Дисертації з теми "Brea (famille)"
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1
Perottino, Serge. "Transcendance et subjectivité : les problèmes de la création : Brea, Van Gogh, Chagall." Nice, 1989. http://www.theses.fr/1989NICE2009.
2
Neal, Ronita. "Unemployment and the family : the effects of unemployment of the family "bread-winner" /." Title page, contents and abstract only, 1988. http://web4.library.adelaide.edu.au/theses/09ARPS/09arpsn342.pdf.
3
Hickson, Kara. "Work-Family Conflict and Performance Evaluations: Who Gets a Break?" Doctoral diss., University of Central Florida, 2008. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4047.
Анотація:
Forty percent of employed parents report that they experience work-family conflict (Galinsky, Bond, & Friedman, 1993). Work-family conflict (WFC) exists when role pressures from the work and family domains are mutually incompatible. WFC is associated with decreases in family, job, and life satisfaction and physical health; intention to quit one's job; and increases in workplace absenteeism. Women may be more impacted by WFC than men, as women report completing 65-80% of the child care (Sayer, 2001) and spend 80 hours per week fulfilling work and home responsibilities (Cowan, 1983). Research suggests that WFC can be reduced with social support, such as co-workers providing assistance when family interferes with work (Carlson & Perrewe, 1999). It is unclear whether parents 'get a break' or are penalized by co-workers. The purpose of the present study was to examine co-workers' reactions to individuals who experience WFC. Based on sex role theory and attribution theory, it was predicted that women, people who experience family interference with work, and those who have more control over the work interference would be helped less and evaluated more poorly on a team task than men, people who experience non-family related work interference, and those who have less control over the work interference. A laboratory experiment was conducted in which participants signed up for a team-based study. The teammate was a confederate who was late for the study. Teammate control over the tardiness (unexpected physician's visit versus forgotten physician's appointment), type of work conflict (self- versus family-related), and gender of the teammate were manipulated. After learning about the reasons for the tardiness of their teammate, the 218 participants (63% female; 59% Caucasian) decided whether to help the late teammate by completing a word sort task for them or letting the late teammate make up the work after the experiment. When the teammate arrived, the participants completed a team task and then evaluated the task performance of their teammate. None of the hypotheses were confirmed in this study. However, exploratory analyses showed that people who had more control over the tardiness were rated lower than people who had less control over the tardiness. Contrary to expectations, exploratory analyses also showed that men rated women who were late to the study for a family-related reason higher than women who were late due to a self-related reason. These findings suggest that male co-workers may give women a break when they experience family interference with work. Implications for future research and practice are discussed.Ph.D.
Department of Psychology
Sciences
Psychology PhD
4
Hickson, Kara C. "Work-family conflict and performance evaluations who gets a break? /." Orlando, Fla. : University of Central Florida, 2008. http://purl.fcla.edu/fcla/etd/CFE0002136.
5
Theobald, Delphine. "Marriage, family break-up and offending : results from the Cambridge study in delinquent development." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609821.
6
Kechik, Joy E. "Comparing Family Sharing Behaviors in BRCA Carriers with PALB2 Carriers." Scholar Commons, 2019. https://scholarcommons.usf.edu/etd/7825.
Анотація:
Identifying individuals with hereditary cancer predisposition can improve health outcomes for patients and their family members through early cancer detection and prevention strategies. Prior research about family sharing of genetic test results among those with hereditary breast cancer has overwhelmingly been limited to the BRCA1 and BRCA2 genes. The present study sought to compare family sharing behaviors in women with pathogenic BRCA variants to women with pathogenic variants in the more recently identified and characterized PALB2 gene. A total of 18 BRCA carriers and 13 PALB2 carriers were interviewed about family sharing practices using a semi-structured guide based on the Integrated Behavioral Model. Barriers and facilitators to family sharing were similar for both BRCA and PALB2 carriers, with logistical difficulties and emotional struggles related to anticipated negative reactions from relatives being the most salient barriers. The most important facilitators were: attitude that sharing enables health protection, provider recommendation, strong family relationships, confidence in sharing basic information, knowledge of what to share and how to share, and belief that sharing is highly important. Given similar attitudes, norms, and control beliefs related to family sharing, similar, but tailored interventions may be effective at increasing family disclosures among both groups. Such interventions should involve a discussion of patients’ attitudes towards sharing with healthcare providers to strengthen motivations and address barriers and provision of informational resources to increase confidence and knowledge. Family sharing resources should clearly specify which relatives need to be informed, why sharing is important, and how at-risk relatives may benefit.
7
Snyder, Justine A. B. A. "Tools and Strategies That a BRCA Positive Population Considers to be Useful in the Result Disclosure Process to Family Members." University of Cincinnati / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1337351846.
8
Hardie, Michael L. "Using Hamlet and Peter Pan: Family Issues, Ghosts, and Memory in Bret Easton Ellis's Lunar Park." ScholarWorks@UNO, 2016. http://scholarworks.uno.edu/td/2233.
9
Ingleby, Lisa Jayne. "Clinical genetics in a palliative care setting : a qualitative exploration of the barriers and levers staff report when discussing family risk of BRCA 1 and BRCA 2 mutations." Thesis, University of Leicester, 2015. http://hdl.handle.net/2381/35952.
Анотація:
Palliative care is a term which refers to the services provided to those with incurable, life-limiting illnesses. In addition, the specialism of clinical genetics is increasingly able to identify individuals who are genetically predisposed to illness, particularly Breast Cancer (BRCA) 1 and 2 mutations which increase the chance of developing breast or ovarian cancer. A range of preventative and screening interventions are available. These issues have the potential for psychological consequences for patients at the end of life, their families and for the clinicians raising these issues with them. The review of the literature examined the qualitative evidence-base regarding the impact of caring for the dying on hospice nurses. A qualitative metasynthesis of 11 articles was carried out and identified two main themes and eight subthemes. These reflected what nurses’ considered to be core elements of their work with patients and a primary driver to facilitate a ‘good death’. Further to this, factors which either facilitated or impeded achieving this aim were identified to act to either replenish or drain nurses’ resources. Recommendations for how to best meet these identified needs were made with potential benefit for both nurses and patients. The research consisted of interviews with 13 palliative care staff to explore issues pertaining to the discussion of genetic risk in a palliative care setting. Thematic Analysis (TA) was used to develop four main themes and seven subthemes identifying the main considerations for participants regarding the inclusion of conversations about potential genetic risk of BRCA 1 and 2 mutations within their general practice. These formed the basis of recommendations which may be useful to services as they adapt to novel clinical interventions within their care for dying patients. The critical appraisal provides a reflective account of the experience of undertaking research and limitations of the research are discussed.
10
Guérin, Claire. "Analyse des facteurs de transcription de la famille NAC chez le blé tendre (Triticum aestivum L.) et leur implication dans la réponse à des stress abiotiques." Thesis, Université Clermont Auvergne (2017-2020), 2019. http://www.theses.fr/2019CLFAC014/document.
Анотація:
Le blé tendre, Triticum aestivum, est une des céréales les plus cultivées dans le monde. Le changement climatique qui se développe actuellement contraint fortement les cultures et altère leur rendement. La compréhension des mécanismes de réponse du blé tendre aux stress abiotiques est donc une problématique d’actualité. Plusieurs grandes familles de facteurs de transcription, dont la famille NAC,interviennent dans le développement de la plante et dans sa réponse aux stress environnementaux. Cette thèse, structurée en 3 volets, est ciblée sur l’étude de la famille NAC chez le blé tendre : les TaNAC. Dans un premier temps, nous avons étudié la structuration génomique et phylogénétique des 488 membres de la famille TaNAC, recensés à partir de la base de données la plus récente du blé tendre.Nous avons aussi étudié l’histoire évolutive de cette famille, qui a été marquée par des événements de duplication et de rétroposition. Enfin, une analyse de sa diversité allélique a permis d’identifier des gènes qui présentent des SNP montrant une forte association avec des paramètres d’accumulation des protéines de réserve dans le grain. Le deuxième chapitre de cette thèse a porté sur l’étude de l’expression de ces 488 gènes TaNAC dans plusieurs organes et en réponse aux stress thermique et sécheresse. Une analyse globale a été réalisée à partir de données bio-informatiques, suivie d’une étude in planta de l’expression d’une sélection de 23 gènes. Les profils d’expression obtenus ont révélé l’existence de 4 gènes TaNAC, encore jamais décrits dans la littérature et qui interviennent dans le développement du grain de blé tendre mais aussi dans sa réponse adaptative à plusieurs stress abiotiques. Le troisième volet de cette thèse a donc porté sur la caractérisation génétique, moléculaire et physiologique de ces 4 facteurs de transcription TaNAC. Ils appartiennent à un clade rassemblant des séquences présentant des similitudes génomique et structurale. De plus, ils sont localisés dans le noyau et leurs profils d’expression sont similaires, avec toutefois un niveau variable entre gènes et entre homéologues pour chaque gène. En réponse à un stress thermique modéré, ce profil d’expression est accéléré au cours du développement du grain ; le stade 120°Cj étant le stade clé qui montre la plus grande différence d’expression de ces gènes entre les conditions contrôle et stressée. Pour des raisons techniques, la production de plantes transgéniques sur- et sous-exprimant ces gènes n’a pas permis de valider l’implication de ces 4 TaNAC dans le développement du grain et en réponse à la température. Une analyse de génétique d’association a toutefois permis de mettre en évidence un lien entre des marqueurs moléculaires situés dans ces gènes et l’accumulation des protéines de réserve.Globalement, les résultats obtenus ont montré que des membres de la famille TaNAC sont impliqués dans le développement du blé tendre et dans sa réponse aux stress abiotiques. Plus particulièrement, 4 facteurs de transcription TaNAC semblent jouer un rôle clé dans l’accumulation des protéines dans le grain en réponse à un stress thermique modéréBread wheat, Triticum aestivum, is one of the most cultivated cereal in the world. The climate change that is currently developing strongly constrains crops and impairs their yield. Understanding the wheat response mechanisms to abiotic stresses is therefore a current issue. Several major families of transcription factors, including the NAC family, are involved in the plant development and its response to environmental stresses. This thesis, structured in three parts, is focused on the study of the NAC family in bread wheat (TaNAC).First, we studied the genomic and phylogenetic structure of the 488 members of the TaNAC family identified from the latest database of bread wheat. We also studied the evolutionary history of this family, which was marked by duplication and retroposition events. Finally, an analysis of its allelic diversity allows us to identify genes with SNP showing a strong association with storage protein accumulation parameters in the grain. In a second part, we studied the expression of these 488 TaNAC genes in several organs and in response to heat and drought. An overall analysis was performed using bioinformatic data, followed by an in planta study of the expression of a selection of 23 genes. The expression profiles revealed that four TaNAC genes, never described in the literature, are involved in the wheat grain development but also in its adaptive response to several abiotic stresses. In a third part, we focused on the genetic, molecular and physiological characterization of these four TaNAC transcription factors. They belong to a clade gathering sequences with genomic and structural similarities. Moreover, they are localized in the nucleus and their expression profiles are similar, with a variable level between genes and between homeologs for each gene. In response to moderate heat stress, this expression profile is accelerated during grain development and a key stage at 120°Cj was identified, it shows the greatest difference in genes expression level between control and stressed conditions. For technical reasons, the production of transgenic plants over- and under-expressing these genes did not validate the involvement of these 4 TaNAC in grain development and in its temperature response. An association genetic analysis, however, showed a link between molecular markers located in these genes and the storage proteins accumulation. Overall, the results showed that members of the TaNAC family are involved in the bread wheat development and its response to abiotic stresses. In particular, four TaNAC transcription factors appear to play a key role in grain protein accumulation in response to a moderate heat stress
11
Aeilts, Amber. "Reactions to receiving family health information via infographic video." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555065910789879.
12
Holbert, Joanne M. "The Relationship of Involvement in a Support Group, Communication Patterns, and Marital Satisfaction in Couples with a Genetic Mutation for Breast and Ovarian Cancer (BRCA)." University of Akron / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=akron1320248458.
13
Reilly, Drew D. "The Narratives of Young Women with BRCA 1/2 Gene Mutation: A Qualitative Analysis." ScholarWorks@UNO, 2014. http://scholarworks.uno.edu/td/1910.
Анотація:
A narrative qualitative research design was used to understand the stories of young women diagnosed with BRCA1 and BRCA 2 genetic mutation. Four participants were selected who met the following criteria: (a) the participant is diagnosed with BRCA1 or BRCA2 genetic mutation, b) is within the age range of 18 to 35, (c) is without a cancer diagnosis, and is (d) not currently pregnant and does not have children. The four participants were interviewed through open-ended inquiry. The participants’ narratives proved both similar and dissimilar. The themes were organized into within-case narratives and across-case narratives. The narratives revealed that young BRCA previvors face unique challenges and experiences, and many can be viewed from an underlying feminist lens. In response to the research questions, BRCA previvors revealed detailed narratives, explored issues of family planning, and explained the ways in which BRCA has changed their worldviews.
14
Bongard, Helene. "Mutationsanalyse eukaryoter Gene BRCA-Genomanalyse von 35 Familien mit Mamma- und-oder Ovarialkarzinomen mit vergleichenden Studien über unterschiedliche Analyseverfahren /." Wettenberg : VVB Laufersweiler, 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968401945.
15
Aducci, Christopher John. "Itti'at akka' wáyya'ahookya ikkobaffo (Trees bend, but don’t break): Chickasaw family stories of historical trauma and resilience across the generations." Diss., Kansas State University, 2013. http://hdl.handle.net/2097/15546.
Анотація:
Doctor of PhilosophyDepartment of Family Studies and Human Services
Joyce A. Baptist
The Chickasaw represent one non-reservation bound American Indian tribe whose experiences of family life, historical trauma and resilience has not been fully understood. Therefore, this study sought to identify the qualities common to Chickasaw families, Chickasaw families' experiences of historical trauma and the factors that contribute to Chickasaw families' ability to persevere under adversarial circumstances. Using in-depth phenomenological interviews with nine (N = 9) three-generation minimum Chickasaw families, four central themes emerged that answered the four research questions. The first theme, "Chokka-chaffa' Nanna Mó̲́đma Ímmayya/The Family Is Everything" indicated that Chickasaw families were a heterogeneously complex system with a natural orientation toward the family unit itself, whereby the families valued emotional closeness, warmth and affection, quality time together, praise, respect and openness. Families were involved with one another and were active participants in strengthening their own families and communities. Families were prideful of family members' accomplishments and valued extended kin and spirituality. Further, families were confronted with challenges, but showed an ability to "bend, but not break," often citing the very same qualities, such as involvement, pride and an orientation toward family, as contributing to their ability to solve problems and keep the family unit intact. The second theme, "Impalahá̲mmi Bíyyi'ka/They Have It Really Bad," indicated the families experienced historical trauma by mourning the loss of land, language, culture and identity and that losses went unacknowledged by their non-Native counterparts and were ongoing, thus expecting to affect younger and future generations. The third theme, "Chikashsha Poyacha Ilaa-áyya'shakatí̲'ma/We Are Chickasaw, and We Are Still Here" indicated that despite hardships, families saw resilience as a trait found within their Chickasaw heritage. Maintaining a positive outlook, a spirit of determination, a fierce loyalty toward family members and a close connection to the Chickasaw Nation further contributed to families' resilience. The fourth theme, "Hooittapila/They Help One Another" indicated that resilient qualities were passed in a multidirectional pattern throughout all generations of family members, whereby family members from all generations supported and uplifted one another. Also discussed are the study's strengths and limitations and the clinical and research implications for Chickasaw families.
16
Castro, Mayela. "Quality of Life in Female Breast Cancer Survivor in Panama." Scholar Commons, 2013. http://scholarcommons.usf.edu/etd/4651.
Анотація:
Abstract
Introduction: Breast cancer is the most common female cancer worldwide and it is also the principal cause of death from cancer among women globally. Breast cancer has the highest prevalence among Panamanian women and its incidence is also growing every year. Women living with and beyond breast cancer have special needs that have to be considered by society and the health care systems. After diagnosis, the quality of life (QOL) of women is highly affected, due to the emergence of physical, psychological and social effects which lead to changes in attitudes and expectations towards life.
Purpose: To evaluate the QOL, among Panamanian women who suffer from breast cancer, factors that could influence QOL and the main life areas where these women are more affected when they receive this diagnosis.
Methodology: A cross-sectional study was developed to measure the QOL of Panamanian breast cancer survivors in four domains (physical, social, psychological and environmental). A total of 240 survivor women completed 80% of the self-assessment QOL-BREF survey at the National Cancer Institute of Panama during March, 2013. Non-parametric statistical tests were used to define QOL based on the survey results, including sociodemographic and medical characteristics. A logistic regression model was performed to evaluate variables than can influence the quality of life among this population.
Results: Higher socioeconomic indicators as well as having greater levels of spiritual belief, younger age and less than 5 years of cancer diagnosis appear to produce positive and statistically significant differences in QOL among breast cancer survivors.
Conclusions: Breast cancer survivors in Panama have a good quality of life perception and are satisfied with their health. Support principally from family and friends plays a very important role in all aspects of QOL. Elderly women have different physical needs that could explain the lowest score reported in this study.
17
Abdollahian, Mehrnaz. "Estimating Likelihood of Having a BRCA Gene Mutation Based on Family History of Cancers and Recommending Optimized Cancer Preventive Actions." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5893.
Анотація:
BRCA1 and BRCA2 are gene mutations that drastically increase chances of developing breast and ovarian cancers, up to 20-fold, for women. A genetic blood test is used to detect BRCA mutations. Though these mutations occur in one of every 400 in the general population (excluding Ashkenazi Jewish ethnicity), they are present in most cases of hereditary breast and ovarian cancer patients. Hence, it is common practice for the physicians to require genetic testing for those that fit the rules as recommended by the National Cancer Comprehensive Network. However, data from the Myriad Laboratory, the only provider of the test until 2013, show that over 70 percent of those tested are negative for BRCA mutations [1]. As there are significant costs and psychological trauma associated with having to go through the test, there is a need for more comprehensive rules for determining who should be tested. Once the presence of BRCA is identified via testing, the next challenge for both mutation carriers and their physicians is to select the most appropriate types and timing of intervention actions. Organizations such as the American Cancer Society suggest drastic intervention actions such as prophylactic surgeries and intense breast screenings. These actions vary significantly in their cost, cancer incidence prevention ability, and can have major side effects potentially resulting in reproduction inability or death. Effectiveness of these intervention actions is also age dependent.
In this dissertation, both an analytical and an optimization framework are presented. The analytical framework uses supervised machine learning models on extended family history of cancers, and personal and medical information from a recent nationwide survey study of women who have been referred for genetic testing for the presence of a BRCA mutation. This framework provides the potential mutation carriers as well as their physician with an estimate of the likelihood of having the mutations. The optimization framework uses a Markov decision process (MDP) model to find cost-optimal and/or quality-adjusted life years (QALYs) optimal intervention strategies for those tested positive for a BRCA mutation. This framework uses a dynamic approach to address this problem. The decisions are made more robust by considering the variation in estimates of the transition probabilities by using a robust version of the MDP model.
This research study delivers an innovative decision support tool that enables physicians and genetic consultants predict the population at high risk of breast and ovarian cancers more accurately. For those identified with presence of the BRCA mutation, the decision support tool offers effective intervention strategies considering either minimizing cost or maximizing QALYs to prevent incidence of cancers.
18
Torres, Samuel Eliot. "The past and pending using cinema as a dialogue to break down walls in communication." Master's thesis, University of Central Florida, 2011. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5061.
Анотація:
The Past and Pending is a feature-length documentary by Samuel Eliot Torres, made as part of the requirements for earning a Master of Fine Arts in Film & Digital Media from the University of Central Florida. The film focuses on a family torn apart by a major decision to migrate to the U.S. from Puerto Rico. The protagonist, Torres, is now trying to receive closure from the events by asking the questions he could not ask as a child, but feels compelled to ask as an adult. Filming with only one person in the crew allowed for an intimacy and spontaneity that is prized by entrepreneurial digital cinema makers. Without the financial and scheduling constraints of enlisting a large crew, the film was allowed to thrive with a spontaneous and ongoing shooting schedule, controlled entirely by one person.ID: 029810413; System requirements: World Wide Web browser and PDF reader.; Mode of access: World Wide Web.; Thesis (M.F.A.)--University of Central Florida, 2011.; Includes bibliographical references (p. 17]).
M.F.A.
Masters
Film
Arts and Humanities
19
Suttman, Alexandra Grace. "Motivations for Males Affected by HBOC to Disclose Genetic Health Information to Family Members and Health Care Providers." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1459960861.
20
Bongard, Helene [Verfasser]. "Mutationsanalyse eukaryoter Gene : BRCA-Genomanalyse von 35 Familien mit Mamma- und-oder Ovarialkarzinomen mit vergleichenden Studien über unterschiedliche Analyseverfahren / eingereicht von Helene Bongard geb. Sormbroen." Wettenberg : VVB Laufersweiler, 2003. http://d-nb.info/968401945/34.
21
Amendola, Fernanda. "Qualidade de vida de cuidadores de pacientes com perdas funcionais e dependência atendidos em domicílio pelo programa de saúde da família do município de São Paulo." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/7/7137/tde-13072007-092505/.
Анотація:
Atualmente no Brasil, crescem em importância os estudos sobre cuidados domiciliários à saúde de pessoas com perdas funcionais e dependência e seus cuidadores, em razão das transições demográfica e epidemiológica do país. Na Atenção Básica, com a implementação do Programa Saúde da Família (PSF), o cadastramento das famílias feito pelos agentes comunitários de saúde tornou visíveis as necessidades de saúde desses pacientes, antes confinados a seus lares, e de seus cuidadores. Este estudo teve como objetivo avaliar a qualidade de vida de cuidadores familiares de pacientes com perdas funcionais e dependência, atendidos por equipes de saúde da família, relacionando-a a características sociodemográficas, condições de saúde, grau de sobrecarga percebida e o grau de independência funcional do paciente. Foram entrevistados 66 cuidadores familiares atendidos por equipes de PSF na região sul do município de São Paulo. Os instrumentos utilizados foram: 1) caracterização do cuidador familiar e do paciente; 2) WHOQOL-bref, para avaliação de qualidade de vida subjetiva; 3) Zarit Burden Interview (ZBI), para avaliação da sobrecarga do cuidador, e 4) Escala de Medida de Independência Funcional (MIF), para avaliação da capacidade funcional dos pacientes. Os cuidadores eram, em sua maioria, mulheres (83,3%), casadas (62,2%) com média de idade de 50,5 anos. Na condição de filhas ou filhos (37,9%) e esposas ou esposos (24,2%), cuidavam de pacientes com até 50% de dependência para atividades básicas da vida diária (MIF total = 57,82) e estavam moderadamente sobrecarregados (Zarit total = 32,12). Apresentaram melhor escore de qualidade de vida no domínio físico (66,72) e pior no domínio meio ambiente (52,51). A escala de sobrecarga, a presença de companheiro e a presença de doença no cuidador mostraram-se estatisticamente relacionadas à ´qualidade e vida geral´, no modelo de regressão múltipla final. Os resultados permitiram concluir que a qualidade de vida do cuidador correlacionou-se estatisticamente à sobrecarga percebida, indicando que quanto menores os escores em todos os domínios do WHOQOL-bref, maior a sobrecarga. Não houve associação estatística significativa entre o grau de independência funcional e a qualidade de vida do cuidador. Políticas públicas efetivas, destinadas a oferecer uma rede de serviços de suporte às famílias de pessoas com perdas funcionais e dependência, são primordiais para a diminuição da sobrecarga do cuidador e conseqüente melhora da sua qualidade de vida e de seus familiaresIn Brazil, the study of home health care of people with disabilities and dependency and their caregivers is growing in importance due to demographic and epidemiological changes in the country. With the introduction of the Family Health Program, the registration of families in Primary Care by community health agents brought to light the health needs of these patients, who were previously confined to their homes and to their caregivers. The objective of this study was to evaluate the quality of life of family caregivers of patients with disabilities and dependency, served by family healthcare teams, in terms of socio-demographic characteristics, health conditions, level of perceived burden and degree of functional independence of the patient. Family Health Care Program teams interviewed 66 family caregivers in the southern region of the city of São Paulo. The tools employed were: 1) characterization of the family caregiver and patient; 2) WHOQOL-bref, for the subjective evaluation of quality of life; 3) Zarit Burden Interview (ZBI), to evaluate caregiver burden, and 4) Functional Independence Measure Scale (FIM), to evaluate the functional capacity of patients. The caregivers were mostly women (83.3%), married (62.2%) with an average age of 50.5 years. Caregivers were daughters (37.9%) and spouses (24.2%), who cared for patients with up to 50% dependence for instrumental activities of daily living (MIF total = 57.82) and were moderately burdened (Zarit total = 32.12). The physical domain received the best quality of life score (66.72) and the worst score went to the environment domain (52.51). The amount of burden, presence of companion and presence of caregiver illness were statistically associated with general quality of life in the final multiple regression model. The results showed that caregiver quality of life is statistically correlated with perceived burden, indicating that the lower the score in all WHOQOL-bref domains, the higher the burden. No significant statistical association between degree of functional independence and caregiver quality of life was found. Effective public policies designed to offer a network of support services for families of people with dependence and functional loss are essential to reduce the burden placed on caregivers and consequently improve quality of life for them and their families
22
Mull, Haley Grace Liqing. "Break a Leg- Just not in Alabama: Analyzing the Timing of Medicaid's Adoption and State Variation in Medicaid Eligibility." Miami University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=miami1588084119596649.
23
West, Nicola. "Being a carrier and living with the BRCA gene mutation : an interpretive phenomenological study of the experiences of women who elect risk-reducing bilateral mastectomy, their husband's and family." Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/103512/.
Анотація:
Women who inherit the BRCA1/2 gene have up to an 85% lifetime chance of developing breast cancer and a 63% chance of developing ovarian Cancer. Since the publication and update of the UK Nice National Guidelines (2015) for women with a strong family history and Angelina Jolie, the famous American actress declared her status and her surgery, many more women are seeking testing in order to undergo bilateral risk-reducing mastectomy and oophorectomy. Very little is known about the longer-term effect on the woman her partner and her relatives following diagnosis and bilateral mastectomy from a qualitative research perspective. Aim - The aim of this study, therefore, was to explore, interpret and develop an understanding of the experiences of women and their relatives living with the BRCA gene who elect to have bilateral risk-reducing mastectomy in an attempt to improve clinical practice by providing a new horizon of understanding. Methods - An interpretive hermeneutic phenomenological study was conducted guided by the philosophy of Gadamer (2004) with its emphasis on a fused horizon of understanding with eight BRCA positive women, five of their husbands and five of their relatives. This study is a prospective study that took place in a large teaching hospital in Wales. Findings - This study provides a new fused horizon of understanding of what it means to be a BRCA Positive woman and a relative living with the BRCA gene who elect to undergo bilateral mastectomy as a risk-reducing modality. A hermeneutic text of interpretation exposed three main horizons (Gadamer, 2004). ‘The price of survival’, which includes the journey of the overall desire to survive, not just prevent cancer. ‘The altered child’s trajectory’ which involves the transference of the fear of cancer onto (for) children and future generations and ‘disembodied, a separation from self’ which includes the effects of surgery on sexuality, femininity and identity. These horizons unite the experiences of the women and her relatives resulting in a new fused horizon of understanding, ‘being disembodied’. These findings add knowledge and understanding for clinicians, researchers and policy makers working in the field of breast care with many implications for practice.
24
Villela, Berenice. ""Nudge a Mexican and She or He Will Break Out With a Story": Complicating Mexican Immigrant Masculinities through Counternarrative Storytelling." Scholarship @ Claremont, 2012. http://scholarship.claremont.edu/scripps_theses/98.
Анотація:
In this thesis, I explore Latino masculinities and contest their uniformity through transforming an oral history conducted with my father into a collection of short stories. Following storytelling traditions of Latino/Mexican culture, I converted an oral history interviews with my dad into a collection of short stories. From these short stories I extracted themes relating to the micro and macro manifestations of gender policing. Drawing from Judith Butler's Theory of performativity and Gloria Anzaldua's theory of Borderland identities, I rethink masculinity and offer Jose Esteban Munoz's theory of disidentification. With these theories in conversation, I analyze the themes of the short stories I present. In Chapter One, I investigate the potential of verguenza and respeto, or shame and respect, to complicate masculinity. In Chapter Two, I critically analyze my father's interaction with INS officials during his interview to become a U.S. resident. In these two sets of stories, I use disidentification to uncover the third space relationship with masculinity. I see this relationship at the intersections of race, class, gender and ability, the identities which come together to leave my father in the borderlands. Ultimately, I complicate masculinity through these analyses, offering a space for a nonoppressive masculinity.
25
Salazar, Tello Roxana Rocío. "Nivel de conocimiento sobre derechos en salud y su relación con el cumplimiento en la atención desde la perspectiva de los padres de pacientes hospitalizados en el Servicio de Cirugía General del Instituto Nacional de Salud del Niño- Breña 2017." Master's thesis, Universidad Nacional Mayor de San Marcos, 2019. https://hdl.handle.net/20.500.12672/10531.
Анотація:
Evalúa el nivel de conocimiento sobre derechos en salud y su relación con el cumplimiento en la atención desde la perspectiva de los padres de pacientes hospitalizados en el Servicio de Cirugía
General del Instituto Nacional de salud del Niño en el distrito de Breña – Perú, durante el período setiembre a diciembre 2017. El presente estudio es de tipo cualitativo, de diseño observacional correlacional de corte transversal, cuya muestra fue de 150 padres de pacientes atendidos en el Servicio de Hospitalización de Cirugía general. Los datos se obtuvieron a través de información sobre conocimiento sobre derechos en salud y percepción del cumplimiento de la atención. En la variable el nivel de conocimiento sobre derechos en salud prevaleció un nivel alto del 56% y en la variable cumplimiento en la atención prevaleció un nivel medio de 50.67%. La conclusión es que la mayoría de padres no conoce cuáles son sus deberes como usuarios de los servicios de salud.Tesis
26
Santana, dos santos Elizabeth. "Contribution of the Missense and Non-Coding BRCA1/2 Variants for the Hereditary Predisposition and Response to Treatment of Breast and Ovarian Cancers Assessment of the Functional Impact of Germline BRCA1/2 Variants Located in Non- Coding Regions in Families with Breast and/or Ovarian Cancer Predisposition Non-Coding Variants in BRCA1 and BRCA2 Genes: Potential Impact on Breast and Ovarian Cancer Predisposition." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASS027.
Анотація:
Les cancers de l'ovaire et du sein sont définis par les principales voies impliquées dans la tumorigénèse. Dans les cancers héréditaires du sein/ovaire (HBOC), les tumeurs présentant des variants pathogènes (PV) de BRCA1/2 présentent une altération de la réparation de l'ADN par recombinaison homologue (RH). Des années après la découverte des gènes BRCA1/2, les PV ont été uniquement recherchés sur l'ADN constitutionnel. Aujourd’hui, cette information est également recherchée au niveau tumoral car en plus de leur utilité pour améliorer le conseil génétique, elle est aussi impliquée dans le choix thérapeutique. Cependant, les données recueillies indiquent que les PV inactivant la protéine ne seraient pas l’unique mécanisme d’inactivation de la voie de réparation de l’ADN par RH. Dans ce contexte, l'objectif principal de cette thèse est d'identifier des mécanismes alternatifs d'inactivation de la voie HR pour améliorer à la fois: le conseil génétique et la prise en charge thérapeutique. À cette fin, nous avons tenté de contribuer à la classification de variants non-codants et faux-sens (autre que provoquant un stop prématuré) de BRCA1/2 et également recherché de nouveaux biomarqueurs de réponse thérapeutique dans d’autres gènes de la voie de HR.Nous avons décrit des variants constitutionnels dans des régions potentiellement importantes de régulation des gènes BRCA1 et BRCA2, et démontré qu'une partie d'entre eux étaient fonctionnellement actifs à mettre en lien avec la pathogénicité. Nous avons également exploré les caractéristiques moléculaires des tumeurs du sein et de l'ovaire des porteurs des variants BRCA1 et observé une prédominance de la perte de l'allèle sauvage pour les tumeurs des porteurs de variants pathogènes. Etant donné ces résultats, nous proposons d’intégrer les informations de LOH dans le modèle multifactoriel de classification des variants BRCA1. Enfin, nous avons mis en évidence des mécanismes alternatifs d'inactivation de la voie RH, dans une cohorte de patientes avec un cancer de l'ovaire présentant une excellente réponse aux platines, y compris des mutations constitutionnelles et somatiques des gènes BRCA1/2, l'hyperméthylation du promoteur BRCA1 ainsi que des mutations dans d'autres gènes de la voie RHOvarian and breast cancers are currently defined by the main pathways involved in the tumorigenesis. In hereditary breast/ovarian cancers (HBOC), tumors with BRCA1/2 pathogenic variants (PV) present an impairment of DNA repair by homologous recombination (HR). For many years, BRCA1/2 PV were only searched on germline DNA. Currently, this information is also searched at tumor level to personalize treatment. Even so, the reason of the inactivation of this pathway remains uncertain for most cases, even in the presence of HR deficient signature.Gathered evidence indicates that protein inactivating PV may not be the only mechanism of HR dysfunction. In this context, the main objective of this thesis is to identify alternative mechanisms of HR inactivation to improve both: genetic counseling and therapeutic response. For this purpose, we have attempted to contribute to non-coding and missense (other than premature stop codon) BRCA1/2 variant classification and searched for new biomarkers of therapeutic response to DNA damage agents in other HR genes.We identified germline variants in key transcriptional regulatory elements of BRCA1 and BRCA2, and demonstrated that part of them were functionally active and had additional arguments suggesting pathogenicity. We also explored molecular features of breast and ovarian tumors from BRCA1 variant carriers and observed a predominance of loss of the wild-type allele. Conforming to this evidence, we propose to incorporate LOH information, into the multifactorial model for BRCA1 variant classification. Finally, besides the enrichment of BRCA1/2 germline and somatic PV, we described alternative mechanisms of HR inactivation in a OC population presenting optimal response to platinum-based chemotherapy, including BRCA1 promoter hypermethylation and also mutations in other genes of HR pathway
27
Sohr, Martin. "Zabezpečovací systém pro rodinný dům." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219383.
Анотація:
Family house, security system, wireless communication, IQRF, RSA, central control unit, SPI, I2C, glass break sensors, motion sensors, magnetic contact sensors, graphic displey, LCD displey, microcontroler, SIM900, 24FJ256GB106, EA DOGM106, eDIPTFT43-A.
28
Scholl, Eva Elena. "Untersuchungen zur Informationsweitergabe in Familien mit erblichem Brust- und Eierstockkrebs." Doctoral thesis, 2021. https://doi.org/10.25972/OPUS-24325.
Анотація:
Für die hier beschriebene Studie wurde ein Fragebogen erstellt, welcher von 80 Trägerinnen und Trägern einer pathogenen Mutation in den Genen BRCA1 oder BRCA2 ausgefüllt wurde. Die Befragung sollte untersuchen, ob den Befragten das Risiko ihrer Verwandten, ebenso Mutationsträger zu sein, bewusst war. Weiterhin sollte ermittelt werden, ob sie die jeweiligen Risikopersonen darüber informierten. Es zeigte sich, dass den meisten Befragten dieses Risiko bekannt war. Einigen Personen schienen jedoch nicht genau zu wissen, welche Verwandten als „Risikopersonen“ zählen. Insbesondere war nicht allen Befragten die Möglichkeit bewusst, dass auch Männer die Mutation tragen und an ihre Kinder weitergeben sowie selbst an Brustkrebs erkranken können. Weiterhin gaben mehr als ein Viertel der Befragten an, dass sie mindestens ein Familienmitglied, obwohl es ihnen als Risikoperson bekannt war, nicht informierten. Als häufigste Grund hierfür wurde mangelnder Kontakt genannt. Vor dem Hintergrund der Angaben der Befragten sowie der aktuellen Forschungslage werden in der vorliegenden Arbeit Möglichkeiten diskutiert, wie die Anzahl der informierten Angehörigen verbessert werden könnteA questionnaire was sent to carriers of BRCA1/2 mutations to survey whether they knew about the risk of their relatives to be carriers as well and whether they informed those relatives about that risk. Among the 80 participants, most were aware of the risk of their relatives. However, the risk of male relatives to be mutation carriers seemed to have been undererstimated and more than one in four participants stated they did not inform every relative they knew to be at risk. The most frequently stated reason for not informing at-risk relatives was lack of contact
29
Lin, Yi-Jun, and 林怡君. "Do family firms help women break the glass ceiling?" Thesis, 2017. http://ndltd.ncl.edu.tw/handle/pm2bby.
Анотація:
碩士國立臺北科技大學
資訊與財金管理系碩士班
105
Using the listed firms in Shanghai and Shenzhen during the peiord 2004－2014, this study investigates whether family firms tend to appoint women to be exeucutives. We find that family firms appoint women to be executives more often than non-family firms do. The finding does not result form high percentage of women directors or the limited pool of talent in family firms. Compared to non-family firms, family firms are even more inclined to hire professional female CEOs. In the cultural environment of gender equality, family firms tend to appoint female CEOs. However, we also find that family firms of female CEO appointments exist glass cliff phenomenon, that is, familly firms tend to appoint female CEOs when their performance is poor or the risk is high.
30
Wang, Yung-Kai, and 王永凱. "Ovate Family Protein 1 as a Plant Ku70 Interacting Protein Involving in DNA Double-strand Break Repair." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/34580268935120116478.
31
Van, Breda Francois de Waal. "An investigation of selected factors influencing the success of small and medium-sized family businesses / Francois de Waal van Breda." Thesis, 2014. http://hdl.handle.net/10394/13999.
Анотація:
Family businesses have unique dynamics and success stories but at the same time
face unique challenges. Intergenerational small and medium-sized family businesses
in South Africa play an increasingly important role in creating jobs together with
wealth distribution. This study attempts to explore the complicated relationship and
inimitable characteristics of family business surroundings against the added
challenges of family business perceived success and family business continuity.
Notwithstanding family businesses being a prevalent phenomenon in the economies
of most countries, insight into this form of enterprise is still limited. Topics such as
commitment, entrepreneurial orientation, job satisfaction, satisfaction with life and
perceived success of the family business, among others, were investigated.
In order to achieve the primary objective of this study, a survey was undertaken using
a structured questionnaire. The reliability of the questionnaire was determined by
calculating the Cronbach alpha coefficient, which indicated that the questionnaire
used in this study conformed to the criteria of acceptable reliability and can be
regarded as internally consistent. The survey yielded 143 usable questionnaires from
42 family businesses restricted to Gauteng province and the North West province in
South Africa.
The nature of this study was investigative and descriptive statistics was therefore
used to analyse the statements of all the participating respondents. The selected
determinants influencing the perceived success of small and medium-sized family
business was then measured and regressional analyses were further conducted.
Conclusions were drawn from this study on the outcomes of the selected factors
influencing the perceived success of small and medium-sized family business.
Finally, a critical evaluation was done and practical recommendations are suggested
to improve family business wellness and, subsequently, increase the sustainability of
such business.MBA, North-West University, Potchefstroom Campus, 2015
32
Balážová, Anna. "Zobrazení rodiny v románech Intimacy (Hanif Kureishi), Scissors Paper Stone (Elizabeth Day)." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-323087.
Анотація:
This thesis concentrates on the depiction of family in two contemporary British novels. These are: Hanif Kureishiʼs In macy (1998), wri en in the first person narra ve, and Elizabeth Day's Scissors Paper Stone (2011), written in the third person narrative. This thesis analyses the novels from various perspectives with the main emphasis put on the theme of family. It also takes into consideration the different narrative modes used in the novels. In the theoretical part this thesis concentrates on the development of family with the main stress placed on the changes that took place in the second half of the twentieth century in Britain. The topics that it deals with are the breakdown of a relationship, fatherhood, dysfunctional communication and other themes concerning the family and interpersonal relationships.
33
Ang, Ee Kheng. "Career break or broken career? : mothers' experiences of returning to paid work : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at School of Sociology, Social Policy and Social Work, Massey University, Palmerston North, New Zealand." 2007. http://hdl.handle.net/10179/1671.
Анотація:
Servicemen returning from two World Wars were granted assistance in finding work, retraining and other benefits in recognition of the sacrifices they had made. Yet mothers' returning to work after time out bearing and raising children are reliant on a booming economy to obtain even limited entry to the labour market, and the work obtained is very often inferior to the jobs held by women before becoming mothers. Currently due to lower fertility rates and the ageing populations of the world's richer nations, a shortage of working-age people is predicted to continue into at least the middle of the twenty-first century. To overcome this shortfall, the Organisation for Economic Cooperation and Development (OECD) advises its member states to assist mothers to return to paid work sooner. Most OECD nations are complying, with varying degrees of success. Some policy frameworks make this goal more easily attainable than others. Mothers in liberal welfare states often return to paid work later than they might otherwise prefer. Many returners are overqualified for the work they are doing. While there appears to be relatively few barriers to re-entry, the choice of re-entry occupations are limited and returners are predominantly offered low status jobs with no career opportunities at the back of the job queue and gender queue. Mothers who interrupt their careers by taking a career break for childbearing and rearing generally face downward occupational mobility and loss of lifetime incomes. This thesis assesses the experiences of mothers who return to employment in one liberal nation, New Zealand. It applies Esping-Andersen's three models of welfare states and Reskin and Roos' gender queues model to the situation of returners. The study investigates the precise nature of the obstacles and processes encountered by a number of mothers attempting to resume a career. It argues that social policies matter: returners in countries where state intervention is more widespread and where there is universal, extensive and generous social provision and support for working mothers are economically better off. The research methods include in-depth interviews and a focus group with mothers, a mail questionnaire and interviews with employers, and a study of recent and current New Zealand and overseas government policies to assist working parents. The findings of this thesis are that regardless of skill levels, New Zealand returners are consigned to low status occupations where they are not fully integrated into the 'normal' full-time workforce with career opportunities. These mothers generally suffer more than one episode of returning to the back of the queue. They also earn less (weekly and annually) than mothers who do not take career breaks. The study identifies social policy frameworks and employers' policies and practices as factors contributing to the processes whereby returners are relegated to the back of the queue. Although New Zealand has recently brought in policies to assist mothers to return to paid work these initiatives have not addressed the processes that currently confine returners in low status, part-time employment. Policies similar to those created to specifically target the needs of ex-servicemen would go a long toward assisting mothers to access higher status and better-paid jobs at the head of the queue. The thesis concludes with policy recommendations to facilitate mothers' integration into such jobs.
34
Lowndes, Gillian Claire. "The need for a flexible and discretionary system of marital property distribution in the South African law of divorce." Diss., 2014. http://hdl.handle.net/10500/18819.
Анотація:
Substantive gender equality has yet to be achieved in South Africa. As such, when a decision is made for one of the spouses to a civil marriage to stay at home and care for the children born of the marriage, or make career sacrifices to care for children, that spouse is usually the wife. As a result, while the husband continues to amass wealth and grow his earning potential, the wife is unable to do so. In circumstances where such spouses are married out of community of property or subject to the accrual system with onerous exclusion clauses in the antenuptial contract, the wife may be left with little more than a claim for rehabilitative maintenance in the event of a divorce. The courts only have the discretion to make an equitable distribution of marital property in civil marriages with complete separation of property concluded prior to 1 November 1984 (or 2 December 1988) and customary marriages. It is arguable that this limitation of the judicial discretion violates the equality clause contained in the Constitution of the Republic of South Africa, 1996. A broad judicial discretion to equitably redistribute the spouses’ assets upon divorce is therefore proposed in this dissertation.Private Law
LL.M.