Gotowa bibliografia na temat „MPEG Lysinol Ring opening polymerization”

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Artykuły w czasopismach na temat "MPEG Lysinol Ring opening polymerization"

1

Geng, Dian Guang, Yong Ming Chuan, Li Li Li, and Ming Long Yuan. "The Preparation and Characterization of ABC-Shaped Star Copolymer of MPEG-PCL-PBLG." Advanced Materials Research 750-752 (August 2013): 1358–62. http://dx.doi.org/10.4028/www.scientific.net/amr.750-752.1358.

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A novel biodegradable ABC-shaped star copolymer, poly (ethylene glycol)(PEG)-b-poly (ε-caprolactone)(PCL)-poly-c-poly (ɤ-benzyl-L-glutamic acid)(PBLG)(MPEG-PCL-PBLG), was synthesized by the graft polymerization of MPEG-NH2with the core of Boc-LYSZ-COOH and the twice ring-opening polymerization (ROP) of ε-caprolactone (CL) and N-carboxyanhydride of ɤ-benzyl-L-glutamate (BLGNCA) with centrally amino-functionalized lysine as a initiator. The ABC-shaped star copolymer and its precursors were characterized by1H NMR, GPC, and DSC-TG measurements.
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Cheng, Yu-En, I.-En Wu, Yi-Chen Chen, and I.-Ming Chu. "Thermo-Sensitive mPEG-PA-PLL Hydrogel for Drug Release of Calcitonin." Gels 8, no. 5 (2022): 282. http://dx.doi.org/10.3390/gels8050282.

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The oral route is the most popular way of drug administration because of good patient compliance and ease of use. However, the oral delivery of peptides and proteins is difficult, mainly due to poor oral bioavailability. In past decades, researchers have developed several strategies to improve oral bioavailability by avoiding losing activity in the gastrointestinal (GI) tract and enhancing the intestinal permeability of these drugs. Methoxy poly(ethylene glycol)-poly(l-alanine) (mPEG-PA) is a thermo-sensitive hydrogel exhibiting a sol-to-gel phase transition property. This characteristic is ap
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Efthimiadou, Eleni. "New approach in synthesis, characterization and release study of pH-sensitive polymeric micelles, based on PLA-Lys-b-PEGm, conjugated with doxorubicin." Journal of nanoparticle research 13, no. 12 (2011): 6725–36. https://doi.org/10.1007/s11051-011-0579-5.

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Amphiphilic block copolymers are well established as building blocks for the preparation of micellar drug carriers. The functional polymer micelles possess several advantages, such as high drug efficiency, targeted delivery, and minimized cytotoxicity. The synthesis of block copolymers using nanostructured templates has emerged as a useful and versatile approach for preparing drug carriers. Here, we report the synthesis of a smart polymeric compound of a diblock PLA-Lys-b-PEG copolymer containing doxorubicin. We have synthesized functionalized diblock copolymers, with lysinol, poly(lactide) an
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Qi, Yanxin, Bin Li, Yupeng Wang, and Yubin Huang. "Synthesis and sequence-controlled self-assembly of amphiphilic triblock copolymers based on functional poly(ethylene glycol)." Polymer Chemistry 8, no. 45 (2017): 6964–71. http://dx.doi.org/10.1039/c7py01680h.

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Given the increasing prosperity of multifunctional poly(ethylene glycol) (mf-PEG), an amphiphilic triblock copolymer, poly(ethylene glycol)-block-poly(ε-caprolactone)-block-poly(allyl glycidyl ether) (mPEG-PCL-PAGE), was synthesized by a combination of living ring-opening polymerization (ROP) and click chemistry.
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Wu, Wenjing, Weixin Wu, Mingwei Guo, Ruizhe Wang, Xuanxuan Wang, and Qinwei Gao. "Synthesis of MPEG-b-PLLA Diblock Copolymers and Their Crystallization Performance with PDLA and PLLA Composite Films." Materials 17, no. 9 (2024): 2105. http://dx.doi.org/10.3390/ma17092105.

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Methoxy poly(ethylene glycol)-block-poly(L-lactide) (MPEG-b-PLLA) has a wide range of applications in pharmaceuticals and biology, and its structure and morphology have been thoroughly studied. In the experiment, we synthesized MPEG-b-PLLA with different block lengths using the principle of ring-opening polymerization by controlling the amount of lactic acid added. The thermodynamic properties of copolymers and the crystallization properties of blends were studied separately. The crystallization kinetics of PDLA/MPEG-b-PLA and PLLA/MPEG-b-PLA composite films were studied using differential sca
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Ko, Youn Kyung, Soon Hee Kim, Hyun Jung Ha, et al. "Hybrid Type of Tissue Engineered Biodisc Using Annulus Fibrosus Seeded PLGA Scaffold and Nucleus Pulposus Seeded MPEG-PCL Hydrogel: Preliminary Study." Key Engineering Materials 342-343 (July 2007): 173–76. http://dx.doi.org/10.4028/www.scientific.net/kem.342-343.173.

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Recently, it has been studied tissue engineered technique as novel approaches for treatment of the degenerative intervertebral disc (IVD). We designed the hybrid type of IVD mimicked scaffolds with poly(lactide-co-glycolide) (PLGA) and methoxypoly(ethyleneglycol)- poly(-caprolactone) (MPEG-PCL) diblock copolymers in order to application for the tissue engineered IVD. The MPEG-PCL solutions formed a gel-to-sol phase transitions as the temperature was increasesd. MPEG-PCL diblock copolymers were prepared by ring opening polymerization, and then nucleus pulposus (NP) cell was impregnated. Also, i
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Shang, Pei, Jie Wu, Xiaoyu Shi, Zhidan Wang, Fei Song, and Shouxin Liu. "Synthesis of Thermo-Responsive Block-Graft Copolymer Based on PCL and PEG Analogs, and Preparation of Hydrogel via Click Chemistry." Polymers 11, no. 5 (2019): 765. http://dx.doi.org/10.3390/polym11050765.

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Thermo-responsive cross-linkable mPEG-b-[PCL-g-(MEO2MA-co-OEGMA)]-b-mPEG was synthesized by ring-opening polymerization (ROP) and atom transfer radical polymerization (ATRP). Then, the cross-linkable block-graft copolymer was used to prepare hydrogel via a copper-catalyzed 1,3-dipolar azide-alkyne cycloaddition reaction. The chemical structure and composition of copolymer were characterized by proton nuclear magnetic resonance (1H NMR), Fourier-transform infrared (FT-IR) and gel permeation chromatography (GPC). The self-assembly behaviors of the copolymer in aqueous solution were studied by UV
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Tapdiqov, Shamo Zokhrab. "Encapsulation and In Vitro Controlled Release of Doxycycline in Temperature-Sensitive Hydrogel Composed of Polyethyleneglycol–polypeptide (L-Alanine-co-L-Aspartate)." Journal of Biomimetics, Biomaterials and Biomedical Engineering 49 (February 2021): 119–29. http://dx.doi.org/10.4028/www.scientific.net/jbbbe.49.119.

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Doxycycline was loaded with synthesized micelles composed of methyl Poly (ethylene glycol-block-poly (L-alanine–co–L-aspartate), or mPEG–Ala–Asp, and then characterized as a drug delivery carrier. The synthesis of the temperature-sensitive mPEG–Ala–Asp block copolymer was carried out by two-step ring-opening polymerization: firstly, the mPEG reacts with L-alanine N-carboxylic anhydride, and secondly the resulting mPEG–Ala reacts with benzyl aspartate N-carboxylic anhydride. The molecular structure of the copolymers obtained was determined by FT-IR and NMR spectroscopy methods and the micelles
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Luo, Chunhui, Chongyi Chen, and Zhibo Li. "Efficient synthesis and self-assembly of hetero-grafted amphiphilic polypepide bottlebrushes." Pure and Applied Chemistry 84, no. 12 (2012): 2569–78. http://dx.doi.org/10.1351/pac-con-12-02-07.

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A new type of hetero-grafted molecular bottlebrush with polypeptide as backbone was synthesized using graft-onto strategy. Poly(γ-propargyl-L-glutamate) (PPLG) as backbone was firstly synthesized via ring-opening polymerization (ROP) of γ-propargyl-L-glutamate (PLG) N-carboxyanhydride (NCA). Next, polystyrene-N3 (PS-N3) and monomethoxy poly(ethylene glycol)-N3 (mPEG-N3) as side chains were grafted onto the PPLG backbone using copper-catalyzed click reaction, which afforded good grafting density and efficiency. Two polypeptide bottlebrushes with PS-to-mPEG molar ratio at 70/30 and 30/70 were pr
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Liu, Lian, Pei Wang, Chao Qu, Zhi Yong Wei та Min Qi. "Synthesis, Characterization and Crystallization of Poly(Ethylene Glycol)-b-Poly(ε-Caprolactone)". Advanced Materials Research 152-153 (жовтень 2010): 1665–68. http://dx.doi.org/10.4028/www.scientific.net/amr.152-153.1665.

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A family of poly(ethylene glycol)-b-poly(ε-caprolactone) (PEG-PCL) were synthesized in high yields by the ring-opening polymerization of monomethoxy-terminated poly(ethylene glycol) (mPEG) with ε-caprolactone in the presence of stannous octoate (Sn(Oct)2). Their crystallization behaviors were studied by DSC, XRD. The results illustrated that crystallization behaviors of the copolymers depended on the copolymer composition and the relative length of each block in copolymers. The melting peak of PCL block appeared gradually in the XRD patterns and DSC curves in copolymers, with increasing of the
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