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Готові списки джерел за темами / Age-age genetic correlation / Статті в журналах

Щоб переглянути інші типи публікацій з цієї теми, перейдіть за посиланням: Age-age genetic correlation.

Статті в журналах з теми "Age-age genetic correlation"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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1

Mills, Melinda C., and Felix C. Tropf. "Sociology, Genetics, and the Coming of Age of Sociogenomics." Annual Review of Sociology 46, no. 1 (2020): 553–81. http://dx.doi.org/10.1146/annurev-soc-121919-054756.

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Recent years have seen the birth of sociogenomics via the infusion of molecular genetic data. We chronicle the history of genetics, focusing particularly on post-2005 genome-wide association studies, the post-2015 big data era, and the emergence of polygenic scores. We argue that understanding polygenic scores, including their genetic correlations with each other, causation, and underlying biological architecture, is vital. We show how genetics can be introduced to understand a myriad of topics such as fertility, educational attainment, intergenerational social mobility, well-being, addiction,

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2

Tatar, Marc, Daniel E. L. Promislow, Aziz A. Khazaeli, and James W. Curtsinger. "Age-Specific Patterns of Genetic Variance in Drosophila melanogaster. II. Fecundity and Its Genetic Covariance With Age-Specific Mortality." Genetics 143, no. 2 (1996): 849–58. http://dx.doi.org/10.1093/genetics/143.2.849.

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Abstract Under the mutation accumulation model of senescence, it was predicted that the additive genetic variance (VA) for fitness traits will increase with age. We measured age-specific mortality and fecundity from 65,134 Drosophila melanogaster and estimated genetic variance components, based on reciprocal crosses of extracted second chromosome lines. Elsewhere we report the results for mortality. Here, for fecundity, we report a bimodal pattern for VA with peaks at 3 days and at 17–31 days. Under the antagonistic pleiotropy model of senescence, it was predicted that negative correlations wi

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3

Li, Shuai, Ee Ming Wong, JiHoon E. Joo, et al. "Genetic and Environmental Causes of Variation in the Difference Between Biological Age Based on DNA Methylation and Chronological Age for Middle-Aged Women." Twin Research and Human Genetics 18, no. 6 (2015): 720–26. http://dx.doi.org/10.1017/thg.2015.75.

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The disease- and mortality-related difference between biological age based on DNA methylation and chronological age (Δage) has been found to have approximately 40% heritability by assuming that the familial correlation is only explained by additive genetic factors. We calculated two different Δage measures for 132 middle-aged female twin pairs (66 monozygotic and 66 dizygotic twin pairs) and their 215 sisters using DNA methylation data measured by the Infinium HumanMethylation450 BeadChip arrays. For each Δage measure, and their combined measure, we estimated the familial correlation for MZ, D

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4

Kurt, Yusuf. "Age-age correlations and prediction of early selection age for diameter growth in a 35-years old Pinus brutia Ten. Genetic experiment." Forest Systems 30, no. 3 (2021): e010-e010. http://dx.doi.org/10.5424/fs/2021303-17745.

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Aim of study: Forest geneticists developed various methods to predict an early selection age for forest tree species in order to shorten the breeding cycles. This study aims to estimate age-age correlations among diameter growth of trees at different ages and predict early selection age for Pinus brutia Ten. Area of study: P. brutia populations in the study were sampled from the most productive distribution range of the species, which is an important forest tree in the eastern Mediterranean Basin. To understand genetic variation and determine early selection age for the species, a common garde

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5

Nirsatmanto, Arif, Susumu Kurinobu, and Susumu Shiraishi. "EVALUATION FOR THE EFFICIENCY OF EARLY SELECTION IN Acacia mangium SEEDLING SEED ORCHARDS BASED ON AGE TRENDS IN GENETIC PARAMETER." Journal of Forestry Research 9, no. 1 (2012): 16–24. https://doi.org/10.20886/ijfr.2012.9.1.16-24.

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The efficiency of early selection was evaluated based on age trend in genetic parameters using tree height data that was measured periodically repeatedly up to age 3 years of age in four seedling seed orchards <em>of Acacia mangium</em> at South Kalimantan, Indonesia. The four orchards were grouped into two populations based upon their provenances, namely: Papua New Guinea (PNG) and Far North Queensland-Australia (FNQ). A model for time trend of genetic parameters was developed by fitting regression equation to the estimates of variances and correlations using tree height data as an independen

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6

Mullin, T. J., and Y. S. Park. "Genetic parameters and age–age correlations in a clonally replicated test of black spruce after 10 years." Canadian Journal of Forest Research 24, no. 12 (1994): 2330–41. http://dx.doi.org/10.1139/x94-301.

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Height growth at 10 years from striking was assessed for clonally replicated full-sib black spruce (Piceamariana (Mill.) B.S.P) families tested at three locations in central Nova Scotia. Variance components were interpreted according to an additive–dominance–epistasis genetic model and used to derive comparative estimates of gain from various selection and deployment strategies. Field performance at 5 and 10 years was compared with that of the original ortets and families growing in a 25-week greenhouse study, by means of phenotypic and genetic correlation, and rank-change analyses. Between ag

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7

Barbier, Mathieu, Agnès Camuzat, Marion Houot, et al. "Factors influencing the age at onset in familial frontotemporal lobar dementia." Neurology Genetics 3, no. 6 (2017): e203. http://dx.doi.org/10.1212/nxg.0000000000000203.

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Objective:To quantify the effect of genetic factors and generations influencing the age at onset (AAO) in families with frontotemporal lobar dementia (FTD) due to C9ORF72 hexanucleotide repeat expansions and GRN mutations.Methods:We studied 504 affected individuals from 133 families with C9ORF72 repeat expansions and 90 FTD families with mutations in GRN, 2 major genes responsible for FTD and/or amyotrophic lateral sclerosis. Intrafamilial correlations of AAO were analyzed, and variance component methods were used for heritability estimates. Generational effects on hazard rates for AAO were as

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8

Bizelis, J., A. Kominakis, E. Rogdakis, and F. Georgadopoulou. "Genetic parameters of production and reproduetive traits in on a farm tested Danish Large White and Landrace swine in Greece." Archives Animal Breeding 43, no. 3 (2000): 287–98. http://dx.doi.org/10.5194/aab-43-287-2000.

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Abstract. Production and reproduetive traits in Danish Landrace (LD) and Large White (LW) swine were analysed by restricted maximum likelihood methods to obtain heritabilities as well as genetic and phenotypic correlations. Production traits were: age, backfat thickness (BT), muscle depth (MD) and the ratio BT/MD, adjusted to Standard bodyweight of 85 kg. Reproduction traits were: number of pigs born (NB) and number of pigs weaned (NW) per sow and parity. Heritabilities for age, BT, MD and BT/MD were 0.60, 0.44, 0.51 and 0.42 for LD and 0.36, 0.44, 0.37 and 0.45 for LW, respectively. Genetic c

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9

Chekle, Belayneh, Tefera Tadesse, and Zerihun Birhanu. "Chronological Age and Training Age as Determinants of Soccer Specific Speeds." International Journal of Physical Education, Fitness and Sports 8, no. 4 (2019): 108–16. http://dx.doi.org/10.26524/ijpefs19411.

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The main purpose of this study was to unveil how chronological and training age or maturity of soccer players relate or affect linear sprinting speed, repeated sprinting ability (RSA), and change-ofdirection speed (CODS) performance. Competitive soccer players at the Ethiopian national soccer league level participated in the study. A total of 88 volunteered soccer players (age, 22.25±2.27 years old; training age; 9.38±2.78 years) who were free from any kind of injury at the time of data collection completed the study protocol. While age was calculated using a player’s birth certificate, fitnes

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10

Penichet, Eric, Christopher Beam, Kelly Bakulski, et al. "EPIGENETIC AGE ACCELERATION AND IMMUNE CELL COUNT: A TWIN STUDY." Innovation in Aging 7, Supplement_1 (2023): 769. http://dx.doi.org/10.1093/geroni/igad104.2484.

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Abstract Accelerated aging, as measured by epigenetic clocks, is associated with declines in immune system functioning. Investigating the causal basis of this association may provide mechanistic insight into the link between DNA methylation, on which epigenetic clocks are based, and age-related changes in immune cell composition. Using preliminary data from the Louisville Twin Study, this study examined the genetic and environmental sources of covariation between immune cell count (neutrophils, lymphocytes) and GrimAge Acceleration. GrimAge is a composite biomarker derived from 7 DNA methylati

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11

Lu, Pengxin, and Paul Charrette. "Genetic parameter estimates for growth traits of black spruce in northwestern Ontario." Canadian Journal of Forest Research 38, no. 12 (2008): 2994–3001. http://dx.doi.org/10.1139/x08-133.

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Genetic parameters of growth traits were estimated for first-generation selections of black spruce ( Picea mariana (Mill.) BSP) in northwestern Ontario from 720 open-pollinated families and more than 42 000 trees. Unbiased estimates of narrow-sense heritability for tree height growth averaged 0.19, 0.18, and 0.14 at ages 6, 11, and 19 years, respectively, from combined-site analyses compared with 0.25, 0.23, and 0.16 for the same ages from single-site analyses. Heritability estimates for diameter at breast height and stem volume were lower than that of height at age 19, suggesting that tree he

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12

Viken, Richard J., Jaakko Kaprio, and Richard J. Rose. "Personality at Ages 16 and 17 and Drinking Problems at Ages 18 and 25: Genetic Analyses of Data from FinnTwin 16–25." Twin Research and Human Genetics 10, no. 1 (2007): 25–32. http://dx.doi.org/10.1375/twin.10.1.25.

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AbstractWe enrolled more than 3500 same-sex twins from 5 consecutive Finnish birth cohorts into a longitudinal study as each cohort reached age 16. Twins completed the Psychopathic Deviate (Pd) Scale of the Minnesota Multiphasic Personality Inventory at baseline, Sensation Seeking Scale items as each cohort reached age 17, and later, at average ages 18.5 and 25, the Rutgers Alcohol Problem Index (RAPI). Using raw maximum likelihood estimation, we fit a Cholesky model to the 4 variables assessed at 4 ages across the 4 twin types; we estimated genetic and environmental influences on the stabilit

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13

Cheverud, James M., and Larry J. Leamy. "Quantitative genetics and the evolution of ontogeny. III. Ontogenetic changes in correlation structure among live-body traits in randombred mice." Genetical Research 46, no. 3 (1985): 325–35. http://dx.doi.org/10.1017/s0016672300022813.

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SUMMARYOntogenetic series of phenotypic, additive genetic, maternal and environmental correlation matrices are presented and interpreted in the light of recent models for the Ontogenetic origin and variation in correlation between traits. A total of 432 mice from 108 full-sib families raised in a cross-fostering design were used to estimate the various components of phenotypic correlation for five live-body traits at eight ages. The level of genetic and phenotypic correlation decreased with age, while levels of maternal and environmental correlation remained more or less constant. Genetic corr

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14

Portes, Juliana V., Adriana L. Somavilla, André L. Grion, Laila T. Dias, and Rodrigo A. Teixeira. "Short communication: Genetic parameters for post-weaning visual scores and reproductive traits in Suffolk sheep." Spanish Journal of Agricultural Research 16, no. 1 (2018): e04SC01. http://dx.doi.org/10.5424/sjar/2018161-11612.

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The aim of this study was to estimate the coefficients of heritability and genetic correlations among visual scores (conformation, CPW; precocity, PPW; musculature, MPW) and reproductive traits: age at first lambing (AFL) and scrotal circumference (SC) evaluated at 180 days of age in Suffolk lambs. In the statistical model only the additive genetic effect was considered as random effect. The heritability estimates by univariate analyses for CPW, PPW, MPW, AFL and SC were 0.08, 0.12, 0.09, 0.20 and 0.22, respectively. The genetic correlations among AFL and CPW, PPW, MPW were -0.26, 0.19, and 0.

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15

Finkel, Deborah, and Matt McGue. "Age Differences in the Nature and Origin of Individual Differences in Memory: A Behavior Genetic Analysis." International Journal of Aging and Human Development 47, no. 3 (1998): 217–39. http://dx.doi.org/10.2190/jepx-g60a-6qk3-9dr3.

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Measures of memory performance and cognitive and lifestyle variables were obtained from 147 younger twin pairs (27 to 60 years) and 194 older twin pairs (60 to 94 years) as part of the Minnesota Twin Study of Adult Development and Aging. Correlational and behavior genetic analyses were combined to investigate age differences in 1) the relationship between memory performance and cognitive and lifestyle variables, 2) genetic and environmental influences on memory performance, and 3) genetic and environmental mediation of the relationship between memory and predictor variables. No age differences

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16

Apiolaza, Luis A., Arthur R. Gilmour, and Dorian J. Garrick. "Variance modelling of longitudinal height data from a Pinus radiata progeny test." Canadian Journal of Forest Research 30, no. 4 (2000): 645–54. http://dx.doi.org/10.1139/x99-246.

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Variance components were estimated using alternative structures for the additive genetic covariance matrix (G0), for height (m) of trees measured at 10 unequally spaced ages in an open-pollinated progeny test. These structures reflected unstructured, autoregressive, banded correlation and random regressions models. The residual matrix (R0) was unstructured, and the block and plot strata matrices were autoregressive. The best model for G0 considering the likelihood value and number of parameters was the autoregressive correlation form with age-specific variances and time on a natural logarithm

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17

Rudiné Mezei, Anita, János Posta, and Sándor Mihók. "Random regression models for genetic evaluation of performance of the Hungarian show-jumping horse population." Acta Agraria Debreceniensis, no. 59 (April 23, 2014): 87–91. http://dx.doi.org/10.34101/actaagrar/59/2010.

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The aim of the study was to estimate genetic parameters for show-jumping competition performance using random regression model. Show-jumping competition results collected between 1996 and 2009 were analyzed. The database contained 272 951 starts of 8020 horses. Identity number and gender of the horse, rider, competition date, the level of the competition and placing were recorded in the database. Competition levels were categorized into five groups. Weighted – competition level used – square root transformed placing was used to measure performance of horses. The random regression model include

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18

Crews Jr., D. H., and D. J. Porteous. "Age of dam and age at measurement adjustments and genetic parameters for scrotal circumference of Canadian Hereford bulls." Canadian Journal of Animal Science 83, no. 2 (2003): 183–88. http://dx.doi.org/10.4141/a02-080.

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The objective of the study was to estimate age of dam and age at measurement as adjustment factors for scrotal circumference in Canadian Hereford bulls (n = 9029) and to estimate genetic parameters for scrotal circumference, and birth and yearling weights. Quadratic effects of age at measurement and the interaction of age of dam with age at measurement were not important. Adjustment factors recommended for yearling bulls were 1.02, 0.33, 0.10, and 0.16 cm to adjust scrotal circumference of sons of 2-, 3-, 4-, and ≥ 10-yr-old cows to a mature dam (5 to 9 yr of age) equivalent. The linear partia

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19

Atramentova, L. A., and O. P. Barbul. "AGE OF DIABETES MELLITUS MANIFESTATION. REGRESSION ANALYSIS." Problems of Endocrine Pathology 31, no. 1 (2010): 35–40. http://dx.doi.org/10.21856/j-pep.2010.1.05.

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First-degree relatives of a diabetic patient run a high risk of being afflicted with diabetes mellitus. For genetic estimation and evaluation of a possible age of diabetes mellitus manifestation in a patient’s relatives it is worthwhile using a correlation coefficient and a regression equation, which were worked out in the present study.

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20

NIKITIN, A. G., and R. J. SHMOOKLER REIS. "Role of transposable elements in age-related genomic instability." Genetical Research 69, no. 3 (1997): 183–95. http://dx.doi.org/10.1017/s0016672397002772.

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Genetic instability is associated with aging in many species. One of the initiating factors for genetic instability is the movement of transposable elements (TEs), which occur in all prokaryotic and eukaryotic organisms. The hypothesis that TEs could be involved in the aging process is discussed and the correlation between aging and activity of TEs is analysed in a variety of biological systems.

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21

Ivkovich, Milosh, Gene Namkoong, and Mathew Koshy. "Genetic variation in wood properties of interior spruce. I. Growth, latewood percentage, and wood density." Canadian Journal of Forest Research 32, no. 12 (2002): 2116–27. http://dx.doi.org/10.1139/x02-138.

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Quantitative genetic variation in growth, latewood percentage, and wood density was investigated for British Columbia's interior spruce (the common name for white spruce, Picea glauca (Moench) Voss; Engelmann spruce, Picea engelmanni Parry ex Engelm.; and their hybrids). The study included 160 half-sib families from the East Kootenay and Prince George regions. At the time of sampling, progeny tests for those two regions were 20 and 22 years old, respectively. Univariate and multivariate restricted maximum likelihood (REML) estimates of genetic parameters were obtained. Estimates of genetic var

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22

Sarma, Olympica, R. S. Barwal, Mubashir Ali Rather, C. B. Singh, and Shiwanshu Tiwari. "Genetic and Phenotypic Correlations between Production and Reproduction Traits in Frieswal Cattle under Field Progeny Testing Programme." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 21 (2024): 42–52. http://dx.doi.org/10.56557/upjoz/2024/v45i214615.

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Aim: To estimate the genetic and phenotypic correlations in production and reproduction traits in Frieswal Cattle under FPT. Place and Duration of Study: G B Pant University of Agricultural and Technology, Pantnagar, Uttarakhand, India, Between March, 2023 to March, 2024. Methodology: The present study was conducted on Frieswal cattle, a synthetic breed, using data from 1163 first lactation records, progenies of 67 sires, spread over period of nine years (2013-2021) as part of an ongoing field progeny testing programme at GBPUA&T, Pantnagar, Uttarakhand. The study aimed to estimate genetic

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23

Brzáková, Michaela, Ludmila Zavadilová, Josef Přibyl, Petr Pešek, Eva Kašná, and Anita Kranjčevičová. "Estimation of genetic parameters for female fertility traits in the Czech Holstein population." Czech Journal of Animal Science 64, No. 5 (2019): 199–206. http://dx.doi.org/10.17221/51/2018-cjas.

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Genetic parameters for fertility traits in Czech Holstein population were estimated. The database obtained from the Czech-Moravian Breeders Corporation with 6 414 486 insemination records between years 2005–2015 was used. Date of calving of the selected animals was taken from the database of milk records from 2005–2015. Fertility traits were age at first service (AFS), age at first calving (AFC), days open (DO), calving interval (CI) and first service to conception interval in cows (FSC-C) and heifers (FSC-H). The heritability of each trait was estimated using single-trait animal models. The m

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24

Rojas de Oliveira, Hinayah, Henrique Torres Ventura, Edson Vinícius Costa, et al. "Meta-analysis of genetic-parameter estimates for reproduction, growth and carcass traits in Nellore cattle by using a random-effects model." Animal Production Science 58, no. 9 (2018): 1575. http://dx.doi.org/10.1071/an16712.

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Meta-analysis based on a random-effects model is used to summarise and overcome the variability between divergent parameter estimates. We proposed a meta-analysis of published heritability and genetic-correlation estimates for reproduction, growth and carcass traits in purebred Nellore cattle. In total, 197 heritability and 107 genetic-correlation estimates from 62 scientific publications were used here. Most of traits (gestation length; weights at birth, 120, 210, 365 and 550 days of age; mature weight and all carcass traits) presented direct heritability estimates ranging from 0.20 to 0.40.

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25

Blada, I., and F. Popescu. "Diallel Crossing in Pinus cembra: V. Age Trends in Genetic Parameters and Genetic Gain for Height." Silvae Genetica 61, no. 1-6 (2012): 66–79. http://dx.doi.org/10.1515/sg-2012-0009.

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AbstractA full diallel mating design (10 parents) was carried out in a Swiss stone pine panmictic population from the Carpathian Mountains. At age six, after nursery testing, the progenies were field planted to one site, using a completely randomized block design with 100 families, four replicates and a 15 tree row-plot per replication, spaced 2.5 × 2.5 m. Total and annual height of all individuals of this test was assessed at successive ages, between ages eight and 16. In addition, weight of 100 seeds and cotyledon number were considered in correlation analyses. Significant differences occurr

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26

Lopez, Bryan Irvine, Kier Gumangan Santiago, Kangseok Seo, et al. "Genetic Parameters of Birth Weight and Weaning Weight and Their Relationship with Gestation Length and Age at First Calving in Hanwoo (Bos taurus coreanae)." Animals 10, no. 6 (2020): 1083. http://dx.doi.org/10.3390/ani10061083.

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Hanwoo is one of the most economically important animal species in Korea due to its significant contribution to nutrition. However, the current selection index only focuses to improve carcass traits of Hanwoo. Thus, this study aimed to estimate the genetic parameters of birth weight (BW) and weaning weight (WW) and their genetic and phenotypic relationship to the age at first calving (AFC) and gestation length (GL) of Hanwoo. The genetic parameters for birth weight (BW) and weaning weight (WW) were estimated using the data obtained from 52,173 and 35,800 Hanwoo calves born from February 1998 t

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27

Montaldo, Hugo H., Alejandra Pelcastre-Cruz, Héctor Castillo-Juárez, Felipe J. Ruiz-López, and Filippo Miglior. "Genotype × environment interaction for fertility and milk yield traits in Canadian, Mexican and US Holstein cattle." Spanish Journal of Agricultural Research 15, no. 2 (2017): e0402. http://dx.doi.org/10.5424/sjar/2017152-10317.

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The objective of this study was to evaluate genotype × environment interaction (G×E) between Canada, the United States and Mexico for fertility and milk yield traits using genetic correlations between countries estimated from genetic evaluations of sires. Genetic correlation between Mexican and Canadian Holsteins for age at first calving was ≤ 0.48 and lower than the simulated value obtained accounting for data structure and selection effects. For calving interval, genetic correlation between Mexico and Canada ranged from 0.48 to 0.69. Genetic correlation between calving interval in Mexico (mu

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28

Foster, G. Sam. "Trends in Genetic Parameters with Stand Development and Their Influence on Early Selection for Volume Growth in Loblolly Pine." Forest Science 32, no. 4 (1986): 944–59. http://dx.doi.org/10.1093/forestscience/32.4.944.

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Abstract Analysis was conducted on data from a 15-year-old progeny test of 11 open-pollinated families of loblolly pine. Plots consisted of 49-tree blocks of single families, and measurements were taken annually for the first 8 years and at 10 and 15 years. Three types of analysis were used to explore early selection for a more mature trait. These analyses included: age-related trends in genetic and environmental variances, juvenile-mature genetic correlations, and indirect selection. The age-related trends varied by trait. The trends for additive genetic variance ranged from flat (survival) t

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29

Zeng, L. H., Q. Zhang, B. X. He, et al. "Age Trends in Genetic Parameters for Growth and Resin-Yielding Capacity in Masson Pine." Silvae Genetica 62, no. 1-6 (2013): 7–17. http://dx.doi.org/10.1515/sg-2013-0002.

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AbstractMasson pine (Pinus massoniana Lamb) has long been employed as a main source of pine resin in China. To get a better understanding of genetic regulation of resinyielding capacity (RYC), a total of 50 open-pollinated families of masson pine were planted at three testing sites for progeny testing. Investigation was conducted at ages 7, 9, 11, 13, 15, 20, 24 and 26 years to study inheritance, age-age genetic correlation, and early selection efficiency for RYC, height (HT), diameter at breast height (DBH) and volume of individual tree (VOL). Growth characteristics increased gradually with a

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30

Flôres Júnior, Paulo César, Vanessa Ishibashi, Jorge Luis Monteiro de Matos, Diego Tyszka Martinez, and Antonio Rioyei Higa. "FEASIBILITY OF EARLY Pinus taeda L. SELECTION TO ASSESS GROWTH VARIABLES IN PROGENY TEST." FLORESTA 51, no. 4 (2021): 937. http://dx.doi.org/10.5380/rf.v51i4.74441.

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Forest species breeding programs require a long period-of-time for plants to reach the proper age to enable selecting superior genotypes, which is a critical factor in selection processes. Thus, the aims of the current study are to estimate genetic parameters in juvenile and adult plants (6, 10 and 20 years) in order to investigate genetic correlations between variables at different ages and at certain ages; as well as to determine whether it is possible performing efficient early selection in juvenile plants. The test was implemented in 1997; it comprised 120 progenies and followed a randomiz

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Cheng, Yuan-Fang, Cheng-Yi Yang, and Meng-Che Tsai. "Shared Genetics between Age at Menarche and Type 2 Diabetes Mellitus: Genome-Wide Genetic Correlation Study." Biomedicines 12, no. 1 (2024): 157. http://dx.doi.org/10.3390/biomedicines12010157.

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Background: Age at menarche (AAM) has been associated with type 2 diabetes mellitus (T2DM). However, little is known about their shared heritability. Methods: Our data comes from the Taiwan Biobank. Genome-wide association studies (GWASs) were conducted to identify single-nucleotide polymorphisms (SNPs) related to AAM-, T2DM-, and T2DM-related phenotypes, such as body fat percentage (BFP), fasting blood glucose (FBG), and hemoglobin A1C (HbA1C). Further, the conditional false discovery rate (cFDR) method was applied to examine the shared genetic signals. Results: Conditioning on AAM, Quantile-

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Blomquist, Gregory E. "Trade-off between age of first reproduction and survival in a female primate." Biology Letters 5, no. 3 (2009): 339–42. http://dx.doi.org/10.1098/rsbl.2009.0009.

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Trade-offs are central to life-history theory but difficult to document. Patterns of phenotypic and genetic correlations in rhesus macaques, Macaca mulatta —a long-lived, slow-reproducing primate—are used to test for a trade-off between female age of first reproduction and adult survival. A strong positive genetic correlation indicates that female macaques suffer reduced adult survival when they mature relatively early and implies primate senescence can be explained, in part, by antagonistic pleiotropy. Contrasts with a similar human study implicate the extension of parental effects to later a

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Atwood, Ryan A., Timothy L. White, and Dudley A. Huber. "Genetic parameters and gains for growth and wood properties in Florida source loblolly pine in the southeastern United States." Canadian Journal of Forest Research 32, no. 6 (2002): 1025–38. http://dx.doi.org/10.1139/x02-025.

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One hundred and thirteen open-pollinated families from Florida source loblolly pine (Pinus taeda L.) were tested in four states in the southeastern United States. Heritabilities and genetic correlations were estimated for volume, specific gravity, and latewood percentage at three different growth stages: juvenile (ages 010 years), mature (1117 years), and total (017 years). Heritabilities of growth traits (0.090.11) were consistently lower than for wood property traits (0.160.33). Growth traits for Florida loblolly exhibited high genotype × environment interaction (rB = 0.44), whereas woo

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Harroud, Adil, John A. Morris, Vincenzo Forgetta, et al. "Effect of age at puberty on risk of multiple sclerosis." Neurology 92, no. 16 (2019): e1803-e1810. http://dx.doi.org/10.1212/wnl.0000000000007325.

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ObjectiveTo investigate the potential for a causal effect of age at puberty on multiple sclerosis (MS) susceptibility using a mendelian randomization (MR) approach.MethodsWe used 372 genetic variants strongly associated with age at menarche in a genome-wide association study (GWAS) involving 329,245 women. The genetic architecture of pubertal timing across both sexes is highly correlated (genetic correlation [rg] = 0.75, p = 1.2 × 10−79), allowing these variants to provide reliable insight into pubertal timing in males as well. The effect of pubertal timing on risk of MS was measured with summ

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Lee, Anthony J., Dorian G. Mitchem, Margaret J. Wright, Nicholas G. Martin, Matthew C. Keller, and Brendan P. Zietsch. "Facial averageness and genetic quality: testing heritability, genetic correlation with attractiveness, and the paternal age effect." Evolution and Human Behavior 37, no. 1 (2016): 61–66. http://dx.doi.org/10.1016/j.evolhumbehav.2015.08.003.

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Wilkinson, Paul O., Maciej Trzaskowski, Claire M. A. Haworth, and Thalia C. Eley. "The role of gene–environment correlations and interactions in middle childhood depressive symptoms." Development and Psychopathology 25, no. 1 (2013): 93–104. http://dx.doi.org/10.1017/s0954579412000922.

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AbstractDepression is known to be associated with a wide array of environmental factors. Such associations are due at least in part to genetic influences on both. This issue has been little explored with preadolescent children. Measures of family chaos and parenting style at age 9 and child depressive symptoms at age 12 were completed by 3,258 twin pairs from the Twins Early Development Study and their parents. Quantitative genetic modeling was used to explore common and unique genetic and environmental influences on both family environment and later depressive symptoms. Depressive symptoms at

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HASSAN, W. A., N. I. DIM, O. A. OSINOWO, and B. Y. ABUBAKAR. "GENETIC AND PHENOTYPIC CORRELATIONS FOR BODY WEIGHTS IN YANKASA SHEEP." Nigerian Journal of Animal Production 18 (January 12, 2021): 12–18. http://dx.doi.org/10.51791/njap.v18i.1931.

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Using paternal half-sib (PHS) analysis, coefficients of genetic and phenotypic correlations be- tween body weights of Yankasa lambs at birth, weaning (three months), six months, nine months and one year of age were estimate. The highest genetic correlation coefficient of 0.33 was obtained between birth and yearling weight. Six- month weight had very low and negative genetic correlation with yearling weight (-0.04). Phenotypic correlation coefficients for the various body weights pairs were positive and mostly of medium magnitude (0.12 -0.47).

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Hess, Andrew, Tom W. Murphy, Jim E. Miller, and Joan M. Burke. "378 Genetic Parameter Estimates of Post-Weaning Growth and Gastrointestinal Nematode Infection Traits of Katahdin Lambs." Journal of Animal Science 101, Supplement_3 (2023): 303. http://dx.doi.org/10.1093/jas/skad281.362.

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Abstract The objective of this study was to estimate heritability of, and genetic correlations between lamb growth and gastrointestinal nematode (GIN) infection. Lambs were weighed and weaned at ~60 days of age and body weight (BW), fecal egg count (FEC), FAMACHA score (FAM) and packed cell volume (PCV) were recorded at ~90, 120, and 150 d of age. Lambs were not dewormed and FEC was transformed as: LFEC = log10(FEC+25). Average daily gain (ADG) was calculated from weaning to 90 days of age (ADG90) as well as 90 to 120 (ADG120) and 120 to 150 days (ADG150). Each trait (ADG, LFEC, PCV and FAM) w

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Bhave, K. G., K. Thilak Pon Jawahar, P. Kumarasamy, et al. "Genetic and non-genetic factors affecting semen production and quality characteristics of Gir cattle breed under semi-arid climate." August-2020 13, no. 8 (2020): 1714–18. http://dx.doi.org/10.14202/vetworld.2020.1714-1718.

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Aim: This study aims to evaluate genetic and non-genetic factors influencing semen production potential of Gir bulls. Materials and Methods: Data on semen quantity (n=6911) and quality (n=466) available from January 2011 to December 2018 at BAIF's frozen semen station, Jind, Haryana, India, were utilized for the study. Factors, namely, season of collection, age at collection, and bull (random effect) were studied for their effect on quantitative and qualitative semen traits. Least square means for the traits were obtained using a general linear model. The effect of age within bull for repeatab

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Oliveira, M. R., D. M. Azevêdo, C. Malhado, L. Pires, R. Martins Filho, and S. Sousa Júnior. "Weight evaluation of Tabapuã cattle raised in northeastern Brazil using random-regression models." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 69, no. 2 (2017): 457–64. http://dx.doi.org/10.1590/1678-4162-9070.

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ABSTRACT The objective of this study is to compare random-regression models used to describe changes in evaluation parameters for growth in Tabapuã bovine raised in the Northeast of Brazilian. The M4532-5 random-regression model was found to be best for estimating the variation and heritability of growth characteristics in the animals evaluated. Estimates of direct additive genetic variance increased with age, while the maternal additive genetic variance demonstrated growth from birth to up to nearly 420 days of age. The genetic correlations between the first four characteristics were positive

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Li, Li, and Harry X. Wu. "Efficiency of early selection for rotation-aged growth and wood density traits in Pinus radiata." Canadian Journal of Forest Research 35, no. 8 (2005): 2019–29. http://dx.doi.org/10.1139/x05-134.

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A total of 1097 cross-sectional wood disks from breast height were sampled from two rotation-aged (27 and 31 years from planting) genetic trials of radiata pine (Pinus radiata D. Don) in Australia to estimate the genetic correlation between early and rotation-aged growth and wood quality traits and the efficiency of early selection. Annual growth-ring width and density, diameter at breast height (DBH), and area-weighted density (AD) from 30 open-pollinated families were measured using X-ray densitometry. Genotype × site interactions were not significant for density and growth traits. Ring dens

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Sung, Joohon, Kayoung Lee, Yun-Mi Song, and Ji-Hae Kim. "Relationships Between State and Trait Anxiety Inventory and Alcohol Use Disorder Identification Test Scores Among Korean Twins and Families: The Healthy Twin Study." Twin Research and Human Genetics 14, no. 1 (2011): 73–78. http://dx.doi.org/10.1375/twin.14.1.73.

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We explored heritabilities of the State and Trait Anxiety Inventory (STAI) and the Alcohol Use Disorders Identification Test (AUDIT), and associations including genetic and environmental correlations between the phenotypes among Korean twins and their families. We analyzed the data of 1,748 participants (835 men, 913 women, 656 individuals of monozygotic twins, 173 individuals of same-sexed dizygotic twins, 919 non-twin family members, age 30–79 years) from the Healthy Twin study. Heritabilities and bivariate analyses were assessed using the SOLAR package software. In the methods of generalize

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Gustavson, Daniel E., Carol E. Franz, Matthew S. Panizzon, et al. "Genetic and Environmental Associations Among Executive Functions, Trait Anxiety, and Depression Symptoms in Middle Age." Clinical Psychological Science 7, no. 1 (2018): 127–42. http://dx.doi.org/10.1177/2167702618805075.

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Multiple executive functions (EFs) are associated with trait anxiety and depression symptoms, but it is unclear how genetic and/or environmental factors account for these associations and whether they are explained by general variance underlying multiple EFs (i.e., common EF). In this study, 1,207 male twins completed seven EF tasks and measures of trait anxiety and depression symptoms at an average age of 62 years. The common EF factor was associated with both anxiety ( r = −.24) and depression ( r = −.32) symptoms. Anxiety and depression had a near-complete genetic overlap ( rg = .96). Genet

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Weller, Joel Ira, Moran Gershoni, and Ephraim Ezra. "Breeding Dairy Cattle for Female Fertility and Production in the Age of Genomics." Veterinary Sciences 9, no. 8 (2022): 434. http://dx.doi.org/10.3390/vetsci9080434.

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Phenotypic and genetic changes for female fertility and production traits in the Israeli Holstein population over the last three decades were studied in order to determine if long term selection has resulted in reduced heritability and negative genetic correlations. Annual means for conception status, defined as the inverse of the number of inseminations to conception in percent, decreased from 55.6 for cows born in 1983 to 46.5 for cows born in 2018. Mean estimated breeding values increased by 1.8% for cow born in 1981 to cows born in 2018. Phenotypic records from 1988 to 2016 for the nine Is

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Pantelic, Vlada, M. M. Petrovic, S. Aleksic, Ljiljana Sretenovic, D. Ostojic-Andric, and Z. Novakovic. "Investigation of the genetic correlation between milk and fertility traits of first calving cows of Simmental breed." Biotehnologija u stocarstvu 24, no. 5-6 (2008): 1–8. http://dx.doi.org/10.2298/bah0806001p.

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Investigation of the production capacity of cattle for the purpose of increase of milk and milk fat production, as well as number of calves, greatly depends on phenotypic and genetic variability, heritability and correlation between desired traits, and on production level in the population. This research included 3.461 first calving cows of Simmental breed under control and reared on farms of individual agricultural producers on the territory of Republic of Serbia. Genetic correlations were calculated using equation of mixed model which included the effect of bull-sire, breeding region, year a

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Peter, Inga, Michael Vainder, and Gregory Livshits. "Genetic analysis of motor milestones attainment in early childhood." Twin Research 2, no. 1 (1999): 1–9. http://dx.doi.org/10.1375/twin.2.1.1.

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AbstractThe age of attainment for four motor developmental traits, such as turning over, sitting up without support, pulling up to a standing position and walking without support, was examined in 822 children, including 626 siblings from families with 2 to 6 children, 68 pairs of dizygotic twins and 30 pairs of monozygotic twins. Correlation analysis, carried out separately for each type of sibship, showed the highest pairwise correlations in monozygotic twins and the lowest correlation in non-twin siblings for all motor milestones. Variance component analysis was used to decompose the differe

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Hegde, Maheshwar, P. Ramteke, and K. Subramanian. "Genetic variation and interse genetic correlation of seedling characteristics in Teak (Tectona grandis L.)." Indian Journal of Forestry 27, no. 1 (2004): 19–24. http://dx.doi.org/10.54207/bsmps1000-2004-ylrin0.

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Genetic variation in seedling characteristics was studied in 15 seedlots collected from selected trees representing different regions of Peninsular India and selected clones planted in CSO at Walayar (Kerala). Significant variations were obtained in a nested ANOVA in all the six characteristics, viz., seedling height, collar diameter, number of nodes, leaf length, leaf breadth and leaf length/breadth ratio measured at 3 months and 6 months of age in nursery. Genetic correlation among characters changed as the age advanced. Narrowsense heritability was higher for seedling height, collar diamete

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Franz, Carol E., Michael D. Grant, Kristen C. Jacobson, et al. "Genetics of Body Mass Stability and Risk for Chronic Disease: A 28-Year Longitudinal Study." Twin Research and Human Genetics 10, no. 4 (2007): 537–45. http://dx.doi.org/10.1375/twin.10.4.537.

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AbstractWe examined the contributions of genetic and environmental factors to body mass index (BMI) over approximately 28 years. Participants were 693 male, predominantly middle-class, twins (355 monozygotic, 338 dizygotic) from the Vietnam Era Twin Registry. The phenotypic correlation between age 20 and age 48 BMI was 0.52; the genetic correlation was 0.60. Most of the remaining variance at both times was accounted for by nonshared environmental factors. Since genetic factors are not perfectly correlated, this indicates that other genes affect BMI at one or both time points, leaving room for

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Giess, Lane K., Scott E. Speidel, Ryan J. Boldt, Wade R. Shafer, Milton G. Thomas, and R. Mark Enns. "118 Variance Components for Age at First Calving and Yearling Weight When Accounting for Age Differences at Fixed Breeding Dates in a Contemporary Group." Journal of Animal Science 101, Supplement_3 (2023): 11–12. http://dx.doi.org/10.1093/jas/skad281.015.

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Abstract The ability of a heifer to calve earlier in a breeding season has implications on the economic success of heifers in a production system. Heifers that calve earlier in a calving season have increased calf performance, improved subsequent fertility, and a longer productive life in the herd. Production systems typically breed heifers during fixed breeding dates, with heifers of variable ages in the same contemporary group. The objective of this study was to determine if heifer yearling weight (YW) or age differences going into a fixed breeding period influenced the additive genetic vari

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Tabor, Elżbieta, Małgorzata Bach, Aleksandra Werner, Bogna Drozdzowska, and Wojciech Pluskiewicz. "The Impact of Environmental and Genetic Factors on Bone Quality in Monozygotic and Dizygotic Twins." Biomedicines 10, no. 10 (2022): 2360. http://dx.doi.org/10.3390/biomedicines10102360.

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The purpose of the research was to assess the genetic and environmental influences on bone properties. One hundred thirty-two pairs of twins (99/33 monozygotic/dizygotic) underwent anthropometric measurements and phalangeal quantitative ultrasound (DBM Sonic 1200, Igea, Italy) measuring the amplitude speed of sound (AD-SoS, m/s). The mean age was 16.78 ± 12.35 years for monozygotic twins and 14.30 ± 8 years for dizygotic. Interpair and intrapair correlations between twins were calculated. In the groups of monozygotic and dizygotic twins, Ad-SoS correlated significantly with age (r = 0.56–0.73,

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