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Artykuły w czasopismach na temat "Steroid receptors"

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Baker, ME. "Recent insights into the origins of adrenal and sex steroid receptors." Journal of Molecular Endocrinology 28, no. 3 (2002): 149–52. http://dx.doi.org/10.1677/jme.0.0280149.

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The recent cloning by Thornton (2001) of estrogen, progesterone and corticoid receptors from lamprey provides important insights into the early evolution of adrenal and sex steroid receptors and an opportunity to elucidate the ancient steroids that regulated gene transcription. Inclusion of lamprey sequences in a steroid receptor phylogeny indicates that the estrogen receptor is the most ancient of these receptors, followed by the progesterone receptor and the corticoid receptor. Thornton proposed that estradiol was the earliest of the steroids to activate a steroid receptor. An alternative hy
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Baker, ME. "Adrenal and sex steroid receptor evolution: environmental implications." Journal of Molecular Endocrinology 26, no. 2 (2001): 119–25. http://dx.doi.org/10.1677/jme.0.0260119.

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The nuclear receptor family responds to a diverse group of ligands, including steroids, retinoids, thyroid hormone, prostaglandins and fatty acids. Previous sequence analyses of adrenal and sex steroid receptors indicate that they form a clade separate from other nuclear receptors. However, the relationships of adrenal and sex steroid receptors to each other and to their ancestors are not fully understood. We have used new information from androgen, estrogen, mineralocorticoid and progesterone receptors in fish to better resolve the phylogeny of adrenal and sex steroid receptors. Sequence dive
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Marcinkowska, Ewa, and Antoni Wiedłocha. "Steroid signal transduction activated at the cell membrane: from plants to animals." Acta Biochimica Polonica 49, no. 3 (2002): 735–45. http://dx.doi.org/10.18388/abp.2002_3782.

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Steroid hormones in plants and in animals are very important for physiological and developmental regulation. In animals steroid hormones are recognized by nuclear receptors, which transcriptionally regulate specific target genes following binding of the ligand. In addition, numerous rapid effects generated by steroids appear to be mediated by a mechanism not depending on the activation of nuclear receptors. Although the existence of separate membrane receptors was postulated many years ago and hundreds of reports supporting this hypothesis have been published, no animal membrane steroid recept
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Wiseman, Helen, and Rosanna Duffy. "Steroids, steroid receptors and disease." Trends in Molecular Medicine 7, no. 4 (2001): 146–47. http://dx.doi.org/10.1016/s1471-4914(01)01978-5.

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Hammes, Stephen R., and Ellis R. Levin. "Extranuclear Steroid Receptors: Nature and Actions." Endocrine Reviews 28, no. 7 (2007): 726–41. http://dx.doi.org/10.1210/er.2007-0022.

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Rapid effects of steroid hormones result from the actions of specific receptors localized most often to the plasma membrane. Fast-acting membrane-initiated steroid signaling (MISS) 1leads to the modification of existing proteins and cell behaviors. Rapid steroid-triggered signaling through calcium, amine release, and kinase activation also impacts the regulation of gene expression by steroids, sometimes requiring integration with nuclear steroid receptor function. In this and other ways, the integration of all steroid actions in the cell coordinates outcomes such as cell fate, proliferation, d
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Adcock, I. M., S. J. Lane, C. R. Brown, M. J. Peters, T. H. Lee, and P. J. Barnes. "Differences in binding of glucocorticoid receptor to DNA in steroid-resistant asthma." Journal of Immunology 154, no. 7 (1995): 3500–3505. http://dx.doi.org/10.4049/jimmunol.154.7.3500.

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Abstract Although glucocorticosteroids are a very effective treatment for asthma and other chronic inflammatory diseases, a small proportion of patients are resistant to their therapeutic effects. The molecular mechanism for this steroid resistance is unclear. Steroid resistance cannot be explained by pharmacokinetic mechanisms, by a defect in the binding of steroids to glucocorticoid receptors, nor by defective nuclear translocation of this receptor, thereby suggesting that the molecular abnormality lies distal to nuclear translocation. We examined the ability of nuclear translocated glucocor
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Godowski, Paul J., and Didier Picard. "Steroid receptors." Biochemical Pharmacology 38, no. 19 (1989): 3135–43. http://dx.doi.org/10.1016/0006-2952(89)90605-9.

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Levin, Ellis R. "Extranuclear estrogen receptor's roles in physiology: lessons from mouse models." American Journal of Physiology-Endocrinology and Metabolism 307, no. 2 (2014): E133—E140. http://dx.doi.org/10.1152/ajpendo.00626.2013.

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Steroid receptors exist and function in multiple compartments of cells in most organs. Although the functions and nature of some of these receptors is being defined, important aspects of receptor localization and signaling to physiology and pathophysiology have been identified. In particular, extranuclear sex steroid receptors have been found in many normal cells and in epithelial tumors, where they enact signal transduction that impacts both nongenomic and genomic functions. Here, I focus on the progress made in understanding the roles of extranuclear estrogen receptors (ER) in physiology and
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Mukudai, Shigeyuki, Ken Ichi Matsuda, Takeshi Nishio, et al. "Differential Responses to Steroid Hormones in Fibroblasts From the Vocal Fold, Trachea, and Esophagus." Endocrinology 156, no. 3 (2015): 1000–1009. http://dx.doi.org/10.1210/en.2014-1605.

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Abstract There is accumulating evidence that fibroblasts are target cells for steroids such as sex hormones and corticoids. The characteristics of fibroblasts vary among tissues and organs. Our aim in this study is to examine differences in responses to steroid hormones among fibroblasts from different cervicothoracic regions. We compared the actions of steroid hormones on cultured fibroblasts from the vocal folds, which are considered to be the primary target of steroid hormones, and the trachea and esophagus in adult male rats. Expression of steroid hormone receptors (androgen receptor, estr
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Knutti, Darko, Adesh Kaul, and Anastasia Kralli. "A Tissue-Specific Coactivator of Steroid Receptors, Identified in a Functional Genetic Screen." Molecular and Cellular Biology 20, no. 7 (2000): 2411–22. http://dx.doi.org/10.1128/mcb.20.7.2411-2422.2000.

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ABSTRACT Steroid receptors mediate responses to lipophilic hormones in a tissue- and ligand-specific manner. To identify nonreceptor proteins that confer specificity or regulate steroid signaling, we screened a human cDNA library in a steroid-responsive yeast strain. One of the identified cDNAs, isolated in the screen as ligand effect modulator 6, showed no homology to yeast or Caenorhabditis elegansproteins but high similarity to the recently described mouse coactivator PGC-1 and was accordingly termed hPGC-1. The hPGC-1 DNA encodes a nuclear protein that is expressed in a tissue-specific man
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Rozprawy doktorskie na temat "Steroid receptors"

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Malouitre, Sylvanie Désirée Marie. "Glucocorticoid receptor function, interactions with oestrogen receptors and a steroid inhibitor." Thesis, Queen Mary, University of London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413737.

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Brady, P. "A thermodynamic approach to steroid-based receptors." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596861.

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Chapter 1 begins with a brief overview of molecular recognition and then presents a review of recently developed methods for lead generation and the synthesis of self-defining host molecules. Chapter 2 describes a strategy for the synthesis of functionally active molecules which combines advantageous features of some of the methods described in Chapter 1. Relevant literature and precedents are then introduced followed by a discussion of theoretical considerations. In Chapter 3, after an introduction to the use of cholate building blocks in supramolecular chemistry, the synthesis of the new ste
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Hazell, Georgina Grace Joan. "Deorphanising G protein-coupled receptors : the search for fast steroid receptors." Thesis, University of Bristol, 2011. http://hdl.handle.net/1983/12fbf473-f360-4831-8123-42698aff4950.

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G protein coupled receptors (GPCRs) are the largest family of transmembrane receptors in the genome and are activated by a multitude of ligands including neuropeptides, hormones and sensory signals. The paraventricular nucleus (PVN) and supraoptic nucleus (SON) of the hypothalamus are important mediators in homeostatic control. Many modulators of PVN/SON activity, including neurotransmitters and hormones act via GPCRs - in fact over 100 non-chemosensory GPCRs have been detected in either the PVN or SON. The introduction to this thesis begins with a comprehensive summary of GPCR expression with
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Fischer, Katharina. "The mineralocorticoid receptor amino terminal transactivation domain investigation of structural plasticity and protein-protein interactions /." Thesis, Available from the University of Aberdeen Library & Historic Collections Digital Resources, 2008. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=24694.

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Thesis (Ph.D.)--Aberdeen University, 2008.<br>Title from web page (viewed on Feb. 23, 2009). With: Natural disordered sequences in the amino terminal domain of nuclear receptors : lessons from the androgen and glucocorticoid receptors / Iain J. McEwan ... et al. Nuclear Receptor Signalling. 2007: 5. Includes bibliographical references.
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Nawaz, Zafar. "Molecular Mechanism of Action of Steroid Hormone Receptors." Thesis, University of North Texas, 1992. https://digital.library.unt.edu/ark:/67531/metadc798398/.

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A novel bacterial expression system that is capable of producing high levels of soluble, stable, biologically active human vitamin D3 and estrogen receptors has been developed. The method utilizes ubiquitin fusion technology and a low temperature nalidixic acid induction of the lambda PL promoter. This system can produce large quantities of receptor antigen, but only a small fraction displays wild-type DNA and hormone binding properties. Therefore, the use of this system to overproduce receptors for crystallization studies is not practical. To overcome these problems, a 2 um based ubiquitin fu
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Smith, Robert A. "The Role of the Steroid Nuclear Receptor Genes in Breast Cancer." Thesis, Griffith University, 2006. http://hdl.handle.net/10072/365401.

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Breast cancer is a great source of morbidity and mortality in the developed world, being the most common cause of cancer death in Australian women and affecting roughly 1 in 10 women. The development and progression of cancers is a multi-stage process, involving numerous perturbations to normal cellular functions, especially to those genes which control cellular growth, cellular differentiation and DNA repair. Over time, these alterations combine to change normal cells into cancerous ones that typically no longer respond to normal control stimuli and grow with great rapidity. The nuclear recep
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Judd, Luke William. "Cholapods and cholaphanes : steroid based receptors for anion transport." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.544424.

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Cziko, Paul. "Molecular Physiological Evolution: Steroid Hormone Receptors and Antifreeze Proteins." Thesis, University of Oregon, 2015. http://hdl.handle.net/1794/18733.

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For my dissertation research I explored the diversity and functional evolution of steroid hormone receptors (SRs) in animals and the physiological implications of the evolution of antifreeze proteins in Antarctic notothenioid fishes. For the former, I discovered multiple new SRs from the vast and under-sampled swath of animal diversity known as invertebrates. I used the sequences of these and other newly discovered related receptors in combination with genomic data and molecular phylogenetic techniques to revise the understanding of the evolutionary history of this important gene family. Wh
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Shatnawi, Aymen Ahmad. "New Mechanisms of Transcriptional Regulation of the Folate Receptor and other genes by steroid Receptors." University of Toledo Health Science Campus / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=mco1201810595.

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Ayling, Alan J. "Steroidal electroneutral receptors for anions : synthesis and evaluation." Thesis, University of Bristol, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367663.

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Książki na temat "Steroid receptors"

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Castoria, Gabriella, and Ferdinando Auricchio, eds. Steroid Receptors. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1346-6.

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C, Spelsberg T., and Kumar Rajiv 1949-, eds. Steroid and sterol hormone action. Nijhoff, 1987.

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Pertschuk, Louis P. Immunocytochemistry for steroid receptors. CRC Press, 1990.

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1948-, Henderson David, ed. Steroid receptors and antihormones. New York Academy of Sciences, 1995.

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A, Lieberman Benjamin, ed. Steroid receptor methods: Protocols and assays. Humana Press, 2001.

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Castoria, Gabriella, and Ferdinando Auricchio. Steroid receptors: Methods and protocols. Humana Press, 2014.

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1925-, Pertschuk Louis P., and Lee Sin Hang 1932-, eds. Localization of putative steroid receptors. CRC Press, 1985.

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1950-, Watson Cheryl S., ed. The identities of membrane steroid receptors: ... and other proteins mediating nongenomic steroid action. Kluwer Academic Publishers, 2003.

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Meadow Brook Conference on Steroid Receptors in Health and Disease (1st 1987 Rochester, Mich.). Steroid receptors in health and disease. Plenum Press, 1988.

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Watson, Cheryl S., ed. The Identities of Membrane Steroid Receptors. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0339-2.

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Części książek na temat "Steroid receptors"

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Greiner, E. F., T. Wintermantel, and G. Schütz. "Steroid Receptors." In Transgenic Models in Pharmacology. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18934-0_19.

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Barber, Hugh R. K. "Sex Steroid Receptors." In Ovarian Carcinoma. Springer New York, 1993. http://dx.doi.org/10.1007/978-1-4613-9232-3_26.

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Jensen, E. V. "Steroid Hormone Receptors." In Current Topics in Pathology. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-75515-6_11.

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Müller, Judith M., and Roland Schüle. "Sex Steroid Receptors: Androgen Receptor, Estrogen Receptors, Progesterone Receptor." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57401-7_163.

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Müller, Judith M., and Roland Schüle. "Sex Steroid Receptors: Androgen Receptor, Estrogen Receptors, Progesterone Receptor." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-21573-6_163-1.

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Migliaccio, Antimo, Gabriella Castoria, and Ferdinando Auricchio. "Non-Genomic Action of Sex Steroid Hormones." In Nuclear Receptors. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-3303-1_15.

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Bergqvist, A. "Steroid receptors in endometriosis." In Modern Approaches to Endometriosis. Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3864-2_3.

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Gorski, Jack. "Steroid Receptors: A Historical Perspective." In Steroid Receptors in Health and Disease. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5541-0_2.

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Mendel, Dirk B., Jack E. Bodwell, Lynda I. Smith, and Allan Munck. "Structure and Function of Cytosolic Glucocorticoid Receptors in WEHI-7 Mouse Thymoma Cells: Receptor Composition and Phosphorylation." In Steroid and Sterol Hormone Action. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-2073-9_9.

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Schlanger, Simon, and Hannelore V. Heemers. "Functional Studies on Steroid Receptors." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7845-8_7.

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Streszczenia konferencji na temat "Steroid receptors"

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Ramezani, Sayed Reza, Afsaneh Mojra, and Mohammad Tafazzoli-Shadpour. "Investigating the migration of cells with different degrees of metastasis before and after treatment with chemical drugs targeting cytoskeleton structure, steroid and androgen receptor." In 2024 31st National and 9th International Iranian Conference on Biomedical Engineering (ICBME). IEEE, 2024. https://doi.org/10.1109/icbme64381.2024.10895809.

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Noriega, Yamilet, Miguel Rivas, and Elizabeth Langley. "Abstract C56: Characterization of PinX1 as a coregulator of steroid hormone receptors." In Abstracts: Second AACR International Conference on Frontiers in Basic Cancer Research--Sep 14-18, 2011; San Francisco, CA. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.fbcr11-c56.

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Massah, Shabnam, Na Li, Sarah Truong, Jane Foo, Gail Prins, and Ralph Buttyan. "Abstract 4397: Gli Activation by Steroid Receptors in Prostate and Breast Cancer Cells." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-4397.

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Massah, Shabnam, Na Li, Sarah Truong, Jane Foo, Gail Prins, and Ralph Buttyan. "Abstract 4397: Gli Activation by Steroid Receptors in Prostate and Breast Cancer Cells." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-4397.

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Herceg, Megan, and Amarda Shehu. "Structure- and Energy-based Analysis of Small Molecule Ligand Binding to Steroid Nuclear Receptors." In BCB '23: 14th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics. ACM, 2023. http://dx.doi.org/10.1145/3584371.3612949.

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Conzen, SD. "Abstract ES9-3: Androgen, progesterone and glucocorticoid receptors: Drivers of breast tumor progression or reprogramming of steroid receptors during breast tumor progression." In Abstracts: 2017 San Antonio Breast Cancer Symposium; December 5-9, 2017; San Antonio, Texas. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.sabcs17-es9-3.

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Bekić, Sofija S., Ivana Kuzminac, Srđan Bjedov, et al. "Use of Fluorescent Yeast-Based Biosensors for Evaluation of the Binding Affinities of New Steroid Hormone and Bile Acid Derivatives for Select Steroid Receptors." In IECB 2022. MDPI, 2022. http://dx.doi.org/10.3390/iecb2022-12282.

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Poulard, Coralie, and Michael Stallcup. "Abstract 3622: Crosstalk between automethylation and phosphorylation tightly regulates G9a and GLP coactivator function with steroid hormone receptors." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-3622.

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Guševac Stojanović, Ivana, Jelena Martinović, Zoran Stojanović, et al. "PROGESTERONE TREATMENT INCREASES PROGESTERONE RECEPTOR EXPRESSION IN MALE RATS WITH CEREBRAL HYPOPERFUSION." In 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry. Society of Physical Chemists of Serbia, 2024. https://doi.org/10.46793/phys.chem24i.243gs.

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Chronic cerebral hypoperfusion (CH), a reduced cerebral blood flow, is a significant factor in the development and progression of various neurodegenerative diseases for which adequate treatments are often lacking. To investigate the neuroprotective effects of the steroid hormone progesterone (P4) in a state of CH, we divided male Wistar rats into three groups: control group – rats treated with vehicle (flaxseed oil) and groups consisting of rats subjected to permanent bilateral common carotid artery occlusion (2VO) and treated with either flaxseed oil or P4 for seven days. We isolated the pref
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McNamara, KM, F. Guestini, T. Sauer, JC Lindstrøm, H. Sasano, and J. Geisler. "Abstract P3-05-08: Steroid receptors and steroidogenic enzymes in human breast cancer: Associations with breast cancer subtypes and clinical outcome." In Abstracts: 2016 San Antonio Breast Cancer Symposium; December 6-10, 2016; San Antonio, Texas. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.sabcs16-p3-05-08.

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Raporty organizacyjne na temat "Steroid receptors"

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Roth, Sharon Y. P/CAF Function in Transcriptional Activation by Steroid Hormone Receptors and Mammary Cell Proliferation. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada375129.

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Roth, Sharon Y. P/CAF Function in Transcriptional Activation by Steroid Hormone Receptors and Mammary Cell Proliferation. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada392348.

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Jeng, Meei-Huey. Roles of Steroid Receptor Coactivators in Breast Cancer. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada404705.

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Jeng, Meei-Hue Y. Roles of Steroid Receptor Coactivators in Breast Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada426309.

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Jeng, Meei-Huey. Roles of Steroid Receptor Coactivators in Breast Cancer. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada423247.

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McKenna, Neil J. The Role of Steroid Receptor Coactivator-1 in Breast Cancer. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada381169.

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Pietras, Richard J. Antiangiogenic Steroids and Growth Factor Receptors in Human Breast Cancer Therapy. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada431966.

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Riegel, Anna T. Ribozyme Targeting of Steroid Receptor Co-Activators: A Therapeutic Approach to Breast Cancer. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada403442.

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Cho, Jang H. The Role of Steroid Receptor Coactivators (SRCs) in the Development of Prostate Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada411955.

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Riegel, Anna T. Ribozyme Targeting of Steroid Receptor Co-Activators: A Therapeutic Approach to Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada412143.

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