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Статті в журналах з теми "2C-value"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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1

Khan, Azmat Ali, Amer M. Alanazi, Nawaf Alsaif, Nasser Algrain, Tanveer Ahmad Wani, and Mashooq Ahmad Bhat. "Enhanced Efficacy of Thiosemicarbazone Derivative-Encapsulated Fibrin Liposomes against Candidiasis in Murine Model." Pharmaceutics 13, no. 3 (2021): 333. http://dx.doi.org/10.3390/pharmaceutics13030333.

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Candida albicans is the most studied species for the candidiasis infection and is becoming resistant towards existing antifungal drugs. Considering this, in the current study, we developed and characterized a fibrin liposome-based formulation encapsulating a novel thiosemicarbazone derivative, 2C, and evaluated its antifungal efficacy against murine candidiasis. The 2C-containing formulation was prepared by encapsulating 2C within the liposomes (2C-L) that were further encapsulated in the fibrin beads (2C-FL). The in-house synthesized 2C-FLs were spherical with a zeta potential of −34.12 ± 0.3

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2

Artico, Leonardo Luís, Ana Cristina Mazzocato, Juliano Lino Ferreira, Carlos Roberto Carvalho, and Wellington Ronildo Clarindo. "Karyotype characterization and comparison of three hexaploid species of Bromus Linnaeus, 1753 (Poaceae)." Comparative Cytogenetics 11, no. (2) (2017): 213–23. https://doi.org/10.3897/CompCytogen.v11i2.11572.

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Chromosome morphometry and nuclear DNA content are useful data for cytotaxonomy and to understand the evolutionary history of different taxa. For the genus Bromus Linnaeus, 1753, distinct ploidy levels have been reported, occurring from diploid to duodecaploid species. The geographic distribution of Bromus species has been correlated with chromosome number and ploidy level. In this study, the aims were to determine the nuclear genome size and characterize the karyotype of the South American Bromus species: Bromus auleticus Trinius ex Nees, 1829, Bromus brachyanthera Döll, 1878 and Bromus catha

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3

Maddaloni, Marianna, Rossella Farra, Barbara Dapas, et al. "In Vitro and In Vivo Evaluation of the Effects of Drug 2c and Derivatives on Ovarian Cancer Cells." Pharmaceutics 16, no. 5 (2024): 664. http://dx.doi.org/10.3390/pharmaceutics16050664.

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Background: The identification of novel therapeutic strategies for ovarian cancer (OC), the most lethal gynecological neoplasm, is of utmost urgency. Here, we have tested the effectiveness of the compound 2c (4-hydroxy-2,6-bis(4-nitrobenzylidene)cyclohexanone 2). 2c interferes with the cysteine-dependent deubiquitinating enzyme (DUB) UCHL5, thus affecting the ubiquitin-proteasome-dependent degradation of proteins. Methods: 2c phenotypic/molecular effects were studied in two OC 2D/3D culture models and in a mouse xenograft model. Furthermore, we propose an in silico model of 2c interaction with

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4

Kamaté, K., S. Brown, P. Durand, J. M. Bureau, D. De Nay, and T. H. Trinh. "Nuclear DNA content and base composition in 28 taxa of Musa." Genome 44, no. 4 (2001): 622–27. http://dx.doi.org/10.1139/g01-058.

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The nuclear DNA content of 28 taxa of Musa was assessed by flow cytometry, using line PxPC6 of Petunia hybrida as an internal standard. The 2C DNA value of Musa balbisiana (BB genome) was 1.16 pg, whereas Musa acuminata (AA genome) had an average 2C DNA value of 1.27 pg, with a difference of 11% between its subspecies. The two haploid (1C) genomes, A and B, comprising most of the edible bananas, are therefore of similar size, 0.63 pg (610 million bp) and 0.58 pg (560 million bp), respectively. The genome of diploid Musa is thus threefold that of Arabidopsis thaliana. The genome sizes in a set

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5

Munawaroh, Siti. "Peningkatan Hasil Belajar IPA Materi Getaran dan Gelombang melalui Metode Diskusi Kombinasi 2C B." Jurnal Pendidikan Madrasah 4, no. 2 (2020): 257–62. http://dx.doi.org/10.14421/jpm.2019.42-14.

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This research aims to: (1) to know the process of implementing learning that uses a combination discussion method 2C B can improve the results of science of vibration and wave material in the learners, (2) know the improvement of learning results IPA On wave vibration After a study using a combination discussion method of 2C B. The study uses class action research methods, consisting of two cycles with stages of planning, implementation, Observation and reflection. The research subject amounted to 31 students of class VIII-D MTs N 1 Yogyakarta with the method of collecting data using observati

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6

Amaral-Silva, Paulo Marcos, Wellington Ronildo Clarindo, Tatiana Tavares Carrijo, Carlos Roberto Carvalho, and Milene Miranda Praça-Fontes. "The contribution of cytogenetics and flow cytometry for understanding the karyotype evolution in three Dorstenia (Linnaeus, 1753) species (Moraceae)." Comparative Cytogenetics 10, no. (1) (2016): 97–108. https://doi.org/10.3897/CompCytogen.v10i1.6719.

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Chromosome morphometry and nuclear DNA content are useful data for cytotaxonomy and for understanding the evolutionary history of different taxa. However, the chromosome number is the only karyotype aspect reported for the species of Dorstenia so far. In this study, the nuclear genome size of Dorstenia arifolia (Lamarck, 1786), Dorstenia bonijesu (Carauta & C. Valente, 1983) and Dorstenia elata (Hooker, 1840) was evaluated and their karyotype morphometry accomplished, with the aim of verifying the potential of those parameters to understand evolutionary issues. Mean nuclear 2C value ranged

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7

Kayum, Mukadder, N. Kemal Koç, and Veli-Matti Rokka. "Variation of the Nuclear DNA Content of Species of Subtribe Citrinae (Rutaceae)." HortScience 33, no. 7 (1998): 1247–50. http://dx.doi.org/10.21273/hortsci.33.7.1247.

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Laser flow cytometry was used to analyze nuclear DNA contents (2C values) of five genera (Severinia Ten., Atalantia Corrèa, Fortunella Swing., Poncirus Raf., and Citrus L.) taxonomically grouped in subtribe Citrinae (citrus fruit trees) of the Rutaceae. The genotypes analyzed had 2C values ranging from 0.67 pg for diploid Severinia buxifolia (Poir.) Ten. to 1.27 pg for tetraploid Hongkong Fortunella hindsii Swing. There was no significant difference in the 2C values within the sexually compatible diploid species of 11 “true citrus fruit trees” [Citrus aurantium L., C. grandis (L.) Osbeck, C.

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8

Dekker, Luuk, Victor J. Geraedts, Hajo Hund, et al. "Importance of Reperfusion Status after Intra-Arterial Thrombectomy for Prediction of Outcome in Anterior Circulation Large Vessel Stroke." Interventional Neurology 7, no. 3-4 (2018): 137–47. http://dx.doi.org/10.1159/000486246.

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Background: Reperfusion status after intra-arterial thrombectomy (IAT) is a critical predictor of functional outcome after acute ischemic stroke. However, most prognostic models have not included a detailed assessment of reperfusion status after IAT. Objective: The aim of this work was to assess the association between successful reperfusion and clinical outcome. Methods: Clinical, radiological, and procedural variables of patients treated with IAT were extracted from our prospective stroke registry. The association with functional outcome using the modified Rankin Scale (mRS) after 3 months w

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9

ABUBAKAR, Sadiq Abdulhameed, and Andriy SVERSTYUK. "ANALYTICAL REVIEW OF PUBLICATIONS ON MACHINE LEARNING METHODS IN ONCOLOGY AND APPROACH TO EVALUATING THEIR QUALITY." Computer systems and information technologies, no. 1 (March 28, 2024): 6–16. http://dx.doi.org/10.31891/csit-2024-1-1.

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The work includes an analytical review of publications on machine learning methods in oncology and an approach to evaluating their quality. An analysis of publications by year was conducted in the Web of Science and Scopus bibliometric databases. The highest number of authors, the number of publications among universities, the number of countries, and publication categories in the Scopus bibliometric database on machine learning methods in oncology are presented. A multifactor regression prediction model for bone tissue density in oncological pathology predicting four severity grades of the st

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10

Carvalho, Renata Flávia de, Paulo Marcos Amaral-Silva, Micheli Sossai Spadeto, et al. "First karyotype description and nuclear 2C value for Myrsine (Primulaceae): comparing three species." Comparative Cytogenetics 11, no. (1) (2017): 163–77. https://doi.org/10.3897/CompCytogen.v11i1.11601.

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Cytogenetic studies in Primulaceae are mostly available for herbaceous species, and are focused on the chromosome number determination. An accurate karyotype characterization represents a starting point to know the morphometry and class of the chromosomes. Comparison among species within Myrsine, associating these data with the nuclear 2C value, can show changes that led the karyotype evolution. Here, we studied three Myrsine species [Myrsine coriacea (Swartz, 1788) Brown ex Roemer et Schultes, 1819, Myrsine umbellata Martius, 1841 and Myrsine parvifolia Candolle, 1841] that show different abi

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11

Almekhlafi, Mohammed A., Sachin Mishra, Jamsheed A. Desai, et al. "Not All “Successful” Angiographic Reperfusion Patients Are an Equal Validation of a Modified TICI Scoring System." Interventional Neuroradiology 20, no. 1 (2014): 21–27. http://dx.doi.org/10.15274/inr-2014-10004.

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Rapid reperfusion of the entire territory distal to vascular occlusions is the aim of stroke interventions. Recent studies defined successful reperfusion as establishing some perfusion with distal branch filling of <50% of territory visualized (Thrombolysis In Cerebral Infarction “TICI” 2a) or more. We investigate the importance of the quality of final reperfusion and whether a revision of the successful reperfusion definition is warranted. We retrospectively evaluated a prospective database of anterior circulation strokes treated using stentrievers to assess the quality of final reperfusio

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12

Dominguez, Mariana, Ignacio Echaide, Susana Torioni de Echaide, et al. "Validation and Field Evaluation of a Competitive Enzyme-Linked Immunosorbent Assay for Diagnosis of Babesia bovis Infections in Argentina." Clinical and Vaccine Immunology 19, no. 6 (2012): 924–28. http://dx.doi.org/10.1128/cvi.00015-12.

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ABSTRACTInfections byBabesia bovislimit cattle production and cause important economic losses in tropical and subtropical areas around the world. Monitoring of calf sera can be used to detect unprotected cattle herds and to decide on strategic control measures, as well as for epidemiological studies. Merozoite surface antigen 2c (MSA-2c) is an immunodominant surface protein expressed inB. bovismerozoites and sporozoites and contains B-cell epitopes that are conserved among geographic isolates. A monoclonal antibody against recombinant MSA-2c (rMSA-2c) was previously shown to inhibit the bindin

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13

Martins, Daniel, Carlos Fernandes, Ricardo F. Mendes, et al. "Bonding to Psychedelics: Synthesis of Molecularly Imprinted Polymers Targeting 4-Bromo-2,5-dimethoxyphenethylamine (2C-B)." Applied Sciences 14, no. 4 (2024): 1377. http://dx.doi.org/10.3390/app14041377.

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The increasing interest in utilizing psychedelics for therapeutic purposes demands the development of tools capable of efficiently monitoring and accurately identifying these substances, thereby supporting medical interventions. 4-Bromo-2,5-dimethoxyphenethylamine (2C-B) has gained significant popularity as one of the most widely used psychedelic compounds in non-medical settings. In this study, we aimed to create a material with selective recognition of 2C-B by synthesizing a series of molecularly imprinted polymers (MIP) using 2C-B as the template and varying ratios of methacrylic acid (MAA)

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14

Rampáčková, Eliška, Martina Mrázová, Jana Čížková, and Tomáš Nečas. "Pomological Traits and Genome Size of Prunus armeniaca L. Considering to Geographical Origin." Horticulturae 8, no. 3 (2022): 199. http://dx.doi.org/10.3390/horticulturae8030199.

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Apricot (Prunus armeniaca L.) is an important fruit crop and member of the Prunus genus of the Rosaceae family that is planted in many temperate regions worldwide. The quality of fruit is assessed by many pomological parameters which can serve as a decisive factor in apricot breeding, because the introduction of new cultivars is required. These parameters can differ with climate conditions, geographical location or geographic ecological origin. Similarly, another biological characteristic can be measured depending on these terms. The present study was conducted with the aim of estimating pomol

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15

Griyasti Suci, Windhu, Firman Asto Putro, Fandi Surya Adinata, Muhammad Nizam, Agus Ramelan, and Aida Nur Ramadhani. "Design and Implementation of DC Fast Charging for 48V LiFePO4 Battery Pack." E3S Web of Conferences 465 (2023): 02055. http://dx.doi.org/10.1051/e3sconf/202346502055.

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This research focuses on developing a fast charging system to charge lithium-ion battery packs with a voltage rating of 48 volts. Standard battery charging uses a 0.25 C charging rate, which takes about 4 hours. The charging method in this study uses the constant current, constant voltage (CC-CV) method by adjusting the charging current at a charging rate of 1C, 2C, and 3C from the battery capacity. The buck converter determined the charging current value, setting it to produce a voltage of 53 V and a charging current of 10 A for a 1C charging rate, 20 A for a 2C charging rate, and 30 A for a

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16

Rokka, Veli-Matti, Yong-Sheng Xu, Pirjo Tanhuanpää, Leena Pietilä, and Eija Pehu. "Electrofusion of protoplasts of anther-derived dihaploid lines of commercial potato cultivars." Agricultural and Food Science 5, no. 4 (1996): 449–60. http://dx.doi.org/10.23986/afsci.72756.

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Somatic hybrids of anther-derived dihaploid (2x) potato (Solanum tuberosum L.) lines were produced by electrofusion of protoplasts. Using RAPD (randomly amplified polymorphic DNA) markers, six new combinations of dihaploid parental lines from cultivars Matilda, Nicola, Pito, Stina, Van Gogh and White Lady were identified. RAPD marker identification of the putative hybrids was mostly done using two distinct parental line specific primers. 43% of the 76 regenerated calli from the six combinations produced hybrid shoots. Most of the somatic hybrids were tetraploid (4x), but in four fusion combina

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17

Rajan, Sandeep K. "Serum Thymidine Kinase (TK) Distinguishes Grade of Non Hodgkins Lymphoma (NHL) and Predicts Complete Response Rate (CRR) and Progression Free Survival (PFS)." Blood 104, no. 11 (2004): 4558. http://dx.doi.org/10.1182/blood.v104.11.4558.4558.

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Abstract Background: International Prognostic Index (IPI) based on clinical plus lab criteria help determine CRR and prognosis in lymphoma patients. However drawbacks exist and new markers to improve prognostication are sought for. TK is an enzyme involved in the DNA synthesis salvage pathway and can serve as a proliferative marker. Methods: Serum TK enzyme activity was determined using the Prolifigen TK radioenzymatic assay (Sangtec Medical,Sweden) in 58 consequetive NHL patients. All cases had conventional histopathologic and staging procedures and evaluation of IPI. Treatment was per instit

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18

Essad, S. "Mise en évidence de variations saltatoires de l'ADN nucléaire dans et entre les espèces du genre Medicago L." Genome 30, no. 5 (1988): 825–34. http://dx.doi.org/10.1139/g88-133.

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Forty-two samples representing 20 Medicago L. species were used to determine the nuclear DNA content of each species. Significant intra- and inter-specific variations were evident. The total amplitude of these variations at the 2C level ranged from 1.6 to 9.4 pg, but the maximum significant DNA evolutionary value amounted to 7.2 pg only (Medicago sativa 4x). The occurrence of two nuclear populations from a number of origins was interpreted as corresponding to a fundamental evolutionary value for one of them and to the addition of metabolic DNA for the other. All the values observed were near m

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19

Mu, Yun Chao, Bao Yan Liang, and Ji Feng Guo. "Effect of Sn and Si on the Synthesis of Ti₃Al(Sn/Si)C₂ by Self-Propagating High-Temperature Sintering." Advanced Materials Research 531 (June 2012): 342–45. http://dx.doi.org/10.4028/www.scientific.net/amr.531.342.

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The Ti3AlC2 was synthesized by self-propagating high-temperature sintering (SHS) using 3Ti/Al/2C powders as raw materials. Si or Sn was added to the raw materials in order to improve the synthesis reaction of Ti3AlC2. The result showed that the majority compounds were Ti3AlC2 and TiC in the synthesized sample. The content of Ti3AlC2 in the sample was approximate 59%. Si or Sn additives improved the synthesis of Ti3AlC2 obviously and the effect of Si additive in the reaction was much better than that of Sn. For raw materials of 3Ti/Al/2C/0.3Si, the content of Ti3AlC2 in the sample reached the m

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20

Carvalho, Renata Flávia de, Paulo Marcos Amaral-Silva, Micheli Sossai Spadeto, et al. "First karyotype description and nuclear 2C value for Myrsine (Primulaceae): comparing three species." Comparative Cytogenetics 11, no. 1 (2017): 163–77. http://dx.doi.org/10.3897/compcytogen.v11i1.11601.

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21

Musin, T. I., Z. A. Bagmanova, D. A. Gareev, V. G. Rudenko, and N. Sh Zagidullin. "Prediction of sinus rhythm maintenance after radiofrequency ablation in patients with atrial fibrillation using speckle tracking echocardiography and dynamics of left atrial structural and functional parameters." Russian Journal of Cardiology 26, no. 2S (2021): 4256. http://dx.doi.org/10.15829/1560-4071-2021-4256.

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Aim. To evaluate the dynamics of left atrial volume (LAV), strain (S) during the reservoir phase and strain rate (SR) in patients with paroxysmal and persistent atrial fibrillation (AF), scheduled for catheter radiofrequency ablation (RFA), as well as to compare the predictive value of S and SR as a marker of maintaining sinus rhythm.Material and methods. A total of 19 patients (men, 11; women, 8) aged 62±10,7 years with AF were included in the study, 13 (67%) of whom had persistent AF, while 6 patients (33%) had paroxysmal AF Two-dimensional and speckle tracking N. Sh. echocardiography (EPIQ

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22

Kenton, Ann, and Andrew Drakeford. "Genome size and karyotype evolution in Tradescantia section Cymbispatha (Commelinaceae)." Genome 33, no. 4 (1990): 604–10. http://dx.doi.org/10.1139/g90-089.

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Karyotype morphology and nuclear DNA content are compared in species of Tradescantia section Cymbispatha from North and South America. Comparison of DNA amounts confirms the polyploid ancestry previously suggested for several cytotypes and shows that basic genome size has been unaffected by the Robertsonian fusions constituting a major evolutionary change in this group. The 2C-values of Mexican tetraploids are double those of their Central American diploid relative Tradescantia gracillima. The 2C-value of the South American tetraploid T. cymbispatha is comparatively lower as a result of a redu

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23

Wiyono, Ketang, Kristylia Sury, Riski Nur Hidayah, Nauratun Nazhifah, Ismet Ismet, and Sudirman Sudirman. "STEM-based E-learning: Implementation and Effect on Communication and Collaboration Skills on Wave Topic." Jurnal Penelitian & Pengembangan Pendidikan Fisika 8, no. 2 (2022): 259–70. http://dx.doi.org/10.21009/1.08208.

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Communication and collaboration are essential skills that students must master in the 21st century. These skills can be raised and improved through systematic learning, such as the STEM approach. This study aims to determine the effect of STEM-based e-learning applications on high school students’ 2C (communication and collaboration) skills on wave material. This type of research was quasi-experimental, using the pretest-posttest method. The population of this study was 11th-grade students of the science program at public senior high school number 2 Palembang. Data analysis techniques used qua

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24

Morin, Hannah, Jay Whitacre, and Jeremy Michalek. "Electric Vehicle Battery Replacement Costs Under Realistic Fast Charging Behaviors." ECS Meeting Abstracts MA2023-01, no. 7 (2023): 2777. http://dx.doi.org/10.1149/ma2023-0172777mtgabs.

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Fast charging networks are being constructed in the United States based on the assumption that electric vehicles can sustainably fast charge. However, fast charging has been shown to shorten calendar and cycle life across multiple lithium-ion battery chemistries. Public information on degradation is limited for realistically fast charged commercial cells and extensions from academic work on commercial-adjacent chemistries is difficult. Here, we model realistic consumer charging behavior by cycling commercial NCA 21700 and LFP 26650 cells under 20 different fast charging behaviors, mixing fast

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Carrasco, Carlos J., Antonio Pastor, María del Mar Conejo, et al. "Synthesis, Characterization, and Preliminary In Vitro Anticancer Activity of Zinc Complexes Containing Amino Acid-Derived Imidazolium-Based Dicarboxylate Ligands." International Journal of Molecular Sciences 26, no. 7 (2025): 3202. https://doi.org/10.3390/ijms26073202.

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Coordination polymers containing zinc and imidazolium-based dicarboxylate ligands, [LR]−, were synthesized by reacting zinc acetate with HLR compounds, 1. The resulting complexes were characterized and structurally identified using single-crystal X-ray diffraction, revealing polymeric structures for the complexes [Zn(LR)2]n (R = Gly, 2a; βAla, 2b) and [Zn(LLeu)2(H2O)2]n (2c). In these structures, the [LR]− ligands adopt a bridging monodentate μ-κ1-O1,κ1-O3 coordination mode, resulting in distorted tetrahedral (2a, 2b) or octahedral (2c) geometries around the zinc center. When the synthesis was

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26

Marques, Anelise, Amélia Carlos Tuler, Carlos Roberto Carvalho, Tatiana Carrijo, Marcia Flores da Silva Ferreira, and Wellington Clarindo. "Refinement of the karyological aspects of Psidium guineense (Swartz, 1788): a comparison with Psidium guajava (Linnaeus, 1753)." Comparative Cytogenetics 10, no. (1) (2016): 117–28. https://doi.org/10.3897/CompCytogen.v10i1.6462.

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Euploidy plays an important role in the evolution and diversification of Psidium Linnaeus, 1753. However, few data about the nuclear DNA content, chromosome characterization (morphometry and class) and molecular markers have been reported for this genus. In this context, the present study aims to shed light on the genome of Psidium guineense Swartz, 1788, comparing it with Psidium guajava Linnaeus, 1753. Using flow cytometry, the nuclear 2C value of P. guineense was 2C = 1.85 picograms (pg), and the karyotype showed 2n = 4x = 44 chromosomes. Thus, P. guineense has four chromosome sets, in acco

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27

Abreu, Isabella Santiago, Carlos Roberto Carvalho, Guilherme Mendes Almeida Carvalho, and Sérgio Yoshimitsu Motoike. "First karyotype, DNA C-value and AT/GC base composition of macaw palm (Acrocomia aculeata, Arecaceae) - a promising plant for biodiesel production." Australian Journal of Botany 59, no. 2 (2011): 149. http://dx.doi.org/10.1071/bt10245.

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The oleaginous species Acrocomia aculeata produces high-quality oil and is considered a potential plant for sustainable production of food and biodiesel. In spite of its economical, social and environmental importance, few data concerning the genome size and chromosomal characterisation of this crop have been reported. In order to contribute to basic genetic knowledge on A. aculeata, this work aimed to assemble the first karyogram and to determine genome size and base composition of this species. Concerning the cytogenetic approach, we developed a protocol based on root tips treatment with an

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28

Singh, K. P., S. N. Raina, and A. K. Singh. "Variation in chromosomal DNA associated with the evolution of Arachis species." Genome 39, no. 5 (1996): 890–97. http://dx.doi.org/10.1139/g96-112.

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The 2C nuclear DNA amounts were determined for 99 accessions, representing 23 Arachis species from 8 of 9 taxonomic sections, and two synthetic amphidiploids. Mean 2C DNA amounts varied by 15.20%, ranging from 10.26 to 11.82 pg, between accessions of Arachis hypogaea (2n = 4x = 40). Nuclear DNA content variation (5.33–5.91 pg) was also detected among Arachis duranensis (2n = 2x = 20) accessions. The intraspecific variation in the two species may have resulted from indirect selection for favourable genome sizes in particular environmental conditions. The accessions belonging to A. hypogaea ssp.

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Kerr, Ava, Gary J. Slater, and Nuala Byrne. "Impact of food and fluid intake on technical and biological measurement error in body composition assessment methods in athletes." British Journal of Nutrition 117, no. 4 (2017): 591–601. http://dx.doi.org/10.1017/s0007114517000551.

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AbstractTwo, three and four compartment (2C, 3C and 4C) models of body composition are popular methods to measure fat mass (FM) and fat-free mass (FFM) in athletes. However, the impact of food and fluid intake on measurement error has not been established. The purpose of this study was to evaluate standardised (overnight fasted, rested and hydrated) v. non-standardised (afternoon and non-fasted) presentation on technical and biological error on surface anthropometry (SA), 2C, 3C and 4C models. In thirty-two athletic males, measures of SA, dual-energy X-ray absorptiometry (DXA), bioelectrical i

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30

Roma, Elia, Elena Mattoni, Paolo Lupattelli, et al. "New Dihydroxytyrosyl Esters from Dicarboxylic Acids: Synthesis and Evaluation of the Antioxidant Activity In Vitro (ABTS) and in Cell-Cultures (DCF Assay)." Molecules 25, no. 14 (2020): 3135. http://dx.doi.org/10.3390/molecules25143135.

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New dihydroxytyrosyl esters 2a, 2c–2j of dicarboxylic acids were synthesized from methyl orthoformate protected hydroxytyrosol 3 and diacyl chlorides. New compounds were characterized (HRMS, FT-IR, 1H- and 13C-NMR), and tested for antioxidant activity both in vitro (ABTS) and on L6 myoblasts and THP1 leukemic monocytes cell culture by DCF assay. According to the ABTS assay, compounds 2a, 2c–2j showed a TEAC value of antioxidant capacity up to twice that of Trolox. Very high or complete ROS protections were obtained in the cell environment where lipophilicity and rigidity of dicarboxylic struct

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31

Carloni-Jarrys, Edgardo J., Ma Cristina Acosta-Bragato, and Karina Grunberg-Fraga. "NUCLEAR DNA CONTENT AND PLOIDY LEVEL IN APOMICTIC BUFFELGRASS GENOTYPES." Revista Fitotecnia Mexicana 41, no. 1 (2018): 23–29. http://dx.doi.org/10.35196/rfm.2018.1.23-29.

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Buffelgrass [Pennisetum ciliare (L.) Link syn. Cenchrus ciliaris L.] is a polyploid fodder grass that reproduces mostly via apomixis. The wide genomic and cytological diversity present in the species indicates that the active field collection at Instituto de Fisiología y Recursos Genéticos Vegetales (IFRGV) of the National Institute of Agricultural Technology (INTA) might contain individuals with different ploidy levels. This researche aimed to determine nuclear DNA content and ploidy level of introduced apomictic germplasm of buffelgrass. Cytological studies showed different ploidy levels in

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32

Zinah Abdulhameed Alobaidi and Samer Imad Mohammed. "Olanzapine-induced Metabolic Syndrome and its Association with -759C>T Polymorphism of the HTR2C Gene in Iraqi Schizophrenic Patients." Iraqi Journal of Pharmaceutical Sciences( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 33, no. 3 (2024): 37–46. http://dx.doi.org/10.31351/vol33iss3pp37-46.

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The hazardous metabolic effects of treating schizophrenia patients with olanzapine comprise serotonin 2C receptor (5-HT2C) antagonists. Metabolic side effects of antipsychotic drugs, including lipid abnormalities, disturbed glucose metabolism, and weight gain, can have a major impact on treating psychiatric patients. The intent of this study was to investigate whether there is an associated link between the genetic polymorphism at -759C>T in the promoter region of the 5-hydroxytryptamine 2C receptor (HTR2C) gene and the metabolic syndrome driven by olanzapine in schizophrenia patients. A cr

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33

Poláková, Katarína, Alica Bobková, Alžbeta Demianová, et al. "Quality Attributes and Sensory Acceptance of Different Botanical Coffee Co-Products." Foods 12, no. 14 (2023): 2675. http://dx.doi.org/10.3390/foods12142675.

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Coffee processing is a major contributor to the creation of food and product waste. Using coffee co-products can play an essential role in addressing environmental problems and issues with nutritionally unbalanced foods, population growth, and food-related diseases. This research aimed to determine the quality and sensory parameters (aw, pH, dry matter, TAC, TPC, fat, fatty acids profile, fiber, caffeine, chlorogenic acids, color, and sensory analysis) of different botanical origins of cascara (coffee husks) and silverskin (thin layer). The results of this study show that silverskin and cascar

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34

Takvorian, Najat, Hamissou Zangui, Abdel Kader Naino Jika, Aïda Alouane, and Sonja Siljak-Yakovlev. "Genome Size Variation in Sesamum indicum L. Germplasm from Niger." Genes 15, no. 6 (2024): 711. http://dx.doi.org/10.3390/genes15060711.

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Sesamum indicum L. (Pedaliaceae) is one of the most economically important oil crops in the world, thanks to the high oil content of its seeds and its nutritional value. It is cultivated all over the world, mainly in Asia and Africa. Well adapted to arid environments, sesame offers a good opportunity as an alternative subsistence crop for farmers in Africa, particularly Niger, to cope with climate change. For the first time, the variation in genome size among 75 accessions of the Nigerien germplasm was studied. The sample was collected throughout Niger, revealing various morphological, biochem

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35

Kozlowski, Gregor, Yann Fragnière, Benoît Clément, and Conor Meade. "Genome Size in the Arenaria ciliata Species Complex (Caryophyllaceae), with Special Focus on A. ciliata subsp. bernensis, a Narrow Endemic of the Swiss Northern Alps." Plants 11, no. 24 (2022): 3489. http://dx.doi.org/10.3390/plants11243489.

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The genus Arenaria (Caryophyllaceae) comprises approximately 300 species worldwide; however, to date, just six of these taxa have been investigated in terms of their genome size. The main subject of the present study is the A. ciliata species complex, with special focus on A. ciliata subsp. bernensis, an endemic plant occurring in the Swiss Northern Alps. Altogether, 16 populations and 77 individuals of the A. ciliata complex have been sampled and their genome sizes were estimated using flow cytometry, including A. ciliata subsp. bernensis, A. ciliata s.str., A. multicaulis, and A. gothica. Th

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36

ACAR ÇEVİK, Ulviye, and Tugba ERCETİN. "Design, Synthesis and Evaluation of Pyrrol-thiazole Derivatives as AChE and BuChE Inhibitory and Antioxidant Activities." Cumhuriyet Science Journal 44, no. 4 (2023): 625–28. http://dx.doi.org/10.17776/csj.1255826.

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Thiazole rings are one of the most frequently used heterocyclic moieties and are found in a wide variety of biologically active chemicals. In this research project, we report the synthesis and biological activities of some new thiazole derivatives (2a-2c) as potent anti-Alzheimer’s agents. These final compounds’ structures were characterized by spectral (1H NMR, 13C NMR, and MS spectra) analyses. The highest inhibitory activity against AChE was demonstrated by compound 2c (23.73 ± 0.018 %) with chloro substitution at the meta and para positions of the phenyl ring, while the highest inhibitory

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37

Mu, Yi, Pengfei Cai, Remigio M. Olveda, Allen G. Ross, David U. Olveda, and Donald P. McManus. "Parasite-derived circulating microRNAs as biomarkers for the detection of human Schistosoma japonicum infection." Parasitology 147, no. 8 (2019): 889–96. http://dx.doi.org/10.1017/s0031182019001690.

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AbstractNovel tools for early diagnosis and monitoring of schistosomiasis are urgently needed. This study aimed to validate parasite-derived miRNAs as potential novel biomarkers for the detection of human Schistosoma japonicum infection. A total of 21 miRNAs were initially validated by real-time-polymerase chain reaction (RT-PCR) using serum samples of S. japonicum-infected BALB/c mice. Of these, 6 miRNAs were further validated with a human cohort of individuals from a schistosomiasis-endemic area of the Philippines. RT-PCR analysis showed that two parasite-derived miRNAs (sja-miR-2b-5p and sj

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38

Zoldos, V., D. Papes, S. C. Brown, O. Panaud, and S. Siljak-Yakovlev. "Genome size and base composition of seven Quercus species: inter- and intra-population variation." Genome 41, no. 2 (1998): 162–68. http://dx.doi.org/10.1139/g98-006.

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Seven Quercus species, four deciduous (Q. cerris, Q. petraea, Q. pubescens, andQ. robur) and three evergreen (Q. coccifera, Q. ilex, andQ. suber), were assessed for DNA content. Their genome sizes ranged from 1.88 to 2.00 pg/2C, namely an interspecific DNA content variation of 6%. In addition, the DNA content of several populations of Q. petraea andQ. robur with different geographical origins, French and Croatian, was estimated. DNA content did not vary among four populations of Q. robur, but did differ between two populations of Q. petraea, the French population having a higher 2C DNA value t

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39

Sonawane, V. D., B. D. Sonawane, M. J. Dhanavade, K. D. Sonawane, and R. B. Bhosale. "Design, Synthesis, Characterization, Anti-Inflammatory and Antioxidant Evaluation of Certain Novel Pyrazoline Derivatives Containing Imidazo[2,1-b]thiazole Moiety." Asian Journal of Organic & Medicinal Chemistry 5, no. 1 (2020): 45–50. http://dx.doi.org/10.14233/ajomc.2020.ajomc-p233.

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In present study, a novel series of substituted imidazo[2,1-b]thiazole pyrazoline derivatives (2a-e) and (3a-e) from the reference compound imidazo[2,1-b]thiazole chalcones (1a-e) in PEG-400 by using hydrazine hydrate and phenyl hydrazine was synthesized. Characterization of newly synthesized compounds was done using IR and 1H NMR. Further, imidazo[2,1-b]thiazole pyrazoline derivatives were subjected to check their in vitro antioxidant activities at a concentration of 0.5 mmol/L in methanol. Compounds 2c, 2d, 3c, 3d and 3e showed comparatively good activity than standard drug diclofenac. The a

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Fentaw, Mulugeta, Esayas Alemayehu, and Anteneh Geremew. "EXPERIMENTAL STUDY OF STABILIZATION OF EXPANSIVE SOIL USING THE MIXTURE OF MARBLE DUST, RICE HUSK ASH AND CEMENT FOR SUB-GRADE ROAD CONSTRUCTION: A CASE STUDY OF WOLDIA TOWN." Journal of Civil Engineering, Science and Technology 12, no. 2 (2021): 141–59. http://dx.doi.org/10.33736/jcest.3977.2021.

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Understanding the behavior of expansive soil and adopting the appropriate control measures should be great for civil engineers. Extensive research has been going on to find the solutions associated with problems of expansive soils. There have been many methods available to control the expansiveness of these soils. The removal of expansive soils and replacement with suitable material has been widely practiced worldwide. Reasonable material is available within economic distances; however, suitable materials is not readily an available in urban areas for borrowing, which has to be hauled from a l

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Lumbiny, Bilkis Jahan, Zhang Hui, and M. Azizul Islam. "Antiaging, antioxidant flavonoids; synthesis, antimicrobial screening as well as 3D QSAR CoMFA models for the prediction of biological activity." Journal of the Asiatic Society of Bangladesh, Science 39, no. 2 (2014): 191–99. http://dx.doi.org/10.3329/jasbs.v39i2.17856.

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Flavonoids, polyphenolic heteronuclear compounds which are naturally occurring antioxidants are widely used as antiaging substances. Synthesis of new naturally occuring organic compounds with basic skeleton of chalcones, flavones and oxygenated flavones and their antimicrobial activity were reported by this research group for long. Presently comparative molecular field analysis (CoMFA) implemented in Sybyl 7.3 was conducted on a series of substituted flavones. CoMFA is an effective computer implemented 3D QSAR technique deriving a correlation between set of the biologically active molecules an

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42

Cardoso, Monique Herrera, Sheila Henderson, and Simone Aparecida Capellini. "Translation and cultural adaptation of Brazilian Detailed Assessment of Speed of Handwriting: conceptual and semantic equivalence." Audiology - Communication Research 19, no. 4 (2014): 321–26. http://dx.doi.org/10.1590/s2317-64312014000400001447.

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Purpose To perform the translation and cultural adaptation of the Detailed Assessment of Speed of Handwriting (DASH) for the Brazilian population. Methods (1) Evaluation of conceptual and items equivalence, and (2) Semantic equivalence, including the steps of (2a) Translation, (2b) retranslation, (2c) Review by the committee of judges and (2d) Pre-test. The second step was carried out by two professionals and 2b by two other professionals, 2c was formed by speech therapists, occupational therapists and educators and the 2d was carried out with 32 students, four from each age group (9-16 years

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43

Idris, Hadeil M. E., Hiba B. Khalil, Jeremy Mills, and Abozer Y. Elderdery. "CYP1A1 and CYP2D6 Polymorphisms and Susceptibility to Chronic Myelocytic Leukaemia." Current Cancer Drug Targets 20, no. 9 (2020): 675–80. http://dx.doi.org/10.2174/1570163817666200518081356.

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Background: CYP1A1 and CYP2D6 are both xenobiotic metabolizing enzymes belonging to the CYP450 enzyme family. Polymorphisms in these genes vary between individuals, resulting in dissimilar patterns of susceptibility to the effects of carcinogenic substances and drugs. Objective: In a prospective study, the influence of CYP1A1*2C and CYP2D6*4 gene polymorphisms on the susceptibility to chronic myelocytic leukaemia (CML) were investigated. Methods: Prevalence of CYP1A1*2C and CYP2D6*4 was detected in blood specimens from three hundred participants - two hundred patients and a hundred healthy ind

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An, Zhiyuan, Peng Chen, Fucai Tang, Xueying Yang, Rong Wang, and Zhihao Wang. "Evaluating the Performance of Seven Ongoing Satellite Altimetry Missions for Measuring Inland Water Levels of the Great Lakes." Sensors 22, no. 24 (2022): 9718. http://dx.doi.org/10.3390/s22249718.

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Satellite altimetry can provide long-term water level time series for water bodies lacking hydrological stations. Few studies have evaluated the performance of HY-2C and Sentinel-6 satellites in inland water bodies, as they have operated for less than 1 and 2 years, respectively. This study evaluated the measured water level accuracy of CryoSat-2, HY-2B, HY-2C, ICESat-2, Jason-3, Sentinel-3A, and Sentinel-6 in the Great Lakes by in-situ data of 12 hydrological stations from 1 January 2021 to 1 April 2022. Jason-3 and Sentinel-6 have the lowest mean root-mean-square-error (RMSE) of measured wat

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Garcia, Sònia, Teresa Garnatje, John D. Twibell, and Joan Vallès. "Genome size variation in the Artemisia arborescens complex (Asteraceae, Anthemideae) and its cultivars." Genome 49, no. 3 (2006): 244–53. http://dx.doi.org/10.1139/g05-105.

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Different wild Mediterranean populations of Artemisia arborescens from diverse locations representing its geographical distribution, as well as some of its well-known cultivars and some specimens cultivated as ornamentals in gardens, streets, roads and nurseries, were analysed for genome size. Other closely related species endemic to Macaronesia, Artemisia canariensis, Artemisia argentea, and Artemisia gorgonum, were also analysed, and their nuclear DNA amount has been related to the biogeography of this group of species. Additionally, 5 populations of the closely related Artemisia absinthium

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Macháčková, Petra, Ľuboš Majeský, Michal Hroneš, Eva Hřibová, Bohumil Trávníček, and Radim J. Vašut. "New chromosome counts and genome size estimates for 28 species of Taraxacum sect. Taraxacum." Comparative Cytogenetics 12, no. 3 (2018): 403–20. http://dx.doi.org/10.3897/compcytogen.v12i3.27307.

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The species-rich and widespread genusTaraxacumF. H. Wiggers, 1780 (Asteraceae subfamily Cichorioideae) is one of the most taxonomically complex plant genera in the world, mainly due to its combination of different sexual and asexual reproduction strategies. Polyploidy is usually confined to apomictic microspecies, varying from 3x to 6x (rarely 10x). In this study, we focused on Taraxacum sect.Taraxacum(= T.sect.Ruderalia;T.officinalegroup), i.e., the largest group within the genus. We counted chromosome numbers and measured the DNA content for species sampled in Central Europe, mainly in Czech

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47

Mitrenina, Elizaveta Yu, Andrey S. Erst, Michail V. Skaptsov, et al. "Karyotype and genome size in Adonis vernalis and Adonis volgensis." Turczaninowia 25, no. 1 (2022): 5–15. http://dx.doi.org/10.14258/turczaninowia.25.1.1.

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The comparative karyological analysis of Adonis vernalis and Adonis volgensis (Ranunculaceae) from 11 populations from Russia (Altai Territory, Novosibirsk Region, Republic of Khakassia) and Bulgaria was carried out. The somatic chromosome number was 2n = 16 in all studied plants. Chromosome sets of A. vernalis from the Altai Territory (near Sibirskiye Ogni village) and the Republic of Khakassia (Tashtipskiy District), A. volgensis from the Altai Territory (near Chernopyatovo village) and Bulgaria (Kavarna Municipality) consist of eight metacentric and eight submetacentric chromosomes. Two pai

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Heymsfield, Andrew, Martina Krämer, Norman B. Wood, Andrew Gettelman, Paul R. Field, and Guosheng Liu. "Dependence of the Ice Water Content and Snowfall Rate on Temperature, Globally: Comparison of in Situ Observations, Satellite Active Remote Sensing Retrievals, and Global Climate Model Simulations." Journal of Applied Meteorology and Climatology 56, no. 1 (2017): 189–215. http://dx.doi.org/10.1175/jamc-d-16-0230.1.

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AbstractCloud ice microphysical properties measured or estimated from in situ aircraft observations are compared with global climate models and satellite active remote sensor retrievals. Two large datasets, with direct measurements of the ice water content (IWC) and encompassing data from polar to tropical regions, are combined to yield a large database of in situ measurements. The intention of this study is to identify strengths and weaknesses of the various methods used to derive ice cloud microphysical properties. The in situ data are measured with total water hygrometers, condensed water p

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Maryana, Maryana, Indah Hidayah Putri, and Sepriadi Sepriadi. "PENERAPAN METODE SIMPLEKS DENGAN MICROSOFT EXCEL SOLVER UNTUK OPTIMALISASI BLENDING BATUBARA SESUAI KRITERIA KONSUMEN." Proximal: Jurnal Penelitian Matematika dan Pendidikan Matematika 8, no. 2 (2025): 614–21. https://doi.org/10.30605/proximal.v8i2.5793.

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Batubara yang tersedia sering kali tidak sesuai dengan kriteria konsumen dan perusahaan dituntut untuk memenuhi kriteria konsumen tersebut. Jika batubara yang dijual tidak sesuai kesepakatan maka konsumen berhak membatalkan kontrak ataupun memberikan pengurangan harga kepada perusahaan. Salah seorang konsumen PT X membutuhkan batubara dengan kriteria kualitas sebagai berikut ash (ASH) 6,50 %, total moisture (TM) 49 %, total sulphur (TS) 0,80 % dan calorific value (CV) 3200 kkal/kg. Untuk menyesuaikan kriteria kualitas yang diinginkan konsumen perlu dilakukan pencampuran (blending) batubara. Tu

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Akbarzadeh, Mehrdad, Katrijn Van Laere, Leen Leus, et al. "Can Knowledge of Genetic Distances, Genome Sizes and Chromosome Numbers Support Breeding Programs in Hardy Geraniums?" Genes 12, no. 5 (2021): 730. http://dx.doi.org/10.3390/genes12050730.

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Breeding programs in ornamentals can be facilitated by integrating knowledge of phylogenetic relatedness of potential parents along with other genomic information. Using AFLP, genetic distances were determined for 59 Geranium genotypes, comprising 55 commercial cultivars of the three subgenera of a total collection of 61 Geranium genotypes. A subgroup of 45 genotypes, including intragroup and intergroup hybrids, were selected and further characterized for genome sizes and chromosome numbers. The variation in genome size ranged from 1.51 ± 0.01 pg/2C to 12.94 ± 0.07 pg/2C. The chromosome number

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