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Статті в журналах з теми "1QRM"

Автор: Grafiati

Опубліковано: 25 липня 2024

Оновлено: 31 липня 2025

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1

Johnson, Michael B. "Wrapping Up 1QM." Dead Sea Discoveries 30, no. 3 (2023): 262–91. http://dx.doi.org/10.1163/15685179-bja10047.

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Abstract This article evaluates the debated placements of fragments in the reconstruction of the War Scroll from Cave 1 (1QM). There are three fragments (frags. 3, 9, 10) and one large fragment cluster (1QM 2, 8, DSSHU pl. 34; 1Q33 2) that are contested in 1QM scholarship. These placements are important for establishing the text of 1QM and the determination of whether there was another War Scroll from Cave 1 among the fragments assigned to 1QM and 1Q33. I will evaluate the remaining debates about fragment placements in 1QM, focusing especially on Hanan and Esther Eshel’s proposal (2000) that t

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2

Screnock, John. "Verbal Argument Structure in the War Scroll." Dead Sea Discoveries 27, no. 3 (2020): 392–409. http://dx.doi.org/10.1163/15685179-bja10013.

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Abstract This essay presents the results of an extended study of verbal argument structure in the War Scroll (1QM). I first establish a method based in generative linguistic theory. I then illustrate this method with a discussion of the argument structure of Qal ‮יצא‬‎ in 1QM and other Dead Sea Scrolls. Following this case study, I present the data from 1QM on verb argument structure—specifically, instances where 1QM adds evidence that is not covered in previous studies of the Dead Sea Scrolls. 1QM presents few developments from earlier Hebrew; I argue that such continuity is significant. I co

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3

Screnock, John. "Word Order in the War Scroll (1QM) and Its Implications for Interpretation." Dead Sea Discoveries 18, no. 1 (2011): 29–44. http://dx.doi.org/10.1163/156851711x551563.

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AbstractIn studies of Qumran Hebrew, syntax has been somewhat neglected. The present study attempts to help fill in our understanding of QH syntax, and word order specifically. The data of 1QM can best be explained using a Subject-Verb model. However, the model is not perfect. Consideration of the strange word order patterns of and leads to a revision of the SV model, which is better able to account for all the word order phenomena in 1QM. The basic word order of 1QM is best described as Subject-Verb, with inversion triggered by the fronting of a non-subject element or by the use of an intrans

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4

Walsh, Matthew L. "What Angel or Prince Is Like Your Redemptive Help?" Dead Sea Discoveries 32, no. 2 (2025): 231–61. https://doi.org/10.1163/15685179-bja10065.

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Abstract The rhetorical flourish of 1QM 13:14 has been interpreted as a reminder that the ultimate resource of the sectarian community is not an angel but the God of Israel. This reading, however, stands in tension with the many sections of the War Scroll that look expectantly to the eschaton for the martial “help” of the angels. This study will develop a lesser-known understanding of 1QM 13:14: that no angel can compare to the “help” appointed by God, namely, the Prince of Light/Michael. Proposed reconstructions of the lacuna of 1QM 13:14 and the relevance of a War Scroll-related fragment (4Q

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5

Haigh, Rebekah. "Oral Aspects: A Performative Approach to 1QM." Dead Sea Discoveries 26, no. 2 (2019): 189–219. http://dx.doi.org/10.1163/15685179-12341502.

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AbstractAs the product of a textual community imbedded in an oral culture, the War Scroll can be rewardingly approached as a composition intended for a community of hearers. Indeed, this article demonstrates that 1QM retained an orally fluid textuality and preserves a variety of textual indicators of performativity: hints of oral engagement, accumulation of imitable practices, and reliance on rhetorical techniques suited to the ear. In examining the performative potentials in the War Scroll’s prescriptive (cols. 1–9), prayer (cols. 10–14), and dramatic (cols. 15–19) material, I argue that 1QM

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6

Kowalski, Marcin. "Holy War in Corinth: The Apocalyptic Background of Paul’s Struggle against Opponents in 2 Cor 10:3–6." Religions 14, no. 5 (2023): 630. http://dx.doi.org/10.3390/rel14050630.

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The purpose of this article is to explore what kind of light apocalyptic eschatology can shed on our understanding of Paul’s argumentation in 2 Cor 10–13. The focus is on 2 Cor 10:3–6, where Paul, using the topos of holy war, describes his struggle against the opponents in Corinth. The apostle elaborates on a biblical theme, which also appears in Jewish apocalyptic texts, such as 1QM and T. 12. Patr. Comparing 2 Corinthians with this literature allows us to see certain similarities: the performative nature of 2 Cor and 1QM; the radical division into the servants of light and the servants of da

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7

Campbell, Jonathan G. "The War Texts: 1QM and Related Manuscripts." Journal of Jewish Studies 56, no. 2 (2005): 343–45. http://dx.doi.org/10.18647/2625/jjs-2005.

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8

Parry, Manzoor Ahmad, Rayees Yousuf Sheikh, Raja Kaamil Qadri, Muzafar Maqsood Wani, Imtiyaz Wani, and Mohammad Ashraf Bhat. "Clinical Characteristics and Outcome of Kidney Transplant Recipients Infected with COVID-19: A Retrospective Observational Study." Indian Journal of Transplantation 18, no. 4 (2024): 379–84. https://doi.org/10.4103/ijot.ijot_6_24.

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Background: This study investigated the clinical characteristics and outcomes of kidney transplant recipients (KTRs) who contracted COVID-19. Methods: In this retrospective study, we analyzed data from 122 KTRs confirmed to have COVID-19. Results: The mean age in patients with mild COVID-19 disease was 37.1 ± 9.1 years, whereas those with moderate and severe disease were 44.7 ± 13.7 and 48.1 ± 11.2 years, respectively (P = 0.02). The median neutrophil-to-lymphocyte ratio was 4.2 (interquartile range [IQR] 3.0–6.8) for mild cases, 6.5 (IQR: 5.0–10.8) for moderate cases, and 19 (IQR: 7.0–24.7) f

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9

Siegismund, Kasper. "Once Again on Word Order in the War Scroll (1QM)." Dead Sea Discoveries 25, no. 1 (2018): 83–106. http://dx.doi.org/10.1163/15685179-12341452.

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Abstract This contribution offers a critical evaluation of John Screnock’s hypothesis that the basic word order in 1QM is subject-verb, with inversion triggered by fronting of non-subject elements or by the use of intransitive verbs. After a detailed examination of the evidence, the opposite conclusion is reached. Basic word order is verb-subject, with inversion to subject-verb order with pragmatically marked subjects (focus fronting). There seems to be no causal relationship between transitivity and word order. Furthermore, it is argued that Screnock’s interpretation of 1QM 1:1–3 (which flows

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10

BOGNER, William C., and Thomas HOWARD. "Sustaining International Linkages: A Dynamic Competence View." Management international 1, no. 1 (1996): 1–14. http://dx.doi.org/10.59876/a-jk87-1qmr.

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Strategic alliances have been growing in popularity among firms over the past 10 years. The basis for the formation of truly strategic alliance has been presented by several authors who use the theoretical foundations that are popular in strategic management, in particular the resource-based theory of the firm, organizational learning theory and industrial organizational economics. Still, little has been said about why these alliances are sustained. This paper takes those same theoretical bases and constructs a basic set of propositions about the continuation of strategic alliances.

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11

Vanonen, Hanna. "Conquering the World: The War Scroll (1QM) Reconsidered." Journal of Jewish Studies 62, no. 1 (2011): 190–91. http://dx.doi.org/10.18647/3032/jjs-2011.

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12

Duhaime, Jean. "Conquering the World: The War Scroll (1QM) Reconsidered." Journal for the Study of Judaism 41, no. 3 (2010): 431–32. http://dx.doi.org/10.1163/157006310x503973.

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13

Wenthe, Dean O. "The Use of the Hebrew Scriptures in 1Qm." Dead Sea Discoveries 5, no. 3 (1998): 290–319. http://dx.doi.org/10.1163/156851798x00145.

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14

Twomey, Rosie, T. Wayne Matthews, Steven C. Nakoneshny, et al. "From Pathways to Practice: Impact of Implementing Mobilization Recommendations in Head and Neck Cancer Surgery with Free Flap Reconstruction." Cancers 13, no. 12 (2021): 2890. http://dx.doi.org/10.3390/cancers13122890.

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One of the foundational elements of enhanced recovery after surgery (ERAS) guidelines is early postoperative mobilization. For patients undergoing head and neck cancer (HNC) surgery with free flap reconstruction, the ERAS guideline recommends patients be mobilized within 24 h postoperatively. The objective of this study was to evaluate compliance with the ERAS recommendation for early postoperative mobilization in 445 consecutive patients who underwent HNC surgery in the Calgary Head and Neck Enhanced Recovery Program. This retrospective analysis found that recommendation compliance increased

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15

Wortley, John. "Geriatric Pathology à L'ancienne." International Journal of Aging and Human Development 53, no. 3 (2001): 167–79. http://dx.doi.org/10.2190/8q6m-agje-y5ll-1qem.

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16

Gabany, Steve G., and Portia Plummer. "The Marihuana Perception Inventory: The Effects of Substance Abuse Instruction." Journal of Drug Education 20, no. 3 (1990): 235–45. http://dx.doi.org/10.2190/0bwq-vv6t-1qcm-vb8h.

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17

Krieger, Nancy. "Solidarity and AIDS: Introduction." International Journal of Health Services 21, no. 3 (1991): 505–10. http://dx.doi.org/10.2190/1q0m-1jjt-3mhu-5clj.

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18

Finsterbusch, Karin, та Norbert Jacoby. "אשר-Zitateinleitungssätze in Jeremia und 1QM. Anmerkungen zu 1QM 10:6, zu der hebräischen Vorlage von lxx-Jer 26:13; 49:19 sowie zu mt-Jer 14:1; 46:1; 47:1; 49:34". Vetus Testamentum 65, № 4 (2015): 558–66. http://dx.doi.org/10.1163/15685330-12301245.

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In mt-Jer there are four cases of a peculiar אשר clause, which seems to be syntactically isolated (mt-Jer 14:1; 46:2; 47:1 und 49:34). However, the existence of three similar cases has been hitherto overlooked (two in the supposed Hebrew Vorlage of the lxx-Jer and one in 1QM). In this paper, we shall argue that the function of this אשר clause is to introduce a quotation. In syntactical terms, the relative clause is the predicate and the quotation the subject of a nominal clause.

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19

Mulyati, Budi. "Simulasi Penambatan Isoflavon pada Reseptor Estrogen β sebagai Pengobatan Kanker Payudara Secara In Silico". Jurnal Informatika, Teknologi dan Sains 1, № 1 (2022): 26–34. http://dx.doi.org/10.56244/formateks.v1i1.485.

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Reseptor estrogen-β (ER- β) merupakan faktor penting dalam penghambatan daninvasi terhadap sel kanker payudara. Reseptor estrogen-β yang terkompleks dengan genisteinseringkali dijadikan model target terhadap aksi obat. Kedelai mengandung isoflavon, salahsatu bahan pangan yang terbuat dari kedelai adalah tempe. Pada tempe terdapat empat jenisisoflavon yaitu daidzein, glisitein, genistein dan faktor II (6,7,4- trihidroksi isoflavon). Tujuandari penelitian ini adalah menentukan urutan ligan yang berinteraksi lebih kuat terhadap RE αserta menentukan gugus fungsi yang berperan aktif dan jenis inter

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20

Nurlelasari, Nurlelasari, Desi Harneti, Rani Maharani, et al. "Morelloflavone and Molecular Docking from Stembark of Chisocheton lasiocarpus and Its Cytotoxic Activity Against Breast Cancer Mcf-7 Cell Lines." Molekul 18, no. 2 (2023): 200. http://dx.doi.org/10.20884/1.jm.2023.18.2.6845.

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Chisocheton is a plant of the Meliaceae family which has been known as a source of limonoids, triterpenoids, steroids, alkaloids and phenolics. This plant is the second largest in the Meliaceae, with 53 species widely distributed in tropical and subtropical regions including Indonesia. From this genus, compounds that have interesting activities have been found, including anti-inflammatory, antimalarial, cytotoxic, antitumor and anticancer. One of the species that has the potential to find new compounds is Chisocheton lasiocarpus because there are still few phytochemical studies. This study aim

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21

Screnock, John. "The Syntax of Cardinal Numerals in Judges, Amos, Esther and 1QM*." Journal of Semitic Studies 63, no. 1 (2018): 125–54. http://dx.doi.org/10.1093/jss/fgx039.

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22

Domka, Natalia. "Archanioł Gabriel w piśmiennictwie qumrańskim." Biblical Annals 14, no. 1 (2024): 77–91. http://dx.doi.org/10.31743/biban.14937.

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Artykuł stanowi próbę przedstawienia postaci anioła Gabriela w kontekście siedmiu manuskryptów qumrańskich, w których ona występuje, czyli w trzech tekstach hebrajskich (1QM, 4Q285, 1Q19) oraz w czterech tekstach aramejskich (4Q201, 4Q202, 4Q529, 4Q557). Podjęte analizy stanowią przegląd tekstów z elementami egzegezy, tj. charakterystykę historyczno-literacką oraz zestawienie tekstu źródłowego i polskiego przekładu wymienionych manuskryptów. Z jednej strony można zauważyć różne sposoby przedstawienia archanioła – pełni różne role, występuje w relacji do innych postaci nadprzyrodzonych lub jako

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23

Piamenta, Moshe. "Trumpets and Shofarot in the War Scroll (1QM): Musical and Terminological Insights." Hebrew Union College Annual 92 (December 1, 2021): 15–45. http://dx.doi.org/10.15650/hebruniocollannu.92.2.

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This article is an archaeo-musicological study of the trumpets (ḥaṣoṣrot, metal wind instruments) and shofarot (animal horns) in the War Scroll from the Dead Sea Scrolls of Qumran. The study of ancient Jewish music is largely uncharted territory. Many musical terms that appear in the Bible, Second Temple writings, and rabbinic literature, including the names of musical instruments, are not fully understood and there are many questions about their interpretation. For this reason, the War Scroll is one of the most important sources for archaeo-musicological scholarship of the ancient world gener

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24

van Appeldoorn, Gijsbert. "An Eschatological Framework and Social Identity in 1QM 1:1–15 and 1 Thessalonians 5:1–11." Religions 16, no. 2 (2025): 196. https://doi.org/10.3390/rel16020196.

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In the Qumran War Scroll (1QM) 1:1–15 and 1 Thessalonians 5:1–11, almost the same eschatological interpretative framework is created with words from the semantic domains of light and darkness, kinship, war, ethics, divinity and time. Although the constructed frameworks in these texts look alike, their impact on the self-understanding of the respective Qumran and Thessalonian communities is different. This article aims to reconstruct these frameworks from the texts by using semantic dictionaries and to reconstruct the probable impact of these frameworks on the self-understanding of the communit

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25

Allegue, Jaime Vázquez. "Le ideologie del Rotolo della Guerra (1QM): Studio sulla genesi e la datazione dell'opera." Journal for the Study of Judaism 40, no. 1 (2009): 113–14. http://dx.doi.org/10.1163/157006308x375870.

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26

Gianti, Lisna. "PENAMBATAN MOLEKUL SENYAWA METABOLIT SEKUNDER BAWANG DAYAK (Eleutherine bulbosa) SEBAGAI ANTIKANKER PAYUDARA." Jurnal Sabdariffarma 12, no. 2 (2025): 33–40. https://doi.org/10.53675/jsfar.v12i2.1428.

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Latar belakang: Penemuan senyawa baru dari sumber alami untuk pengobatan] kanker payudara sangat penting bagi pengembangan makanan fungsional dan industri farmasi. Sumber daya alam dengan aktivitas potensial melawan kanker payudara adalah bawang dayak, Eleutherine bulbosa tetapi identitas konstituen aktifnya dan mekanisme kerjanya masih belum dieksplorasi. Oleh karena itu, penelitian ini berfokus pada farmakoinformatika aktivitas dan profil metabolite.Tujuan: penelitian ini adalah untuk menentukan senyawa yang paling berpotensi sebagai anti kanker payudara pada tanaman bawang dayak (Eleutherin

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27

Siebesma-Mannens, Femke. "Double Object Constructions in DSS Hebrew." Dead Sea Discoveries 27, no. 3 (2020): 372–91. http://dx.doi.org/10.1163/15685179-bja10017.

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Abstract In this article an overview is given of the verbal valence patterns of the verb ‮נתן‬‎ in the Dead Sea Scrolls. Four patterns are distinguished for this verb: 1. ‮נתן‬‎ + OBJECT to produce; 2. + ‮נתן‬‎ OBJECT + RECIPIENT to give to; 3. ‮נתן‬‎ + OBJECT + LOCATION to place; 4. ‮נתן‬‎ + OBJECT + 2ND OBJECT to make into. All occurrences of the verb in the DSS corpus used, consisting of 1QHa, 1QS, 1QM, and 1QpHab, are discussed and divided into one of these patterns. This study shows that pattern 3 occurs most, followed by pattern 2, and that it can be argued that pattern 1 and 4 also occu

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28

Frisch, Alexandria, and Lawrence H. Schiffman. "The Body in Qumran Literature: Flesh and Spirit, Purity and Impurity in the Dead Sea Scrolls." Dead Sea Discoveries 23, no. 2 (2016): 155–82. http://dx.doi.org/10.1163/15685179-12341386.

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This article examines the concept of the body within a wide range of Qumran literature. In a comparison with the biblical tradition, which does not evince a consistent and systematic idea of the body, this article demonstrates that the sectarians developed their own somatic model. The sectarian model, as revealed through a close reading of such texts as Hodayot, 1QS, 1QSa, CD and 1QM, is one that repeatedly emphasized the body as a corporate entity comprised jointly of flesh and spirit. This article then reexamines the same Qumran texts to show that this concept of the body explains the extrem

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29

Alsalamah, Sulaiman A., Mohammed Ibrahim Alghonaim, Abdu Ali Y. Moafa, and Mukul Sharma. "Exploring the effect and molecular docking interaction of carboxypeptidase and amidohydrolase on ochratoxin A and zearalenone degradation." BioResources 20, no. 3 (2025): 5575–86. https://doi.org/10.15376/biores.20.3.5575-5586.

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To keep consumers from the hazard of exposure to mycotoxins and meet the allowed limits, numerous physical and chemical approaches for eliminating Ochratoxin A (OTA) and Zearalenone (ZEN) have been studied. Enzymes technology, including carboxypeptidase and amidohydrolase, were evaluated on their ability to degrade OTA and ZEN. Two fungi, namely Aspergillus ochraceus and Fusarium graminearum, were isolated with their mycotoxins OTA and ZEN from contaminated yellow corn grains. Carboxypeptidase at 0.50 and 0.75 U/mL caused 33.3 and 57.7% degradation of OTA, and 27.1 and 57.2% degradation of ZEN

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30

Regev, Eyal. "Trumpets and Epitaphs." Dead Sea Discoveries 32, no. 2 (2025): 203–30. https://doi.org/10.1163/15685179-bja10064.

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Abstract Cols. 3–9 of 1QM appear to address military organization and tactics. However, the predominant focus in these sections extends beyond warfare to ceremonial elements such as trumpets, banners and the ritual inscriptions on them. Even the weaponry is described with meticulous attention to aesthetic and nonfunctional details, as one might find in a museum exhibition. A literary-rhetorical analysis of these columns points to ritual aspects crafted to evoke in the reader a perception of the war as a sacred, ritualistic event. This is achieved through repeated motifs, categorization into li

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31

Habib, Haroon, Md Rafi Haider, Shikha Sharma та ін. "Molecular interactions of vinclozolin metabolites with human estrogen receptors 1GWR-α and 1QKM and androgen receptor 2AM9-β: Implication for endocrine disruption". Toxicology Mechanisms and Methods 30, № 5 (2020): 370–77. http://dx.doi.org/10.1080/15376516.2020.1747123.

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32

Abegg, Martin G. "Conquering the World: The War Scroll (1QM) Reconsidered. Studies on the Texts of the Desert of Judah 76." Bulletin for Biblical Research 22, no. 4 (2012): 588–90. http://dx.doi.org/10.2307/26424353.

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33

Dimant, Devorah. "Signification et importance des manuscrits de la mer Morte. L'état actuel des études qoumrâniennes." Annales. Histoire, Sciences Sociales 51, no. 5 (1996): 975–1003. http://dx.doi.org/10.3406/ahess.1996.410901.

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Les manuscrits de la mer Morte, depuis leur découverte il y a une cinquantaine d'années dans onze grottes situées non loin de Jéricho, ont occupé une place unique tant dans la recherche scientifique qu'auprès du grand public. Pour la première fois, on découvrait en Palestine d'anciens manuscrits hébreux et araméens à caractère littéraire. Le fait qu'on ait pu les dater des environs de la naissance du christianisme a largement contribué à susciter la curiosité générale, et on se mit à espérer que cette découverte permettrait d'en éclairer les origines. La chance fut véritablement au rendez-vous

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34

Stauber, Chad Martin. "Conquering the World: The War Scroll (1QM) Reconsidered. By Brian Schultz. STDJ 76. Leiden: Brill, 2009. Hardcover. Pp. viii + 456. € 162.00/US$ 231.00. ISBN 978-90-04-16820-6." Dead Sea Discoveries 19, no. 2 (2012): 239–40. http://dx.doi.org/10.1163/156851712x644749.

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35

Ulanja, Mark Bilinyi, Bryce D. Beutler, Samuel B. Governor, et al. "The impact of COVID-19 on mortality, length of stay, and cost of care among patients with gastrointestinal malignancies: A propensity score-matched analysis." Journal of Clinical Oncology 41, no. 16_suppl (2023): e15510-e15510. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e15510.

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e15510 Background: The SARS-CoV-2 (COVID-19) pandemic has had a lasting impact on the care of cancer patients. Multiple studies have shown that individuals with cancer are at high risk of serious complications in the setting of COVID-19 infection, but the impact in patients with gastrointestinal (GI) malignancies remain incompletely understood. We aimed to assess the impact of COVID-19 infection on mortality, length of stay (LOS), and cost of care among patients with GI malignancies, and identify differences in outcomes based on primary tumor site. Methods: We analyzed discharge encounters col

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Garrett, Gill. "Golden Opportunities - Better Communication with Old PeopleGolden Opportunities - Better Communication with Old People Elspeth Stirling Peter Brent Marketing 135 Sandy ford Road, Newcastle upon Tyne NE2 1QR 1989 £75 + VA T purchase or £10 + VAT hire." Elderly Care 1, no. 3 (1989): 29. http://dx.doi.org/10.7748/eldc.1.3.29.s23.

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Yin, Bing, and Lan Luo. "The anisotropy of internal magnetic field on central ion is capable of imposing great impact on the quantum tunneling of magnetization of Kramers single-ion magnet." Physical Chemistry Chemical Physics, 2021. http://dx.doi.org/10.1039/d0cp05470d.

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In this work, a theoretical method, taking into account the anisotropy of internal magnetic field (~Bint), is proposed to predict the rate of quantum tunneling of magnetization (QTM), i.e., τ-1QTM,...

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Condren, Janson. "The End of Desire: On the Meaning of תשׁוקה in the Hebrew Scriptures and the Dead Sea Scrolls". Journal of Hebrew Scriptures 24 (19 лютого 2025). https://doi.org/10.5508/jhs29657.

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Despite the long-standing tradition of translating תשׁוקה as “desire” in its three biblical occurrences (Gen 3:16; 4:7; Cant 7:11 [Eng. 10]), recent studies have put forth alternatives such as “turning, return,” “preoccupation, devotion” and “driving.” This essay examines these possibilities in light of the usage of תשׁוקה in the Dead Sea Scrolls (1QM 13:12; 15:10; 17:4; 1QS 11:22; 4QInstrb 2:4). The meaning “desire” is shown to be particularly problematic, not only as a result of its absence in the earliest biblical versions, but also due to the expression לעפר תשׁוקתו immediately after a dep

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Johnson, Michael B. "Getting a Handle on 1QIsaiahb." Dead Sea Discoveries, July 20, 2021, 1–26. http://dx.doi.org/10.1163/15685179-bja10019.

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Abstract This article examines Hartmut Stegemann’s preliminary proposal that the remains of the beginning handle sheet of 1QHa have survived and provide useful data for reconstructing the scroll. According to Stegemann, this handle sheet supplies critical material evidence that three columns existed before 1QHa 4, the first substantially extant column in the manuscript. The handle sheet was recovered from one of three scrolls, 1QM, 1QIsab, and 1QHa. Each of these possibilities is considered, and a new proposal that the handle sheet belongs to the end of 1QIsab is advanced. The article offers a

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Kumbar, Bhimanagoud, Shivananda Kandagalla, Bharath B R, Sharath B S, and Riaz Mahmood. "Protein-protein interaction and molecular dynamics of Iturin A gene on effector proteins Phytophthora infestans." Combinatorial Chemistry & High Throughput Screening 23 (July 20, 2020). http://dx.doi.org/10.2174/1386207323666200720012054.

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Aim And Objectives: Phytophthora infestans (Mont.) de Bary, fungal pathogen it causes late blight, which results in devastating economic loss among the Solanaceae. The bacillus lipopeptides shows the antagonistic activity against the many plant pathogens, among bacillus lipopeptides Iturin A reported as the antifungal gene. Hence, to understand the in silico antifungal activity, we have selected gene iturin A (AXN89987) produced by Bacillus spp to check the molecular dynamics study with the effector proteins of the P. infestanse. In this concern known effectors proteins of P. infestans were su

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Islam, Sirajul, Md Al Amin, Kannan R. R. Rengasamy, A. K. M. Mohiuddin, and Shahin Mahmud. "Structure‐based pharmacophore modeling for precision inhibition of mutant ESR2 in breast cancer: A systematic computational approach." Cancer Medicine 13, no. 15 (2024). http://dx.doi.org/10.1002/cam4.70074.

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AbstractBackgroundBreast cancer, a leading cause of female mortality, is closely linked to mutations in estrogen receptor beta (ESR2), particularly in the ligand‐binding domain, which contributed to altered signaling pathways and uncontrolled cell growth.Objectives/AimsThis study investigates the molecular and structural aspects of ESR2 mutant proteins to identify shared pharmacophoric regions of ESR2 mutant proteins and potential therapeutic targets aligned within the pharmacophore model.MethodsThis study was initiated by establishing a common pharmacophore model among three mutant ESR2 prote

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Li, Miao-Nan, Shao-Huan Qian, Zhuo-Ya Yao, et al. "Correlation of serum N-Acetylneuraminic acid with the risk and prognosis of acute coronary syndrome: a prospective cohort study." BMC Cardiovascular Disorders 20, no. 1 (2020). http://dx.doi.org/10.1186/s12872-020-01690-z.

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Abstract Background N-acetylneuraminic acid (Neu5Ac) is a functional metabolite involved in coronary artery disease (CAD). We aimed to evaluate the relationship between serum Neu5Ac and the risk and prognosis of acute coronary syndrome (ACS) in a real-world prospective study. Methods Patients with suspected ACS who underwent coronary angiography were included. Serum Neu5Ac was measured at admission. Coronary lesion severity was evaluated by Gensini Score. GRACE risk stratification was performed at admission. Major adverse cardiac events (MACEs) were recorded during follow-up. Results A total o

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Khan, Arshad A., Mohammed S. Al-Omary, Nicholas J. Collins, John Attia, and Andrew J. Boyle. "Natural history and prognostic implications of left ventricular end-diastolic pressure in reperfused ST-segment elevation myocardial infarction: an analysis of the thrombolysis in myocardial infarction (TIMI) II randomized controlled trial." BMC Cardiovascular Disorders 21, no. 1 (2021). http://dx.doi.org/10.1186/s12872-021-02046-x.

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Abstract Background The aim of the current study is to assess the natural history and prognostic value of elevated left ventricular end-diastolic pressure (LVEDP) in patients with ST-segment elevation myocardial infarction (STEMI) after reperfusion with thrombolysis; we utilize data from the Thrombolysis in Myocardial Infarction (TIMI) II study. Methods A total of 3339 patients were randomized to either an invasive (n = 1681) or a conservative (n = 1658) strategy in the TIMI II study following thrombolysis. To make the current cohort as relevant as possible to modern pharmaco-invasively manage

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Peng, Liming, Thiago Gagliano-Jucá, Karol M. Pencina, et al. "Age Trends in Growth and Differentiation Factor-11 and Myostatin Levels in Healthy Men, Measured Using Liquid Chromatography Tandem Mass Spectrometry: Differential Response to Testosterone." Journals of Gerontology: Series A, May 25, 2021. http://dx.doi.org/10.1093/gerona/glab146.

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Abstract Background Growth and differentiation factor (GDF)-11 controls embryonic development and has been proposed as an anti-aging factor. GDF-8 (myostatin) inhibits skeletal muscle growth. Difficulties in accurately measuring circulating GDF-11 and GDF-8 have generated controversy. Methods We developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for simultaneous measurement of circulating GDF-8 and GDF-11 that employs denaturation, reduction and alkylation; cation-exchange solid-phase extraction; tryptic digestion; followed by separation and quantification using two s

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