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Artigos de revistas sobre o tema "RNA viruses"

Autor: Grafiati

Publicado: 4 de junho de 2021

Última modificação: 25 de julho de 2025

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1

Shi, Rui-Zhu, Yuan-Qing Pan, and Li Xing. "RNA Helicase A Regulates the Replication of RNA Viruses." Viruses 13, no. 3 (2021): 361. http://dx.doi.org/10.3390/v13030361.

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The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus replication. Herein, this review will provide an overview of the role of RHA in the replication of RNA viruses.

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2

Ahlquist, Paul. "Parallels among positive-strand RNA viruses, reverse-transcribing viruses and double-stranded RNA viruses." Nature Reviews Microbiology 4, no. 5 (2006): 371–82. http://dx.doi.org/10.1038/nrmicro1389.

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3

Yang, Jie, Hongjie Xia, Qi Qian, and Xi Zhou. "RNA chaperones encoded by RNA viruses." Virologica Sinica 30, no. 6 (2015): 401–9. http://dx.doi.org/10.1007/s12250-015-3676-2.

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4

Sokoloski, Kevin J., Carol J. Wilusz, and Jeffrey Wilusz. "Viruses: Overturning RNA Turnover." RNA Biology 3, no. 4 (2006): 140–44. http://dx.doi.org/10.4161/rna.3.4.4076.

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5

Enami, Masayoshi. "Negative-strand RNA viruses. Reverse genetics of negative-strand RNA viruses." Uirusu 45, no. 2 (1995): 145–57. http://dx.doi.org/10.2222/jsv.45.145.

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6

Ahlquist, P. "RNA-Dependent RNA Polymerases, Viruses, and RNA Silencing." Science 296, no. 5571 (2002): 1270–73. http://dx.doi.org/10.1126/science.1069132.

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7

Newburn, Laura R., and K. Andrew White. "Trans-Acting RNA–RNA Interactions in Segmented RNA Viruses." Viruses 11, no. 8 (2019): 751. http://dx.doi.org/10.3390/v11080751.

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RNA viruses represent a large and important group of pathogens that infect a broad range of hosts. Segmented RNA viruses are a subclass of this group that encode their genomes in two or more molecules and package all of their RNA segments in a single virus particle. These divided genomes come in different forms, including double-stranded RNA, coding-sense single-stranded RNA, and noncoding single-stranded RNA. Genera that possess these genome types include, respectively, Orbivirus (e.g., Bluetongue virus), Dianthovirus (e.g., Red clover necrotic mosaic virus) and Alphainfluenzavirus (e.g., Inf

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8

SATO, Hironori, and Masaru YOKOYAMA. "RNA viruses and mutations." Uirusu 55, no. 2 (2005): 221–29. http://dx.doi.org/10.2222/jsv.55.221.

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9

MINE, Akira, and Tetsuro OKUNO. "Viruses and RNA silencing." Uirusu 58, no. 1 (2008): 61–68. http://dx.doi.org/10.2222/jsv.58.61.

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10

Strauss, J. H., and E. G. Strauss. "Evolution of RNA Viruses." Annual Review of Microbiology 42, no. 1 (1988): 657–83. http://dx.doi.org/10.1146/annurev.mi.42.100188.003301.

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11

Carmichael, Gordon G. "Silencing viruses with RNA." Nature 418, no. 6896 (2002): 379–80. http://dx.doi.org/10.1038/418379a.

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12

King, Andrew M. Q. "RNA viruses do it." Trends in Genetics 3 (January 1987): 60–61. http://dx.doi.org/10.1016/0168-9525(87)90173-9.

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13

Billiau, A. "Double-stranded RNA viruses." Antiviral Research 5, no. 3 (1985): 191–92. http://dx.doi.org/10.1016/0166-3542(85)90052-x.

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14

Saiz, Juan-Carlos. "Vaccines against RNA Viruses." Vaccines 8, no. 3 (2020): 479. http://dx.doi.org/10.3390/vaccines8030479.

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15

Slamon, Dennis J., and Irvin S. Y. Chen. "RNA viruses and cancer." Infectious Diseases Newsletter 5, no. 4 (1986): 28–30. http://dx.doi.org/10.1016/0278-2316(86)90068-x.

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16

Lundstrom, Kenneth. "Self-Replicating RNA Viruses for RNA Therapeutics." Molecules 23, no. 12 (2018): 3310. http://dx.doi.org/10.3390/molecules23123310.

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Self-replicating single-stranded RNA viruses such as alphaviruses, flaviviruses, measles viruses, and rhabdoviruses provide efficient delivery and high-level expression of therapeutic genes due to their high capacity of RNA replication. This has contributed to novel approaches for therapeutic applications including vaccine development and gene therapy-based immunotherapy. Numerous studies in animal tumor models have demonstrated that self-replicating RNA viral vectors can generate antibody responses against infectious agents and tumor cells. Moreover, protection against challenges with pathoge

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17

Lundstrom, Kenneth. "Self-Amplifying RNA Viruses as RNA Vaccines." International Journal of Molecular Sciences 21, no. 14 (2020): 5130. http://dx.doi.org/10.3390/ijms21145130.

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Single-stranded RNA viruses such as alphaviruses, flaviviruses, measles viruses and rhabdoviruses are characterized by their capacity of highly efficient self-amplification of RNA in host cells, which make them attractive vehicles for vaccine development. Particularly, alphaviruses and flaviviruses can be administered as recombinant particles, layered DNA/RNA plasmid vectors carrying the RNA replicon and even RNA replicon molecules. Self-amplifying RNA viral vectors have been used for high level expression of viral and tumor antigens, which in immunization studies have elicited strong cellular

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18

Hammarskjöld, Marie-Louise. "RNA and lessons from viruses." RNA 21, no. 4 (2015): 632–33. http://dx.doi.org/10.1261/rna.050310.115.

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19

Raj, Pushker. "Classification of medically important viruses II: RNA viruses." Clinical Microbiology Newsletter 16, no. 17 (1994): 129–34. http://dx.doi.org/10.1016/0196-4399(94)90005-1.

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20

Fisher, Susie. "Are RNA Viruses Vestiges of an RNA World?" Journal for General Philosophy of Science 41, no. 1 (2010): 121–41. http://dx.doi.org/10.1007/s10838-010-9119-8.

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21

Chao, Shufen, Haoran Wang, Shu Zhang, et al. "Novel RNA Viruses Discovered in Weeds in Rice Fields." Viruses 14, no. 11 (2022): 2489. http://dx.doi.org/10.3390/v14112489.

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Weeds often grow alongside crop plants. In addition to competing with crops for nutrients, water and space, weeds host insect vectors or act as reservoirs for viral diversity. However, little is known about viruses infecting rice weeds. In this work, we used metatranscriptomic deep sequencing to identify RNA viruses from 29 weed samples representing 23 weed species. A total of 224 RNA viruses were identified: 39 newly identified viruses are sufficiently divergent to comprise new families and genera. The newly identified RNA viruses clustered within 18 viral families. Of the identified viruses,

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22

Weber, Friedemann, Valentina Wagner, Simon B. Rasmussen, Rune Hartmann, and Søren R. Paludan. "Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses." Journal of Virology 80, no. 10 (2006): 5059–64. http://dx.doi.org/10.1128/jvi.80.10.5059-5064.2006.

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ABSTRACT Double-stranded RNA (dsRNA) longer than 30 bp is a key activator of the innate immune response against viral infections. It is widely assumed that the generation of dsRNA during genome replication is a trait shared by all viruses. However, to our knowledge, no study exists in which the production of dsRNA by different viruses is systematically investigated. Here, we investigated the presence and localization of dsRNA in cells infected with a range of viruses, employing a dsRNA-specific antibody for immunofluorescence analysis. Our data revealed that, as predicted, significant amounts

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23

Geng, Guowei, Deya Wang, Zhifei Liu, et al. "Translation of Plant RNA Viruses." Viruses 13, no. 12 (2021): 2499. http://dx.doi.org/10.3390/v13122499.

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Plant RNA viruses encode essential viral proteins that depend on the host translation machinery for their expression. However, genomic RNAs of most plant RNA viruses lack the classical characteristics of eukaryotic cellular mRNAs, such as mono-cistron, 5′ cap structure, and 3′ polyadenylation. To adapt and utilize the eukaryotic translation machinery, plant RNA viruses have evolved a variety of translation strategies such as cap-independent translation, translation recoding on initiation and termination sites, and post-translation processes. This review focuses on advances in cap-independent t

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24

Silva-Júnior, Edeildo F. da. "Entry Inhibitors of RNA Viruses." Current Medicinal Chemistry 29, no. 4 (2022): 609–11. http://dx.doi.org/10.2174/092986732904220207113503.

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25

Pompei, Simone, Vittorio Loreto, and Francesca Tria. "Phylogenetic Properties of RNA Viruses." PLoS ONE 7, no. 9 (2012): e44849. http://dx.doi.org/10.1371/journal.pone.0044849.

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26

Simon-Loriere, Etienne, and Edward C. Holmes. "Why do RNA viruses recombine?" Nature Reviews Microbiology 9, no. 8 (2011): 617–26. http://dx.doi.org/10.1038/nrmicro2614.

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27

Steinhauer, D. A., and J. J. Holland. "Rapid Evolution of RNA Viruses." Annual Review of Microbiology 41, no. 1 (1987): 409–31. http://dx.doi.org/10.1146/annurev.mi.41.100187.002205.

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28

Gillespie, J. H. "Episodic evolution of RNA viruses." Proceedings of the National Academy of Sciences 90, no. 22 (1993): 10411–12. http://dx.doi.org/10.1073/pnas.90.22.10411.

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29

Zeller, Mark, and Kristian G. Andersen. "Backbone of RNA viruses uncovered." Nature 556, no. 7700 (2018): 182–83. http://dx.doi.org/10.1038/d41586-018-03923-w.

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30

Said, Elias A., Felipe Diaz-Griffero, Dorine Bonte, Daniel Lamarre, and Ali A. Al-Jabri. "Immune Responses to RNA Viruses." Journal of Immunology Research 2018 (June 12, 2018): 1–2. http://dx.doi.org/10.1155/2018/5473678.

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31

Russell, Stephen J. "RNA viruses as virotherapy agents." Cancer Gene Therapy 9, no. 12 (2002): 961–66. http://dx.doi.org/10.1038/sj.cgt.7700535.

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32

Woodland, David L. "A Focus on RNA Viruses." Viral Immunology 24, no. 2 (2011): 67–68. http://dx.doi.org/10.1089/vim.2011.ed.24.2.

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33

Rima, B. K. "Viruses in the RNA World." Biochemical Society Transactions 24, no. 1 (1996): 1–13. http://dx.doi.org/10.1042/bst0240001.

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34

BHUVANESHWARI, M., H. SUBRAMANYA, M. MURTHY, K. GOPINATH, and H. SAVITHRI. "Architecture of small RNA viruses." Progress in Crystal Growth and Characterization of Materials 34, no. 1-4 (1997): 1–10. http://dx.doi.org/10.1016/s0960-8974(97)00001-6.

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35

Michalakis, Y. "EVOLUTION: Epistasis in RNA Viruses." Science 306, no. 5701 (2004): 1492–93. http://dx.doi.org/10.1126/science.1106677.

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36

Colbère-Garapin, Florence, Bruno Blondel, Aure Saulnier, Isabelle Pelletier, and Karine Labadie. "Silencing viruses by RNA interference." Microbes and Infection 7, no. 4 (2005): 767–75. http://dx.doi.org/10.1016/j.micinf.2005.02.003.

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37

Ruigrok, R. W. H. "Assembly of enveloped RNA viruses." FEBS Letters 202, no. 1 (1986): 159. http://dx.doi.org/10.1016/0014-5793(86)80670-6.

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38

Lang, Andrew S., Matthew L. Rise, Alexander I. Culley, and Grieg F. Steward. "RNA viruses in the sea." FEMS Microbiology Reviews 33, no. 2 (2009): 295–323. http://dx.doi.org/10.1111/j.1574-6976.2008.00132.x.

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39

Drake, J. W., and J. J. Holland. "Mutation rates among RNA viruses." Proceedings of the National Academy of Sciences 96, no. 24 (1999): 13910–13. http://dx.doi.org/10.1073/pnas.96.24.13910.

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40

Dadley-Moore, Davina. "RNA viruses: all bases covered?" Nature Reviews Immunology 6, no. 5 (2006): 341. http://dx.doi.org/10.1038/nri1856.

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41

Rossmann, Michael G. "The evolution of RNA viruses." BioEssays 7, no. 3 (1987): 99–103. http://dx.doi.org/10.1002/bies.950070302.

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42

Swaminathan, Gokul, Julio Martin-Garcia, and Sonia Navas-Martin. "RNA viruses and microRNAs: challenging discoveries for the 21st century." Physiological Genomics 45, no. 22 (2013): 1035–48. http://dx.doi.org/10.1152/physiolgenomics.00112.2013.

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RNA viruses represent the predominant cause of many clinically relevant viral diseases in humans. Among several evolutionary advantages acquired by RNA viruses, the ability to usurp host cellular machinery and evade antiviral immune responses is imperative. During the past decade, RNA interference mechanisms, especially microRNA (miRNA)-mediated regulation of cellular protein expression, have revolutionized our understanding of host-viral interactions. Although it is well established that several DNA viruses express miRNAs that play crucial roles in their pathogenesis, expression of miRNAs by

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43

Yang, Siwy Ling, Riccardo Delli Ponti, Yue Wan, and Roland G. Huber. "Computational and Experimental Approaches to Study the RNA Secondary Structures of RNA Viruses." Viruses 14, no. 8 (2022): 1795. http://dx.doi.org/10.3390/v14081795.

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Most pandemics of recent decades can be traced to RNA viruses, including HIV, SARS, influenza, dengue, Zika, and SARS-CoV-2. These RNA viruses impose considerable social and economic burdens on our society, resulting in a high number of deaths and high treatment costs. As these RNA viruses utilize an RNA genome, which is important for different stages of the viral life cycle, including replication, translation, and packaging, studying how the genome folds is important to understand virus function. In this review, we summarize recent advances in computational and high-throughput RNA structure-m

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44

Richaud, Aurélien, Lise Frézal, Stephen Tahan, et al. "Vertical transmission in Caenorhabditis nematodes of RNA molecules encoding a viral RNA-dependent RNA polymerase." Proceedings of the National Academy of Sciences 116, no. 49 (2019): 24738–47. http://dx.doi.org/10.1073/pnas.1903903116.

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Here, we report on the discovery in Caenorhabditis nematodes of multiple vertically transmitted RNAs coding for putative RNA-dependent RNA polymerases. Their sequences share similarity to distinct RNA viruses, including bunyaviruses, narnaviruses, and sobemoviruses. The sequences are present exclusively as RNA and are not found in DNA form. The RNAs persist in progeny after bleach treatment of adult animals, indicating vertical transmission of the RNAs. We tested one of the infected strains for transmission to an uninfected strain and found that mating of infected animals with uninfected anima

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45

Boonrod, Kajohn, and Gabriele Krczal. "Inhibitions of Positive-Sense (ss) RNA Viruses RNA-Dependent RNA Polymerases." Current Enzyme Inhibition 5, no. 4 (2009): 234–44. http://dx.doi.org/10.2174/157340809789630262.

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46

Nicholson, Beth L., and K. Andrew White. "Functional long-range RNA–RNA interactions in positive-strand RNA viruses." Nature Reviews Microbiology 12, no. 7 (2014): 493–504. http://dx.doi.org/10.1038/nrmicro3288.

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47

Wang, Wenqing, Xianhong Wang, Chunyan Tu, et al. "Novel Mycoviruses Discovered from a Metatranscriptomics Survey of the Phytopathogenic Alternaria Fungus." Viruses 14, no. 11 (2022): 2552. http://dx.doi.org/10.3390/v14112552.

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Alternaria fungus can cause notable diseases in cereals, ornamental plants, vegetables, and fruits around the world. To date, an increasing number of mycoviruses have been accurately and successfully identified in this fungus. In this study, we discovered mycoviruses from 78 strains in 6 species of the genus Alternaria, which were collected from 10 pear production areas using high-throughput sequencing technology. Using the total RNA-seq, we detected the RNA-dependent RNA polymerase of 19 potential viruses and the coat protein of two potential viruses. We successfully confirmed these viruses u

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48

Bwalya, John, and Kook-Hyung Kim. "The Crucial Role of Chloroplast-Related Proteins in Viral Genome Replication and Host Defense against Positive-Sense Single-Stranded RNA Viruses." Plant Pathology Journal 39, no. 1 (2023): 28–38. http://dx.doi.org/10.5423/ppj.rw.10.2022.0139.

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Plant viruses are responsible for worldwide production losses of numerous economically important crops. The most common plant RNA viruses are positivesense single-stranded RNA viruses [(+)ss RNA viruses]. These viruses have small genomes that encode a limited number of proteins. The viruses depend on their host’s machinery for the replication of their RNA genome, assembly, movement, and attraction to the vectors for dispersal. Recently researchers have reported that chloroplast proteins are crucial for replicating (+)ss plant RNA viruses. Some chloroplast proteins, including translation initia

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49

Ott Rutar, Sabina, and Dusan Kordis. "Analysis of the RNA virome of basal hexapods." PeerJ 8 (January 9, 2020): e8336. http://dx.doi.org/10.7717/peerj.8336.

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The diversity and evolution of RNA viruses has been well studied in arthropods and especially in insects. However, the diversity of RNA viruses in the basal hexapods has not been analysed yet. To better understand their diversity, evolutionary histories and genome organizations, we searched for RNA viruses in transcriptome and genome databases of basal hexapods. We discovered 40 novel RNA viruses, some of which are also present as endogenous viral elements derived from RNA viruses. Here, we demonstrated that basal hexapods host 14 RNA viral clades that have been recently identified in inverteb

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50

Kolakofsky, Daniel. "A short biased history of RNA viruses." RNA 21, no. 4 (2015): 667–69. http://dx.doi.org/10.1261/rna.049916.115.

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