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Дисертації з теми "Blood-vessels"

Автор: Grafiati

Опубліковано: 4 червня 2021

Оновлено: 25 липня 2025

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1

Carter, A. J. "Thromboxane synthesis in human blood platelets and blood vessels." Thesis, University of Nottingham, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355288.

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2

Au, Pakwai. "Engineering functional blood vessels in vivo." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43867.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2008.<br>Includes bibliographical references.<br>At the present time, there are many hurdles to overcome in order to create a long-lasting and engineered tissue for tissue transplant in patients. The challenges include the isolation and expansion of appropriate cells, the arrangement of assorted cells into correct spatial organization, and the development of proper growth conditions. Furthermore, the creation of a three dimensional engineered tissue is limited by the fact that tissue assemblies greater than 100-200 microm

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3

HYNES, MICHAEL RAY. "ENDOTHELIUM-DEPENDENT RELAXATION OF BLOOD VESSELS." Diss., The University of Arizona, 1987. http://hdl.handle.net/10150/184134.

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Dilation of blood vessels in response to a large number of agents has been shown to be dependent on an intact vascular endothelium. The present studies examine some aspects of endothelium-dependent vasodilation in blood vessels of the rabbit and rat. Using the rabbit ear artery and the subtype-selective muscarinic antagonist pirenzepine, muscarinic receptors of the endothelium and smooth muscle cells were shown to be of the low affinity M₂ subtype. Inhibition of [³H](-)quinuclidinyl benzilate was used to determine affinity for the smooth muscle receptors while antagonism of methacholine induce

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4

Mancini, Maria L. "Novel Roles for Endoglin in Vascular Development and Maintenance of Vascular Integrity." Fogler Library, University of Maine, 2007. http://www.library.umaine.edu/theses/pdf/ManciniML2007.pdf.

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5

Arief, Melissa Suen. "Human Tissue Engineered Small Diameter Blood Vessels." Yale University, 2010. http://ymtdl.med.yale.edu/theses/available/etd-03152010-144428/.

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The engineering of human vascular grafts is an intense area of study since there is crucial need for alternatives to native vein or artery for vascular surgery. This current study sought to prove that a tissue engineered blood vessel (TEBV) 1mm in diameter could be developed from human smooth muscle cells and that endothelial progenitor cells (EPCs) could be cultured and used to endothelialize these grafts. This project had four specific aims: the isolation and characterization of EPCs, the seeding of a novel scaffold with EPCs and exposure to physiologic shear stress in vitro, the development

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6

Dritsoula, A. "Regulation of NKX2-5 in blood vessels." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1551692/.

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NKX2-5 is a transcription factor required for the formation of the heart and vessels during development. Postnatal expression is significantly downregulated, and then re-activated in diseased conditions characterised by vascular remodelling. However, the mechanisms regulating NKX2-5 activation in diseased vessels remain unknown. The aim of this thesis is to identify these mechanisms and provide information on how the gene contributes to cardiovascular pathologies, such as sclerodermaassociated pulmonary hypertension. A case-control genetic association study was performed in two independent coh

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7

Kaur, Amaratpal. "Optical remote sensing of hypertensive blood vessels." Thesis, Loughborough University, 1997. https://dspace.lboro.ac.uk/2134/32228.

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The aim of this research is to investigate the effects of hypertension on small artery structure by extending the instrumentation which is available for optical analysis of vessels in-vitro. Conventionally, arterial vessels are pressurised in a perfusion myograph and are analysed by video microscopy. A key objective of this research is to enable the examination of vessels by absorption spectroscopy.

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8

Omatuku, Emmanuel Ngongo. "Modelling of Residual Stresses of Blood Vessels." Thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/21604.

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The diagnosis of vascular diseases can be achieved with a suitably determined circumferential stress at arterial walls. The stress distribution over arterial walls in blood vessels is affected by residual stresses and stresses due to blood pressure. However, residual stresses are still not reliably determined. For this reason, a suitable incorporation of these stresses is required in order to establish the wall stress as a reliable diagnostic indicator. Thus this study aims to model residual stresses by incorporating them into the wall stress distribution, and to investigate the effect that p

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9

Williams, Chrysanthi. "Perfusion bioreactor for tissue-engineered blood vessels." Diss., Available online, Georgia Institute of Technology, 2004:, 2003. http://etd.gatech.edu/theses/available/etd-06072004-131410/unrestricted/williams%5Fchrysantyhi%5F200405%5Fphd.pdf.

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10

Kuzborska, Zyta. "Research of blood flow and stresses in the pathological blood vessels." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120131_135725-24904.

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Physical load, age and gender influence to blood pressure and maximal stresses in the pathological blood vessel palaces was studies in this work. The main research subject – pathological blood vessel and its blood flow processes that depend on physical load, pathology degree and type, age, gender and blood vessels stress characteristics. The main aim of this work – to examine blood flow characteristics, local blood pressure, stress distribution in the pathological blood vessels dependent physical load assessing blood vessels mechanical properties variations due to age, gender, blood vessel pat

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11

Myers, Daniel. "The Role of Osteopontin in Vascular Remodeling." Fogler Library, University of Maine, 2004. http://www.library.umaine.edu/theses/pdf/MyersDL2004.pdf.

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12

Scott, Matthew. "The modeling of blood rheology in small vessels." Thesis, University of Waterloo, 2005. http://hdl.handle.net/10012/1149.

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Blood is a dense suspension of flexible red blood cells. In response to a background flow, these cells distribute themselves non-uniformly throughout the vessel. As a result, material properties that are well defined in homogeneous fluids, such as viscosity, are no longer so, and depend upon the flow geometry along with the particle properties. Using a simple model that accounts for the steady-state particle distribution in vessel flow, we derive an expression for the effective viscosity of blood and the suspension flow velocity field in a pressure-driven tube flow. <br /><br /> We d

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13

Pate, Michael Alastair. "Characterisation of endothelin receptors in human blood vessels." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392486.

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14

Fierro, Murga Leobardo. "Analysis of countercurrent exchange between paired blood vessels." Diss., The University of Arizona, 1993. http://hdl.handle.net/10150/186130.

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Throughout much of the blood circulatory system, supply vessels (arteries and arterioles) are situated adjacent to corresponding draining vessels (veins and venules), which flow in the opposite direction. In this dissertation, mathematical models are developed to describe diffusive exchange of heat, oxygen and inert gases between such paired countercurrent blood vessels and surrounding tissue. In preliminary analyses, exchange between a single vessel and surrounding tissue is considered. The concept of equilibration length is developed. Then a well-known solution for two-dimensional diffusion

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15

Kristo, Aleksandra S. "The Effect of Wild Blueberries on Endothelium-Dependent Vasodilation in Spontaneously Hypertensive Rats." Fogler Library, University of Maine, 2008. http://www.library.umaine.edu/theses/pdf/KristoAS2008.pdf.

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16

Yuan, Yuan. "Multi-scale vessel enhancement using local line integrals and variational optimization /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?CSED%202008%20YUAN.

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17

Robertson, Zoe. "An in vitro study of the effect of silicon and magnesium ions on bone repair and angiogenesis." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25934.

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18

Clark, Kateryna. "Wild Blueberries Affect Endothelium-dependant Vasodilation in Sprague-Dawley and Spontaneously Hypertensive Rats." Fogler Library, University of Maine, 2007. http://www.library.umaine.edu/theses/pdf/ClarkK2007.pdf.

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19

Zoellner, Hans. "The vascular response in chronic periodontitis." Thesis, The University of Sydney, 1990. http://hdl.handle.net/2123/4468.

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Анотація:

This thesis describes work done at the Institute of Dental Research in Sydney between February of 1986 and January 1990. The broad subject of the work is the role of vascular endothelial cells (ECs) in chronic inflammation. Periodontitis has been used as an example of chronic inflammatory disease, and provides the focus for this study of endothelial biology. In Chapter 1, aspects of the endothelial literature which provide relevant background information for work described in later chapters are reviewed. In Chapter 2, literature relating to aetiology and pathogenesis of chronic inflammatory pe

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20

Zoellner, Hans. "The vascular response in chronic periodontitis." University of Sydney, 1990. http://hdl.handle.net/2123/4468.

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Анотація:

Doctor of Philosophy<br>This thesis describes work done at the Institute of Dental Research in Sydney between February of 1986 and January 1990. The broad subject of the work is the role of vascular endothelial cells (ECs) in chronic inflammation. Periodontitis has been used as an example of chronic inflammatory disease, and provides the focus for this study of endothelial biology. In Chapter 1, aspects of the endothelial literature which provide relevant background information for work described in later chapters are reviewed. In Chapter 2, literature relating to aetiology and pathogenesis of

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21

Huijbers, Elisabeth J. M. "Development of a Cancer Vaccine Targeting Tumor Blood Vessels." Doctoral thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-170887.

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A treatment strategy for cancer is the suppression of tumor growth by directing an immune response to the tumor vessels, which will destroy the tissue. In this thesis we describe the development of a vaccine that targets antigens expressed around angiogenic vasculature in most solid tumors. These antigens are alternative spliced extra domains of glycoproteins present in the extracellular matrix; e.g. the extra domain-B (ED-B) and extra domain-A (ED-A) of fibronectin and the C-domain of tenascin-C (TNCC). We show that it is possible to break self-tolerance and induce a strong antibody response

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22

Razavi, Habib M. "Conduit versus resistance blood vessels, adrenoceptors and nitric oxide." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0011/MQ40846.pdf.

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23

Lohsiriwat, Varut. "characterisation of receptors on blood vessels in haemorrhoid tissue." Thesis, University of Nottingham, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.537691.

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24

Caldwell, Mark Alexander. "Modeling blood vessels and oxygen diffusion into brain tissue." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1565276066111476.

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25

Norotte, Cyrille Forgács G. "From developmental biology to tissue-engineering printing blood vessels /." Diss., Columbia, Mo. : University of Missouri--Columbia, 2009. http://hdl.handle.net/10355/6188.

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Анотація:

Title from PDF of title page (University of Missouri--Columbia, viewed on Feb 15, 2010). The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. Dissertation advisor: Dr. Gabor Forgacs. Vita. Includes bibliographical references.

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26

Zdanowski, Zbigniew. "Synthetic vascular graft infection an experimental study with special reference to host mechanisms affecting bacterial graft colonization /." Lund : Dept. of Surgery, Lund University, 1993. http://catalog.hathitrust.org/api/volumes/oclc/39798633.html.

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27

Keung, Wen-yee Wendy, and 姜韻兒. "Mechanisms of acute actions of 17B-estradiol in the vascular system." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B29697487.

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28

Chan, Yap-hang, and 陳熠恆. "Role of phytoestrogen in vascular function and dysfunction." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B40733725.

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29

黃鉦沅 and Ching-yuen Wong. "Impact of diet on vascular function in patients with type II diabetes mellitus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42904936.

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30

Zhao, Yingzi, and 趙瑩子. "Acute and chronic impact of pressure on vascular responsiveness." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/207185.

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Анотація:

Hypertension leads to vascular complications including endothelial dysfunction, heart failure and stroke. The purpose of the present studies was to investigate the chronic and acute impact of high pressure on vascular responsiveness. In Study I, isometric tension measurements demonstrated that contractions to phenylephrine, in the presence of indomethacin (inhibitor of cyclooxygenase), were smaller in aortae of spontaneously hypertensive rats (SHR) with, than in those without, endothelium, while they were comparable in such preparations of normotensive Wistar-Kyoto rat (WKY); the difference

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31

Burbridge, Michael Frank. "The rat aortic ring model of angiogenesis in vitro as an assay for angiogenic modulators, the role of the matrix metalloproteinases in vessel formation." Thesis, University of Liverpool, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367795.

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32

Chan, Yap-hang. "Role of phytoestrogen in vascular function and dysfunction." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B40733725.

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33

Johnson, Lynelle. "Effects of exercise training on pulmonary vasomotor responses in the pig /." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9974642.

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34

Wong, Ching-yuen. "Impact of diet on vascular function in patients with type II diabetes mellitus." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42904936.

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35

Schindelhauer, Nancy Lynn. "Trophic interactions between rat thigh blood vessels and their innervation." Thesis, University of British Columbia, 1986. http://hdl.handle.net/2429/26069.

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Much less work has been done on the denervation of smooth muscle compared with the extensive studies carried out on skeletal muscle. It was thought that denervation of smooth muscle produced few alterations in its morphology or physiology, especially since many blood vessels have virtually no innervation, and therefore, they can survive without it. Simple severing or excising a section of nerve trunk is sufficient to denervate skeletal muscle, but this does not apply to smooth muscle. Therefore, denervation methods for smooth muscle have included those with widespread effects such as chemical

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36

Elliot, Jonathan. "Semicarbazide-sensitive amine oxidase of blood vessels : a functional study." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316733.

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37

Bradley, Jane Louise. "Quantitative aspects of blood vessels and perineurium in diabetic neuropathy." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307586.

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38

Lee, Carol Hsiu-Yueh. "Electrospun Polycaprolactone Scaffolds for Small-Diameter Tissue Engineered Blood Vessels." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1376924954.

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39

Strobel, Hannah A. "Engineered blood vessels with spatially distinct regions for disease modeling." Digital WPI, 2018. https://digitalcommons.wpi.edu/etd-dissertations/541.

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Анотація:

Tissue engineered blood vessels (TEBVs) have great potential as tools for disease modeling and drug screening. However, existing methods for fabricating TEBVs create homogenous tissue tubes, which may not be conducive to modeling focal vascular diseases such as intimal hyperplasia or aneurysm. In contrast, our lab has a unique modular system for fabricating TEBVs. Smooth muscle cells (SMCs) are seeded into an annular agarose mold, where they aggregate into vascular tissue rings, which can be stacked and fused into small diameter TEBVs. Our goal is to create a platform technology that may be us

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40

Law, Wai Kong. "Segmentation of vessels using weighted local variances and an active contour model /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?COMP%202006%20LAW.

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41

Huang, Min, and 黃民. "Modulation of low density lipoprotein oxidation and its effects on vascular function." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B3123706X.

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42

Cheung, Ka-hei, and 張嘉熹. "Adaptive clutter filter design for micro-ultrasound color flow imagingof small blood vessels." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45517873.

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43

Nicholls, Juliet A. "Ca'2'+ mobilisation in cultured human vascular smooth muscle cells." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295537.

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44

Hanzlik, Josa A. "Effects of complex vessel geometrics on neutrophil margination and adhesion in post-capillary vessels /." Online version of thesis, 2008. http://hdl.handle.net/1850/9990.

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45

Huang, Min. "Modulation of low density lipoprotein oxidation and its effects on vascular function /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19905038.

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46

Bosch, Rué Èlia. "Strategies to induce vascularization: angiogenesis stimulation and tissue engineering blood vessels." Doctoral thesis, Universitat Internacional de Catalunya, 2021. http://hdl.handle.net/10803/670474.

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Angiogenesis, which results in a capillary network formation, is one of the crucial events that take place when there is tissue damage, being critical for successful tissue regeneration. It does not only allow the arrival of oxygen, nutrients and waste removal, but it also allows the arrival of progenitor cells necessary to induce tissue restoration. However, when there is an excessive damage, tissues are unable to regenerate by themselves. During the last decades, tissue engineering emerged as an alternative to improve tissue regeneration, with the combination of biomaterials (which serves as

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47

Mani, Mohammad H. "Ultrasonic instrument for accurate measurements of spatial parameters in blood vessels." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/33355/.

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The present research is aimed at the development of an ultrasonic medical instrument capable of measuring the intima-media thicknesses (IMT) of artery walls that are considered by medical practitioners as good indicators of the risk of atherosclerosis. This overcomes two notable limitations of the instruments available at present – insufficient axial resolution and lack of synchronisation to the heart cycle that make the measurements difficult to use, e.g., for annual screening of patients and like-for-like comparisons. These limitations were addressed by using a combination of on-the-fly aver

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48

Bai, Ni. "Impact of diesel exhaust inhalation on the heart and blood vessels." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/35864.

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Numerous epidemiological studies have shown that exposure to ambient particulate matter (PM) is implicated in increased cardiovascular morbidity and mortality; however, the biological mechanisms are not fully understood. Diesel exhaust (DE) is the single biggest contributor to the urban ambient PM, and accounts for up to 90% of the total mass of fine particulate mass in ambient air of many major cities, such as London. In this dissertation, I evaluated the effects of DE inhalation at an environmentally relevant level in a mouse model of atherosclerosis, the apolipoprotein E deficient (apoE kn

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49

Keen, John A. "Investigation of the structure and function of equine laminar blood vessels." Thesis, Glasgow Caledonian University, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.517934.

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50

Stone, Oliver Andrew. "On the origin of blood vessels : mechanisms of post-natal neovascularisation." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520634.

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