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Дисертації з теми "Anti-Diabetic Medicines"

Автор: Grafiati

Опубліковано: 7 червня 2025

Оновлено: 2 серпня 2025

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1

Calhoun, McKenzie L. "Novel Anti-Diabetic Medications." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/6885.

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2

Adefuye, Ogheneochuko Janet. "Anti-diabetic and phytochemical analysis of sutherlandia frutescens extracts." Thesis, Nelson Mandela Metropolitan University, 2016. http://hdl.handle.net/10948/3549.

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In Africa, the importance of medicinal plants in folklore medicine and their contribution to primary healthcare is well recognized. Across the continent, local herbal mixtures still provide the only therapeutic option for about 80% of the population. The vast floral diversity and the intrinsic ethnobotanical knowledge has been the backbone of localized traditional herbal medical practices. In Africa, an estimated 5400 of the 60000 described plant taxa possess over 16300 therapeutic uses. Similarly, with a therapeutic flora comprising of approximately 650 species, herbal medical practitioners i

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3

Srijayanta, Sairavee. "Biological and phytochemical studies on some traditional anti-diabetic plants." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367943.

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4

Semaan, Dima. "In vitro anti-diabetic and anti-obesity activities of compounds from the Cuban medicinal plant, Allophylus cominia (L.) Sw." Thesis, University of Strathclyde, 2014. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=24304.

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Based on ethnobotanical information collected from Cuban diabetic patients in Cuba, medicinal plants such as Allophylus cominia (L.) Sw. (A. cominia) was identified as a possible source of new drugs that could be used for the treatment of type 2 diabetes mellitus. Type 2 diabetes mellitus or non-insulin dependent diabetes mellitus (T2-DM) is a chronic disease, and when associated with obesity (a condition known as diabesity) leads to an increase in the risk of a number of comorbidities, e.g. cardiovascular, kidney and liver diseases. A. cominia is a Cuban plant used traditionally by diabetic p

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5

Harris, Cory S. "Anti-diabetic and neuroprotective activities of phytochemicals in traditionally used boreal plants." Thesis, University of Ottawa (Canada), 2008. http://hdl.handle.net/10393/30161.

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This thesis investigated the phytochemistry and pharmacology of boreal plant species used traditionally as treatments for symptoms and complications of diabetes and was completed in collaboration with the Team in Aboriginal Anti-Diabetic Medicine and the Cree of Eeyou Istchee in northern Quebec. Using a novel metabolomic-based approach, we first developed methods of phytochemical analysis to characterize Vaccinium angustifolium extracts and then other medicinal Ericaceae, identifying and quantifying an abundance of phenolic compounds. These methods were then employed to profile the phenolics

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6

Tam, Teresa. "The effects of Cree anti-diabetic natural health products on drug metabolism and cardiomyocytes." Thesis, University of Ottawa (Canada), 2009. http://hdl.handle.net/10393/28230.

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Seventeen Cree anti-diabetic medicinal plant were investigated for their capacity to cause adverse effects when used as alternative or complementary medicine. Two aspects of safety were studied using their extracts: the ability to affect the contraction rate of neonatal rat cardiomyocytes in vitro to determine if the plants can influence the human heart rate, and the ability to interfere with drug metabolism by inhibiting the cytochrome P450 enzymes in vitro. The results suggest that several Cree plants may cause a harmful effect through different mechanisms. The extracts ofW2, W4, W5, and W9

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7

Roostaei, Davoud. "Isolation and characterisation of anti-diabetic pharmacological activities of phytoestrogens and components of Moringa peregrina (Forssk) Fiori." Thesis, London Metropolitan University, 2015. http://repository.londonmet.ac.uk/1141/.

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Diabetes is an endocrine disease characterised by a chronic increase in blood sugar levels caused by a deficiency of insulin production, which leads to type 1 diabetes, or by a loss of tissue response to insulin, which leads to type 2 diabetes. The disease leads to disruption of metabolism, vascular damage and damage to the nervous system, as well as damage to other organs and systems. Type 2 diabetes is becoming more common throughout the world, due to poor nutrition and lifestyle, and genetic background. Efforts have accordingly been increased towards developing and refining treatments as we

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8

Varghese, Della. "Prevalence of Anti-diabetic and Antilipidemic Medications in Children and Adolescents treated with Atypical Antipsychotics in a Virginia Medicaid Population." VCU Scholars Compass, 2013. http://scholarscompass.vcu.edu/etd/491.

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Objective: To determine if the prevalence of anti-diabetic and antilipidemic medication use among children treated with atypical antipsychotics is higher than those not treated with antipsychotics. Methods: Virginia Medicaid beneficiaries (2-17 years) continuously enrolled from August 1, 2010 to July 31, 2011 with at least two prescription claims for atypical antipsychotics were the exposed group. All other subjects during the study period were the non-exposed group. Prevalence of anti-diabetic and antilipidemic medication use in both groups were computed and compared using Chi-square test (α

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9

Van, Huyssteen Mea. "Collaborative research with traditional African health practitioners of the Nelson Mandela Metropole : antimicrobial, anticancer and anti-diabetic activities of five medicinal plants." Thesis, Nelson Mandela Metropolitan University, 2007. http://hdl.handle.net/10948/663.

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The promotion and development of indigenous knowledge pertaining to the traditional African healing system is one of the prime objectives set out by the South African government. Despite excellent research opportunities and funding, the biggest problem with ethnopharmacological research is a lack of interaction with indigenous communities, which tends to dilute the benefits this research has to offer these communities. The primary aim of this study was thus to promote the traditional African healing system through collaborative medicinal plant research with local traditional health practitione

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10

Limaki, Hamidreza Khalatbari. "In-vivo and in-vitro study of mechanism of action of 4 hydroxyisoleucine as an amino acid derived from fenugreek seed with anti-diabetic and properties." Thesis, London Metropolitan University, 2014. http://repository.londonmet.ac.uk/688/.

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Diabetes is a progressive multi-factorial metabolic syndrome with serious short and long term complications affecting many of organs with high increasing prevalence in the world. Using herbs and their derivatives for treating diabetes has a long history in many traditional cultures across the world. Molecules and compounds were isolated from herbs are the basis of many therapeutics which we are using in medicine for treating a variety of health conditions. The seeds of fenugreek, Trigonella foenum graecum, commonly used as a spice in Middle Eastern countries and widely used in South Asia and E

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11

Chiu, Jiun-Yao, and 邱俊耀. "A Recommender System Based on Entropy of Multiple Criteria Decision Making and Domain Ontology-An Example of Anti-diabetic Medicines." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/17780956370371645054.

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碩士<br>朝陽科技大學<br>資訊管理系碩士班<br>99<br>Generally speaking, we have to consider the effect of many factors when making a decision. The recommended system can help user to analyze needs and give suggestions with complex information. Our research focuses on the assistance of medical suggestion for doctors. According to the statistics of Department of Health, diabetes was one of the top ten causes of death in Taiwan in 2009. Therefore, developing an effective treatment for diabetes is very important. The fact is that the amount of diabetes specialists is not enough and not all diabetic patients can be

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12

"Investigations on the anti-diabetic activities of traditional Chinese medicine formulae originally used against diabetic foot ulcer." 2004. http://library.cuhk.edu.hk/record=b5892063.

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Chan Chak Ming.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2004.<br>Includes bibliographical references (leaves 178-202).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>Abstract in Chinese 摘耍 --- p.iii<br>Acknowledgements --- p.v<br>Table of contents --- p.vi<br>List of tables --- p.xii<br>List of figures --- p.xiii<br>Abbreviations --- p.xvi<br>Chapter Chapter 1: --- Introduction --- p.1<br>Chapter 1.1 --- Definition of diabetes mellitus --- p.1<br>Chapter 1.2 --- Classification of diabetes mellitus --- p.4<br>Chapter 1.2.1 --- Type 1 diabetes --- p.4<br>Cha

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13

Ibrahim, Auwal Mohammed. "The in vitro and in vivo anti-oxidative and anti-diabetic effects of some African medicinal plants and the identification of the bioactive compounds." Thesis, 2013. http://hdl.handle.net/10413/11312.

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This thesis examined the in vitro and in vivo anti-oxidative and anti-diabetic activities of five African medicinal plants which are traditionally used for the treatment of diabetes mellitus viz; Ziziphus mucronata, Cassia singueana, Parkia biglobosa, Khaya senegalensis and Vitex doniana. Ethanol, ethyl acetate and aqueous crude extracts of the stem bark, root and leaf samples of each of the plants (a total of 45 crude extracts) were investigated for detailed anti-oxidative activity and the most active crude extract from each plant was selected for further fractionation with solvents of increa

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14

Lo, Hsin-Yi, and 羅欣宜. "Research and Development of Insulin Receptor Targeting Anti-diabetic Drug Based on Experiences of Traditional Chinese Medicine." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/k482vr.

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15

"Investigation of pharmacological anti-diabetic effect on selected traditional Chinese herbs." 2005. http://library.cuhk.edu.hk/record=b5892567.

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by Lam Fung Chun.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2005.<br>Includes bibliographical references (leaves 187-202).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>Abstract in Chinese --- p.iii<br>Acknowledgements --- p.v<br>Table of Contents --- p.vi<br>List of Abbreviations --- p.xiii<br>List of Tables --- p.xvii<br>List of Figures --- p.xviii<br>Publication --- p.xx<br>Chapter Chapter 1 --- Introduction --- p.1<br>Chapter 1.1 --- Epidemiology of Diabetes Mellitus --- p.1<br>Chapter 1.2 --- Definition of Diabetes Mellitus --- p.1<br>Chapter 1.3 --- G

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16

"Pharmacological and phytochemical investigations on selected Chinese herbs with regards to their anti-diabetic activities." 2004. http://library.cuhk.edu.hk/record=b5892121.

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by Lau Chun Hong.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2004.<br>Includes bibliographical references (leaves 179-195).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>Abstract in Chinese 摘要 --- p.iv<br>Acknowledgements --- p.vi<br>Table of Contents --- p.vii<br>List of Abbreviations --- p.xiii<br>List of Figures --- p.xvi<br>List of Tables --- p.xviii<br>Publications --- p.xix<br>Chapter Chapter1 --- Introduction --- p.1<br>Chapter 1.1 --- Epidemiology of Diabetes Mellitus --- p.1<br>Chapter 1.2 --- Definition of Diabetes Mellitus --- p.2<br>Chapter 1.3 -

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17

Malmir, Maryam. "Contribution to the study of Satureja Khuzestanica jamzad leaf as potential herbal medicine." Master's thesis, 2014. http://hdl.handle.net/10451/15890.

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Tese de mestrado, Medicamentos à Base de Plantas, Universidade de Lisboa, Faculdade de Farmácia, 2014<br>Satureja khuzestanica Jamzad parte aérea é uma planta medicina muito popular entre os habitantes nómadas do sudoeste iraniano, sendo usada como anestésico. A composição do seu óleo essencial é já conhecida sendo o carvacrol o seu principal constituinte. Diversos estudos biológicos já foram também já realizados usando o óleo essencial mas são escassos os estudos relativos à qualidade, segurança e modo de ação de preparações aquosas (infuso ou decocto) à base desta substância derivada de plan

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18

CHEN, SAN-YUAN, та 陳三元. "Searching For Anti-Type II Diabetic Medicine From Chinese Herbal Extracts Based On Their Activity To Inhibit Cdk5-Mediated PPARγ phosphorylation". Thesis, 2017. http://ndltd.ncl.edu.tw/handle/jr5qhs.

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博士<br>國立中正大學<br>生命科學系分子生物研究所<br>105<br>Diabetes mellitus is a chronic, debilitating disease that affects every organ system. Over the past decade, because of the global population aging, advanced civilization, and modern lifestyle changes, the number of people with diabetes mellitus has increased dramatically. Thiazolidinediones (TZD) represent a class of synthetic agonistic PPAR ligands which have been used to make the body’s tissues more sensitive to insulin and thus are effective anti-diabetic drugs. Their insulin-sensitizing effects have been shown to come from their ability to inhibit ph

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19

"Investigation on the anti-diabetic effects of selected natural products/Chinese herbs by inhibiting the activity of sodium-glucose cotransporter 2 (SGLT2)." 2012. http://library.cuhk.edu.hk/record=b5549132.

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糖尿病是一種以不正常的高血糖為主要特徵的長期性的糖代謝紊亂疾病。二型糖尿病是常見的糖尿病類型，多於九成的糖尿病病人患有此種類型。各種引起糖尿病的病因最終都會導致血糖過高，並且最終會引起有關眼睛，腎臟，神經和血管系統的併發癥。迄今，糖尿病正影響著大約世界6%的人口，而現在患病率依然在逐年增加。在香港，由於高能量的食和缺乏運動，越來越多的老年人和青年人正在遭受著糖尿病的困擾。糖尿病不是一種致命性的疾病，但是如果沒有採取好的治療控制措施，糖尿病最終會引起一些併發癥，這些併發癥最終會使糖尿病患者走向死亡。高血糖癥不僅是糖尿病的主要特徵，而且也是引起各種糖尿病併發癥的重要因素，在二型糖尿病的治療當中，根據各種病理因素，市場上已經研製出了很多西藥來治療糖尿病。然而，它們都有一些副作用的限制。因此，我們需要通過綜合治療和通過新的途徑研製新的製劑來控制血糖水平，保護病人遠離長期併發癥的困擾。如今，腎臟在血糖平衡中的重要角色已經被很好的認知。在過去的二十年裡，通過減少血糖在腎臟的重吸收來增加尿液中血糖的排出，從而達到降低體內血糖水平的方法已經被提出并認為是治療糖尿病的一直新的途徑。在腎臟中，鈉葡萄糖共轉運體2（SGLT 2）主要負責葡萄糖的重吸收，因此，鈉葡萄糖共轉運體2（SGLT 2）抑製劑被認為是一種有潛質的新型的治療糖尿病的製劑。然而，市場上至今沒有成功研製這種製劑。达格列嗪（dapag

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