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BAPTISTA, Susana Simões Sales Gonçalves. "Lyme borreliosis in Portugal: study on vector(s), agent(s) and risk factor(s)." Doctoral thesis, Instituto de Higiene e Medicina Tropical, 2006. http://hdl.handle.net/10362/56912.
Анотація:
A situação da Borreliose de Lyme (BL) em Portugal foi avaliada com base na identificação dos
principais vectores (carraças) e sua distribuição, taxas de infecção com os agentes do complexo
Borrelia burgdorferi sensu lato (s.l.) e os casos humanos com confirmação laboratorial.
Ixodes ricinus, o principal vector desta doença, foi estudado durante um período de 5 anos na
Tapada Nacional de Mafra (área protegida), durante o qual foi observado um ciclo unimodal para
todos os estados de desenvolvimento, por um período de 1 a 1,5 anos. Confirmou-se uma
correlação significativa entre a variação sazonal da abundância de carraças e algumas variáveis
climáticas, nomeadamente, a temperatura, humidade e precipitação. Além de I. ricinus, foram
colhidas outras espécies de carraças tais como Dermacentor marginatus, Haemaphysalis
punctata, Rhipicephalus sanguineus e Ixodes hexagonus. As taxas de infecção atingiram valores
globais de 11,8% para I. ricinus e de 5,2% para as restantes espécies, com identificação de vários
agentes do complexo B. burgdorferi s.l., provavelmente relacionada com a acentuada diversidade
de hospedeiros presentes na área investigada.
Num estudo a nível nacional, durante 4 anos, foram amostrados 55 pontos para colheita de
vectores, tendo-se obtido um total de 2801 carraças distribuídas pelos seguintes géneros/espécies
Rhipicephalus spp, D. marginatus, I. ricinus, Hy. marginatum, H. punctata e Ixodes spp, com
diferentes taxas de colheita. Todos estes ixodídeos foram encontrados infectados por B.
lusitaniae, a principal espécie genómica detectada no vector (até ao momento). Em Portugal, para
além da Tapada Nacional de Mafra, foram apenas identificadas estirpes patogénicas de B. garinii,
num local perto de Coimbra (Soure).
A confirmação laboratorial de casos humanos foi obtida com base no diagnóstico de rotina desta
doença, realizado no Instituto de Higiene e Medicina Tropical, quer ao nível serológico por
Western-Blot (15.5%), quer por amplificação do espaço intergénico de rRNA 5S-23S (rrf-rrl) de B.
burgdorferi s.l. (28%). Neste último caso, foram identificadas duas espécies genómicas
patogénicas (B. garinii e B. afzelii), além de B. lusitaniae. A principal proveniência dos doentes
com Borreliose de Lyme foi Lisboa, Coimbra, Tomar, Viseu e Almada.Os principais factores envolvidos na distribuição das carraças e consequentemente no ciclo
epidemiológico da Borreliose de Lyme em Portugal encontram-se associados com o clima
(temperatura, humidade e precpitação) e composição do habitat (áreas expostas, florestas mistas
e de caducas). A estrutura da paisagem (ex. fragmentação) foi igualmente considerada como um
factor essencial para a presença de carraças numa determinada área. Com base nestas variáveis,
mapas de risco foram criados para os três ixodídeos (I. ricinus, D. marginatus, Rhipicephalus spp)
potencialmente mais implicados na transmissão dos agentes de BL em Portugal
Em conclusão, a Borreliose de Lyme existe em Portugal e apresenta uma epidemiologia
complexa, como a seguir se demonstra: i) além do vector Europeu, registaram-se outros
potenciais vectores, susceptíveis de estarem associados a uma maior diversidade de hospedeiros
reservatórios (ainda por investigar) e biótopos específicos, ii) uma elevada diversidade de
espécies genómicas do complexo B. burgdorferi sensu lato, decorrente deste espectro alargado
de vectores-reservatórios, iii) e uma distribuição generalizada de doentes de BL, com importantes
taxas de infecção, resultante da referida diversidade de agentes patogénicos, não só das duas
espécies genómicas mais reconhecidas na Europa (B. garinii e B. afzelii), como da recentemente
isolada B. lusitaniae, indutora de um quadro clínico aparentemente diferente e restricto à zona do
Mediterrâneo.The status of Lyme Borreliosis (LB) in Portugal was evaluated through identification of the main vectors (ticks), their distribution, infection rates with Borrelia burgdorferi sensu lato species and human disease cases. Ixodes ricinus, the main vector of this disease, was studied extensively in a 5-year focal study in Tapada Nacional de Mafra, a protected area. An unimodal dynamic cycle was found for all developmental stages and a 1-1.5 year developmental cycle was observed. Climatic variables, including temperature, humidity and precipitation were significantly correlated with seasonal variation in I. ricinus abundance. Other tick species, namely Dermacentor marginatus, Haemaphysalis punctata, Rhipicephalus sanguineus and Ixodes hexagonus, were also collected. An overall infection rate of 11.8% for I. ricinus and 5.2% for the other tick species were detected. Several Borrelia species were identified in these ticks, probably due to the great variety of hosts present in this area. In a nationwide study during a 4-years period, 55 sample sites were surveyed and 2801 ticks were collected, including Rhipicephalus spp, D. marginatus, I. ricinus, Hyalomma marginatum, H. punctata and Ixodes spp, with different collection efforts. All of these ticks were found infected with B. lusitaniae, the main strain of Borrelia found in Portugal. Confirmed pathogenic bacterial strains (B. garinii) were only registered in Mafra and near Coimbra (Soure). Detection of human LB cases was achieved through routine diagnosis in Institute of Hygiene and Tropical Medicine, where several diagnostic techniques were applied. Positive cases were confirmed by immunoblotting (15.5%) and/or amplification of B. burgdorferi s.l. intergenic-spacer of rRNA 5S-23S (rrf-rrl) (28%), with identification of two pathogenic genospecies (B. garinii and B. afzelii), besides B. lusitaniae. Lisboa, Coimbra, Tomar, Viseu and Almada were the main geographic origins of LB positive patients. The main environmental determinants of tick distribution and thus in the epidemiological cycle of Lyme Borreliosis in Portugal were related to climate (temperature, humidity and precipitation) and landscape composition (open areas, mixed and deciduous forests). Landscape structure (e.gfragmentation) was also important in determining tick presence in an area. These environmental factors were used to build risk maps were created for the three main tick-species potentially implicated in the transmission of LB agents in Portugal (I. ricinus, D. marginatus and Rhipicephalus spp). In conclusion, Lyme Borreliosis exists in Portugal and presents a complex epidemiology, as follows: i) besides the known European I. ricinus-vector, other potential tick species were found as vectors for LB spirochetes, being susceptibe to be associated with numerous reservoir hosts (still to investigate) and specific biotopes; ii) an higher diversity of genomic species belonging to B. burgdorferi s.l. complex, which resulted from this large amplitude of both vectors and reservoirs; and iii) a generalized distribution of LB patients, with important infection rates associated with the referred diversity of pathogenic agents, not only with the two more prevalent LB genomic species already recognized in Europe (B. garinii and B. afzelii), as with the recently isolated B. lusitaniae, which induces a clinical status apparently restricted to the Mediterranean basin.
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PAES, RODRIGO DE BARROS. "REGULATING AGENT S INTERACTION: A LAW ENFORCEMENT APPROACH." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2005. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=6662@1.
Анотація:
COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIORNesta dissertação, apresenta-se uma abordagem para regular a interação dos agentes que fazem parte de um sistema multi-agente aberto. Em sistemas abertos, os agentes podem ser não-cooperativos, estão imersos em um ambiente altamente imprevisível e, freqüentemente, os outros agentes que compõem o sistema não são conhecidos a priori. Para algumas classes de aplicações, esta imprevisibilidade não é adequada, podendo levar a falhas de software. Desta forma, é proposta uma abordagem baseada em leis de interação para construir sistemas multi-agentes abertos, onde um controle sobre o comportamento dos agentes é esperado. Propõe-se um modelo conceitual para a especificação da forma como as interações são reguladas em um sistema multi-agente. Este modelo conceitual trata conceitos como cenas, normas e restrições de forma integrada. Além disso, a interação entre os agentes deve ser monitorada e as leis que foram especificadas devem ser aplicadas. Para isto, propõe-se uma linguagem declarativa para a especificação da interação de acordo com os elementos do modelo conceitual e uma infra-estrutura de software que age como mediador das interações garantindo que elas estejam de acordo com as especificações.
In this work, we propose an approach for regulating agents interaction on an open multi-agent system. In open systems, agents are immersed in a highly unpredictable environment, they can be self-interested, and other agents are frequently unknown beforehand. We argue that, in some applications, unexpected behavior may lead to system faults. For this reason, we propose a law enforcement approach to build open multi-agent systems where a certain degree of control over agents behavior is desirable. A conceptual model is proposed to specify how the interactions of an open multi-agent system should happen. This model deals with concepts such as norms, constraints and scenes in a integrated way. We also propose a declarative language that allows the interaction s specification according to the elements that compose the conceptual model, and a software infrastructure that acts as a mediator monitoring and enforcing agents interaction.
3
Matějíček, Petr. "Simulátor BDI agentů a okolního prostředí s překážkami." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2011. http://www.nusl.cz/ntk/nusl-236975.
Анотація:
This term project desribes simulator of multiagent system implementation. It explains basic concepts of agent and multiagent systems. Simulator is implemented as a separated object, which allows to join various models of environment and agents acting in this environment. Evaluation of several types of agent cooperation behavior is in last section of this project.
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Qasim, Irfan. "Equipping Simulation Model (BIOSIM)’s Actors With Multi-agent Intelligence on Cross platforms." Thesis, Högskolan Dalarna, Datateknik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:du-5313.
Анотація:
Thesis is to Introduce an Intelligent cross platform architecture with Multi-agent system in order to equip the simulation Models with agents, having intelligent behavior, reactive and pro-active nature and rational in decision making.
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Dissanayake, Ramani. "Synthetic studies toward asymmetric C-18 analog of antitumor agent, 20(S)- camptothecin." Thesis, Kansas State University, 1997. http://hdl.handle.net/2097/13201.
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Meister, Gabriel T. "Antiviral mechanism(s) of the experimental immunosuppressive agent leflunomide against human cytomegalovirus and polyomavirus." Connect to this title online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1111428519.
Анотація:
Thesis (Ph. D.)--Ohio State University, 2005.Title from first page of PDF file. Document formatted into pages; contains xiii, 127 p.; also includes graphics (some col.) Includes bibliographical references (p. 113-127). Available online via OhioLINK's ETD Center
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CARVALHO, RICARDO ARTUR PEREIRA. "REFLECTIONS ON BOOK DESIGN AND READING: DESIGN CONSIDERING GUARANI HEALTH AGENT´S SCHOOLING LEVELS." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2007. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=10352@1.
Анотація:
COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIORFUNDAÇÃO NACIONAL DE SAÚDE
O design do livro é uma arte invisível? Depende do leitor. Mas como este leitor é considerado pelos designers de livros? Esta questão é o ponto de partida deste estudo, que busca investigar como o designer pode participar do processo de formação de escritores e leitores, compreendendo a inserção do Design, enquanto campo de vocação interdisciplinar, em projetos em que há a predominância do hibridismo, da mescla de vozes e da mescla de identidades.Sabendo que os designers de livro servem a três clientes: autor, leitor e editor, é verificado que apenas autor e editor interferem diretamente no trabalho do designer, enquanto este profissional considera o leitor apenas por uma noção pré-concebida. Desta forma, questiona-se a ausência do leitor nos projetos de design do livro,ao mesmo tempo em que se propõe a noção de Design da Leitura.O estudo considera as teorias que tratam da recepção e mediação da leitura, como em Chartier, e utiliza-se de um exercício etnográfico sobre os encontros presenciais do Projeto de Escolarização dos Agentes de Saúde voltado para o agentes Guarani das aldeias de Itaxi, Araponga, Sapukai e Rio Pequeno, na região de Angra dos Reis e Paraty. A partir da observação das práticas da leitura do grupo Guarani são levantadas questões para pensar uma abordagem que contemple as características destes leitores. Portanto, ao reconhecer a importância do leitor e das mediações, o Design da Leitura contempla também o letramento, ao tentar contribuir tanto para a alfabetização como para a formação das práticas sociais de leitura e escrita.
Is Book Design an invisible Art? How is the reader considered by book designers? These questions are the starting point for this study, which aims at investigating how can a designer contribute to the process of forming new writers and readers. Design is here approached as an interdisciplinary vocational area where hybrid projects occur; encompassing different voices and identities. We work on the assumption that book designers consider three kinds of clients - the author, reader and publisher - and that only author and publisher have traditionally interfered in the designer´s work more directly, while the reader exists more as a pre-conceived notion. By and large, the reader has been disregarded by book designers. We, then, try to propose what we call a Design for Reading or Reading Design. We consider theories that deal with reception and mediation in the reading process. We use theoretians like Roger Chartier and apply them to an Ethnographic exercise carried out at the Schooling Project with Guarani Health Agents in the Native Brazilian Villages of Itaxi, Araponga, Sapukai and Rio Pequeno in the Angra dos Reis and Paraty Regions. By observing the reading process by the Guarani Agents, we raise questions on how to encompass the specific profile of such a reader in the visual project, thereby recognizing the importance of the reader and mediation in the Reading Design. We also consider some aspects of literacy in order to contribute to new reading and writing. social processes.
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McLaughlin, Robert D. "Leveraging an SNMP agent in terminal equipment for network monitoring of U. S. Navy SATCOM." Thesis, Monterey, California. Naval Postgraduate School, 2011. http://hdl.handle.net/10945/5563.
Анотація:
Approved for public release; distribution is unlimited.This research describes and analyzes a United States Navy Satellite Communications (SATCOM) performance monitoring model in providing status information to a network monitoring console to support naval operations. The environment is characterized by potentially adverse conditions that affect satellite performance. Current SATCOM systems are unable to provide performance information to the network's performance monitor because they are not Simple Network Management Protocol (SNMP) enabled and not integrated into the routable network. A network monitoring model defined by sense, decide, and act is central to this study. It represents enhanced monitoring by the subscriber station's monitor console for naval shipboard operations. This model delivers operational and RF environmental information to the SNMP MIB environment so that commonly used SNMP agents can request and send information for sending proper messages to the network's performance monitoring system. The proposed solution is explored through analysis of existing monitoring models together with observations of a tactical networking field experiment, in which equipment at the edge of the network and subscriber's SATCOM terminal is monitored for gathering critical performance details.
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Jasti, Sunitha. "Separation of gliadin peptides for investigation of the injurious agent(s) in gluten sensitive enteropathy." Thesis, This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-06082009-170848/.
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Tegethoff, Katrin, and Sissy Viklund. "The forgotten breed : The emergence of the Middle Manager´s new role as a change agent." Thesis, Linnaeus University, Linnaeus School of Business and Economics, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-5763.
Анотація:
Most organizations of today are more or less influenced by the globalization. This phenomenon has led to that changes belong to the everyday concern of companies in order to be ahead of the competition. Simultaneously, when it comes to discussions about change failures and successes, it mainly is the top management standing in the spotlight. Therefore, the aim of this thesis is to take a glance backstage of organizational changes while focusing on middle management. The purpose of this research is to examine how the middle manager can become a change agent and what contributions this new role can bring to the company. A glimpse on the historical evolution of the middle manager´s role and status helps to identify the underlying causes for the existing stereotype of this management group as well as the reasons for why middle management seems to belong to the ‘forgotten breed’ in organizations. Furthermore, the concept of changes and change management is outlined in order to clarify why changes fail and how those failures can be prevented with the help of a change agent. Based on this theoretical framework, the potential of middle managers acting as change agents is discussed. Additionally, due to the fact that the middle manager’s role as a change agent is not fully recognized yet, an own developed concept is outlined. This model is created as a result of empirical research in terms of interviews with consultants as well as extensive literature studies within this research area. The concept demonstrates how a middle manager can become a change agent and which contributions this new role can bring to the organization. Overall, it can be concluded from the research that it is time for organizations to recognize the potential of middle managers; they are the ones who can make changes happen.
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Tuvhag, Ellinor. "Undersökning av koppars effekt som antibakteriellt agens i tyg." Thesis, Linköpings universitet, Institutionen för medicin och hälsa, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-109410.
Анотація:
Syftet med denna studie var att undersöka den antibakteriella effekten hos ett polyestertyg med tunna invävda koppartrådar. Frågeställningen som skulle besvaras var ifall koppartyget hade en baktericid eller bakteristatisk effekt. Koppartyget är ännu i prototypstadie och om det visar sig ha antibakteriella egenskaper är det tänkt att användas inom klinisk verksamhet för att förhindra bakterietillväxt i sår och andra känsliga lokaler. Koppar är ett essentiellt spårämne, men har också antimikrobiella egenskaper som utövas genom ett brett spektra av mekanismer där skador på cellmembranet är en av de viktigare. Metoderna som användes för att inokulera bakterier på tyget var absorptionsmetoden, där en näringsbuljong innehållande Staphylococcus aureus ATCC 6538 pipetterades på tygproverna, och transfermetoden där tygproverna trycktes mot en agar som racklats med peptonsaltlösning innehållande S. aureus. Totalantalet viabla bakterier per tygprov beräknades efter kort kontakt (<1min) och inkubering (18-24 h vid 37±2°C) genom att räkna viable count. Resultaten efter inkubering visade signifikant skillnad i totalantal bakterier mellan koppartyget och negativ kontroll i tre av fyra försök. Kort kontakt visade tendens till viss antibakteriell effekt. Slutsatsen är att koppartyget skadade och dödade bakterier då de fick inkubera på tyget, medan fler försök behövs för att säkerställa effekten av kort kontakt med koppartyget.The purpose of this study was to test the antibacterial effect of thin copper treads woven into a polyester fabric. The investigation was done by inoculation of Staphylococcus aureus strain ATCC 6538 to the fabric and evaluation of the number of viable cells post exposure by viable count. The issue to be answered was whether the copper fabric had a bactericide or bacteriostatic effect? The fabric is still in prototype stage, and if proven to have antibacterial properties the aim is to use it to prevent bacterial growth in wounds and other vulnerable locations in clinical care. Copper is an essential trace element, but also has antimicrobial properties through a wide range of mechanisms where cell membrane damage is one of the more important. Methods used for inoculation was the absorption method, where a nutrient broth containing S. aureus was pipetted on to the fabric specimens, and the transfer method where the fabric specimens were pressed onto an agar plate that had previously been spread with peptone salt solution containing S. aureus. Total number of bacteria per fabric specimen after short contact (<1 min) and incubation (18-24 h at 37±2°C) was calculated. Incubation showed significant difference in total number of bacteria between the copper fabric and negative control in three of four tests. Short contact showed a tendency of antibacterial effect. The conclusion was that the copper fabric harmed and killed bacteria during incubation but that more records would be needed to be sure about the effects of short contact on bacteria.
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Ioos, Renaud. "Caractérisation génétique de Phytophthora alni Brasier & S. A. Kirk, hybride interspécifique agent du dépérissement de l'aulne en Europe." Nancy 1, 2006. http://docnum.univ-lorraine.fr/public/SCD_T_2006_0105_IOOS.pdf.
Анотація:
Une maladie émergente causant le dépérissement de l'aulne est causée par un complexe de trois taxons du genre Phytophthora (Oomycète) : P. Alni subsp. Alni (Paa), P. Alni subsp. Multiformis (Pam) et P. Alni subsp. Uniformis (Pau). La première partie de cette étude a consisté à mettre au point des outils de détection spécifiques de ces trois taxons. À partir de SCARs générés par RAPD, nous avons défini trois couples d'amorces de PCR dont l'utilisation combinée permet la détection et l'identification spécifique de Paa, Pam et Pau dans différents substrats (plante, eau, sol). Nous avons ensuite étudié la présence et la distribution allélique pour quatre gènes nucléaires contenant des introns sur une collection de P. Alni et d'espèces proches. L'ADN mitochondrial a également été étudié par RFLP et séquençage de deux gènes. Nous avons montré que i) Pau ne semble pas avoir été généré par hybridation, ii) Pam présente deux allèles fortement divergents pour chaque gène nucléaire et résulterait donc d'une réticulation ou d'une autopolyploïdisation, iii) Paa cumule les allèles présents chez Pam et Pau et a probablement été créé par hybridation entre Pam et Pau ou des taxons très proches. De plus, nous avons étudié le profil d'expression des gènes codant pour des élicitines, famille multigénique spécifique du genre hytophthora. L'additivité des profils de Pau et Pam vis-à-vis de Paa a confirmé nos premiers résultats. Enfin, afin d'étudier la variabilité génétique de ces différents taxons, des marqueurs microsatellites ont été isolés chez Paa et caractérisés. Les génotypes obtenus montrent une faible variabilité chez les trois taxons. Ils confirment nos hypothèses quant à l'origine de Paa et suggèrent que Pam est aussi un taxon allopolyploïdeAn emergent disease of alder is caused by a complex of three taxa belonging to the genus Phytophthora (Oomycetes): P. Alni subsp. Alni (Paa), P. Alni subsp. Multiformis (Pam) and P. Alni subsp. Uniformis (Pau). The first part of this study focused on the development of specific detection tools for these three taxa. Based on SCARs generated with RAPD, we designed three PCR primer pairs which can be combined to specifically detect and identify Paa, Pam and Pau in different substrates (plant tissue, water, soil). Second, we studied the occurrence and the allelic distribution for several nuclear single-copy genes containing introns on a wide collection of P. Alni and close species. Mitochondrial DNA was also studied through RFLP and gene sequencing. We demonstrated that i) Pau may not result from a hybridization event, ii) two divergent alleles for each of the nuclear genes are observed in Pam, which suggests this taxon may have been generated by a reticulation or by autopolyploidisation, iii) Paa combines the alleles observed in Pam and Pau and was probably generated by hybridization between Pam and Pau or Pam- and Pau-like taxa. In addition, we studied the expression of elicitin genes, a multigenic family specific to the genus Phytophthora. The cumulative patterns of Pau and Pam in regard with Paa confirmed our first results. Last, in order to study the genetic variability of the different taxa, microsatellite markers were isolated in Paa and characterized. The genotypes we resolved demonstrate a low level of variability for the three taxa. They confirm our hypotheses in regard with Paa origin and suggest that Pam is also an allopolyploid taxon
13
Duvignac, Laurent. "Utilisation de poly(rotaxane)s comme agent structurant pour la préparation de membranes à reconnaissance moléculaire contenant des cyclodextrines." Montpellier 2, 1999. http://www.theses.fr/1999MON20197.
Анотація:
Les cyclodextrines (cds), oligosaccharides cycliques, sont des molecules cages susceptibles de complexer selectivement des molecules organiques suivant des criteres geometriques de taille et de forme. Ces composes ont ete utilises pour realiser des membranes a transport facilite a reconnaissance moleculaire. Les materiaux obtenus possedent de bonnes proprietes de separation pour des molecules analogues (par exemple toluene/ethylbenzene) ou des isomeres geometrique (o-/p-xylene) mais les permeabilites sont faibles lorsque les cds sont repartis aleatoirement dans la matrice membranaire. Les cds peuvent s'enfiler sur un polymere lineaire pour former une structure supramoleculaire appelee pseudo-polyrotaxane. La reaction des extremites avec des groupements encombrants de maniere a eviter la perte des molecules cycliques dans la solution donne naissance a des structures stables polyrotaxanes (prs). L'objectif de ce travail est d'utiliser des prs comme agents structurants de canaux moleculaires dans des materiaux membranaires. Pour cela des cd-prs a base d'-cd et de chaines polyethylene glycol (mw 2000 et 3350 g/mol) ont ete prepares et caracterises, en particulier, par rmn 1h et 1 3c et par une analyse de chromatographie d'exclusion par la taille couplee a un detecteur diffusion de lumiere laser a angles multiples. Il a ete montre que les cd-prs obtenus possedent des structures rigides avec un nombre fixe de cds ne dependant que de la longueur de la chaine. Les cd-prs ont ete incorpores dans une matrice de poly (alcoolvinylique) et le greffage des cds realise par reaction avec un di-isocyanate. Les materiaux obtenus sous forme de films auto-supportes ont ete utilises dans des experiences de pertraction. Les permeabilites des membranes contenant les cds sous une forme pre-orientee sont deux fois superieures a celles obtenues avec des cds reparties au hasard. Les selectivites mesurees pour des solutions aqueuses sources 50/50 ethylbenzene/toluene (2,75) et o-/p-xylene (4,57) sont en accord avec les rapports de constantes de complexation en solution. Elles sont identiques pour les deux types de materiaux.
14
Ray, David C. "Glutathione S-transferase measurement as an index of liver dysfunction after general anaesthesia with a volatile agent in man." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/20134.
Анотація:
On rare occasions, halothane anaesthesia is associated with liver damage. Two forms of toxicity are now recognised - a mild form manifest by increased serum liver enzymes, and a rarer, fulminant form which may be fatal. The historical background, clinical features, morphology and epidemiology of halothane hepatitis are presented, and animal models of halothane hepatotoxicity are described; current perspectives on its aetiology are reviewed. The application of serum enzymes to the recognition of acute liver injury is reviewed, and the limitations of those in current use are described. The measurement of glutathione S-transferase (GST) in plasma by specific radioimmunoassay offers potential for the early detection of drug-induced, hepatocellular damage. The structure, classification, distribution and techniques for measurement of GST are presented, and experience with their use in various liver disorders is explored. The influence of general anaesthesia on several liver enzymes is examined, and the advantage of GST over conventional liver enzymes are discussed. The effects of halothane, enflurane and isoflurane anaesthesia on plasma GST concentration after operation are reported. GST concentration increased 3-6 hours after anaesthesia with halothane and enflurane, and more marked increases were observed at 24 hours in some of the patients who received these agents: GST did not increase at any time in patients who received isoflurane. The incidence of abnormal GST concentrations after anaesthesia with halothane, enflurane and isoflurane directly correlated with the incidence of reported clinical hepatic dysfunction for these drugs.
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Pereira, Ricardo Filipe Amorim. "Relacionando o cumprimento das promessas políticas do(s) partido(s) do Governo com o conceito do agente com poder de veto." Master's thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/17012.
Анотація:
Mestrado em Ciência PolíticaAs promessas políticas são um elemento determinante nas relações entre forças partidárias e eleitores. Apesar de os estudos prévios mostrarem que a maioria das promessas são cumpridas pelos partidos de Governo, esse número varia consoante o tipo de Governo, com incidência maior de cumprimento nos Governos de maioria absoluta de um só partido. Esse facto parece traduzir uma dependência entre a possibilidade do partido enunciatário da promessa de a cumprir e a existência de agentes com poder de vetar a alteração de política pública subjacente. É com base nesta premissa que assenta o presente trabalho exploratório que visa instaurar a noção que o número de agentes com poder de veto existente num sistema político é a condição institucional mais importante e parcimoniosa capaz de tornar previsível a probabilidade de cumprimento das promessas políticas pelo(s) partido(s) do Governo. A outra fase da moeda prende-se com o trabalho de George Tsebelis (2001) Veto Players: How Political Institutions Work e a forma como teorizou a estabilidade das políticas públicas, fenómeno que previu aumentar face a acréscimos no número de agentes com poder de veto. Inferindo a percentagem de promessas cumpridas como um proxy para a estabilidade de políticas públicas – aumenta essa percentagem com a diminuição da estabilidade das políticas públicas – o presente trabalho, em último grau, terá o efeito de possibilitar uma validação à teoria de Tsebelis diferente das habituais uma vez que incide numa variável até aqui não associada: a percentagem de promessas cumpridas pelo(s) partido(s) do Governo.
Political promises are a key element in relationships between party forces and voters. Although previous studies have shown that most of the promises are fulfilled by government parties, this number varies depending on the type of government, with the highest incidence of compliance in the absolute majority of governments of a single party. This fact seems to translate a dependency between the possibility of enunciatee advantage of the promise and meet the existence of agents with power to veto the underlying public policy change. It is based on this premise underlying the present exploratory work that aims to establish the notion that the number of agents with existing veto power in a political system is the most important institutional condition and parsimonious able to make predictable the likelihood of fulfillment of political promises by party(ies) of the Government. The other side of the coin relates to the work of George Tsebelis (2001) Veto Players: How Political Institutions Work and how he theorized the stability of public policy, a phenomenon that predicted face increasing to increase in the number of agents with veto power. Inferring the percentage of promises fulfilled as a proxy for the stability of public policies - increase this percentage to decrease the stability of public policies - this work in last degree, will have the effect of enabling validation to different Tsebelis theory of usual as it focuses on a variable hitherto not associated: the percentage of promises fulfilled by the party(ies) of the Government.
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Silva, Marcos Barros e. "SISTEMA MULTIAGENTES PARA GERENCIAMENTO DE TRÁFEGO URBANO." Universidade Federal do Maranhão, 2005. http://tedebc.ufma.br:8080/jspui/handle/tede/389.
Анотація:
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Previous issue date: 2005-06-28This dissertation is part of TMS project whose objective is the development of a Intelligent Traffic Administration System . TMS has three fundamental functions: (1) Manage the necessary resources to the traffic control; (2) aid in the training of traffic employees; and (3) Accompany the changes of the urban traffic for ends of decision. TMS was conceived to assist the cities that doesn't have systems of traffic control and the others witch has the whole mounted structure with interlinked traffic lights. We show the conception of a system that seeks to assist the needs of traffic administration organs and, at the same time, allow its users to aid in the constant evolution of this management. We will specifically treat an architecture based on agents for our system, the technologies which the system uses and interactions among agents of traffic control. The prototype implemented in this work it allows the automation of the mechanisms of Traffic Administration operation - time of green and red of the traffic lights - turning the changes of semaphored plans the more dynamics as possible.
Esta dissertação é parte do Projeto TMS cujo objetivo é o desenvolvimento de um Sistema inteligente de Gerenciamento de Trânsito. O TMS tem três funções fundamentais : (1) Gerenciar os recursos necessários ao controle do tráfego ; (2) Ajudar no treinamento dos funcionários das companhias de trânsito ; e (3) Acompanhar as mudanças do tráfego urbano para fins de tomada de decisão. O TMS foi concebido para atender desde as cidades que não tem sistemas de controle de tráfego até aquelas que tem todo a estrutura montada com semáforos interligados, etc. Apresenta-se aqui a concepção do sistema que visa atender às necessidades dos órgãos de gerenciamento de trânsito e que, ao mesmo tempo, permita que os seus usuários pudessem auxiliar na constante evolução do mesmo. Trataremos especificamente da arquitetura baseada em agentes proposta para o sistema, as tecnologias que o fundamentam e apreendemos as interações entre agentes de controle de trânsito. O protótipo implementado neste trabalho permite a automação dos mecanismos de funcionamento de Gerenciamento de Trânsito tempo de verde e vermelho dos semáforos - tornando as mudanças de planos semafóricos as mais dinâmicas possíveis.
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Larke, Sylvia Phillipine. "Access, barriers to participation and success amongst mature adult students at a Technical and Vocational Education and Training (TVET) college in the Western Cape." University of the Western Cape, 2021. http://hdl.handle.net/11394/8453.
Анотація:
Magister Educationis - MEdInsights into the experiences of students at TVET colleges can inform policies and practices. This paper focuses on an investigation into students’ experiences of access, and barriers to participation, and success at a TVET college in the Western Cape. I mainly used the theories by Margaret Archer (2003), Anthony Giddens (1979; 1984), Albert Bandura (1989; 2001; 2006), Steven Hitlin and Glen H. Elder (2006), Kjell Rubenson and Richard Desjardins (2009), and K. Patricia Cross (1981) related to structure and agency to analyse my data. Data was collected from interviews with the exit level students at a TVET college who are registered for a National Certificate (Vocational) programme. The evidence of this qualitative research revealed that students experience several institutional, dispositional and situational barriers, but find ways of overcoming these in order to complete their studies successfully. Findings show that elements of ‘agency’ such as ‘intentionality’ ‘forethought’ and self-reflectiveness are prevalent in the ways that students overcome barriers. The findings further revealed that the majority of participants accessed vocational education at a TVET college to improve their lives with the desire and intention to study further. This study generally suggests that intentionality and resilience, amongst other factors, are important elements of agency and are used to explain and interpret the positive relationship between agency, barriers to participation and success.
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Janovský, Lukáš. "Multiagentní simulace - státní zásahy do trhu s nájemními byty." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-114153.
Анотація:
The thesis focuses on the use of multiagent systems to model the rental housing market. At first the aim was to create the simulation, which would bring a new perspective on the development of the entire market. For this purpose I selected a relatively young methodology titled Agentology, which was subjected to the criticism of a model after finishing the model. That was a secondary principal objective of this thesis. The work is divided into two parts. In the first theoretical part the rental housing market is described and there are discussed the most important factors affecting its state. Simultaneously the chapter describes the most significant State interventions into the market, as we know them from the official housing policies. In the next stage the reader is made familiar with the basic principles of multi-agent modeling. In this chapter there is also an overview of selected methodologies of multiagent systems and one of them is selected and applied in further phases of this work. The second part refers to the multi-agent model. Using the Agentology methodology market model is assembled. The methodology accompanies all stages of model development from the task formulation, through conceptual and technological level to the final evaluation. This work strictly adheres to the methodology and all its recommendations. In the end, the result represents a model whose functionality has been verified by analyzing the output data. Finally the thesis deals with criticism of the Agentology methodology. This criticism is a result of experience gained from previous development. It concerns evaluation of concrete steps and also of methodology as a whole in terms of admittance, integrity and practicality.
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Dubinová, Petra. "Zplyňování biomasy v kyslíkové atmosféře." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-400508.
Анотація:
Biomass gasification using air with addition of oxygen can be the right way to increase the quality of the syngas produced. This thesis aims to characterize the gasification process using oxygen-enriched air and verify its effect on the gas. The theoretical part deals with description of the technology with an emphasis on various gasifying agents and different possibilities of increasing gas quality. The practical part contains the results of measurements on the atmospheric fluidized bed reactor and their evaluation. The experiment was performed with various oxygen enrichment taking into account the capabilities of the equipment used.
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Daphney, Cedrick M. "The Fate and Transport of Chemical Warfare Agent Simulants in Complex Matrices." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/chemistry_theses/13.
Анотація:
Experiments to determine the fate and transport of the chemical warfare agent (CWA) simulants diisopropyl fluorophosphate (DIFP), O,S-diethyl methylphosphonothioate (OSDEMP), and 2-Chloroethyl ethyl sulfide (CEES) exposed to complex matrix systems are reported here. The aforementioned simulants were used in place of O-isopropyl methylphosphonofluoridate (GB), O-Ethyl S-(2-diisopropylaminoethyl) methylphosphonothiolate (VX), and Bis (2-chloroethyl) sulfide (HD), respectively. At ambient temperature, simulant pH (2.63 to 12.01) and reaction time (1 minute to 24 hours) were found to have significant influence on the recovery of simulants from charcoal, plastic, and TAP (butyl rubber gloves) in aqueous media. Buffer systems used included, phosphate, acetate, borate, and disodium tetraborate. Organic extractions were carried out using a 90:10 (v/v) dichloromethane / 2-propanol solution. All extracts were analyzed with a gas chromatograph equipped with flame ionization and flame photometric detectors (GC-FID-FPD). The FPD was used to determine the amount of simulant recovery.
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Mathema, Najma. "Predicting Plans and Actions in Two-Player Repeated Games." BYU ScholarsArchive, 2020. https://scholarsarchive.byu.edu/etd/8683.
Анотація:
Artificial intelligence (AI) agents will need to interact with both other AI agents and humans. One way to enable effective interaction is to create models of associates to help to predict the modeled agents' actions, plans, and intentions. If AI agents are able to predict what other agents in their environment will be doing in the future and can understand the intentions of these other agents, the AI agents can use these predictions in their planning, decision-making and assessing their own potential. Prior work [13, 14] introduced the S# algorithm, which is designed as a robust algorithm for many two-player repeated games (RGs) to enable cooperation among players. Because S# generates actions, has (internal) experts that seek to accomplish an internal intent, and associates plans with each expert, it is a useful algorithm for exploring intent, plan, and action in RGs. This thesis presents a graphical Bayesian model for predicting actions, plans, and intents of an S# agent. The same model is also used to predict human action. The actions, plans and intentions associated with each S# expert are (a) identified from the literature and (b) grouped by expert type. The Bayesian model then uses its transition probabilities to predict the action and expert type from observing human or S# play. Two techniques were explored for translating probability distributions into specific predictions: Maximum A Posteriori (MAP) and Aggregation approach. The Bayesian model was evaluated for three RGs (Prisoners Dilemma, Chicken and Alternator) as follows. Prediction accuracy of the model was compared to predictions from machine learning models (J48, Multi layer perceptron and Random Forest) as well as from the fixed strategies presented in [20]. Prediction accuracy was obtained by comparing the model's predictions against the actual player's actions. Accuracy for plan and intent prediction was measured by comparing predictions to the actual plans and intents followed by the S# agent. Since the plans and the intents of human players were not recorded in the dataset, this thesis does not measure the accuracy of the Bayesian model against actual human plans and intents. Results show that the Bayesian model effectively models the actions, plans, and intents of the S# algorithm across the various games. Additionally, the Bayesian model outperforms other methods for predicting human actions. When the games do not allow players to communicate using so-called “cheap talkâ€, the MAP-based predictions are significantly better than Aggregation-based predictions. There is no significant difference in the performance of MAP-based and Aggregation-based predictions for modeling human behavior when cheaptalk is allowed, except in the game of Chicken.
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Kati, Efraim. "Fault-tolerant approach for deploying Server Agent-based Active Network Management (SAAM) server in Windows NT environment to provide uninterrupted services to routers in case of server failure(s)/." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2000. http://handle.dtic.mil/100.2/ADA378563.
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FARIAS, Luciana Fortes. "Sistema multiagente para monitoramento ambiental do Complexo Portuário da Ilha de São Luís-Maranhão." Universidade Federal do Maranhão, 2009. http://tedebc.ufma.br:8080/jspui/handle/tede/1815.
Анотація:
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This work is discussed the conceptual model of a multi-agent system for environmental monitoring with the use of biomarkers of aquatic organisms present in the port complex of São Luís-Maranhão-Brasil, second most important in the country in cargo handling. Located in the São Marcos Bay, this complex have an estuarine ecosystems which have suffered attacks in the current process of economic development, caused by intense port handling, dumping of ballast water and washing the vessels, overfishing, introduction of exotic species in the middle pollution in urban and industrial effluents, subject to severe environmental impacts that should be monitored. Methodologically, the modeling of the monitoring solution, we used the existing environmental conditions and aquatic life caught in two different sites of the port complex, the first in a potentially contaminated area and the second in a contamination-free (control), proposing the creation of a network of sensors in these locations. Invest conceded data by Carvalho-Neta (2007) whose research includes to catch fish in these perimeters, then submitting them for laboratory analysis to measure the enzyme activity of glutathione S-transferase (GST) and Catalase (CAT), the result was processed and recorded in bio-ontology . The core of the solution of Multi-agent system is based on the results derived from the biochemical analysis of GST, inspiring the modeling software agent that simulates the behavior of this enzyme. The solution also includes an application running on mobile devices that makes the collection of environmental variables in the selected points, validates them and makes the inference of those who could not be collected. Multi-agent System for Environmental Monitoring of the Port Complex of the Island of São Luís-Maranhão- Brasil, therefore, is made up of the bio-ontology, sensor networking, mobile application collection and inference of data from environmental conditions, software agents to simulate biochemical analysis, calculation of GST activity and other staff related to the maintenance and security of the SMA.
Nesta dissertação é discutido o modelo conceitual de um sistema multiagente para monitoramento ambiental com uso de marcadores biológicos de organismos aquáticos presentes no complexo portuário de São Luís-MA, segundo mais importante do país em movimentação de carga. Situado na Baía de São Marcos, esse complexo possui um dos ecossistemas estuarinos que mais têm sofrido agressões no atual processo de desenvolvimento econômico, provocadas pela intensa movimentação portuária, despejo de água de lastro e lavagem dos navios, pesca predatória, introdução de espécies exóticas no meio, poluição por efluentes domésticos e industriais, sujeitando o ambiente a fortes impactos ambientais que devem ser monitorados. Metodologicamente, na modelagem da solução de monitoramento, utilizou-se o registro das condições ambientais e de organismos aquáticos capturados em dois pontos distintos do complexo portuário: o primeiro, em uma área potencialmente contaminada e o segundo em uma livre de contaminação (controle), propondo-se a criação de uma rede de sensores nesses locais. Empregou-se dados cedidos por Carvalho-Neta (2007) cuja pesquisa contou com a captura de peixes nesses perímetros, submetendo-os posteriormente a análise laboratorial para medição da atividade enzimática da Glutationa s- Transferase (GST) e Catalase (CAT), tendo todos os resultados processados e registrados em bio-ontologia. O núcleo da solução do Sistema Multiagente baseia-se nos resultados oriundos da análise bioquímica da GST, inspirando a modelagem de agente de software que simula o comportamento desta enzima. Todos esses dados foram registrados em bio-ontologia. A solução contempla também uma aplicação executada em dispositivos móveis que realiza a coleta das variáveis abióticas nos pontos selecionados, valida-as e realiza a inferência daquelas que não puderam ser coletadas. O Sistema Multiagente para Monitoramento Ambiental do Complexo Portuário da Ilha de São Luís, portanto, é constituído pelo conjunto da bio-ontologia, rede de sensores, aplicação móvel de coleta e inferência de dados das condições do meio ambiente, agentes de software para simulação de análise bioquímica, cálculo da atividade da GST e outros agentes relacionados à manutenção e segurança do SMA.
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Kiš, Miroslav. "Činnost realitního makléře v praxi." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-233208.
Анотація:
After a year 1989 with undid market with realty thereby so make entrance new entrepreneurial line thereby is mediation sales and services at sale, purchase, or lease immovables, that have mediating real estate agent´s broker. My diploma thesis with name ,,Activity real estate agent´s broker practically" have as one's task valorize activity real estate agent´s broker in market, system order his activity and these activities then teamed with time and economic heftiness. This work I apportioned into two parts. Theoretic with behind-go region, that have go in for real estate agent´s broker responsible position and about that should have survey. e.g. law delimitation immovables, problems living, market with realty, real estate agent´s activity et. In practical parts is described activity real estate agent´s ,,franchis" offices RE-/MAX and real sale immovables v Českych Budejovicich. I reviewed progress sales immovables and time and economic delimitate heftiness business.
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Kullberg, Helena. "Vad ska jag göra som specialpedagog? : En materiell-diskursiv analys av specialpedagogers uppdrag och yrkesroll i ett skolområde." Thesis, Högskolan Kristianstad, Fakulteten för lärarutbildning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-20827.
Анотація:
Specialpedagogens uppdrag och yrkesroll har i många år uppmärksammats i forskningen, främst i förhållande till speciallärarens uppdrag och yrkesroll för att belysa likheter och skillnader. Denna studie har en ambition att bidra till att belysa vad som påverkar utformningen av en specialpedagogs uppdrag och yrkesroll. Studien är kvalitativ och utgår ifrån Karen Barads teori om agentisk realism där både mänskliga och icke-mänskliga kroppar (performativa agenter) påverkar föreställningar kring t.ex. specialpedagogens uppdrag och yrkesroll. Materia så som t.ex. styrdokument, utbildning mm och språk är starkt sammankopplade i den verklighet som specialpedagogen verkar i och därför bygger studien på en materiell-diskursiv analys. Syftet med denna studie är att åskådliggöra och identifiera vilka performativa agenter som påverkar hur specialpedagogens uppdrag och yrkesroll utformas i grundskolorna i ett skolområde. Metoddelen bygger på en brevmetod samt semistrukturerade intervjuer med speciallärare, specialpedagoger, rektorer och en skolområdeschef i ett skolområde. För att tydliggöra vilka performativa agenter som äger agens i bearbetningen har ett analysschema skapats utifrån uppdrag respektive yrkesroll. I analysschemat för uppdraget har de performativa agenterna kategoriserats utifrån en figur som jag har skapat för att tydliggöra uppdraget. Resultatdelen visar på hur uppdrag respektive yrkesroll presenteras av specialpedagoger, speciallärare, rektorer samt skolområdeschef och pekar på att det förekommer ett stort antal performativa agenter varav rektorns kompetens, rektorns beslut, verksamhetens behov och specialpedagogens kunskap och kompetens har stor betydelse i utformningen av specialpedagogens uppdrag och yrkesroll. Avslutningsvis diskuteras vilken betydelse de performativa agenterna har för utformningen av specialpedagogens uppdrag och yrkesroll samt hur det specialpedagogiska stödet utformas i en organisation. Men även hur figuren som använts kan vara en tydlig modell att använda för att analysera specialpedagogens uppdrag i förhållande till elevhälsoteamets hälsofrämjande, förebyggande och åtgärdande arbete i skolorganisationen d.v.s. som en del i skolutveckling.The special educator´s mission and professional role have for many years been noticed in the research, mainly in relation to the special teacher´s mission and professional role to highlight similarities and differences. This study has an ambition to help illuminate what influences the design of a special educator´s mission and professional role. The study is qualitative and is based on Karen Barad´s theory of agentic realism where both human and non-human bodies (performative agents) influence perceptions about, for example the special educator´s mission and professional role. Matter and language are strongly interconnected in the reality in which the special educator works and therefore the study is based on a material-discursive analysis. The purpose of the study is to illustrate and identify which performative agents influence how the special educator´s assignments and professional role are designed in primary school in a school district. The method part is based on a letter method and semistructured interviews with specialist teachers, special educators, principals and a school district manager in a school district. In order to clarify which performative agents own agents in the processing, an analysis scheme has been created based on assignments and professional role. In the analysis schedule for the assignment, the performative agents have been categorized on the basis of a figure that I created to clarify the assignment. The results section shows how assignments and professional roles are presented by special educators, special teachers, principals and a school district manager, and points to the fact that there are a large number of performative agents, of which the principals competence, the decision of the principal, the needs of the organization and the knowledge and competence of the special educator are of great importance in the design of the special educator´s assignment and profession. Finally, we discuss the importance of the performative agents for the design of the special educator´s mission and professional role and how the special educational support is designed in an organization. But also how the figure used can be a clear model to use to analyze the special educator´s assignment in relation to the student health team´s health promotion, prevention and corrective work in the school organization, i.e. as part of school development.
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Chaine, Mimosa. "Étude du micro et du meiobenthos algal associés au Dinoflagellé Gambierdiscus toxicus Adachi et Fukuyo, agent causal princeps de la ciguatera, par la méthode des substrats neufs artificiels (atoll de Mururoa, Polynésie française)s." Montpellier 2, 1987. http://www.theses.fr/1987MON20268.
Анотація:
Experience montrant une succession de peuplements algaux et faunistiques pendant les treize mois de colonisation. L'analyse des donnees n'etablit pas de correlation entre la presence de g. Toxicus, la densite et les fluctuations des parametres du milieu. Une correlation nette est mise en evidence entre l'accroissement de la population de g. Toxicus et le developpement de l'algue rouge melobesia farinosa, a la surface de laquelle il adhere et qui, de ce fait, joue le role d'algue-support
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Mederly, Peter. "Tvorba hudby počítačem." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2011. http://www.nusl.cz/ntk/nusl-237019.
Анотація:
The main goal of this thesis is the analysis, design and implementation of a new system, which would be able to generate music in real-time, based on terrain data or any raster image. The thesis deals with history of development of various attempts to formalize musical composition and presents contemporary approaches to its algorithmic creation. Technique of constraint programming is explored as well, because it is suitable also for automatic composition, and it is a part of implemented solution. Application components (interface, generator, music core and sound unit) and their interactions are examined in more detail. All approaches used for generating music are described in depth and, moreover, they are supported by many pictures and practical examples. Musical outputs are tested and results of these tests outline strengths, weaknesses and also inner possibilities of the designed system. Conclusion summarises author's contribution to the field of computer generated music and reveals possible prospects for application usage and its extensions.
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LAIB, TAOUES. "Une nouvelle strategie pour la synthese totale d'alcaloides cyclopeptidiques : syntheses totales de la sanjoinine g1 et de la mauritine a. application de la reaction de s nar a la synthese de modeles de l'ustiloxine d, agent antimitotique." Paris 11, 1999. http://www.theses.fr/1999PA112335.
Анотація:
Les alcaloides cyclopeptidiques appartiennent a une famille de produits naturels macrocycliques constitues d'une chaine polypeptidique fermee par une liaison ether aryl-alkyl. Ces composes basiques constituent a eux seuls une tres grande famille de produits naturels. Malheureusement, les proprietes biologiques sont encore mal connues et toutes les syntheses realisees jusqu'a present, selon diverses strategies, sont peu satisfaisantes par manque d'une bonne methode de macrocyclisation. Une nouvelle methode de macrocyclisation basee sur la reaction de s nar intramoleculaire permettant de former la liaison ether aryl-alkyl a ete mise au point lors de ces travaux pour la synthese de macrocycles a 14 chainons (tres difficiles a obtenir). Nous avons ensuite applique cette methode a la synthese totale de la sanjoinine g1. Dans le cadre de cette synthese, un nouveau synthon chiral, le d-n, n-dibenzylserinal (otbdms) a ete developpe et applique a la synthese d'amino-diols enantiomeriquement purs et a la synthese de la (2s, 3s)--hydroxyleucine. De plus, nous avons developpe une synthese chimioenzymatique de 2-amino-1-aryl-alcools chiraux tels que le (r) 2-amino-1-aryl-ethanol en demontrant un remarquable effet de co-solvant sur l'enantioselectivite de l'enzyme hle. Apres ces bons resultats, nous nous sommes ensuite interesses a la synthese totale de la mauritine a, autre produit naturel appartenant a une autre classe d'alcaloides cyclopeptidiques a 14 chainons. Nous voulions montrer que dans le cas de la mauritine a, contenant une -hydroxyproline, la macrocyclisation par s nar serait beaucoup plus facile a realiser que dans le cas de la sanjoinine g1 car la proline favoriserait le repliement de la molecule et ainsi la cyclisation. Cette hypothese a bien ete confirmee par les resultats. Enfin, nous avons aussi applique la reaction de s nar a la synthese de deux modeles simplifies de l'ustiloxine d (mycotoxine antimitotique), metacyclophane a 13 chainons contenant aussi une liaison ether aryl-alkyl endocyclique.
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Polomska, Marta Ewa. "Towards a total synthesis of mensacarcin." Doctoral thesis, [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=976248018.
30
Benboudjema, Louisa. "Clonage des gènes dont l'expression est modifiée lors de l'infection expérimentale de la souris par la tremblante du mouton." Paris 5, 1999. http://www.theses.fr/1999PA05S021.
Анотація:
Les encéphalopathies spongiformes transmissibles (EST) sont des maladies neurodégénératives caractérisées par une spongieuse, une réaction gliale (astrocytaire et microgliale) et une perte neuronale. En dépit des progrès réalisés dans la détermination du rôle clé de la protéine prion PRP, de nombreuses questions restent a préciser sur les mécanismes moléculaires impliqués dans le développement de la maladie et notamment le déclenchement de la réaction gliale et la dégénérescence des neurones. La forme modifiée de la PRP semble être directement impliquée dans l'induction de ces processus. L’objectif principal de cette étude a été de caractériser par MRNA differential display les gènes cellulaires dont le niveau d'expression est modifié dans un modelé d'infection expérimentale bien établi, la tremblante (SCRAPIE) inoculée a la souris. Nous avons observé la surexpression de 9 transcrits dont 5 correspondent à des ARNMS qui n'ont jamais été impliques dans les maladies à prion (Cathepsine S, chaine CLQB du complément, apolipoproteine D, SCRG-1 ET SCRG-2). Le messager SCRG-1 (scrapie responsive gene-1) est exprimé dans les cellules d'origine gliale et neuronale et code une protéine putative inconnue de 98 acides aminés potentiellement membranaire et/ou secrétée. La séquence de la protéine SCRG-1 est tres conservee entre la souris et l'homme (82% d'homologie). L'analyse cinétique montre que la surexpression de SCRG-1, de la cathepsine s et de CLQB coïncide avec la surexpression précoce de marqueurs de l'activation astrocytaire (GFAP) et microgliale (F4/80). Par ailleurs, les gènes de réponse a la tremblante expérimentale que nous avons identifiés présentent également une augmentation de leur taux d'expression dans le cerveau de souris infectées par l'agent de l'ESB. Ainsi, l'augmentation de ces gènes dans les deux modèles expérimentaux suggère que la réponse de l'hôte constitue un élément essentiel dans le processus conduisant aux lésions du tissu cervical.
31
Tomečko, Lukáš. "Hra s agenty na bázi umělé inteligence." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2020. http://www.nusl.cz/ntk/nusl-417296.
Анотація:
The goal of this project is to create a 2D action strategy videogame, featuring intelligent enemies. The architecture design is based on techniques and patterns used in game industry. Game is written in C++, SFML library is used for graphics and inputs, Box2D library takes care of physics. Enemies' artificial intelligence applies standard algorithms used in videogame industry. Human players and metrics are used for evaluation of final game and enemies' intelligence.
32
Pažmová, Kristína. "Právní postavení jednatele společnosti s ručením omezeným." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-10338.
Анотація:
The thesis is describing agent in limited liability company. First part is about the company in general, second about the steps that has to be taken before becomming and agent and also how the post can be disolve and then main part of the thesis is focused on the rights and obligations of an agent.
33
MAININI, ALESSANDRA. "Saggi in economia dell'informazione." Doctoral thesis, Università Cattolica del Sacro Cuore, 2009. http://hdl.handle.net/10280/504.
Анотація:
Questa tesi è una raccolta di tre articoli riguardanti l’economia dell’informazione. Il primo articolo riguarda i possibili effetti negativi delle elezioni sul benessere degli elettori. Infatti, il controllo ottimo nei confronti di un politico dipende in modo non banale dalla relazione tra effetto disciplinante, effetto di selezione e effetto di riduzione della rendita. Il risultato è che un eccessivo controllo nei confronti di un politico può ridurre il benessere sociale. Il secondo articolo analizza un modello di competizione elettorale nel quale l’abilità del politico è sconosciuta anche al politico stesso oltre che agli elettori. L’analisi è in tempo continuo e sviluppata mediante tecniche di programmazione dinamica e di filtraggio. Le credenze sull’abilità vengono aggiornate secondo la regola di Bayes tramite l’osservazione del processo diffusivo che descrive il valore del settore pubblico. Il politico trae utilità da una rendita che è però inferiore in presenza di una scadenza elettorale. Il terzo articolo descrive una relazione principale-agente in tempo continuo dove l’output è rappresentato da un processo diffusivo il cui drift è determinato dallo sforzo dell’agente, che il principale non osserva, e dall’abilità dell’agente, che non è osservata nemmeno dall’agente stesso. Vengono analizzati sia gli incentivi espliciti dati dal contratto che gli incentivi impliciti legati ai career-concerns. L’analisi è sviluppata in tempo continuo; vengono applicate tecniche di programmazione dinamica e di filtraggio.This thesis is a collection of three essays about information economics. The first essay studies the possible negative effects of elections on voters’ welfare. In fact, the optimal control of politicians depends on the interplay of disciplining, selection and rent-shrinking effects in a non-trivial way. We show that too much control on the politician may reduce social welfare. The second essay studies an agency model of electoral competition where the incumbent’s ability is unknown to the voters as well as to the politician herself. The analysis is developed in a continuous-time stochastic framework using dynamic programming techniques. Competence is unobservable to everyone and learned over time in a Bayesian fashion through the observation of the value of the public sector. Politicians can divert resources being in office thus reducing the economy wealth but this rent is lower (all other things the same) with an electoral constraint. The third essay describes a continuous-time principal-agent model in which the output is a diffusion process whose drift is determined by the agent’s unobserved effort and by manager’s competence (it is assumed symmetric information about it). We study separately both explicit incentives arising from the contract and implicit incentives arising from career concerns.. All the analysis is developed in a continuous-time stochastic framework; we apply dynamic programming and filtering techniques.
34
Palanová, Veronika. "Experimentální studium a teoretické modelování transdermálního transportu aktivních látek z gelových matric." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2016. http://www.nusl.cz/ntk/nusl-240533.
Анотація:
This diploma thesis deals with design and experimental study of transdermal transport of pharmaceutically active agents from gel matrices, which contain humic substance in its structure. A model absorption membrane was represented by the skin of pig´s earlobes. The study of the release of active substances and Lignohumte was performed due to the vertical diffusion cells. The amount of released humic substance was characterized by UV-VIS method and the amount of released active agent from gel matrix was determined by HPLC-DAD. The most interesting finding of this diploma thesis was that Lignohumate enhances transdermal transport of active agents and supports their release from gel samples to the particular environment.
35
Válek, Lukáš. "Rozhraní pro propojení strategických her s multiagentními systémy." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2019. http://www.nusl.cz/ntk/nusl-403186.
Анотація:
This thesis is focused on design of framework for creation an articial opponents in strategy games. We will analyze different types of strategy games and artificial intelligence systems used in these types of games. Next we will describe problems, which can occur in these systems and why agent-based systems makes better artificial opponents. Next we will use knowledge from this research to design and implement framework, which will act as support for creating an artificial intelligence in strategy games.
36
Salmon, Mahutin Vianney. "Le cholestérol comme agent cryoprotecteur pour la congélation des semences animales." Doctoral thesis, Université Laval, 2015. http://hdl.handle.net/20.500.11794/26009.
Анотація:
Parce que le cholestérol spermatique influence la résistance des spermatozoïdes à la congélation, nous avons émis l’hypothèse que les spermatozoïdes supplémentés en cholestérol exogène subiraient moins de dommages pendant la cryoconservation améliorant leur pouvoir fécondant après décongélation. Etant insoluble, le cholestérol est incorporé dans la méthyl β-cyclodextrin formant un complexe hydrosoluble, cholestérol lié à la cyclodextrine (CLC). Cette étude à montré que le traitement CLC, dans un dilueur de lait écrémé, améliore la cryorésistance de la semence de bouc en augmentant le niveau de cholestérol spermatique, responsable de la résistance des spermatozoïdes au choc au froid et au stress osmotique, sans affecter la capacitation induite in vitro après décongélation. Par insémination artificielle, les semences ayant subient une augmentation de cholestérol exogène ont montré un meilleur taux de fertilité et de prolificité in vivo par rapport à la semence non traitée. Ces observations suggèrent que le traitement CLC pourrait être utilisé pour améliorer la fertilité des troupeaux et mérite des explorations chez d’autres espèces. Evaluer l’efficacité du CLC sur la cryorésistance de la semence de bélier nous a permis de montrer que le traitement CLC est plus efficace dans un dilueur de lait écrémé par rapport à un dilueur de jaune d’œuf commercial. Toutefois, cette amélioration de la qualité spermatique post-dégel n’est pas suffisante pour induire une augmentation de la fertilité in vivo, suggérant la nécessité d’optimiser le protocole de congélation ou une adaptation du protocole d’insémination. Cependant, combiner le traitement CLC au tréhalose (un cryoprotecteur externe) n’a pas montré d’effet synergique sur l’amélioration de la qualité spermatique post-dégel. Finalement, pour amorcer un transfert technologique nous avons montré que le traitement CLC permet de conserver la qualité spermatique de la semence de bouc en présence de plasma séminal, dont le retrait était recommandé en raison de son effet délétère. De plus, le traitement CLC permet le maintain de la qualité de la semence bouc conservée en frais pendant 24 h à 5°C avant congélation facilitant son transport de la ferme vers le laboratoire. Ces résultats démontrent que le cholestérol joue un rôle crucial et essentiel dans la cryoprotection des semences animales.Because sperm cholesterol content contributes to their resistance to freezing, we hypothesized that exogenous cholesterol incorporated in sperm reduces cryodamage and thus improves the fertilizing capacity of thawed sperm. Being a lipid, cholesterol is insoluble in aqueous media, rendering difficult to deliver to cells in vitro. Methyl β-cyclodextrin is a carrier molecule that couples to cholesterol to form a water-soluble compound, “cholesterol-loaded cyclodextrin” (CLC) that can transfer the cholesterol into cell membranes. The research within this thesis shows that CLC treatment of goat semen enhances fresh sperm resistance to cold shock and osmotic stress due to the increased cholesterol, involving in sperm cryoresistance in a skim milk-based extender without affecting sperm in vitro capacitation after thawing. A pilot field trial in goats demonstrated that artificial insemination with sperm that underwent increased exogenous cholesterol yielded higher fertility and prolificacy rates in vivo compared to untreated semen. These observations suggest that CLC treatment could be used to improve frozen sperm quality and fertility rate of other species. Using ram sperm, our study demonstrated that CLC treatment was more efficient in a skim milk-based extender compared totraditional egg yolk-based extender. However, in vivo fertility of the ram semen that was cryopreserved in the skim milk-based extender with CLC did not differ from semen that was cryopreserved in egg yolk-based extender without CLC. Further research is warranted to combine CLC with other cryoprotection strategies or to modify the insemination protocol to adequately permit capacitation in vivo. However, using CLC treatment with trehalose, a cell impermeable cryoprotectant, did not demonstrate any synergic effect of the cryoprotectants on thawed sperm quality. Finally, in an effort to develop a protocol for semen cryopreservation that can be accessible to the emerging goat industry in Quebec, a pilot test trial demonstrated that goat sperm treated with CLC are more resistant to exposure to seminal plasma than CLC-free sperm in skim milk-based extender. Additionally, CLC treatment markedly improves the post-thaw quality of the sperm after temporary storage for 24 h prior to processing. Together, these results demonstrated that cholesterol has a fundamental and innovative role in animal semen cryoprotection.
37
Vacek, Lukáš. "Adventure hra s inteligentními spolupracujícími postavami." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2016. http://www.nusl.cz/ntk/nusl-255404.
Анотація:
The goal of this master's thesis is to design and implement framework that can be used for development of agent systems. Framework is implemented in Java and encapsulates JADE library. Framework is used for implementation of adventure game. There are several characters (agents) with specific roles who cooperate and try to achieve their goals.
38
Mattar, Jessy. "Stimulation of the fermentation by pulsed electric fields : Saccharomyces cerevisiae case." Thesis, Compiègne, 2015. http://www.theses.fr/2015COMP2196/document.
Анотація:
L’intégration croissante des procédés innovants comme les ultrasons, les champs magnétiques, et les champs électriques pulsés a pour but d’améliorer et de stabiliser le déroulement des procédés de fermentation. Le champ électrique pulsé (CEP) est un procédé athermique généralement utilisé pour l’inactivation des pathogènes (Barbosa-Cánovas et al., 2001) ainsi que pour l’extraction des composés intracellulaires d’intérêt (El Zakhem et al., 2006a; Vorobiev & Lebovka 2006). Dans ce travail de thèse, nous proposons d’évaluer l’activité microbienne des cellules soumises à un traitement électrique modéré. Un intérêt particulier est apporté à des aspects fondamentaux comme la croissance et le métabolisme des cellules. Sur le plan technologique, le but fondamentale est de mettre en place et optimiser des protocoles de stimulation de microorganismes pour intensifier les bioprocédés. La fermentation de microorganismes stimulés par CEP a montré des cinétiques plus rapides que les levures non traitées. La stimulation de l’activité fermentaire s’est révélée grâce au suivi de la masse du milieu, les solutés solubles, l’absorbance, les sucres... L’optimisation des protocoles de stimulation a permis de réveler deux comportements logarithmique et saturé. Il a été montré une dépendance importante de l’énergie spécifique sur certains aspects physiologiques notamment la taille et le nombre de coloniesThe continually increasing integration of innovative technologies such as ultrasound, magnetic fields, and pulsed electric fields aims to improve and stabilize the course of fermentation processes. The pulsed electric field (PEF) is an athermal process generally used for pathogen inactivation (Barbosa-Canovas et al., 2001) and for the extraction of intracellular compounds of interest (El Zakhem et al., 2006a; Vorobiev & Lebovka 2006). In this thesis, we propose to evaluate the microbial activity of cells subjected to a moderate electric treatment. Special consideration is given to key aspects such as growth and cell metabolism. Technologically, the fundamental purpose is to implement and optimize microorganisms’ stimulation protocols to intensify their bioprocesses. The positive impact of PEF pre-treatment on yeast cells was shown by their faster fermentation kinetics compared to the control. This was proven by monitoring the weight of the ferment, the soluble solutes, the UV absorbance, and sugar consumption profiles. Two behaviors of electrostimulation, “logarithmic” and “saturated”, were revealed by optimization of the stimulation protocols. Finally, a relationship between the growth rate, the size of the colonies and the applied specific energy is deduced
39
Stielau, Anna. "Double agents : queer citizenship(s) in contemporary South African visual culture." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20625.
Анотація:
South Africa claims the most progressive constitution on the African continent, extending protections to all citizens regardless of race, gender, ability or sexual orientation. Much has been published in recent years about the induction of LGBTIQ persons into this inclusive post-1994 human rights framework, often with a particular focus on the role of the state in instituting non-discrimination legislation and promoting equality. This document reflects my belief that South African sexuality scholarship too often presents incorporation into a unified nation-state as the only desirable outcome for queer citizens. By mapping the manner in which sexual difference has been uneasily imagined in national discourses, I argue here that the ideal South African citizen remains a heterosexual citizen presupposed as private, patriotic, familial and reproductive. I posit that when non-normative sexual identities and practices become visible in the public sphere, they risk assimilation into "acceptable" modes of representation produced in accordance with the expectations and responsibilities attending state-sanctioned national membership. In so doing, I assert, these cultural forms mandate a queerness that leaves structural inequalities intact. To look beyond this horizon I choose to explore dissident citizenship forms that intervene in dominant cultural narratives to expand the boundaries of belonging. Specifically, I concern myself with representations of queer subjects in visual culture and the multiple audiences these representations invite.
40
Halamíček, Jan. "Real-time počítačová hra s prvky UI." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2009. http://www.nusl.cz/ntk/nusl-236655.
Анотація:
This work deals with an artificial intelligence problematics in real-time computer games. Goal of this project is a creation of an intelligent computer opponent in a real-time enviroment of a multiagent systems.
41
Agbessi, Sonya. "Caractérisation moléculaire et pouvoir antagoniste de souches de S. mélanosporofaciens, agents potentiels de lutte biologique contre des agents phytopathogènes." Sherbrooke : Université de Sherbrooke, 2002.
42
Agbessi, Sonya. "Caractérisation moléculaire et pouvoir antagoniste de souches de S. mélanosporofaciens, agents potentiels de lutte biologique contre des agents phytopathogènes." Thèse, Université de Sherbrooke, 2002. http://savoirs.usherbrooke.ca/handle/11143/5016.
Анотація:
La souche Streptomyces melanosporofaciens EF-76 est un agent de lutte biologique prometteur et des études antérieures ont montré son aptitude à contrôler la pourriture des racines du framboisier causée par le Phytophthora fragariae var. rubi ainsi, que son aptitude à inhiber la croissance d'une grande variété de bactéries Gram+ et de champignons. Des gènes vraisemblablement impliqués dans la biosynthèse de la geldanamycine ont été isolés chez la souche EF-76. Les évidences expérimentales supportant cette affirmation sont l'identification de la production de geldanamycine comme métabolite secondaire produit par EF-76, la présence parmi les gènes isolés d'une glycosyle transférase impliquée dans la résistance à la geldanamycine et enfin, la corrélation existant entre le phénotype d'une souche mutante sensible à la geldanamycine ne produisant plus l'antibiotique et les délétions qu'elle a subi au sein de ces mêmes gènes. Deux souches recombinantes (FP-54 et FP-60) ont été obtenues par fusion de protoplastes intraspécifique et différaient quant à leurs propriétés antagonistes envers les souches B. cereus ATCC 14579, S. scabies EF-35 et Phytophthora fragariae var. rubi 390. FP-60 avait perdu sa capacité à inhiber la croissance de ces microorganismes alors que FP-54 possédait un plus grand pouvoir d'inhibition de croissance envers ces microorganismes. Alors que FP-60 ne produisait plus de geldanamycine, FP-54 produisait, en plus de la geldanamycine, au moins deux autres composés antimicrobiens absents du surnageant de culture de la souche EF-76. Tout comme la souche sauvage EF-76, FP-54 réduisait les symptômes causés par la gale commune de la pomme de terre mais il n'y avait aucune différence entre les index de la maladie, observés en présence de EF-76 et de FP-54. FP-60 ne possédait aucun effet protecteur contre la gale commune de la pomme de terre. Les résultats obtenus suggèrent que l'antibiose et en particulier la production de geldanamycine par la souche EF-76 est une propriété importante à l'efficacité de cette souche en lutte biologique.
43
Houriez, Catherine. "Les identités professionnelles des agents de conduite de la S. N. C. F." Versailles-St Quentin en Yvelines, 1996. http://www.theses.fr/1996VERSA007.
Анотація:
Pour traiter cette question, nous avons construit notre argumentation en trois parties. Tout d'abord, après avoir défini le groupe des agents de conduite comme un groupe corporatiste, nous étudierons les modifications techniques et organisationnelles qui ont boulversé certaines références défendues par la profession. Nous tenterons ainsi de mesurer les conséquences sur la pratique quotidiene de la conduite. Nous ferons également le point sur les travaux menés antérieurement concernant les agents de conduite et sur les acquis de ces recherches. Dans une deuxième partie, nous nous intéresserons au processus de formation des agents de conduite. Quel est le modèle de formation utilisé par l'entreprise ? Les professionnels en poste jouent-ils un rôle important dans le processus de formation ? Pouvons-nous associer la formation des agents de conduite à un processus de socialisation ? Enfin, après avoir étudié les parcours biographiques des individus interrogés, nous tenterons de définir de manière opératoire le concept d'identité pour qu'il puisse rendre compte de notre travail. Enfin, nous proposerons un modèle des constructions identitaires mises en oeuvre par les membres de notre population.
44
Ochs, Magalie. "Modélisation, formalisation et mise en œuvre d'un agent rationnel dialoguant émotionnel empathique." Paris 8, 2007. http://octaviana.fr/document/13337923X#?c=0&m=0&s=0&cv=0.
Анотація:
Les recherches tendent à montrer que les agents virtuels capables d'exprimer des émotions d'empathie permettent d'améliorer l'interaction humain-machine. De tels agents doivent connaître dans quelles circonstances quelles émotions peuvent apparaître durant l'interaction. Pour ce faire, une analyse exploratoire de situations de dialogues réels humain-machine ayant amené l'utilisateur à exprimer des émotions a été réalisée. Ces résultats ont été étudiés à la lumière des descriptions théoriques des émotions en psychologie cognitive afin d'identifier les types d'émotions pouvant apparaître durant un dialogue humain-machine et leurs conditions de déclenchement. A partir de ces informations, un modèle formel des émotions d'un agent rationnel dialoguant a été construit. Les émotions y sont définies par leurs conditions de déclenchement représentées par des états mentaux particuliers, i. E. Des combinaisons de croyances, d'incertitudes et d'intentions. L'intensité de ces émotions est calculée à partir de ces mêmes attitudes mentales. Cette formalisation permet à un agent rationnel dialoguant de déterminer dans quelles situations durant le dialogue quelle émotion d'empathie envers son interlocuteur il devrait exprimer. Ce modèle formel d'émotions a été implémenté sous la forme d'un module de gestion des émotions pour les agents rationnels dialoguants JSA. Une évaluation auprès d'utilisateurs d'un agent rationnel dialoguant émotionnel empathique a permis de mettre en évidence l'amélioration de la perception qu'à l'utilisateur de l'agent lorsque celui exprime des émotions d'empathieRecent research has shown that virtual agents which express empathic emotions enable to improve the human-machine interaction. Such agents should know in which circumstances which emotion may appear during the interaction. To achieve this goal, an exploratory analysis of real human-machine dialog situations which have lead users to express emotions have been done. The results have been studied in the light of the theoretical descriptions of emotions in cognitive psychology in order to identify the types of emotions that may appear during human-machine dialog and their conditions of elicitation. From this information, a formal model of emotions for a rational dialog agent has been designed. The emotions are defined by their conditions of elicitation represented by particular mental state, i. E. By combinations of beliefs, uncertainties, and intentions. The intensity of these emotions is computed from these mental attitudes. This formalisation enables a rational dialog agent to determine in which dialog situations which empathic emotion it should express. Based on the formal model, a module of emotions for JSA rational dialog agent has been implemented. An evaluation with users of an emotional empathic rational dialog agent has enabled us to highlight the positive effect of such agent on the user's perception
45
Marchand, Geneviève. "Étude des déterminants génétiques de l'antibiose de Pseudozyma flocculosa, un agent de lutte biologique." Thesis, Université Laval, 2008. http://www.theses.ulaval.ca/2008/25435/25435.pdf.
46
Montebelli, Alberto. "Towards navigation without sensory inputs: modelling Hesslow?s simulation hypothesis in artificial cognitive agents." Thesis, University of Skövde, School of Humanities and Informatics, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-906.
Анотація:
In the recent years a growing interest in Cognitive Science has been directed to the cognitive role of the agent's ability to predict the consequences of their actions, without actual engagement with their environment. The creation of an experimental model for Hesslow's simulation hypothesis, based on the use of a simulated adaptive agent and the methods of evolutionary robotics within the general perspective of radical connectionism, is reported in this dissertation. A hierarchical architecture consisting of a mixture of (recurrent) experts is investigated in order to test its ability to produce an 'inner world', functional stand-in for the agent's interactions with its environment. Such a mock world is expected to be rich enough to sustain 'blind navigation', which means navigation based solely on the agent's own internal predictions. The results exhibit the system's vivid internal dynamics, its critical sensitivity to a high number of parameters and, finally, a discrepancy with the declared goal of blind navigation. However, given the dynamical complexity of the system, further analysis and testing appear necessary.
47
Bektesevic, Alisa, Grace Oloya, and Tom Schöblom. "How Nelo´s image is perceived in Germany : An empirical investigation amongst their agents." Thesis, Mälardalen University, School of Sustainable Development of Society and Technology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-6350.
Анотація:
The purpose of this research was to investigate how the German market is segmented and what the German consumers perceive of Nelo’s positioning by assessment of what the Agents corroborate. The insights derived from it points out if Nelo’s image is rightly perceived in the German market.
In this paper a qualitative approach is used. Data collection method used was both interviews and documentation. Telephone interviews were conducted with three different agents operating in southern Germany. The secondary data the authors used were articles and books. Since it is a research based on a qualitative approach, the theories and the findings will be synthesized to make implication regarding the study.
The investigation has shown that the target segment for Nelo in Germany are the middle to high income group in the age 40+, but it is shown that the products offered by Nelo don’t attract this segment in southern Germany. Though product quality is good the design and material used, does not fit with the target customer rendering the brand unknown. Nelo is not well positioned in the target market because it has not been successful in communicating a clear image. To conclude Nelo´s position is not consistent with their image.
48
LEMOS, BEATRIZ. "LASTRO: FREE EXCHANGES IN ART MOBILITY IN ART, IT S FLOWS, AGENTS AND REVERBERATIONS." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2013. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=23676@1.
Анотація:
PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIROCOORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR
PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTS. DE ENSINO
A escrita desta dissertação teve como intuito discorrer sobre as ações do projeto Lastro – Intercâmbios Livres em Arte, entendendo-o como rede de contatos e plataforma de ação para projetos colaborativos. Uma proposta que visa conexões no campo da arte e cultura no contexto América Latina, porém com reverberações além-territórios. Como rede opera em diferentes frentes de trabalho e pensamento, tendo a mobilidade contemporânea como foco de estudo. Esta pesquisa propôs uma ramificação do pensamento sobre mobilidade em formato de cadernos de viagens, aprofundando pontos de vista e abordagens diferenciadas acerca do deslocamento e como este é entendido por artistas, transformando-se em poética. Quatro cadernos que se transmutarão em pequenas publicações via coleção de livros Lastro. Tal trânsito tem como objetivo fomentar projetos editoriais experimentais que atuem como dispositivo questionador e aglutinador. Além disso, tal projeto inaugura o selo editorial Lastro, o que faz nascer mais uma atividade da rede. A realização dessa pesquisa vem auxiliar uma maior compreensão conceitual do Lastro e sua potência política enquanto proposta curatorial rizomática.
The core aim in the writing of this abstract was to discourse on the project named Lastro - Intercâmbios Livres em Arte (ballast –free exchange art) seeing it as an action platform and a network for cooperative projects. A project that seeks the connections of artistic and cultural fields within the Latin-America context, though resounding beyond its limits. As a network it acts in various types of work fronts and thoughts, having a contemporary movability as its study focus. That research has proposed a branching of the thoughts on movability in the shape of travel diaries, deepening points of views and the differentiated approaches regarding movement and how it is understood by artists by shaping it into poetic. Four diaries that will take the format of small publications through the Lastro book collection. The goal of such movement is to promote the experimental publishing projects that may act as a questioning as well as unifying device. Besides, such project also inaugurates the Lastro imprint, and by doing so, we’ll be starting one more activity in its network. The execution of such research intends to enhance the conceptual comprehension of Lastro and its political potentiality as a non-hierarchical curatorship project.
49
Fonteneau, Yannick. "Développements précoces du concept de travail mécanique (fin 17e s.-début 18e s.) : quantification, optimisation et profit de l'effet des agents producteurs." Phd thesis, Université Claude Bernard - Lyon I, 2011. http://tel.archives-ouvertes.fr/tel-00640402.
Анотація:
En prenant comme point d'horizon l'entrée du concept de travail mécanique dans la physique théorique par les ingénieurs-savants du début de 19e siècle (Coriolis et Navier notamment), cette thèse montre la filiation de ce concept vis-à-vis de démarches apparaissant à l'aube du 18e siècle à l'Académie Royale des Sciences de Paris, notamment dans les oeuvres d'Amontons et de Parent. La thèse montre alors comment et pourquoi le concept commence à se développer au premier 18e siècle dans cet environnement, comment il est ensuite repris, enrichi, modifié par Pitot, Bélidor, Desaguliers, D. Bernoulli, et comment au contraire ce concept semble ignoré de savants plus théoriciens tel que D'Alembert. Le rôle de la rupture de la vision statique de la machine semble déterminant. Apparaît alors la forte dépendance de ce concept aux problématiques qu'il permet de résoudre, axées sur la quantification et l'optimisation de l'effet des hommes, des animaux et des machines en situation laborieuse, et leurs comparaisons mutuelles dont l'une des finalités est la recherche du profit économique. L'histoire du concept se donne à voir comme une interface permanente entre mécanique théorique, mécanique pratique, et aspects productifs. On suggère alors que la légitimité du concept tient dans sa pertinence à rendre compte du travail des agents producteurs. Enfin, la thèse s'attache à recréer l'épaisseur du réel derrière les concepts et les problématiques, en montrant ce qu'ils doivent aux stratégies gouvernementales et aux pratiques d'ingénieurs.
50
Nougarède, Romain. "Contrôle de l'initiation de la réplication de l'ADN au cours du cycle mitotique chez la levure "S[accharomyces] cerevisiae"." Montpellier 2, 2000. http://www.theses.fr/2000MON20093.
Анотація:
La levure saccharomyces cerevisiae est l'organisme eucaryote chez lequel les mecanismes de regulation de la replication sont les mieux connus et ou les origines de replication ainsi que de nombreux facteurs necessaires pour l'entree en phase s ont ete identifies. Ces facteurs ont des homologues chez tous les eucaryotes, ce qui suggere que les mecanismes controlant l'initiation de la replication soient conserves, des eucaryotes unicellulaires a l'homme. Mes travaux de these ont concerne principalement l'etude d'une kinase, ddk (dbf4/cdc7), essentielle pour l'initiation de la replication. Nous avons pu montrer que l'activite de cette kinase est regulee par sa sous-unite regulatrice (dbf4), que l'activite culmine lors de la phase s et decroit en g2/m. Nous montrons par ailleurs, que ddk ne peut remplir sa fonction pour la phase s qu'apres activation d'une autre kinase controlant l'entree en phase s (clb-cdk1). Nous avons egalement mis en evidence qu'une partie de la regulation exercee sur dbf4p se faisait par un mecanisme actif de proteolyse des proteines impliquant l'anaphase promoting complexe (apc). La suite logique de ce travail a donc ete de rechercher les substrats de cette kinase (dbf4/cdc7). Nous montrons que cdc45, proteine essentielle pour l'initiation de la replication est phosphorylee par la kinase cdc7 in vitro. L'ensemble de ces travaux apporte des elements nouveaux sur le role de ddk dans cette etape clef du cycle cellulaire qu'est l'initiation de la replication et particulierement sur sa regulation spatiale au niveau des origines.