Zaloguj się

Gotowe bibliografie tematyczne / Pulsatile drug delivery system / Rozprawy doktorskie

Kliknij ten link, aby zobaczyć inne rodzaje publikacji na ten temat: Pulsatile drug delivery system.

Rozprawy doktorskie na temat „Pulsatile drug delivery system”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

Utwórz poprawne odniesienie w stylach APA, MLA, Chicago, Harvard i wielu innych

Wybierz rodzaj źródła:

Sprawdź 50 najlepszych rozpraw doktorskich naukowych na temat „Pulsatile drug delivery system”.

Przycisk „Dodaj do bibliografii” jest dostępny obok każdej pracy w bibliografii. Użyj go – a my automatycznie utworzymy odniesienie bibliograficzne do wybranej pracy w stylu cytowania, którego potrzebujesz: APA, MLA, Harvard, Chicago, Vancouver itp.

Możesz również pobrać pełny tekst publikacji naukowej w formacie „.pdf” i przeczytać adnotację do pracy online, jeśli odpowiednie parametry są dostępne w metadanych.

Przeglądaj rozprawy doktorskie z różnych dziedzin i twórz odpowiednie bibliografie.

1

Kwok, Connie Sau-Kuen. "Development of self-assembled molecular structures on polymeric surfaces and their applications as ultrasonically responsive barrier coatings for on-demand, pulsatile drug delivery /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/7999.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

2

Gandhi, Swapnilkumar J. "Barrier-mediated pulsatile release." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/1601.

Pełny tekst źródła

Streszczenie:

Solutes are often most efficiently deployed in discrete pulses, for example in the delivery of herbicides or drugs. Manual application of each pulse can be labor-intensive, automated application of each pulse can be capital intensive, and both are often costly and impractical. Barrier-Mediated Pulsatile Release (BMPR) systems offer a materials-based alternative for automated pulsatile drug delivery, without pumps, power supplies, or complex circuitry. While earlier materials-based approaches such as delayed-release microcapsules are limited to two or three pulses due to the independent nature

Style APA, Harvard, Vancouver, ISO itp.

3

Berton, Damiano <1994&gt. "Microfluidic production of drug delivery system." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/19484.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

4

Leach, Jeffrey Harold. "Magnetic Targeted Drug Delivery." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/31261.

Pełny tekst źródła

Streszczenie:

Methods of guiding magnetic particles in a controlled fashion through the arterial system in vivo using external magnetic fields are explored. Included are discussions of applications, magnetic field properties needed to allow guiding based on particle characteristics, hemodynamic forces, the uniformity of field and gradients, variable tissue characteristics, and imaging techniques employed to view these particles while in transport. These factors influence the type of magnetic guidance system that is needed for an effective drug delivery system. This thesis reviews past magnetic drug deliv

Style APA, Harvard, Vancouver, ISO itp.

5

Ho, Duc Hong Linh 1978. "Packaging for a drug delivery microelectromechanical system." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/30262.

Pełny tekst źródła

Streszczenie:

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.<br>Includes bibliographical references (p. 52-55).<br>Local drug delivery is a fast expanding field, and has been a center of attention for researchers in medicine in the last decade. Its advantages over systemic drug delivery are clear in cancer therapy, with localized tumors. A silicon microelectromechanical drug delivery device was fabricated for the purpose of delivering chemotherapeutic agents such-as carmustine, a potent brain cancer drug, directly to the site of the tumor. Limitations

Style APA, Harvard, Vancouver, ISO itp.

6

Dyer, Robert J. (Robert Joseph) 1977. "Needle-less injection system for drug delivery." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/89388.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

7

Bright, Anne M. "Towards an improved ocular drug delivery system." Thesis, Aston University, 1992. http://publications.aston.ac.uk/9801/.

Pełny tekst źródła

Streszczenie:

The ultimate aim of this project was to design new biomaterials which will improve the efficiency of ocular drug delivery systems. Initially, it was necessary to review the information available on the nature of the tear fluid and its relationship with the eye. An extensive survey of the relevant literature was made. There is a common belief in the literature that the ocular glycoprotein, mucin, plays an important role in tear film stability, and furthermore, that it exists as an adherent layer covering the corneal surface. If this belief is true, the muco-corneal interaction provides the idea

Style APA, Harvard, Vancouver, ISO itp.

8

Birudaraj, Kondamraj. "Transbuccal drug delivery: In vitro characterization of transport pathway of buspirone and bioadhesive drug delivery system." Scholarly Commons, 2001. https://scholarlycommons.pacific.edu/uop_etds/2733.

Pełny tekst źródła

Streszczenie:

The objective of this research was to investigate two important aspects of buccal drug delivery, transport and mucoadhesion. Buspirone was chosen as a model drug for the in vitro buccal transport studies, polyvinyl alcohol and sodium alginate polymer blends were prepared to investigate the mucoadhesive properties through a Lewis acid-base approach and finally, the effect of formulation factors on the force of mucoadhesion, surface energy parameters, release rate and flux was studied. In vitro permeation studies were conducted to investigate the buccal transport pathway of buspirone. Mathematic

Style APA, Harvard, Vancouver, ISO itp.

9

Warrilow, Philip A. D. "Polyamine conjugates as a potential drug delivery system." Thesis, University of Leicester, 1997. http://hdl.handle.net/2381/30012.

Pełny tekst źródła

Streszczenie:

The work in this thesis has covered three main topics; i) cytotoxic polyamine-conjugates ii) radiation protection polyamine-conjugates iii) polyamine conjugates which probe cellular uptake and DNA binding. The synthesis of these conjugates employed selective protection/deprotection steps, taking advantage of the BOC protecting groups regioselectivity of primary over secondary amines when reacting with naturally occurring polyamines. After promising in vitro and in vivo results of the original spermidine-chlorambucil synthesised by Wheelhouse (1990), attempts were made to improve this compound.

Style APA, Harvard, Vancouver, ISO itp.

10

Bosworth, Mark Erwin. "Evaluation of liposomes as a drug delivery system /." Ann Arbor : University Microfilms International, 1987. http://www.gbv.de/dms/bs/toc/016141032.pdf.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

11

Saeed, Aram Omer. "Toward advanced modular drug and gene delivery system." Thesis, University of Nottingham, 2010. http://eprints.nottingham.ac.uk/27632/.

Pełny tekst źródła

Streszczenie:

In chapter two, the development of new a nanoparticulate carrier system for gene delivery was described. The new nanocarrier consists of a blend matrix formed by a poly (lactic-eo-glycolic acid) (PLGA) and Poly(ethylene glycol) bis (3-aminopropyl) terminated (also known as JeffamineTM). Nanopartic1es were formulated based on a 50:50 weight ratio of PLGA:Jeffamine using a modified emulsification-solvent diffusion technique. The potential of these blended matrix nanoparticles for encapsulation efficiency of Calf Thymus DNA and release profile were also studied. The achieved encapsulation efficie

Style APA, Harvard, Vancouver, ISO itp.

12

Blackwell, Lisa Jane. "Sporopollenin exines as a novel drug delivery system." Thesis, University of Hull, 2007. http://hydra.hull.ac.uk/resources/hull:7162.

Pełny tekst źródła

Streszczenie:

Microcapsules are fast becoming the most successful delivery systems for the oral delivery of drugs and food additives. Since many drugs are proteins and are destroyed in acidic conditions, microcapsules offer protection against the harsh environment of the gastrointestinal (GI) tract. Although the use of microcapsules achieves controlled release of the inner material, many synthetically designed microcapsules lack consistency in their size and morphology. The outer coat (exine) of plant pollen grains and spores is composed of the material sporopollenin. Sporopollenin exines (25µm diameter) we

Style APA, Harvard, Vancouver, ISO itp.

13

Lee, Yan Sim. "The development of controlled-chemotherapy drug delivery system." Thesis, University of Bath, 2009. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512304.

Pełny tekst źródła

Streszczenie:

The aim of this thesis was to develop biodegradable devices loaded with chemotherapy drug. The system is targeted for advanced ovarian cancer treatment through the intraperitoneal (IP) route of administration. Polylactide-co-glycolide (PLGA) was selected as the model biodegradable polymer to produce drug-loaded microsphere, hollow and solid fibres. Copolymer PLGA with three different lactic:glycolic acids ratios; 50:50, 65:35 and 75:25 were used in order to compare their drug loading capacities and in vitro drug release profiles. Cisplatin, a cytotoxic drug with proven activity against ovarian

Style APA, Harvard, Vancouver, ISO itp.

14

Salvage, Jonathan Peter. "A novel phosphorylcholine-based nanoparticulate drug delivery system." Thesis, University of Brighton, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499068.

Pełny tekst źródła

Streszczenie:

Phosphorylcholine (PC) based materials have been shown to have increased biocompatibility when compared to more established bio-implantable materials. This has been attributed to the ability of PC to mimic the cell lipid bilayer membrane, resulting in reduced protein adhesion and cellular interaction / activation. PC research has previously focused on the areas of contact lens formulation and medical device coating. This project sought to harness the biomimetic properties of PC to develop novel systems for drug delivery, with the emphasis being focused on microparticulate drug delivery.

Style APA, Harvard, Vancouver, ISO itp.

15

MODICA, DE MOHAC Laura. "Novel Drug Delivery System for Treatment-Resistant Schizophrenia." Doctoral thesis, Università degli Studi di Palermo, 2021. http://hdl.handle.net/10447/478483.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

16

Nguyen, Thi Lam Uyen Nguyen Centre for Advanced Macromolecular Design Faculty of Engineering UNSW. "Crosslinked microspheres as drug delivery system for liver cancer." Publisher:University of New South Wales. Centre for Advanced Macromolecular Design, 2008. http://handle.unsw.edu.au/1959.4/41528.

Pełny tekst źródła

Streszczenie:

It has been demonstrated that 1,25 dihydroxy vitamin D3 (1,25 (OH)2VD3) can inhibit the proliferation of cancer cells including colorectal and hepatocellular cells which are mainly responsible for liver cancer. However, the use of 1, 25 (OH)2VD3 is hampered due to the development of hypercalcaemia. Current treatment using hepatic arterial delivery of drug solution is inconvenient since repetitive invasive treatments are required. This work aims to tackle this problem by utilizing crosslinked microspheres prepared by suspension polymerization as a carrier to control the release of 1, 25 (OH)2VD

Style APA, Harvard, Vancouver, ISO itp.

17

Roxhed, Niclas. "A Fully Integrated Microneedle-based Transdermal Drug Delivery System." Doctoral thesis, Stockholm : Kungliga Tekniska högskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4484.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

18

Freddi, Matthew James. "Intra-articular depot forming drug delivery system for osteoarthritis." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12662/.

Pełny tekst źródła

Streszczenie:

Osteoarthritis (OA) is a chronic degenerative disease of the joint. Current treatments for this disease (such as glucocorticoid steroids) aim to reduce pain and increase mobility. Intra-articular injection is used in OA as treatment can be targeted to affected joints only. There is currently a lack of sustained release formulations for intra-articular injection. The aim of this thesis was to produce and characterise an injectable intra-articular drug delivery system capable of providing delivery of the steroid dexamethasone phosphate (DXMP) over 3 months. This would be an injectable hydrogel t

Style APA, Harvard, Vancouver, ISO itp.

19

Goettsche, Thorsten [Verfasser], Roland [Akademischer Betreuer] Zengerle, and Gerald A. [Akademischer Betreuer] Urban. "IntelliDrug - controlled, oral drug delivery system as tooth implant." Freiburg : Universität, 2016. http://d-nb.info/1128574195/34.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

20

Taimur, Muhammad <1992&gt. "Drug delivery system for the treatment of burn injuries." Master's Degree Thesis, Università Ca' Foscari Venezia, 2020. http://hdl.handle.net/10579/17961.

Pełny tekst źródła

Streszczenie:

With the advancements in medicine, various solutions have been proposed to treat skin burns. But serious burns interesting a large area of body surface remain a major cause of subsequent infections because of several factors, such as poor penetration of drugs through skin barrier, availability of bacterial nutrients in the burned area, destruction of the vascular supply to the burned skin. All these factors jointly make burns vulnerable to infection. To overcome these factors and other limitations of conventional burn injury treatments, we have proposed a formulation. In the present study, we

Style APA, Harvard, Vancouver, ISO itp.

21

Babu, Kavitha Mary Vadakkel. "The Development of a Novel Controlled Release Drug Delivery System." The University of Waikato, 2007. http://hdl.handle.net/10289/2590.

Pełny tekst źródła

Streszczenie:

The aim of this research was to formulate, characterise and assess the feasibility of a novel drug delivery system known as the in situ gelling matrix (ISGM) where a hydrophilic polymer is suspended in a non-aqueous solvent that converts into a gel when injected subcutaneously or intramuscularly thus giving a controlled release matrix for a drug. Although the concept has been patented with claims that this kind of drug delivery is achievable in theory for a wide variety of candidate substances, actual formulation studies for making a commercially viable product for this technology are complet

Style APA, Harvard, Vancouver, ISO itp.

22

Hemond, Brian D. (Brian David Thomson). "A Lorentz-force actuated controllable needle-free drug delivery system." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/37201.

Pełny tekst źródła

Streszczenie:

Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2004; and, (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, February 2006.<br>Includes bibliographical references (leaves 89-90).<br>The advantages of delivering injections via needle-free methods are numerous. However, conventional methods for needle-free injection lack sufficient control over depth of penetration and shape of injection. Thus, a needle-free injector was designed, constructed, and tested, using a controllable li

Style APA, Harvard, Vancouver, ISO itp.

23

Venugopal, Balaji. "Preclinical evaluation of a novel drug delivery system for cisplatin." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/4198/.

Pełny tekst źródła

Streszczenie:

The aim of this body of work was to characterise a novel cisplatin drug delivery system and to develop new tools based on biophotonic imaging that could be used to enhance studies of drug delivery in vivo. Cucurbiturils (CB) are macrocycles which are formed by acid catalysed condensation of glycoluril and formaldehyde. The internal cavity of CB[7] encapsulates a single molecule of cisplatin and the hypothesis was that encapsulation would reduce thiol degradation of the drug. Drug sensitivity studies in vitro with the cisplatin-sensitive human ovarian cancer cell line, A2780, and a cisplatin-re

Style APA, Harvard, Vancouver, ISO itp.

24

Gilbert, Helena Rosalind Petra. "Bioresponsive polymer-protection conjugates as a unimolecular drug delivery system." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55685/.

Pełny tekst źródła

Streszczenie:

PEGylation has become very popular for the generation of nanomedicines with improved protein delivery properties, despite its lack of biodegradability. Researchers usually try to maximise retained protein activity during PEGylation. However, this proof of principle study aimed to create an inactive peptide or enzyme product, using a biodegradable polymer, that would elicit minimal activity/non-specific toxicity on administration. Following triggered site-specific degradation of the polymer, the hypothesis was that protein activity could be slowly regenerated in the general circulation or local

Style APA, Harvard, Vancouver, ISO itp.

25

Abdulrazzaq, Fadi. "Aquasomes as a drug delivery system for proteins and peptides." Thesis, Aston University, 2016. http://publications.aston.ac.uk/30080/.

Pełny tekst źródła

Streszczenie:

Aquasomes are nanocarrier systems consist of three distinctive layers; an inner core, a polyhydroxy carbohydrate layer and an outer layer of an API (Kossovsky et al., 1991). Aquasomes have a unique structure and ability to carry active molecules through a non-covalent bounding and provide superior stability, especially for proteins and peptides (Masatoshi and Yongning, 1998; Kim and Kim, 2002; Khopade et al., 2002). Different core and coating materials were used to prepare aquasomes under different conditions to investigate the relationship between preparation conditions and loading efficiency

Style APA, Harvard, Vancouver, ISO itp.

26

Rodriguez, Lidia Betsabe. "Controlled Release System for Localized and Sustained Drug Delivery Applications." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1365107103.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

27

Beier, Anne Mette. "Chitosan microparticles as a drug delivery system for protein vaccines /." [Cph.] : Pharmexa A/S : Department of Pharmaceutics, The Royal Danish School of Pharmacy, 2002. http://www.dfh.dk/phd/defences/annemettebeier.htm.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

28

BRUNO, GIACOMO. "Leveraging nanochannels for a remotely controllable implantable drug delivery system." Doctoral thesis, Politecnico di Torino, 2017. http://hdl.handle.net/11583/2676478.

Pełny tekst źródła

Streszczenie:

This work is focused on the research on how to leverage nanochannels in the eld of Nanomedicine. More speci cally the study of different diffusion regimes at the nanoscale thanks to the close collaboration between the Politecnico di Torino, Turin, Italy, and the Methodist Hospital Research Institute, Houston, Texas. The therapeutics ow through nanochannels can be tightly controlled by several factors such as channels dimension, channel polarity, solution ionic strength just to name a few. The major advantage of this nanotechnology is that the drug ow results to be linear over time and pract

Style APA, Harvard, Vancouver, ISO itp.

29

Cecchin, Denis. "Study and characterization of drug delivery system in regenerative medicine." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3422729.

Pełny tekst źródła

Streszczenie:

Abstract Drug delivery system (DDS) technology is particularly promising to improve the in vivo efficiency of active molecules. Moreover, it is possible to stabilize and prolong the half life at biologically active molecules, thus prolonging the in vitro activity. DDS's can be used either for the delivery of anticancer drug but also for the controlled release of growth factors essential for the tissue engineering. In this work DDS’s have been investigate to develop new targeted anticancer drug or to control the release of growth factor for tissue engineering. In the first case polymer conju

Style APA, Harvard, Vancouver, ISO itp.

30

Shojaei, Amir Hossein. "Buccal mucoadhesive delivery system of acyclovir." Scholarly Commons, 1997. https://scholarlycommons.pacific.edu/uop_etds/2626.

Pełny tekst źródła

Streszczenie:

Novel buccal mucoadhesive copolymers of acrylic acid (AA) and poly (ethylene glycol) monomethylether monomethacrylate (PEGMM), (P(AA-co-PEG)), were designed, synthesized, and characterized for systemic delivery of acyclovir across the buccal mucosa. To achieve spontaneous intimate contact between polymer and buccal mucosa, the surface properties of P(AA-co-PEG) were optimized for buccal adhesion by varying the composition of the copolymers. It was found that the mole ratio of the repeat units of PEG, ethylene glycol, to AA is of great importance for mucoadhesion. ATR-FTIR studies revealed that

Style APA, Harvard, Vancouver, ISO itp.

31

Yang, Xiaojuan. "Development of Nanoparticle Systems for Therapeutic Drug Delivery." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1248972068.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

32

Falahat, Rana. "Tunable Nano-Delivery System for Cancer Treatment: A New Approach for Targeted Localized Drug Delivery." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6234.

Pełny tekst źródła

Streszczenie:

Localized drug delivery systems have been widely studied as potential replacements for conventional chemotherapy with the capability of providing sustained and controlled drug release in specific targeted sites. They offer numerous benefits over conventional chemotherapy such as enhancing the stability of embedded drugs and preserving their anticancer activity, providing sustained and controlled drug release in the tumor site, reducing toxicity and diminishing subsequent side effects, minimizing the drug loss, averting the need for frequent administrations, and minimizing the cost of therapy.

Style APA, Harvard, Vancouver, ISO itp.

33

Chinnakavanam, Sundararaj Sharath Kumar. "Development of a Multilayered Association Polymer System for Sequential Drug Delivery." UKnowledge, 2013. http://uknowledge.uky.edu/cbme_etds/13.

Pełny tekst źródła

Streszczenie:

As all the physiological processes in our body are controlled by multiple biomolecules, comprehensive treatment of certain disease conditions may be more effectively achieved by administration of more than one type of drug. Thus, the primary objective of this research was to develop a multilayered, polymer-based system for sequential delivery of multiple drugs. This particular device was designed aimed at the treatment of periodontitis, a highly prevalent oral inflammatory disease that affects 90% of the world population. This condition is caused by bacterial biofilm on the teeth, resulting in

Style APA, Harvard, Vancouver, ISO itp.

34

Wong, Ling Wai. "Molecular delivery system based on the nanoporous zeolite microstructures /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?BIEN%202006%20WONG.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

35

Lee, Wang Wang. "Factors affecting drug release and absorption from a novel oral delayed release drug delivery system." Thesis, Durham University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269886.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

36

Venthoye, M. Geraldine. "Characterisation of an amorphous dry powder aerosol system." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265519.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

37

Hawley, Ann Elizabeth. "The uptake of nanospheres by the lymphatic system." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307765.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

38

Zeng, Jianming. "Constrained crystallization and depletion in the polymer medium for transdermal drug delivery system." Diss., Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/5102.

Pełny tekst źródła

Streszczenie:

Transdermal drug delivery systems (TDS) are pharmaceutical devices that are designed to deliver specific drugs to the human body by diffusion through skin. The TDS effectiveness suffers from crystallization in the patch when they are kept in storage for more than two years. It has been reported that there are two types of crystals in the patch: needle and aggregate, and growth of drug crystals in TDS generally occurs only in the middle third of the polymer layer. In our study, fluorescence microscopy, EDS (SEM) and Raman microspectroscopy were used to further characterize the crystals. The res

Style APA, Harvard, Vancouver, ISO itp.

39

Svirskis, Darren. "Development of a novel drug delivery system based on conducting polymers." Thesis, University of Auckland, 2010. http://hdl.handle.net/2292/6568.

Pełny tekst źródła

Streszczenie:

Controlled release systems offer advantages over conventional therapies by maintaining drug concentrations at therapeutically desired levels whilst simultaneously improving compliance. Intrinsically Conducting Polymers (ICP) are organic materials that have electrical, magnetic and optical properties usually associated with metals, whilst retaining the advantageous mechanical properties and ease of processing usually associated with polymers. A novel drug delivery system, based on the ICP polypyrrole (PPy), has been developed to provide for the controlled release of risperidone. Due to t

Style APA, Harvard, Vancouver, ISO itp.

40

Cheng, Erik Ho Yan. "Combination of hydrogel and liposomes as a responsive drug delivery system." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ29374.pdf.

Pełny tekst źródła

Style APA, Harvard, Vancouver, ISO itp.

41

NASCIMENTO, Débora Dolores Souza da Silva. "Obtenção de drug delivery system carbamazepina-zif-8 visando liberação prolongada." Universidade Federal de Pernambuco, 2017. https://repositorio.ufpe.br/handle/123456789/25939.

Pełny tekst źródła

Streszczenie:

Submitted by Fernanda Rodrigues de Lima (fernanda.rlima@ufpe.br) on 2018-08-20T20:30:39Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Débora Dolores Nascimento.pdf: 3594688 bytes, checksum: cdf7df39006953035bd1e74095fb8d37 (MD5)<br>Approved for entry into archive by Alice Araujo (alice.caraujo@ufpe.br) on 2018-08-28T18:14:14Z (GMT) No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Débora Dolores Nascimento.pdf: 3594688 bytes, checksum: cdf7df39006953035bd1e74095fb8d37 (MD5)<br>M

Style APA, Harvard, Vancouver, ISO itp.

42

Al, Thaher Yazan. "Antimicrobial drug LbL-assembled delivery system for orthopaedic nanocomposite bone cements." Thesis, Cardiff University, 2018. http://orca.cf.ac.uk/112718/.

Pełny tekst źródła

Streszczenie:

Total joint replacement (TJR) is commonly used for the treatment of end stage arthritis. The use of Poly-methylmethacrylate (PMMA) bone cement is a gold standard TJR, where it is frequently used for local delivery of antibiotics to provide prophylaxis from prosthetic joint infections (PJI). Currently used antibiotic loaded bone cements have many limitations, including burst release which fall below inhibitory levels leading to the selection of antibiotic resistant strains. This study aims to provide a controlled release for antimicrobial agents from bone cement to provide prophylaxis from post

Style APA, Harvard, Vancouver, ISO itp.

43

Lin, Hong-Liang, and 林宏糧. "Development and Evaluation of Formulation for Oral Pulsatile Drug Delivery System." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/46688091558431422750.

Pełny tekst źródła

Streszczenie:

博士<br>臺北醫學大學<br>藥學研究所<br>96<br>This study attempted to develop the single-unit reservoir systems of tablet (doxazosin mesylate) and pellet (propranolol hydrochloride) dosage form with pulsatile–release patterm. In single unit tablet system, this study attempted to characterize the influence of core and coating formulations on the release profiles for a pulsatile drug delivery system activated by membrane rupture based on three core tablet formulations (A-core: HPMC 50+4000 cps, B-core: E10M, and C-core: K100M) coated with various thicknesses of a semipermeable ethylcellulose membrane plasticiz

Style APA, Harvard, Vancouver, ISO itp.

44

Qu, Beibei. "A Study on the Periodic Precipitation Phenomena and Their Application to Drug Delivery Systems." Thesis, 2012. http://hdl.handle.net/1807/44080.

Pełny tekst źródła

Streszczenie:

The main objective of this research was to better understand, predict and control of the periodic precipitation process and to apply such programmed periodic precipitation to the design of a pulsatile delivery system. In the first part of this study, a generalized model taking into account both nucleation, particle growth, and ripening process was refined and solved under various new concentration boundary conditions not previously investigated. The results clearly delineate the key differences between boundary conditions of infinite versus finite supply of inner electrolyte. When the inner el

Style APA, Harvard, Vancouver, ISO itp.

45

Hoosain, Famida Ghulam. "A dual oral intestinal film for pulsatile release of a mood stabilizing agent in the treatment of schizoaffective disorder." Thesis, 2016. http://hdl.handle.net/10539/21403.

Pełny tekst źródła

Streszczenie:

A thesis submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Doctor of Philosophy Johannesburg, 2016<br>Oral drug delivery is acknowledged by many as the idyllic method of drug delivery due to its versatility and convenience of administration. Nevertheless, the bioavailability of drugs delivered via the oral route remains disputed. Classically, conventional marketed drug delivery systems release drugs in inconstant and unpredictable manners, leading to sub-therapeutic and in some cases toxic drug doses

Style APA, Harvard, Vancouver, ISO itp.

46

Thitinan, Sumalee. "Development of multiple dose platforms for oral drug delivery." Thesis, 2011. http://hdl.handle.net/2152/ETD-UT-2011-12-4529.

Pełny tekst źródła

Streszczenie:

Multiple dose regimens are frequently required to optimize therapy; however, such therapy is frequently undermined by poor patient adherence. In fact, patient adherence is inversely related to the number of doses a patient is asked to take each drug. Consequently, great efforts are under way to develop drug delivery systems that are able to release drugs over an extended time interval; this could offer considerable benefits including reducing administration frequency. This dissertation describes multiple dose platforms designed to deliver a variety of drugs as a single oral administration a

Style APA, Harvard, Vancouver, ISO itp.

47

Kuo, Chan-Hsuan, and 郭蟬瑄. "Estimation the transdermal drug delivery efficiency of the handheld liquid drug delivery system." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/kfnx33.

Pełny tekst źródła

Streszczenie:

碩士<br>國立臺灣科技大學<br>醫學工程研究所<br>106<br>Drug permeation through the skin is usually limited by the stratum corneum in epidermis. In this study, the efficacy of a hand-held liquid drug delivery system for transdermal drug delivery will be evaluated. GNT GoldMedTM handheld liquid drug delivery system is a needle-free and low pressure of gas-powered injection system which can be used for transdermal biomaterials or drugs delivery. This study is mainly to assess the gas pressure, gas inflation time, flux and penetration depth of transdermal drug delivery by using this hand-held liquid drug delivery sy

Style APA, Harvard, Vancouver, ISO itp.

48

Zhang, Mengjue. "Microfluidic system development for drug delivery." Thesis, 2016. http://hdl.handle.net/2440/102614.

Pełny tekst źródła

Streszczenie:

Development and application of a microfluidic system for generating drug delivery carriers are investigated in this research. Various types of microfluidic devices are designed and fabricated for peptide nanotubes, liposome vesicles and double emulsions formation. The microfluidic system offers a better control over the formation process of all three drug delivery carriers. Comparing to traditional methods such as bulk mixing, the process efficiency, size and size distribution of the final products are significantly improved. The results generated show that tuning the flow rate ratios between

Style APA, Harvard, Vancouver, ISO itp.

49

(9188927), seyedalireza abootorabi. "COMPUTATIONAL FLUID DYNAMICS FOR MODELING AND SIMULATION OF INTRAOCULAR DRUG DELIVERY AND WALL SHEAR STRESS IN PULSATILE FLOW." Thesis, 2020.

Znajdź pełny tekst źródła

Streszczenie:

<div>The thesis includes two application studies of computational ﬂuid dynamics. The ﬁrst is new and eﬃcient drug delivery to the posterior part of the eye, a growing health necessity worldwide. Current treatment of eye diseases, such as age related macular degeneration (AMD), relies on repeated intravitreal injections of drug-containing solutions. Such a drug delivery has signiﬁcant drawbacks, including short drug life, vital medical service, and high medical costs. In this study, we explore a new approach of controlled drug delivery by introducing unique porous implants. Computational</div><

Style APA, Harvard, Vancouver, ISO itp.

50

Abootorabi, Seyedalireza. "Computational Fluid Dynamics for Modeling and Simulation of Intraocular Drug Delivery and Wall Shear Stress in Pulsatile Flow." Thesis, 2020. http://hdl.handle.net/1805/23571.

Pełny tekst źródła

Streszczenie:

Indiana University-Purdue University Indianapolis (IUPUI)<br>The thesis includes two application studies of computational fluid dynamics. The first is new and efficient drug delivery to the posterior part of the eye, a growing health necessity worldwide. Current treatment of eye diseases, such as age-related macular degeneration (AMD), relies on repeated intravitreal injections of drug-containing solutions. Such a drug delivery has significant cant drawbacks, including short drug life, vital medical service, and high medical costs. In this study, we explore a new approach of controlled drug

Style APA, Harvard, Vancouver, ISO itp.

Oferujemy zniżki na wszystkie plany premium dla autorów, których prace zostały uwzględnione w tematycznych zestawieniach literatury. Skontaktuj się z nami, aby uzyskać unikalny kod promocyjny!