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Artykuły w czasopismach na temat "Oral tumours"

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Munawar Ali Baloch, Ikramuddin Ujjan, and Mehnaz Munawar. "Demography and Histopathological presentations of oral and maxillo-facial region tumours in Jamshoro, Pakistan." JMMC 9, no. 2 (2019): 81–84. http://dx.doi.org/10.62118/jmmc.v9i2.89.

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Introduction: Oral and Pharyngeal cancers are the sixth most common cancer globally. In developing countries, the annual incidence of oral cancer is around 275,000 cases while 130,300 cases of pharyngeal cancers excluding naso-pharynx. Salivary glands tumors are rare accounting for less than 5 % of tumors of head and neck region. The annual incidence of these tumors is 0.05 to 2 cases per 100,000 populations. Majority (over two third quarters) of salivary gland tumors occurs in the parotid glands of which most of them (2/3rd) of them are benign in nature. While most common parotid gland’s beni
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Renuga, S., NS Sahana, G. Suganya, and Meghashyama Kulkarni. "An enigmatic combined tumour of oral malignant melanoma and oral squamous cell carcinoma – A rare case report." Journal of Oral and Maxillofacial Pathology 28, no. 2 (2024): 343–46. http://dx.doi.org/10.4103/jomfp.jomfp_330_22.

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Abstract Combined tumours are those composed of two benign tumours or a benign and malignant tumour or two malignant tumours occurring within the same tumour population. The incidence of combined tumours is very rare. Due to the rarity of these tumours, their biological behaviour remains unlashed. Incisional biopsy of a 48 years old female patient with single, diffuse tumour mass in the oral cavity showed combined tumour or collision tumour of malignant melanoma and squamous cell carcinoma. This was confirmed with immunohistochemistry study. The incidence of combined tumour of malignant melano
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Bloor, Claire. "Oral tumours." Veterinary Nurse 10, no. 1 (2019): 26–32. http://dx.doi.org/10.12968/vetn.2019.10.1.26.

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Masamatti, Smita S., and Alka V. Gosavi. "Benign Soft Tissue Lesions of Oral Cavity: A Histopathological Study." JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES 06, no. 3 (2016): 88–90. http://dx.doi.org/10.58739/jcbs/v06i3.4.

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Background: To describe the histopathological types and frequency of the most common benign tumours of oral cavity reporting to the government referral hospital at Miraj in Maharashtra state. Materials and Methods: A retrospective analysis was made of the five year records of reports of oral biop-sy samples of patients maintained by the department of pathology. The data obtained was compiled for age, gender, site of the lesion and the histopathology features of the lesions. Results: Seventy of the 642 biopsy samples of the oral lesions reported in this five year period were categorised as beni
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Islam, Md Amirul, M. Ahmed Hossain, Sabrina Binte Rahman, Md Ali Kawser, and Md Shamsur Rahman. "Maxillofacial tumors and tumor-like lesions : a retrospective analysis." Update Dental College Journal 8, no. 1 (2018): 22–28. http://dx.doi.org/10.3329/updcj.v8i1.38408.

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Background: This paper reviews the types, prevalence and demographic distribution of maxillofacial tumors, cysts and tumor-like lesions in a Bangladeshiteaching Hospital.An observational descriptive study (January’ 2014 to December’ 2016) was performed at Oral and Maxillofacial Surgery depart- ment, Dental Unit,TMSS Medical College and Hospital. This study presents 55 cases of maxillofacial tumour & tumour like lesions collected over 3 years at a tertiary oral care centre in Bogra, Bangla- desh.Objectives:To find out the distribution & pattern of maxillofacial tumours and to find out t
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Behra, Biswadeep, S. Vairamuthu, Natesan Pazhanivel, Periyasamy Jalantha, and Ganne Venkata Sudhakar Rao. "Histological and Immunohistochemical Features of Pulmonary Metastatic Oral Melanoma in a Labrador dog." Indian Journal of Veterinary Sciences & Biotechnology 18, no. 5 (2022): 119–22. http://dx.doi.org/10.48165/ijvsbt.18.5.24.

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Melanoma is a malignant tumour that originates from melanocytes. It has been reported in human beings as well as in many domesticated animal species (Reddy et al., 1998), and wild terrestrial and marine animals. Melanomas are the most commonly diagnosed malignant tumours in the oral cavity of canines (Goldschmidt, 1985; Faramade et al., 2017). Gingiva is the most common site for canine oral malignant melanoma (OMM) but other parts like palatine, labile or buccal mucosa also act as the sites of origin (Delverdier et al., 1991). It is generally an aggressive tumour, often locally invasive, and f
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'Afifah Khairunnnisa, Rienda, Sinar Yani, and Cristiani Nadya Pramasari. "Prevalence of Patients with Oral Cavity Tumours at Hospital Abdoel Wahab Sjahranie Samarinda 2016-2020." DENTA 16, no. 1 (2022): 21–26. http://dx.doi.org/10.30649/denta.v16i1.4.

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Background: Tumour is an uncontrolled swelling of tissue. Tumour caused by uncontrolled proliferation abnormal tissue and cell. Based on the nature of the tumour, there are two types of tumours, that is benign tumour and malignant tumour. The malignant tumour can cause death while benign tumour only aggravate the surrounding tissue.The high incidence of tumors in various countries, including Indonesia, rarely finds research on the prevalence of oral tumors, especially in East Kalimantan, especially the capital city of Samarinda. Objective: This research is to find out the incidence of oral cav
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Nelke, Kamil, Maciej Janeczek, Edyta Pasicka, et al. "The Occurrence of a Rare Mandibular Retromolar Triangle Schwannoma and Its Differentiation from Other Rare and Atypical Oral Cavity Tumours." Applied Sciences 14, no. 9 (2024): 3924. http://dx.doi.org/10.3390/app14093924.

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Cone-beam computed tomography (CBCT) remains the diagnostic modality of choice. The involvement of the cortical bone and adjacent teeth can be easily established via CBCT. Magnetic resonance can be helpful in the estimation of any other soft-tissue tumour spread within this anatomical area. The soft, hard-tissue, or mixed aetiology of tumours requires a differential diagnosis and accurate evaluation. If such pathologies arise, an adequate biopsy or incisional biopsy is essential to evaluate the type of tumour histopathologically. The occurrence of some neural tumours in the oral cavity is rare
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Mustafa, Wan Mahadzir, Noraini N. N. Yunus, Lau Shin Hin, and Eleena Yusof. "Oral and maxillofacial tumours in paediatric and adolescent patients presenting to Hospital Kuala Lumpur in a 10 year period." Malaysian Journal of Oral and Maxillofacial Surgery 15, no. 1 (2017): 17–22. https://doi.org/10.4103/mjoms_2017151_17.

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The purpose of this study was to document the pattern of paediatric tumours treated in Department of Oral and Maxillofacial Surgery and Paediatric Dentistry Hospital Kuala Lumpur, during a 10-year period. Data of patients were retrieved from the operation theatre book from the year 2000 to 2009. The collection of data included gender, age, location, histopathology and treatment of the tumour. The patients' ages ranged from 4 to 18 years. There was an equal sex distribution. The majority of patients were Malays (53.3%, n=32) followed by Chinese (30.0%, n=18) and the remaining patients were Indi
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Fransson, B., C. Preston, and D. Reynolds. "Crescentic osteotomy for resection of oral tumours in four do." Veterinary and Comparative Orthopaedics and Traumatology 22, no. 05 (2009): 412–16. http://dx.doi.org/10.3415/vcot-08-09-0080.

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SummaryRim resection of mandibular tumours and a simplified technique using a biradial osteotomy blade for maxillary tumours in dogs has not previously been described. The medical records and radiographs of dogs with mandibular (n = 3) or maxillary (n = 1) tumours resected using crescentic osteotomies were reviewed. The owners of two of the dogs reported excellent outcomes without any long-term complications or tumour recurrence. The goal of this study was to describe the surgical technique for performing a crescentic osteotomy for resection of maxillary and mandibular tumours. This technique
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Rozprawy doktorskie na temat "Oral tumours"

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Aljorani, Lateef Essa. "The expression and role of Migration Stimulating Factor (MSF) in oral tumours." Thesis, University of Dundee, 2012. https://discovery.dundee.ac.uk/en/studentTheses/941cc539-6f7b-48a8-a764-4e3de2abc714.

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Migration Stimulating Factor (MSF) is an oncofoetal protein which is constitutively produced by both epithelial and stromal cells during foetal development, not expressed by the majority of their normal adult counterparts, but re-expressed during pathological processes such as cancer and wound healing. Scotland has the highest occurrence of oral cancers in the UK; the incidence is still increasing, but patient survival remains very poor. The expression of MSF in oral tumours has not been previously reported. The aims of this study were: • To determine the effects of MSF on the migration of ora
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Robinson, Conrad Maxwell. "The role of transcription factor AP-1 and gelatinases in oral carcinogenesis and their regulation by transforming growth factor beta." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299443.

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Boland, Paul William. "Morphometric analysis of data inherent in examination by magnetic resonance imaging : importance to natural history, prognosis and disease staging of squamous carcinoma of the oral cavity." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:934e1e5a-24db-40ab-ab54-5e58901a9c2a.

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Magnetic resonance imaging plays an important yet underutilized role in determining the natural history and prognosis of oral carcinoma. Depth of tumour invasion is an emergent factor in the oral cancer literature. However, problems exist with the definition of cut-points suitable for inclusion in TNM staging criteria. Statistical methodology represents a possible explanation but is underexplored. In this work, a review of the depth of invasion literature is conducted with emphasis on statistical technique. As well, statistical simulation is used to explore the implications of the of the minim
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Rodríguez, Freixinós Víctor. "Implicación prónostica de la infección por virus del papiloma himano en tumores de orofaringe y cavidad oral localmente avanzados e irresecables." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/456246.

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En la última década, la incidencia de los tumores escamosos de cabeza y cuello relacionados con el virus del Papiloma Humano (HPV), principalmente en los tumores de orofaringe, ha aumentado considerablemente, siendo considerados una entidad clínica asociada a características etiológicas, clínicas y pronósticas diferenciadas del subgrupo de tumores HPV negativos. Los tumores HPV positivos, comparados con los tumores HPV negativos, presentan mejor pronóstico sin embargo el impacto pronóstico de HPV en localizaciones diferentes a la orofaringe no está claramente establecido. Diferentes estrategia
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Lau, Sze-lok Alfred, and 劉思樂. "Evidence-based practice in oral and maxillofacial surgery." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B45007755.

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Al-Damouk, Jawdet Dakhel. "Malnutrition and experimental oral carcinogenesis." Thesis, University of Glasgow, 1988. http://theses.gla.ac.uk/2731/.

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The work was undertaken to examine the effects of nutritional deficiencies on cancer induction. Two of the most common and widely distributed nutrients, iron and folic acid, were examined to evaluate the effects of their deficiency on animals. The Syrian golden hamster was the animal model for all experimental work. In the first part of the study an attempt was made to induce iron deficiency in young adult male hamsters by feeding iron deficient diet coupled with repeated venesection of 1.5ml every two weeks. Following twelve weeks on this regime a superficial biopsy was taken, on week 13, fro
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Junior, Ophir Ribeiro. "Estudo da terapêutica cirúrgica dos tumores odontogênicos queratocísticos associados ou não à síndrome do carcinoma nevóide de células basais e análise do tempo livre de recorrência." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/23/23149/tde-13092012-120559/.

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O tumor odontogênico queratocístico (TOQ) é uma neoplasia cística benigna originada de remanescentes epiteliais da odontogênese, que se destaca pela alta recorrência e eventual associação com a síndrome do carcinoma nevóide de células basais (SCNCB). O presente estudo buscou responder questionamentos relacionados à sua terapêutica cirúrgica e suprir a carência de pesquisas atuais sobre as lesões associadas à SCNCB, que são ainda mais recorrentes, analisando uma amostra formada por 40 TOQs primários. As variáveis de interesse determinaram grupos amostrais, que receberam análise dos tempos livre
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Lau, Sze-lok Alfred. "Evidence-based practice in oral and maxillofacial surgery /." View the Table of Contents & Abstract, 2005. http://sunzi.lib.hku.hk/hkuto/record/B32222154.

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Oliver, Richard John. "Quantification of cell cycle markers in oral precancer." Thesis, University of Glasgow, 1998. http://theses.gla.ac.uk/2691/.

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The overall aims of the studies were to obtain objective measures of oral precancerous lesions based upon studies of the cell cycle and to investigate these parameters as possible prognostic indicators with regard to malignant transformation of these lesions. The majority of the precancerous lesions in the present study were dysplastic. These are the lesions which cause the greatest concern clinically with regard to malignant transformation. The first part of the study investigated the S-phase, growth fraction and the relationship of these to each other and with the degree of dysplasia with th
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Prelec, Jelena. "Oral second primary tumour risk predictors : clinical factors and loss of heterozygosity." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/49979.

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Oral squamous cell carcinoma (SCC) has a poor survival rate mainly due to late stage diagnosis and the high risk of developing second primary tumours (SPTs). Risk factors associated with progression of primary oral premalignant lesions (OPLs) to SCC have been validated; however, little research has been done on the risk predictors of SPTs. The objective of this thesis was to identify the demographic, clinicopathological and molecular risk factors associated with oral SPTs as well as those associated with second oral premalignant lesion (SOPL) progression to an oral SPT. From a cohort of the Or
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Książki na temat "Oral tumours"

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ed, Henk J. M., and Langdon J. D. ed, eds. Malignant tumours of the oral cavity. Edward Arnold, 1985.

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Kee, Hai Ho, Sai Loh Hong, Singapore Ministry of Health, Singapore Cancer Society, World Health Organization, and International Union against Cancer, eds. The first International Congress on oral cancer and jaw tumours, Singapore, 9th-14th November 1987. Professional Postgraduate Services, 1988.

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Lucas, R. B. Lucas's Pathology of tumors of the oral tissues. 5th ed. Churchill Livingstone, 1998.

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Harris, Michael K. Oral cancer: Causes, diagnosis, and treatment. Nova Science Publishers, 2010.

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D, Saranath, ed. Contemporary issues in oral cancer. Oxford University Press, 2000.

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Thomson, Peter James. Oral precancer: Diagnosis and management of potentially malignant disorders. Wiley-Blackwell, 2012.

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Reichart, P. Odontogenic tumors and allied lesions. Quintessence Pub., 2004.

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Kawakami, Toshiyuki. Cell differentiation of neoplastic cells originating in the oral and craniofacial regions. Nova Science, 2008.

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W, Baxter Prudence, and James Jacqueline, eds. The maxillary sinus and its dental implications. Wright, 1993.

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Odontogenic Tumours. Quintessence Publishing (IL), 2004.

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Części książek na temat "Oral tumours"

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Lucas, R. B., and J. W. Eveson. "Tumours of the Oral Tissues 1. Odontogenic Tumours." In Atlas of Oral Pathology. Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-5580-6_10.

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Bahadur, Sudhir. "Residual/Recurrent Tumours." In Management of Oral Cancers. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-6499-4_11.

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Lucas, R. B., and J. W. Eveson. "Tumours of the Oral Tissues 2. Non-odontogenic Tumours." In Atlas of Oral Pathology. Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-5580-6_11.

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Chehal, Hardeep. "Histopathology of Odontogenic Tumours of the Jawbones." In Oral Histology and Oral Histopathology. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-77481-2_21.

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Shah, Anjan Kumar. "Benign Odontogenic Tumours." In Oral and Maxillofacial Surgery for the Clinician. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_28.

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AbstractOdontogenic tumours of the maxillofacial region presents with a large number of histologic patterns and are derived from the primordial tooth forming tissues. They can occur most commonly in mandible and maxilla. The recent WHO classification helps in developing the appropriate treatment plan and categorizing the tumours. The present chapter deals with various benign odontogenic tumours with their clinical presentation and management in detail, based on clinical scenarios.
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Lucas, R. B., and J. W. Eveson. "The Salivary Glands 2. Tumours." In Atlas of Oral Pathology. Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-5580-6_8.

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Dhillon, Ramindar S., and James W. Fairley. "Tumours of the oral cavity." In Multiple-choice Questions in Otolaryngology. Palgrave Macmillan UK, 1989. http://dx.doi.org/10.1007/978-1-349-10805-3_267.

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Ghaly, Ghaly A. "Tumours of the oral cavity." In Logan Turner's Diseases of the Nose, Throat and Ear, 12th ed. CRC Press, 2024. http://dx.doi.org/10.1201/9780429430268-28.

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Sharma, Rohit K. "Oral Cancer Surgery." In Operative Surgery for Head and Neck Tumours. CRC Press, 2021. http://dx.doi.org/10.1201/9780367430139-8.

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Firth, Norman. "Other Malignant Salivary Gland Tumours." In Oral Medicine - A Clinical Guide. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-36797-7_45.

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Streszczenia konferencji na temat "Oral tumours"

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Milošević-Marković, Maja, Milan Petrović, Drago Jelovac, Igor Đorđević, and Svetlana Jovanović. "Patients with oral cancer in the healthcare system of Serbia." In Proceedings of the International Congress Public Health - Achievements and Challenges. Institute of Public Health of Serbia "Dr Milan Jovanović Batut", 2024. http://dx.doi.org/10.5937/batutphco24065m.

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Background: Patients with oral cancer have a significantly impaired quality of life and in Serbia they are among the ten most common tumours in male population. Methods and Objectives: The aim of this study was to determine the recognition of this population group in the health care system in Serbia. During the June 2024 a review and analysis of relevant health policies, strategies, programs and other documents related to health in the Republic of Serbia, was undertaken. Results: According to the Law on Health Insurance, these patients have the right to full coverage of costs for examinations
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Sun, Guangping, Jingchun Huang, and Zhongyan Li. "The Clinical Analysis on the postoperative complications of the Elderly Patients with the Oral and Maxillofacial Tumours." In 2015 International Forum on Bioinformatics and Medical Engineering. Atlantis Press, 2015. http://dx.doi.org/10.2991/bme-15.2015.14.

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Bitenc Zore, Sara, and Robert Šifrer. "Narrow-Band Imaging – Clinical Application in Otorhinolaryngology." In Socratic Lectures 8. University of Lubljana Press, 2023. http://dx.doi.org/10.55295/psl.2023.i10.

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Narrow-Band Imaging (NBI) is an optical endoscopic technique using optic filters to select two wavebands from a white light source and revealing mucosal and submucosal vascular patterns. NBI endoscopy is implemented to detect various lesions of the nasal and oral cavity, oropharynx and hypopharynx, and larynx; for finding bleeding vessel in recurrent epistaxis, for more precise tissue biopsy, in the diagnostics of synchronous cancers, for tumours of unknown origin, in defining surgical margins, inflammation and for follow-up of oncologic patients. According to lesion area in otorhinolaryngolog
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Lima, Isabela Ferrari, Mariana do Nascimento Borba, Samara Maria da Silva, Anna Beatriz Arruda Barroso de Moraes, and Irani de Farias Cunha Junior. "What is the prevalence of tumors that cause the loss of bone structures in the face?" In II Seven International Education Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/iieducationcongress-027.

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INTRODUCTION: Tumors are a tissue growth disorder, benign tumors are usually well defined, while malignant tumors can spread and lead to death. In some cases, the first indication of the presence of a bone tumor is a pathological fracture, especially thosethat have bone involvement. OBJECTIVE: To identify the prevalence and incidence of tumors that cause loss of facial bone structures, in addition to analyzing the efficacy of surgical treatment in cases of tumors that destroy facial bone structures.METHODOLOGY: This is a literature review in which the search for articles was carried out in the
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Crisan, Bogdan, Mihaela Baciut, Liana Crisan, et al. "Treatment of oral soft tissues benign tumors using laser." In Fifth International Conference on Lasers in Medicine, edited by Carmen Todea, Adrian G. Podoleanu, and Virgil-Florin Duma. SPIE, 2014. http://dx.doi.org/10.1117/12.2043231.

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Rogatkin, Dmitrii A., Pavel Y. Polyakov, Oleg A. Bychenkov, and Elena A. Stepanenko. "Noninvasive fluorescence diagnostics in radiotherapy of mucosal oral tumors." In Saratov Fall Meeting 2001, edited by Valery V. Tuchin. SPIE, 2002. http://dx.doi.org/10.1117/12.475595.

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Balster, S., A. Teiler, T. Neumayer, R. Sader, T. Stöver, and S. Ghanaati. "Synchronous second tumors in case of panendoscopy with evidence of oral carcinoma at a certified tumor center." In Abstract- und Posterband – 90. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Digitalisierung in der HNO-Heilkunde. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1685957.

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Musulin, Jelena, Daniel Štifanić, Ana Zulijani, and Zlatan Car. "SEMANTIC SEGMENTATION OF ORAL SQUAMOUS CELL CARCINOMA ON EPITHELLIAL AND STROMAL TISSUE." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.194m.

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Oral cancer (OC) is among the top ten cancers worlwide, with more than 90% being squamous cell carcinoma. Despite diagnostic and therapeutic development in OC patients’ mortality and morbidity rates remain high with no advancement in the last 50 years. Development of diagnostic tools in identifying pre-cancer lesions and detecting early-stage OC might contribute to minimal invasive treatment/surgery therapy, improving prognosis and survival rates, and maintaining a high quality of life of patients. For this reason, Artificial Intelligence (AI) algorithms are widely used as a computational aid
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Kacorzyk, Urszula. "Results of Primary Treatment and Salvage Treatment in the Management of Patients with Non-Squamous Cell Malignant Tumors of the Sinonasal Region: Single Institution Experience." In 5th International Conference on Dentistry and Oral Health. United Research Forum, 2025. https://doi.org/10.51219/urforum.2025.urszula-kacorzyk.

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Pretti, Marco, Mariana Boroni, Nicole Scherer, et al. "Metastasis of HPV-negative oral cavity tumors: an in silico study." In IV International Symposium on Immunobiologicals & VII Seminário Anual Científico e Tecnológico. Instituto de Tecnologia em Imunobiológicos, 2019. http://dx.doi.org/10.35259/isi.sact.2019_32824.

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Raporty organizacyjne na temat "Oral tumours"

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Reisfeld, Ralph A. An Oral DNA Vaccine Encoding Endoglin Eradicates Breast Tumors by Blocking Their Blood Supply. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada455983.

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Reisfeld, Ralph A. An Oral DNA Vaccine Encoding Endoglin Eradicates Breast Tumors by Blocking Their Blood Supply. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada474671.

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Suriyaphol, Gunnaporn. Study the gene expression of E-cadherin, syndecan1, matrix metalloproteinases-2, -7, -9, -14 and tissue inhibitors of metalloproteinases-1 and -2 in canine oral melanoma. Chulalongkorn University, 2015. https://doi.org/10.58837/chula.res.2015.80.

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The objectives of this study were to 1.) select the suitable reference genes for quantitative real-time polymerse chain reaction in the most common canine oral cancers: oral melanoma (OM) and oral squamous cell carcinoma (OSCC), 2.) study the gene expression of E-cadherin (CDH1), syndecan 1 (SDC1), matrix metalloproteinases-2, -7, -9, -14 (MMP2, MMP7, MMP9, MMP14) and tissue inhibitors of metalloproteinases-1 and -2 (TIMP1, TIMP2) in canine OM at the mRNA level and study the CDH1, SDC1 and Ki-67 protein expression by immunohistochemistry, and 3.) study the association of gene expression and th
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