Добірка наукової літератури з теми "4003 Biomedical engineering"

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Статті в журналах з теми "4003 Biomedical engineering"

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Wang, Xinwei, Haijun Peng, Sheng Zhang, Biaosong Chen, and Wanxie Zhong. "A symplectic local pseudospectral method for solving nonlinear state-delayed optimal control problems with inequality constraints." International Journal of Robust and Nonlinear Control 28, no. 6 (December 7, 2017): 2097–120. http://dx.doi.org/10.1002/rnc.4003.

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Zheng, Lei, and Hui-Fei Cui. "Use of chitosan conduit combined with bone marrow mesenchymal stem cells for promoting peripheral nerve regeneration." Journal of Materials Science: Materials in Medicine 21, no. 5 (January 26, 2010): 1713–20. http://dx.doi.org/10.1007/s10856-010-4003-y.

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Díaz-Castillo, Carlos. "Transcriptome dynamics along axolotl regenerative development are consistent with an extensive reduction in gene expression heterogeneity in dedifferentiated cells." PeerJ 5 (November 6, 2017): e4004. http://dx.doi.org/10.7717/peerj.4004.

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Although in recent years the study of gene expression variation in the absence of genetic or environmental cues or gene expression heterogeneity has intensified considerably, many basic and applied biological fields still remain unaware of how useful the study of gene expression heterogeneity patterns might be for the characterization of biological systems and/or processes. Largely based on the modulator effect chromatin compaction has for gene expression heterogeneity and the extensive changes in chromatin compaction known to occur for specialized cells that are naturally or artificially induced to revert to less specialized states or dedifferentiate, I recently hypothesized that processes that concur with cell dedifferentiation would show an extensive reduction in gene expression heterogeneity. The confirmation of the existence of such trend could be of wide interest because of the biomedical and biotechnological relevance of cell dedifferentiation-based processes, i.e., regenerative development, cancer, human induced pluripotent stem cells, or plant somatic embryogenesis. Here, I report the first empirical evidence consistent with the existence of an extensive reduction in gene expression heterogeneity for processes that concur with cell dedifferentiation by analyzing transcriptome dynamics along forearm regenerative development inAmbystoma mexicanumor axolotl. Also, I briefly discuss on the utility of the study of gene expression heterogeneity dynamics might have for the characterization of cell dedifferentiation-based processes, and the engineering of tools that afforded better monitoring and modulating such processes. Finally, I reflect on how a transitional reduction in gene expression heterogeneity for dedifferentiated cells can promote a long-term increase in phenotypic heterogeneity following cell dedifferentiation with potential adverse effects for biomedical and biotechnological applications.
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Dimitrijevic, Milan R. "The conducting and processing capabilities of the human lumbar cord network and “spinal brain”." Biomedical Engineering / Biomedizinische Technik 58, s1-keynote (January 7, 2013): 1–4. http://dx.doi.org/10.1515/bmt-2013-4001.

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Keen, Imelda, Lynette Lambert, Traian V. Chirila, Stefan M. Paterson, and Andrew K. Whittaker. "Degradable Hydrogels for Tissue Engineering – Part I: Synthesis by RAFT Polymerization and Characterization of PHEMA Containing Enzymatically Degradable Crosslinks." Journal of Biomimetics, Biomaterials and Tissue Engineering 6 (September 2010): 67–85. http://dx.doi.org/10.4028/www.scientific.net/jbbte.6.67.

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A nonapeptide, which is sensitive to enzymatic digestion by collagenase, was modified by the covalent attachment of an acrylamido group at the terminal positions. The functionalized peptide was used as a crosslinking agent during polymerization of 2-hydroxyethyl methacrylate (HEMA). Reversible addition-fragmentation chain transfer (RAFT) method was used to obtain a polymer (PHEMA) with an average theoretical molecular weight of 4000 Da, containing enzymatically labile peptide crosslinks. The functionalized peptide was analyzed in detail by 1H and 13C nuclear magnetic resonance (NMR) spectrometry. The polymerization reaction was monitored by near infrared spectrometry, while the resulting polymer was analyzed by size exclusion chromatography and solid NMR spectrometry. The peptide-crosslinked PHEMA was subjected to an in-vitro degradation assay in the presence of collagenase. At the highest concentration of enzyme used in the study, a weight loss of 35% was recorded after 60 days of incubation in the collagenolytic medium. This suggests that crosslinking with enzymatically degradable peptides is a valid method for inducing biodegradability in polymers that otherwise are not degradable.
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Gurzhiev, A. N., S. N. Gurzhiev, M. G. Kirichenko, and A. V. Kostritskii. "Comparison of ProScan-2000 and ProMatrix-4000 Digital Fluorographs." Biomedical Engineering 39, no. 5 (September 2005): 255–58. http://dx.doi.org/10.1007/s10527-006-0014-x.

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Ghosh, Avijit, Priyanka Upadhyay, Sushmita Sarker, Shaswati Das, Mousumi Bhattacharjee, Saurav Bhattacharya, Manisha Ahir, et al. "Delivery of novel coumarin–dihydropyrimidinone conjugates through mixed polymeric nanoparticles to potentiate therapeutic efficacy against triple-negative breast cancer." Biomaterials Science 9, no. 16 (2021): 5665–90. http://dx.doi.org/10.1039/d1bm00424g.

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Coumarin–dihydropyrimidinone conjugates (CDHPs) and their poly(lactic-co-glycolic acid) (PLGA)-PEG4000 mixed copolymer nanoparticles as excellent chemotherapeutic nanomedicine to control TNBC.
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Acharya, Chitrangada, Anindya Dutta, and S. C. Kundu. "Surface Treatment of Pure and PEG-4000 Blended Fibroin Films and their Characterizations as Matrices for in vitro Fibroblast Culture." Journal of Biomaterials Applications 23, no. 6 (September 18, 2008): 497–517. http://dx.doi.org/10.1177/0885328208094261.

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Kabeerdass, Nivedhitha, Karthikeyan Murugesan, Natarajan Arumugam, Abdulrahman I. Almansour, Raju Suresh Kumar, Sinouvassane Djearamane, Ashok Kumar Kumaravel, et al. "Biomedical and Textile Applications of Alternanthera sessilis Leaf Extract Mediated Synthesis of Colloidal Silver Nanoparticle." Nanomaterials 12, no. 16 (August 12, 2022): 2759. http://dx.doi.org/10.3390/nano12162759.

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The aqueous extract of Alternanthera sessilis (As) acts as the precursors for the quick reduction of silver ions, which leads to the formation of silver nanoparticles. In the agar, well diffusion method of the Klebsiella pneumoniae shows the minimal inhibitory concentration of 12 mm against A. sessilis mediated silver nanoparticles (As-AgNPs) at 60 µg/mL concentration. Fabric treated with novel AS-AgNPs is tested against the K. pneumoniae and shows an inhibitory action of 12 mm with mixed cotton that determines the antimicrobial efficacy of the fabrics. Uv- visible spectrophotometer was performed, showing a surface plasmon resonance peak at 450 nm cm−1. FTIR shows the vibration and the infrared radiation at a specific wavelength of 500–4000 cm−1. The HR-TEM analysis showed the presence of black-white crystalline, spherical-shaped As-AgNPs embedded on the fabrics range of 15 nm–40 nm. In the scanning electron microscope, the presence of small ball-shaped As-AgNPs embedded on the fabrics at a voltage of 30 KV was found with a magnification of 578X. EDAX was performed in which the nanoparticles show a peak of 2.6–3.9 KeV, and it also reveals the presence of the composition, distribution, and elemental mapping of the nanoparticles. The cytotoxic activity of synthesized nanosilver was carried out against L929 cell lines, which show cell viability at a concentration of 2.5 µg mL−1. Cell proliferation assay shows no cytotoxicity against L929 cell lines for 24 h. In this study, the green synthesis of silver nanoparticles from A. sessilis appears to be a cheap, eco-friendly, and alternative approach for curing infectious ulcers on the floor of the stratum corneum. Nanotechnology conjoined with herbal therapeutics provides a promising solution for wound management.
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Nezaria, Jeremy Y., Christopher Sheils, Emilia Jahangir, Vincent Roy, and Sonya Bhavsar. "BIO28: Learnings from the Impella 5.5 with SmartAssist Ceramic Bearing System after 4000 Clinical Implants." ASAIO Journal 68, Supplement 2 (June 2022): 24. http://dx.doi.org/10.1097/01.mat.0000840848.60419.3b.

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Дисертації з теми "4003 Biomedical engineering"

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Kian, Azadeh. "An EMG-driven neuromusculoskeletal modelling framework for evaluation of shoulder muscle and joint function." Thesis, 2020. https://vuir.vu.edu.au/42684/.

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Книги з теми "4003 Biomedical engineering"

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United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Health and the Environment. National Institutes of Health issues: Hearings before the Subcommittee on Health and the Environment of the Committee on Energy and Commerce, House of Representatives, One Hundredth Congress, second session, February 22, 1988--National Biotechnology Information Act of 1987 (H.R. 393); March 4, 1988--Reauthorization of NIH (H.R. 3361 and H.R. 4013). Washington: U.S. G.P.O., 1988.

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Частини книг з теми "4003 Biomedical engineering"

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Lascano, Sheila, and Danilo Estay. "Biomedical Devices: Materials, Fabrication and Control." In Intelligent Systems, Control and Automation: Science and Engineering, 195–219. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-319-40003-7_9.

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Тези доповідей конференцій з теми "4003 Biomedical engineering"

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Cheng, Bo, Ping Lu, and Kevin Chou. "Thermomechanical Investigation of Overhang Fabrications in Electron Beam Additive Manufacturing." In ASME 2014 International Manufacturing Science and Engineering Conference collocated with the JSME 2014 International Conference on Materials and Processing and the 42nd North American Manufacturing Research Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/msec2014-4063.

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Electron beam additive manufacturing (EBAM) is one of powder-bed-fusion additive manufacturing processes that are capable of making full density metallic components. EBAM has a great potential in various high-value, small-batch productions in biomedical and aerospace industries. In EBAM, because a build part is immersed in the powder bed, ideally the process would not require support structures for overhang geometry. However, in practice, support structures are indeed needed for an overhang; without it, the overhang area will have defects such as warping, which is due to the complex thermomechanical process in EBAM. In this study, a thermomechanical finite element model has been developed to simulate temperature and stress fields when building a simple overhang in order to examine the root cause of overhang warping. It is found that the poor thermal conductivity of Ti-6Al-4V powder results in higher temperatures, also slower heat dissipation, in an overhang area, in EBAM builds. The retained higher temperatures in the area above the powder substrate result in higher residual stresses in an overhang area, and lower powder porosity may reduce the residual stresses associated with building an overhang.
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Chen, Shuo, Christopher E. Smith, Zhigang Xu, and Jagannathan Sankar. "Development of Biodegradable Mg-Zn-Ca Alloys for Biomedical Applications." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-40412.

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In the present study, Mg-8at.%Zn-1at.%Ca alloys were fabricated via T4 and T6 solid solution treatment technique for biomedical applications. The alloys were prepared at three different temperatures: 400 °C, 465 °C and 530°C followed by water or liquid nitrogen quenching. The microstructure of Mg-Zn-Ca alloys was characterized using X-ray diffraction (XRD) analysis, optical and electron microscopes, and energy dispersive spectroscopy, respectively. The examination of mechanical properties was conducted on micro hardness tester. The following differences can be concluded from the results: In water quenched samples, the following three phases were identified from XRD pattern: α -Mg matrix, binary Mg2Zn3 and ternary Ca2Mg6Zn3, the secondary phases are more agglomerated. At higher solution treatment temperature, the secondary phases became more dissolved to the Mg-matrix which creates better homogenized material. Higher treatment temperatures cause grains to grow and to a limited extent, samples quenched in liquid nitrogen have smaller grains than those quenched in water. The sample heat treated at the temperature of 465°C reaches a minimum hardness. While in liquid nitrogen quenched samples, the alloys consisted of four phases: α -Mg matrix, binary Mg2Zn3 and MgZn2 and ternary Ca2Mg6Zn3, the secondary phases are more distributed in a network form, at higher magnification, there are some secondary phases precipitated in rod/needle shape in the samples, the hardness of the samples decreases with the temperature increases.
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Lima, R. S., B. R. Marple, H. Lee, and S. A. Akbar. "Fabrication of Nanostructured TiO2 Fibers on TiO2 Coatings Produced from a Nanostructured Feedstock." In ITSC2006, edited by B. R. Marple, M. M. Hyland, Y. C. Lau, R. S. Lima, and J. Voyer. ASM International, 2006. http://dx.doi.org/10.31399/asm.cp.itsc2006p0787.

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Abstract Titania (TiO2) coatings were produced using the high velocity oxy-fuel (HVOF) technique on Ti-6Al-4V substrates. The titania feedstock powder exhibited nanostructured morphology, formed by the agglomeration of individual nanostructured titania particles (spray-drying) smaller than 100 nm. The resulting coatings were dense (porosity <1%) and exhibited rutile and anatase as phases with percentages of ~75% and ~25%, respectively. These coatings were heat-treated in a H2/N2 environment at 700oC for 8 h. During the heat-treatment, nanostructured titania fibers were formed on specific surface regions of the coatings. The nanofibers formed by this “chemical or reaction-based texturing” exhibited diameters of 50-400 nm and lengths in the order to 1-5 µm. It is thought that engineering these surfaces at nano and microscales may lead to interesting applications of titania coatings related to cell attachment/growth (for biomedical applications).
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Asmatulu, R., W. Khan, K. D. Nguyen, and M. B. Yildirim. "Synthesizing Magnetic Nanocomposite Fibers by Electrospinning Method." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-69111.

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Flexible magnetic nanocomposite fibers were produced by electrospinning method using a polymeric solution containing poly(acrylonitrile) and magnetite nanoparticles. Magnetic nanoparticles (∼10 nm) were prepared by a chemical co-precipitation of ferric and ferrous chloride salts in the presence of an ammonium hydroxide solution. The effect of magnetic particle concentrations (e.g., 0%, 1%, 5%, 10%, 20% and 30%) on nanocomposite fibers, distribution and morphology were studied using scanning electron microscopy (SEM). The experimental study indicated that the average diameters of the magnetic nanocomposite fibers were between 400 nm and 1.08 μm. The magnetic responds were also found to increase linearly with increasing percent loading of the magnetic nanoparticles. It is concluded that this study provides promising results for various applications, such as filtration and separation of micron and nanosize organic and inorganic particles, HF antenna fabrication and biomedical.
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Darmadi, I. Gede, and Budi Utomo Kukuh Widodo. "Analysis and optimization of a 400 MW coal-fired power plant under a proposed low-rank coal with flue gas recirculation mode." In THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5138270.

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Yeole, Shivraj, Nagabhushana Ramesh Nunna, Balu Naik Banoth, and Ramya Alluru. "Realization of Surface Morphology and Process Parameter Optimization in MicroEDM Hole Drilling of Maraging Steel 300 Alloy." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-53537.

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Анотація:
The Micro-Electrical Discharge Machining, popularly known as micro-EDM, is a nonconventional machining process mainly used for producing micro features like micro holes, micro gears, micro moulds etc. that are difficult to be obtained by conventional process. It can machine different types of conductive materials especially the ones which are difficult to cut and machine. Microholes have been drilled using micro-EDM process on various alloys like Ti-6Al-4V, Inconel 718 etc. using electrodes like Copper, Tungsten etc. The parts produced by micro-EDM are widely used in micro-electro-mechanical systems (MEMS), biomedical applications, automotive industry, and defence industry. Selection and use of correct process parameters is of paramount importance for achieving superior surface quality and higher machining rates while performing micro drilling. However, this process has been characterized by low tool wear rate, low machining rate and longer machining time as compared to other non-conventional processes. This paper aims at studying the influence of various process parameters while drilling micro holes on Maraging Steel 300 alloy using a brass electrode. Maraging Steel 300 alloy is widely used in aerospace, tooling and machinery applications. Brass was selected as the electrode material so as to know its influence in the microdrilling process as it is known for achieving high material removal rate along with high wear ratio. Machining parameters considered in this work were pulse on time, pulse off time, tool diameter and current. A total of 27 micro holes of 300 μm, 400 μm and 500 μm were drilled on Maraging Steel 300 alloy as per the orthogonal array design based Taguchi methodology. Experiments were carried out on Toolcraft V04056 micro-EDM machine. Dielectric used was distilled water. The output responses observed were material removal rate, tool wear rate and overcut. Analysis was carried out using signal to noise ratio analysis. Material removal rate, tool wear rate and overcut were found to be influenced mainly by pulse on time and current. In order to know and better understand the surface morphology of the micro-holes, SEM micro-graphs were obtained. Presence of spatters and re-deposited eroded material were observed in few of the drilled micro holes. The results were verified by performing confirmation experiment at the obtained optimum combination. The confirmation results were in close proximity to the predicted results.
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