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1

Wright, Rosemary Jean. "Applied epidemiology of communicable and non-communicable diseases, Victoria, 2016–2017." Master's thesis, Canberra, ACT : The Australian National University, 2018. http://hdl.handle.net/1885/154287.

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Анотація:
In this thesis, I present the projects and activities I have undertaken as a Master of Philosophy in Applied Epidemiology (MAE) Scholar in Victoria between February 2016 and November 2017. I was placed with the Environmental and Genetic Epidemiology Research Group at the Murdoch Childrens Research Institute (MCRI), and the Communicable Disease Epidemiology and Surveillance Unit at the Victorian Department of Health and Human Services (DHHS). At MCRI I worked on the Barwon Infant Study, a birth cohort study designed to investigate how early life environment can influence the development of immu
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2

Chochó, Karen S. "Hispanic migrants and cross-border disease control of Arizona's vaccine preventable diseases." restricted, 2008. http://etd.gsu.edu/theses/available/etd-04222008-151047/.

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Анотація:
Thesis (M.Ph.)--Georgia State University, 2008.<br>Title from file title page. Richard Rothenberg, committee chair; Russ Toal, Karen E. Gieseker, committee members. Electronic text (135 p. : col. ill.) : digital, PDF file. Description based on contents viewed August 12, 2008. Includes bibliographical references (p. 127-135).
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3

Cheung, Ka-nang Benny. "Hospital for infectious diseases." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25950927.

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4

Lee, Shiu-hung, and 李紹鴻. "Epidemiological surveillance of communicable diseases in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1991. http://hub.hku.hk/bib/B31981458.

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5

St, George Siobhan Clare. "Applied Epidemiology in Communicable Diseases, Victoria, 2016 - 2017." Master's thesis, Canberra, ACT : The Australian National University, 2018. http://hdl.handle.net/1885/154282.

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Анотація:
This thesis presents the projects and activities I have undertaken throughout 2016-2017 to fulfil the requirements of the Master of Philosophy - Applied Epidemiology (MAE). My placement was shared between OzFoodNet Victoria (within the Victorian Department of Health and Human Services) and the Microbiological Diagnostic Unit Public Health Laboratory (MDU). This shared placement provided me with the unique opportunity to experience the different day-to-day workings of a state health department and a public health reference laboratory, while also experienc
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6

Pressley, Meagan E. "Infectious Disease Models for the Zebrafish." Fogler Library, University of Maine, 2004. http://www.library.umaine.edu/theses/pdf/PressleyME2004.pdf.

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7

Chen, Qizhi. "Analysis of infectious disease data /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21841627.

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8

Ben, Aissa Soler Alejandra. "Rapid diagnostic test for the detection of communicable diseases." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2020. http://hdl.handle.net/10803/670392.

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Анотація:
La prevenció i el control de les malalties transmissibles depenen, en gran mesura, de la detecció ràpida i eficaç. Els mètodes convencionals per a la detecció d'un patogen, com ara el cultiu microbiològic, generalment requereixen molt de temps, són laboriosos, necessiten personal qualificat i no són aptes com a eines de diagnòstic en el punt d'atenció. El desenvolupament de mètodes de diagnòstic ràpid en el marc dels criteris ASSURED, de l'anglès (A) Affordable, (SS) Sensitive i Didàctiques, (O) User-friendly, (R) Rapid and Robust, (I) Equipment free, and (d) Deliverable to those who need i
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9

Tang, Shenglan, John Ehiri, and Qian Long. "China's biggest, most neglected health challenge: non-communicable diseases." BioMed Central, 2013. http://hdl.handle.net/10150/610162.

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Анотація:
BACKGROUND:Over the past two decades, international health policies focusing on the fight against the human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), tuberculosis (TB), malaria, and those diseases that address maternal and child health problems, among others, have skewed disease control priorities in China and other Asian countries. Although these are important health problems, an epidemic of chronic, non-communicable diseases (NCDs) in China has accounted for a much greater burden of disease due to the ongoing rapid socioeconomic and demographic transition.DISCUSSI
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10

Zulu, Tryphine. "Socioeconomic inequalities in non-communicable diseases in South Africa." Doctoral thesis, Faculty of Health Sciences, 2019. https://hdl.handle.net/11427/31799.

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Анотація:
Non-communicable diseases (NCDs) have reached epidemic proportions globally and in South Africa. This thesis is situated within the health equity framework. The aim is to assess the extent of wealth related inequalities in NCDs and to assess the impact of the social determinants of health in mediating these inequalities. Data from the first South African National Health and Examination Survey (SANHANES-1) and wave 4 of the South African National Income Dynamics Study (NIDS) were used. The methods used include the concentration curve, concentration index and decomposition analysis to assess the
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11

Blight, Joshua. "Intervention methods against mosquito-borne diseases." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:45f39b22-5393-4d29-afe1-580c16d530d6.

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Анотація:
Mosquito-borne diseases account for hundreds of thousands of deaths each year, highlighting the need for successful intervention methods, which can be targeted at either the pathogen, mosquito vector, or human host. This thesis aims to contribute to better intervention methods focused against malaria and dengue by either (i) improving available research tools, (ii) enhancing the understanding of a promising intervention method or (iii) designing new intervention candidates. Firstly, a superior method for studying in vitro malaria infection of the liver is shown, with implications for vaccine a
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12

Murphy, Georgina Anne Veronica. "Chronic non-communicable diseases and risk factors in rural Uganda." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707995.

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13

GUERRA, FEDERICA. "PSYCHOSOMATIC INSIGHTS IN HEALTH MANAGEMENT OF CHRONIC NON-COMMUNICABLE DISEASES." Doctoral thesis, Università degli Studi dell'Aquila, 2022. https://hdl.handle.net/11697/198075.

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Анотація:
The thesis is based on studies performed at Department of Medicine and Public Health during XXXIV doctoral course, curriculum “Epidemiology, preventive, rehabilitative and occupational medicine’ (Coordinator Prof. Claudio Ferri) from 2018-2021, under supervision Prof. Domenico Passafiume and, Prof. Dina Di Giacomo. Doctoral Programme expected learning of the experimental techniques and methodologies of scientific research, through access to different types of patients by age, clinical pathology, psychopathology and, need for intervention. Doctoral Course was divided in two dimensions: a) Clini
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14

Kwok, Kin-on. "Models of directly transmitted respiratory pathogens in hospitals and households." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B40687557.

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15

Nakayasu, Ernesto Satoshi. "Molecular characterization of Trypanosoma cruzi and shed vesicle components involved in host immunomodulation and cell invasion." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2008. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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16

Elwell-Sutton, Timothy Mark. "Inequality, inequity and the rise of non-communicable disease inChina." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B5016272X.

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Анотація:
Background: Rapid economic growth in mainland China has been accompanied in recent years by rising levels of inequality and a growing burden of non-communicable disease (NCD), though little is known at present about the relations between these forces. This thesis makes use of data from a large sample of older men and women in Guangzhou, one of China’s most developed cities, to examine the relations between inequality, inequity and non-communicable disease. Objectives: This thesis addresses two research questions: what is the relationship between inequality/inequity and non-communicable dise
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17

Reddiar, Dona. "Regulatory B and T cells in Helicobacter pylori infection." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/51220/.

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Анотація:
In the human gastric mucosa, an inflammatory response stimulated by H. pylori infection can lead to gastric cancer and peptic ulcer disease. Expression of the i1 active variant of Vacuolating Cytotoxin A (VacA) by the colonising bacterial strain has been identified as an independent risk factor for disease. VacA skews the adaptive immune response towards a regulatory phenotype to promote persistent H. pylori colonisation. In H. pylori-infected individuals, regulatory T cells (Tregs), which suppress inflammation through mechanisms including interleukin-10 (IL-10) production, are thought to play
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18

Pinder, Leila. "An international study of the use of pandemic vaccines during the 2009-10 influenza A(H1N1) pandemic : a qualitative methodological study." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/40590/.

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Анотація:
Background: The 2009-10 influenza A(H1N1) pandemic was the first pandemic influenza of the twenty-first century and presented the first major opportunity for the use of influenza vaccines en-masse during a pandemic scenario. National anticipatory policies of pandemic influenza vaccine preparedness were implemented, and vaccine guarantee agreements were activated. Large quantities of vaccines were purchased and made available to identified citizens over the course of the pandemic. The use of pandemic influenza vaccines has been examined in this research. Methods: A comparative health policy app
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19

Thompson, Brett Morinaga Mikler Armin. "Development, implementation, and analysis of a contact model for an infectious disease." [Denton, Tex.] : University of North Texas, 2009. http://digital.library.unt.edu/permalink/meta-dc-9824.

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20

Morandi, Elena. "The viral hypothesis in multiple sclerosis : role of Epstein-Barr virus and human endogenous retroviruses." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/45125/.

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Epstein Barr Virus (EBV) is a major risk factor in Multiple Sclerosis (MS), via as yet unclear mechanisms. Several hypotheses have been proposed to explain how EBV infection could cause MS and the aim of this thesis was to better understand the mechanisms of action of EBV in the context of MS studying a) the role of EBV in myelin antigen presentation by B cells and b) the association of HERVs with MS. In a non-human primate experimental autoimmune encephalomyelitis (EAE) model, an EBV-related lymphocryptovirus enables B cells to protect a proteolysis-sensitive immunodominant myelin oligodendro
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21

Daniel, Priya. "A study on epidemiological trends in community acquired pneumonia and associated outcomes in the UK." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/46813/.

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Background Community acquired pneumonia (CAP) is a common illness in patients admitted to hospital, accounting for nearly 10% of acute medical admissions. Despite widespread use of antimicrobial therapy, morbidity and mortality from this disease remains high. In recent years in the UK, there have been significant developments in both preventative and treatment strategies for this illness. To understand the impact of these changes and direct future management strategies, it is important that the epidemiology of this disease is fully understood. This thesis investigates changes in epidemiology a
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22

Elimian, Osezele Kelly. "Evaluation of early diagnostic approaches for malaria and pneumonia in children under-five presenting at the primary healthcare level in Benin City, Nigeria : a mixed methods study." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/48409/.

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Анотація:
Background Malaria and pneumonia are the leading causes of under-five mortality in sub-Saharan Africa especially in Nigeria. The Integrated Management of Childhood Illness (IMCI) guidelines were developed by the World Health Organisation (WHO)/United Nations Children’s Fund (UNICEF) as a strategy to reduce the burden of these and other preventable childhood diseases. However, there appears to be a paucity of evidence on the diagnostic performance of the revised IMCI guidelines and whether they offer an advantage over lay diagnosis (caregiver) for malaria and pneumonia management in Nigeria. Ai
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23

Gutierrez, Louis Michael. "Agent-based simulation of disease spread aboard ship." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2005. http://library.nps.navy.mil/uhtbin/hyperion/05Mar%5FGutierrez.pdf.

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Анотація:
Thesis (M.S. in Modeling, Virtual Environments and Simulations (MOVES))--Naval Postgraduate School, March 2005.<br>Thesis Advisor(s): Chris Darken. Includes bibliographical references (p. 47-48). Also available online.
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24

Intrusi, Valentina. "Managing Challenges of Non Communicable Diseases during Pregnancy: An Innovative Approach." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/15675/.

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Анотація:
Le sfide lanciate dalle malattie non trasmissibili sono accolte da tecnologie sempre più all'avanguardia. Nonostante questo, ancora oggi gestire e monitorare gravidanze a rischio rimane un problema. La simulazione di condizioni come quella data dal diabete gestazionale, può aiutare a capire quali sono i principali fattori che influenzano l'andamento della malattia in modo da poterne evitare l'insorgenza e, in questo modo, migliorare la salute di madri e generazioni future. Questa tesi ha come obietto lo studio e il miglioramento di un sistema Agent-Based pensato per il trattamento del diabete
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25

Reames, Steve. "Detecting the Presence of Disease by Unifying Two Methods of Remote Sensing." Thesis, University of North Texas, 2002. https://digital.library.unt.edu/ark:/67531/metadc3120/.

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There is currently no effective tool available to quickly and economically measure a change in landmass in the setting of biomedical professionals and environmental specialists. The purpose of this study is to structure and demonstrate a statistical change-detection method using remotely sensed data that can detect the presence of an infectious land borne disease. Data sources included the Texas Department of Health database, which provided the types of infectious land borne diseases and indicated the geographical area to study. Methods of data collection included the gathering of images produ
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26

Hussein, Nawfal Rasheed. "The pathogenesis of Helicobacter pylori associated diseases in Kurdistan region, Iraq." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/10782/.

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Helicobacter pylori is regarded as the most important risk factor for peptic ulcer disease and gastric cancer. In Kurdistan region, northern Iraq, gastric cancer is rare (5/100,000). To investigate some possible reasons for this, the prevalence of H. pylori infection, gastric mucosal histopathological changes in H. pylori infected subjects, and virulence factor genotypes (especially dupA) of colonising strains were studied. The immune response to H. pylori infection, focusing on genes associated with T-helper (Th) and regulatory T-cell (Treg) cells, was also investigated. It was found that 79%
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27

Flohr, Carsten. "Helminths and allergic disease in Vietnam." Thesis, University of Nottingham, 2007. http://eprints.nottingham.ac.uk/10408/.

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Background: Allergic disease is uncommon in developing countries, especially in rural areas. A protective effect of helminth infection has been implicated as a potential explanation. Objectives: To determine whether reduced exposure to helminth infection is associated with a higher risk of allergen skin sensitisation and allergic disease, and whether such an association could be explained by a helminth-induced up-regulation of certain cytokines, in particular anti-inflammatory IL-10. Methods: We invited 1,742 rural Vietnamese schoolchildren to take part in a cross-sectional baseline survey fol
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28

Olfat, Farzad. "Helicobacter pylori : bacterial adhesion and host response." Doctoral thesis, Umeå universitet, Odontologi, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-133.

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Анотація:
The gastric pathogen Helicobacter pylori infects more than half of the population worldwide. H. pylori manage to establish persistent infection, which would be life-long if not treated. In order to establish such an infection, this pathogen has to deal with the host immune system. H. pylori has certain characteristics which make the bacteria less announced to the host immune system. Additionally, for remaining in the harsh and acidic environment of the stomach with peristaltic movements and a high frequency of turnover of epithelial cells, H. pylori has developed different binding modes to str
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29

Wen, Allisandra. "Global interaction patterns and disease transmission a case study of China /." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43786005.

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30

Hale, Rachel. "An actor-network analysis of the healthcare worker influenza immunisation programme in Wales, 2009-2011." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/33126/.

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Анотація:
Frontline healthcare workers (HCWs) in the UK have been prioritised for free occupational immunisation against seasonal influenza since 1999. During the 2009-10 influenza pandemic, they were identified as a priority group to receive the strain-specific vaccine. Nevertheless, take-up rates among HCWs have rarely exceeded 50%, even during the pandemic. Most attempts to change this situation have been predicated on the assumption that these low rates are the result of reluctance or resistance by individual HCWs, who must be persuaded or coerced to comply with employer directives. To gain a novel
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31

Bewick, Thomas. "Improving outcomes in patients with community-acquired pneumonia." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12432/.

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Анотація:
Community-acquired pneumonia (CAP) is a leading cause of adult morbidity and mortality worldwide despite decades of effective antibiotics and vaccination initiatives. There have been no recent significant improvements in outcomes, including 30-day mortality. The bacterium Streptococcus pneumoniae is the most prevalent causative pathogen in CAP, being found in up to half of cases. In September 2006 a childhood pneumococcal vaccine (PCV-7) was introduced, leading to reductions in vaccine-type (VT) pneumococcal disease in infants, with possible additional benefits reported in adults. However, the
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32

Lawson, Adam. "A study of the natural history of hepatitis C infection within a geographically determined population (Trent HCV study)." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12477/.

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Анотація:
The epidemiology and natural history of Hepatitis C has been studied in a large geographically determined population (Trent HCV study). It has previously been suggested that patients with Hepatitis C and a persistently normal Alanine aminotransferase (PNALT) represent a group of patients with mild disease and at low risk of disease progression. Patients with PNALT were, therefore, compared to those with an elevated ALT. The majority of patients initially fulfilling the definition of a PNALT had an abnormal ALT within 3 years of follow-up. They also demonstrated similar rates of fibrosis progre
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33

Killingley, Ben. "Investigations into human influenza transmission." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/13364/.

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Анотація:
Limited understanding of influenza transmission has been a frequent obstacle during the development of pandemic influenza infection prevention and mitigation strategies. The science is hotly debated, especially the relative importance of transmission via large droplets or aerosols. Clarification of the relative importance of different modes of transmission is critical for the refinement of evidence-based infection control advice and has been called for by the European Center for Disease Control (ECDC), the World Health Organization (WHO), and the US Institute of Medicine. The primary aims of t
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34

Stanczyk, Nina M. "An investigation of DEET-insensitivity in Aedes aegypti." Thesis, University of Nottingham, 2011. http://eprints.nottingham.ac.uk/11828/.

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N,N-Diethyl-m-toluamide (DEET) is one of the most effective and commonly used mosquito repellents. However, during laboratory trials a small proportion of mosquitoes are still attracted by human odours despite the presence of DEET. In this study behavioural assays identified Aedes aegypti females that were insensitive to DEET. The selection of either sensitive or insensitive groups of females with males of unknown sensitivity over several generations resulted in two populations with different proportions of insensitive females. Crossing experiments showed the ‘DEET-insensitivity’ trait to be d
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35

Roy, Anupama. "Mobile game based learning for 'Males having Sex with Males' peer educators in India." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/28292/.

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Анотація:
This thesis aims to examine the effectiveness of a mobile phone based SMS game as a learning intervention for the Peer Educators of the Males having Sex with Males (MSM) groups in Kolkata, India. MSM groups are marginalised and are at higher risk of HIV/AIDS, falling under the core groups for the National AIDS Control and Prevention programmes in India. Peer to peer education for behaviour change in HIV/AIDS prevention projects is a bottom up approach to reach out to this marginalised population for HIV prevention. Training is in place for MSM peer educators but research shows gaps in their su
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36

Baloch, Baby Kanwal. "Development of a targeted drug delivery system for the treatment of hepatitis C virus infection." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/14295/.

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Анотація:
Background: Hepatitis C virus infection affects more than 170 million people worldwide and is frequently associated with chronic liver disease and hepatocellular carcinoma. No protective vaccine is yet available and the current standard of care, consisting of pegylated interferon alpha and ribavirin, has limited efficacy. Ribavirin is a key component of any effective anti-HCV regimen. However, accumulation of ribavirin in the red cell compartment not only reduces drug efficacy as a result of diversion to extra-hepatic sites but also produces haemolytic anaemia which can lead to dose reduction
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37

Myles, Puja Runa. "A study of the impact of statins, ACE inhibitors and gastric acid suppressants on pneumonia risk and mortality using the Health Improvement Network Database." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/10957/.

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Анотація:
Pneumonia is a common diagnosis in general practice and is associated with significant morbidity and mortality. Current estimates of pneumonia incidence in the UK are based on studies more than a decade ago and little is known about longer term outcomes in pneumonia patients. Though much is known about the aetiology of pneumonia and predictors of mortality, an emerging area for research is the relationship between commonly prescribed drugs in general practice and pneumonia. The aims of this thesis were first, to determine overall incidence and mortality for pneumonia and how these vary by soci
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38

Matar, Suzan. "Characterization of staphylococcal small colony variants and their pathogenic role in biomaterial-related infections with special reference to Staphylococcus epidermidis." Thesis, University of Nottingham, 2004. http://eprints.nottingham.ac.uk/12135/.

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Анотація:
There are many surgical implanted devices in current use and all are prone to biomaterial-related infections (BRI) associated with staphylococcal biofilm formation. BRI are usually associated with S. epidermidis or S. Aureus and are characterized by treatment failure and chronicity resulting in reoperation, removal of the implant, and loss of function or death. Staphylococcal small colony variants (SCVs) may be generated by exposure to sublethal concentrations of antibiotics or nutrient limitation which may occur in biofilms. Although the characteristics of S. aureus SCVs have been well studie
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39

Cortes, Rojas Aaron. "Psychoneuroimmunology : a cross-cultural, biopsychosocial study of the role of perceived social support for people living with HIV/AIDS." Thesis, University of Nottingham, 2011. http://eprints.nottingham.ac.uk/11829/.

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Анотація:
Background: The immunological as well as the psycho-social impact, of living with HIV/AIDS transform HIV/AIDS into a multidimensional process. Stigma and discrimination against people living with HIV/AIDS (PLWHA) are proposed as hostile scenarios increasing hopelessness and reducing perceived and real social support affecting people’s health status. Peer support strategies are proposed as key factors for dealing with this scenario; additionally, socio-cultural variables may determine the provision and perception of social support. Objectives: To enhance the understanding of the process of livi
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40

Nalubega, Sylivia. "Care in HIV drug trial closure : perspectives of research participants and staff in Uganda." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43339/.

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Background: After three decades, Human Immunodeficiency Virus (HIV) continues to pose significant threats globally. The efforts to curb the HIV epidemic have required investment in research, with clinical trials being a major focus, to develop HIV prevention, treatment, and cure interventions. A large portion of such research has been undertaken within low income settings, due to the high burden of HIV and the availability of willing volunteers within this setting. HIV research calls for the implementation of ethical research practice which is informed by policy guidelines. However, current po
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41

White, Jonathan Richard. "Developing new predictors of Helicobacter pylori associated disease and its progression." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/42983/.

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Since discovery H. pylori has been one of the most intensively researched bacteria. Although the majority of those infected remain asymptomatic it can lead to serious diseases which carry significant morbidity and mortality. The most serious complication of H. pylori infection is gastric cancer and one of the most effective ways to reduce the associated mortality is to detect pre-malignant disease, as this develops in a step wise manner. Using advanced endoscopy is one way to detect pre-malignant conditions but due to the variety in endoscopic techniques and mucosal classifications the diagnos
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42

Hamed, Mohamed R. "Immune responses to hepatitis C virus (HCV) : investigation of the role of L-ficolin and anti-E1E2." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/31183/.

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Hepatitis C virus (HCV) causes acute and chronic liver diseases in humans. Its two envelope proteins, E1 and E2, are heavily glycosylated. They interact with host cell receptors and provide a target for host immune recognition. The host virus interactions determine the pathogenesis and outcome of HCV infection. L-ficolin is a soluble pattern recognition molecule of importance in innate immune defence against microorganisms. It activates the lectin complement pathway upon binding to carbohydrate recognition patterns on microorganisms. It was hypothesised that L-ficolin could interact with HCV g
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43

Mwalabu, Gertrude Grey Tiwonge. "Telling their story : perspectives of young women, their caregivers and service providers regarding the experiences of growing up with perinatally-acquired HIV in Malawi." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/14506/.

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Background: Globally, the number of adolescents living with perinatally-acquired HIV continues to rise including in Malawi. To date, this group has received relatively less attention in the field of HIV care; yet they are increasingly surviving into adulthood. There is a growing need for the development of appropriate care and support services for this group; however their sexual and reproductive health (SRH) needs remain poorly addressed. Research Aim: This study aimed to explore perinatally-infected young women’s experiences of growing up with HIV in order to understand their SRH outcomes wi
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44

Ndirangu, Eunice Wambui. "Communication and interaction in the context of routine provider initiated HIV testing and counselling for HIV : the case of Kenya." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/38061/.

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Background: The global policy focus of today’s HIV efforts and strategies is to reverse the spread of HIV/AIDS and provide care, treatment and support. A key component of this strategy is to increase individual HIV status awareness through expansion of HIV testing and counselling (HTC). However, the numbers tested still remain low and evidence suggests that there are significant missed opportunities for HIV testing in clinical settings. One key strategy to expand HTC in clinical settings has been to implement a policy of ‘provider initiated counselling and testing’ (PITC) in which all patients
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45

Chua, Ser Ling. "Papular pruritic eruption of human immunodeficiency virus infection." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/30750/.

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Background Papular pruritic eruption (PPE) of human immunodeficiency virus (HIV) infection is common HIV-infected populations who live in tropical and subtropical regions. It is characterized by chronic and intensely itchy papules that are usually more highly concentrated on the extremities, adversely impacting on quality of life. Its aetiology has been postulated to be an altered and exaggerated immunological response to insect bites or stings. It has been reported to diminish in severity or resolve with antiretroviral therapy (ART). Its presence after at least six months of ART has been prop
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46

O'Neill, Martin Joseph Mikler Armin. "Computational epidemiology analyzing exposure risk : a deterministic, agent-based approach /." [Denton, Tex.] : University of North Texas, 2009. http://digital.library.unt.edu/permalink/meta-dc-11017.

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47

Liew, F. Y. "Cell mediated-immunity against infectious diseases." Thesis, Canberra, ACT : The Australian National University, 1990. http://hdl.handle.net/1885/142999.

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48

Leung, Yiu-hong. "Evaluation of the sentinel surveillance system on communicable diseases in Hong Kong." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/b39724207.

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49

Leung, Yiu-hong, and 梁耀康. "Evaluation of the sentinel surveillance system on communicable diseases in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B39724207.

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50

Pastakia, Sonak D. "Developing self-sustainable models of care for non-communicable diseases in Kenya." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/91742/.

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Background (Kenya) Sub-Saharan Africa (SSA) is in the midst of experiencing an unprecedented increase in non-communicable diseases (NCD), specifically diabetes and hypertension. This shift has required public sector health systems, which have historically focused on managing acute diseases, to redesign their services to appropriately serve chronic disease needs. Issue Addressed In order to provide a description of our efforts to bring up comprehensive services for NCDs in rural Kenya within this thesis, I have specifically selected publications which target different aspects of the healthcare
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