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Статті в журналах з теми "528.2: 629.78"

Автор: Grafiati

Опубліковано: 30 травня 2022

Оновлено: 31 липня 2025

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1

Aydin, Serap, Nafiz Arica, Emrah Ergul, and Oğuz Tan. "Classification of Obsessive Compulsive Disorder by EEG Complexity and Hemispheric Dependency Measurements." International Journal of Neural Systems 25, no. 03 (2015): 1550010. http://dx.doi.org/10.1142/s0129065715500100.

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In the present study, both single channel electroencephalography (EEG) complexity and two channel interhemispheric dependency measurements have newly been examined for classification of patients with obsessive–compulsive disorder (OCD) and controls by using support vector machine classifiers. Three embedding entropy measurements (approximate entropy, sample entropy, permutation entropy (PermEn)) are used to estimate single channel EEG complexity for 19-channel eyes closed cortical measurements. Mean coherence and mutual information are examined to measure the level of interhemispheric dependen

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2

Bader-Zaar, Birgitta, Evguenia Davidova, Minja Bujaković, et al. "Book Reviews." Aspasia 16, no. 1 (2022): 203–43. http://dx.doi.org/10.3167/asp.2022.160114.

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Feminist Encounters: A Journal of Critical Studies in Culture and Politics 4, no. 2, “East European Feminisms, Part 1: The History of East European Feminisms,” eds. Maria Bucur and Krassimira Daskalova, 2020.Maria Bucur, The Nation’s Gratitude: World War I and Citizenship Rights in Interwar Romania, London: Routledge, 2022, vi–viii, 231 pp., $160.00 (hardback), $48.95 (ebook), ISBN: 978-0-367-74978-1.Sanja Ćopić and Zorana Antonijević, eds., Feminizam, aktivizam, politike: Proizvodnja znanja na poluperiferiji. Zbornik radova u čast Marine Blagojević Hughson (Feminism, activism, politics: Knowl

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3

Glicksman, Rachel, Di Maria Jiang, Philippe Bedard, et al. "Clinical outcomes of stage IIA/IIB seminoma treated with radiotherapy and chemotherapy: Should regional therapy be considered the preferred treatment approach?" Journal of Clinical Oncology 43, no. 5_suppl (2025): 629. https://doi.org/10.1200/jco.2025.43.5_suppl.629.

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629 Background: With the publication of the Surgery in Early Metastatic Seminoma Trial there has been increasing interest in the use of regional therapy as first line treatment (reserving systemic therapy for relapse) in patients with testicular seminoma with low volume with retroperitoneal lymphadenopathy. Herein, we sought to evaluate outcomes with both management approaches. Methods: A prospectively maintained single-institutional database was retrospectively queried for patients diagnosed between 1995-2016 with de novo clinical stage IIA/B (CSIIA/B) or who relapsed on surveillance (Rel-CSI

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4

Benakli, Malek, Arezki Tibiche, Nabil Yafour, et al. "Autologous Stem Cell Transplantation for Multiple Myeloma in Algeria." Blood 142, Supplement 1 (2023): 4973. http://dx.doi.org/10.1182/blood-2023-174045.

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Introduction : High dose therapy (HDT) with autologous stem cell transplantation (ASCT) is a validated standard of treatment in eligible patients (pts) with multiple myeloma (MM). It is associated with improved overall and event-free survival compared to conventional chemotherapy. We report here this first large retrospective multicentre study of activity and the outcomes of ASCT in MM pts for a long period (1998-2021) in Algeria. Patients and methods: Over a period of 23 years, from April 1998 to December 2021, 1117 pts with MM (mainly of the IgG type: 604 pts, 54.1%) benefited from ASCT in 8

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5

Zaslavsky, Oleg, Trevor Cohen, Kuan-Ching Wu, Jessica Jin, Shao-Yun Chien, and Serguei Pakhomov. "PROTOCOLS FOR COLLECTING CONVERSATIONAL LANGUAGE IN PERSONS WITH DEMENTIA." Innovation in Aging 7, Supplement_1 (2023): 746–47. http://dx.doi.org/10.1093/geroni/igad104.2415.

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Abstract We describe first-of-its-kind protocols for collecting spontaneous conversations in persons with dementia living in a community through conversation elicitation tools twice a month over six months. We also describe the preliminary feasibility of the protocol deployment in the first enrolled participants over the first month of data collection. Participants were recruited from the University of Washington ADRC registry. The audio was captured using RODE wireless microphone system. Four conversational elicitation techniques were used: 1) reminiscence using personal photographs; 2) remin

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6

Nickel, J. Curtis, Joe Downey, Francois Bénard, et al. "The Canadian Benign Prostatic Hyperplasia Audit Study (CanBas)." Canadian Urological Association Journal 2, no. 4 (2013): 367. http://dx.doi.org/10.5489/cuaj.629.

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Objective: To determine the prevalence, diagnostic patterns and management of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) in Canadian urology outpatient practice.Methods: Representative urologists were randomly selected from lists provided by the Canadian and Quebec Urological Associations. Each patient identified with a BPH diagnosis during a typical 2-consecutive-week period during April, May or June 2007 was asked to complete a corresponding International Prostate Symptom Score (IPSS) questionnaire. Each day, the participant urologist completed an

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7

Saburtsev, Sergey A. "Retrospective Assessment of the Health Status of Primary School Children Studying at the “Gymnasium” Educational Institution in Arzamas (Nizhny Novgorod Region)." Journal of Medical and Biological Research, no. 3 (September 1, 2023): 321–28. http://dx.doi.org/10.37482/2687-1491-z145.

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The purpose of this article was to assess the health status of primary school-age children who attended the “Gymnasium” municipal budgetary general education institution in Arzamas in 2014–2019. Materials and methods. A total of 1464 medical charts of firstto fourth-formers (in 2014–2019), of which 629 were boys and 835 were girls, were studied. Their health status and physical education groups were determined, their main diseases were identified. The number of children examined was 238 in 2014, 232 in 2015, 237 in 2016, 245 in 2017, 252 in 2018, and 260 in 2019. Results. The analysis of child

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8

Staib, James, Kierstin Catlett, and Stacey Dacosta Byfield. "Abstract P3-14-07: Breast cancer screening disparities among insured women in the Washington DC-Baltimore area." Cancer Research 82, no. 4_Supplement (2022): P3–14–07—P3–14–07. http://dx.doi.org/10.1158/1538-7445.sabcs21-p3-14-07.

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Abstract Background: Breast cancer screening (BCS) gaps have closed between non-Hispanic Black (NHB) and non-Hispanic White women when adjusted for covariates including insurance. However, gaps in breast cancer (BC) mortality persist. Washington DC and Baltimore (DC-Balt) are two high-resource cities with diverse populations, low BCS uptake, and high BC mortality. This analysis investigates the association between residence in a high NHB area and BCS uptake. Methods: This retrospective analysis used de-identified administrative data (2017–2019) from a large national US health insurer and publi

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9

Park, Jin Hyun, Kyung-Hun Lee, Sae-Won Han, et al. "The role of palliative resection in metastatic colorectal cancer: 10 years of experiences from a single institute." Journal of Clinical Oncology 30, no. 4_suppl (2012): 626. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.626.

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626 Background: Systemic chemotherapy is still mainstay of treatment of metastatic colorectal cancer (mCRC), while the role of palliative resection is not convincing. We intended to find out the role of palliative resection in mCRC. Methods: A total of 1,015 patients were diagnosed with mCRC at Seoul National University Hospital between 2000 and 2009. Except 169 patients who received curative metastectomy of liver and/or lung, 847 patients were retrospectively analyzed. Results: Out of 847 patients, 556 (65.6%) had metastasis at the time of diagnosis and 291 (34.4%) had recurrence after surger

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10

Fujii, Tatsuya, Tomohiro Ozawa, Yasuhiro Funahashi, Koichiro Jitsukawa, and Hideki Masuda. "Synthesis of Mononuclear Non-Heme Iron(III)-Hydroperoxo Complex as an Oxidative Catalyst." Advanced Materials Research 11-12 (February 2006): 331–34. http://dx.doi.org/10.4028/www.scientific.net/amr.11-12.331.

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Mononuclear FeII complex [FeII(ppba)]2+ (ppba = (6-pivalamido-2-pyridylmethyl) (2-pyridylmethyl)tert-butylamine) (1) has been synthesized and structurally characterized. The addition of H2O2 (10eq) to an acetone solution of 1 at -78°C generated FeIIIPPBA-OOH species, accompanied by a color change from pale yellow to reddish purple, which showed an intense absorption band corresponding to LMCT band (HOO- to Fe) at 528 nm (ε = 1120 M-1cm-1). The ESR spectrum for FeIIIPPBA-OOH species (g// = 4.22, g⊥ = 7.70 in acetone at 77 K) was typical of a high-spin FeIII species, suggesting that the FeIIIPPB

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11

Wardiana, Edi, Juniaty Towaha, and Syafaruddin Syafaruddin. "Pengelompokan 33 Aksesi Kakao Berdasarkan Karakter Morfologi Komponen Buah." Jurnal Tanaman Industri dan Penyegar 4, no. 2 (2017): 67. http://dx.doi.org/10.21082/jtidp.v4n2.2017.p67-78.

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<em>Identification and grouping of diverse cacao accessions based on morphological character of pod components is important in breeding activities to generate superior varieties. This study aimed to grouping 33 cocoa accessions based on morphological characters of pod components, conducted at Pakuwon Experimental Station, Sukabumi, West Java, at an altitude of 450 asl with Latosol soil and B type climate (Schmidt and Fergusson), from January until December 2015. Observation was taken on 33 cacao accessions of Kaliwining (KW), planted in 2012 with 3 m x 3 m spacing under 26 years old Genj

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12

Aiyengar, Rajarajan, and Jyoti Divecha. "Determination of Combined and Second Order Factor Effects for Simultaneous Optimization of Physical and Mechanical Properties of NR/BR Blend System." Tire Science and Technology 42, no. 4 (2014): 290–304. http://dx.doi.org/10.2346/tire.14.420404.

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ABSTRACT The blends of natural rubber (NR), polybutadiene rubber (BR), and other forms of rubbers are widely used for enhancing the mechanical and physical properties of rubber compounds. Lots of work has been done in conditioning and mixing of NR/BR blends to improve the properties of its rubber compounds and end products such as tire tread. This article employs response surface methodology designed experiments in five factors; high abrasion furnace carbon black (N 330), aromatic oil, NR/BR ratio, sulfur, and N-oxydiethylene-2-benzothiazole sulfenamide for determination of combined and second

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13

Lee, Choong-kun, Dong Hyun Seo, Daniel Aaron Fox, et al. "Impact of HER2-positivity on prognosis and targeted therapeutic outcomes in advanced biliary tract cancer." Journal of Clinical Oncology 43, no. 4_suppl (2025): 629. https://doi.org/10.1200/jco.2025.43.4_suppl.629.

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629 Background: HER2 overexpression and amplification have been identified as a promising druggable target in biliary tract cancer (BTC). This study aims to characterize the clinical and molecular outcomes associated with HER2 positivity in BTC and evaluate the prognostic implications of HER2-targeted therapies. Methods: A retrospective study was conducted involving patients with advanced BTC diagnosed at Yonsei Cancer Center (YCC) and the University of Texas MD Anderson Cancer Center (MDACC) between 2009 and 2023. Patients were classified as HER2-positive either by immunohistochemistry (IHC 3

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14

Devarajulu, Kavitha, and Prabu Velusamy. "A study of etiology, clinical profile and outcome in children aged 1-12 years presenting with fever of 1-3 weeks duration in a tertiary hospital." International Journal of Contemporary Pediatrics 6, no. 2 (2019): 569. http://dx.doi.org/10.18203/2349-3291.ijcp20190073.

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Background: The objective of the study was to find out the etiology, associated signs and symptoms of fever of 1-3 weeks in the age group of 1-12 years and their outcome following treatment in a tertiary care hospital.Methods: This was an observational prospective study conducted at Institute of child health and hospital for children, Egmore, Chennai during the period from January 2011 to October 2012. A total of 621 children aged 1-12 years with 1-3 weeks of fever were included in the study. Demographic, clinical and diagnostic data were collected and analyzed for each patient and outcome was

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15

Baumgartner, Christina K., Jonathan C. Roberts, Paula M. Jacobi, Sandra L. Haberichter, Qizhen Shi, and Robert R. Montgomery. "A Native Whole Blood Thrombin Generation Assay Allows Discrimination of Whole Blood Samples with FVIII Levels below 1%." Blood 124, no. 21 (2014): 4215. http://dx.doi.org/10.1182/blood.v124.21.4215.4215.

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Abstract Monitoring the correction of abnormal bleeding tendencies during the treatment of patients with hemostatic disorders is essential to evaluate success of therapy. While single clotting factor assays provide valuable information, global coagulation assays are desirable to better understand the overall hemostatic condition of patients. In Hemophilia A, severity of the clotting defect is traditionally evaluated by determining FVIII activity using chromogenic or clotting assays. Evaluation of thrombin generation in plasma samples for the assessment of bleeding tendencies in hemophilic pati

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16

Ishimoto, Chikako, Tsukasa Sugiyama, Toshimi Matsumoto, Hirohide Uenishi, Yasuyuki Fukumoto, and Miyoko Waki. "Full-scale simultaneous partial nitrification, anammox, and denitrification process for treating swine wastewater." Water Science and Technology 81, no. 3 (2020): 456–65. http://dx.doi.org/10.2166/wst.2020.120.

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Abstract A full-scale swine-wastewater activated sludge treatment plant that contains naturally enriched anammox biofilms was investigated for 2 years. Red biofilm in this system included Planctomycetes at a maximum of 62.5% of the total bacteria diversity, including Candidatus Jettenia and Candidatus Brocadia. The plant was operated with an influent containing 1,104 ± 513 mg/L biochemical oxygen demand (BOD) and 629 ± 198 mg/L total nitrogen (TN) (BOD/N of 1.78 ± 0.58) at a volumetric BOD loading rate of 0.32 ± 0.12 kg/m3/d. Notwithstanding drastically varying influent concentrations, BOD rem

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17

Francissen, C. M. T. P., R. F. D. van la Parra, A. H. Mulder, A. M. Bosch, and W. K. de Roos. "Evaluation of the Benefit of Routine Intraoperative Frozen Section Analysis of Sentinel Lymph Nodes in Breast Cancer." ISRN Oncology 2013 (September 16, 2013): 1–5. http://dx.doi.org/10.1155/2013/843793.

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Aims. Intraoperative analysis of the sentinel lymph node (SLN) by frozen section (FS) allows for immediate axillary lymph node dissection (ALND) in case of metastatic disease in patients with breast cancer. The aim of this study is to evaluate the benefit of intraoperative FS, with regard to false negative rate (FNR) and influence on operation time. Materials and Methods. Intraoperative analysis of the SLN by FS was performed on 628 patients between January 2005 and October 2009. Patients were retrospectively studied. Results. FS accurately predicted axillary status in 525 patients (83.6%). Th

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Tagawa, Scott T., Arjun V. Balar, Daniel P. Petrylak, et al. "Updated outcomes in TROPHY-U-01 cohort 1, a phase 2 study of sacituzumab govitecan (SG) in patients (pts) with metastatic urothelial cancer (mUC) that progressed after platinum (PT)-based chemotherapy and a checkpoint inhibitor (CPI)." Journal of Clinical Oncology 41, no. 6_suppl (2023): 526. http://dx.doi.org/10.1200/jco.2023.41.6_suppl.526.

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526 Background: SG is an antibody-drug conjugate composed of an anti-Trop-2 antibody coupled to SN-38, a topoisomerase-I inhibitor, via a proprietary hydrolyzable linker. SG received accelerated FDA approval in April 2021 in pts with mUC who previously received PT-based therapy and a CPI based on the primary analysis of the pivotal TROPHY-U-01 Cohort 1 study. With 9.1 mo median (med) follow-up, SG monotherapy demonstrated a 27% objective response rate (ORR) and med overall survival (OS) of 10.9 mo in 113 pts with locally advanced or mUC progressing after receiving at least a PT-based therapy a

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Siena, Salvatore, Maria Di Bartolomeo, Kanwal Pratap Singh Raghav, et al. "A phase II, multicenter, open-label study of trastuzumab deruxtecan (T-DXd; DS-8201) in patients (pts) with HER2-expressing metastatic colorectal cancer (mCRC): DESTINY-CRC01." Journal of Clinical Oncology 38, no. 15_suppl (2020): 4000. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.4000.

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4000 Background: T-DXd is an antibody-drug conjugate composed of an anti-HER2 antibody, cleavable tetrapeptide-based linker, and topoisomerase I inhibitor payload. Early studies have shown promising activity in advanced HER2-expressing tumors. DESTINY-CRC01 (DS8201-A-J203; NCT03384940) is a phase 2, open-label, multicenter study of T-DXd in pts with HER2-expressing mCRC. Methods: Pts with centrally confirmed HER2-expressing, RAS–wild type mCRC that progressed on ≥ 2 prior regimens received T-DXd 6.4 mg/kg every 3 weeks (q3w) in 3 cohorts (A: HER2 IHC 3+ or IHC 2+/ISH+; B: IHC 2+/ISH−; C: IHC 1

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Chablani, Priyanka, Theodore Karrison, and Walter Stadler. "629 Evaluation of provider preferences in first-line metastatic renal cell carcinoma: comparison between dual immunotherapy vs. immunotherapy/tyrosine kinase inhibitors." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (2021): A659. http://dx.doi.org/10.1136/jitc-2021-sitc2021.629.

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BackgroundDual immunotherapy (ipilimumab/nivolumab, IO/IO) and immunotherapy/tyrosine kinase inhibitor (IO/TKI) combinations (e.g. pembrolizumab/axitinib) are approved for first-line therapy of intermediate/poor risk metastatic renal cell carcinoma (RCC),1–4 but there is limited comparative data between these two options. We sought to understand how physicians decide between IO/IO vs. IO/TKI for this indication.MethodsWe sent a 10-question survey focused on a patient scenario of intermediate/poor risk metastatic RCC to 294 general and academic/disease-focused oncologists throughout the country

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Lang, Sally A., and Michael B. Maron. "Effect of neuropeptide Y on hemodynamics of the rabbit lung." Journal of Applied Physiology 84, no. 2 (1998): 618–23. http://dx.doi.org/10.1152/jappl.1998.84.2.618.

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Lang, Sally A., and Michael B. Maron.Effect of neuropeptide Y on hemodynamics of the rabbit lung. J. Appl. Physiol. 84(2): 618–623, 1998.—We evaluated the effect of neuropeptide Y (NPY) on the hemodynamics of the isolated rabbit lung perfused at constant flow and outflow pressure. Doses of 10−8 and 10− 7 M NPY increased pulmonary arterial pressure (Ppa) from 11.5 ± 1.0 (SE) mmHg to, respectively, 16.4 ± 1.5 and 26.0 ± 3.8 mmHg ( P < 0.05, n = 5 mmHg lungs), with 78 ± 4% of the increase at 10−7 M resulting from an increased arterial resistance. At the latter dose, pulmonary capillary pressur

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22

Spielmann, Marc, Henri Roché, Thierry Delozier, et al. "Trastuzumab for Patients With Axillary-Node–Positive Breast Cancer: Results of the FNCLCC-PACS 04 Trial." Journal of Clinical Oncology 27, no. 36 (2009): 6129–34. http://dx.doi.org/10.1200/jco.2009.23.0946.

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Purpose To evaluate the efficacy of trastuzumab in patients with node-positive breast cancer treated with surgery, adjuvant chemotherapy, radiotherapy, and hormone therapy if applicable. Patients and Methods Three thousand ten patients with operable node-positive breast cancer were randomly assigned to receive adjuvant anthracycline-based chemotherapy with or without docetaxel. Patients who presented human epidermal growth factor receptor 2 (HER2) -overexpressing tumors were secondary randomly assigned to either a sequential regimen of trastuzumab (6 mg/kg every 3 weeks) for 1 year or observat

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Fabrikantov, O. L., I. V. Lev, and N. M. Agarkov. "Biomarkers of Allostatic Load in Patients with Diabetic Retinopathy." Ophthalmology in Russia 19, no. 3 (2022): 624–29. http://dx.doi.org/10.18008/1816-5095-2022-3-624-629.

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Diabetic retinopathy occupies a special place among the causes of the progression of decrease and loss of visual acuity, significantly impairing the quality of life and age-related viability, an integral indicator that is considered allostatic load. However, the allostatic load in patients suffering from diabetic retinopathy, as well as in other ophthalmological diseases, has not been practically studied and biomarkers characterizing the allostatic load of patients with diabetic retinopathy remain unknown.Purpose. To study of allostatic load in patients with diabetic retinopathy and the identi

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Ritter, Amit, Aviram Mizrachi, Gideon Bachar, et al. "Detecting Recurrence Following Lobectomy for Thyroid Cancer: Role of Thyroglobulin and Thyroglobulin Antibodies." Journal of Clinical Endocrinology & Metabolism 105, no. 6 (2020): e2145-e2151. http://dx.doi.org/10.1210/clinem/dgaa152.

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Abstract Background The use of thyroglobulin (Tg) and thyroglobulin antibodies (TgAb) for detecting disease recurrence is well validated following total thyroidectomy and radioiodine ablation. However, limited data are available for patients treated with thyroid lobectomy. Methods Patients who had lobectomy for papillary thyroid cancer followed for &gt;1 year, with sufficient data on Tg and TgAb, including subgroup analysis for Hashimoto’s thyroiditis and contralateral nodules. Results One-hundred sixty-seven patients met the inclusion criteria. Average tumor size was 9.5 ± 6 mm. Following

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Porkka, Kimmo, Bengt Simonsson, Herve Dombret, et al. "Efficacy of Dasatinib in Patients with Philadelphia-Chromosome-Positive Acute Lymphoblastic Leukemia Who Are Resistant or Intolerant to Imatinib: 2-Year Follow-Up Data from START-L (CA180-015)." Blood 110, no. 11 (2007): 2810. http://dx.doi.org/10.1182/blood.v110.11.2810.2810.

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Abstract Patients with Philadelphia-chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) generally have a rapid disease course and a poor overall prognosis that is compounded by resistance to imatinib. Dasatinib is a novel multi-targeted kinase inhibitor of BCR-ABL and SRC family kinases, with in vitro potency some 325-fold greater than imatinib against BCR-ABL and proven efficacy in this patient population. START-L is an open-label, international, multicenter study in which patients with imatinib-resistant or -intolerant Ph+ ALL enrolled from January through July 2005 were treated with

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Schäufele, Martina, Siegfried Weyerer, Ingrid Hendlmeier, and Leonore Köhler. "Alkoholbezogene Störungen bei Menschen in Einrichtungen der stationären Altenhilfe: eine bundesweite repräsentative Studie." SUCHT 55, no. 5 (2009): 292–302. http://dx.doi.org/10.1024/2009.05.04.

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Fragestellung: Ziel der Studie war es, erstmals in Deutschland auf der Grundlage einer bundesweiten repräsentativen Stichprobe die Prävalenz alkoholbezogener Störungen und damit assoziierte Charakteristika in der Bewohnerschaft von Altenpflegeheimen zu ermitteln. </p><p> Methodik: Ausgehend von einer für Deutschland repräsentativen Zufallsstichprobe von 609 vollstationären Pflegeeinrichtungen (Erhebung durch TNS Infratest Sozialforschung), wurde durch ein zweistufiges geschichtetes Zufallsverfahren eine Substichprobe (Stufe 1: N=185 Heime; Stufe 2: N=86 Heime) für die vorliegende U

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Cruz, José Henrique de Araújo, Lindoaldo Xavier Sousa, Bruno Firmino de Oliveira, Francisco Patrício de Andrade Júnior, Maria Angélica Satyro Gomes Alves, and Abrahão Alves de Oliveira Filho. "Disfunção temporomandibular: revisão sistematizada." ARCHIVES OF HEALTH INVESTIGATION 9, no. 6 (2020): 570–75. http://dx.doi.org/10.21270/archi.v9i6.3011.

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Introdução: Disfunção Temporomandibular (DTM) é o termo para designar um quadro de desorganização neuromuscular identificada pela presença de cefaleias crônicas, sons na articulação temporomandibular, restrições dos movimentos mandibulares, hiperestesia e dor nos músculos da mastigação, da cabeça e do pescoço. Objetivo: realizar uma revisão de literatura sobre a DTM. Material e Método: foi feita uma seleção de artigos científicos a partir das bases de dados LILACS e SCIELO utilizando os descritores “Articulação Temporomandibular”, “Transtornos da Articulação Temporomandibular” e “Dor Facial”,

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Rowe, Jacob M., Haesook T. Kim, Peter A. Cassileth, Mark R. Litzow, Peter H. Wiernik, and Martin S. Tallman. "Time To Complete Remission Is Not a Significant Prognostic Factor in AML: A Report on 1,959 Consecutive Patients Registered to 6 Studies of the Eastern Cooperative Oncology Group (ECOG)." Blood 104, no. 11 (2004): 862. http://dx.doi.org/10.1182/blood.v104.11.862.862.

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Abstract Prognostic factors for AML at diagnosis include cytogenetics, FLT3 ITD, age, MDR status and white cell count at presentation. Several groups (Blood2000; 95:72; BJH1999; 107:69; Haematologica2004; 89:528) have reported that time to achievement of complete remission (CR) is an independent post-induction prognostic factor in AML. Furthermore, some investigators have classified patients who do not achieve CR with one cycle as primary induction failure. Between 1983 and 1993 1,959 patients were registered to 6 consecutive ECOG studies (E3483, PC486, E1490, E2491/INT0129, E3489 and E3993).

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Caillaud, Corinne, Cyrille Le Creff, Patrick Legros, and André Denjean. "Strenuous Exercise Increases Plasmatic and Urinary Leukotriene E4 in Cyclists." Canadian Journal of Applied Physiology 28, no. 6 (2003): 793–806. http://dx.doi.org/10.1139/h03-059.

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The purpose of this study was to investigate plasma and urinary levels of leukotriene (LT) and the changes in pulmonary function induced by strenuous exercise in highly trained cyclists (HT) with mild exercised-induced hypoxemia (EIH). Method: Nine HT and five untrained subjects (UT) performed a 30-min exercise at 78% of their [Formula: see text] Leukotriene E4 (LTE4) was assayed in plasma and urine. Pulmonary function tests and pulmonary diffusion capacity (DLCO) were examined before and after exercising. Ear arterialized blood gases were assessed at rest and during exercise. Results: The mea

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Borno, Hala, Patricia Li, Sylvia Zhang, et al. "Implementation of clinician-facing prostate cancer therapeutic clinical trial decision tool at a comprehensive cancer center." Journal of Clinical Oncology 39, no. 6_suppl (2021): 19. http://dx.doi.org/10.1200/jco.2021.39.6_suppl.19.

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19 Background: The conventional model for clinical trial (CT) recruitment relies on clinicians to identify potential CTs for patients. Internet technology can be leveraged as a decision tool to enhance the CT recruitment process. Methods: An internet-based, clinician-facing decision tool was developed in genitourinary medical oncology clinic at a Comprehensive Cancer Center (CCC). The tool provided access to a real-time, tailored list of treatment CTs actively recruiting patients with PCa at the CCC based on clinical characteristics inputted by user. The clinical data was summarized. All clini

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Kirkwood, M. Kelsey, Laura A. Levit, Melissa Kate Accordino, et al. "Does exposure matter? Association between exposure to clinical trial conduct during training and intent to participate in clinical trials post-training among oncology fellows: An ASCO State of Cancer Care in America study." JCO Oncology Practice 20, no. 10_suppl (2024): 69. http://dx.doi.org/10.1200/op.2024.20.10_suppl.69.

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69 Background: Clinical trials are part of standard cancer care. Yet, a quarter of oncology fellows in a 2023 survey reported feeling underprepared to conduct research after training and nearly half did not identify research as important to their practice. In a 2024 survey, we explore the impact of exposure to research activities in fellowship on intentions to conduct research post-training. Methods: Fellows who took the 2024 ASCO Medical Oncology In-Training Exam (ITE) were invited to an optional IRB-exempted post-exam survey to measure (1) research exposure during training and (2) anticipate

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Poladia, Bhavesh, Vijay Patil, Vanita Noronha, et al. "Acute toxicity of neoadjuvant chemotherapy in oral cavity cancers: Can it be predicted?" Journal of Clinical Oncology 31, no. 15_suppl (2013): e17027-e17027. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e17027.

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e17027 Background: Neoadjuvant chemotherapy administration is associated with significant amount of morbidity and around 2-3% mortality in the Western world protocol settings. In developing countries where malnourishment is prevalent, the same data might not apply. Methods: This analysis was performed on a database of patients undergoing NACT for oral cancers at our center from 2010- 2012. The toxicity was graded according to CTCAE version 4.02 scale. Descriptive analysis, univariate and multivariate analysis were performed to determine factors affecting toxicity. Results: There were 528 patie

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Nute, Drew W., Nicholas Kusnezov, and Brian R. Waterman. "Functional Outcomes and Complications Following Pectoralis Major Tendon Allograft Reconstruction in a Military Population." Orthopaedic Journal of Sports Medicine 7, no. 10 (2019): 232596711987870. http://dx.doi.org/10.1177/2325967119878709.

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Background: There are limited data available regarding outcomes following pectoralis major tendon (PMT) reconstruction with allograft. Purpose: To evaluate the functional outcomes and complication profile following PMT reconstruction with allograft in a military population. Study Design: Case series; Level of evidence, 4. Methods: All active duty military personnel who underwent PMT allograft reconstruction between 2008 and 2013 were identified. Demographics, injury characteristics, and surgical technique were recorded from the electronic medical record. Self-reported pain scores and manual st

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Schnittger, Susanne, Christiane Eder, Tamara Alpermann, et al. "Analysis of the IDH1G105 (SNPrs11554137) Polymorphism in 961 AML Patients and in a Large Cohort of 475 Healthy Controls." Blood 118, no. 21 (2011): 2518. http://dx.doi.org/10.1182/blood.v118.21.2518.2518.

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Abstract Abstract 2518 Introduction: Mutations in IDH1 and IHD2 at arginines 132 and 140 or 172, respectively, have recently been shown to play an important role in AML. Also the IDH1105GGT minor allele of the IDH1G105 (SNPrs11554137) polymorphism that is localized in the same exon as the IDH1R132 mutation has recently been reported to be an adverse prognostic factor in AML (JCO: 14, 2356–2364, 2010). Aim: We aimed at further delineating the frequency and impact of the IDH1105GGT minor allele in AML and also analyzed a healthy control cohort. Methods:IDH1G105 (SNPrs11554137) was analyzed in 96

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Caporali, R., D. Aletaha, R. Sanmartí, et al. "POS0682 LONG-TERM EFFICACY OF BARICITINIB IN PATIENTS WITH RHEUMATOID ARTHRITIS WITH INADEQUATE RESPONSE TO bDMARDs: RESULTS FROM RA-BEYOND FOLLOWING 6.9 YEARS OF TREATMENT." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 617.2–618. http://dx.doi.org/10.1136/annrheumdis-2022-eular.1759.

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BackgroundBaricitinib (BARI), an oral selective Janus kinase 1/2 inhibitor, is approved for treatment of adults with moderately-to-severely active rheumatoid arthritis (RA). BARI demonstrated efficacy in patients (pts) with RA who have inadequate response to biologic disease-modifying antirheumatic drugs (bDMARD-IR) in a 24-week (wk) phase 3 study, RA-BEACON.1 BARI efficacy was evaluated up to 3 years (yrs) of treatment in a long-term extension (LTE) study, RA-BEYOND.2ObjectivesDisclose long-term efficacy of BARI 4 mg and 2 mg in bDMARD-IR pts in the completed study RA-BEYOND.MethodsIn RA-BEAC

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Petrov, A. V., Y. O. Shevnina, A. S. Gaffarova, and A. A. Petrov. "Dynamic of radiographic and ultrasonographic indices of hip joints in patients with ankylosing spondylitis under treatment with tumor necrotic factor ― alpha inhibitors." Medical alphabet 2, no. 37 (2020): 54–58. http://dx.doi.org/10.33667/2078-5631-2019-2-37(412)-54-58.

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Background. Inflammation of the hip joints in ankylosing spondylitis (AS) is a frequent and severe manifestation of the disease, which in 7–8 % of patients is accompanied by the requirements of hip joints prosthesis. In the treatment of hip arthritis associated with AS non-steroidal anti-inflammatory drugs (NSAIDs), sulfasalazine (SSZ) and tumor necrosis factor-alpha blockers were used. However, the influence of these treatment on the dynamics of structural changes in hip joints is not studied.Purpose. To evaluate the dynamics of clinical, radiologic and ultrasonographic indices of hip joints

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Dulcey-Sarmiento, Luis Andrés, Jhon Fredy Castillo-Blanco, Juan Sebastian Theran-Leon, Riamondo Caltagirone-Miceli, and Melissa Julieth Aguas-Cantillo. "Utilidad del Índice ROX Como Predictor de Fallo Respiratorio, Mortalidad y Complicaciones en Pacientes con COVID-19 Sin Soporte Ventilatorio Invasivo, Estudio Unicentrico." Revista de Medicina Clínica 6, no. 2 (2022): e01082206015. https://doi.org/10.5281/zenodo.6949776.

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<strong>Introducción:</strong> El uso del índice de ROX en pacientes COVID-19 permite evaluar aquellos con alto riesgo de fallo ventilatorio, sin embargo, no ha sido validado abiertamente en pacientes que usen mascarilla con reservorio tipo Hudson. <strong>Pacientes y Métodos:</strong> estudio retrospectivo de 306 adultos infectados por SARS-CoV2 mediante prueba antigénica o molecular. El objetivo principal fue evaluar el papel del índice ROX como predictor de fallo respiratorio y mortalidad. En el análisis estadístico inferencial se u

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Fernandes, Pedro Henrique Jota, Yijie Xiong, Shelby L. Davies-Jenkins, Biquan Zhao, and Mary E. Drewnoski. "218 Comparison between vegetation indices to estimate biomass in cereal rye." Journal of Animal Science 102, Supplement_3 (2024): 183–84. http://dx.doi.org/10.1093/jas/skae234.215.

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Abstract Accurate forage mass estimation can lead to improved pasture management, but it requires a significant investment of time on the ground sampling. The use of satellite images has potential to reduce the time needed and thus, expediting decision-making processes. Satellite measure various spectral wavelengths of light reflected by plants (i.e., reflectance), and using satellite images, various vegetation indices (VI) can be calculated, such as the Normalized Difference Vegetation Index (NDVI), the Enhanced Vegetation Index (EVI), the Green Normalized Difference Vegetation Index (GNDVI),

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Spiteller, G. "Organikers Methodenbuch: Analytische und präparative Labormethoden. Von K. E. Geckeler und H. Eckstein. Friedrich Vieweg u. Sohn Verlagsgesellschaft mbH, Braunschweig - Wiesbaden 1987. 482 S., 323 Bilder, 74 Tab., geb., DM 78,-. ISBN 3-528-08447-2." Nachrichten aus Chemie, Technik und Laboratorium 36, no. 2 (1988): 187. http://dx.doi.org/10.1002/nadc.19880360215.

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Bellmunt, Joaquim, Thomas Powles, Roger Henriksson, et al. "Clinical outcomes and economic burden for bladder cancer patients: An analysis from a Swedish cancer registry." Journal of Clinical Oncology 38, no. 15_suppl (2020): 5026. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.5026.

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5026 Background: To investigate the clinical and economic disease burden for patients (pts) with non-muscle invasive bladder cancer (NMIBC), muscle invasive bladder cancer (MIBC), and metastatic urothelial carcinoma (mUC) using a Swedish bladder cancer registry. Methods: Pts diagnosed with bladder cancer in the Stockholm Gotland region between 2005-2013 were included and followed until May 31, 2015 or until death. MIBC was classified if a T, N, M at diagnosis was T2, T3, T4, N1, N2, N3, or M1, otherwise pts were classified as NMIBC. All diagnostic and therapeutic interventions were captured an

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Stelmach, Ramona, Stefanie Zschaebitz, Stella Erdmann, et al. "Comparing the effectiveness of IO-based combination regimens as first-line treatment for advanced clear-cell renal cell carcinoma (ccRCC)." Journal of Clinical Oncology 43, no. 5_suppl (2025): 498. https://doi.org/10.1200/jco.2025.43.5_suppl.498.

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498 Background: IO-based combination therapies - either in combination with tyrosine kinase inhibitors (TKI) or as double checkpoint inhibition - have revolutionized first-line treatment of ccRCC patients. We compared tolerability and effectiveness of ipilimumab plus nivolumab (ipi/nivo), cabozantinib plus nivolumab (cabo/nivo), axitinib plus pembrolizumab (axi/pem), and lenvatinib plus pembrolizumab (len/pem) as first-line treatment in real-world cohorts. Methods: Data from retrospective, multicenter cohorts of advanced ccRCC patients were analyzed. Best response was evaluated by local invest

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Hamm, P. B., S. L. Gieck, N. L. David, and R. M. Hunger. "First Report of Soilborne wheat mosaic virus on Wheat (Triticum aestivum) in the Columbia Basin of Oregon." Plant Disease 91, no. 11 (2007): 1513. http://dx.doi.org/10.1094/pdis-91-11-1513c.

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The Columbia Basin of Oregon consists of six counties (Gilliam, Hood River, Morrow, Sherman, Wasco, and Umatilla) and is the major wheat-producing region in the state. In 2005, these counties produced 300,277 ha of mostly fall-planted wheat. While primarily a dryland production area, wheat (approximately 8,094 ha) is also grown as a rotational crop under irrigation. Stunted and chlorotic winter wheat plants with leaves exhibiting a mosaic pattern consistent with that caused by Soilborne wheat mosaic virus (SBWMV) were observed in March 2005. These plants originated from four center-pivot irrig

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Becker, Pamela S., Sylvia Chien, Adrianne N. Wilks, John J. Hollowed, Frederick R. Appelbaum та William I. Bensinger. "Inhibition of αvβ3 Integrin Disrupts Adhesion and Enhances Chemotherapy Effect in Multiple Myeloma Cells." Blood 110, № 11 (2007): 4805. http://dx.doi.org/10.1182/blood.v110.11.4805.4805.

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Abstract Multiple myeloma cells adherent within the bone marrow microenvironment exhibit protection from chemotherapy. Myeloma cells express the αvβ3 receptor for fibronectin (Fn) and vitronectin (Vn), a receptor critical for tumor invasiveness and tumor angiogenesis. Disruption of angiogenesis or interference with adhesion of myeloma cells inhibits myeloma growth. Human myeloma cell line U266 exhibited 41% expression of αvβ3 integrin by flow cytometry using LM609 monoclonal antibody (Chemicon) or 82% using MEDI-522 humanized antibody (Abegrin™, kindly provided by Medimmune Oncology, Inc. and

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El-Shamy, Hasan M. "Twins/Zwillinge: A Broader View. A Contribution to Stith Thompson’s Incomplete Motif System—A Case of the Continuation of Pseudoscientific Fallacies †." Humanities 10, no. 1 (2020): 8. http://dx.doi.org/10.3390/h10010008.

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Explaining the rationale and main objectives for his motif system; Stith Thompson declared that it emulates what “the scientists have done with the worldwide phenomena of biology” (Thompson 1955, I, p. 10). In this respect; the underlying principles for motif identification and indexing are comparable to those devised by anthropologists at Yale for “categorizing” culture materials into 78 macro-units and 629 subdivisions thereof used to establish “The Human Relations Area Files” (HRAF). By comparison, 23 divisions (chapters) make up the spectrum of sociocultural materials covered in Thompson’s

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Guida, José, Fernanda Surita, Mary Parpinelli, and Maria Costa. "Preterm Preeclampsia and Timing of Delivery: A Systematic Literature Review." Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics 39, no. 11 (2017): 622–31. http://dx.doi.org/10.1055/s-0037-1604103.

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Introduction Preeclampsia, a multifactorial disease with pathophysiology not yet fully understood, is a major cause of maternal and perinatal morbidity and mortality, especially when preterm. The diagnosis is performed when there is an association between arterial hypertension and proteinuria or evidence of severity. There are unanswered questions in the literature considering the timing of delivery once preterm preeclampsia has been diagnosed, given the risk of developing maternal complications versus the risk of adverse perinatal outcomes associated with prematurity. The objective of this sy

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Rahman, P., I. Mcinnes, A. Deodhar, et al. "POS1028 GUSELKUMAB MAINTAINS RESOLUTION OF DACTYLITIS AND ENTHESITIS IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS: RESULTS THROUGH 2 YEARS FROM A PHASE 3 STUDY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 826–27. http://dx.doi.org/10.1136/annrheumdis-2022-eular.1337.

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BackgroundGuselkumab (GUS), a selective inhibitor of IL-23, significantly improved the diverse manifestations of active psoriatic arthritis (PsA), including dactylitis and enthesitis, in DISCOVER (D)-1 & 2 trials of patients (pts) with active PsA1,2, with maintenance of response rates through 1 year (yr).3,4 Dactylitis and enthesitis, extra-articular manifestations of PsA, can be difficult to treat and cause significant disease burden.5,6ObjectivesTo evaluate the ability of GUS to provide long-term resolution of dactylitis and enthesitis in pts with PsA through 2 yrs of D-2.MethodsD-2 biol

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Li, Kevin, Christopher J. Magnani, Selen Bozkurt, et al. "Practice-based evidence for factors associated with urinary incontinence following prostate cancer care." Journal of Clinical Oncology 36, no. 6_suppl (2018): 106. http://dx.doi.org/10.1200/jco.2018.36.6_suppl.106.

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106 Background: Urinary incontinence (UI) is a common complication following treatment for localized prostate cancer. Past studies evaluating UI risk factors use surveys or chart abstraction, which may be costly and lack generalizability. Electronic health records (EHR) allow us to examine UI at a population level. We applied data mining methods to EHR data to: (1) evaluate rates of UI following prostate cancer treatment; and (2) evaluate potential risk factors for posttreatment UI. Methods: We conducted a retrospective analysis of patients undergoing prostatectomy or radiation therapy for loc

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Volandes, Angelo E., Sophia N. Zupanc, Joshua R. Lakin, et al. "Video Intervention and Goals-of-Care Documentation in Hospitalized Older Adults." JAMA Network Open 6, no. 9 (2023): e2332556. http://dx.doi.org/10.1001/jamanetworkopen.2023.32556.

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ImportanceDespite the benefits of goals-of-care (GOC) communication, many hospitalized individuals never communicate their goals or preferences to clinicians.ObjectiveTo assess whether a GOC video intervention delivered by palliative care educators (PCEs) increased the rate of GOC documentation.Design, Setting, and ParticipantsThis pragmatic, stepped-wedge cluster randomized clinical trial included patients aged 65 years or older admitted to 1 of 14 units at 2 urban hospitals in New York and Boston from July 1, 2021, to October 31, 2022.InterventionThe intervention involved PCEs (social worker

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Yalcin, Yunus C., Nelianne Verkaik, Hannelore I. Bax, Peter D. Croughs, Ad J. J. C. Bogers, and Kadir Caliskan. "127. Novel Treatment Approach for Left Ventricular Assist Device-related Infections." Open Forum Infectious Diseases 6, Supplement_2 (2019): S92—S93. http://dx.doi.org/10.1093/ofid/ofz360.202.

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Abstract Background Left ventricular assist device (LVAD) implantation has become an effective treatment option for patients with severe heart failure. However, infections remain a substantial risk. Therefore, the aim of this study was to gain insight in the incidence and outcome of LVAD infections in our center and develop an up-to-date flowchart for the management of LVAD-related infections. Methods A retrospective study was performed which included all patients with an LVAD implanted between 2006 until 2019, along with a rigorous review of the current literature. Clinical records and microb

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Hu, Qingjiang, Koichi Suyama, Kazuma Kobayashi, et al. "Geriatric-8 (G8) screening tool stratified the efficacy of S-1 plus ramucirumab in elderly patients with advanced/recurrent gastric cancer: A post-hoc analysis of the KSCC1701 trial." Journal of Clinical Oncology 40, no. 4_suppl (2022): 256. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.256.

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256 Background: KSCC1701 trial showed the efficacy and safety of S-1 plus ramucirumab as a first-line treatment for elderly patients with advanced/recurrent gastric cancer. However, some frail patients may not benefit from S-1 plus ramucirumab. We aimed to clarify the usefulness of G8 screening tool for stratifying the efficacy and safety of S-1 plus ramucirumab therapy to elderly patients with advanced/recurrent gastric cancer. Methods: Patients aged 70 and older with previously untreated unresectable or recurrent gastric cancer were included from 23 institutes in Japan. They received S-1 (40

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