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Статті в журналах з теми "796.012.1:797 (043.2)"

Автор: Grafiati

Опубліковано: 30 травня 2022

Оновлено: 31 липня 2025

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1

Steen, R. W. J. "A comparison of wheat and barley as supplements to grass silage for finishing beef cattle." Animal Science 56, no. 1 (1993): 61–67. http://dx.doi.org/10.1017/s0003356100006164.

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AbstractTwo randomized-block experiments were carried out to examine the relative value of wheat and barley as supplements to grass silage for finishing beef cattle. In each experiment unwilted, formic acid-treated silage was offered ad libitum and supplemented with 500 g soya-bean meal and 50 g minerals and vitamins to 44 12-month-old bulls for 157 and 172 days in experiments 1 and 2 respectively. Twelve of the animals also received 2·5 kg rolled spring barley (LB), 12 received 4·0 kg barley (HB) and 20 received 3·25 kg rolled wheat (W). For experiments 1 and 2 respectively the barley contain

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2

M., V. BASAVESWARA RAO, R. SURESH J., KUMAR ARVIND, ILA H., and JUNJAPPA H. "Reaction of Ketene Dithioacetals with Aziridine. A New Synthesis of N-Vinylaziridines and their Iodide Ion-assisted Rearrangement to Pyrrolines." Journal of Indian Chemical Society Vol. 74, Nov-Dec 1997 (1997): 955–60. https://doi.org/10.5281/zenodo.5900960.

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Department of Chemistry, North-Eastern Hill University, Shillong-793 003 Department of Chemistry, Indian Institute of Technology, Kanpur-208 016 <em>Manuscript received 16 October 1997</em> The ketene dithloacetals 1, 4, 9 and 11 react readily with aziridine 2 to give the corresponding <em>N</em>-vinylaziridines 3, 5, 8 and 12 respectively, which on iodide ion-catalyzed rearrangement undergo ring expansion to give pyrrolines 14, 18, 21 and 22 respectively.

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3

Yirga, Hirut Y., Arthur L. Goetsch, Ryszard Puchala, et al. "PSII-2 Effects of Natural Sources of Brackish/Saline Water on Water and Feed Intake, Digestion, Physiological Conditions, and Performance of Yearling Meat Goats." Journal of Animal Science 101, Supplement_3 (2023): 655–56. http://dx.doi.org/10.1093/jas/skad281.762.

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Abstract This experiment was aimed to determine how variables such as water intake, feed intake, ruminal conditions, digestion, blood constituent levels, energy metabolism, and performance of yearling meat goats are influenced by different natural sources of brackish/saline water. Two animal types (AT), 18 Boer (BOE) and 18 Spanish (SPA) doelings, with the age of 8.9 ± 0.306, and 9.7 ± 0.212 months, respectively were used for the experiment which lasted 17 weeks (16 weeks for the experiment and 1 week of adaptation). Drinking water treatments were fresh water (FRW), West pasture Brackish water

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4

Anupam, Bhim, Baishya Saranga, Gurusamy Sivakumar, Gopalakrishnan Jagannatha, and Natarajan Srinivasan. "Realising blue colour in cobalt substituted silicates: Synthesis, structure and optical studies." Journal of India Chemical Society Vol. 95, Dec 2018 (2018): 1579–86. https://doi.org/10.5281/zenodo.5644818.

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Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore-560 012, India <em>E-mail</em>: snatarajan@iisc.ac.in Summer Research Fellow, National Institute of Technology, Shillong-793 003, Meghalaya, India <em>Manuscript received online 30 December 2018, accepted 31 December 2018</em> In an attempt to develop new blue coloured inorganic oxides, we have undertaken the cobalt substitution in Zn<sub>2</sub>SiO<sub>4</sub> and Ba<sub>2</sub>ZnSi<sub>2</sub>O<sub>7</sub>. In both the compounds, Zn occupies a tetrahedral coordination. Our studies indicate formation of single-p

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5

Cassiano-Quezada, Fabiola, José Torres-Ruiz, Jennifer Balderas-Miranda, et al. "INTRACYTOPLASMIC TOLL- LIKE RECEPTORS (TLR) 7, 9 AND MYD88 IN PERIPHERICAL B CELL SUBSETS AS A PREDICTOR OF RENAL RESPONSE IN PATIENTS WITH LUPUS NEPHRITIS." Journal of Rheumatology 52, Suppl 1 (2025): 158.1–158. https://doi.org/10.3899/jrheum.2025-0390.pv134.

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PV134 / #630Poster Topic:AS16 - Lupus Nephritis-PathogenesisBackground/PurposeA gain of-function mutation within TLR7 was identified in a SLE murine model and increased the survival of B lymphocytes, age associated B cells (ABCs), extrafollicular B lymphocytes and autoantibodies production, mediated by MyD88. The aim of this study is to analyze the role of TLR7, 9 and MyD88 expression in diverse B cell subsets as renal response predictors in patients with lupus nephritis.MethodsWe included SLE patients who fulfilled the ACR/EULAR 2019 classification criteria and active proliferative LN (Class

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6

Mujika, Iñigo. "Olympic Preparation of a World-Class Female Triathlete." International Journal of Sports Physiology and Performance 9, no. 4 (2014): 727–31. http://dx.doi.org/10.1123/ijspp.2013-0245.

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Detailed accounts of the training programs followed by today’s elite triathletes are lacking in the sport-science literature. This study reports on the training program of a world-class female triathlete preparing to compete in the London 2012 Olympic Games. Over 50 wk, she performed 796 sessions (303 swim, 194 bike, 254 run, 45 strength training), ie, 16 ± 4 sessions/wk (mean ± SD). Swim, bike, and run training volumes were, respectively, 1230 km (25 ± 8 km/wk), 427 h (9 ± 3 h/wk), and 250 h (5 ± 2 h/wk). Training tasks were categorized and prescribed based on heart-rate values and/or speeds

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7

Lecarpentier, Y., F. X. Blanc, S. Salmeron, J. C. Pourny, D. Chemla, and C. Coirault. "Myosin cross-bridge kinetics in airway smooth muscle: a comparative study of humans, rats, and rabbits." American Journal of Physiology-Lung Cellular and Molecular Physiology 282, no. 1 (2002): L83—L90. http://dx.doi.org/10.1152/ajplung.2002.282.1.l83.

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To analyze the kinetics and unitary force of cross bridges (CBs) in airway smooth muscle (ASM), we proposed a new formalism of Huxley's equations adapted to nonsarcomeric muscles (Huxley AF. Prog Biophys Biophys Chem7: 255–318, 1957). These equations were applied to ASM from rabbits, rats, and humans ( n = 12/group). We tested the hypothesis that species differences in whole ASM mechanics were related to differences in CB mechanics. We calculated the total CB number per square millimeter at peak isometric tension (Ψ ×109), CB unitary force (Π), and the rate constants for CB attachment ( f 1) a

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8

Aonso-Diego, G., Á. García-Pérez, S. Weidberg, and R. Secades-Villa. "Predictors of smoking cessation treatment attrition in individuals with substance use disorders." European Psychiatry 64, S1 (2021): S823. http://dx.doi.org/10.1192/j.eurpsy.2021.2175.

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IntroductionAttrition rates in smoking cessation treatments are high, particularly in persons with substance use disorders. It is estimated that about 55%% disengage prematurely at treatment, meaning that a large portion will not benefit from smoking abstinence. So far, no previous studies have examined predictors of dropouts in a smoking cessation treatment with persons with SUD.ObjectivesThe study was two-fold: 1) to analyze the percentage of early-, late-dropouts and completers, and 2) to examine sociodemographic, psychological, and substance-related predictors of dropouts.MethodsA total of

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9

Galvis, Jason Onell Ardila, José Henrique Hildebrand Grisi-Filho, Daniele Da Costa, et al. "Epidemiologic characterization of bovine tuberculosis in the State of Espírito Santo, Brazil." Semina: Ciências Agrárias 37, no. 5Supl2 (2016): 3567. http://dx.doi.org/10.5433/1679-0359.2016v37n5supl2p3567.

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A cross-sectional study was carried out between January 2012 and May 2014 to investigate the status of bovine tuberculosis in the state of Espírito Santo. The state was divided into two regions, and in each of them, 300 farms with reproductive activity were randomly selected and considered as the primary sampling units. In the selected farms, a fixed number of female bovines aged over 2 years were randomly selected to undergo a comparative cervical tuberculin test; an epidemiologic questionnaire was also applied. In the state of Espírito Santo, the apparent prevalence of tuberculosis-positive

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10

Jeong, Sun Young, Myung Jin Chung, Gukmyung Choi, Bong Soo Kim, Seung Hyun Kim, and Ji Kang Park. "A Comparison between Liquid-Crystal Display Monitors and Cathode-Ray Tube Monitors: A Combined Assessment Study of Observer Performances by Using Storage Phosphor and Flat-Panel-Detector Radiography in Detecting Experimentally Induced Pulmonary Edema in." Journal of Medicine and Life Science 6, no. 5 (2009): 351–58. http://dx.doi.org/10.22730/jmls.2009.6.5.351.

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To compare the observer performance 0f liquid crystal display (LCO) and cathode ray tube (CRT) monitors in detecting experimentally induced pulmonary edema in pigs by using soft-copy images of amorphous selenium-based flat-panel-detector radiography (OR) and storage phosphor computed radiography (CR). Oleic acid was injected intra-atrially into three pigs (weight, 20-25kg) at doses of 0.04, 0.05, and 0.06 ml/kg to induce pulmonary edema. Each set of CR, DR, and thin-section CT scans were obtained every 20-30 minutes from three pigs over 4-6hours. Thus, 37 sets (10 sets from pig-1, 11 sets from

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11

Loyola Filho, Antônio Ignácio de, Elizabeth Uchoa, Henrique L. Guerra, Josélia O. A. Firmo, and Maria Fernanda Lima-Costa. "Prevalência e fatores associados à automedicação: resultados do projeto Bambuí." Revista de Saúde Pública 36, no. 1 (2002): 55–62. http://dx.doi.org/10.1590/s0034-89102002000100009.

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OBJETIVO: Realizou-se estudo com base populacional na cidade de Bambuí, MG, com cerca de 15.000 habitantes, para determinar a prevalência e os fatores associados ao uso de automedicação. MÉTODOS: Foi selecionada uma amostra aleatória simples de 1.221 moradores com idade >18 anos: 796 relataram uso de medicamentos nos últimos 90 dias e foram incluídos no estudo (775 participaram). A coleta de dados foi feita por entrevistas domiciliares. Foram considerados três grupos de variáveis exploratórias: sociodemográficas, indicadores de condição de saúde e indicadores de uso de serviços de saúde. Pa

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12

Bowden, Francis J., Elissa J. O'Keefe, Ruth Primrose, and Marian J. Currie. "Sexually transmitted infections, blood-borne viruses and risk behaviour in an Australian senior high school population—the SHLiRP study." Sexual Health 2, no. 4 (2005): 229. http://dx.doi.org/10.1071/sh05014.

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Objectives: To determine the feasibility and acceptability of screening for sexually transmitted infections and blood-borne viruses and to study the profile of sexual activity and other risk behaviours in a senior high school population. Methods: In this descriptive study we provided sexual health education and screening to students from two senior high schools in the Australian Capital Territory. We collected behavioural data using a self-administered questionnaire. Urines and swabs were tested for Chlamydia trachomatis (Ct), Neisseria gonorrhoea (Ng), Trichomonas vaginalis (Tv) and human pap

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13

Begna, Kebede H., Naseema Gangat, Mithun V. Shah, et al. "Anthracycline Choices for Induction Chemotherapy Among 797 Consecutive Adult Patients with Acute Myeloid Leukemia: Daunorubicin-60 Vs Idarubicin-12 Vs Daunorubicin-90." Blood 138, Supplement 1 (2021): 1267. http://dx.doi.org/10.1182/blood-2021-147485.

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Abstract Objective : We describe the Mayo Clinic experience in 797 newly-diagnosed patients with acute myeloid leukemia (AML) serially treated with 7+3 induction chemotherapy that included 3 days of daunorubicin at a daily dose of 60 mg/m2 (dauno-60; n=239) or 90 mg/m2 (dauno-90; n=52), or idarubicin 12 mg/m2 (IDA-12; n=506). Our objective was to compare overall (OS) and relapse-free (RFS) survival outcome. Methods : Newly-diagnosed AML patients seen at our institution and received intensive induction chemotherapy were identified from the Mayo Clinic AML database. Treatment period spanned from

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14

Rivera Teran, V., M. Pérez Rodríguez, D. Alpizar-Rodriguez, et al. "AB1229 SAFETY OF BIOSIMILAR ETANERCEPT IN THE TREATMENT OF RHEUMATIC DISEASES: DATA FROM THE MEXICAN ADVERSE EVENTS REGISTRY (BIOBADAMEX)." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1905.1–1906. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3819.

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Background:Access to biosimilar drugs in Mexico started on 2014. Although biosimilar drugs safety has proved comparability to originator drugs on trials, information about its safety on real-life data is limited.Objectives:To compare safety in terms of adverse events of biosimilar etanercept (BEt) to originator etanercept (OEt) using information from the Mexican Adverse Events Registry (BIOBADAMEX).Methods:BIOBADAMEX is a Mexican cohort that collects the information of biologic and biosimilar drugs used in patients with rheumatic diseases in public and private practice since 2016. Patients enr

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15

Anbazhagan, Arivarasu N., Shubha Priyamvada, Anas Alakkam, et al. "Transcriptional modulation of SLC26A3 (DRA) by sphingosine-1-phosphate." American Journal of Physiology-Gastrointestinal and Liver Physiology 310, no. 11 (2016): G1028—G1035. http://dx.doi.org/10.1152/ajpgi.00308.2015.

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SLC26A3 or Downregulated in adenoma (DRA) is the major Cl−/HCO3− exchanger involved in electroneutral NaCl absorption in the mammalian intestine. Alterations in DRA function and expression have been implicated in diarrheal diseases associated with inflammation or infection. Therefore, agents that upregulate DRA activity may serve as potential antidiarrheals. In this regard, sphingosine-1-phosphate (S1P), a member of the bioactive sphingolipid family, has been shown to modulate various cellular processes including improvement of intestinal barrier function. However, the role of S1P in modulatin

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16

Nagler, Arnon, Vanderson Rocha, Myriam Labopin, et al. "Allogeneic Hematopoietic Stem-Cell Transplantation for Acute Myeloid Leukemia in Remission: Comparison of Intravenous Busulfan Plus Cyclophosphamide (Cy) Versus Total-Body Irradiation Plus Cy As Conditioning Regimen—A Report From the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation." Journal of Clinical Oncology 31, no. 28 (2013): 3549–56. http://dx.doi.org/10.1200/jco.2013.48.8114.

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Purpose Cyclophosphamide (Cy) combined with total-body irradiation (TBI) or with busulfan (Bu) are currently the most common myeloablative regimens used in allogeneic stem-cell transplantation (alloSCT) in adults with acute myelogenous leukemia (AML). Intravenous (IV) Bu has more predictable bioavailability and a safer toxicity profile than the oral formulation. Comparative studies of outcomes have been performed between oral Bu/Cy and Cy/TBI, but there have been no comparative trials in the era of IV Bu. Patients and Methods We performed a retrospective registry-based study comparing outcomes

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17

Chu, Patricia, Arya Patel, Vicki Helgeson, Andrea B. Goldschmidt, Mary Katherine Ray, and Mary Ellen Vajravelu. "Perception and Awareness of Diabetes Risk and Reported Risk-Reducing Behaviors in Adolescents." JAMA Network Open 6, no. 5 (2023): e2311466. http://dx.doi.org/10.1001/jamanetworkopen.2023.11466.

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ImportanceLifestyle change is central to diabetes risk reduction in youth with overweight or obesity. Feeling susceptible to a health threat can be motivational in adults.ObjectiveTo evaluate associations between diabetes risk perception and/or awareness and health behaviors in youth.Design, Setting, and ParticipantsThis cross-sectional study analyzed data from the US National Health and Nutrition Examination Survey 2011 to 2018. Participants included youths aged 12 to 17 years with body mass index (BMI) in the 85th percentile or higher without known diabetes. Analyses were conducted from Febr

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18

AYANKOSO, Micheal Taiwo, Damilola Miracle OLUWAGBAMILA, and Olugbenga Samson ABE. "EFFECTS OF ACTIVATED CHARCOAL ON LIVESTOCK PRODUCTION: A REVIEW." Slovak Journal of Animal Science 56, no. 01 (2023): 46–60. http://dx.doi.org/10.36547/sjas.791.

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Aerts, R. (1997). Nitrogen partitioning between resorption and decomposition pathways: a trade-off between nitrogen use efficiency and litter decomposability? Oikos, 80(3), 603−406. Ahmedna, M., Marshall, W. E. & Rao, R. O. (2000). Granular Activated Carbons from Agricultural By-Products: Preparation, Properties, and Application in Cane Sugar Refining. LSU AgCenter: Bulletin Number 869. Albiker, D. & Zweifel, R. (2019). Pflanzenkohle im Futter oder in der Einstreu und ihre Wirkung auf die Stickstoffretention und Leistung von Broilern. Wissenschaftstagung Ökologischer Landbau. Kassel: S

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19

Cooperberg, Matthew R., John Bihn, John Culnan, et al. "Can magnetic resonance imaging safely replace a confirmatory biopsy in patients on active surveillance for prostate cancer?" Journal of Clinical Oncology 43, no. 5_suppl (2025): 331. https://doi.org/10.1200/jco.2025.43.5_suppl.331.

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331 Background: Active surveillance (AS) is recognized as the preferred management for patients with low-risk prostate cancer, and many with favorable intermediate risk tumors as well. AS has been increasing in utilization both within the Veterans Affairs (VA) Healthcare System and nationally in the U.S. However, the limited data evaluating the quality of AS protocols suggests wide variability. One area of controversy is whether magnetic resonance imaging (MRI) can replace prostate biopsy to guide decisions about whether to remain on AS. We aimed to quantify the performance characteristics of

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20

Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics

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21

Patel, T. J., D. Cuizon, O. Mathieu-Costello, J. Fridén, and R. L. Lieber. "Increased oxidative capacity does not protect skeletal muscle fibers from eccentric contraction-induced injury." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 274, no. 5 (1998): R1300—R1308. http://dx.doi.org/10.1152/ajpregu.1998.274.5.r1300.

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Isometric electrical stimulation was delivered to rabbit dorsiflexor muscles at 10 Hz for 1 s on and 1 s off over 30 min, 5 days/wk for 3 wk to induce an increase in muscle oxidative capacity. Stimulation-trained muscles as well as untrained muscles were then subjected to a 30-min eccentric exercise bout to test whether increased oxidative capacity provided a protective effect against muscle injury. Electrical stimulation resulted in significant training of both the extensor digitorum longus (EDL) and tibialis anterior (TA) muscles, with EDL citrate synthase (CS) activity increasing an average

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22

Hamlin, Michael J., Will G. Hopkins, and Stephen C. Hollings. "Effects of Altitude on Performance of Elite Track-and-Field Athletes." International Journal of Sports Physiology and Performance 10, no. 7 (2015): 881–87. http://dx.doi.org/10.1123/ijspp.2014-0261.

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Purpose:Lower barometric air pressure at altitude can affect competitive performance of athletes in some sports. Reported here are the effects of various altitudes on elite track-and-field athletes’ performance.Methods:Lifetime track-and-field performances of athletes placed in the top 16 in at least 1 major international competition between 2000 and 2009 were downloaded from the database at tilastopaja.org. There were 132,104 performances of 1889 athletes at 794 venues. Performances were logtransformed and analyzed using a mixed linear model with fixed effects for 6 levels of altitude and ran

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Mikhaleva, Mariia, Svitlana Tyekucheva, Kiyomi Mashima, Stacey M. Fernandes, Matthew S. Davids, and Jennifer R. Brown. "Higher Mutational Burden Is an Independent Predictor of Shorter Time to First Treatment in Untreated Chronic Lymphocytic Leukemia Patients." Blood 142, Supplement 1 (2023): 3270. http://dx.doi.org/10.1182/blood-2023-173738.

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Background. Recent advancements in next-generation sequencing (NGS) technologies have revolutionized the ability to comprehensively profile chronic lymphocytic leukemia (CLL), unveiling various molecular lesions. Complex mutational landscapes and diverse combinatorial patterns of genetic alterations lead to heterogeneity of clinical course and outcomes. The primary objective of this study was to identify patterns of co-occurrence (CO) and mutual exclusivity (ME) among mutations in CLL and their impact on time to first treatment (TTFT). Methods. The cohort included 795 treatment-naïve (TN) pati

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Puthumana, Joseph S., Christopher D. Lopez, Alisa Girard, et al. "Evaluating YouTube Video Quality in Orthognathic Surgery Patient Education." FACE 3, no. 1 (2022): 80–86. http://dx.doi.org/10.1177/27325016211072899.

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Background: Patients are increasingly accessing consumer-style health information from a variety of web-based platforms. This study aims to assess a popular audio-visual platform for its quality of information in orthognathic procedures. Methods: We queried YouTube on August 12th, 2021 for 20 videos, by both relevance and view count, under each of 3 search terms: (1) “orthognathic surgery,” (2) “LeFort I osteotomy,” and (3) “sagittal split osteotomy.” Each video was characterized by date of upload, time since upload, video duration, video type, and video author. Videos were further characteriz

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Udalova, Victoria, Vinayak Bhatia, and Maria Polyakova. "Association of Family Income With Morbidity and Mortality Among US Lower-Income Children and Adolescents." JAMA 328, no. 24 (2022): 2422. http://dx.doi.org/10.1001/jama.2022.22778.

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ImportanceFamily income is known to be associated with children’s health; the association may be particularly pronounced among lower-income children in the US, who tend to have more limited access to health resources than their higher-income peers.ObjectiveTo investigate the association of family income with claims-based measures of morbidity and mortality among children and adolescents in lower-income families in the US enrolled in Medicaid or the Children’s Health Insurance Program.Design, Setting, and ParticipantsThis cross-sectional analysis included 795 000 participants aged 5 to 17 years

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Gomes, Tiago Halyson de Oliveira, Beatriz Pellizzon, Giovanna Victória Moura Araújo, et al. "MAMOPLASTIA PÓS BARIÁTRICA." Revista ft 29, no. 144 (2025): 02–03. https://doi.org/10.69849/revistaft/fa10202503150102.

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INTRODUÇÃO: A mamoplastia pós bariátrica é um procedimento cirúrgico realizado para remodelar as mamas de pacientes que passaram por cirurgia bariátrica, visando corrigir a flacidez e o excesso de pele resultantes da perda significativa de peso. Esse procedimento é indicado para melhorar a estética e a autoestima dos pacientes, após a redução substancial de peso corporal. OBJETIVOS: O objetivo do presente trabalho foi realizar o levantamento acerca dos procedimentos cirúrgicos de mamoplastia pós bariátrica no Brasil, entre o período de 2013 a 2024. METODOLOGIA: O presente estudo trata-se de um

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Sleptcov, I. V., R. A. Chernikov, K. Yu Novokshonov, et al. "Tension-free thyroidectomy with medial access to the recurrent largeal nerves and thyroid vessels: methodology, results of application, advantages and disadvantages." Clinical and experimental thyroidology 20, no. 2 (2024): 5–14. https://doi.org/10.14341/ket12793.

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BACKGROUND: Despite technical improvements in surgical equipment, a significant number of studies report a high incidence of recurrent laryngeal nerve paresis and hypoparathyroidism. In order to reduce specific complications, we have proposed an alternative method of performing thyroidectomy — tension-free thyroidectomy (TFT) with medial access to the recurrent laryngeal nerve (RLN) and parathyroid glands.AIM: Assessing the effectiveness and safety of the TFT method.MATERIALS AND METHODS: The study included patients who were treated at the Saint Petersburg State University Hospital in the peri

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Mashayekhi, Mona, Hui Nian, Sara E. Howard, et al. "LBSUN306 Effects Of Glp-1 Receptor Agonism, Dpp4 Inhibition, And Hypocaloric Diet On Metabolic Parameters In Obese Pre-diabetic Individuals: A Randomized-controlled Trial." Journal of the Endocrine Society 6, Supplement_1 (2022): A292—A293. http://dx.doi.org/10.1210/jendso/bvac150.603.

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Abstract Background GLP-1 receptor (GLP1R) agonists reduce glucose, weight and cardiovascular risk. Understanding the weight loss-dependent mechanisms of these benefits will inform treatment and drug development. This study compared metabolic responses among GLP1R agonist (liraglutide), DPP4 inhibitor (sitagliptin), and hypocaloric diet treatments. Methods We randomized 88 obese, pre-diabetic individuals in a 2: 1: 1 ratio to liraglutide, sitagliptin, or diet for 14 weeks. Treatment was double-blinded and placebo-controlled for drug. Individuals completed a mixed meal at baseline, 2 and 14 wee

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Khorrami, Zeinab, Maud Langlois, Paul C. Clark, et al. "High-contrast and resolution near-infrared photometry of the core of R136." Monthly Notices of the Royal Astronomical Society 503, no. 1 (2021): 292–311. http://dx.doi.org/10.1093/mnras/stab388.

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ABSTRACT We present the sharpest and deepest near-infrared photometric analysis of the core of R136, a newly formed massive star cluster at the centre of the 30 Doradus star-forming region in the Large Magellanic Cloud. We used the extreme adaptive optics of the SPHERE focal instrument implemented on the ESO Very Large Telescope and operated in its IRDIS imaging mode for the second time with longer exposure time in the H and K filters. Our aim was to (i) increase the number of resolved sources in the core of R136, and (ii) to compare with the first epoch to classify the properties of the detec

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Diklic, Aleksandar, Vladan Zivaljevic, Ivan Paunovic, Nevena Kalezic, and Svetislav Tatic. "Surgical procedures in patients with thyroid autoimmune disease." Srpski arhiv za celokupno lekarstvo 133, Suppl. 1 (2005): 77–83. http://dx.doi.org/10.2298/sarh05s1077d.

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Autoimmune thyroid disease is a serious medical problem in which various operative procedures are performed. The objective of the study is to explore the type of applied surgical procedures in autoimmune thyroid disease, advantages and disadvantages of various procedures, and criteria they have to meet. This is retrospective clinical study on 1478 patients, operated for Graves? toxic goiter (117 males and 795 females mean age 37.7) and Hashimoto thyroiditis (27 males and 539 females mean age 50.6) from 1995 to April 2005. Cancer in Graves? disease was found in 61 patients (6.7%), papillary in

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Stolovitzky, J. Pablo, Randall A. Ow, Stacey L. Silvers, Nadim B. Bikhazi, Curtis D. Johnson, and Masayoshi Takashima. "Effect of Radiofrequency Neurolysis on the Symptoms of Chronic Rhinitis: A Randomized Controlled Trial." OTO Open 5, no. 3 (2021): 2473974X2110411. http://dx.doi.org/10.1177/2473974x211041124.

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Objective To determine the safety and efficacy of temperature-controlled radiofrequency (RF) neurolysis of the posterior nasal nerve (PNN) area for the treatment of chronic rhinitis. Study Design A multicenter, prospective, single-blinded, randomized controlled trial, in which the control arm underwent a sham procedure. Setting Sixteen otolaryngology centers. Methods Patients with 24-hour reflective Total Nasal Symptom Score (rTNSS) ≥6, including moderate to severe rhinorrhea and mild to severe congestion, were randomized 2:1 to active treatment of the posterior nasal nerve area with a tempera

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Chen, Jennifer Hechao, Kerollos Wanis, Mahdia Rahman, et al. "Implications for sentinel lymph node biopsy (SLNB) omission in patients with early-stage node-negative HR+/HER2- breast cancer undergoing mastectomy." Journal of Clinical Oncology 43, no. 16_suppl (2025): 580. https://doi.org/10.1200/jco.2025.43.16_suppl.580.

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580 Background: The SOUND and INSEMA trials demonstrated non-inferiority of SLNB omission in HR+/HER2- early-stage breast cancer (BC) patients with negative axillary ultrasound (AUS) undergoing breast conserving therapy (BCT). However, it remains unclear if this approach may be applied to patients receiving mastectomy. We evaluated outcomes in a similar patient population receiving BCT versus mastectomy. Methods: Using an institutional database (2010-2023), we identified patients with cT1N0M0 HR+/HER2- unifocal invasive ductal carcinoma with negative AUS who underwent upfront BCT (breast conse

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Ohle, R., H. Kareemi, and J. J. Perry. "LO075: Clinical exam for acute aortic dissection: a systematic review and meta-analysis." CJEM 18, S1 (2016): S56. http://dx.doi.org/10.1017/cem.2016.112.

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Introduction: Acute aortic dissection (AAD) is difficult to diagnose and if missed carries a significant mortality rate. Our aim was to assess the accuracy of history, physical exam and plain radiographs compared to advanced imaging in the diagnosis of AAD in adults presenting to the ED with a clinical suspicion of AAD. Methods: We conducted a librarian assisted systematic review. Databases searched: Pubmed, Medline, Embase and the Cochrane database from 1968 to January 2016. No restrictions for language were imposed. Studies were reviewed and data extracted by two independent reviewers. AAD w

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Reis, Karoline Maso dos, Antônio Carlos Barreto, and José Renato Zanini. "VAZÃO E UNIFORMIDADE DE DISTRIBUIÇÃO DE TUBO GOTEJADOR EM SUPERFÍCIE E SUBSUPERFÍCIE." IRRIGA 22, no. 4 (2017): 690–700. http://dx.doi.org/10.15809/irriga.2017v22n4p690-700.

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VAZÃO E UNIFORMIDADE DE DISTRIBUIÇÃO DE TUBO GOTEJADOR EM SUPERFÍCIE E SUBSUPERFÍCIE*   KAROLINE MASO DOS REIS1; ANTÔNIO CARLOS BARRETO1 E JOSÉ RENATO ZANINI2  *Artigo extraído da dissertação da primeira autora 1Instituto Federal de Educação, Ciência e Tecnologia do Triângulo Mineiro, Rua João Batista Ribeiro, 4000 Distrito Industrial II 38064-790, Uberaba, Minas Gerais, Brasil. E-mails: karoline@iftm.edu.br; barreto@iftm.edu.br.  2Departamento de Engenharia Rural, Faculdade de Ciências Agrárias e Veterinárias (FCAV), Universidade Estadual Paulista (UN

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Moltó, A., A. Ajrouche, D. Tran, et al. "POS0305 CONTINUING TNFI AFTER PREGNANCY DIAGNOSIS IN WOMEN WITH CHRONIC RHEUMATIC INFLAMMATORY DISEASES IS NOT ASSOCIATED WITH WORSE OBSTETRICAL OR INFECTIOUS OUTCOMES: THE RESULTS OF AN EMULATED TARGET TRIAL." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 395.2–396. http://dx.doi.org/10.1136/annrheumdis-2023-eular.3787.

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BackgroundContinuation of biologics during pregnancy in patients with chronic inflammatory diseases during pregnancy is still a difficult medical decision. Many women with chronic rheumatic inflammatory diseases (CRID) decide to stop tumor necrosis factor inhibitors (TNFi) treatment once pregnancy is confirmed to avoid potential adverse fetal events but taking the risk of inflammatory flare.ObjectivesTo compare in real life settings the pregnancy outcomes of two treatment strategies among women with CRID: to continue TNFi vs. stop TNFi upon pregnancy diagnosis.Methodsthe French nationwide heal

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Haroon, Nigil, Irene van der Horst-Bruinsma, Matthew Brown, et al. "Low Uveitis Rates in Patients with Axial Spondyloarthritis or Psoriatic Arthritis Treated with Bimekizumab: Long-Term Results from Phase 2B/3 Trials." Journal of Rheumatology 52, Suppl 2 (2025): 84.1–84. https://doi.org/10.3899/jrheum.2025-0314.82.

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ObjectivesBimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F in addition to IL17A. Here, we report long-term incidence of acute anterior uveitis (uveitis’) following BKZ treatment in patients (pts) with axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA).MethodsSafety data are reported for 2 pools, each comprising 3 phase 2b/3 studies and their open-label extensions, in pts with active axSpA (non-radiographic and radiographic axSpA) and active PsA, respectively. Uveitis events were identified using the preferred terms “autoimmune uveitis,” “

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Kraft, Daniel L., and Irving L. Weissman. "Effect and Kinetics of Depleting ACK-2 Anti C-Kit Monoclonal Antibody on Hematopoeisis and Hematopoetic Progenitors and Ability To Condition for Bone Marrow Transplantation." Blood 104, no. 11 (2004): 4963. http://dx.doi.org/10.1182/blood.v104.11.4963.4963.

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Abstract c-kit is expressed on hematopoetic stem and progenitor cell populations. ACK-2 is an anti-mouse c-Kit monoclonal antibody which has been shown (by Nishikawa et al) to antagonize the function of c-kit and deplete the bone marrow of treated mice. We wished to characterize the effect of the anti c-kit mAb ACK-2 on the peripheral blood cell counts and marrow hematopoetic stem cell and progenitor populations. We also tested the hypothesis that treatment with ACK-2 may serve as a novel means of non-myeloablative conditioning for hematopoeitic stem cell transplantation. METHODS: Adult C57 bl

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Ferré, C., A. Leip, G. Matteucci, F. Previtali, and G. Seufert. "Impact of 40 years poplar cultivation on soil carbon stocks and greenhouse gas fluxes." Biogeosciences Discussions 2, no. 4 (2005): 897–931. http://dx.doi.org/10.5194/bgd-2-897-2005.

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Abstract. Within the JRC Kyoto Experiment in the Regional Park and UN-Biosphere Reserve "Parco Ticino" (North-Italy, near Pavia), the soil carbon stocks and fluxes of CO2, N2O, and CH4 were measured in a poplar plantation in comparison with a natural mesohygrophilous deciduous forest nearby, which represents the pristine land cover of the area. Soil fluxes were measured using the static and dynamic closed chamber techniques for CH4 N2O, and CO2, respectively. We made further a pedological study to relate the spatial variability found with soil parameters. Annual emission fluxes of N2O and CO2

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Cermak, Jaroslav, Dana Mikulenková, Jana Brezinova, and Kyra Michalova. "A reclassification of Myelodysplastic Syndrome (MDS) patients of RAEB-1 subgroup according to IPSS-R improves discrimination of high risk patients and better predicts overall Survival. A retrospective analysis of 49 Patients." Blood 120, no. 21 (2012): 4957. http://dx.doi.org/10.1182/blood.v120.21.4957.4957.

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Abstract Abstract 4957 Refractory anemia with excess of bone marrow (BM) blasts up to 10% (RAEB-1) has been generally considered a MDS subgroup with moderate prognosis and most of the patients are not indicated for immediate intensive treatment. In our retrospective study, 27 out of 49 patients with RAEB-1 had intermediate-1 (IM-1) risk and 22 patients were classified as intermediate-2 (IM-2) risk group according to the IPSS. Nevertheless, median survival of untreated patients with RAEB-1. was only 5. 0 months compared to 36. 3 months in untreated patients with ≤ 5% BM blasts at the time of di

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Fernández-Ortuño, D., P. K. Bryson, A. Grabke, and G. Schnabel. "First Report of Fludioxonil Resistance in Botrytis cinerea from a Strawberry Field in Virginia." Plant Disease 97, no. 6 (2013): 848. http://dx.doi.org/10.1094/pdis-01-13-0012-pdn.

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Gray mold caused by Botrytis cinerea Pers.:Fr. is one of the most economically important diseases of cultivated strawberry (Fragaria × ananassa) worldwide. Control of gray mold mainly depends on fungicides, including the phenylpyrrole fludioxonil, which is currently marketed in combination with cyprodinil as Switch 62.5WG (Syngenta Crop Protection, Research Triangle Park, Raleigh, NC). In 2012, 790 strains of B. cinerea were collected from 76 strawberry fields in eight states, including Arkansas, Florida, Georgia, Kansas, Maryland, North Carolina, South Carolina, and Virginia. Strains were col

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Alten, R., X. Mariette, R. M. Flipo, et al. "POS0447 PHYSICAL FUNCTION IN PATIENTS WITH RA, STRATIFIED BY SEROSTATUS AND TREATMENT LINE, FOLLOWING SC ABATACEPT: POST HOC ANALYSIS OF AN OBSERVATIONAL, 2-YEAR STUDY CONDUCTED IN ROUTINE CLINICAL PRACTICE (ASCORE)." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 453–54. http://dx.doi.org/10.1136/annrheumdis-2021-eular.903.

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Background:RA is characterised by the production of autoantibodies, including RF and anti-citrullinated protein antibodies (ACPAs).1 Seropositive disease is associated with poorer prognosis in patients with RA,2 and response to different treatments has been shown to vary based on ACPA status.3 ASCORE (Abatacept SubCutaneOus in Routine Clinical PracticE; NCT02090556) was a 2-year, observational, prospective, multicentre study of SC abatacept for the treatment of RA.4Objectives:This post hoc analysis of the ASCORE study evaluated patient-reported outcomes, assessed using HAQ-DI, by RF/ACPA seros

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Kattamis, C., Y. Kilinc, S. Fattoum, et al. "Deferasirox (Exjade®, ICL670) Demonstrates Iron Chelating Efficacy Related to Transfusional Iron Intake in Pediatric Patients." Blood 106, no. 11 (2005): 2692. http://dx.doi.org/10.1182/blood.v106.11.2692.2692.

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Abstract Chelation therapy is the conventional treatment for transfusional iron overload, which leads to complications in the heart, liver and endocrine glands. A 1-year, open-label, multicenter, Phase III study compared the investigational, once-daily, oral iron chelator deferasirox (DSX) with deferoxamine (DFO) in adult and pediatric β-thalassemia patients aged ≥ 2 years. Patients with liver iron concentration (LIC) of 2–3, &gt;3–7, &gt;7–14 and &gt;14 mg Fe/g dw were randomized to receive daily DSX 5, 10, 20 and 30 mg/kg or DFO 20–30, 25–35, 35–50 and ≥ 50 mg/kg, respectively. I

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Fiegl, Michael, Andreas Falkner, Michael Fidrik, et al. "Alemtuzumab in B-Cell Prolymphoytic Leukemia (B-PLL) and Richter’s Transformation." Blood 108, no. 11 (2006): 4733. http://dx.doi.org/10.1182/blood.v108.11.4733.4733.

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Abstract Alemtuzumab is the standard therapy for treatment of patients with relapsed/refractory B-CLL. Significant responses have also been documented in the front-line CLL setting, and as well as in first-line therapy of patients with T-PLL, a population with an exceptionally poor prognosis and few available therapeutic options. Limited data available on the therapeutic benefit of alemtuzumab in other aggressive lymphomas such as B-PLL, which is rare, with a heterogeneous clinical course, and often chemoresistant, as well as CLL with Richter’s transformation, which is also characterized by a

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MacMillan, Margaret L., Marie Robin, Andrew C. Harris, et al. "A Refined Clinical Risk Score at Onset of Treatment for Acute Gvhd That Predicts Response to Initial Therapy, Survival and Transplant-Related Mortality." Blood 124, no. 21 (2014): 188. http://dx.doi.org/10.1182/blood.v124.21.188.188.

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Abstract Corticosteroids are the standard initial therapy for acute graft-versus-host disease (aGVHD) but are effective in only half of the cases. Methods to identify patients who are unlikely to respond to conventional initial therapy and who warrant alternative, more effective initial therapy are needed. The Minnesota (MN) group recently defined high-risk (HR)-aGVHD at onset by a novel acute GVHD risk score (Br J Haem 157(6):732,2012). Patients with HR-aGVHD were less likely to respond to steroid therapy and had a 2-fold increased risk of treatment-related (non-relapse) mortality (TRM) compa

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Remy, Katya, Chase Alston, Elyse Gonzales, et al. "Targeted Reinnervation During Gender-Affirming Mastectomy and Restoration of Sensation." JAMA Network Open 7, no. 11 (2024): e2446782. http://dx.doi.org/10.1001/jamanetworkopen.2024.46782.

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ImportanceDuring gender-affirming mastectomy, nerves are transected, resulting in sensory loss. Nerve preservation using targeted nipple-areola complex (NAC) reinnervation (TNR) may restore sensation.ObjectiveTo determine the quantitative and patient-reported sensory outcomes of TNR.Design, Setting, and ParticipantsProspective matched cohort study of patients undergoing gender-affirming mastectomy from August 2021 to December 2022 at Weill Cornell Medicine and Massachusetts General Hospital. Data were analyzed from January to March 2023.ExposurePatients who underwent TNR and matched patients w

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Wu, Bei, Guowen Yin, Xu He, et al. "Endovascular Treatment of Cancer-Associated Venous Obstruction: Comparison of Efficacy Between Stent Alone and Stent Combined With Linear Radioactive Seeds Strand." Vascular and Endovascular Surgery 54, no. 7 (2020): 565–72. http://dx.doi.org/10.1177/1538574420939747.

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Objectives: To investigate the safety and efficacy of a stent combined with a linear strand of 125I seeds to treat malignant cancer–associated venous obstruction. Methods: We retrospectively analyzed the data of 57 patients with malignant cancer–associated venous obstruction. Nineteen patients underwent the placement of a stent combined with a linear strand of 125I seeds (group A), and 38 patients underwent the placement of a bare stent (group B). The following parameters were compared between the 2 groups of patients: symptom relief rate, duration of venous patency, survival time, quality of

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Mamlouk, Omar, Anastasia Turin, David D'Achiardi, et al. "Clinical characteristics and outcomes of cancer patients with chronic kidney disease and coronavirus disease 2019." Journal of Clinical Oncology 39, no. 15_suppl (2021): e18815-e18815. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e18815.

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e18815 Background: Coronavirus disease 2019 (COVID-19) has been associated with higher risk of acute kidney injury (AKI) and mortality rate in cancer patients. The prevalence of CKD in cancer patients is close to 20-30% however there has been limited data about cancer patients with CKD and COVID-19 infection. The aim of this study is to evaluate the clinical characteristics and outcomes of this patient population at a tertiary cancer center. Methods: All patient data — demographics, labs, comorbidities and outcomes — were aggregated and analyzed in the Syntropy platform, Palantir Foundry (“Fou

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Pérez-Stable, Eliseo J., Asmi Panigrahi, Saida I. Coreas, et al. "Diabetes and Hypertension Risk Across Acculturation and Education Levels in Hispanic/Latino Adults." JAMA Health Forum 6, no. 3 (2025): e250273. https://doi.org/10.1001/jamahealthforum.2025.0273.

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ImportanceAcculturation among Hispanic/Latino populations, defined as adaptation to US lifestyle and culture, is often assumed to lead to adverse health outcomes that will reduce the immigrant health advantage.ObjectiveTo evaluate the risks for incident diabetes and hypertension by levels of acculturation and educational attainment.Design, Setting, and ParticipantsThis study used data from the Hispanic Community Health Study/Study of Latinos, a population-based cohort study of men and women aged 18 to 74 years who identified as Central American, Cuban, Dominican, Mexican, Puerto Rican, or Sout

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Casais, Patricia. "Seven-Year Follow up of An Inception Cohort Study of Patients with Atrial Fibrillation Starting Oral Anticoagulation: Aging as An Independent Bleeding Risk." Blood 112, no. 11 (2008): 4045. http://dx.doi.org/10.1182/blood.v112.11.4045.4045.

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Abstract Introduction: Our objectives were to investigate if aging is an independent risk factor for major bleeding during oral anticoagulant treatment (OAT) for atrial fibrillation (AF). Patients and Methods: An inception cohort study was designed to include patients (pts) referred to our Department to initiate OAT due to AF from July 2000 to July 2007. Inclusion criteria: no prior OAT, AF being the only reason to OAT, follow-up at our Institution, and signed informed consent. Exclusion criteria: concomitant reason for OAT, and pts refusal to participate. Pts were followed until OAT was stopp

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Karisani, Negin, Amit Sud, Liang Li, et al. "The Impact of Therapeutic Selective Pressure on the Evolutionary Landscape of Chronic Lymphocytic Leukemia." Blood 144, Supplement 1 (2024): 3233. https://doi.org/10.1182/blood-2024-199916.

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BACKGROUND Our knowledge of how the genomic landscape of chronic lymphocytic leukemia (CLL) is impacted by the selective pressure imposed by chemotherapy and targeted agents remains incomplete. We hypothesize that the extent of clonal evolution, baseline transcriptional state, and the overall and clone-specific growth kinetics of CLL will vary under native conditions or following exposure to chemotherapy and targeted therapy. METHODS We report the systematic genomic analysis of leukemia-normal whole-exome sequencing (WES) of 420 samples collected from 170 patients who were &gt;65 years of

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