliferative, cytotoxic, photo protective, as well as antibiotic and antifouling properties, have been isolated to date from marine sources. The marine environment also represents a largely unexplored source for isolation of new microbes (bacteria, fungi, actinomycetes, microalgae-cyanobacteria and diatoms) that are potent producers of bioactive secondary metabolites. Extensive research has been don
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Tiwari, Abhitav, Shambhawi Pritam, Keerti Mishra, Mehshara Khan, Neeraj Upmanyu, and Dipanjana Ghosh. "Nutraceuticals from Marine Bionetworks." Current Nutrition & Food Science 15, no. 4 (2019): 338–44. http://dx.doi.org/10.2174/1573401314666180109153825.

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“Nutrition” and “Pharmaceutical” together build up the perception of “Nutraceuticals” that refer to the food or dietary supplements that help to incorporate additional health benefits to the fundamental sustenance accomplished on daily basis. Each nutraceutical contains one or more bioactive molecules that are usually obtained by chemical and/ or biotechnological synthesis or by extraction from natural sources. Among the natural sources, marine bionetwork possess immense potential for the presence of bioactive compounds. Some of these bioactive compounds as isolated from marine sources, have p
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Datta, D., S. Nath Talapatra, and S. Swarnakar. "Bioactive Compounds from Marine Invertebrates for Potential Medicines - An Overview." International Letters of Natural Sciences 34 (February 2015): 42–61. http://dx.doi.org/10.18052/www.scipress.com/ilns.34.42.

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The present review deals with the bioactive compounds of the marine non-chordates. The potent medicinal usage of the bioactive compounds viz. steroids, terpenoids, isoprenoid and non-isoprenoid compounds, quinones, brominated compounds, nitrogen heterocyclics and nitrogen-sulphur heterocyclics from marine non-chordates have been compiled. Various literatures survey revealed that the bioactive compounds isolated in recent past from the marine poriferans, cnidarians, annelids, arthropods, molluscs and echinoderms could be rich sources of therapeutic agents having antibacterial, antiinflamatory,
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Datta, D., S. Nath Talapatra, and S. Swarnakar. "Bioactive Compounds from Marine Invertebrates for Potential Medicines - An Overview." International Letters of Natural Sciences 34 (February 17, 2015): 42–61. http://dx.doi.org/10.56431/p-i22ej9.

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The present review deals with the bioactive compounds of the marine non-chordates. The potent medicinal usage of the bioactive compounds viz. steroids, terpenoids, isoprenoid and non-isoprenoid compounds, quinones, brominated compounds, nitrogen heterocyclics and nitrogen-sulphur heterocyclics from marine non-chordates have been compiled. Various literatures survey revealed that the bioactive compounds isolated in recent past from the marine poriferans, cnidarians, annelids, arthropods, molluscs and echinoderms could be rich sources of therapeutic agents having antibacterial, antiinflamatory,
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Kiuru, Paula, M. DʼAuria, Christian Muller, Päivi Tammela, Heikki Vuorela, and Jari Yli-Kauhaluoma. "Exploring Marine Resources for Bioactive Compounds." Planta Medica 80, no. 14 (2014): 1234–46. http://dx.doi.org/10.1055/s-0034-1383001.

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Sepčić, Kristina. "BIOACTIVE ALKYLPYRIDINIUM COMPOUNDS FROM MARINE SPONGES." Journal of Toxicology: Toxin Reviews 19, no. 2 (2000): 139–60. http://dx.doi.org/10.1081/txr-100100318.

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Raj, Bincy, D. S. Seetharam, and Sharangouda Patil. "Green extraction of bioactive compounds from marine constituents." Scripta Medica 56, no. 2 (2025): 329–41. https://doi.org/10.5937/scriptamed56-52550.

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Marine organisms house diverse bioactive compounds, making them a prime focus in marine pharmacology. This abstract explores eco-friendly extraction methods for isolating bioactive marine constituents and peptides from marine sources, underscoring their sustainability and environmental responsibility. Green extraction technologies include supercritical fluid extraction (SFE), pressurised solvent extraction (PSE) and enzyme extraction using microwaves and ultrasounds. Since there is less chemical interference, these newer, greener technologies would be safer. The extraction, isolation and chara
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Perera, R. M. T. D., K. H. I. N. M. Herath, K. K. Asanka Sanjeewa, and Thilina U. Jayawardena. "Recent Reports on Bioactive Compounds from Marine Cyanobacteria in Relation to Human Health Applications." Life 13, no. 6 (2023): 1411. http://dx.doi.org/10.3390/life13061411.

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The ocean is a valuable natural resource that contains numerous biologically active compounds with various bioactivities. The marine environment comprises unexplored sources that can be utilized to isolate novel compounds with bioactive properties. Marine cyanobacteria are an excellent source of bioactive compounds that have applications in human health, biofuel, cosmetics, and bioremediation. These cyanobacteria exhibit bioactive properties such as anti-inflammatory, anti-cancer, anti-bacterial, anti-parasitic, anti-diabetic, anti-viral, antioxidant, anti-aging, and anti-obesity effects, maki
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Venkateskumar, Krishnamoorthy, Subramani Parasuraman, Leow Y. Chuen, Veerasamy Ravichandran, and Subramani Balamurgan. "Exploring Antimicrobials from the Flora and Fauna of Marine: Opportunities and Limitations." Current Drug Discovery Technologies 17, no. 4 (2020): 507–14. http://dx.doi.org/10.2174/1570163816666190819141344.

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About 95% of earth living space lies deep below the ocean’s surface and it harbors extraordinary diversity of marine organisms. Marine biodiversity is an exceptional reservoir of natural products, bioactive compounds, nutraceuticals and other potential compounds of commercial value. Timeline for the development of the drug from a plant, synthetic and other alternative sources is too lengthy. Exploration of the marine environment for potential bioactive compounds has gained focus and huge opportunity lies ahead for the exploration of such vast resources in the ocean. Further, the evolution of s
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15

Li, Tingting, Ting Ding, and Jianrong Li. "Medicinal Purposes: Bioactive Metabolites from Marine-derived Organisms." Mini-Reviews in Medicinal Chemistry 19, no. 2 (2018): 138–64. http://dx.doi.org/10.2174/1389557517666170927113143.

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The environment of marine occupies about 95% biosphere of the world and it can be a critical source of bioactive compounds for humans to be explored. Special environment such as high salt, high pressure, low temperature, low nutrition and no light, etc. has made the production of bioactive substances different from terrestrial organisms. Natural ingredients secreted by marine-derived bacteria, fungi, actinomycetes, Cyanobacteria and other organisms have been separated as active pharmacophore. A number of evidences have demonstrated that bioactive ingredients isolated from marine organisms can
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16

Ribas-Taberner, Maria del Mar, Pere Miquel Mir-Rossello, Lorenzo Gil, Antoni Sureda, and Xavier Capó. "Potential Use of Marine Plants as a Source of Bioactive Compounds." Molecules 30, no. 3 (2025): 485. https://doi.org/10.3390/molecules30030485.

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The search for bioactive natural compounds, traditionally focused on terrestrial environments, has increasingly expanded to the seas and oceans, opening new frontiers for exploration. Among the diverse organisms inhabiting these ecosystems, marine phanerogams have emerged as a promising source of health-promoting bioactive compounds. This review highlights the distinctive chemical diversity of seagrasses including species such as Posidonia oceanica, Zostera marina, and Cymodocea nodosa, among others, and focusses on the growing interest in natural therapies as alternatives to conventional phar
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Kim, Ji, Jae-Eun Lee, Kyoung Kim, and Nam Kang. "Beneficial Effects of Marine Algae-Derived Carbohydrates for Skin Health." Marine Drugs 16, no. 11 (2018): 459. http://dx.doi.org/10.3390/md16110459.

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Marine algae are considered to be an abundant sources of bioactive compounds with cosmeceutical potential. Recently, a great deal of interest has focused on the health-promoting effects of marine bioactive compounds. Carbohydrates are the major and abundant constituent of marine algae and have been utilized in cosmetic formulations, as moisturizing and thickening agents for example. In addition, marine carbohydrates have been suggested as promising bioactive biomaterials for their various properties beneficial to skin, including antioxidant, anti-melanogenic and skin anti-aging properties. The
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Dyshlovoy, Sergey A., and Friedemann Honecker. "Marine Compounds and Cancer: Updates 2022." Marine Drugs 20, no. 12 (2022): 759. http://dx.doi.org/10.3390/md20120759.

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Mateos, Raquel, José Ricardo Pérez-Correa, and Herminia Domínguez. "Bioactive Properties of Marine Phenolics." Marine Drugs 18, no. 10 (2020): 501. http://dx.doi.org/10.3390/md18100501.

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Phenolic compounds from marine organisms are far less studied than those from terrestrial sources since their structural diversity and variability require powerful analytical tools. However, both their biological relevance and potential properties make them an attractive group deserving increasing scientific interest. The use of efficient extraction and, in some cases, purification techniques can provide novel bioactives useful for food, nutraceutical, cosmeceutical and pharmaceutical applications. The bioactivity of marine phenolics is the consequence of their enzyme inhibitory effect and ant
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R. Siral, Vaishnavi, Dinesh Gujrathi, Pravin Ghule, Mahesh Bhakare, Sonal Dholtade, and Janardan Khandekar. "Potential of Marine Compound’s as an Anticancer Activity." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 726–33. https://doi.org/10.35629/4494-1002726733.

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A number of novel compounds, which are produced in the marine environment, have been found to exhibit the anticancer effects Some marine organisms cytarabine, eribulin mesylate, brentuximab vedotin, and trabectidine have proved to be important producers of chemically active compounds with valuable bioactive properties, including anticancer. Thus, the ocean has proved to be a huge source of bioactive compounds, making the discovery and study of these compounds a growing area. Cancer remains one of the most lethal diseases worldwide. There is an urgent need for new drugs with novel modes of acti
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Narayanankutty, Arunaksharan, Ademola C. Famurewa, and Eliza Oprea. "Natural Bioactive Compounds and Human Health." Molecules 29, no. 14 (2024): 3372. http://dx.doi.org/10.3390/molecules29143372.

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Izzati, Fauzia, Mega Ferdina Warsito, Asep Bayu, et al. "Chemical Diversity and Biological Activity of Secondary Metabolites Isolated from Indonesian Marine Invertebrates." Molecules 26, no. 7 (2021): 1898. http://dx.doi.org/10.3390/molecules26071898.

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Marine invertebrates have been reported to be an excellent resource of many novel bioactive compounds. Studies reported that Indonesia has remarkable yet underexplored marine natural products, with a high chemical diversity and a broad spectrum of biological activities. This review discusses recent updates on the exploration of marine natural products from Indonesian marine invertebrates (i.e., sponges, tunicates, and soft corals) throughout 2007–2020. This paper summarizes the structural diversity and biological function of the bioactive compounds isolated from Indonesian marine invertebrates
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Yurchenko, Ekaterina A. "Bioactive Compounds from Marine Sediment Derived Fungi." Marine Drugs 20, no. 4 (2022): 242. http://dx.doi.org/10.3390/md20040242.

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Debbab, Abdessamad, Amal H. Aly, Wen H. Lin, and Peter Proksch. "Bioactive Compounds from Marine Bacteria and Fungi." Microbial Biotechnology 3, no. 5 (2010): 544–63. http://dx.doi.org/10.1111/j.1751-7915.2010.00179.x.

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Zhang, Lixin, Rong An, Jinping Wang, et al. "Exploring novel bioactive compounds from marine microbes." Current Opinion in Microbiology 8, no. 3 (2005): 276–81. http://dx.doi.org/10.1016/j.mib.2005.04.008.

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Pandey, Abhishek. "Pharmacological significance of marine microbial bioactive compounds." Environmental Chemistry Letters 17, no. 4 (2019): 1741–51. http://dx.doi.org/10.1007/s10311-019-00908-7.

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HIGA, T., J. TANAKA, A. KITAMURA, T. KOYAMA, M. TAKAHASHI, and T. UCHIDA. "ChemInform Abstract: Bioactive Compounds from Marine Sponges." ChemInform 26, no. 7 (2010): no. http://dx.doi.org/10.1002/chin.199507341.

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Senadheera, Tharindu R. L., Abul Hossain, and Fereidoon Shahidi. "Marine Bioactives and Their Application in the Food Industry: A Review." Applied Sciences 13, no. 21 (2023): 12088. http://dx.doi.org/10.3390/app132112088.

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The structurally diverse bioactive compounds found in marine organisms represent valuable resources for the food and pharmaceutical industries. The marine ecosystem encompasses over half of the world’s biota, providing an extensive range of bioactive compounds that can be extracted from various marine life forms, including marine microorganisms (such as bacteria, cyanobacteria, and actinobacteria), algae (both macroalgae and microalgae), invertebrates (including sponges, mollusks, echinoderms, and crustaceans), and, most importantly, fish. Many of these organisms thrive in extreme marine envir
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Tringali, C. "Bioactive Metabolites From Marine Algae: Recent Results*." Current Organic Chemistry 1, no. 4 (1997): 375–94. http://dx.doi.org/10.2174/1385272801666220126161423.

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The recent literature (1992 - early 1996) on secondary metabolites from marine algae has been reviewed and selected results concerning more than one hundred bioactive compounds are reported. The review is specifically devoted to the seaweeds (Chlorophyta, Phaeophyta and Rhodophyta) and does not include metabolites from microalgae and Cyanobacteria (blue-green algae). Emphasis has been placed on novel compounds, but some recent reports about previously known bioactive metabolites have also been reviewed. A variety of bioactive metabolites has recently been obtained from marine algae, including
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Carroll, Anthony R., Brent R. Copp, Rohan A. Davis, Robert A. Keyzers, and Michèle R. Prinsep. "Marine natural products." Natural Product Reports 37, no. 2 (2020): 175–223. http://dx.doi.org/10.1039/c9np00069k.

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Sang, Dat, Vinh, et al. "Coral and Coral-Associated Microorganisms: A Prolific Source of Potential Bioactive Natural Products." Marine Drugs 17, no. 8 (2019): 468. http://dx.doi.org/10.3390/md17080468.

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Marine invertebrates and their associated microorganisms are rich sources of bioactive compounds. Among them, coral and its associated microorganisms are promising providers of marine bioactive compounds. The present review provides an overview of bioactive compounds that are produced by corals and coral-associated microorganisms, covering the literature from 2010 to March 2019. Accordingly, 245 natural products that possess a wide range of potent bioactivities, such as anti-inflammatory, cytotoxic, antimicrobial, antivirus, and antifouling activities, among others, are described in this revie
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Ma, Ruijuan, Baobei Wang, Elvis T. Chua, et al. "Comprehensive Utilization of Marine Microalgae for Enhanced Co-Production of Multiple Compounds." Marine Drugs 18, no. 9 (2020): 467. http://dx.doi.org/10.3390/md18090467.

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Marine microalgae are regarded as potential feedstock because of their multiple valuable compounds, including lipids, pigments, carbohydrates, and proteins. Some of these compounds exhibit attractive bioactivities, such as carotenoids, ω-3 polyunsaturated fatty acids, polysaccharides, and peptides. However, the production cost of bioactive compounds is quite high, due to the low contents in marine microalgae. Comprehensive utilization of marine microalgae for multiple compounds production instead of the sole product can be an efficient way to increase the economic feasibility of bioactive comp
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Varijakzhan, Disha, Jiun-Yan Loh, Wai-Sum Yap, et al. "Bioactive Compounds from Marine Sponges: Fundamentals and Applications." Marine Drugs 19, no. 5 (2021): 246. http://dx.doi.org/10.3390/md19050246.

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Marine sponges are sessile invertebrates that can be found in temperate, polar and tropical regions. They are known to be major contributors of bioactive compounds, which are discovered in and extracted from the marine environment. The compounds extracted from these sponges are known to exhibit various bioactivities, such as antimicrobial, antitumor and general cytotoxicity. For example, various compounds isolated from Theonella swinhoei have showcased various bioactivities, such as those that are antibacterial, antiviral and antifungal. In this review, we discuss bioactive compounds that have
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Li, Xiaohui, Hejing Zhao, and Xiaolin Chen. "Screening of Marine Bioactive Antimicrobial Compounds for Plant Pathogens." Marine Drugs 19, no. 2 (2021): 69. http://dx.doi.org/10.3390/md19020069.

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Plant diseases have been threatening food production. Controlling plant pathogens has become an important strategy to ensure food security. Although chemical control is an effective disease control strategy, its application is limited by many problems, such as environmental impact and pathogen resistance. In order to overcome these problems, it is necessary to develop more chemical reagents with new functional mechanisms. Due to their special living environment, marine organisms have produced a variety of bioactive compounds with novel structures, which have the potential to develop new fungic
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Yoswaty, Dessy, Nursyirwani, Isma Mulyani, and Michael Parluhutan Jupiter Sibarani. "Screening of bioactive compounds and antibacterial activity of avicennia marina leaf extract against pathogenic bacteria." BIO Web of Conferences 74 (2023): 04006. http://dx.doi.org/10.1051/bioconf/20237404006.

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High levels of marine pollution are thought to trigger the growth of pathogenic bacteria and cause disease in farmed fish. One of the natural antibiotic alternatives to inhibit the growth of pathogenic bacteria is Avicennia marina leaf extract. A. marina leaves extract is thought to produce bioactive compounds, antibacterial and stimulate the growth of endophytic bacteria. The study aimed to screen bioactive compounds and antibacterial activity of A. marina leaf extract against pathogenic bacteria. This survey research was conducted from March to May 2023. A fermentation process of mangrove le
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Al-Hussaniy, Hany A., Sammar Jassim Mahan, Zainab Mohamed Redha, et al. "Marine-derived bioactive molecules as modulators of immune pathways: A molecular insight into pharmacological potential." Pharmacia 72 (February 19, 2025): 1–10. https://doi.org/10.3897/pharmacia.72.e141923.

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Background: Marine ecosystems are a vast reservoir of bioactive compounds with immense pharmacological potential. Objectives: This review explores the molecular mechanisms of action, potential therapeutic applications, and challenges in the clinical translation of marine-derived bioactive molecules targeting immune pathways. Methods: A comprehensive literature review was conducted, analyzing studies on the immunomodulatory effects of marine-derived polysaccharides, peptides, and secondary metabolites. Result: In recent years, molecules derived from marine organisms, such as polysaccharides, pe
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Al-Hussaniy, Hany A., Sammar Jassim Mahan, Zainab Mohamed Redha, et al. "Marine-derived bioactive molecules as modulators of immune pathways: A molecular insight into pharmacological potential." Pharmacia 72 (February 19, 2025): 1–10. https://doi.org/10.3897/pharmacia.72.e141923.

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Background: Marine ecosystems are a vast reservoir of bioactive compounds with immense pharmacological potential. Objectives: This review explores the molecular mechanisms of action, potential therapeutic applications, and challenges in the clinical translation of marine-derived bioactive molecules targeting immune pathways. Methods: A comprehensive literature review was conducted, analyzing studies on the immunomodulatory effects of marine-derived polysaccharides, peptides, and secondary metabolites. Result: In recent years, molecules derived from marine organisms, such as polysaccharides, pe
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Generalić Mekinić, Ivana, and Vida Šimat. "Marine Algae Bioactives: Isolation, Characterization, and Potential Application." Foods 13, no. 11 (2024): 1736. http://dx.doi.org/10.3390/foods13111736.

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This Special Issue (SI) of Foods, entitled “Marine Algae Bioactives: Isolation, Characterization, and Potential Application”, was focused on algal organisms, both microalgae and macroalgae, which have recently been recognized as new, cost-effective, and valuable sources of health-promoting nutrients and bioactive compounds with a full spectrum of activities and beneficial effects on health [...]
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Ain Nafiza Basha, Fazrena Nadia Md Akhir, Nor’azizi Othman, and Hirofumi Hara. "Anticancer Potential of Bioactive Compounds from Microalgae. A Review." Journal of Advanced Research in Micro and Nano Engieering 20, no. 1 (2024): 1–9. http://dx.doi.org/10.37934/armne.20.1.19.

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In this review, we discussed the important breakthroughs in the field of cancer treatment involving algae and microalgae. The continuous development and commercialization of marine drugs has been a rewarding scientific endeavour. The pipeline of marine-derived anticancer agents provides promising treatment options for patients with certain types of cancer. With the approval of four drugs and eighteen agents in late development, the pipeline of marine-derived anticancer drugs is one of the most robust in the industry. Natural products containing bioactive components have been increasingly popul
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Kalyani, A. Khajure Pooja B. Rasal*. "Marine-Derived Products for Cosmeceuticals: A Comprehensive Review." International Journal of Scientific Research and Technology 1, no. 11 (2024): 1–12. https://doi.org/10.5281/zenodo.14092144.

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Marine-derived products are gaining increasing attention in the cosmeceutical industry due to their unique bioactive compounds, which offer exceptional therapeutic benefits for skin health and beauty. These bioactive compounds, including peptides, polysaccharides, fatty acids, and antioxidants, have demonstrated powerful effects in promoting skin regeneration, moisturizing, anti-aging, anti-inflammatory, and skin protection. This review provides an overview of various marine-derived ingredients, their mechanisms of action, and their applications in cosmeceuticals. It also highlights recent dev
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Abuhijjleh, Reham K., Samiullah Shabbir, Ahmed M. Al-Abd, et al. "Bioactive marine metabolites derived from the Persian Gulf compared to the Red Sea: similar environments and wide gap in drug discovery." PeerJ 9 (July 28, 2021): e11778. http://dx.doi.org/10.7717/peerj.11778.

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Marine life has provided mankind with unique and extraordinary chemical structures and scaffolds with potent biological activities. Many organisms and secondary metabolites derived from fungi and symbionts are found to be more environmentally friendly to study than the marine corals per se. Marine symbionts such as Aspergillus sp., a fungus, which can be isolated and grown in the lab would be a potential and continuous source of bioactive natural compounds without affecting the marine environment. The Red Sea is known for its biodiversity and is well-studied in terms of its marine-derived bioa
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Krishnamurthy, Vishwakarma Ravindrakumar, and B. Kirthiga. "A Comprehensive Study on Marine Sample Collection Techniques for Xanthone Screening." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 15 (2024): 466–81. http://dx.doi.org/10.56557/upjoz/2024/v45i154263.

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This study focuses on the collection of marine samples and the subsequent screening of xanthone compounds from the marine fungi Aspergillus sydowii. Marine fungi, especially those from the genus Aspergillus, are known for producing a wide array of bioactive compounds with significant therapeutic potential. The primary objective was to isolate and identify fungal strains capable of producing xanthones and evaluate their bioactive properties. Samples were collected from various marine environments, including coastal waters and deep-sea sediments, and preserved under sterile conditions. Fungal is
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Ghaliaoui, Nora, Mohamed Hazzit, and Hind Mokrane. "Seaweeds as a Potential Source of Bioactive Compounds." Research in Biotechnology and Environmental Science 3, no. 1 (2024): 1–8. http://dx.doi.org/10.58803/rbes.v3i1.19.

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Seaweeds or marine macroalgae are the oldest members of the plant kingdom, with a history extending back many hundreds of millions of years. Based on photosynthetic pigments, marine macroalgae can be classified into three groups, namely green algae commonly known as Chlorophyta, brown algae or Phaeophyta, and red algae also called Rhodophyta. In response to different kinds of environmental stress, marine algae develop defense strategies resulting in a significant level of structural chemical diversity, from different metabolic pathways. In this review a brief description of the most important
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C.S., Vidhya, Susmi Biswas, Sourav Gangopadhyay, et al. "Exploring Human Health Benefits from Marine Biomedical Research with Fishes." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 11 (2024): 59–68. http://dx.doi.org/10.56557/upjoz/2024/v45i114070.

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Marine organisms, particularly fishes, harbor a treasure trove of bioactive compounds with immense potential for human health applications. In this review, we delve into the diverse array of bioactive molecules derived from marine fishes and their implications for biomedical research. We explore the therapeutic properties of fish-derived compounds, including antimicrobial peptides, omega-3 fatty acids, collagen, and bioactive peptides, among others andthe mechanisms of action and preclinical studies supporting the use of these compounds in various human health conditions, such as cardiovascula
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Sepe, Fabrizia, Anna Valentino, Loredana Marcolongo, et al. "Marine-Derived Polysaccharide Hydrogels as Delivery Platforms for Natural Bioactive Compounds." International Journal of Molecular Sciences 26, no. 2 (2025): 764. https://doi.org/10.3390/ijms26020764.

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Marine polysaccharide hydrogels have emerged as an innovative platform for regulating the in vivo release of natural bioactive compounds for medical purposes. These hydrogels, which have exceptional biocompatibility, biodegradability, and high water absorption capacity, create effective matrices for encapsulating different bioactive molecules. In addition, by modifying the physical and chemical properties of marine hydrogels, including cross-linking density, swelling behavior, and response to external stimuli like pH, temperature, or ionic strength, the release profile of encapsulated bioactiv
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Soliev, Azamjon B., Kakushi Hosokawa, and Keiichi Enomoto. "Bioactive Pigments from Marine Bacteria: Applications and Physiological Roles." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–17. http://dx.doi.org/10.1155/2011/670349.

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Research into natural products from the marine environment, including microorganisms, has rapidly increased over the past two decades. Despite the enormous difficulty in isolating and harvesting marine bacteria, microbial metabolites are increasingly attractive to science because of their broad-ranging pharmacological activities, especially those with unique color pigments. This current review paper gives an overview of the pigmented natural compounds isolated from bacteria of marine origin, based on accumulated data in the literature. We review the biological activities of marine compounds, i
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Esposito, Roberta, Serena Federico, Marco Bertolino, Valerio Zupo, and Maria Costantini. "Marine Demospongiae: A Challenging Treasure of Bioactive Compounds." Marine Drugs 20, no. 4 (2022): 244. http://dx.doi.org/10.3390/md20040244.

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In the last decades, it has been demonstrated that marine organisms are a substantial source of bioactive compounds with possible biotechnological applications. Marine sponges, in particular those belonging to the class of Demospongiae, have been considered among the most interesting invertebrates for their biotechnological potential. In this review, particular attention is devoted to natural compounds/extracts isolated from Demospongiae and their associated microorganisms with important biological activities for pharmacological applications such as antiviral, anticancer, antifouling, antimicr
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Lee, Heesu, Baskar Selvaraj, and Jae Wook Lee. "Anticancer Effects of Seaweed-Derived Bioactive Compounds." Applied Sciences 11, no. 23 (2021): 11261. http://dx.doi.org/10.3390/app112311261.

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Cancer remains a major life-threatening disease worldwide. The development of anticancer drugs using natural products obtained from marine organisms has been proposed as an alternative approach. Seaweeds are the mainstay of marine ecosystems; therefore, they are highly enriched with diverse bioactive compounds. In the past decade, a vast number of natural compounds, such as polysaccharides, polyphenols, carotenoids, and terpenoids, have been isolated from seaweeds. Seaweeds have bioactive compounds that show cytotoxicity in various cancer cell lines. These compounds prevent tumor growth by ind
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S Ellithey, Mona, and Hanaa H Ahmed. "BIOACTIVE MARINE-DERIVED COMPOUNDS AS POTENTIAL ANTICANCER CANDIDATES." Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (2018): 464. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.28954.

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Objective: The objective of this research was to evaluate for the 1st time the anticancer activities of sarcophytol M (1), alismol (2), alismoxide (5), 7β-acetoxy-24-methylcholesta-5-24(28)-diene-3,19-diol (7), erythro-N-dodecanoyl-docosasphinga-(4E,8E)-dienine (8), and 24 methylcholesta- 5,24(28)-diene-3β,7β,19-triol (9). Compounds were isolated from the soft coral Lithophyton arboreum and tested in liver (HepG2), lung (A549), and breast (MDA) cancer cell line.Methods: Anticancer activities of the compounds were tested using (XTT) 2,3-bis-(2-methoxy-4-nitro- 5-sulfophenyl)-2H-tetrazolium-5-ca
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Lasalo, Malia, Thierry Jauffrais, Philippe Georgel, and Mariko Matsui. "Marine Microorganism Molecules as Potential Anti-Inflammatory Therapeutics." Marine Drugs 22, no. 9 (2024): 405. http://dx.doi.org/10.3390/md22090405.

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The marine environment represents a formidable source of biodiversity, is still largely unexplored, and has high pharmacological potential. Indeed, several bioactive marine natural products (MNPs), including immunomodulators, have been identified in the past decades. Here, we review how this reservoir of bioactive molecules could be mobilized to develop novel anti-inflammatory compounds specially produced by or derived from marine microorganisms. After a detailed description of the MNPs exerting immunomodulatory potential and their biological target, we will briefly discuss the challenges asso
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