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Статті в журналах з теми "340.14 (043.2)"

Автор: Grafiati

Опубліковано: 30 травня 2022

Оновлено: 31 липня 2025

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1

Rimer, Ernest G., Linda R. Peterson, Andrew R. Coggan, and James C. Martin. "Increase in Maximal Cycling Power With Acute Dietary Nitrate Supplementation." International Journal of Sports Physiology and Performance 11, no. 6 (2016): 715–20. http://dx.doi.org/10.1123/ijspp.2015-0533.

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Muscle-shortening velocity and hence power have been shown to increase in the presence of nitric oxide (NO). NO availability increases after consuming nitrate (NO3-). Ingestion of NO3-rich beetroot juice (BRJ) has increased muscle power in untrained adults.Purpose:This study determined whether NO3- supplementation could acutely enhance maximal power in trained athletes.Methods:In this double-blind, crossover study, 13 trained athletes performed maximal inertial-load cycling trials (3–4 s) immediately before (PRE) and after (POST) consuming either NO3-rich (NO3) or NO3-depleted (PLA) BRJ to ass

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2

Lucas, C., S. Rodriguez, R. Jean, et al. "AB0034 EARLY IMMUNIZATION AGAINST TREATMENT IS ASSOCIATED TO POOR CLINICAL RESPONSE AT 6 MONTHS AND LOW NUMBER OF TRANSITIONAL B CELLS AT BASELINE IN RHEUMATOID ARTHRITIS PATIENTS TREATED BY ADALIMUMAB." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1319.1–1320. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3938.

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Background:Circulating anti-drug antibodies (ADAs) are detectable approximatively in 33% of adalimumab treated rheumatoid arthritis (RA) patients, often within the first 6 months of therapy1-2. Classically, circulating ADAs associate with their specific drugs to form immune complexes, increasing drug clearance, and by this mechanism reducing therapeutic effect3. B cell involvement leading to ADAs production is not yet well established.Objectives:To study early ADAs formation according to clinical response to an adalimumab therapy in RA patients and the relationship between ADAs and circulating

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3

McKee, P. M., W. J. Snodgrass, D. R. Hart, H. C. Duthie, J. H. McAndrews, and W. Keller. "Sedimentation Rates and Sediment Core Profiles of 238U and 232Th Decay Chain Radionuclides in a Lake Affected by Uranium Mining and Milling." Canadian Journal of Fisheries and Aquatic Sciences 44, no. 2 (1987): 390–98. http://dx.doi.org/10.1139/f87-048.

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Radionuclide concentration profiles in sediment cores from three deep basins of Quirke Lake, Ontario, showed enrichment in the surficial layers related to the period of uranium mining in the watershed, based on sedimentation rates determined from a milling-related pH decline indicated by fossil diatoms. Recent sedimentation rates are 96 ± 7 to 185 ± 14 g∙m−2∙yr−1. 210Pb profiles could not be used to determine sedimentation rates due to loadings of 226Ra and 210Ph from mining and milling activities. Profiles of 238U and 232Th decay chain radionuclides showed an enrichment of 1–3 orders of magni

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4

Rhind, S. M., B. A. Morris, Jill Clayton, and G. Gittus. "Effect of level of food intake at mating on the reproductive performance of ewes passively immunized against testosterone." Animal Science 45, no. 1 (1987): 81–85. http://dx.doi.org/10.1017/s0003356100036655.

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AbstractIn a 2 × 2 × 2 experiment, 296 Scottish Blackface ewes were fed to achieve one of two levels of body condition (high: condition scores ^2·75; low: condition scores ^2·50) by 2 weeks before joining with rams. Half of the ewes of each condition score were fed dried grass pellets ad libitum and 300 g hay per head daily, between 2 weeks before and 8 days after joining, while the remaining ewes were offered a live-weight maintenance ration comprising 750 g pellets and 400 g hay per head daily. From 8 days after joining the intake of all ewes was gradually changed, over a 2-week period, to 1

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5

Shinozuka, Y., J. Redemann, J. M. Livingston, et al. "Airborne observation of aerosol optical depth during ARCTAS: vertical profiles, inter-comparison and fine-mode fraction." Atmospheric Chemistry and Physics 11, no. 8 (2011): 3673–88. http://dx.doi.org/10.5194/acp-11-3673-2011.

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Abstract. We describe aerosol optical depth (AOD) measured during the Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS) experiment, focusing on vertical profiles, inter-comparison with correlative observations and fine-mode fraction. Arctic haze observed in <2 km and 2–4 km over Alaska in April 2008 originated mainly from anthropogenic emission and biomass burning, respectively, according to aerosol mass spectrometry and black carbon incandescence measurements. The Ångström exponent for these air masses is 1.4 ± 0.3 and 1.7 ± 0.1, respectively, when

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6

Bowmaker, Graham A., Effendy, Robert D. Hart, John D. Kildea, and Allan H. White. "Lewis-Base Adducts of Group 11 Metal(I) Compounds. LXXIII Synthesis, Spectroscopy and Structural Systematics of New 1 : 1 'Cubane' Tetramers of Copper(I) and Silver(I) Halides with Triphenylarsine." Australian Journal of Chemistry 50, no. 6 (1997): 653. http://dx.doi.org/10.1071/c96039.

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Syntheses and room-temperature single-crystal X-ray structural characterization of a number of 1 : 1 ‘cube tetramer’ adducts of copper(I) and silver(I) halides, MX, with triphenylarsine, AsPh3, are recorded, being [XM(AsPh3)]4. The CuBr adduct, obtained unsolvated from toluene, orthorhombic Pbcn, a 17·844(5), b 20·778(8), c 18·430(4) Å, Z = 4 tetramers, conventional R on |F| 0·058 for No 1309 independent ‘observed’ reflctions (I > 3σ(I)), is isomorphous with previously recorded [ClAg(PPh3)]4, the tetramer having crystallographically imposed 2 symmetry. The CuI adduct, previously recorded as

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7

Campbell, Ciara, Declan Millett, Niamh Kelly, Marie Cooke, and Michael Cronin. "Frankel 2 appliance versus the Modified Twin Block appliance for Phase 1 treatment of Class II division 1 malocclusion in children and adolescents: A randomized clinical trial." Angle Orthodontist 90, no. 2 (2019): 202–8. http://dx.doi.org/10.2319/042419-290.1.

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ABSTRACT Objective: To compare Phase 1 treatment, using the Frankel 2 (FR2) or the modified Twin Block (MTB), for Class II division 1 malocclusion in children and adolescents with respect to: treatment duration, number of appliance breakages, occlusal outcome, and patient and parent perspectives. Materials and Methods: Sixty participants with a Class II division 1 malocclusion were randomly assigned to either the FR2 or MTB appliance in a two-armed parallel randomized clinical trial with an allocation ratio of 1 to 1. Time to achieve a Class I incisor relationship was the primary outcome. The

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8

Mills, John, Julia Mantey, Marco Cassone, Keith Kaye, and Lona Mody. "Low function and frequent readmission in nursing home patients with persistent resistant gram-negative bacterial colonization." Antimicrobial Stewardship & Healthcare Epidemiology 2, S1 (2022): s53—s54. http://dx.doi.org/10.1017/ash.2022.158.

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Background: Persistent colonization with resistant gram-negative bacteria (R-GNB) increases risk of clinical infection and intra-facility transmission among nursing home (NH) patients. Limited data exist on the roles of age and function on duration of R-GNB colonization. Methods: Secondary data analysis was performed from a cohort study of patients admitted to 6 Michigan NHs between November 2013 and May 2018. Swabs obtained upon enrollment, day 14, day 30, then monthly until NH discharge from 6 anatomical sites were cultured for GNB. R-GNB were defined as resistant to ciprofloxacin, ceftazidi

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9

Ejaz, Sameen, Maryam Ejaz, Umme Kalsoom, Maha Kamran, Deeba Ahsan, and Samina Qamar. "Study of Histopathological Pattern of Endometrial Curettings and Healthcare Burden due to Inadequate Samples." Pakistan Journal of Medical and Health Sciences 16, no. 4 (2022): 36–39. http://dx.doi.org/10.53350/pjmhs2216436.

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Aim: To determine the frequency of different histopathological findings of endometrial curettings presenting to a tertiary care hospital with a special focus on the frequency of inadequate samples which impose a major healthcare burden. Methods: The data of 975 female patients whose EC samples were received in the Pathology Lab of King Edward Medical University (KEMU), Lahore from August 2019- August 2021 was included in this retrospective, descriptive study. A statistical analysis of endometrial findings according to age and their association with histopathological findings was determined. Re

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10

Huber, Sandra, Stephan Hutter, Constance Regina Baer, et al. "Similarities and Differences of DNMT3A, TET2 and ASXL1 Mutations across Ccus, MDS and AML." Blood 144, Supplement 1 (2024): 1819. https://doi.org/10.1182/blood-2024-200561.

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Background: The most frequently mutated genes in clonal hematopoiesis (CH) occurring during aging are DNMT3A, TET2, and ASXL1 (DTA). DTA mutations (mut) also recurrently occur in overt myeloid malignancies. Aim: Analyze similarities and differences regarding incidence, co-aberrations and clonal hierarchy across CCUS, MDS and AML in patients with DTAmut. Methods: We analyzed 1,604 samples (received 2005-2021) of patients (median age: 71 years [2-93]; female: 42%) diagnosed with CCUS (n=222) or a non-therapy related myeloid malignancy (MDS: n=637; AML: n=745). All samples were analyzed by WGS (m

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11

Lin, Jeffrey, Amir Mortazavi, Mark N. Stein, et al. "Combined FDG and NaF PET/CT study in patients (pts) with metastatic genitourinary tumors (mGU) treated with cabozantinib + nivolumab +/- ipilimumab (CaboNivo+/-Ipi)." Journal of Clinical Oncology 35, no. 15_suppl (2017): e16017-e16017. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e16017.

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e16017 Background: The primary objective of the study is to assess the feasibility of obtaining combined FDG and NaF PET/CT in detecting soft-tissue and bone metastatic disease in mGU pts treated with CaboNivo+/-Ipi. Methods: Pts in this single-arm, multicenter, phase I trial had FDG PET/CT followed by NaF PET/CT within 1 hour, at baseline and 8 weeks. The number and location of metastatic lesions on FDG PET/CT and on NaF PET/CT were captured. Lesions were considered positive when there was focal abnormal radiotracer uptake with CT correlation. We analyzed soft tissue and bone lesions distribu

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12

Pinglot, J. F., M. Pourchet, B. Lefauconnier, and M. Creseveur. "Equilibrium line and mean annual mass balance of Finsterwalderbreen, Spitsbergen, determined by in situ and laboratory gamma-ray measurements of nuclear test deposits." Annals of Glaciology 24 (1997): 54–59. http://dx.doi.org/10.3189/s0260305500011939.

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In order to determine the equilibrium line (EL) and the annual net mass balance over the accumulation area of Finsterwalderbreen, Spitsbergen, Svalbard (by detection of the 1962–63 radioactive peak from the 1961–62 atmospheric nuclear tests), we collected 14 ice cores, at elevations of 445–730 m, in the springs of 1994 and 1995. The corresponding samples were melted and filtered for laboratory gamma spectrometry. In the accumulation area, the 1962–63 radioactive layer is found well below the surface. The mean annual accumulation is not invariably related to altitude. The EL, averaged to 545 in

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13

Pinglot, J. F., M. Pourchet, B. Lefauconnier, and M. Creseveur. "Equilibrium line and mean annual mass balance of Finsterwalderbreen, Spitsbergen, determined by in situ and laboratory gamma-ray measurements of nuclear test deposits." Annals of Glaciology 24 (1997): 54–59. http://dx.doi.org/10.1017/s0260305500011939.

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In order to determine the equilibrium line (EL) and the annual net mass balance over the accumulation area of Finsterwalderbreen, Spitsbergen, Svalbard (by detection of the 1962–63 radioactive peak from the 1961–62 atmospheric nuclear tests), we collected 14 ice cores, at elevations of 445–730 m, in the springs of 1994 and 1995. The corresponding samples were melted and filtered for laboratory gamma spectrometry. In the accumulation area, the 1962–63 radioactive layer is found well below the surface. The mean annual accumulation is not invariably related to altitude. The EL, averaged to 545 in

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14

Agrawal, Vaibhav, Sandra K. Althouse, Rafat Abonour, et al. "High-dose chemotherapy (HDCT) and peripheral-blood stem cell transplant (PBSCT) in patients age 40 or older with relapsed metastatic germ-cell tumors (mGCT)." Journal of Clinical Oncology 38, no. 15_suppl (2020): e17054-e17054. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e17054.

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e17054 Background: HDCT plus PBSCT is effective salvage therapy for relapsed mGCT but has potential toxicity. Historically, age ≥ 40 years has been associated with greater toxicity and worse outcomes. Methods: 445 consecutive pts with relapsed mGCT were treated with HDCT and PBSCT with tandem cycles at Indiana University from between 2004-2017 per our institutional regimen ( N Engl J Med 2007; 357:340-8). Kaplan-Meier methods and log-rank tests were used for progression free survival (PFS) analysis. Results: 329 pts were age < 40 while 116 pts were age≥40 and HDCT was being used as 2nd line

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15

MOSUPYE, FRANCINA M., and ALEXANDER von HOLY. "Microbiological Quality and Safety of Ready-to-Eat Street-Vended Foods in Johannesburg, South Africa." Journal of Food Protection 62, no. 11 (1999): 1278–84. http://dx.doi.org/10.4315/0362-028x-62.11.1278.

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Fifty-one ready-to-eat street foods, 18 dishwater, and 18 surface swab samples were collected from six vendors in Johannesburg, South Africa. Food temperatures were recorded at the time of sampling. Standard methods were used to determine aerobic plate counts (APCs), spore counts (SCs), and Enterobacteriaceae counts (ECs) for food samples as well as coliform counts (CCs) for water and swab samples. In addition, Petrifilm Escherichia coli count (PC) plates were used for the enumeration of coliforms in food, water, and swab samples. The presence of selected foodborne pathogens in the food sample

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16

Hernández-Cruz, B., M. J. Miranda García, J. Barrera, et al. "AB1030 PATIENT CARE AT THE FRACTURE LIAISON SERVICE REDUCE THE GAP IN THE TREATMENT OF OSTEOPOROSIS BETWEEN MEN AND WOMEN." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1638–39. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4150.

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BackgroundOsteoporosis (OP) between men and women is different,and the way it is treated also differs. In men, the gap in clinical care, especially diagnosis and treatment, is worse.ObjectivesTo analyze the differences in the clinical characteristics of OP (demographics, comorbidities, diagnosis, and treatment) in an gold star Fracture Liaison Service (FLS).MethodsDesign: Observational, prospective, analytical study of usual clinical practice. All patients treated from an FLS from May 2018 to August 2021 were prospectively included. Of each patient, 160 clinical variables were introduced in a

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17

Khozin, Anisa Unuf, and Yana Indawati. "Analisis Disparitas Penjatuhan Pidana Rehabilitasi Bagi Pelaku Penyalahgunaan Narkotika Untuk Diri Sendiri." Hukum dan Masyarakat Madani 14, no. 2 (2024): 344–58. https://doi.org/10.26623/humani.v14i2.9161.

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Penelitian ini bertujuan untuk menganalisis perbedaan penjatuhan pidana rehabilitasi terhadap Terdakwa dalam Putusan Nomor 340/Pid.Sus/2020/PN.Sda dan Putusan Nomor 14/Pid.S/2020/PN.Sby. Jenis penelitian yang digunakan ialah yuridis normatif dengan menggunakan pendekatan perundang-undangan, pendekatan kasus, pendekatan konseptual. Bahan hukum bersumber dari bahan hukum primer, bahan hukum sekunder, dan bahan nonhukum. Metode pengumpulan data dilakukan dengan menganalisis Putusan Nomor 340/Pid.Sus/2020/PN.Sda dan Putusan Nomor 14/Pid.S/2020/PN.Sby dan studi kepustakaan. Hasil penelitian menunju

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18

Nagler, Arnon. "SP-043 HAPLOIDENTICAL STEM CELL TRANSPLANTATION." Leukemia Research 38 (October 2014): S19. http://dx.doi.org/10.1016/s0145-2126(14)70040-2.

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19

Chaverri, Carlos, and José F. Cicció. "Essential oils of Baccharis trinervis (Asteraceae) from Costa Rica." Revista de Biología Tropical 65, no. 4 (2017): 1307. http://dx.doi.org/10.15517/rbt.v65i4.27845.

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Baccharis is an Asteraceae genus of flowering plants, which has about 340 to 400 species, ranging from the Southern United States to the Southern extreme of Argentina and Chile through Central America and the Caribbean regions. The species Baccharis trinervis is a native shrub from Mexico, Central America and throughout South America. In Costa Rica, this species is commonly known as alcotán and the fresh leaves are used as a poultice on wounds and ulcers. The objective of the present research was to characterize the chemical composition of seven hydrodistilled essential oils of diverse morphol

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20

Pascal, Laurent, Odile Beyne Rauzy, Sabine Brechignac, et al. "Highly Transfused MDS Patients Often Have Cardiac Iron Overload, as Shown by MRI Assessment." Blood 116, no. 21 (2010): 2906. http://dx.doi.org/10.1182/blood.v116.21.2906.2906.

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Abstract Abstract 2906 Background: Cardiac complications of transfusional iron overload are well documented in various inherited anemias. In regularly transfused MDS, the deleterious role of iron overload on cardiac disease is more disputed, due in particular to frequent concomitant causes of cardiac failure. Cardiac MRI T2* allows accurate and specific measurement of iron content. Methods: We prospectively evaluated in 4 centers of the GFM by standardized and transferable MRI methods both cardiac T2* according to Anderson (Eur Heart J. 2001Dec;22(23):2171-9) and liver iron content (LIC) accor

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21

Falchook, Gerald Steven, Meredith McKean, William Kevin Kelly, et al. "Phase 1 clinical trial of AMG 340, a prostate-specific membrane antigen (PSMA)-targeted T-cell engager with a novel low-affinity CD3 binding domain designed to mitigate toxicity for the treatment of metastatic castration-resistant prostate cancer (mCRPC)." Journal of Clinical Oncology 42, no. 16_suppl (2024): e14587-e14587. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e14587.

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e14587 Background: PSMA, a transmembrane protein highly expressed on the surface of prostate cancer cells, is a validated target in prostate cancer; however, achieving a favorable therapeutic index has been challenging for PSMA-directed T-cell engagers (TCE’s). AMG 340, a PSMA-targeted TCE with a novel low-affinity CD3 binding domain specifically engineered to mitigate cytokine release syndrome (CRS) toxicity and maintain efficacy was investigated in a phase 1, open-label, dose-escalation study (NCT04740034). Methods: Patients (pts) with mCRPC who had received ≥2 prior lines of therapy were tr

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22

Attook, Saja Makki, and Emad Bakr Al-Zangana. "Special Arcs in PG(3,13)." Al-Mustansiriyah Journal of Science 33, no. 4 (2022): 86–91. http://dx.doi.org/10.23851/mjs.v33i4.1197.

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In this paper, we constructed new arcs in the three-dimensional projective space over GF(13) of degrees 2, 3, 4, 5, 6, 7, 10, 11, 14, 15, 18, 19, 23, 28, 30, 47, 55, 98 and sizes 2, 4, 5, 7, 10, 14, 17, 20, 28, 34, 35, 68, 70, 85, 119, 140, 170, 238, 340, 476, 595, 1190. These arcs are classified to complete and incomplete arcs. Also, the incomplete arcs are extended to complete arcs.

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23

Bell, R. A., B. E. Brown, M. Duarte, H. E. Howard-Lock, and C. J. L. Lock. "Structural and vibrational studies of 1,1,3,3-tetracyanopropane and 2,2,4,4,6-pentacyanocyclohexenamine." Canadian Journal of Chemistry 65, no. 2 (1987): 261–70. http://dx.doi.org/10.1139/v87-043.

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1,1,3,3-Tetracyanopropane, 1, was prepared in low yields by a literature method with 2,2,4,4,6-pentacyanocyclohexenamine, 2, as a major by-product. The products were examined by X-ray crystallography. 1 has an orthorhombic space group, Pbcn (No. 60) with cell dimensions, a = 7.158(2), b = 10.510(3), c = 9.733(2) Å and has four formula units in the unit cell. 2 has a monoclinic cell, P21/c (No. 14) with cell dimensions a = 14.368(3), b = 6.626(1), c = 12.300(2) Å, β = 115.60(1)° and has 4 formula units in the unit cell. Data were collected with use of MoKα radiation and a Nicolet P3 diffractome

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24

Kadia, Tapan, Jorge E. Cortes, Elias J. Jabbour, et al. "Phase II Study of Cladribine, Idarubicin, and Cytarabine (araC) in Patients with Acute Myeloid Leukemia (AML)." Blood 126, no. 23 (2015): 2541. http://dx.doi.org/10.1182/blood.v126.23.2541.2541.

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Abstract Background Slow progress has been made in improving induction therapy for patients (pts) with AML. Nucleoside analogues such as cladribine can increase the efficacy of araC by modulating deoxycytidine kinase. Indeed, the addition of cladribine to standard 7+3 chemotherapy has been shown to improve survival in pts with AML (Holowiecki JCO 2012). Additionally, higher doses of araC during induction may have a role in improving outcomes for younger pts (Burnett JCO 2013, Willemze JCO 2013). We conducted a trial to study the efficacy of cladribine combined with higher-dose araC during indu

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25

Weragoda, Geethika K., Anushree Das, Sujan K. Sarkar, et al. "Singlet Photoreactivity of 3-Methyl-2-phenyl-2H-azirine." Australian Journal of Chemistry 70, no. 4 (2017): 413. http://dx.doi.org/10.1071/ch16604.

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Irradiation of 3-methyl-2-phenyl-2H-azirine (1) at 254 nm in argon matrices results in ylide 6. Similarly, laser flash photolysis (λ = 266 nm) of azirine 1 in acetonitrile yields ylide 6, which has a transient absorption with λmax at ~340 nm and a lifetime of 14 μs. Density functional theory calculations were preformed to support the characterisation of ylide 6 in solution and argon matrices. Irradiation of azirine 1 above 300 nm has previously been reported (J. Org. Chem. 2014, 79, 653) to yield triplet vinylnitrene in solution and ketenimine in cryogenic argon matrices. Thus, the photochemis

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26

He, Xin, Kyriakie Sarafoglou, Patricia Y. Fechner, et al. "Changes in Adrenal and Gonadal Androgens After 14-Day Treatment With CRF1 Receptor Antagonist, Crinecerfont (NBI-74788), in Men With Classic 21-Hydroxylase Deficiency." Journal of the Endocrine Society 5, Supplement_1 (2021): A78. http://dx.doi.org/10.1210/jendso/bvab048.157.

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Abstract Background: Congenital adrenal hyperplasia due to classic 21-hydroxylase deficiency (21OHD) causes cortisol insufficiency and androgen excess. A phase 2 trial of crinecerfont, a CRF1 receptor antagonist, in 18 adults with 21OHD showed prominent decreases in ACTH, 17-hydroxyprogesterone, and androstenedione (A4), and in women, testosterone (T), after 14 days of treatment. In men with 21OHD, T derives from both adrenals and testes; in poor disease control, A4/T ratio is elevated due to disproportionately increased adrenal A4 production and decreased testicular T production. We sought to

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27

Najar, H., E. Palsson, and M. Landén. "P.2.d.043 A naturalistic study of antipsychotic-induced weight gain in bipolar disorder." European Neuropsychopharmacology 24 (October 2014): S438—S439. http://dx.doi.org/10.1016/s0924-977x(14)70701-1.

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28

Osei, J. A., J. N. Peña-Sánchez, S. A. Fowler, N. Muhajarine, G. Kaplan, and L. M. Lix. "P771 Increasing prevalence and direct health care cost of inflammatory bowel disease: A population-based evidence from a western Canadian province." Journal of Crohn's and Colitis 14, Supplement_1 (2020): S611—S612. http://dx.doi.org/10.1093/ecco-jcc/jjz203.899.

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Abstract Background More than 0.3% of the populations in Europe, North America, and Oceania live with inflammatory bowel disease (IBD). Canada has increasing prevalence trends of IBD with 1% of Canadians estimated to have IBD by 2030. Evidence about IBD prevalence and health care costs over time can contribute to health resources allocation and health care planning. Our study aimed to 1) estimate the prevalence and direct health care costs of IBD in the province of Saskatchewan (SK), Canada, and 2) test if trends in the prevalence and direct health care costs of IBD increased over two decades.

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JALBOUT, A. F., A. DE LEON, L. ADAMOWICZ, et al. "THEORETICAL, EMPIRICAL AND EXPERIMENTAL ELECTRON AFFINITIES OF SF6: SOLVING THE DENSITY FUNCTIONAL ENIGMA." Journal of Theoretical and Computational Chemistry 06, no. 04 (2007): 747–59. http://dx.doi.org/10.1142/s0219633607003465.

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We postulate that the adiabatic electron affinity of SF6 is 2.40(10) eV, obtained from the photodetachment onset, 3.2(1) eV and a rearrangement energy of 0.8(1) eV. This eliminates the perceived "SF6 density functional enigma". All of the experimental electron affinities are evaluated and 14 significantly different values selected to construct empirical anionic Morse potentials. These values are (in eV): 2.40(10) 2.20(10), 2.00(10), 1.80(10), 1.60(10), 1.20(10), 1.07(7), 0.93(10), 0.80(10), 0.63(10), 0.43(10), 0.30(10), 0.10(10), and 0.0(2). Comparisons are made to theoretical calculations and

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Hasrouni, Edy, Valeria Visconte, Ali Tabarroki, et al. "Pathway Analysis of Molecular Mutations Can Modify Morphologic, Cytogenetic and Prognostic Risk Stratification Schemes in Myelodysplastic Syndromes (MDS), Myelodysplastic Syndromes/Myeloproliferative Neoplasms (MDS/MPN), and Secondary Acute Myeloid Leukemia (AML)." Blood 120, no. 21 (2012): 3791. http://dx.doi.org/10.1182/blood.v120.21.3791.3791.

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Abstract Abstract 3791 Molecular mutations of genes important in MDS pathogenesis have been identified using next generation sequencing technologies. These mutations have variable effects on prognosis: results from individual studies are conflicting, and the impact of combining mutations based on pathogenetic pathways has not been explored. Furthermore, most studies do not take into account the types of therapies received by patients (pts). We hypothesized that analyses of mutations incorporating pathways would yield more meaningful results, especially if studied in the context of therapies. W

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31

Gross, R., A. Goral, E. Grossman, and K. Muhsen. "P.2.b.043 Hypertension, depressive symptoms, and risk behaviors: results from a national health survey." European Neuropsychopharmacology 24 (October 2014): S404—S405. http://dx.doi.org/10.1016/s0924-977x(14)70644-3.

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32

Bowmaker, Graham A., Effendy, Eban N. de Silva та Allan H. White. "Lewis-Base Adducts of Group 11 Metal(I) Compounds. LXXII Synthesis, Spectroscopy and Structural Systematics of Some 1 : 2 Binuclear Complexes of Silver(I) Halides with Triphenylstibine, [(Ph3Sb)2Ag(μ-X)2Ag(SbPh3)2], X = Cl, Br, I". Australian Journal of Chemistry 50, № 6 (1997): 641. http://dx.doi.org/10.1071/c96038.

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Syntheses and room-temperature single-crystal X-ray structural characterization of binuclear 1 : 2 adducts formed between silver(I) halides, AgX (X = Cl, Br, I), and triphenylstibine, SbPh3, are described. The three complexes are isomorphous, being triclinic, P-1, a ≈ 18·5, b ≈ 14·6, c ≈ 14·5 Å, α ≈ 62·5, β ≈ 74, γ ≈ 77°, Z = 2 centrosymmetric dimers. Conventional R on F were 0·043, 0·038 and 0·046 for 4984, 8479 and 4166 independent, ‘observed’ (I > 3σ(I)) reflections respectively. In [(Ph3b)2Ag(µ-X)2Ag(SbPh3)2], Ag–Sb range between 2·702(1) and 2·744(2) Å, lengthening slightly from chlori

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33

Pinto, Rafael Henrique Faia, Caio Matheus Comar Cambui, Anderson Rogério Faia Pinto, and Bruna Cristine Scarduelli Pacheco. "Aplicações do Custeio ABC combinado ao Método de Apoio a Decisão Multicritério AHP: uma revisão da literatura." Brazilian Journal of Business 4, no. 4 (2022): 2205–14. http://dx.doi.org/10.34140/bjbv4n4-043.

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A gestão de custos é hoje fator eminente á competitividade das empresas. Porém, há uma lacuna entre os sistemas de produção e o melhor modelo de custeio para a tomada de decisão em níveis gerenciais. Dentre os melhores métodos de custeio está Activity Based Costing (ABC). A principal dificuldade do abc está no estabelecimento dos direcionadores de custos. Diante desta questão alguns pesquisadores passaram a aliar o Analytic Hierarchy Process (AHP) em conjunto ao Activity Based Costing (ABC). Logo, este artigo tem como objetivo realizar uma revisão de literatura em torno das pesquisas que fizer

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34

Wu, Shao-Chun, Cheng-Shyuan Rau, Johnson Chia-Shen Yang, et al. "Identification of Circulating miRNAs in a Mouse Model of Nerve Allograft Transplantation under FK506 Immunosuppression by Illumina Small RNA Deep Sequencing." Disease Markers 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/863192.

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Background. This study aimed to establish the expression profile of circulating microRNAs (miRNAs) during nerve allotransplantation in the presence and absence of FK506 immunosuppression.Methods. A 1 cm BALB/c donor sciatic nerve graft was transplanted into the sciatic nerve gaps created in recipient C57BL/6 mice with or without daily FK506 immunosuppression [1 mg/(kg·d)]. At 3, 7, and 14 d after nerve allotransplantation, serum samples were collected for miRNA expression analysis by Illumina small RNA deep sequencing.Results. Sequence analysis showed that the dominant size of circulating smal

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35

M., Gangadharappa, Raveendra Reddy P., Krishna Reddy V., and Sreenivasulu Reddy T. "Direct spectrophotometric determination of gold(III) using 2-aminoacetophenone isonicotinoyl hydrazone (2-AAINH)." Journal of India Chemical Society Vol 81, Jun 2004 (2004): 525–27. https://doi.org/10.5281/zenodo.5833537.

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Department of Chemistry, Sri Krishnadevaraya University, Anantapur-515 003, India <em>Fa</em>x : 91-8554-29043 <em>Manuscript received 20 May 2003, revised 13 November 2003, accepted 14 January 2004</em> A simple, highly sensitive and specific spectrophotometric method has been developed for the determination of gold(III) in aqueous dimethylformamide (DMF). The metal ion reacts with 2-aminoacetophenone isonicotinoyl hydrazone (2-AAINH) forming a reddish brown complex in the pH range 3.0-6.0. The complex shows maximum absorption at 440 nm. Beer's law is obeyed in the range 0.400-5.00 )&micr

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36

Salman, Sam, Daryl Bendel, Toong C. Lee, David Templeton, and Timothy M. E. Davis. "Pharmacokinetics of a Novel Sublingual Spray Formulation of the Antimalarial Drug Artemether in Healthy Adults." Antimicrobial Agents and Chemotherapy 59, no. 6 (2015): 3197–207. http://dx.doi.org/10.1128/aac.05013-14.

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ABSTRACTThe pharmacokinetics of sublingual artemether (ArTiMist) was investigated in two open-label studies. In study 1, 16 healthy males were randomized to each of four single-dose treatments administered in random order: (i) 15.0 mg of sublingual artemether (5 × 3.0 actuations), (ii) 30.0 mg of sublingual artemether (10 × 3.0 mg), (iii) 30.0 mg of sublingual artemether (5 × 6.0 mg), and (iv) 30.0 mg of artemether in tablet form. In study 2, 16 healthy males were randomized to eight 30.0-mg doses of sublingual artemether given over 5 days as either 10 3.0-mg or 5 6.0-mg actuations. Frequent b

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37

C. Essah, S. Y., and N. C. Stoskopf. "Mixture performance of phenotypically contrasting barley cultivars." Canadian Journal of Plant Science 82, no. 1 (2002): 1–6. http://dx.doi.org/10.4141/p01-043.

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There is lack of information on the yield and yield component performance of same-row and alternate-row mixtures (SRM and ARM) of widely contrasting barley (Hordeum vulgare L.) phenotypes. Therefore, four phenotypically contrasting spring barley cultivars, each selected to represent a unique combination of spike type (two-row or six-row), height (short or tall) and days to maturity (early or late) were used in 1991 and 1992 in field experiments at the Elora Research Station in Ontario, Canada, with the objective of determining whether a yield and/or yield-component advantage could be associate

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38

MAURYA, MANISH KUMAR, H. K. SINGH, S. K. SINGH, and DINESH SINGH. "Management of black rot disease of rapeseed (Brassica napus)-Indian mustard (Brassica juncea) caused by Xanthomonas campestris pv. campestris." Indian Journal of Agricultural Sciences 92, no. 8 (2022): 1033–37. http://dx.doi.org/10.56093/ijas.v92i8.108616.

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Out of 340 genotypes/varieties screened against black rot disease in rapeseed-Indian mustard under field conditions, 15 genotypes found resistant, viz. RTM 1624, RTM 1626, TM EPAU, DRMRAB-7-116, NPJ-177, LES-55, DRMRIJ 16-1, RH 1514, BASANTI, NDRS 1-2, TMR 14-1, TMR- 14-4, TMR 14-5, TMR 14-3, T 27, can be utilized as a donor for the development of black rot disease resistant varieties in crucifer crops. All genotypes of Eruca sativa were found resistant against black rot disease. Under in vitro conditions, streptocycline @200 ppm had maximum inhibition zone 3.8 cm diameter with 73.48% inhibiti

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39

Stutte, G. W., and G. C. Martin. "Effect of Light Intensity and Carbohydrate Reserves on Flowering in Olive." Journal of the American Society for Horticultural Science 111, no. 1 (1986): 27–31. http://dx.doi.org/10.21273/jashs.111.1.27.

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Abstract Experiments were designed to alter the carbohydrate status of olive (Olea europaea L.) leaves during the presumed flower induction period. Bearing and nonbearing ‘Oblonga’ olive trees were exposed to either 850 μmol s-1n-2 PAR for 14 hr daily in a 1000 ppm CO2-enriched atmosphere, 150 μmol s-1m-2 PAR for 14 hr daily in 340 ppm CO2, or maintained in a lathhouse at ambient winter conditions of about 350 μmol s-1m-2 PAR and daily temperature fluctuations from 5° to 20°C. The trees exposed to 850 μmol s-1m-2 had 3 to 5 times the starch concentrations of either the 150 μmol s-1m-2 PAR or l

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40

Amar, Puti Khairunnajwa, Mansyurdin Mansyurdin, Nova Syafni, Ersa Nur Syafia, and Muhammad Idris. "Monitoring Ekspresi Gen <i>Chalcone Synthase</i> dan Respon Pertumbuhan Lobak Singgalang (<i>Brassica oleracea</i> L.) Akibat Paparan Ultraviolet-B Ekstrem." Vegetalika 14, no. 2 (2025): 124. https://doi.org/10.22146/veg.103190.

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Singgalang cabbage (Brassica oleracea L.) is a local vegetable native to West Sumatra, cultivated in highlands around Mount Singgalang, Tanah Datar. Vegetables from Brassica genus are recognized for their high nutritional value and potential as functional foods. Key secondary metabolites in Brassica species, i.e., phenolic compounds and their derivatives, play a crucial role in antioxidant activity and are essential in promoting health. Light exposure, particularly ultraviolet-B (UV-B, 280-315 nm), can enhance biosynthesis of these compounds. UV-B intensity affects various process in plants in

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41

Blas, Andrea L., Qingyi Yu, Cuixia Chen, et al. "Enrichment of a papaya high-density genetic map with AFLP markers." Genome 52, no. 8 (2009): 716–25. http://dx.doi.org/10.1139/g09-043.

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A high-density genetic linkage map of papaya, previously developed using an F2 mapping population derived from the intraspecific cross AU9 × SunUp, was enriched with AFLP markers. The comprehensive genetic map presented here spans 945.2 cM and covers 9 major and 5 minor linkage groups containing 712 SSR, 277 AFLP, and 1 morphological markers. The average marker density for the 9 major linkage groups is 0.9 cM between adjacent markers, and the total number of gaps >5 cM was reduced from 48 to 27 in the current map. AFLPs generated by EcoRI/MseI primer combinations were distributed throughout

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42

Burnier, Gerald, and Pierre Vogel. "Synthesis and Tandem Diels-Alder Reactivity of 1,3 Dimethoxy-5,6,7,8-tetramethylidene-bicyclo[2.2.2]oct-2-ene." CHIMIA 41, no. 12 (1987): 429. https://doi.org/10.2533/chimia.1987.429.

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The synthesis of 1,3-dimethoxy-5,6,7,8-tetramethylidenebicyclo[2.2.2]oct-2-ene (13) is presented. 13 added one equivalent of ethylenetetracarbonitrile (TCNE) to give the corresponding monoadduct 18 (k1II = 204 × 10-3 dm3mol-1s-1 at 25 °C, ΔH1‡ = 10.7 ± 0.5 kcal mol-1, ΔS1‡= −26 ± 2 cal K-1mol-1). 18 added another equivalent of TCNE and afforded the bisadduct 19 (k2II = 0.6 × 10-1 dm3mol-1s-1 at 25 °C, ΔH2‡ = 14 ± 1 kcal mol-1, ΔS2‡= = −26 ± 4 cal K-1mol-1). The tandem Diels-Alder reactivity of 13 given by the rate constant ratio k1II/k2II = 340 (at 25 °C) is compared with that reported for 2,3

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43

Vij, Ravi, Michael Savona, David S. Siegel, et al. "Clinical Profile of Single-Agent Oprozomib in Patients (Pts) with Multiple Myeloma (MM): Updated Results from a Multicenter, Open-Label, Dose Escalation Phase 1b/2 Study." Blood 124, no. 21 (2014): 34. http://dx.doi.org/10.1182/blood.v124.21.34.34.

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Abstract Background: Oprozomib (OPZ) is an oral epoxyketone proteasome inhibitor that selectively and irreversibly binds to its target. Preliminary findings of OPZ in pts with hematologic malignancies (HM) have been reported previously (Savona, ASH 2012, 203; Kaufman, EHA 2013, P223; Ghobrial, ASH 2013, 3184). Updated safety and efficacy results from the subset of pts with MM enrolled in this ongoing phase 1b/2 study in pts with HM are presented. Methods: This open-label, phase 1b/2 study (NCT01416428) is enrolling adult pts with HM who have relapsed after receiving ≥1 line of therapy. The pri

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Marques, Ilza Lazarini, Suely Prieto de Barros Almeida Peres, Heloisa Bettiol, Marco Antonio Barbieri, Mauro Andrea, and Luiz de Souza. "Growth of Children with Isolated Robin Sequence Treated by Nasopharyngeal Intubation: Importance of a Hypercaloric Diet." Cleft Palate-Craniofacial Journal 41, no. 1 (2004): 53–58. http://dx.doi.org/10.1597/02-043.

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Objective To compare the growth curves (weight and length) of two groups of infants with isolated Robin sequence (RS) treated with nasopharyngeal intubation (NPI), one group receiving a hypercaloric diet and the other receiving a normal diet for age, and compare the growth rates and duration of NPI between the two groups. Design Prospective longitudinal study. Setting Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, Brazil, 1998 to 2000. Patients Twenty-three children with isolated RS treated by prolonged NPI. Interventions Nine children received a milk fo

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45

Medeiros, Thales M., João B. Ribeiro-Alvares, Carolina G. Fritsch, et al. "Effect of Weekly Training Frequency With the Nordic Hamstring Exercise on Muscle-Strain Risk Factors in Football Players: A Randomized Trial." International Journal of Sports Physiology and Performance 15, no. 7 (2020): 1026–33. http://dx.doi.org/10.1123/ijspp.2018-0780.

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Purpose: To examine the differences between performing Nordic hamstring exercises once or twice a week on hamstring eccentric strength and other muscle-strain risk factors in high-level football players. Methods: In this randomized trial, 32 football players (18–23 y old) completed an 8-week Nordic hamstring exercise training program in 1 of 2 experimental groups: group 1 (once a week; n = 15) and group 2 (twice a week; n = 17). Knee-flexor/extensor peak torques and biceps femoris long-head muscle architecture were assessed through isokinetic dynamometry and ultrasonography, respectively, befo

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46

Lima, Hawlinston R. C., Haerishton R. Cavalcante-Lima, Pedro L. Cedraz-Mercez, et al. "Brain serotonin depletion enhances the sodium appetite induced by sodium depletion or beta-adrenergic stimulation." Anais da Academia Brasileira de Ciências 76, no. 1 (2004): 85–92. http://dx.doi.org/10.1590/s0001-37652004000100008.

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We investigate the influence of brain serotonin depletion on the sodium appetite. Rats depleted of serotonin through the systemic administration of p-chlorophenylalanine (300 mg/kg, ip, for 2 days) showed an intense natriorexigenic response induced by sodium depletion (furosemide, 20 mg/kg, sc, 24 h before water and 1.8% NaCl presentation). Intake of 1.8% NaCl was always higher than that observed for the control group (12.9 ± 1.4 and 21.4 ± 3.0 mL vs 5.7 ± 1.2 and 12.7 ± 1.6 mL, 30 and 300 min after water and saline presentation). After 24 h, the natriorexigenic response continued to be signif

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47

Hu, Mimi I., Rossella Elisei, Marek Dedecjus, et al. "Safety and efficacy of two starting doses of vandetanib in advanced medullary thyroid cancer." Endocrine-Related Cancer 26, no. 2 (2019): 241–50. http://dx.doi.org/10.1530/erc-18-0258.

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Vandetanib is an oral tyrosine kinase inhibitor approved for treatment of advanced symptomatic or progressive medullary thyroid cancer (MTC). The current study (Nbib1496313) evaluated the benefit–risk of two starting doses of vandetanib in patients with symptomatic or progressive MTC. Patients were randomized 1:1 to receive vandetanib 150 or 300 mg daily and followed for a maximum of 14 months (Part A), with the option to then enter an open-label phase (Part B) investigating vandetanib 100, 150, 200 and 300 mg daily doses. Efficacy was assessed in Part A, and safety and tolerability during Par

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Achilles, Sharon L., Clifton W. Kelly, Craig J. Hoesley, et al. "Phase 1 randomized trials to assess safety, pharmacokinetics, and vaginal bleeding associated with use of extended duration dapivirine and levonorgestrel vaginal rings." PLOS ONE 19, no. 6 (2024): e0304552. http://dx.doi.org/10.1371/journal.pone.0304552.

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Background Vaginal rings formulated to deliver two drugs simultaneously have potential as user-controlled, long-acting methods for dual prevention of HIV and pregnancy. Methods Two phase 1 randomized trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019) respectively enrolled 24 and 25 healthy, HIV-negative participants to evaluate safety, pharmacokinetics, and vaginal bleeding associated with use of a vaginal ring containing 200mg dapivirine (DPV) and 320mg levonorgestrel (LNG) designed for 90-day use. MTN-030/IPM 041 compared the DPV/LNG ring to a DPV-only ring (200mg) over 14 days of use. MTN-

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Miura, Toshihiro, Ko Furuta, Akiyo Yasuda, et al. "Antidiabetic Effect of Nitobegiku in KK-Ay Diabetic Mice." American Journal of Chinese Medicine 30, no. 01 (2002): 81–86. http://dx.doi.org/10.1142/s0192415x02000090.

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In the past, Nitobegiku (the herb of Tithonia diversifolia (Hemsl) A. Gray) has been used as a medicinal plant for diabetes. Antidiabetic effect of the water extract of Nitobegiku (NG) was investigated in KK-Ay-mice — one of the animal models of type 2 diabetes. NG (1500 mg/kg body weight) reduced the blood glucose of KK-Ay mice from 509 ± 22 mg/dl to 340 ± 14 mg/dl (p < 0.001) and also lowered the plasma insulin (p < 0.05) 7 hours after single oral administration. No change in blood glucose of NG-treated normal mice (ddY) was seen. These results support that NG improve glucose metabolis

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Trenberth, Kevin E., John T. Fasullo, Karina von Schuckmann, and Lijing Cheng. "Insights into Earth’s Energy Imbalance from Multiple Sources." Journal of Climate 29, no. 20 (2016): 7495–505. http://dx.doi.org/10.1175/jcli-d-16-0339.1.

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Abstract The current Earth’s energy imbalance (EEI) can best be estimated from changes in ocean heat content (OHC), complemented by top-of-atmosphere (TOA) radiation measurements and an assessment of the small non-ocean components. Sustained observations from the Argo array of autonomous profiling floats enable near-global estimates of OHC since 2005, which reveal considerable cancellation of variations in the upper 300 m. An analysis of the monthly contributions to EEI from non-ocean components (land and ice) using the Community Earth System Model (CESM) Large Ensemble reveals standard deviat

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