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Rozprawy doktorskie na temat „MS – Multiple Sclerosis”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Foley, Peter Leonard. "Pain in multiple sclerosis." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28949.

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Background: Pain is frequently reported by people with multiple sclerosis (MS). It has been associated with decreased quality of life, psychiatric morbidity, interference with day to day activities, and frequent healthcare attendance. It has been reported by people with multiple sclerosis to be one of their most important symptoms, and available treatments are limited in their effectiveness. Despite this, our understanding of the epidemiology and mechanisms of pain in people with MS are limited. Our understanding of the interactions of central nervous system mechanisms and pain states overall

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Craig, Charles J. "Studies of immunoregulation in Multiple Sclerosis." Thesis, Queen's University Belfast, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328088.

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Evangelou, N. "Approaches to defining axonal loss in multiple sclerosis." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249538.

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Thannhauser, Jennifer, and University of Lethbridge Faculty of Education. "The psychosocial experiences of individuals diagnosed with early-onset MS." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Education, 2005, 2005. http://hdl.handle.net/10133/284.

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This qualitative study explored the psychosocial experiences of children and adolescents with early-onset multiple sclerosis. In particular, an emphasis was placed on examing peer relationships and social behaviours in relation to these experiences. MS is a chronic neurological disease primarily affecting young adults. However, a proportion of MS patients have onset during childhood and adolescence. Very little is know about the psychosocial impact of MS on these children and adolescents. In particular, youth with MS may be at risk for negative peer experiences due to their chronic illness. Pr

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Brown, Nolan J. "Localization of hemoglobin in MS cortex and its relevance to MS neuropathology." Kent State University Honors College / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1399400834.

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Rogers, Stephen. "Glycosylation of immunoglobulin G in cerebrospinal fluid and multiple sclerosis." Thesis, University of Surrey, 2001. http://epubs.surrey.ac.uk/843781/.

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The glycosylation features of CSF oligoclonal IgG, and possible changes in N-glycans of CSF IgG in multiple sclerosis (MS) were studied. After isoelectric focusing (IEF) of CSF, bands were detected using biotinylated lectins and avidin-horseradish peroxidase. Concanavalin A (Con A) binding showed that mannose exists throughout the pH range of oligoclonal IgG. Sambucus nigra antigen (SNA) bound acidic and neutral oligoclonal IgG only, suggesting that alkaline oligoclonal IgG is deficient in sialic acid. Deglycosylation of CSF IgG using peptide-N-glycosidase F suggested that the range of isoelec

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Iacobaeus, Ellen. "Establishment and applications of a multiple sclerosis biobank analysis of biomarkers and therapeutic complications in MS /." Stockholm, 2010. http://diss.kib.ki.se/2010/978-91-7409-811-2/.

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Mann, C. L. A. "The relationship of genetic polymorphisms to disease severity of multiple sclerosis." Thesis, Keele University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341244.

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The glutathione S-transferase (GST) supergene family encodes isoenzymes that appear to be critical in protection against oxidative stress. Certain GST loci are polymorphic, demonstrating alleles that are null (GSTMI/GSTT1), encode low activity variants (GSTPI), or are associated with variable inducibility (GSTM3). Interleukin-1 (IL- 1) alpha and beta are cytokines involved in recruitment of inflammatory cells, the process of inflammation, and blood-brain barrier breakdown and nerve regeneration. Polymorphisms of both GST and of a complementary interleukin-1 receptor antagonist have been associ

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Thummala, Suneel K. "Axon Initial Segment Stability in Multiple Sclerosis." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/4038.

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Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by inflammation and demyelination. In addition to these hallmark features, MS also presents with axonal pathology, which is likely responsible for the signs and symptoms of the disease. Although prominent in MS, axonal pathology is frequently considered a consequence of demyelination and not a primary event. This conclusion is consistent with demyelination inducing the loss of specific axonal domains, known as the nodes of Ranvier that are responsible for the propagation of action potentials along the

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Raask, Pontus, and Oskar Salomonsson. "Att leva med MS : En studie av självbiografier." Thesis, University of Skövde, School of Life Sciences, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-1080.

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<p>Att bli diagnostiserad med en kronisk sjukdom som Multipel Skleros (MS) kan vara förödande både fysiskt och psykiskt. Det beror mycket på hur personen med MS hanterar sin nya situation. Studier visar att det finns många sätt att hantera sjukdomen på. Detta kan sammanfattas som copingfaktorer. Syftet med denna studie var att, baserat på självbiografier, beskriva utmärkande copingfaktorer hos personer med Multipel Skleros. Studien har en kvalitativ ansats och åtta självbiografier lästes och analyserades. Resultatet visar att personer hanterar sin sjukdom på många olika sätt. Utmärkande coping

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11

Cartemo, Maria, Frida Starck, and Elin Larsson. "Hur vardagslivet gestaltar sig hos patienter med diagnosen ALS och MS : En studie gjord för att öka kunskapen och förståelsen hos sjuksköterskan." Thesis, University of Skövde, School of Life Sciences, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-1060.

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<p>Amyotrofisk lateralskleros och multipel skleros är båda neurologiska sjukdomar som orsakar fysiska begränsningar och påverkar vardagslivet. Syftet med studien var att undersöka hur vardagslivet gestaltar sig för dessa patienter. Studien baseras på en kvalitativ metod utifrån sex självbiografier och en biografi, vilket ger en insyn i patienternas egna upplevelser av hur det är att leva med ALS eller MS. Resultatet består av fyra huvudteman; Relationer, Begränsningar, Psykisk hälsa och Tankar. I samband med sjukdomen blir relationer mer betydelsefulla samtidigt som den för med sig påfrestning

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Antonazzo, Ippazio Cosimo <1988&gt. "Pharmacovigilance and Multiple Sclerosis (MS): drugs as risk factors for MS, and safety profile of drugs used in MS treatment." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amsdottorato.unibo.it/8840/1/Ippazio_Cosimo_Antonazzo_tesi.pdf.

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Several risk factors have been associated with Multiple Sclerosis onset (MSo). However, the role of previous drug exposure in MSo is far to be completely elucidated. In this intricate scenario, another important issue is represented by the safety profile of MS therapies. This thesis aimed to explore the role of drugs as possible risk factor in MSo by performing an evidence mapping of literature and a disproportionality analysis by using the FDA-Adverse Event Reporting System (FAERS) database. In the last part of the thesis, signal of Drug Induced Liver Injury (DILI) events during MS therapies

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13

Elderfield, Amber-Jayne. "Lipocortins in the central nervous system in multiple sclerosis and experimental allergic encephalomyelitis." Thesis, University of Bath, 1994. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385288.

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Brecher, R. W. "Functional characteristics of Alpha-2-Macroglobulin in normal and Multiple Sclerosis sera." Thesis, University of Sussex, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380499.

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Fox, Esther Elizabeth. "The effects of pilates based core stability training in people with MS." Thesis, University of Plymouth, 2015. http://hdl.handle.net/10026.1/3477.

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Background: People with Multiple Sclerosis experience difficulties with balance and mobility. Pilates exercises are often used to address these difficulties. Design: This was a multi-centre, double blind, block randomised, controlled trial. Eligible participants were recruited from seven UK centres. Participants were randomly allocated to either: Pilates based core stability training (Pilates), Standardised Exercise (SE) or Relaxation (placebo). All received face-to-face training sessions over a 12 week period; together with a home exercise programme. Blinded assessments were taken before trai

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16

Krökki, O. (Olga). "Multiple sclerosis in Northern Finland:epidemiological characteristics and comorbidities." Doctoral thesis, Oulun yliopisto, 2016. http://urn.fi/urn:isbn:9789526212388.

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Abstract Multiple sclerosis (MS) is the most frequent chronic inflammatory demyelinating disease of the central nervous system leading to neurological disability in young adults. Finland belongs to the high-risk areas of MS with continuously increasing of prevalence rates. In comparison to the general population, patients with MS have an increased risk of premature mortality. The extent of comorbidity rates and their role in the outcomes of MS have not been fully investigated. The aim of this thesis was to evaluate the epidemiology and survival of MS in Northern Ostrobothnia. The neurological

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17

Price, Sian Elen. "Multiple sclerosis and the genes and proteins of the central nervous system myelin." Thesis, University of Southampton, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297377.

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Basuki, Monica Anastasia Irawati. "Multiple Sclerosis and the Epstein Barr Virus: Do MS risk genes indicate an EBV signature?" Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20739.

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A debilitating degenerative autoimmune disease, Multiple Sclerosis (MS) is characterised by demyelination of neurons in the central nervous system (CNS). The exact cause of MS is unknown; though MS is thought to arise in genetically susceptible individuals, elicited by environmental factors. Around 32% of disease risk is due to genetic factors; HLA-DR has the strongest association with MS. Other MS risk genes of interest here are CD40, a member of the TNFR superfamily, transcription factors ZFP36L2, EOMES and TBX2, the transcription factor regulator ZMIZ1, and RPS6KB1, which phosphorylates rib

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Vermöhlen, Vanessa, Petra Schiller, Sabine Schickendantz, et al. "Hippotherapy for patients with multiple sclerosis: A multicenter randomized controlled trial (MS-HIPPO)." Sage, 2018. https://tud.qucosa.de/id/qucosa%3A35527.

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Background: Evidence-based complementary treatment options for multiple sclerosis (MS) are limited. Objective: To investigate the effect of hippotherapy plus standard care versus standard care alone in MS patients. Methods: A total of 70 adults with MS were recruited in five German centers and randomly allocated to the intervention group (12 weeks of hippotherapy) or the control group. Primary outcome was the change in the Berg Balance Scale (BBS) after 12 weeks, and further outcome measures included fatigue, pain, quality of life, and spasticity. Results: Covariance analysis of the primary e

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Hoffman, Kathryn Elizabeth. "Reported pain in multiple sclerosis (MS) and its relationship with affect and attention." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1446315/.

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Pain is an important part of MS symptomatology. Studies, with other pain populations, suggest distress is associated with pain. However, models of the influence of psychological factors on pain have not been carefully applied and tested with the MS population. The hypothesis was: many patients do not classify much of their sensory disturbance as pain due to their conceptual framework and this may affect the relationship between pain and distress. A model of these factors was developed for MS patients. A clinic sample of MS patients, expected to have varying degrees of subjective pain, was recr

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Weatherby, Stuart J. M. "Visual, magnetic resonance, and genetic studies of outcome in multiple sclerosis." Thesis, Keele University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368980.

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Szvetko, Attila Laszlo. "Gene Expression and Variation in Multiple Sclerosis." Thesis, Griffith University, 2009. http://hdl.handle.net/10072/366285.

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Neurological diseases are complex and difficult diseases to study. Although new approaches and therapies have been developed for other disorders such as Alzheimer’s, Epilepsy, and Parkinson’s disease, Multiple Sclerosis (MS) still remains seemingly inexorable. MS is the archetypal complex disease; it is a paradigm of debilitating neuropathology. Discounting trauma, MS is the most common chronic neurological condition resulting in disability affecting young adults. In its typical form it primarily affects the brain, spinal cord, and optic nerves and is characterised by lesions in the central ne

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Croxford, J. Ludovic. "Gene therapy for experimental allergic encephalomyelitis by delivery of inhibitory cytokines or cytokine inhibitors." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314201.

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McPheters, Justin Kade. "The role of MS patient and partner reports of couple relationship quality and depression in the physical functioning of MS patients." Related electronic resource: Current Research at SU : database of SU dissertations, recent titles available, full text:, 2008. http://wwwlib.umi.com/cr/syr/main.

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Jansson, Gertie, and Rose-Marie Eriksson. "Människors upplevelser av olika symtom i samband med depression vid sjukdomarna MS och ALS : En studie av självbiografier." Thesis, University of Skövde, School of Life Sciences, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-3049.

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<p>Vid MS och ALS förekommer depressioner i olika nyanser, vilket är viktigt för</p><p>sjuksköterskan att fånga upp tidigt och ge den omvårdnad individen behöver samt att minska lidandet. För att detta skall kunna uppnås är det viktigt att den som är sjuk känner trygghet och tillit i sin relation till sjuksköterskan. Syftet med studien var att beskriva människors upplevelser av olika symtom i samband med depression som förekommer vid MS och ALS. För att fånga upp människors upplevelser av symtom i samband med depression användes en kvalitativ metod. Data samlades in genom åtta självbiografier

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Tuke, Philip William. "Molecular techniques for the detection and characterisation of a novel retrovirus associated with multiple sclerosis." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368078.

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Duddy, Martin Edward. "The effect of INF-Î² on patterns of cytokine production and monocyte differentiation in multiple sclerosis." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322644.

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Cordingly, Kimberly Lynne. "The emerging geographies of work and identity exploring alternative employment strategies and work subjectivities of women with multiple sclerosis (MS) /." Morgantown, W. Va. : [West Virginia University Libraries], 2007. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5302.

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Thesis (Ph. D.)--West Virginia University, 2007.<br>Title from document title page. Document formatted into pages; contains x, 415 p. : col. ill. Includes abstract. Includes bibliographical references (p. 324-368).

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Dirvanskiene, Ramune. "A longitudinal study of cognitive changes in MS : dimensionality, predictors and self-perception of change." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22826.

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Background: Multiple sclerosis (MS) is a neurological disorder and the most frequent neurological cause of disability in young adults. 40-65% of MS patients experience cognitive difficulties (Bennedict et al., 2012), with problems in memory, attention and information processing speed being most frequently reported. However, visuoperceptual and language functions are much less studied in MS, but the few studies that looked into them (Vleugels, 2001; Grossman, 1995) have found prevalence of significant posterior deficits in MS. Up to today no study has investigated the domain-specificity of cogn

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Jamah, Kristina. "Hur effektivt är fingolimod vid behandling av multipel skleros?" Thesis, Linnéuniversitetet, Institutionen för naturvetenskap, NV, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-18559.

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Multipel skleros (MS) är en kronisk, neurologisk sjukdom som drabbar centrala nervsystemet (CNS). Sjukdomen är autoimmun där kroppens eget immunförsvar angriper nervvävnaden, framför allt myelin, och därefter uppstår en inflammatorisk reaktion. Nerverna i det centrala nervsystemet påverkar många olika funktioner och eftersom myelinet som omsluter nervfibrerna blir inflammerat på olika ställen, både i hjärnan och i ryggmärgen, uppkommer olika typer av symptom. Symptomen för MS kan skilja sig mycket från en individ till en annan, och från skov till skov. Om McDonald-kriterierna uppfylls, som byg

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Haase, Rocco, Jennifer S. Kullmann, and Tjalf Ziemssen. "Therapy satisfaction and adherence in patients with relapsing–remitting multiple sclerosis: the THEPA-MS survey." Sage, 2016. https://tud.qucosa.de/id/qucosa%3A35540.

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Background: Improved clinical effectiveness and therefore positive modification of multiple sclerosis (MS) with basic therapy can be achieved by long-term regular intake of drugs as prescribed but investigations have shown that a high percentage of patients do not take their medications as prescribed. Objectives: We assessed the satisfaction and adherence of patients with MS with their current disease-modifying treatment under clinical practice conditions. We compared different facets of satisfaction as well as their internal relationship and identified predictors in an exploratory manner. Met

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Amini, Alikani Amineh, and Sofia Nygren. "Upplevelse, livskvalitet och stöd från sjuksköterskor : en litteraturstudie om fatigue hos personer med MS." Thesis, Högskolan i Gävle, Avdelningen för hälso- och vårdvetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-11823.

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Syfte: Var att öka förståelsen för upplevelsen av fatigue hos personer med MS och fatigues inverkan på livskvaliteten samt hur sjuksköterskan kan stödja och hjälpa personer med MS i vardagen. Metod: Litteraturstudie med deskriptiv design. Artiklarna (n=15) söktes fram i databaserna Medline via PubMed och Cinahl samt manuell sökning via referenslistor, sex stycken kvalitativa, åtta kvantitativa och en med en kombination av båda ansatser. Resultat: Det framkom att fatigue hos personer med MS var ett osynligt symtom som påverkade kroppen, led till begränsningar i vardagen, förvärrade andra symtom

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Acosta, Crystal May R. "Antigenic induction of nerve growth factor (NGF) in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS)." Bentham Science, 2013. http://hdl.handle.net/1993/23504.

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Nerve growth factor (NGF) represents a new therapeutic strategy for multiple sclerosis (MS) because of its immunomodulatory and neuroprotective activity. To analyze changes in NGF expression experimental autoimmune encephalomyelitis (EAE) was induced in Lewis rats. In the dorsal root ganglia (DRG) of animals with EAE, NGF mRNA and protein increased between 18 - 24 days post induction (dpi) during complete neurological recovery. In the spinal cord (SC) of animals with EAE, NGF mRNA and protein expression increased at 15 dpi and 12 dpi, respectively, to reduce EAE-induced disability. We iden

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Huss, David J. "Effector Th1 cells demonstrate self-regulation in a mouse model of Multiple Sclerosis." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1305118647.

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Norgren, Martin, and Johan Hägglund. "Upplevelser, påverkan på vardagen och egenvård : - En litteraturstudie om MS-relaterad fatigue." Thesis, Högskolan i Gävle, Avdelningen för hälso- och vårdvetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-13411.

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Syfte: Litteraturstudiens syfte var att beskriva upplevelsen av MS-relaterad fatigue, hur den påverkade vardagen och val av egenvårdsstrategier. Metod: Beskrivande litteraturstudie. Resultatdelen innehåller 15 st vetenskapliga artiklar, varav 8 st har en kvantitativ ansats, 5 st har en kvalitativ ansats och 2 st har båda ansatserna. Artiklarna söktes i databaserna PubMed och Cinahl och genom manuell sökning. Resultat: MS-relaterad fatigue var en unik och individuell upplevelse. Fatigue hade en multidimensionell och handikappande inverkan på vardagen, som berörde såväl fysiska, psykiska, social

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Sundin-Röstberg, Lotta, and Åse Zachrisson. "Multipel Skleros och Graviditet : Omvårdnad och stöd till kvinnor med MS före, under och efter graviditet." Thesis, Högskolan i Gävle, Avdelningen för hälso- och vårdvetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-27459.

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Syfte: Var att beskriva MS-patienters erfarenheter före, under och efter graviditet. Hur MS-sjuksköterskan kan stötta och vägleda MS-patienter i frågor som kan uppstå före, under och efter graviditeten utifrån evidensbaserad kunskap. Vidare granskades den metodologiska aspekten gällande urvalet/urvalskriterierna i litteraturstudiens utvalda artiklar. Metod: Litteraturstudien hade en beskrivande design. Artikelsökning gjordes i databaserna Pubmed, PsycInfo, och Cinahl samt manuell sökning utifrån de granskade artiklarna i litteraturstudien. Artiklarna (n=18) var 1 antal kvalitativa, och 17 anta

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Blomberg, Carolina. "Intrathecal and Systemic Complement Activation Studies of Multiple Sclerosis and Guillan-Barré Syndrome." Thesis, University of Kalmar, School of Pure and Applied Natural Sciences, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hik:diva-2032.

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<p>Both Multiple Sclerosis (MS) and Guillan-Barré syndrome (GBS) are neurological inflammatory demyelinating autoimmune diseases, with a probable antibody contribution. Complement proteins in both MS and GBS does play a role in inflammation and demyelination at pathogenesis, according to earlier scientific evidence. The aim of this examination project work was to investigate systemic and intrathecal complement activation in MS and GBS, to gain further knowledge that might be useful for development of future therapeutics targeting immune responses during those diseases. An additional aim was to

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Davis, William Henry. "Development of a high-throughput genotyping assay for detection of functional polymorphisms involved in homocysteine metabolism and the methylation process implicated in multiple sclerosis." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/95457.

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Thesis (MMedSc)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: The aetiology of multiple sclerosis (MS) remains largely unknown due to the multifactorial nature of disease susceptibility determined by both environmental and genetic factors. Progress has been made in identifying the genetic component of MS , as well as the possible interactions with the environment. In this study single nucleotide polymorphisms (SNPs) in the FTO (rs9939609, Intron 1 T>A), MTR (rs1805087, 2756 A>G), MTRR (rs1801394, 66 A>G), MTHFR (rs1801133, 677 C>T and rs1801131, 1298 A>C) and COMT (rs46

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Sjöberg, Susanne. "The Ytterby mine - A historical review and an evaluation of its suggested spatial coupling to multiple sclerosis (MS)." Thesis, Stockholms universitet, Institutionen för geologiska vetenskaper, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-84521.

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The Ytterby mine is located on Resarö island in the Stockholm archipelago. Mainly feldspars but also quartz were historically quarried in the mine, which is also the place of discovery of seven rare earth elements (REE). During the cold war era, the mine shaft was used as a diesel and jet fuel deposit for the Swedish Armed Forces. Recently, a spatial coupling between multiple sclerosis (MS), a chronic neurodegenerative disease in the central nervous system, prevalence and the quarry has been suggested. Previous studies show that adverse neurological health effects are associated with oral inta

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Wynia, Klaske. "The Multiple Sclerosis Impact Profile (MSIP), an ICF-based outcome measure for disability and disability perception in MS development and psychometric testing /." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/.

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Söderholm, Simon. "The Complex Genetics of Multiple Sclerosis : A preliminary study of MS-associated SNPs prior to a larger genotyping project." Thesis, Linköpings universitet, Institutionen för fysik, kemi och biologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-129423.

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Biomedical research have been revolutionized by recent technological advances, both in the fields of molecular biology and computer science, turning the biomolecular and genetic research into “big data science”. One of the main objectives have been to improve our understanding of complex human diseases. Among those diseases, multiple sclerosis (MS) is considered as one of the most common. MS is a chronic autoimmune disease that cause inflammation and damage to the central nervous system. In this study, a set of bioinformatics analyses have been conducted on SNP data, as an initial step to gain

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Mickens, Melody N. "TODO EN LA FAMILIA: EXAMINING THE RELATIONSHIPS AMONG MS IMPAIRMENTS, FAMILY NEEDS, AND CAREGIVER MENTAL HEALTH IN GUADALAJARA, MEXICO." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3930.

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Individuals with multiple sclerosis (MS), especially those living in Latin America, often require assistance from family caregivers throughout the duration of disease. Previous findings suggest that family caregivers may experience positive and negative effects from providing care to individuals with MS, but few studies have examined the impact of MS caregiving on caregivers from Latin America. The current study examined the relationships between MS impairments (functional, neurological, cognitive, behavioral and emotional), unmet family needs (household, informational, financial, social suppo

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Gillisdotter, Anna. "Att delta i en Fatigue Management kurs – upplevelser från personer med MS-fatigue." Thesis, Luleå tekniska universitet, Hälsa och rehabilitering, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-67521.

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Syftet med denna studie var att beskriva hur personer med MS-fatigue upplever upplägg och innehåll i FM-kursen, samt vilken betydelse de upplever att kursen haft för deras möjligheter att hantera sin MS-fatigue i vardagen. En kvalitativ metod med semistrukturerade intervjuer användes. Data är analyserad med riktad kvalitativ innehållsanalys. Resultatet visade att deltagarna upplevde att kursen var lärorik men ansträngande. Samtidigt gav kursen dem kunskap och strategier för att hantera MS-fatigue i vardagen. Huvudfyndet anses vara hur deltagarna upplever kursen stöttat dem hantera MS-fatiguen

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Douglas, Clint. "The impact of pain on the quality of life of people with multiple sclerosis." Thesis, Queensland University of Technology, 2007. https://eprints.qut.edu.au/16523/1/Clint_Douglas_Thesis.pdf.

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This thesis was concerned with determining the scope, nature and impact of pain on quality of life (QOL) among a community-based sample of people with multiple sclerosis (MS). An analysis of the research literature on pain in MS reveals that pain is a significant problem which has historically been underinvestigated and is currently poorly understood. The vast majority of the published literature consists of prevalence studies, descriptive research and clinical reports. Where available, empirical data are often limited by methodological and analytical problems such that substantive conclusions

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Douglas, Clint. "The impact of pain on the quality of life of people with multiple sclerosis." Queensland University of Technology, 2007. http://eprints.qut.edu.au/16523/.

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This thesis was concerned with determining the scope, nature and impact of pain on quality of life (QOL) among a community-based sample of people with multiple sclerosis (MS). An analysis of the research literature on pain in MS reveals that pain is a significant problem which has historically been underinvestigated and is currently poorly understood. The vast majority of the published literature consists of prevalence studies, descriptive research and clinical reports. Where available, empirical data are often limited by methodological and analytical problems such that substantive conclusions

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GUERRIERI, SIMONE. "The visual pathway as a platform to assess demyelination and neurodegeneration in multiple sclerosis: the paradigms of acute optic neuritis and progressive course." Doctoral thesis, Università Vita-Salute San Raffaele, 2022. http://hdl.handle.net/20.500.11768/128352.

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Background and aims: full-field visual evoked potentials (ff-VEPs) are used as an indicator of demyelination, with multifocal technique (mf-VEPs) allowing to assess conduction for separate portions of the visual field. Optical coherence tomography (OCT) is used instead as a marker of neuro-axonal loss. We explored the value of these techniques and their relations with clinical measures in multiple sclerosis (MS)-related acute optic neuritis (aON) and in progressive MS (PMS). Material and methods: aON substudy - 48 MS or clinically isolated syndrome (CIS) patients with a first aON episode in th

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Herbert, Estelle Penelope. "Magnetic Resonance Imaging and Biochemical markers to assess disability in female subjects with Multiple Sclerosis." Thesis, Cape Peninsula University of Technology, 2016. http://hdl.handle.net/20.500.11838/2404.

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Thesis (M.Sc (Radiography))--Cape Peninsula University of Technology, 2016.<br>Multiple sclerosis (MS) affects the central nervous system (CNS) and is characterized by multiple demyelinating lesions. It is in this context that a need arises for reliable biomarkers such as Magnetic Resonance Imaging (MRI), which could lead to the early diagnosis and therapeutic intervention when maximum potential impact is possible. This study examines the impact of MRI as a marker and the sequences that give the best images to aid in evaluation of disease progression (which can indirectly be seen as

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Conway, Devon S. "Long-Term Benefits of Early Treatment in Multiple Sclerosis: An Investigation Utilizing a Novel Data Collection Technique." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1307635721.

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Poggiali, Davide. "Postprocessing Neuroimaging methods in MRI and PET/MRI with applications to Multiple Sclerosis and other Neurological diseases." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3421919.

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Many non-invasive imaging instruments have been developed in the last 40 years, allowing to obtain images of the interior human body while the patient is still alive. In the contest of Neurology studies, imaging system as CT, MRI, SPECT or PET allows to obtain biomarkers useful to quantitatively distinguish between healthy and unhealthy subjects, evaluate the staging of a Neurological illness in a patient, evaluate the efficacy of a treatment, explore the causes of the illness. In this work MRI and PET imaging system introduced from scratch, going from reconstruction from raw data to state-of

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Kaur, Inderpreet. "Delivering a remote exercise program embedded with behaviour change theory to persons with multiple sclerosis (MS): a randomised feasibility trial." Thesis, Kaur, Inderpreet (2021) Delivering a remote exercise program embedded with behaviour change theory to persons with multiple sclerosis (MS): a randomised feasibility trial. Masters by Research thesis, Murdoch University, 2021. https://researchrepository.murdoch.edu.au/id/eprint/61392/.

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Introduction: Multiple sclerosis (MS) is a chronic, autoimmune, and demyelinating disease of the central nervous system. Exercise has shown to be an effective treatment; however, those with MS often do not adhere to the recommended exercise guidelines. Our study investigated the feasibility of a remote exercise program embedded with behaviour change to increase exercise participation (primary outcome) and adherence among persons with MS and improve MS symptomatology and quality of life (secondary outcomes). Methods: Thirty-six adults with mild to moderate MS were stratified according to previo

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