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Готові списки джерел за темами / Carbamylated darbepoetin

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Добірка наукової літератури з теми "Carbamylated darbepoetin"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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Статті в журналах з теми "Carbamylated darbepoetin"

1

Peresypkina, Anna A. "Correction of ischemic optic neuropathy in rats by carbamylated darbepoetin." Research Results in Pharmacology 4, no. 1 (2018): 43–50. http://dx.doi.org/10.3897/rrpharmacology.4.25262.

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Introduction: The protective effects of carbamylated darbepoetin on the model of ischemic optic neuropathy in rats were revealed. Objectives: To increase the effectiveness of pharmacological correction of experimental ischemic optic neuropathy in an experiment by using carbamylated darbepoetin. Methods: Measuring the microcirculation level in the retina of rats was carried out using laser Doppler flowmetry (LDF). Registration was done by the data acquisition system Biopac-systems MP-150 and AcqKnowledge 4.2 programme. For microscopy and morphometry, the prepared microslides were scanned using

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2

Peresypkina, Anna A. "Correction of ischemic optic neuropathy in rats by carbamylated darbepoetin." Research Results in Pharmacology 4, no. (1) (2018): 43–50. https://doi.org/10.3897/rrpharmacology.4.25262.

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Анотація:

Introduction: The protective effects of carbamylated darbepoetin on the model of ischemic optic neuropathy in rats were revealed. Objectives: To increase the effectiveness of pharmacological correction of experimental ischemic optic neuropathy in an experiment by using carbamylated darbepoetin. Methods: Measuring the microcirculation level in the retina of rats was carried out using laser Doppler flowmetry (LDF). Registration was done by the data acquisition system Biopac-systems MP-150 and AcqKnowledge 4.2 programme. For microscopy and morphometry, the prepared microslides were scanned using

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3

Elagin, V. V., D. A. Kostina, O. I. Bratchikov, M. V. Pokrovsky, and T. G. Pokrovskaya. "THE STUDY OF RENOPROTECTIVE PROPERTIES OF ERYTROPOETIN DERIVATIVES ON THE KIDNEY ISCHEMIA-REPERFUSION MODEL." Kuban Scientific Medical Bulletin 25, no. 6 (2018): 73–77. http://dx.doi.org/10.25207/1608-6228-2018-25-6-73-77.

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Aim.The research was designed to study the renoprotective properties of erythropoietin derivatives on the kidney ischemiareperfusion experimental model.Materials and methods.The renoprotective properties of asialo erythropoietin (0.4 μg/kg and 2.4 μg/kg 30 minutes before the induction of ischemia) and carbamylated darbepoetin (50 μg/kg 24 hours before the ischemic stimulus) were studied in comparison with erythropoietin and darbepoetin in a series of experiments on male Wistar rats on a 40-minute bilateral model of renal ischemia-reperfusion. The renoprotective properties were evaluated by the

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4

Pavel, D. Kolesnichenko* Alexander A. Dolzhikov Nina I. Zhernakova Andrey A. Shaposhnikov Alexander A. Stepchenko Galina A. Batischeva Konstantin M. Reznikov. "PRECLINICAL STUDY OF THE ALLERGENIC PROPERTIES OF CARBAMYLATED DARBEPOETIN." Indo American Journal of Pharmaceutical Sciences 04, no. 10 (2017): 3798–802. https://doi.org/10.5281/zenodo.1020044.

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The article presents the results of a study of allergenicity of a new drug from the group of erythropoietin, carbamylated darbepoetin. The study was performed according to the Russian manual of pre-clinical studies and carried out through the following tests: the reaction of active cutaneous anaphylaxis, systemic anaphylactic reaction and delayed type reaction. The results of the reaction of active cutaneous anaphylaxis showed that the drug had caused a stain at the injection site 2.87 ± 0.17 of size, not significantly differenced from the size of the stain caused by placebo solution — 2.74 ±

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5

Kostina, Darya A., Tatiana G. Pokrovskaya, and Vladimir Y. Poltev. "Renoprotective effect of carbamylated darbepoetin and udenafil in ischemia-reperfusion of rat kidney due to the effect of preconditioning and inhibition of nuclear factor kappa B." Research Results in Pharmacology 7, no. 1 (2021): 1–19. http://dx.doi.org/10.3897/rrpharmacology.7.63059.

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Анотація:

Introduction: Acute kidney injury is a widespread complication in hospitalized patients, with a high mortality rate and long-term complications affecting prognosis and quality of life and with high human and financial costs. In addition, to date, no clear algorithm for the prevention of this type of damage has been developed. Materials and methods: The research was carried out on male Wistar rats. A 40-minute renal ischemia-reperfusion model was used to model acute kidney injury. Further, the renoprotective properties of carbamylated darbepoetin, udenafil and their combination were assessed ba

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6

Kostina, Darya A., Tatiana G. Pokrovskaya, and Vladimir Y. Poltev. "Renoprotective effect of carbamylated darbepoetin and udenafil in ischemia-reperfusion of rat kidney due to the effect of preconditioning and inhibition of nuclear factor kappa B." Research Results in Pharmacology 7, no. (1) (2021): 1–19. https://doi.org/10.3897/rrpharmacology.7.63059.

Повний текст джерела

Анотація:

Introduction: Acute kidney injury is a widespread complication in hospitalized patients, with a high mortality rate and long-term complications affecting prognosis and quality of life and with high human and financial costs. In addition, to date, no clear algorithm for the prevention of this type of damage has been developed. Materials and methods: The research was carried out on male Wistar rats. A 40-minute renal ischemia-reperfusion model was used to model acute kidney injury. Further, the renoprotective properties of carbamylated darbepoetin, udenafil and their combination were assessed ba

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7

Gubareva, Victoria O., Anton L. Pazhinsky, Sergey S. Lugovskoy, et al. "Pharmacological correction of morphofunctional retinal injury using 11-amino acid fragment of darbepoetin in the experiment." Research Results in Pharmacology 5, no. 3 (2019): 43–55. http://dx.doi.org/10.3897/rrpharmacology.5.38730.

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Анотація:

Introduction: The retinoprotective effect of the 11-amino acid fragment of darbepoetin PRK-002 on the models of hypertensive retinal angiopathy and hypertensive neuroretinopathy in Wistar rats was investigated in comparison with carbamylated darbepoetin and sulodexide. Materials and methods: The protective effects of the pharmacological agents were assessed using the following criteria: a semi-quantitative assessment of changes in the eye fundus when performing ophthalmoscopy, the retinal blood flow, the b/a coefficient, eNOs expression in retinal vessels, specific number of neuronal nuclei in

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8

Gubareva, Victoria O., Anton L. Pazhinsky, Sergey S. Lugovskoy, et al. "Pharmacological correction of morphofunctional retinal injury using 11-amino acid fragment of darbepoetin in the experiment." Research Results in Pharmacology 5, no. (3) (2019): 43–55. https://doi.org/10.3897/rrpharmacology.5.38730.

Повний текст джерела

Анотація:

Introduction: The retinoprotective effect of the 11-amino acid fragment of darbepoetin PRK-002 on the models of hypertensive retinal angiopathy and hypertensive neuroretinopathy in Wistar rats was investigated in comparison with carbamylated darbepoetin and sulodexide. Materials and methods: The protective effects of the pharmacological agents were assessed using the following criteria: a semi-quantitative assessment of changes in the eye fundus when performing ophthalmoscopy, the retinal blood flow, the b/a coefficient, eNOs expression in retinal vessels, specific number of neuronal nuclei in

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9

Zhuchenko, M. A., M. V. Serebryakova, Yu A. Seregin, et al. "Carbamylated Darbepoetin Alfa: Structure and Properties." Biotekhnologiya 33, no. 4 (2017): 28–43. http://dx.doi.org/10.21519/0234-2758-2017-33-4-28-43.

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10

Kolesnichenko, P. D., O. S. Gudyrev, V. O. Soldatov, et al. "EVALUATION OF THE CARBAMYLATED DARBEPOETIN ACUTE TOXICITY." Современные проблемы науки и образования (Modern Problems of Science and Education), no. 6 2019 (2019): 127. http://dx.doi.org/10.17513/spno.29400.

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