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Статті в журналах з теми "Adhesive plaque":
1
George, Matthew N., Benjamin Pedigo, and Emily Carrington. "Hypoxia weakens mussel attachment by interrupting DOPA cross-linking during adhesive plaque curing." Journal of The Royal Society Interface 15, no. 147 (October 2018): 20180489. http://dx.doi.org/10.1098/rsif.2018.0489.
Анотація:
Marine mussels ( Mytilus spp.) attach to a wide variety of surfaces underwater using a network of byssal threads, each tipped with a protein-based adhesive plaque that uses the surrounding seawater environment as a curing agent. Plaques undergo environmental post-processing, requiring a basic seawater pH be maintained for up to 8 days for the adhesive to strengthen completely. Given the sensitivity of plaques to local pH conditions long after deposition, we investigated the effect of other aspects of the seawater environment that are known to vary in nearshore habitats on plaque curing. The effect of seawater temperature, salinity and dissolved oxygen concentration were investigated using tensile testing, atomic force microscopy and amino acid compositional analysis. High temperature (30°C) and hyposalinity (1 PSU) had no effect on adhesion strength, while incubation in hypoxia (0.9 mg l −1 ) caused plaques to have a mottled coloration and prematurely peel from substrates, leading to a 51% decrease in adhesion strength. AFM imaging of the plaque cuticle found that plaques cured in hypoxia had regions of lower stiffness throughout, indicative of reductions in DOPA cross-linking between adhesive proteins. A better understanding of the dynamics of plaque curing could aid in the design of better synthetic adhesives, particularly in medicine where adhesion must take place within wet body cavities.
2
Filippidi, Emmanouela, Daniel G. DeMartini, Paula Malo de Molina, Eric W. Danner, Juntae Kim, Matthew E. Helgeson, J. Herbert Waite, and Megan T. Valentine. "The microscopic network structure of mussel ( Mytilus ) adhesive plaques." Journal of The Royal Society Interface 12, no. 113 (December 2015): 20150827. http://dx.doi.org/10.1098/rsif.2015.0827.
Анотація:
Marine mussels of the genus Mytilus live in the hostile intertidal zone, attached to rocks, bio-fouled surfaces and each other via collagen-rich threads ending in adhesive pads, the plaques. Plaques adhere in salty, alkaline seawater, withstanding waves and tidal currents. Each plaque requires a force of several newtons to detach. Although the molecular composition of the plaques has been well studied, a complete understanding of supra-molecular plaque architecture and its role in maintaining adhesive strength remains elusive. Here, electron microscopy and neutron scattering studies of plaques harvested from Mytilus californianus and Mytilus galloprovincialis reveal a complex network structure reminiscent of structural foams. Two characteristic length scales are observed characterizing a dense meshwork (approx. 100 nm) with large interpenetrating pores (approx. 1 µm). The network withstands chemical denaturation, indicating significant cross-linking. Plaques formed at lower temperatures have finer network struts, from which we hypothesize a kinetically controlled formation mechanism. When mussels are induced to create plaques, the resulting structure lacks a well-defined network architecture, showcasing the importance of processing over self-assembly. Together, these new data provide essential insight into plaque structure and formation and set the foundation to understand the role of plaque structure in stress distribution and toughening in natural and biomimetic materials.
3
Suroliya, Kritika Pankaj, Priyanka Niranjane, Ranjit Haridas Kamble, Murtaza Shabbir Hussain, Saurabh Hemant Shingnapurkar, Pallavi Sachin Daigavane, and Zoher Esmail Merchant. "Comparative Evaluation of Effect of Excessive Adhesive Flash Formed from Two Orthodontic Adhesives on Clinical Periodontal Status of Patients Undergoing Fixed Orthodontic Appliance Therapy." Journal of Evolution of Medical and Dental Sciences 10, no. 32 (August 2021): 2582–86. http://dx.doi.org/10.14260/jemds/2021/529.
Анотація:
BACKGROUND Increased accumulation of dental plaque and inflammatory response during treatment is due to the appearance of new retentive places around the components of fixed appliances attached to the teeth. During bonding procedures, there is certain amount of adhesive left on the tooth surface invariably around the margins between bracket and enamel interface called excessive adhesive flash (EAF), which may act as a plaque retentive area. We wanted to evaluate and compare the effect of EAF formed from two different orthodontic bonding adhesives on clinical periodontal status of patients undergoing fixed orthodontic appliance therapy. METHODS 20 patients indicated for treatment with fixed stainless steel preadjusted edgewise appliance were selected for the study. A split mouth design was followed where each patient’s teeth were divided into 2 groups; Group A: Teeth of right side bonded with non-tooth coloured orthodontic adhesive resin (Transbond XT Plus) – 1st and 4th quadrants; Group B: Teeth of left side bonded with tooth-coloured orthodontic adhesive resin (Transbond XT) - 2nd and 3rd quadrants. Clinical periodontal status was assessed by measuring Muhlemann modified papillary bleeding index, Turesky Gilmore Glickman modification of Quigley Hein Plaque Index, and a modification of the Orthodontic Plaque Index, before bonding (T0) and 1 week after bonding the appliance (T1). RESULTS Readings at T1 had significantly increased compared to T0 indicating increased plaque retention. However, difference between the indices for both groups at T1 was not statistically significant. CONCLUSIONS The excessive adhesive flash is a site for increased plaque accumulation, irrespective of the composite being tooth coloured or non-tooth coloured. KEY WORDS EAF, Adhesives, Split Mouth
4
Valois, Eric, Razieh Mirshafian, and J. Herbert Waite. "Phase-dependent redox insulation in mussel adhesion." Science Advances 6, no. 23 (June 2020): eaaz6486. http://dx.doi.org/10.1126/sciadv.aaz6486.
Анотація:
Catecholic 3,4-dihydroxyphenyl-l-alanine (Dopa) residues in mussel foot proteins (mfps) contribute critically to mussel (Mytilus californianus) plaque adhesion, but only if protected from oxidation at the adhesive-substratum interface. Dopa oxidation is thermodynamically favorable in seawater yet barely detectable in plaques; therefore, we investigated how plaques insulate Dopa-containing mfps against oxidation. Seawater sulfate triggers an mfp3 and mfp6 liquid-liquid phase separation (LLPS). By combining plaque cyclic voltammetry with electrophoresis, mass spectrometry, and redox-exchange chemistry, we show that Dopa-containing mfp3 and mfp6 in phase-separated droplets remain stable despite rapid oxidation in the surrounding equilibrium solution. The results suggest that a cohort of oxidation-prone proteins is endowed with phase-dependent redox stability. Moreover, in forming LLPS compartments, Dopa proteins become reservoirs of chemical energy.
5
Martinez Rodriguez, Nadine R., Saurabh Das, Yair Kaufman, Jacob N. Israelachvili, and J. Herbert Waite. "Interfacial pH during mussel adhesive plaque formation." Biofouling 31, no. 2 (February 2015): 221–27. http://dx.doi.org/10.1080/08927014.2015.1026337.
6
Cohen, Noy, J. Herbert Waite, Robert M. McMeeking, and Megan T. Valentine. "Force distribution and multiscale mechanics in the mussel byssus." Philosophical Transactions of the Royal Society B: Biological Sciences 374, no. 1784 (September 2019): 20190202. http://dx.doi.org/10.1098/rstb.2019.0202.
Анотація:
The byssi of sessile mussels have the extraordinary ability to adhere to various surfaces and withstand static and dynamic loadings arising from hostile environmental conditions. Many investigations aimed at understanding the unique properties of byssal thread–plaque structures have been conducted and have inspired the enhancement of fibre coatings and adhesives. However, a systems-level analysis of the mechanical performance of the composite materials is lacking. In this work, we discuss the anatomy of the byssus and the function of each of the three components (the proximal thread portion, the distal thread portion and the adhesive plaque) of its structures. We introduce a basic nonlinear system of springs that describes the contribution of each component to the overall mechanical response and use this model to approximate the elastic modulus of the distal thread portion as well as the plaque, the response of which cannot be isolated through experiment alone. We conclude with a discussion of unresolved questions, highlighting areas of opportunity where additional experimental and theoretical work is needed. This article is part of the theme issue ‘Transdisciplinary approaches to the study of adhesion and adhesives in biological systems’.
7
Wolff, Jonas O., and Marie E. Herberstein. "Three-dimensional printing spiders: back-and-forth glue application yields silk anchorages with high pull-off resistance under varying loading situations." Journal of The Royal Society Interface 14, no. 127 (February 2017): 20160783. http://dx.doi.org/10.1098/rsif.2016.0783.
Анотація:
The anchorage of structures is a crucial element of construction, both for humans and animals. Spiders use adhesive plaques to attach silk threads to substrates. Both biological and artificial adhesive structures usually have an optimal loading angle, and are prone to varying loading situations. Silk anchorages, however, must cope with loading in highly variable directions. Here we show that the detachment forces of thread anchorages of orb-web spiders are highly robust against pulling in different directions. This is gained by a two-step back-and-forth spinning pattern during the rapid production of the adhesive plaque, which shifts the thread insertion point towards the plaque centre and forms a flexible tree root-like network of branching fibres around the loading point. Using a morphometric approach and a tape-and-thread model we show that neither area, nor width of the plaque, but the shift of the loading point towards the plaque centre has the highest effect on pull-off resistance. This is explained by a circular propagation of the delamination crack with a low peeling angle. We further show that silken attachment discs are highly directional and adjusted to provide maximal performance in the upstream dragline. These results show that the way the glue is applied, crucially enhances the toughness of the anchorage without the need of additional material intake. This work is a starting point to study the evolution of tough and universal thread anchorages among spiders, and to develop bioinspired ‘instant’ anchorages of thread- and cable-like structures to a broad bandwidth of substrates.
8
Miller, Dusty R., Jamie E. Spahn, and J. Herbert Waite. "The staying power of adhesion-associated antioxidant activity in Mytilus californianus." Journal of The Royal Society Interface 12, no. 111 (October 2015): 20150614. http://dx.doi.org/10.1098/rsif.2015.0614.
Анотація:
The California mussel, Mytilus californianus , adheres in the highly oxidizing intertidal zone with a fibrous holdfast called the byssus using 3, 4-dihydroxyphenyl- l -alanine (DOPA)-containing adhesive proteins. DOPA is susceptible to oxidation in seawater and, upon oxidation, loses adhesion. Successful mussel adhesion thus depends critically on controlling oxidation and reduction. To explore how mussels regulate redox during their functional adhesive lifetime, we tracked extractable protein concentration, DOPA content and antioxidant activity in byssal plaques over time. In seawater, DOPA content and antioxidant activity in the byssus persisted much longer than expected—50% of extractable DOPA and 30% of extractable antioxidant activity remained after 20 days. Antioxidant activity was located at the plaque–substrate interface, demonstrating that antioxidant activity keeps DOPA reduced for durable and dynamic adhesion. We also correlated antioxidant activity to cysteine and DOPA side chains of mussel foot proteins (mfps), suggesting that mussels use both cysteine and DOPA redox reservoirs for controlling interfacial chemistry. These data are discussed in the context of the biomaterial structure and properties of the marine mussel byssus.
9
Greenwood, Jeffrey A., Anne B. Theibert, Glenn D. Prestwich, and Joanne E. Murphy-Ullrich. "Restructuring of Focal Adhesion Plaques by Pi 3-Kinase." Journal of Cell Biology 150, no. 3 (August 2000): 627–42. http://dx.doi.org/10.1083/jcb.150.3.627.
Анотація:
Focal adhesions are an elaborate network of interconnecting proteins linking actin stress fibers to the extracellular matrix substrate. Modulation of the focal adhesion plaque provides a mechanism for the regulation of cellular adhesive strength. Using interference reflection microscopy, we found that activation of phosphoinositide 3-kinase (PI 3-kinase) by PDGF induces the dissipation of focal adhesions. Loss of this close apposition between the cell membrane and the extracellular matrix coincided with a redistribution of α-actinin and vinculin from the focal adhesion complex to the Triton X-100–soluble fraction. In contrast, talin and paxillin remained localized to focal adhesions, suggesting that activation of PI 3-kinase induced a restructuring of the plaque rather than complete dispersion. Furthermore, phosphatidylinositol (3,4,5)-trisphosphate (PtdIns (3,4,5)-P3), a lipid product of PI 3-kinase, was sufficient to induce restructuring of the focal adhesion plaque. We also found that PtdIns (3,4,5)-P3 binds to α-actinin in PDGF-treated cells. Further evidence demonstrated that activation of PI 3-kinase by PDGF induced a decrease in the association of α-actinin with the integrin β subunit, and that PtdIns (3,4,5)-P3 could disrupt this interaction in vitro. Modification of focal adhesion structure by PI 3-kinase and its lipid product, PtdIns (3,4,5)-P3, has important implications for the regulation of cellular adhesive strength and motility.
10
Tilbury, Maura A., Sean McCarthy, Magdalena Domagalska, Thomas Ederth, Anne Marie Power, and J. Gerard Wall. "The expression and characterization of recombinant cp19k barnacle cement protein from Pollicipes pollicipes." Philosophical Transactions of the Royal Society B: Biological Sciences 374, no. 1784 (September 2019): 20190205. http://dx.doi.org/10.1098/rstb.2019.0205.
Анотація:
Adhesive proteins of barnacle cement have potential as environmentally friendly adhesives owing to their ability to adhere to various substrates in aqueous environments. By understanding the taxonomic breath of barnacles with different lifestyles, we may uncover commonalities in adhesives produced by these specialized organisms. The 19 kDa cement protein (cp19k) of the stalked barnacle Pollicipes pollicipes was expressed in Escherichia coli BL21 to investigate its adhesive properties. Initial expression of hexahistidine-tagged protein (rPpolcp19k-his) yielded low levels of insoluble protein. Co-overproduction of E. coli molecular chaperones GroEL-GroES and trigger factor (TF) increased soluble protein yields, although TF co-purified with the target protein (TF-rPpolcp19k-his). Surface coat analysis revealed high levels of adsorption of the TF-rPpolcp19k-his complex and of purified E. coli TF on both hydrophobic and hydrophilic surfaces, while low levels of adsorption were observed for rPpolcp19k-his. Tag-free rPpolcp19k protein also exhibited low adsorption compared to fibrinogen and Cell-Tak controls on hydrophobic, neutral hydrophilic and charged self-assembled monolayers under surface plasmon resonance assay conditions designed to mimic the barnacle cement gland or seawater. Because rPpolcp19k protein displays low adhesive capability, this protein is suggested to confer the ability to self-assemble into a plaque within the barnacle cement complex. This article is part of the theme issue ‘Transdisciplinary approaches to the study of adhesion and adhesives in biological systems’.
Дисертації з теми "Adhesive plaque":
1
Navarro, Etienne. "Dynamique de l'assemblage de wafers par adhésion moléculaire." PhD thesis, Université de Grenoble, 2014. http://tel.archives-ouvertes.fr/tel-01048574.
Анотація:
Lors de l'assemblage de wafers par adhésion moléculaire, un mince film d'air est piégé entre les deux wafers, créant ainsi un système fluide/structure couplé. La qualité finale de l'assemblage dépend fortement de la dynamique de ce système. L'initiation et la propagation du collage ont été étudiées, en régime transitoire, en utilisant un modèle de plaques minces couplée avec l'équation de Reynolds. La résolution numérique de l'équation, ainsi que la mesure optique du déplacement vertical de la plaquette durant le collage, nous a permis de valider le modèle et de mieux comprendre la dynamique du collage. Dans la continuité de cette étude, nous avons proposé une expression analytique de la courbure finale de l'assemblage en fonction des forces en jeu pendant le collage, ceci en utilisant à nouveau la théorie des plaques minces et en considérant l'existence d'un saut de déformation transverse le long de l'interface collée. Ce modèle a été validé par une expérience, impliquant le collage de wafers d'épaisseur différentes et en prenant soin de contrôler l'ensemble des forces agissant sur ces wafers. Nous observons une influence importante du film d'air sur la forme finale des wafers. En complément, un modèle du travail d'adhésion a été développé prenant en compte, à la fois, la rugosité d'interface et la quantité d'eau adsorbée. La différence de répartition de l'eau à l'interface de collage, nous permet d'expliquer les résultats expérimentaux montrant des valeurs d'énergie de séparation supérieure à celle de l'adhésion. Enfin, nous proposons une nouvelle méthode de mesure du travail d'adhésion pour la géométrie entière des wafers, utilisant la mesure de la taille d'une bulle cylindrique intentionnellement créée, par un petit objet, à l'interface de collage.
2
Forsgren, Nina. "Structural studies of the surface adhesin SspB from Streptococcus gordonii." Doctoral thesis, comprehensive summary, Umeå : Umeå universitet, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-32910.
3
Miguez, Andrés. "Positional control of oligodendrocyte development : Role of hox homeoproteins and Tag-1 cell adhesion molecule." Paris 6, 2010. http://www.theses.fr/2010PA066309.
Анотація:
Les oligodendrocytes sont les cellules myélinisantes du système nerveux central. La gaine de myéline ainsi que l’oligodendrocyte qui la synthétise, sont les cibles du processus pathologique dans la Sclérose En Plaques (SEP), une maladie neurologique autoimmune et démyélinisante du système nerveux central. Les progrès thérapeutiques des 10-15 dernières années ont permis une meilleure prise en charge de la composante autoimmune de la maladie. En revanche nous sommes toujours aussi démuni pour corriger la composante démyélinisante, qui pourtant est la cause du handicap sensori-moteur permanent. Dans le but de mettre en place des thérapies de réparation myélinique chez les patients atteints de SEP, des efforts sont développés pour identifier des cibles thérapeutiques qui permettraient de contrôler la production et la dispersion des cellules précurseurs d’oligodendrocytes (OPCs) dans la moelle épinière et le cerveau. Le développement embryonnaire et néonatal constitue une période privilégiée pour examiner ces phénomènes. Dans ce contexte, mon travail de thèse a porté sur l’identification de nouvelles molécules contrôlant la spécification régionale et la migration des OPCs ainsi que leur interaction avec les axones dans le système nerveux central en développement chez la souris. Une première contribution, portant sur l’étude de la molécule d’adhésion TAG-1, m’a permis de montrer que TAG-1 régule la structure de la myéline et des axones dans le nerf optique de souris. Dans un deuxième temps, j’ai exploré l’origine des oligodendrocytes dans le tronc cérébral de souris, et mon travail m’a permis de montrer que le facteur de transcription Hoxa2 réprime l’oligodendrogenèse.
4
Cournu-Rebeix, Isabelle. "Génétique de la sclérose en plaques : criblage anonyme du génome et gènes candidats." Paris 6, 2003. http://www.theses.fr/2003PA066074.
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Favre, Benoit. "Crushing properties of hexagonal adhesively bonded honeycombs loaded in their tubular direction." Thesis, Atlanta, Ga. : Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/22620.
Анотація:
Thesis (M. S.)--Civil and Environmental Engineering, Georgia Institute of Technology, 2007.Committee Chair: Mulalo Doyoyo; Committee Co-Chair: Reginald Desroches; Committee Member: Laurence J. Jacobs.
6
Moshaei, Mohammad Hossein. "Adhesion of Rolling Cell to Deformable Substrates in Shear Flow." Text, Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou153373230467728.
7
Mendonça, Rafaela Silva. "O papel da insularina, uma disintegrina recombinante (GST-INS), em processos de progressão tumoral: estudos in vitro." PublishedVersion, Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-12092016-104116/.
Анотація:
Plaquetas e células tumorais interagem em uma reação cruzada com proteínas do plasma, via integrina αIIbβ3 e αvβ3, respectivamente. A integrina αvβ3 também encontra-se presente na angiogênese tumoral. O objetivo desse trabalho foi avaliar a GST-INS, uma disintegrina recombinante do veneno de Bothrops insularis em eventos da progressão tumoral. Em condições estáticas, GST-INS foi capaz de inibir totalmente a adesão de células HUVECs e SK-MEL-28 às plaquetas em comparação ao controle e ao Aggrastat® (inibidor seletivo da integrina αIIbβ3). Além de inibir a TCIPA (agregação plaquetária induzida por células tumorais) a GST-INS também inibiu a invasão de SK-MEL-28 em substrato de matrigel. Células t.End.1 ou SK-MEL-28 pré-incubadas com GST-INS não formaram túbulos no substrato de matrigel. Análise por microscopia confocal mostrou que GST-INS liga-se a integrina αv presente nas células SK-MEL-28. Nossos resultados sugerem que essa disintegrina pode ser utilizada como potencial ferramenta no estudo e desenvolvimento de antiangiogênicos e antimetastáticos.Platelets and tumor cells interact in a cross-react with plasma proteins via integrin αIIbβ3 and αvβ3 , respectively.The integrin αvβ3 is also strongly stimulated in tumor angiogenesis. The aim of this study was to evaluate the ability of GST-INS, a recombinant disintegrin from Bothrops insularis venom on events of tumor progression. Under static conditions, GST-INS was able to completely inhibit the adhesion of endothelial cells (HUVECs) and melanoma cells (SK-MEL-28) to platelets compared to control and Aggrastat® (selective inhibitor of integrin αIIbβ3). In addition, GST-INS inhibit TCIPA (platelet aggregation induced by tumor cells) GST-INS also inhibited SK-MEL-28 on matrigel invasion substrate. t.End.1 cells or SK-MEL-28 pre-incubated with GST-INS were not able to form tubules in matrigel substrate. Analysis by confocal microscopy showed that GST-INS binds to integrin αv present in SK-MEL-28 cells. The results suggest that disintegrin can be used as a potential tool in the study and development of antiangiogenic and antimetastatic.
8
SILVA, Gilmar Correia. "Qualidade de pain?is aglomerados produzidos com adesivos ? base de lignosulfonato e ur?ia-formalde?do." PublishedVersion, Universidade Federal Rural do Rio de Janeiro, 2015. https://tede.ufrrj.br/jspui/handle/jspui/1505.
Анотація:
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CAPES
This study aimed to evaluate the quality of panels Pinus caribaea var caribaea produced from lignosulfonato based adhesive (LS), urea formaldehyde (UF) and mixtures thereof, variations in time and pressing temperature. For that, were determined the physical and chemical properties of wood and adhesives, the chemical composition of the LS and its chemical bonds by infrared spectroscopy (IR) and nuclear magnetic resonance (NMR), and pure in composition with different catalysts , the substitution effect of different percentages of UF by LS in the production of panels on the technological properties. They were also produced panels with modified LS acid. The predetermined nominal density of the panels was 0,70g/cm?. LS used in solid form was diluted to 45% in distilled water. The production of the panels was performed in three steps by varying the press temperature (140, 160 and 180?C). In the first step was applied at 140?C for composite panels 100% UF and thereafter was to be replaced by LS in the proportions of 20, 40, 60, 80 and 100%. In a second step, the first step three treatments with results from inferior mechanical properties were tested at temperatures of 160 to 180?C. In the third stage they were produced composite panels only with LS adhesive and acid in the previous three temperatures. The results of basic and apparent wood density were 0,54 and 0,60g/cm?, respectively. The extractive content of the wood was 1,80%, the macromolecular components present in the cell wall of the wood (cellulose, hemicellulose and lignin) followed the standard for the species, and pH and buffering capacity of the timber. NMR analysis showed the same pattern for lignin derivatives in their chemical bonds. Regarding the physical properties of the boards produced at 140?C, smaller percentages of thickness swelling and water absorption were checked in particleboards produced with 100% UF. For mechanical properties, no significant difference occurred between the panels made with 100% UF panels and modified with up to 40% LS. The panels produced with temperatures of 160 and 180?C generate similar results and in most higher in temperature at 180?C. Since the panels produced with LS and acid had generally improved in all properties, especially those with higher temperature
O presente trabalho teve como objetivo geral avaliar a qualidade de pain?is aglomerados de Pinus caribaea var. caribaea produzidos a partir de adesivo ? base de lignosulfonato (LS), ureia-formalde?do (UF) e suas misturas, sob varia??es de tempo e temperatura de prensagem. Para tanto, foram determinadas as propriedades f?sicas e qu?micas da madeira e dos adesivos, a composi??o qu?mica elementar do LS e suas liga??es qu?micas por meio da espectroscopia de infravermelho (IV) e resson?ncia magn?tica nuclear (RMN), puro e em composi??o com diferentes catalisadores, o efeito da substitui??o de diferentes porcentagens de UF por LS na produ??o dos pain?is sobre as propriedades tecnol?gicas. Tamb?m foram produzidos pain?is com LS modificados com ?cido. A densidade nominal preestabelecida dos pain?is foi de 0.70 g/cm?. O LS utilizado na forma s?lida foi dilu?do a 45% em ?gua destilada. A produ??o dos pain?is foi realizada em tr?s etapas variando a temperatura de prensagem (140, 160 e 180?C). Na primeira etapa foi aplicada a temperatura de 140?C para pain?is compostos com 100% de UF e a partir da? houve a sua substitui??o por LS nas propor??es de 20, 40, 60, 80 e 100%. Numa segunda etapa, tr?s tratamentos da primeira etapa com resultados de propriedades mec?nicas inferiores foram testados nas temperaturas de 160 e 180?C. Na terceira etapa foram produzidos pain?is compostos apenas com o adesivo LS e ?cido nas tr?s temperaturas anteriores. Os resultados da densidade b?sica e aparente da madeira foram de 0,54 e 0,60g/cm?, respectivamente. O teor de extrativos da madeira foi de 1,80%, os componentes macromoleculares presentes na parede celular da madeira (celulose, hemicelulose e lignina) seguiram o padr?o para a esp?cie, assim como o pH e a capacidade tamp?o da madeira. A an?lise de RMN mostrou o mesmo padr?o para derivados de lignina em suas liga??es qu?micas. Em rela??o ?s propriedades f?sicas dos pain?is produzidos a 140?C foram verificadas porcentagens menores de inchamento em espessura e absor??o de ?gua nos pain?is produzidos com 100% de UF. Para as propriedades mec?nicas, os tratamentos que tiveram composi??o modificada com at? 40% de LS, n?o apresentaram diferen?a significativa com o tratamento produzido com 100% de UF. Os pain?is produzidos com temperaturas de 160 e 180?C geraram resultados similares e na maioria superiores na temperatura de 180?C. J? os pain?is produzidos com LS e ?cido apresentaram em geral, melhoria em todas as propriedades, com destaque para aqueles com maior temperatura.
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Mallet, Daniel Gordon. "Mathematical Modelling of the Role of Haptotaxis in Tumour Growth and Invasion." Queensland University of Technology, 2004. http://eprints.qut.edu.au/15941/.
Анотація:
In this thesis, a number of mathematical models of haptotactic cell migration are developed. The modelling of haptotaxis is presented in two distinct parts - the first comprises an investigation of haptotaxis in pre-necrotic avascular tumours, while the second consists of the modelling of adhesion-mediated haptotactic cell migration within tissue, with particular attention paid to the biological appropriateness of the description of cell-extracellular matrix adhesion. A model is developed that describes the effects of passive and haptotactic migration on the cellular dynamics and growth of pre-necrotic avascular tumours. The model includes a description of the extracellular matrix and its effect on cell migration. Questions are posed as to which cell types act as a source of the extracellular matrix, and the model is used to simulate the possible effects of different matrix sources. Simulations in one-dimensional and spherically symmetric geometry are presented, displaying familiar results such as three-phase tumour growth and tumours comprising a rim of proliferating cells surrounding a non-proliferating region. Novel effects are also described such as cell population splitting and tumour shrinkage due to haptotaxis and appropriate extracellular matrix construction. The avascular tumour model is then extended to describe the internalisation of labelled cells and inert microspheres within multicell tumour spheroids. A novel model of adhesion-receptor mediated haptotactic cell migration is presented and specific applications of the model to tumour invasion processes are discussed. This model includes a more biologically realistic description of cell adhesion than has been considered in previous models of cell population haptotaxis. Through assumptions of fast kinetics, the model is simplified with the identification of relationships between the simplified model and previous models of haptotaxis. Further simpli.cations to the model are made and travelling wave solutions of the original model are then investigated. It is noted that the generic numerical solution routine NAG D03PCF is not always appropriate for the solution of the model, and can produce oscillatory and inaccurate solutions. For this reason, a control volume numerical solver with .ux limiting is developed to provide a better method of solving the cell migration models.
10
Farsad, Nikrooz. "Ultrastructural and Histochemical Characterization of the Zebra Mussel Adhesive Apparatus." Thesis, 2010. http://hdl.handle.net/1807/24271.
Анотація:
Since their accidental introduction into the Great Lakes in mid- to late-1980s, the freshwater zebra mussels, Dreissena polymorpha, have colonized most lakes and waterways across eastern North America. Their rapid spread is partly attributed to their ability to tenaciously attach to hard substrates via an adhesive apparatus called the byssus, resulting in serious environmental and economic impacts. A detailed ultrastructural study of the bysuss revealed a 10 nm adhesive layer at the attachment interface. Distributions of the main adhesive amino acid, 3,4-dihydroxyphenylalanine (DOPA), and its oxidizing (cross-linking) enzyme, catechol oxidase, were determined histochemically. It was found that, upon aging, DOPA levels remained high in the portion of the byssus closest to the interface, consistent with an adhesive role. In contrast, reduced levels of DOPA corresponded well with high levels of catechol oxidase in the load-bearing component of the byssus, presumably forming cross-links and increasing the cohesive strength.
Книги з теми "Adhesive plaque":
1
Silk, Lois Jane. The effects of zinc on the physiology and adhesion of dental plaque bacteria. Manchester: University of Manchester, 1994.
2
Badimon, Lina, and Gemma Vilahur. Atherosclerosis and thrombosis. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0040.
Анотація:
Atherosclerosis is the main underlying cause of heart disease. The continuous exposure to cardiovascular risk factors induces endothelial activation/dysfunction which enhances the permeability of the endothelial layer and the expression of cytokines/chemokines and adhesion molecules. This results in the accumulation of lipids (low-density lipoprotein particles) in the extracellular matrix and the triggering of an inflammatory response. Accumulated low-density lipoprotein particles suffer modifications and become pro-atherogenic, enhancing leucocyte recruitment and further transmigration across the endothelium into the intima. Infiltrated monocytes differentiate into macrophages which acquire a specialized phenotypic polarization (protective or harmful), depending on the stage of the atherosclerosis progression. Once differentiated, macrophages upregulate pattern recognition receptors capable of engulfing modified low-density lipoprotein, leading to foam cell formation. Foam cells release growth factors and cytokines that promote vascular smooth muscle cell migration into the intima, which then internalize low-density lipoprotein via low-density lipoprotein receptor-related protein-1 receptors. As the plaque evolves, the number of vascular smooth muscle cells decline, whereas the presence of fragile/haemorrhagic neovessels increases, promoting plaque destabilization. Disruption of this atherosclerotic lesion exposes thrombogenic surfaces that initiate platelet adhesion, activation, and aggregation, as well as thrombin generation. Both lipid-laden vascular smooth muscle cells and macrophages release the procoagulant tissue factor, contributing to thrombus propagation. Platelets also participate in progenitor cell recruitment and drive the inflammatory response mediating the atherosclerosis progression. Recent data attribute to microparticles a potential modulatory effect in the overall atherothrombotic process. This chapter reviews our current understanding of the pathophysiological mechanisms involved in atherogenesis, highlights platelet contribution to thrombosis and atherosclerosis progression, and provides new insights into how atherothrombosis may be modulated.
3
Badimon, Lina, and Gemma Vilahur. Atherosclerosis and thrombosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0040_update_001.
Анотація:
Atherosclerosis is the main underlying cause of heart disease. The continuous exposure to cardiovascular risk factors induces endothelial activation/dysfunction which enhances the permeability of the endothelial layer and the expression of cytokines/chemokines and adhesion molecules. This results in the accumulation of lipids (low-density lipoprotein particles) in the intimal layer and the triggering of an inflammatory response. Accumulated low-density lipoprotein particles attached to the extracellular matrix suffer modifications and become pro-atherogenic, enhancing leucocyte recruitment and further transmigration across the endothelium into the intima. Infiltrated pro-atherogenic monocytes (mainly Mon2) differentiate into macrophages which acquire a specialized phenotypic polarization (protective/M1 or harmful/M2), depending on the stage of the atherosclerosis progression. Once differentiated, macrophages upregulate pattern recognition receptors capable of engulfing modified low-density lipoprotein, leading to foam cell formation. Foam cells release growth factors and cytokines that promote vascular smooth muscle cell migration into the intima, which then internalize low-density lipoproteins via low-density lipoprotein receptor-related protein-1 receptors becoming foam cells. As the plaque evolves, the number of vascular smooth muscle cells decline, whereas the presence of fragile/haemorrhagic neovessels and calcium deposits increases, promoting plaque destabilization. Disruption of this atherosclerotic lesion exposes thrombogenic surfaces rich in tissue factor that initiate platelet adhesion, activation, and aggregation, as well as thrombin generation. Platelets also participate in leucocyte and progenitor cell recruitment are likely to mediate atherosclerosis progression. Recent data attribute to microparticles a modulatory effect in the overall atherothrombotic process and evidence their potential use as systemic biomarkers of thrombus growth. This chapter reviews our current understanding of the pathophysiological mechanisms involved in atherogenesis, highlights platelet contribution to thrombosis and atherosclerosis progression, and provides new insights into how atherothrombosis may be prevented and modulated.
4
Badimon, Lina, and Gemma Vilahur. Atherosclerosis and thrombosis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0040_update_002.
Анотація:
Atherosclerosis is the main underlying cause of heart disease. The continuous exposure to cardiovascular risk factors induces endothelial activation/dysfunction which enhances the permeability of the endothelial layer and the expression of cytokines/chemokines and adhesion molecules. This results in the accumulation of lipids (low-density lipoprotein particles) in the intimal layer and the triggering of an inflammatory response. Accumulated low-density lipoprotein particles attached to the extracellular matrix suffer modifications and become pro-atherogenic, enhancing leucocyte recruitment and further transmigration across the endothelium into the intima. Infiltrated pro-atherogenic monocytes (mainly Mon2) differentiate into macrophages which acquire a specialized phenotypic polarization (protective/M1 or harmful/M2), depending on the stage of the atherosclerosis progression. Once differentiated, macrophages upregulate pattern recognition receptors capable of engulfing modified low-density lipoprotein, leading to foam cell formation. Foam cells release growth factors and cytokines that promote vascular smooth muscle cell migration into the intima, which then internalize low-density lipoproteins via low-density lipoprotein receptor-related protein-1 receptors becoming foam cells. As the plaque evolves, the number of vascular smooth muscle cells decline, whereas the presence of fragile/haemorrhagic neovessels and calcium deposits increases, promoting plaque destabilization. Disruption of this atherosclerotic lesion exposes thrombogenic surfaces rich in tissue factor that initiate platelet adhesion, activation, and aggregation, as well as thrombin generation. Platelets also participate in leucocyte and progenitor cell recruitment are likely to mediate atherosclerosis progression. Recent data attribute to microparticles a modulatory effect in the overall atherothrombotic process and evidence their potential use as systemic biomarkers of thrombus growth. This chapter reviews our current understanding of the pathophysiological mechanisms involved in atherogenesis, highlights platelet contribution to thrombosis and atherosclerosis progression, and provides new insights into how atherothrombosis may be prevented and modulated.
5
Tumber, Paul Singh, and Philip W. H. Peng. Peripheral Nerve Blocks in Chronic Pain. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0037.
Анотація:
Ultrasound-guided nerve blockade for chronic pain offers advantages over blind landmark-based and fluoroscopic techniques. It allows visualization of soft-tissue structures and spread of the injectate while limiting ionizing radiation exposure. Interventionalists must have both a clear understanding of the anatomy that is being visualized on the ultrasound image and the ability to safely place a needle to the desired target site. Neural blockade of the suprascapular nerve can be useful in the management of chronic shoulder pain such as adhesive capsulitis, frozen shoulder, rotator cuff tear, and glenohumeral arthritis. Intercostal nerve blocks can be helpful for painful conditions that affect the thorax or upper abdomen. The lateral femoral cutaneous nerve local anesthetic block may provide analgesia for procedures involving the region, such as skin harvesting. The pudendal nerve block may be useful for diagnostic or therapeutic purposes in certain cases of chronic pelvic pain involving pudendal neuralgia.
Частини книг з теми "Adhesive plaque":
1
Hwang, Dong Soo, Wei Wei, Nadine R. Rodriguez-Martinez, Eric Danner, and J. Herbert Waite. "A Microcosm of Wet Adhesion: Dissecting Protein Interactions in Mussel Attachment Plaques." In Polymer Adhesion, Friction, and Lubrication, 319–49. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118505175.ch8.
2
Vidali, G., and M. Karimi. "The Interaction of Aromatic Molecules with the Basal Plane of Graphite and Rare Gas Atoms." In Adhesion and Friction, 122–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74987-2_10.
3
Ben-Ze’ev, Avri, José Luis Rodríguez Fernández, Ursula Glück, Daniela Salomon, and Benjamin Geiger. "Changes in Adhesion Plaque Protein Levels Regulate Cell Motility And Tumorigenicity." In Advances in Experimental Medicine and Biology, 147–57. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2578-3_14.
4
Eliseev, Alexander A., Tatiana A. Kalashnikova, Andrey V. Filippov, and Evgeny A. Kolubaev. "Material Transfer by Friction Stir Processing." In Springer Tracts in Mechanical Engineering, 169–88. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-60124-9_8.
Анотація:
AbstractMechanical surface hardening processes have long been of interest to science and technology. Today, surface modification technologies have reached a new level. One of them is friction stir processing that refines the grain structure of the material to a submicrocrystalline state. Previously, the severe plastic deformation occurring during processing was mainly described from the standpoint of temperature and deformation, because the process is primarily thermomechanical. Modeling of friction stir welding and processing predicted well the heat generation in a quasi-liquid medium. However, the friction stir process takes place in the solid phase, and therefore the mass transfer issues remained unresolved. The present work develops the concept of adhesive-cohesive mass transfer during which the rotating tool entrains the material due to adhesion, builds up a transfer layer due to cohesion, and then leaves it behind. Thus, the transfer layer thickness is a clear criterion for the mass transfer effectiveness. Here we investigate the effect of the load on the transfer layer and analyze it from the viewpoint of the friction coefficient and heat generation. It is shown that the transfer layer thickness increases with increasing load, reaches a maximum, and then decreases. In so doing, the average moment on the tool and the temperature constantly grow, while the friction coefficient decreases. This means that the mass transfer cannot be fully described in terms of temperature and strain. The given load dependence of the transfer layer thickness is explained by an increase in the cohesion forces with increasing load, and then by a decrease in cohesion due to material overheating. The maximum transfer layer thickness is equal to the feed to rotation rate ratio and is observed at the axial load that causes a stress close to the yield point of the material. Additional plasticization of the material resulting from the acoustoplastic effect induced by ultrasonic treatment slightly reduces the transfer layer thickness, but has almost no effect on the moment, friction coefficient, and temperature. The surface roughness of the processed material is found to have a similar load dependence.
5
Tomasetti, Eric, Sylvie Derclaye, Mary-Hélène Delvaux, and Paul G. Rouxhet. "Study of Material-Water Interactions Using the Wilhelmy Plate Method." In Advances in Contact Angle, Wettability and Adhesion, 131–53. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118795620.ch8.
6
Ben-Ze’ev, A. "Adhesion Mediated Signaling: The Role of Junctional Plaque Proteins in the Regulation of Tumorigenesis." In Dynamical Networks in Physics and Biology, 41–49. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-662-03524-5_4.
7
Tomczak, Fabio, and Bernard Riedl. "Contact Angle on Two Canadian Woods: Influence of Moisture Content and Plane of Section." In Advances in Contact Angle, Wettability and Adhesion, 297–309. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118795620.ch17.
8
He, F., S. I. Rokhlin, and L. Adler. "Application of SH and Lamb Wave Emat’s for Evaluation of Adhesive Joint in Thin Plate." In Review of Progress in Quantitative Nondestructive Evaluation, 911–18. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0979-6_4.
9
Chen, Donna, and Raafat El-Hacha. "Bond Strength Between Cast-in-Place Ultra-High-Performance- Concrete and Glass Fibre Reinforced Polymer Plates Using Epoxy Bonded Coarse Silica Sand." In Durability of Building and Construction Sealants and Adhesives: 4th Volume, 3–25. 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959: ASTM International, 2012. http://dx.doi.org/10.1520/stp49511t.
10
Chen, Donna, and Raafat El-Hacha. "Bond Strength Between Cast-in-Place Ultra-High-Performance- Concrete and Glass Fibre Reinforced Polymer Plates Using Epoxy Bonded Coarse Silica Sand." In Durability of Building and Construction Sealants and Adhesives: 4th Volume, 3–25. 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959: ASTM International, 2012. http://dx.doi.org/10.1520/stp154520120001.
Тези доповідей конференцій з теми "Adhesive plaque":
1
Wang, Ying, John A. Johnson, Abigail Fulp, Michael A. Sutton, and Susan M. Lessner. "Adhesive Strength of Atherosclerotic Plaques Depends on Collagen Content." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80433.
Анотація:
Atherosclerotic plaque rupture is a major cause of myocardial infarction, coronary thrombosis and stroke. In a previous study, we proposed a new plaque rupture mechanism, plaque separation at the shoulder, and developed a novel quantitative mechanical test to measure the adhesive strength between the atherosclerotic plaque and the underlying vascular wall in mouse models using the local energy release rate, G, as a quantifiable metric for direct comparison of plaque separation strengths (1). We have now investigated structure-function relationships between the local energy release rate and local plaque composition. We hypothesize that adhesive strength varies with plaque composition in mice of different genotypes, and that it correlates with collagen deposition and macrophage content in lesions. Mice which are genetically deficient in matrix metalloproteinase 12 (MMP12), have previously been shown to demonstrate altered lesion composition (2). Therefore, we used apoE knockout (KO) and apoE MMP-12 double knockout (DKO) mice for our experiments and expected to see a difference in local energy release rates between strains.
2
Sancaktar, Erol. "Fatigue Behavior of Adhesive Joints Under Biaxial Loading Conditions." In ASME 1993 Design Technical Conferences. American Society of Mechanical Engineers, 1993. http://dx.doi.org/10.1115/detc1993-0067.
Анотація:
Abstract Fatigue data obtained under biaxial loading conditions for adhesively bonded joints are used to plot S-N type diagrams to assess the effects of biaxiality in loading. Independently Loaded Mixed-Mode Specimens (ILM MS) are used for data collection purposes. These specimens are basically two (steel) beams bonded to be fatigue loaded under cantilever (opening) mode while a simultaneous but physically separate in-plane (static) shear load is also induced with the aid of a small hydraulic piston embedded in the specimen. Application of such static shear loads results in different S-N behavior for the bonded joint. The model adhesives used are Metlbond 1113-2 and Metlbond 1113 solid film thermosetting adhesives similar to those commonly used in aircraft and aerospace industries. The former is an elastomer-modified epoxy adhesive and the latter is identical except that it containes a synthetic earner cloth. Thus, the effects of carrier cloth in adhesive’s S-N behavior is also assessed. Analytically, the classical linear log-log representation of the adhesive S-N data is explored and modifications necessary to reflect the effects of biaxiality in loading and also the presence of a carrier cloth are assessed. The fatigue failure results are also compared with results obtained under monotonic biaxial loading conditions.
3
Hailu, Haftay, and Eyassu Woldesenbet. "Analysis of Adhesion Bond: Rehablitation of Deficient Structures Using Composite Plates." In ASME 2001 Engineering Technology Conference on Energy. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/etce2001-17033.
Анотація:
Abstract The state of considerable number of structurally deficient or functionally obsolete infrastructure in the US, along with the prohibitive cost of replacement has opened a way for the search of innovative methods of rehabilitation. One such method is the use of composite plates adhesively bonded to concrete to prevent the propagation of crack within the concrete structure. Due to their high specific strength and corrosion resistance, composite materials serve better than conventional construction materials. The load transfer and the resulting stress distribution in the composite plate and adhesive layer can be investigated analytically and numerically. In this paper, analytical model is selected and used to analyze and predict the failure conditions of the adhesive. Parametric study is also included to understand the effects of the length and thickness of the adhesion bond, the modulus of the adherents and the adhesive. Finally, a general equation of the adhesion bond strength of the single-lap joint is presented for general shear stress-strain behavior of the adhesive.
4
Tsai, M. Y., C. Y. Huang, C. Y. Chiang, C. Y. Wu, and S. S. Yang. "An Approach to Determining Residual Strains and Moisture Diffusion Coefficients of Cured Adhesives in Electronic Packaging." In ASME 2007 InterPACK Conference collocated with the ASME/JSME 2007 Thermal Engineering Heat Transfer Summer Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/ipack2007-33967.
Анотація:
Polymeric adhesives are popular in the application to electronic or optoelectronic packaging for die attaching, underfilling or interconnection. Their residual strains or stresses (induced by temperature, moisture, and curing shrinkage) and moisture diffusion coefficients have to be determined and cooperated into the package design for better reliability. The purpose of this study is to propose an approach for quantifying adhesive moisture diffusion coefficients and residual strains due to chemical shrinkage, stress relaxation and temperature- and moisture-loading. This approach feature testing fully-cured adhesive/silicon bi-material plates under thermal and moisture loading using Twyman-Green (T/G) interferometry system plus analyses with Timoshenko’s bi-material theory and finite element method (FEM). Three types of adhesives: paste adhesive, film adhesives A and B have been tested for illustrating the approach. The results suggest that the residual strains for the paste adhesive are only induced by CTE mismatch during thermal loading, rather than other factors, after the cured paste adhesive being cooled down to room temperature. On the other hand, the film adhesive A was found to have the additional residual strain caused by chemical shrinkage plus stress relaxation, besides thermal one, is about 2.26×10−3, which accounts for 85% of thermal strains, after the bi-material plate being cooled down to room temperature. Through moisture diffusion test, the average of the coefficients of moisture diffusion and saturated hygro-strains of the film adhesive B under 30°C/85%RH are obtained to be 1.09 × 10−6 mm2/s and 1.51 × 10−3, respectively. From the aforementioned results, it has been demonstrated that this method with a combination of experimental data and analytical tools can be able to determine the residual strains and moisture diffusion coefficients of the cured film or paste adhesives.
5
Turner, Trey N., and Abhimanyu Kumar. "Explosion Response of Cold Bond Corrosion Repairs Applied to Offshore Living Quarters." In ASME 2019 38th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/omae2019-95810.
Анотація:
Abstract Maintaining the integrity of an aging offshore facility often requires the repair of corrosion. With advances in adhesive technology, epoxy adhesives (cold bond repairs) are increasingly being adopted to repair corrosion damage on offshore structures. Structural elements, protection barriers, and occupied buildings, for example a platform living quarters, designated as safety critical often must comply with project or facility performance standards that specify minimum design accidental loading (e.g., from fire, explosions, or impact). In addition to satisfying conventional structural design criteria, a corrosion repaired structure must also perform within acceptable limits when subjected to accidental loads. The present study outlines approaches to assess the performance of cold bond repairs subjected to accidental explosion loads. The living quarters considered in this study featured approximately 50 individual cold bond repairs; each arbitrarily located over the building’s external surfaces. Under accidental blast conditions, failure of a cold bond repair was deemed unacceptable due to the threat of pressure leakage into the building’s interior. As such, the study demanded an analysis capable of considering both the global response of the living quarters as well as the local response of cold bond repairs. There have been several studies conducted by researchers around the globe to evaluate the response characteristics of adhesive bonds. However, these studies are largely focused on experimental, local, and micromechanical analysis of adhesively bonded materials. Numerical analysis of adhesive bonds, for purposes of global structural system response assessments, especially in the case of accidental loading, appear to be nonexistent in available literature. Inspired by this gap, we present a case study involving an assessment of global structural performance of a living quarters building repaired with cold bond adhesives subject to loading due to accidental and rare events. In this study, the local behavior of cold bond adhesives was calibrated using numerical simulations of the ASTM tests specified by the adhesive vendor. The calibrated properties were implemented in finite element analyses used to validate cold bond seal plate repairs at various locations on the living quarters building. The study includes a discussion about the methods and approaches used to model cold bond repairs in a practical and efficient manner. The approach outlined herein provides a useful framework that can be adapted to similar assessments by a practicing engineer responsible for blast analysis of marine structures.
6
Nonaka, Toshihisa, Akira Shimada, Koichi Aoki, and Noboru Asahi. "High thermal conductive adhesive film for Cu and Al plate adhesion in power eectronics package." In 2013 IEEE 63rd Electronic Components and Technology Conference (ECTC). IEEE, 2013. http://dx.doi.org/10.1109/ectc.2013.6575663.
7
Horsmon, Albert W. "Adhesives in Shipbuilding." In SNAME 5th World Maritime Technology Conference. SNAME, 2015. http://dx.doi.org/10.5957/wmtc-2015-278.
Анотація:
Shipbuilding processes usually concentrate on cutting, treating, forming, fitting, welding and painting steel plate for the primary structures of ships. There is no doubt welding is the joining process of choice for primary steel ship structures, but adhesives are gaining ground for non-critical, secondary attachments and temporary attachments used in the shipbuilding process. NSRP Report 0528 investigated the used of adhesives to reduce the number and effects of welded temporary attachments. Since then, advances in adhesive chemical and processing technology opens up many additional applications, so the field warrants a refreshed examination.
8
Pelzmann, Christopher, and Laxman Saggere. "Measurement and Characterization of Stiction Force in Microstructures With Tapered Features." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-48848.
Анотація:
Modeling and measurement of stiction or adhesion due to van der Waals force between microstructures and micro-gripper tools are important for contact-based manipulation and assembly of microstructures. Microfabricated structures commonly feature rough tapered curved surfaces due to undercutting and surface alterations inherent in the microfabrication processes. While several theoretical models exist for calculating adhesive forces between microstructures featuring spherical, cylindrical and flat surfaces, a model for estimating adhesive forces between microstructures featuring tapered curved surfaces is lacking in the literature. This paper presents experimentally measured values of adhesion or pull-off force between a rough tapered curved microstructure from a rough plane surface using a custom micro-cantilever beam as a force sensing mechanism. The paper also introduces an approach to estimate adhesive force between a tapered curved surface and a flat surface by considering the tapered curved surface as a frustum of a cone bound between two cylinders and using the van der Waals force model for cylinders. It is shown that the experimentally measured adhesive force values lie within the upper and lower values of the theoretically estimated van der Waals force values for the two cylinders that define the tapered curved surface geometry.
9
Kamino, Takuya, Takashi Fujimoto, Takashi Yamaguchi, Yasumoto Aoki, Shinsuke Akamatsu, and Hisakazu Horii. "Experimental study on mechanical behavior of combined joint using adhesives and high strength bolts." In IABSE Congress, Christchurch 2021: Resilient technologies for sustainable infrastructure. Zurich, Switzerland: International Association for Bridge and Structural Engineering (IABSE), 2021. http://dx.doi.org/10.2749/christchurch.2021.1017.
Анотація:
<p>As a repair for corrosion damage of a steel bridge, a patch plate-repair using high strength bolts is generally applied. This method requires the surface of the damaged corroded part filled with an epoxy adhesive flat. The load transferring mechanism and slip resistance of such a combined joint with adhesives and high strength frictional bolts aren't clear. Since the shear strength of an adhesive might be increased due to constraint by the bolt axial force, the combined joint's slip resistance would be increased. To clarify the mechanical properties of the combined joint and to propose a new design method for such joints, two experiments have been conducted. The first was a frictional force experiment for adhesive specimens subjected to contact pressure on the surface to evaluate the constraint effect of adhesive on shear strength quantitatively. The last one is a slippage experiment for the combined joints to evaluate its slip coefficient.</p>
10
Amada, S., and T. Hirose. "Application of Plane Fractal Geometry to Adhesion Strength of Thermal Sprayed Coatings." In ITSC 2000, edited by Christopher C. Berndt. ASM International, 2000. http://dx.doi.org/10.31399/asm.cp.itsc2000p1071.
Анотація:
Abstract Adhesion of ceramic coatings considerably depends on the surface characteristics of blasted substrates. The roughened surfaces have two kinds of topographical characteristics, one is of their cross section and the other is of planar. The roughened surfaces is generated by angled grit-blasting process which can be expected to improve the adhesion of ceramic coatings. The topography of the roughened surfaces has fractal characteristics in their cross section and has been more effectively related to the adhesive strength of ceramic coatings than average surface roughness traditionally used. This paper presents that fractal characteristics is evaluated in the planar topography of the blasted surfaces and shows that the planar fractal characteristics is closely related adhesion of ceramic coatings. The planar fractal dimension is evaluated by SIA (Slit Island Analysis) which needs the height data on the roughened surface. Those data are obtained by a laser-microscope in confocal type.
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