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Статті в журналах з теми "Anti-septic"

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Ezzell, Carol. "(Anti-) Septic Strategies." Science News 142, no. 7 (1992): 104. http://dx.doi.org/10.2307/3976671.

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Wang, R., Q. Fang, L. Zhang, et al. "CD28 ligation prevents bacterial toxin-induced septic shock in mice by inducing IL-10 expression." Journal of Immunology 158, no. 6 (1997): 2856–61. http://dx.doi.org/10.4049/jimmunol.158.6.2856.

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Abstract The pathogenesis of septic shock is due mainly to bacterial toxin stimulation of the immune system, resulting in an excessive production of proinflammatory cytokines. TNF-alpha has been implicated as a major mediator in septic shock. Coinjection of D-galactosamine and LPS or staphylococcal enterotoxin B induced a rapid-onset, low-dose form of septic shock syndrome and ultimately led to death. We found that both the septic shock syndrome and death could be prevented by administration of anti-CD28 Ab. The protection induced by anti-CD28 Ab was associated with a decrease in TNF-alpha lev
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Shen, Yuchao, and Ying Cui. "Cholinergic anti-inflammatory pathway confers protective effects in septic shock rats." STEMedicine 5, no. 2 (2024): e191. http://dx.doi.org/10.37175/stemedicine.v5i2.191.

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Background: Septic shock can lead to multiple organ dysfunction. The cholinergic anti-inflammatory pathway is known to prevent organ damage from infection by modulating the inflammatory response. However, the modulatory capacity of cholinergic anti-inflammatory pathways in septic shock remains unclear. Methods: Cecal ligation and puncture (CLP) was used to establish a rat model of septic shock. Bilateral cervical vagal nerve isolation, dual cervical vagotomy, and vagus nerve stimulation (VNS) were used to inhibit or activate cholinergic anti-inflammatory pathways. Tacrine and α-bungarotoxin gr
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Yang, Sumin, Bong-Seon Lee, Changhun Lee, Sae-Kwang Ku, and Jong-Sup Bae. "Anti-Septic Effects of Cudratricusxanthone A Against HMGB1-Mediated Septic Responses." Natural Product Communications 14, no. 6 (2019): 1934578X1985679. http://dx.doi.org/10.1177/1934578x19856793.

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COHEN, J. "Anti-endotoxin immunotherapy in septic shock." Journal of Antimicrobial Chemotherapy 18, no. 4 (1986): 436–39. http://dx.doi.org/10.1093/jac/18.4.436.

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BAUMGARTNER, J. D., and M. P. GLAUSER. "Anti-endotoxin immunotherapy in septic shock." Journal of Antimicrobial Chemotherapy 19, no. 4 (1987): 551. http://dx.doi.org/10.1093/jac/19.4.551.

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Wu, Ji, Zhenhua Wang, Shanling Xu, et al. "Analysis of the role and mechanism of EGCG in septic cardiomyopathy based on network pharmacology." PeerJ 10 (March 9, 2022): e12994. http://dx.doi.org/10.7717/peerj.12994.

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Background Septic cardiomyopathy (SC) is a common complication of sepsis that leads to an increase in mortality. The pathogenesis of septic cardiomyopathy is unclear, and there is currently no effective treatment. EGCG (epigallocatechin gallate) is a polyphenol that has anti-inflammatory, antiapoptotic, and antioxidative stress effects. However, the role of EGCG in septic cardiomyopathy is unknown. Methods Network pharmacology was used to predict the potential targets and molecular mechanisms of EGCG in the treatment of septic cardiomyopathy, including the construction and analysis of protein-
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Gore, David, Lorena Preciado-Llanes, Gary Mills, Andrew Heath, and Robert Read. "In vitro hyporesponsiveness of CD4+ and CD8+ T cells in septic patients with faecal peritonitis (HUM8P.326)." Journal of Immunology 192, no. 1_Supplement (2014): 185.1. http://dx.doi.org/10.4049/jimmunol.192.supp.185.1.

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Abstract The immunological processes behind sepsis are ill defined. Predicting or diagnosing sepsis, based on cellular immune parameters is a research priority. This study quantified differences in peripheral blood mononuclear cell (PBMC) and cytokine levels between septic patients with fecal peritonitis, matched surgical patients (no sepsis) and healthy controls. To assess function, PBMC were stimulated in vitro with anti-CD3±anti-CD28 antibodies. Four days later T and B cell proliferation were measured by CFSE and activation by expression of CD25 and CD69 on T cells and CD86 on B cells. Viab
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Kim, Kyeong-Min, So-Yeon Kim, Tamanna Jahan Mony та ін. "Dracocephalum moldavica Ethanol Extract Suppresses LPS-Induced Inflammatory Responses through Inhibition of the JNK/ERK/NF-κB Signaling Pathway and IL-6 Production in RAW 264.7 Macrophages and in Endotoxic-Treated Mice". Nutrients 13, № 12 (2021): 4501. http://dx.doi.org/10.3390/nu13124501.

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The excessive synthesis of interleukin-6 (IL-6) is related to cytokine storm in COVID-19 patients. Moreover, blocking IL-6 has been suggested as a treatment strategy for inflammatory diseases such as sepsis. Sepsis is a severe systemic inflammatory response syndrome with high mortality. In the present study, we investigated the anti-inflammatory and anti-septic effects and the underlying mechanisms of Dracocephalum moldavica ethanol extract (DMEE) on lipopolysaccharide (LPS)-induced inflammatory stimulation in RAW 264.7 macrophages along with septic mouse models. We found that DMEE suppressed
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González, Celso, Ariadna Luna, Manuel Morales, Janet Sanchez, Claudia Guzman, and Juvenal Granillo. "Statin anti-inflammatory therapy in septic patients." Critical Care 12, Suppl 5 (2008): P26. http://dx.doi.org/10.1186/cc7059.

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Дисертації з теми "Anti-septic"

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Peake, Sandra Lois. "Combination anti-cytokine immunotherapy in an ovine model of gram-negative septic shock." Title page, contents and summary only, 2000. http://web4.library.adelaide.edu.au/theses/09PH/09php3576.pdf.

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Анотація:
Bibliography: leaves 288-336. This thesis examines the role of ant-cytokine monoclonal antibodies (mAb) as an adjunctive treatment in an animal model of septic shock. In particular, the role of combination immunotherapies directed against more than one cytokine is investigated.
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Furebring, Mia. "C5a Receptor Expression in Severe Sepsis and Septic Shock." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5832.

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Hjerdt-Goscinski, Gunilla. "Antibiotic-induced Bacterial Toxin Release – Inhibition by Protein Synthesis Inhibitors." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4692.

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Kimmoun, Antoine. "Impacts hémodynamique et inflammatoire de la modulation de la fréquence cardiaque dans le choc septique." Thesis, Université de Lorraine, 2016. http://www.theses.fr/2016LORR0178/document.

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Introduction : Malgré une réanimation bien conduite, un certain nombre de patients en choc septique présentent une tachycardie persistante. Dans ce contexte, cette élévation de la fréquence cardiaque peut être le reflet d’un certain degré de dysautonomie. L’objectif de cette thèse est d’évaluer, sur un modèle expérimental de choc septique, l’impact d’un ralentissement de la fréquence cardiaque soit par un β-bloquant cardiosélectif aux effets anti inflammatoires (esmolol, travail 1) soit par l’ivabradine, un inhibiteur des canaux if sans effets anti-inflammatoires majeurs en situation aiguë, (t
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Ayub, Qasim. "Prevention of endotoxic shock in mice using anti-tumor necrosis factor-alpha monoclonal antibody." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc798464/.

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Lin, Mei Lan, and 林美蘭. "COX-2 Selective Anti-inflammatory Drugs Aggravated Septic Lung Injury." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/12042516588342275587.

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碩士<br>中國醫藥學院<br>醫學研究所<br>91<br>Acute lung injury (ALI) is a major complication of sepsis, which could leads to the increased susceptibility to pulmonary infection. Nonsteroid anti-inflammatory drugs (NSAIDs) are commonly used clinically for the management of sepsis-related manifestations, including pain, fever, and inflammation. However, their effects on septic lung injury are not recognized. Recent studies revealed that NSAIDs cause apoptosis in several cell types. Our hypothesis was that, during the process of sepsis, the usage of NSAIDs may enhance AM apoptosis and, thereafte
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Chang, Feng-Nian, and 張豐年. "A Study of Anti-septic Calcium Phosphate Coated on 316L Stainless Steel by Electordeposition." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/05639543098889433176.

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碩士<br>大同大學<br>材料工程研究所<br>91<br>Coating bioactive ceramics onto metals was a popular method to resolves the problems of biocompatibility, ion released and fixation of metal implant. But at present, it should not solve the problems; as the coating layer was only a thin film, needed a long-term treatment, and have poor bonding strength. On the other hand, the surface of implant materials should not antibacterial, so that increasing ratio of infect with bacterial. So in our research, 316L stainless steel was selected as the substrate and electrolytically deposition with hydroxyapatit
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Chang, Po-Hsun, and 張伯薰. "Investigation of Porous Ceramic Covered with Nano Particles on Anti-septic and Algae-removing." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/9d33rv.

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碩士<br>國立臺北科技大學<br>材料科學與工程研究所<br>96<br>Study of the porosity ceramics is basically made up of Al2O3 and SiO2. Nano -covered material contains nano TiO2, SiO2 and Al2O3 particles. By using a different test prescription to figure out the best spreading condition, nano material could be covered on the board of ceramics through directly attached and naturally dried to achieve the function of the antiseptic and algae-removing. Experimental result revealed that thickness of nano-covered material is approximately 100nm. After 1000 times washing and brushing of sponge, thickness of nano-covered materia
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Peake, Sandra Lois. "Combination anti-cytokine immunotherapy in an ovine model of gram-negative septic shock / by Sandra Peake." Thesis, 2000. http://hdl.handle.net/2440/21751.

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Bibliography: leaves 288-336.<br>336, vi leaves : ill. (chiefly col.) ; 30 cm.<br>This thesis examines the role of ant-cytokine monoclonal antibodies (mAb) as an adjunctive treatment in an animal model of septic shock. In particular, the role of combination immunotherapies directed against more than one cytokine is investigated.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 2001
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Chen, I.-Ju, and 陳怡如. "Therapeutic Effect of Acupoint Catgut Embedding in Obese Women and Anti-Inflammatory Effect in Lipopolysaccharides-Induced Septic Shock in Mice." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/ba4u58.

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博士<br>國立陽明大學<br>傳統醫藥研究所<br>106<br>Obesity has become a noticeable and worldwide public health problem recently. Recently, acupoint catgut embedding treatment (ACET), an extensive form of acupuncture, has become popular in weight reduction. Obesity has also been recognized recently as an inflammatory disease. It was demonstrated that mice injected with lipopolysaccharide (LPS) secreted from E. Coli subcutaneously for four consecutive weeks would cause a low degree of inflammation in these mice that lead to obesity. Previous study has reported a case of ACET resulted in local infection and tende
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Книги з теми "Anti-septic"

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Frost & Sullivan., ed. U.S. septicemia and septic shock markets: The search for therapy continues : new agents and their potential. Frost & Sullivan, 1994.

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Eichacker, Peter Q., and Jérôme Pugin. Evolving Concepts in Sepsis and Septic Shock. Springer London, Limited, 2012.

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Eichacker, Peter Q., and Jerome Pugin. Evolving Concepts in Sepsis and Septic Shock. Springer, 2012.

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(Editor), Peter Q. Eichacker, and Jérôme Pugin (Editor), eds. Evolving Concepts in Sepsis and Septic Shock (Perspectives on Critical Care Infectious Diseases). Springer, 2001.

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Gruninger, Romaine. Rheumatoid Arthritis Cookbook : Anti-Inflammatory Recipes to Fight Flares and Fatigue: Septic Arthritis. Independently Published, 2021.

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European septicaemia and septic shock therapy markets. Frost & Sullivan, 1993.

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Litell, John M., and Nathan I. Shapiro. Pathophysiology of septic shock. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0297.

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The pathophysiology of sepsis is the result of a dysregulated host response to infection. Interactions between conserved pathogenic signals and host recognition systems initiate a systemic reaction to local infection. Pro- and anti-inflammatory intermediates and associated coagulatory abnormalities lead to altered macrovascular, microvascular, and mitochondrial function. Uncorrected, these processes yield similar patterns of failure in multiple organ systems. Mortality increases with successive organ failures. Although commonly thought to be a manifestation of impaired renal circulation, septi
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), William Roberts (Surgeon. Mr. Warburton's Anatomy Bill, Thoughts on Its Mischievous Tendency; with Suggestions for an Entirely New One, Founded upon an ... Anti-Septic Process, Etc. HardPress, 2020.

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Maddux, Aline B., and Gordon R. Bernard. Immunomodulation strategies in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0312.

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Severe sepsis is a hyperimmune response to an infectious stimulus resulting in a surge of cytokines and mediators of inflammation. High circulating levels of pro-inflammatory cytokines lead to shock, multiple organ failure, and death in septic patients. It has been recognized that patients with sepsis progress into a state of immune paralysis characterized by immune cell apoptosis and high levels of anti-inflammatory cytokines… Anti-inflammatory cytokines suppress production of pro-inflammatory cytokines and inhibit monocytes from presenting antigens to other immune cells. Immune paralysis pro
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Gaston, J. S. Hill. Reactive arthritis and enteropathic arthropathy. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0115.

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Reactive arthritis (ReA), and enteropathic arthritis secondary to inflammatory bowel disease, are forms of spondyloarthritis, all of which share an association with HLA B27 and can involve both axial and peripheral joints. Genetic studies strongly implicate the cytokines IL-17 and IL-23 in their pathogenesis, and evidence for autoimmunity is lacking. ReA is triggered by particular bacteria, mainly affecting the gut and genitourinary tract, though infections are sometimes asymptomatic. Classically an acute oligo- or monoarthritis with enthesitis occurs, often with inflammatory back pain, though
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Частини книг з теми "Anti-septic"

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Gooch, Jan W. "Anti-Septic Wash." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_717.

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Eichacker, P. Q., and C. Natanson. "Rethinking the Anti-Inflammatory Approach to Septic Shock." In Yearbook of Intensive Care and Emergency Medicine. Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-80053-5_15.

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Monti, Gianpaola, Maurizio Bottiroli, Giacinto Pizzilli, et al. "Endotoxin Activity Level and Septic Shock: A Possible Role for Specific Anti-Endotoxin Therapy?" In Contributions to Nephrology. KARGER, 2010. http://dx.doi.org/10.1159/000315924.

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Waterstrat, R., R. W. Glaser, H. Tanzmann, C. H. Riese, and U. Marx. "Cultivation and Downstream Processing of a Human Monoclonal Anti-Alpha Haemolysin Antibody for the Treatment of Septic Patients." In Animal Cell Technology: Developments Towards the 21st Century. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0437-1_101.

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Li, Yongqing, and Hasan B. Alam. "Creating a Pro-survival and Anti-inflammatory Phenotype by Modulation of Acetylation in Models of Hemorrhagic and Septic Shock." In Advances in Experimental Medicine and Biology. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-5638-5_11.

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Nasa, Prashant, Rajesh Kumar, Deven Juneja, and Supradip Gosh. "The Case for Albumin as Volume Expander and beyond." In Rational Use of Intravenous Fluids in Critically Ill Patients. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42205-8_10.

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AbstractThis chapter discusses the importance of endogenous albumin, the most abundant plasma protein in the body. Albumin has diverse functions such as antioxidant, anti-inflammatory activities, intravascular buffering, drug metabolism, transport, distribution, and restoration of vascular endothelial integrity. It is also crucial for maintaining the endothelial glycocalyx layer in blood vessels. Critically ill patients may experience hypoalbuminemia, defined as serum albumin &lt;35 g/L, due to reduced synthesis, malnutrition, increased loss, or increased catabolism. Observational studies show
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Sevransky, Jonathan, and Charles Natanson. "Anti-Inflammatory Therapy in Sepsis." In Evolving Concepts in Sepsis and Septic Shock. Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-1581-4_9.

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Dhainaut, Jean-François, Nathalie Marin, and Alain Cariou. "Perspectives in Anti-Inflammatory Therapies in Sepsis." In Evolving Concepts in Sepsis and Septic Shock. Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-1581-4_10.

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Rogy, Michael A. "Gene therapy — an alternative approach for anti-cytokine therapies." In Cytokines in Severe Sepsis and Septic Shock. Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-8755-7_18.

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"Anti-septic wash." In Encyclopedic Dictionary of Polymers. Springer New York, 2006. http://dx.doi.org/10.1007/978-0-387-30160-0_706.

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Тези доповідей конференцій з теми "Anti-septic"

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Mu, S., Z. Song, and W. Wei. "Gut Microbiota Modulation and Anti-Inflammatory Properties of Xuanbai Chengqi Decoction in Septic Rats." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5267.

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Chanderraj, R., Y. He, M. Nuppnau, K. Winner, R. P. Dickson, and M. W. Sjoding. "In Septic Patients, Early Treatment With Anti-anaerobic Antibiotics Increases 90-day Mortality in an Instrumental Variable Analysis." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6382.

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Blamback, M., F. Hesselvik, B. Brodin, R. Maller, and R. Gaffney. "COAGUIATION, FIBRINLYSIS AND KALLIKREIN ACTIVATION IN SEVERE INFECTION AND SEPSIS : RELATION TO OUTCOME." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644695.

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Fatal multiple organ failure following severe infection may be related to early activation of protease cascade systems. The study aimed to relate changes in the below mentioned components to shock and outcome. Of 53 patients with severe infection, 30 did not develop shock (group I); 12 survived septic shock (groupII); and 11 died from organ failure after septic shock (groupIII). No patient had overt DIC. During the first 3 days after admission, blood was sampled daily for assay of: platelet count, fibrinogen, prothrombin complex, F XII, F VIIIiC, vWF:Ag, F VII, F V, anti thrombin, protein C, p
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Ziemen, M., M. Fierek, A. Francos, J. Si nn, and K. Breddin. "FIBRONECTIN, ANTITHROMBIN III, VON WILLEBRAND-FACTOR-ANTIGEN AND THROMBOCYTES DURING SEPTICEMIA, PNEUMONIA, SHOCK AND POLYTRAUMA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644246.

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In 56 patients with septicemia (N=10), septic shock (N=10), cardiogenic shock (N=7), bacterial pneumonia (N=6) and polytraumatized patients (N=23) fibronectin, von Wi11ebrand-factor-anti gen (vWF:AG), fibrinogen, antithrombin III (AT III) and platelet count were measured during the first week of illness. Like fibronectin vWF:AG is synthesized in the endothelial cells and is a mediator for platelet adhesion. Decrease of AT III and platelet count are sensitive indicators if activation of haemostasisIn all patients with septic shock on the first day of illness fibronectin was decreased (12.9ଗ.2mg
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Petrović, Miloš, Radojica Đoković, Vladimir Kurćubić, Snežana Bogosavljević-Bošković, Simeon Rakonjac, and Milun Petrović. "Intracellular and extracellular Hsp70 in cows: Similarities and differences in physiological and pathophysiology conditions." In Zbornik radova 26. medunarodni kongres Mediteranske federacije za zdravlje i produkciju preživara - FeMeSPRum. Poljoprivredni fakultet Novi Sad, 2024. http://dx.doi.org/10.5937/femesprumns24025p.

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Heat shock proteins (Hsp), also called chaperones, are proteins that are indispensable for the proper formation of the polypeptide chain; and have a role in its translocation within the cell. Hsp70 in cells helps to re-establish the native conformation of proteins that have denatured under the influence of various stressogens, by preventing their aggregation, which results in protecting the cell from apoptosis and having an anti-inflammatory effect. These proteins are classified on the basis of molecular mass, and the most significant is heat shock protein 70 (Hsp70) with a molecular mass of a
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Звіти організацій з теми "Anti-septic"

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Neodo, Anna, Fiona Augsburger, Jan Waskowski, Joerg C. Schefold, and Thibaud Spinetti. Monocytic HLA-DR expression and clinical outcomes in adult ICU patients with sepsis – a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0119.

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Анотація:
Review question / Objective: The scope of this review was defined using PICOTS framework where 1) population: adult critically ill patients with sepsis or septic shock; 2) index prognostic factor: cell surface protein expression of mHLA-DR in blood; 3) comparative factor: none; 4) outcomes to be predicted: mortality, secondary infections, length of stay, and organ dysfunction score (sequential organ failure assessment [SOFA], multiple organ dysfunction score [MODS], logistic organ dysfunction score [LODS]), composite outcomes where component endpoints consist of at least one of the outcomes st
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