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Готові списки джерел за темами / Bradycardia APGAR / Статті в журналах

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Статті в журналах з теми "Bradycardia APGAR"

Автор: Grafiati

Опубліковано: 7 червня 2025

Оновлено: 2 серпня 2025

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1

Laraib Malik, Umbreen idrees, Alia Halim, Rakhshanda Aslam, RIZWANA NASREEN,, and Iqra Kanwal Malik. "Neonatal Outcomes in Intrapartum Pathological CTG in Low-risk Pregnancies." Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University 20, no. 3 (2024): 393–98. http://dx.doi.org/10.48036/apims.v20i3.1183.

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Objective: The study aimed to investigate the neonatal outcomes of intrapartum pathological CTG patterns in low-risk women during labor. Methodology: This retrospective cohort study included 120 low-risk pregnant women who experienced pathological CTG patterns during labor. This study was conducted over a period of 12 months, from May 2023 to April 2024, in PAF hospital, Islamabad. Low-risk women were defined as those without pre-existing medical conditions or obstetric complications. Pathological CTG patterns were identified and categorized based NICE guideline [NG229]. Data on neonatal outco

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2

Berisha, Gazmend, Line Norman Kvenshagen, Anne Marthe Boldingh, et al. "Video-Recorded Airway Suctioning of Clear and Meconium-Stained Amniotic Fluid and Associated Short-Term Outcomes in Moderately and Severely Depressed Preterm and Term Infants." Children 11, no. 1 (2023): 16. http://dx.doi.org/10.3390/children11010016.

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Background: The aim of this study was to investigate delivery room airway suctioning and associated short-term outcomes in depressed infants. Methods: This is a single-centre prospective observational study of transcribed video recordings of preterm (gestational age, GA < 37 weeks) and term (GA ≥ 37 weeks) infants with a 5 min Apgar score ≤ 7. We analysed the association between airway suctioning, breathing, bradycardia and prolonged resuscitation (≥10 min). For comparison, non-suctioned infants with a 5 min Apgar score ≤ 7 were included. Results: Two hundred suction episodes were performed

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3

Kazuo, Maeda*. "The hypoxia index covers roles of all decelerations and will reduce cerebral palsy." Journal of Gynecological Research and Obstetrics 4, no. 1 (2018): 005. https://doi.org/10.17352/jgro.000048.

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It was strange that fetal outcome was vigorous in 3 late decelerations, but ominous when it repeated. It was thought that FHR decelerations expresses hypoxia, because the heart rate was fully parallel to rabbit PaO2, if it is below 50mmHg, and human fetal PaO2 is 50mmHg or less. Thus, a hypoxia index (HI), that is hypoxic nature, was sum of deceleration duration (min) divided by the lowest nadir FHR (bpm), and multiplied by 100. Its calculation is easy by computer, though possible by manual calculation. HI has regression equation with Apgar score, and Apgar score was high in 2 to 3 late decele

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4

Sood, Devika, Prabhjeet Singh, Gegal Pruthi, et al. "Comparative Efficacy of Intermittent Bolus Doses of Phenylephrine and Norepinephrine in Preventing Maternal Bradycardia during Cesarean Section under Spinal Anesthesia: A Randomized Controlled Trial." Journal of Obstetric Anaesthesia and Critical Care 14, no. 2 (2024): 146–52. http://dx.doi.org/10.4103/joacc.joacc_81_23.

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Background and Aims: Maternal hypotension is a common concern during cesarean sections (CS) with spinal anesthesia and can have adverse consequences for both the mother and fetus. This study aimed to investigate the prophylactic effectiveness of intermittent boluses of phenylephrine and norepinephrine in preventing maternal bradycardia during maintenance of systolic blood pressure (SBP) within 90–100% of baseline. Material and Methods: Two hundred American Society of Anesthesiologists physical status -II parturients scheduled for CS with subarachnoid block (SAB) were randomly assigned to Group

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5

Gauchan, Sabin, Chitra Thapa, Sulav Acharya, and Anupa Khanal. "Hemodynamics following Prophylactic Phenylephrine Infusion in patients undergoing Cesarean Section under Spinal Anesthesia." Journal of Institute of Medicine Nepal 46, no. 1 (2024): 7–12. http://dx.doi.org/10.59779/jiomnepal.1298.

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Introduction Phenylephrine is considered the vasopressor of choice in hypotension associated with obstetric spinal anesthesia. But the dose and mode of administration that is effective yet safe in mother as well as fetus remains controversial. We studied the hemodynamics of parturients who received prophylactic infusion of phenylephrine 50µg/min following spinal anesthesia. MethodsPatients posted for elective cesarean section received a prophylactic phenylephrine infusion of 50µg/min immediately after spinal anesthesia for 30 minutes. Parturients were also co-loaded with lactated Ringer’s solu

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6

Sawaira, Sania Tanweer Khattak, Nayab Akhtar, Uzma Khan, and Wagma Basir. "Frequency of Low Apgar Score of New Born in Patient Having Abnormal Cardiotocography." Indus Journal of Bioscience Research 3, no. 4 (2025): 371–75. https://doi.org/10.70749/ijbr.v3i4.1015.

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Background: Cardiotocography (CTG) is used on a regular basis to check on fetal health, but it remains a topic of investigation for fetal-neonatal outcome correlation and low Apgar scores. Abnormal CTG patterns like fetal tachycardia, fetal bradycardia, and decelerations can signify fetal distress and are correlated with poor neonatal health. Objective: To determine the frequency of Low Apgar score in patient having abnormal cardiotocography. Study Design: Descriptive study. Duration and Place of Study: The study was conducted from March 2023 to September 2023 at the Department of Obstetrics a

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7

International, Journal of Medical Science and Innovative Research (IJMSIR). "Influence of ketamine on Maternal Hemodynamic, Awareness during Childbirth and Apgar Score of their Neonates." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 2 (2024): 74–78. https://doi.org/10.5281/zenodo.15372477.

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<strong>Abstract</strong> Ketamine has the potential to serve as a valuable analgesic for mothers undergoing obstetric surgery with providing conscious, although there have been raised concerns regarding the impact on newborns. This investigation sought to document the physiological and pharmacological impacts of ketamine on the vitality and activity of neonates directly following delivery as well as the magnitude of its influence on skin condition, pulse rate, respiration, and responsiveness to external stimuli. This study was carried out in the maternity hospitals located in the Al-Najaf Al-

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8

Ristovska, Sanja. "Respiratory Distress Syndrome (RDS) in Newborns with Hypoxic-Ischemic Encephalopathy (HIE)." PRILOZI 45, no. 1 (2024): 19–30. http://dx.doi.org/10.2478/prilozi-2024-0003.

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Abstract Respiratory distress syndrome (RDS) and hypoxic-ischemic encephalopathy (HIE) are frequent causes of death and disability in neonates. This study included newborns between January 2021 and July 2022 at the University Clinic for Gynecology and Obstetrics, Skopje. Up to date criteria for HIE/RDS for term and for preterm infants as well for the severity of HIE/RDS were used in a comprehensive analysis of cranial ultrasonography, neurological status, neonatal infections, Apgar score, bradycardia and hypotension, X-ray of the lungs, FiO2, acid-base status, assisted ventilation and use of s

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9

Pathak, Varuna, and Deep Shikha Sahu. "Relation between immediate postpartum APGAR score with umblical cord blood pH and fetal distress." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 12 (2019): 4690. http://dx.doi.org/10.18203/2320-1770.ijrcog20195185.

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Background: The one-minute Apgar score, proven useful for rapid assessment of the neonate, is often poorly correlated with other indicators of intrauterine well-being. Fetal asphyxia is directly associated with neonatal acidosis. Umbilical cord pH is best indicator of fetal hypoxemia and hypoxemia leads to neonatal acidosis. In today scenario, fetal distress is the leading indication of emergency cesarean section.Methods: A observational cross-sectional study conducted of one year between march 2017 to February 2018; of full-term obstetric patients undergoing emergency cesarean section for fet

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10

Rathoria, Richa, Ekansh Rathoria, Utkarsh Bansal, et al. "Study of risk factors and perinatal outcome in meconium stained deliveries from a district of Uttar Pradesh, India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 9 (2018): 3605. http://dx.doi.org/10.18203/2320-1770.ijrcog20183761.

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Background: The objective is to identify the risk factors of Meconium stained deliveries and evaluate the perinatal outcomes in Meconium Stained deliveries.Methods: This prospective observational study included those pregnant women who had completed 37 weeks of gestation, with singleton pregnancies with cephalic presentations and with no known fetal congenital anomalies. Among these, we selected 110 cases with Meconium stained amniotic fluid and they were compared with 110 randomly selected controls.Results: Regular antenatal visits were seen in 22.73 % of the cases while 77.27% cases had no p

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11

Rahman, Mahy Ragib, Novia Fransiska Ngo, and Ahmad Wisnu Wardhana. "The Relationship of Preeclampsia and Eclampsia, Antepartum Haemorrhage and Anemia Mother with Apgar Score <7 Babies Born in RSUD Abdoel Wahab Sjahranie Samarinda." Jurnal Kesehatan Pasak Bumi Kalimantan 5, no. 2 (2023): 156. http://dx.doi.org/10.30872/j.kes.pasmi.kal.v5i2.7680.

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Background: Everyday 7,000 babies die worldwide, with 2,4 million babies dying in the first month of life. While in Indonesia 19 deaths per 1000 live births with the main causes of neonatal death in 2017 were complication related to premature birth (asphyxia or difficulty breathing at birth), infections, and births defects. Meanwhile, in East Kalimantan, the highest cause of death was dominated by low birth weight (LBW) followed by asphyxia neonatorum. The examination that is always used in newborns by health workers to assess the occurrence of distress respiration neonatal is to assess the AP

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12

Axelsson, Paul, Anne-Louise Lykke Nielsen, and Christina Anne Vinter. "External cephalic version complicated by bradycardia and placental abruption– a case report." Danish Journal of Obstetrics and Gynaecology 2, no. 1 (2024): 62–66. http://dx.doi.org/10.56182/mp8dvk58.

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Introduction: Pregnancies with the fetus in breech position at term are routinely managed by offering external cephalic version to increase the likelihood of vaginal birth in the cephalic position and reducing the risk of cesarean delivery. Although complications from external cephalic version are infrequent, placental abruption is a rare but serious risk, occurring in 0.08% of attempts. Methods: This case report details the experience of a woman with an uncomplicated singleton pregnancy with fetal breech presentation at gestational age 37 weeks and 2 days, coming for an outpatient external ce

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13

Diedhiou, Moustapha, E. B. Ba, D. Barboza, et al. "Bupivacaine-Fentanyl vs Ropivacaine-Fentanyl: Evaluation of two Spinal Anesthesia Protocols for Emergency Cesarean Section." Journal of Drug Delivery and Therapeutics 10, no. 6-s (2020): 3–7. http://dx.doi.org/10.22270/jddt.v10i6-s.4403.

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Objective: Evaluation of the hemodynamic, respiratory and fetal side effects of two protocols for spinal anesthesia (P1: bupivacaine-fentanyl; P2: ropivacaine-fentanyl). Material and Method: Prospective pseudo-randomized study comparing two spinal anesthesia protocols for emergency cesarean section conducted in the operating room of the regional hospital center of Saint Louis in Senegal. Study duration was 4 months. We studied, age, indication for Caesarean section, medical and surgical history, P1 and P2 protocols, hypotension, bradycardia, Apgar scores at birth and at 5min. Univariate

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14

Muthalu, Arunkumar, Arthi Asokan, Vimala Ananthy, and Shoba Ujjwal. "Comparison of intravenous bolus doses of phenylephrine vs ephedrine along with crystalloid co-loading in the prevention of hypotension during spinal anesthesia for caesarean section." Indian Journal of Clinical Anaesthesia 8, no. 4 (2021): 537–42. http://dx.doi.org/10.18231/j.ijca.2021.116.

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Caesarean section was the first obstetrical operation that saves the life of the baby when normal delivery fails. Spinal anaesthesia is the most appropriate method for caesarean section. But hypotension is the most common side effect of it in patient with pregnant uterus. To compare the vasopressor effects of ephedrine and phenylephrine in ameliorating hypotension in elective caesarean delivery receiving crystalloid coloading, during intrathecal bupivacaine injection.: Study participants were randomly divided into two groups of 50 patients each. After subarachnoid block, all the parturients we

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15

Tabish Hussain, Asifa Anwar Mir, Jawad Zahir, and Pervaiz Minhas. "Efficacy of Nor-Adrenaline Vs Phenylephrine for the management of Spinal Hypotension among patients undergoing Cesarean Section." World Journal of Biology Pharmacy and Health Sciences 4, no. 2 (2020): 085–89. https://doi.org/10.30574/wjbphs.2020.4.2.0086.

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Introduction: Most of the Cesarean sections are conducted under regional anesthesia. Spinal anesthesia is the anesthesia of choice except where contraindications are encountered. Spinal anesthesia can lead to significant hypotension with relevant hemodynamic changes. Rescue medications frequently used to manage per-operatively include phenylephrine, ephedrine and noradrenaline. Phenylephrine is an α-agonist commonly used for the prevention and treatment of hypotension. The significant drawback is that it can cause bradycardia and reduced cardiac output. Recently, noradrenaline has been found a

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16

Soxhuku-Isufi, Alma, Vjollca Shpata, and Hektor Sula. "Maternal and Neonatal Effects of Vasopressors Used for Treating Hypotension after Spinal Anesthesia for Caesarean Section: A Randomized Controlled Study." Open Access Macedonian Journal of Medical Sciences 4, no. 1 (2015): 54–58. http://dx.doi.org/10.3889/oamjms.2016.003.

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AIM: The aim of the study was to examine whether ephedrine and phenylephrine were different in their efficacy for managing maternal hypotension and their effect of adverse maternal and neonatal outcome.METHODS: A double-blind randomized controlled study in healthy pregnant women ASA physical status 2, which underwent elective caesarian delivery under spinal anesthesia. Patients were randomized to receive an intravenous bolus of either phenylephrine (Ph group) or ephedrine (E group) immediately after the episode of hypotension after spinal anesthesia. Maternal and neonatal outcomes were recorde

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17

Nguyen, Thang Toan, Hao Canh Nguyen, Anh Thi Hong Nguyen, Trung Hieu Doan, and Quy Sy Ngo. "Comparison of intermittent boluses of noradrenaline vs. phenylephrine for spinal anesthesia induced hypotension during cesarean delivery." Anaesthesia, Pain & Intensive Care 27, no. 5 (2023): 562–66. http://dx.doi.org/10.35975/apic.v27i5.2312.

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Background and Objective: Maternal hypotension is a common consequence of spinal anesthesia for cesarean delivery (CD). A vasopressor is recommended in addition to adequate fluid loading to raise mean arterial pressure in pregnant women. Phenylephrine, a pure α–adrenergic receptor agonist, is the first-line agent to manage it. However, phenylephrine is associated with dose-dependent reflex bradycardia and decreased cardiac output. Noradrenaline is suggested as an alternative due to its mild beta-adrenergic effect, which results in a greater heart rate and cardiac output than phenylephrine. We

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18

SpOG(K)-KFM, Prof Dr dr Hj Yusrawati, Nanda Tri Wahdini, Hauda El Rasyid, and Muhammad Riendra. "A Case of Prenatal Diagnosis of Congenital Total AV Block on VSD and PDA with Ultrasound." Journal Obgin Emas 5, no. 2 (2021): 244–53. http://dx.doi.org/10.25077/aoj.5.2.244-253.2021.

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Objective : To report the diagnosis and management of congenital total AV block on VSD and PDA in pregnancy.Method : A case reportCase : A 37-year-old multiparous woman G4P3A0H2 24- 25 weeks of preterm pregnancy with fetal bradycardia, VSD, PDA with ultrasonography and CTG results was FHR 70 bpm. At 37- 38 weeks of pregnancy, termination of pregnancy was performed by cesarean delivery with preparation for complication of fetal AV block. A male baby was born with weight 2600 gram and APGAR score of 8/9. Immediate echocardiography result was situs solitus, VSD PM LR shunt, PDA LR shunt, good l

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19

Yusrawati, Yusrawati, Nanda Tri Wahdini, Hauda El Rasyid, and Muhammad Riendra. "A Case of Prenatal Diagnosis of Congenital Total AV Block on VSD and PDA with Ultrasound." Andalas Obstetrics And Gynecology Journal 5, no. 2 (2021): 252–61. http://dx.doi.org/10.25077/aoj.5.2.252-261.2021.

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Objective : To report the diagnosis and management of congenital total AV block on VSD and PDA in pregnancy.Method : A case reportCase : A 37-year-old multiparous woman G4P3A0H2 24- 25 weeks of preterm pregnancy with fetal bradycardia, VSD, PDA with ultrasonography and CTG results was FHR 70 bpm. At 37- 38 weeks of pregnancy, termination of pregnancy was performed by cesarean delivery with preparation for complication of fetal AV block. A male baby was born with weight 2600 gram and APGAR score of 8/9. Immediate echocardiography result was situs solitus, VSD PM Lïƒ R shunt, PDA Lïƒ R shunt, go

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20

Garg, Heena, Vishnu Narayanan M R., Puneet Khanna, and Bharat Yalla. "Comparison of Phenylephrine Bolus and Infusion Regimens on Maternal and Fetal Outcomes During Cesarean Delivery: A Systematic Review and Meta-Analysis." Anesthesia & Analgesia 139, no. 6 (2024): 1144–55. http://dx.doi.org/10.1213/ane.0000000000007156.

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BACKGROUND: A systematic review and meta-analysis was conducted to compare phenylephrine boluses versus prophylactic infusion in parturients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia on feto-maternal outcomes. METHODS: Medline, Embase, Cochrane, and US Clinical registry databases were searched. Studies comparing phenylephrine boluses (both therapeutic and prophylactic) with infusion (both fixed- and variable-rate) assessing various feto-maternal outcomes were included. The primary outcome was the incidence of maternal hypotension. Secondary maternal outco

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21

Bandyopadhyay, Anjishnujit, Chhavi Sawhney, Partha Haldar, and Sharmishtha Pathak. "Effect of prophylactic phenylephrine versus norepinephrine on foeto-maternal outcomes in caesarean delivery under neuraxial anaesthesia: A systematic review and meta-analysis with trial sequential analysis." Indian Journal of Anaesthesia 69, no. 7 (2025): 638–49. https://doi.org/10.4103/ija.ija_1063_24.

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Background and Aims: The prevention of hypotension in parturients scheduled for caesarean section is of utmost importance for improving foeto-maternal outcomes. We compared the prophylactic use of phenylephrine (PE) and norepinephrine (NE) on foeto-maternal outcomes in women undergoing caesarean delivery under neuraxial anaesthesia. Umbilical artery (UA) pH was the primary objective, and umbilical vein (UV) pH, APGAR scores, incidence of bradycardia, hypotension, and hypertension were secondary objectives. Methods: PubMed, EMBASE, Web of Science, Google Scholar, and CENTRAL databases were sear

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22

Kumble, Ali, Abhishek K. Phadke, Poonam Raikar, and Anciline Siriac. "Otocephaly revealed: A case study of a rare facial anomaly." Indian Journal of Case Reports 11, no. 1 (2025): 14–15. https://doi.org/10.32677/ijcr.v11i1.4827.

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Otocephaly (OC) is a rare malformation characterized by the association of agnathia (agenesis of mandible) or mandibular hypoplasia, melotia (anteromedial malposition of ears), microstomia (small mouth), aglossia or microglossia (absent or rudimentary tongue). We present an extremely preterm/very low birth weight/female baby born to a G2P1IUD1 mother. The baby did not cry at birth. APGAR was 3 at 1 min and 1 at 5 min. On examination, the baby had multiple craniofacial abnormalities including an absent mandible, small mouth, rudimentary tongue, ventromedian malposition of ears, and bilateral ch

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23

Haque, M. Masudul, Mohammad Abdul Aleem, Pervez Altaf Hossain, Md Abu Baker Siddique, and Atiqul Islam. "Ephedrine versus Phenylephrine: Prevention of Hypotension during Spinal Anaesthesia for Cesarean Section and Effects on the Fetus." Journal of the Bangladesh Society of Anaesthesiologists 30, no. 1 (2017): 41–47. http://dx.doi.org/10.3329/jbsa.v30i1.65841.

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Background: Hypotension during spinal anaesthesia for cesarean section is secondary to the sympathetic blockade and aorto-caval compression by the uterus and it can be deleterious to both the fetus and the mother. Ephedrine and phenylephrine improve venous return after sympathetic blockade during the spinal anaesthesia. Aim: The aim of this study was to compare intravenous bolus doses of phenylephrine and ephedrine in preventing and treating hypotension in spinal anaesthesia for caesarean section and the effect of vasopressors on fetal outcome in terms of Apgar score. Materials and Methods: To

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24

Nagao, Takeshi, Erisa Kuriyama, Ami Sato, and Michiko Yamanaka. "Velamentous cord insertion ruptured during labour leading to acute fetal blood loss." BMJ Case Reports 14, no. 4 (2021): e240245. http://dx.doi.org/10.1136/bcr-2020-240245.

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Umbilical cord rupture (UCR) in utero is a very rare and critical emergency that can cause fetal death within minutes. A 38-year-old nulliparous woman was admitted at 39 weeks in labour. Sudden watery vaginal discharge and bleeding with a rapid drop in the fetal heart rate to 60 beats/min necessitated an emergency caesarean section. A male infant weighing 2632 g was delivered 21 min after the onset of bradycardia; Apgar scores were 0 and 1 at 1 and 5 min, respectively. He was extremely pale; the umbilical arterial blood pH was 6.89 and haemoglobin was 9.0 g/dL. The umbilical cord had a velamen

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Osmani, Shaik Gulam, Manasa Acharya, Shaila S. Kamath, Suresh Y.V, and Kavya Prabhu. "Comparison of prophylactic phenylephrine versus noradrenaline boluses for hemodynamic stability during elective cesarean delivery under spinal anesthesia–an observational study." Anaesthesia, Pain & Intensive Care 26, no. 2 (2022): 168–74. http://dx.doi.org/10.35975/apic.v26i2.1818.

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Background: Profound hypotension and bradycardia following spinal anesthesia (SA) during cesarean delivery (CD) result in catastrophic maternal and fetal consequences. Phenylephrine with its appealing α agonist property proved to be a valid vasopressor for correction of hypotension during SA but with side effects like reflex bradycardia and fall in cardiac output. Noradrenaline is a rational substitute to phenylephrine due to its mild β and prominent α adrenergic properties, but is reserved as an inotrope mainly for medical crisis management. We conducted a comparative observational study of n

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26

Baytaş, Volkan, Süheyla Karadağ Erkoç, Menekşe Özçelik, et al. "A Randomized, Double-Blind, Graded Dose-Response Study of Norepinephrine Administration for Prevention of Post-Spinal Hypotension during Elective Cesarean Delivery." Journal of Clinical Medicine 12, no. 20 (2023): 6437. http://dx.doi.org/10.3390/jcm12206437.

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Norepinephrine has been recently introduced for prophylaxis against post-spinal hypotension during cesarean delivery; however, no data are available regarding its optimum dosing scheme. The primary objective of this study is to compare three different infusion and bolus dose combinations of norepinephrine for prophylaxis against post-spinal hypotension during cesarean delivery. This randomized, double-blind study was performed between February 2021 and May 2022. The study protocol was registered at Clinicaltrials.gov with the identification number NCT04701190. A total of 192 parturients were e

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Abdur, Rehman Dr Khalid Hussain Dr. Manzara Mudassar. "ASSOCIATION OF VENOUS BOLUS QUANTITIES OF PHENYLEPHRINE AND EPHEDRINE TO CURE HYPOTENSION AFTERWARDS SPINAL ANESTHESIA." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 06 (2019): 12363–67. https://doi.org/10.5281/zenodo.3250755.

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<strong><em>Background: </em></strong><em>Hypotension succeeding spinal anesthesia (SA) for cesarean distribution might got significant results for parturient also can disturb newborn baby result. </em> <strong><em>Purpose:</em></strong><em> The main purpose of our current research remained to associate venous bolus quantities of phenylephrine also ephedrine to cure hypotension afterwards spinal anesthesia for cesarean unit also consequence of vasopressors on dangerous consequence in rapports of Apgar score.</em> <strong><em>Methodology: </em></strong><em>The overall 210 parturient satisfying

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Narendra, Thadu, Kumar Suggala Kiran, and Anusha T. "Comparative Efficacy of Phenylephrine and Mephentermine in Mitigating Hemodynamic Responses to Oxytocin Administration during Elective Cesarean Section." International Journal of Pharmaceutical and Clinical Research 16, no. 12 (2024): 1711–15. https://doi.org/10.5281/zenodo.14636804.

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<strong>Introduction:</strong> Cesarean sections performed under spinal anaesthesia are associated with maternal hypotension, exacerbated by oxytocin administration during surgery. Effective management of these hemodynamic changes is crucial for maternal and fetal safety. Phenylephrine, a selective α1-adrenergic agonist, and mephentermine, a mixed-action sympathomimetic, are commonly used vasopressors. However, comparative data on their efficacy in mitigating oxytocin-induced hemodynamic responses during cesarean sections is limited. <strong>Materials and Methods:</strong>&nbsp

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Kapote, Deepali S., Apeksha M. Mohite, and Anam Syed. "Comparative analysis of maternal and fetal outcome in meconium stained amniotic fluid and clear liquor in primigravida." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 2 (2020): 482. http://dx.doi.org/10.18203/2320-1770.ijrcog20200061.

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Background: The present study was undertaken to evaluate the significance of MSAF and its fetal outcome in parturients.Methods: A total of 121 pregnant women who had completed more than 37 weeks of gestation with live singleton pregnancy, spontaneous onset of labor and at term with adequate pelvis were included in the study. All (121) low risk primigravida with MSAF were studied to identify maternal and fetal outcome and compared with equal number of cases with clear amniotic fluid. Meconium stained cases were clinically classified into two groups- thin (54 cases) and thick (67 cases). MSAF on

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Choudhury, Arpita, Shalini Das, Sankar Roy, Bani Parvati Magda Hembrom, and Dipasri Bhattacharya. "Comparison of intermittent intravenous bolus of phenylephrine and noradrenaline in management of spinal anesthesia induced hypotension in elective cesarean section: A randomized controlled trial." Indian Journal of Clinical Anaesthesia 12, no. 1 (2025): 139–44. https://doi.org/10.18231/j.ijca.2025.021.

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Though Noradrenaline infusion is showing promising results for management of spinal anaesthesia-induced hypotension, there are very few studies that evaluated intermittent intravenous (i.v) bolus dose of inj. Noradrenaline. So, we aimed to compare intermittent i.v. bolus of phenylephrine and noradrenaline in management of spinal anaesthesia-induced hypotension in elective LSCS.This randomized controlled study was conducted in obstetrics operation theatre from August 2022 to April 2023. Intermittent I.V. bolus dose of Phenylephrine (Group A) was compared with intermittent I.V. bolus dose of Nor

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Rajan, Niranjana, Ramayee Ramanathan, and Vijayakumar Manam. "A successful pregnancy outcome in a patient with cardiac permanent pacemaker." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 14, no. 2 (2025): 645–48. https://doi.org/10.18203/2320-1770.ijrcog20250210.

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We present a case of 31 years old Gravida 2 Abortion 1 at 25 weeks of gestation with history of congenital heart disease- Left aorto-ventricular tunnel, for which she had intracardiac repair at 7 years of age. She had bradycardia, syncopal attacks, diagnosed as complete heart block at 26 yrs of age and had permanent pacemaker implantation had come for antenatal care. Echocardiogram showed ejection fraction of 30%, global hypokinesia of left ventricle and moderate aortic regurgitation. Patient was asymptomatic. As per cardiologist opinion, started on Tab. Amiodarone 100mg once daily on alternat

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Chaudhry, Shahid Adalat, Mubashar Iqbal, Muhammad Nadeem Khan, Aurooj Fatima, Hina Zubair, and Madiha Haroon. "A Comparative Study of Ephedrine and Phenylephrine in Averting Hypotension during Cesarean Section under Spinal Anesthesia." Pakistan Journal of Medical and Health Sciences 16, no. 1 (2022): 967–70. http://dx.doi.org/10.53350/pjmhs22161967.

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Maternal haemodynamic variations are communal during caesarean section by spinal anesthesia. Several measures are adopted to treat hypotension. The aim of this study is to compare the effectiveness of phenylephrine and ephedrine in treating and preventing hypotension during C-section by spinal anesthesia and its outcome on the condition of the fetus. Place and Duration: In the Anesthesia department of Divisional Headquarter teaching Hospital Mirpur Azad Kashmir for six-months duration from July 2021 to December 2021. Methods: 120 total ASA grade-I patients with normal single pregnancy over 36

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Degiacomo, Jessica, and Sherry Luedtke. "Neonatal Toxicity From Escitalopram Use In Utero: A Case Report." Journal of Pediatric Pharmacology and Therapeutics 21, no. 6 (2016): 522–26. http://dx.doi.org/10.5863/1551-6776-21.6.522.

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Selective serotonin reuptake inhibitor (SSRI) exposure during pregnancy can result in symptoms of serotonin syndrome or serotonin withdrawal. In contrast to other SSRIs, reports of serotonin behavioral syndrome following in utero exposure to escitalopram and citalopram are limited. We describe a case of suspected toxicity following in utero exposure to 20 mg escitalopram throughout pregnancy. The infant was transferred to our neonatal intensive unit at 9 hours of life for further evaluation of lethargy, weak cry, bradycardia, and non-reactive pupils. Hypoxic ischemic encephalopathy was suspect

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Sood, Reena, Harmandeep Kaur, Gaurav Mohan, and Madhu Nagpal. "Maternal congenital complete heart block in pregnancy: a rare case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 8 (2020): 3502. http://dx.doi.org/10.18203/2320-1770.ijrcog20203351.

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Complete heart block comprises complete absence of AV conduction - none of the supraventricular impulses are conducted to the ventricles. Perfusing rhythm is maintained by a junctional or ventricular escape rhythm. Typically, the patient will have severe bradycardia with independent atrial and ventricular rates. The incidence is 1 in 15,000 to 20,000 live births. Authors present the case report of a primigravida, aged 30 years who presented with amenorrhoea of 35 weeks. She was diagnosed as complete heart block by cardiologist. She had no history of syncopal attacks during childhood or antenat

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Petrikovsky, Boris M., Lali Sichinava, and Steven Swancoat. "Can Fetal Heart Rate Responses to Maternal Exercise Be Used for Antepartum Surveillance?" Journal of Diagnostic Medical Sonography 34, no. 5 (2018): 342–45. http://dx.doi.org/10.1177/8756479318776218.

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The contraction stress test (CST) is currently the only modality used to test for placental insufficiency. It is rarely used due to possible complications. We propose a new test to assess placental reserves by measuring fetal heart rate (FHR) fetal responses to maternal exercise (FRME). A cohort of 640 term patients underwent FRME for accepted clinical indications. There was a total of 1680 tests, performed using a motorized treadmill in a moderate exercise regimen. Monitoring was provided by using standard Philips equipment (Avalon CTS and FM40). FRME was interpreted as negative (absence of d

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Amish, Kumar, Kant Rishi, and Verma Rajesh. "A Hospital-Based A Prospective Comparative Assessment of the Analgesic Efficacy of Intrathecal 1% 2-Chloroprocaine with or Without Fentanyl in Elective Caesarean Section." International Journal of Pharmaceutical and Clinical Research 14, no. 11 (2022): 983–89. https://doi.org/10.5281/zenodo.13273392.

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<strong>Aim:</strong> To compare the analgesic efficacy and safety of intrathecal fentanyl (25 µg) as an adjuvant to low dose 1% 2-CP (30 mg) in parturients undergoing caesarean section. <strong>Methodology:</strong> This prospective, double-blind, randomized, comparative study was conducted in Department of Anesthesia and critical care, Patna Medical college and hospital, Patna, Bihar for one year. 100 participants with term pregnancy (≥36 weeks), belonging to the American Society of Anesthesiologists (ASA) physical status II, aged between 18 and 35 years, scheduled to

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Yong-Din, Kim, N. Nadyrkhanova, R. Tkachenko, Yu Kulichkin, and F. Nishanova. "Possibility to use quanadex (dexmedetomidine) for caesarean section in patients with pre-eclampsia." Pain medicine 6, no. 4 (2022): 28–36. http://dx.doi.org/10.31636/pmjua.v6i4.3.

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A prospective, doubleblind, randomized, controlled clinical trial was conducted at the Republican Specialized Scientific and Practical Medical Center of Obstetrics and Gynecology of the Ministry of Health of the Republic of Uzbekistan. The inclusion criteria for pregnant women in the study was preeclampsia. All women were divided into 2 groups. In group I, premedication was performed on the table with sibazon 5 mg. In group II, starting from the moment of premedication, 0.5 µg/kg of quanadex (Yuriya Pharm) was administered intravenously for 15 minutes. The maintaining dose was 0.5–0.8 µg

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Sigdel, Rohini, Maya Lama, Sanish Gurung, et al. "Hemodynamic effects of right pelvic wedge in patients undergoing elective cesarean section under spinal anesthesia." Medical Journal of Pokhara Academy of Health Sciences 1, no. 2 (2018): 70–74. http://dx.doi.org/10.3126/mjpahs.v1i2.23394.

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Background: Several methods have been used to prevent post spinal hypotension including preloading, co-loading, use of vasopressors, placement of pelvic wedge, lumbar wedge and tilting of operating table in parturients undergoing cesarean section. We conducted a randomized controlled study to determine the hemodynamic effects of a standard pelvic wedge placed below the right hip immediately after the spinal block till the delivery of baby. Methods: One hundred consenting women undergoing elective cesarean section under spinal anesthesia were randomly allocated to wedge group (N=50) and c

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Aviral, Srivastava, Thakur Yeshli, Sinha Jaya, and Sanwatsarkar Sadhana. "Assessment and Comparison of Effect of Combination of (1%) Chloroprocaine and (0.5%) Hyperbaric Bupivacaine with Fentanyl and (1%) Chloroprocaine and (0.5%) Isobaric Ropivacaine with Fentanyl in LSCS." International Journal of Pharmaceutical and Clinical Research 15, no. 6 (2023): 626–36. https://doi.org/10.5281/zenodo.12193040.

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<strong>Introduction: </strong>Sub arachnoid block (SAB) provides a rapid and reliable anaesthetic technique for caesarean section. The principal side effects of SAB are a reduction in maternal blood pressure and hence uteroplacental blood flow; inadequate effect leading to maternal pain and conversion to general anaesthesia. Decreasing dose of intrathecal local anaesthetic (LA) improves cardiovascular stability. Addition of opioid allows safe reduction of LA dose with equal success and less severe side effects.<sup>1</sup> The present study was done to evaluate combination of (1%) C

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Tarasiuk, О. В., Anastasiya Babintseva, Dariia Kostiukova, and I. V. Golovatiuk. "COMPREHENSIVE NEUROMONITORING OF THE NEWBORN WITH MANIFESTATIONS OF SEVERE ASPHYXIA AND THERAPEUTIC HY." Neonatology, surgery and perinatal medicine 11, no. 1(39) (2021): 65–72. http://dx.doi.org/10.24061/2413-4260.xi.1.39.2021.9.

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Birth asphyxia is a separate nosological form characterized by clinical symptoms ofcardiorespiratory and neurological depression of a newbornwith possible subsequent development of encephalopathyand multiorgan dysfunction, as well as laboratory signsof side effects of fetal hypoxia before or during childbirth(significant metabolic or mixed acidosis in umbilical cordblood gases). The current method of treatment of childrenwith manifestations of asphyxia is therapeutic hypothermia,that should be accompanied by continuous monitoring ofthe patient's cerebral functions.The article presents a clinic

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Baloch, Fozia, Falak Abro, Qurat-Ul-Ain Khalid, and Prem Chand. "Perinatal Stroke; Risk Factors and Outcome. A Study from Aga Khan University Hospital Karachi." Pakistan Armed Forces Medical Journal 72, no. 1 (2022): 215–19. http://dx.doi.org/10.51253/pafmj.v72i1.4863.

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Objective: To determine the frequency, risk factors and the outcomes of a perinatal stroke. Study Design: Cross-sectional study. Place and Duration of Study: Neonatal Intensive Care Unit, Department of Pediatrics, Aga Khan University Hospital, Karachi Pakistan, from Jan to Dec 2019. Methodology: Neonates with perinatal stroke confirmed on the neuroimaging, were included in the study. The primary outcomes were risk factors, divided into 3 groups, maternal, placental and neonatal. The secondary outcome was the condition at the time of the discharge. Results: A total of 58

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Shahid Khan, Zil Maurij Fiaz, Muhammad Haroon Anwar, Rana Imran Sikander, Ahmad Ali, and Kiran Ayesha. "Comparison of Phenylephrine infusion vs Nor-epinephrine Infusion on Maternal Hemodynamics and Neonatal Outcomes During Elective Lower Segment Caesarean Section under Sub-Arachnoid Block." Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University 20, no. 1 (2024): 74–79. http://dx.doi.org/10.48036/apims.v20i1.919.

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Objective: To compare the efficacy of Phenylephrine and Nor-epinephrine IV infusions in maintaining maternal hemodynamics during EL-LSCS. Methodology: This randomized control trial study was conducted department of Anesthesia and Critical Care Medicine, Pakistan Institute of Medical Sciences (PIMS), Islamabad from March, 2023 to November, 2023. This study enrolled 62 patients fulfilling the inclusion criteria i.e., patient of age 18-45 years undergoing elective LSCS under SAB were enrolled in the study. While those having hypertension, pre-clampsia, eclampsia, pre-existing bradycardia, fetal d

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Alhawsawi, Ebtihal, Nedaa Bahkali, Sarah Aljadani, Abdulaziz Jambi, Alhanouf Almwled, and Samera Al Basri. "Implementation of a crash cesarean section policy and its impact on maternal and neonatal outcomes at King Abdulaziz University Hospital: A retrospective study." Medicine 103, no. 48 (2024): e40645. http://dx.doi.org/10.1097/md.0000000000040645.

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A typical surgical technique for pregnant women with potentially fatal problems affecting the mother or fetus is an emergency cesarean section (ECS). The decision-to-delivery interval (DDI) for ECS should be within 30 minutes. The objective of this study was to investigate crash ECS indications and effects on maternal and neonatal outcomes. In this retrospective study, all women undergoing crash cesarean section (CS) at Obstetrics and Gynecology department at King Abdulaziz University hospital, Jeddah, Saudi Arabia during 2022 and 2023 were evaluated. Data about demographic and obstetric chara

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Habasha, Zainab Faisal. "Synergistic effect of inthrathecal fentanyl and bupivacaine in spinal anesthesia for cesarean section in Baghdad city." International Journal Of Community Medicine And Public Health 9, no. 6 (2022): 2462. http://dx.doi.org/10.18203/2394-6040.ijcmph20221521.

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Background: Potentiating the effect of intrathecal local anesthetics drugs by addition of intrathecal opiods for intra-abdominal surgeries had been used lately. In this study by addition of fentanyl, we tried to minimize the dose of bupivacaine thereby reducing the side effect caused by higher doses of intrathecal bupivacaine in cesarean section, and to improve the quality of block.Methods: Study was performed on sixty patients underwent cesarean section they were divided into 6 groups as B10, B 12.5, B15 mg of bupivacaine and FB10, FB12.5, FB15 received a combination of 25 µg intrathecal fent

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Mohamed, Sherif Abdullah, Ahmed Elsonbaty, and Mohamed Elsonbaty. "A Comparison between Intrathecal Nalbuphine and Fentanyl for Intraoperative Pain Management during Uterine Exteriorization in Cesarean Section: A Randomized Controlled Trial." Open Access Macedonian Journal of Medical Sciences 9, B (2021): 533–40. http://dx.doi.org/10.3889/oamjms.2021.6531.

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BACKGROUND: Uterine exteriorization during cesarean section is linked to an increased incidence of visceral pain. AIM: This study explored the ability of intrathecal nalbuphine to alleviate this accompanied pain to be used as an effective safer alternative to fentanyl, as there is almost no study compared between these agents to alleviate visceral pain induced by uterine exteriorization. METHODS: This double-blinded randomized controlled research was done on 135 cases subjected to cesarean section with exteriorization of the uterus. Patients were randomized equally into F, N, and C groups whic

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Constantin, Ioana-Luciana, Elena Rotaru, Delia Stratone, et al. "A successful interdisciplinary collaboration for the management of pneumoperitoneum and pericardial effusion in a premature newborn." Romanian Journal of Pediatrics 71, no. 3 (2022): 148–52. http://dx.doi.org/10.37897/rjp.2022.3.7.

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Objectives. Percutaneously central catheters are typically used in neonatal intensive care units (NICU) to provide parenteral nutrition and drug therapy administration. Their use is associated with specific complications: occlusions, infections, thrombosis, rupture, and migration, including rare life-threatening conditions such as pericardial effusion and cardiac tamponade. Material and methods. We present the case of a patient hospitalized in the Neonatology Department of “Sf. Andrei” County Clinical Emergency Hospital of Constanta, diagnosed with cardiac tamponade at 18 days of life. Outcome

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Zakaria, Zahar Azuar, and Maria Muhammad. "Decision to delivery interval in cesarean delivery for suspected fetal distress: the risk factors and outcomes." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 12, no. 6 (2023): 1532–37. http://dx.doi.org/10.18203/2320-1770.ijrcog20231516.

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Background: This study was to evaluate the differences in the neonatal outcomes after caesarean sections (CS) for suspected fetal distress in groups with decision to delivery interval (DDI) of 30 minutes or less and longer than 30 minutes. Factors associated with these intervals were also investigated. Methods: Data were retrospectively collected from all emergency caesarean deliveries for fetal distress in 2021. Maternal demographic data, the procedure characteristics and the neonatal outcomes were analyzed according to the DDI groups; 30 minutes or less and more than 30 minutes. Time interva

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Chandraleela Sundararajan, Chinthavali Sujatha, and Arthi Asokan. "Comparison of norepinephrine and phenylephrine boluses during spinal anesthesia for cesarean delivery." Asian Journal of Medical Sciences 13, no. 10 (2022): 54–58. http://dx.doi.org/10.3126/ajms.v13i10.47232.

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Background: Cesarean sections are frequently carried out under spinal anesthesia (SA) to reduce the risk of neonatal drug transfer and airway difficulties associated with general anesthesia. Maternal hypotension is a typical consequence following SA, despite sufficient fluid loading. Aims and Objectives: The aim of this study was to evaluate the efficacy of norepinephrine and phenylephrine in treating spinal hypotension caused by cesarean delivery. Materials and Methods: This hospital-based interventional study was carried out at Sri Venkateswaraa Medical College Hospital and Research Centre,

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Deepali, Rahate Gomase. "A Comparative Study on the Use of Prophylactic Intravenous Ephedrine to Reduce Hypotension During Spinal Anaesthesia for Caesarean Sections." International Journal of Toxicological and Pharmacological Research 12, no. 12 (2022): 263–69. https://doi.org/10.5281/zenodo.7948304.

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<strong>Background: </strong>The most frequently used and favoured method for caesarean birth is spinal anaesthesia. It is however linked to hypotension, which is harmful to the mother and foetus. The goal of the study is to ascertain how bolus intravenous ephedrine can reduce spinal-induced hypotension. Due to decreased uteroplacental blood flow, regional anaesthetic for Caesarean delivery is linked to a high prevalence of maternal hypotension and may cause foetal acidemia. Preloading with fluids, avoiding aortocaval compression, and giving vasopressor medications are all common ways to preve

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Mota-Rojas, D., J. Martinez-Burnes, D. Villanueva-Garcia, et al. " Animal welfare in the newborn piglet: a review." Veterinární Medicína 57, No. 7 (2012): 338–49. http://dx.doi.org/10.17221/6262-vetmed.

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The objective of this review is to integrate clinical findings and laboratory analyses in such a way to improve the welfare of newborn piglets and achieve better prognoses of neonatal viability. Deaths during the intrapartum period account for a significant proportion of pre-weaning mortality in farms worldwide. Piglets which die during parturition generally have normal size and typically lack gross lesions at post-mortem examination. However, circulatory abnormalities in the umbilical cord help in assessing piglet viability. Cord lesions can be classified as normal (adhered), oedematous, cong

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