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1

Akash, ingale Dr. Parag patil. "Aquasomes: A Novel Carrier for Drug Delivery." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 9–14. https://doi.org/10.5281/zenodo.14253031.

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Анотація:
This method is known worldwide for nanoparticular carriers referred to as aquasomes. Aquasomes are the type of nanoparticles and made up of three-layered self-assembled structures, consisting of a solid-phase nanocrystalline core covered with oligomeric film, biochemically active molecules that are typically absorbed with or without modification. Aquasomes are a nano-biopharmaceutical carrier device consisting of a particle center made up of a nanocrystalline calcium phosphate or a ceramic diamond surrounded by a polyhydroxy oligomeric film. Aquasomes are spherical in form containing 60–
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2

M, Megha, P., Sivakumar, R, Ranitha, R, and Punnya, E. P. "Aquasomes: A Promising Delivery Systems for Poorly Soluble Bioactives." Saudi Journal of Medical and Pharmaceutical Sciences 10, no. 08 (2024): 531–36. http://dx.doi.org/10.36348/sjmps.2024.v10i08.002.

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Aquasomes are considered an excellent and efficient carrier system for the transport of drugs or biochemically active long chain macromolecules such as proteins and peptides, various hormones, antigens, enzymes, and genes in the recently burgeoning field of nanobiotechnology research. These are three-layer self-collecting structures composed of an oligomeric film covering a strong stage nanocrystalline centre to which biochemically dynamic particles adhere to, independent of changes in the environment and which self-assembles through non-covalent or ionic connections. Aquasomes are circular pa
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3

Sirikonda, Ajay Kumar, B. Vijay Kumar, A. Soma Sekhar, M. Gopi, H. Seshu Babu, and G. Subba Rao. "ChemInform Abstract: Aquasomes: A Review." ChemInform 45, no. 14 (2014): no. http://dx.doi.org/10.1002/chin.201414261.

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4

S, Venkateswara Rao, Jagadeeswari N, and Padmalatha K. "Aquasomes: A Nanoparticulate Drug Carrier System." American Journal of PharmTech Research 8, no. 6 (2018): 28–37. http://dx.doi.org/10.46624/ajptr.2018.v8.i6.004.

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5

Banerjee, Sritoma, and Kalyan Kumar Sen. "Aquasomes: A novel nanoparticulate drug carrier." Journal of Drug Delivery Science and Technology 43 (February 2018): 446–52. http://dx.doi.org/10.1016/j.jddst.2017.11.011.

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6

Nanjwade, Basavaraj K., Gurudev M. Hiremath, F. V. Manvi, and Teerapon Srichana. "Formulation and Evaluation of Etoposide Loaded Aquasomes." Journal of Nanopharmaceutics and Drug Delivery 1, no. 1 (2013): 92–101. http://dx.doi.org/10.1166/jnd.2013.1016.

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7

Haranath, Chinthaginjala. "Aquasomes: A novel approach for the delivery of bioactive molecules." Journal of medical pharmaceutical and allied sciences 11, no. 5 (2022): 5325–30. http://dx.doi.org/10.55522/jmpas.v11i5.4110.

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Анотація:
In recent years, nanoscience has drug development and has taken a new slant, that have proven difficult with traditional dosage forms in drug delivery.Nanoparticles, liposomes, niosomes, quantum dots and Aquasomes are the examples of nanomaterials are just a few examples of nanobiotechnologically created carrier systems. The nano-particulate self-assembled carrier system is anew approachas well as ideal choice for the administration of drugs. Aquasomes proved to be important drug delivery system of ceramic nanoparticles.These are three-tiered framework composed of a core made of solid crystals
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8

Aman, Parashar*. "LITERATURE REVIEW ON AQUASOMES- A DRUG CARRIER SYSTEM." Indian Journal of Medical Research and Pharmaceutical Sciences 4, no. 11 (2017): 27–30. https://doi.org/10.5281/zenodo.1054693.

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Анотація:
Aquasomes are round particles made up of calcium phosphate or ceramic diamond coated with a polyhydroxyloligomeric film and perform as nanoparticulate carrier system but despite of being simple Nanoparticles these are three layered self-assembled structures, made up of a solid phase nanocrystalline core coated with oligomeric film on which biochemically active molecules are adsorbed with or without changes. The strong center core gives the structural stability, however the carbohydrate coating provides protection against dehydration and stabilizes the biochemically active molecules. After synt
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9

Gupta, Ajay Kumar, Diptee Gupta, and Vedant Gupta. "Aquasomes: A Self-Assembled Nano-Particulate Carrier System." International Journal of Current Research and Review 13, no. 04 (2021): 44–52. http://dx.doi.org/10.31782/ijcrr.2021.13427.

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10

Chaudhari, M. J., D. P. Pandya, P. P. Thakkar, A. M. Soni, and D. A. Modi. "ChemInform Abstract: Aquasomes: A Novel Drug Delivery System." ChemInform 44, no. 38 (2013): no. http://dx.doi.org/10.1002/chin.201338279.

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11

Pavani, Vengala, Shwetha Dintakurthi, Sana Aslam, Rekha Gollagudem, and Kumaraswamy Pabbapi. "ChemInform Abstract: Aquasomes: A Novel Drug Carrier System." ChemInform 44, no. 22 (2013): no. http://dx.doi.org/10.1002/chin.201322246.

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12

Gholap, Amol D., Santosh S. Borude, and Anand M. Mahajan. "ChemInform Abstract: Aquasomes: A Potential Drug Delivery Carrier." ChemInform 44, no. 11 (2013): no. http://dx.doi.org/10.1002/chin.201311265.

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13

Mesariya, Sunil, Kruti Joshi, Hitesh Jain, and U. M. Upadhyay. "ChemInform Abstract: Aquasomes - A Self-Assembled Nanotechnology System." ChemInform 43, no. 30 (2012): no. http://dx.doi.org/10.1002/chin.201230277.

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14

Kasture, Aditi. "Aquasomes: Harnessing Water-Soluble Nanoparticles for Biomedical Applications." International Journal of Pharma Professional's Research (IJPPR) 15, no. 2 (2024): 128–39. http://dx.doi.org/10.69580/ijppr.15.2.2024.128-139.

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15

Goyal, Amit K., Kapil Khatri, Neeraj Mishra, et al. "Aquasomes—A Nanoparticulate Approach for the Delivery of Antigen." Drug Development and Industrial Pharmacy 34, no. 12 (2008): 1297–305. http://dx.doi.org/10.1080/03639040802071661.

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16

Umashankar, Marakanam S., Rajesh K. Sachdeva, and Monica Gulati. "Aquasomes: a promising carrier for peptides and protein delivery." Nanomedicine: Nanotechnology, Biology and Medicine 6, no. 3 (2010): 419–26. http://dx.doi.org/10.1016/j.nano.2009.11.002.

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17

Rojas-Oviedo, Irma, Rodrigo A. Salazar-López, José Reyes-Gasga, and Carlos Tomás Quirino-Barreda. "Elaboration and structural analysis of aquasomes loaded with Indomethacin." European Journal of Pharmaceutical Sciences 32, no. 3 (2007): 223–30. http://dx.doi.org/10.1016/j.ejps.2007.07.008.

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18

Wani, S. U., and A. N. Yerawar. "ChemInform Abstract: Aquasomes: A Novel Nanocarrier for Drug Delivery." ChemInform 42, no. 46 (2011): no. http://dx.doi.org/10.1002/chin.201146279.

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19

Kutlehria, Abhilash, Peeyush Kaushik, Shaveta Sharma, and Arvind Kaur. "AQUASOMES AS A CARRIER SYSTEM FOR ORAL DELIVERY OF BROMELAIN." International Research Journal Of Pharmacy 9, no. 8 (2018): 123–29. http://dx.doi.org/10.7897/2230-8407.098177.

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20

Narang, Neha. "Aquasomes: Self-assembled systems for the delivery of bioactive molecules." Asian Journal of Pharmaceutics 6, no. 2 (2012): 95. http://dx.doi.org/10.4103/0973-8398.102931.

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21

Mr. Harshal Anil Mane, Mr Harshal Anil Mane, Miss Akshata Vishwanth Shinde, Mr Tejmal Premsing Rathod, et al. "Aquasomes: A Novel Nanoparticulate Drug Delivery System for Psoriasis Treatment." International Journal of Pharmaceutical Research and Applications 10, no. 3 (2025): 1922–28. https://doi.org/10.35629/4494-100319221928.

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Анотація:
New nanoparticulate carriers called aquasomes are applied topically to administer drugs, especially in dermatology. These carriers consist of a solid core, often made of calcium phosphate or ceramic, covered by a polyhydroxy oligomer layer. This unique shape protects the bioactivity of fragile molecules like proteins, enzymes, and genetic material. Aquasomes are particularly helpful for enhancing the regulated release, stability, and bioavailability of medicinal substances while lowering systemic absorption and undesirable side effects. Skin conditions are among the most prevalent health issue
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22

Umashankar, Marakanam S., Rajesh K. Sachdeva, and Monica Gulati. "ChemInform Abstract: Aquasomes: A Promising Carrier for Peptides and Protein Delivery." ChemInform 41, no. 51 (2010): no. http://dx.doi.org/10.1002/chin.201051269.

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23

Yadav, Akshay R., and Shrinivas K. Mohite. "Aquasomes as a self assembling nanobiopharmaceutical carrier system for bio-active molecules." RESEARCH JOURNAL OF TOPICAL AND COSMETIC SCIENCES 11, no. 2 (2020): 89–94. http://dx.doi.org/10.5958/2321-5844.2020.00016.3.

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24

Damera, Deepthi Priyanka, Sravani Kaja, Leela Sai Lokesh Janardhanam, Sk Alim, Venkata Vamsi Krishna Venuganti, and Amit Nag. "Synthesis, Detailed Characterization, and Dual Drug Delivery Application of BSA Loaded Aquasomes." ACS Applied Bio Materials 2, no. 10 (2019): 4471–84. http://dx.doi.org/10.1021/acsabm.9b00635.

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25

Kossovsky, N., A. Gelman, S. Rajguru, et al. "Control of molecular polymorphisms by a structured carbohydrate / ceramic delivery vehicle — aquasomes." Journal of Controlled Release 39, no. 2-3 (1996): 383–88. http://dx.doi.org/10.1016/0168-3659(95)00169-7.

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26

Kulkarni, Samruddhi, Bala Prabhakar, and Pravin Shende. "Nanodiamond-based berberine aquasomes for enhancing penetration across epidermis to treat psoriasis." International Journal of Pharmaceutics 656 (May 2024): 124051. http://dx.doi.org/10.1016/j.ijpharm.2024.124051.

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27

Patel, J. K., K. N. Patel, H. K. Patel, B. A. Patel, and P. A. Patel. "Aquasomes: A Self Assembling Nanobiopharmaceutical Carrier System for Bio-Active Molecules: A Review." International Journal for Pharmaceutical Research Scholars 1, no. 1 (2012): 11–21. http://dx.doi.org/10.31638/ijprs.v1.i1.00012.

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28

Rathore, Priyanka, Shipra Duggal, and Gaurav Swami. "ChemInform Abstract: Aquasomes: A Promising Nanobiopharmaceutical Drug Delivery System for Proteins and Peptides." ChemInform 44, no. 17 (2013): no. http://dx.doi.org/10.1002/chin.201317269.

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29

Hussein, Lamiaa M., Aya M. Dawaba, and Shereen A. Eladawy. "Formulation and Evaluation of Thermosensitive In situ Nasal Gel of Mirtazapine Loaded Aquasomes." Azhar International Journal of Pharmaceutical and Medical Sciences 4, no. 2 (2024): 43–57. http://dx.doi.org/10.21608/aijpms.2024.228175.1230.

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30

Ahmad, Usama, Zeeshan Ahmad, Ahmed Khan, Juber Akhtar, Satya Singh, and Farhan Ahmad. "Strategies in Development and Delivery of Nanotechnology Based Cosmetic Products." Drug Research 68, no. 10 (2018): 545–52. http://dx.doi.org/10.1055/a-0582-9372.

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Анотація:
AbstractThe science of formulation involving cosmetic ingredients has always been a challenge since the release of active components greatly depends upon the carrier system involved and the selectivity of skin barrier. The principle obstacle of the skin resides in the epidermis and it’s hard for many active components to cross it. The formulation related factors like size of particles, viscosity and lipophilicity of the components also play an important role in permeation of the dermal composition. Though widely used; conventional creams and gels still struggle in terms of success. This work f
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31

V. Viswanath and P. Tulasi. "Formulation, optimization and characterization of Betaxolol hydrochloride proniosomes using 3-2 factorial design." International Journal of Research in Pharmaceutical Sciences and Technology 1, no. 3 (2020): 89–97. http://dx.doi.org/10.33974/ijrpst.v1i3.161.

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The revolution in nanotechnology has lead to the development of various dosage forms such as vesicular drug delivery and in particular liposomes, niosomes, proniosomes, aquasomes, bilosomes etc. The disad-vantages exhibited by the liposomes, niosomes can be overcome through introduction of proniosomes which are compact liquid crystalline structures and convert to niosomes upon hydration. The investigation is focused on development and optimization of Betaxolol proniosomes using three square factorial design technique with the aid of design expert 11.0 ® trial version. The optimization techniqu
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32

Khopade, A. J., Surekha Khopade, and N. K. Jain. "Development of hemoglobin aquasomes from spherical hydroxyapatite cores precipitated in the presence of half-generation poly(amidoamine) dendrimer." International Journal of Pharmaceutics 241, no. 1 (2002): 145–54. http://dx.doi.org/10.1016/s0378-5173(02)00235-1.

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33

Jain, Shikha, Vikas Jain, and S. C. Mahajan. "Lipid Based Vesicular Drug Delivery Systems." Advances in Pharmaceutics 2014 (September 2, 2014): 1–12. http://dx.doi.org/10.1155/2014/574673.

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Vesicular drug delivery system can be defined as highly ordered assemblies consisting of one or more concentric bilayers formed as a result of self-assembling of amphiphilic building blocks in presence of water. Vesicular drug delivery systems are particularly important for targeted delivery of drugs because of their ability to localize the activity of drug at the site or organ of action thereby lowering its concentration at the other sites in body. Vesicular drug delivery system sustains drug action at a predetermined rate, relatively constant (zero order kinetics), efficient drug level in th
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34

Kaur, Kamaljeet, Preeti Kush, Ravi Shankar Pandey, Jitender Madan, Upendra Kumar Jain та Om Prakash Katare. "Stealth lipid coated aquasomes bearing recombinant human interferon-α-2b offered prolonged release and enhanced cytotoxicity in ovarian cancer cells". Biomedicine & Pharmacotherapy 69 (лютий 2015): 267–76. http://dx.doi.org/10.1016/j.biopha.2014.12.007.

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35

Tushar Rukari, Prashant Pingale, and Chandrashekhar Upasani. "Vesicular drug delivery systems for the fungal infections’ treatment through topical application-a systemic review." Journal of Current Science and Technology 13, no. 2 (2023): 500–516. http://dx.doi.org/10.59796/jcst.v13n2.2023.1856.

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Анотація:
In this systemic review, we tried to explore and summarize the Vesicular Drug Delivery Systems (VDDSs) which can exclusively used for topical applications in the treatment of fungal infections. The specific algorithm is developed for this systemic review, exclusion criteria for the review were set and results were excluded which were meets the exclusion criteria. To build a review, Google Scholar® and PubMed® are two databases that are targeted so that we can collect the number of freely available full-text articles and can minimize the risk of bias (unavailability of full-text articles, for t
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36

Pooja Mallya, Gowda D V, Mahendran B, Bhavya M V, and Vikas Jain. "Recent developments in nano micelles as drug delivery system." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 176–84. http://dx.doi.org/10.26452/ijrps.v11i1.1804.

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Targeting of the drug directly to the cells, tissues, or organs with no impact on healthy cells is a challenge. In the current era, it's been made possible by therapeutic interventions. The novel drug delivery systems such as nano particulates, liposomes, aquasomes, phytosomes, dendrimers, nano sponges, nano micelles are developed. Nano micelles are developed for efficient targeting and are currently in trend as therapeutic carriers of water-insoluble drugs. Micelles are self-assembling Nano-sized colloidal particles with a hydrophobic core and hydrophilic shell. Among the micelle-forming comp
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37

Rajak, Prakash, Rofiqul Islam, Arka Karmakar, and Biman Bhuyan. "Aquasomal drug delivery system: A special emphasis on the formulation techniques and applications." Ars Pharmaceutica (Internet) 64, no. 4 (2023): 359–75. http://dx.doi.org/10.30827/ars.v64i4.28264.

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Анотація:
Introduction: Aquasome is a self-assembled nanoparticulate carrier system with three layers. The system is made up of a polyhydroxy oligomer-coated inner nanocrystalline solid core. Adsorbed on the coated layer are drug molecules or biochemically active compounds. Self-assembly in this sense refers to the independent formation of molecules into organised, long-lasting, and non-covalently bonded patterns.This paper gives an overview of aquasome formation, covering structural properties, formulation methodologies, and the benefits and drawbacks of this novel drug delivery technology. The article
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38

EZEGBE, CHEKWUBE, Ogechukwu Umeh, and Sabinus Ofoefule. "Drug Carriers." Journal of Current Biomedical Research 2, no. 1 (2022): 77–105. http://dx.doi.org/10.54117/jcbr.v2i1.3.

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Анотація:
In recent years, there has been an exponential interest in the development of novel drug delivery systems using drug carriers. Drug carriers offer significant advantages over the conventional drug delivery systems in terms of high stability, high specificity, high drug loading capacity, controlled release of drug and ability to deliver both hydrophilic and hydrophobic drugs. As a result of their unique behaviors, drug carriers have a wide range of biomedical and industrial applications. Nanospheres are associated with a lot of benefits such as ease of administration to target sites, reduction
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39

Brikmans, Anastasia, Olga Nesterova, and Maria Bovsun. "The main characteristics of the aquasoils of the Ussuri Bay of the Sea of Japan." E3S Web of Conferences 498 (2024): 03015. http://dx.doi.org/10.1051/e3sconf/202449803015.

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The manuscript presents the main characteristics of aquasoils (granulometric composition, organic carbon, acid-base properties, total nitrogen) of the shelf zone of the Ussuri Bay of the Sea of Japan. A clear relationship between the content of organic carbon and fractions of granulometric composition in the studied samples was revealed. The excess of the maximum permissible concentrations values for lead was detected for only one point. The rest of the aquasoils are not contaminated with lead.
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40

Patil, Aishwarya Chagan, Shital Sanjay Shewale, Yogita Tukaram Rayate, M. Manojkumar Nitalikar, and Shreenivas K. Mohite. "Review on Aquasome novel drug delivery system." Research Journal of Topical and Cosmetic Sciences 9, no. 1 (2018): 19. http://dx.doi.org/10.5958/2321-5844.2018.00005.5.

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41

Jagdale, Sachin, and Simran Karekar. "Bird's eye view on aquasome: Formulation and application." Journal of Drug Delivery Science and Technology 58 (August 2020): 101776. http://dx.doi.org/10.1016/j.jddst.2020.101776.

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42

Huang, Haiou, Rodrigue Spinette, and Charles R. O’Melia. "Direct-flow microfiltration of aquasols." Journal of Membrane Science 314, no. 1-2 (2008): 90–100. http://dx.doi.org/10.1016/j.memsci.2008.01.040.

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43

Sahu, Varsha, Sunit Kumar Sahoo, and Amaresh Chandra Sahoo. "Aquasome: As Drug Delivery Carrier in the Pharmaceutical Field." Indian Journal of Pharmaceutical Education and Research 58, no. 3s (2024): s757—s767. http://dx.doi.org/10.5530/ijper.58.3s.77.

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44

Bredereck, Karl, Franz Effenberger, and Michael Tretter. "Preparation and characterization of silica aquasols." Journal of Colloid and Interface Science 360, no. 2 (2011): 408–14. http://dx.doi.org/10.1016/j.jcis.2011.04.062.

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45

Sharma, Sanjay, Anshita Gupta, Harish Niranjan, and Manoj Goyal. "ChemInform Abstract: Aquasome: A Novel Drug Delivery Approach Using Nanocrystaline Biomaterial." ChemInform 44, no. 22 (2013): no. http://dx.doi.org/10.1002/chin.201322247.

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46

Hahn, Melinda W., Dean Abadzic, and Charles R. O'Melia. "Aquasols: On the Role of Secondary Minima†." Environmental Science & Technology 38, no. 22 (2004): 5915–24. http://dx.doi.org/10.1021/es049746d.

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47

Nesterova, Olga, Anastasia Kvashnina, Anastasia Brikmans, Maria Bovsun, and Viktoriia Semal. "The aquasoils humus of the Ussuri Bay in the Sea of Japan." E3S Web of Conferences 592 (2024): 06002. http://dx.doi.org/10.1051/e3sconf/202459206002.

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Анотація:
The study investigates the main characteristics humus of aquasoils (organic carbon, type of humus, content of humic and fulvic acids, E4/E6, acid-base properties, total nitrogen) in the Ussuri Bay shelf zone of the Sea of Japan. A strong (close) relationship is observed in organic carbon with carbon of humic acids and carbon of non-hydrolysable residue. The average content of organic carbon throughout the entire water area of the Ussuri Bay was 0.91%. Most of the water area of the Ussuri Bay is represented by a humate type of humus.
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48

Bardi, Ugo. "Fresh water production by means of solar concentration: the AQUASOLIS project." Desalination 220, no. 1-3 (2008): 588–91. http://dx.doi.org/10.1016/j.desal.2007.04.059.

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Kokhanenko, P., K. Brown, and M. Jermy. "Silica aquasols of incipient instability: Synthesis, growth kinetics and long term stability." Colloids and Surfaces A: Physicochemical and Engineering Aspects 493 (March 2016): 18–31. http://dx.doi.org/10.1016/j.colsurfa.2015.10.026.

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Shubham, Mane Vidya Kale. "A Review on Novel Drug Delivery System." International Journal of Pharmaceutical Sciences 2, no. 6 (2024): 1099–111. https://doi.org/10.5281/zenodo.12491082.

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Анотація:
Quest for Novel Drug Delivery System (NDDS) has started since long back, but it has got momentum since last few decades. NDDS has several advantages over the conventional dosage form which includes better therapeutic outcome. NDDS is also preferred in the new patent regimen as this is one of the ways to introduce new products in the regulated market. Several types of NDDS have been developed during last few decades which are- Microparticles, Nanoparticles, Osmotically Modulated Drug Delivery Systems, Transdermal Therapeutic Systems (TTS), Aquasome, Dendrimers, Multiple Emulsions, Microemulsion
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