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1

Dr.K.Lenin. "CONDITION OF SUBSTANCE SEARCH ALGORITHM FOR SOLVING REACTIVE POWER PROBLEM." International Journal of Research - Granthaalayah 5, no. 9 (2017): 230–43. https://doi.org/10.5281/zenodo.1002721.

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Анотація:
In this paper, Condition of Substance Search (COS) algorithm is introduced to solve optimal reactive power dispatch problem. The Condition of Substance Search (COS) algorithm is based on the simulation of the shape of substance incidence. In Condition of Substance Search (COS) algorithm, individuals follow molecules which interrelate to each other by using evolutionary operations which are based on the corporal principles of the thermal-energy motion mechanism. The algorithm is developed by considering each condition of substance in harmony with different exploration–exploitation ratio. The ev
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2

Lenin, K. "CONDITION OF SUBSTANCE SEARCH ALGORITHM FOR SOLVING REACTIVE POWER PROBLEM." International Journal of Research -GRANTHAALAYAH 5, no. 9 (2017): 230–45. http://dx.doi.org/10.29121/granthaalayah.v5.i9.2017.2236.

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Анотація:
In this paper, Condition of Substance Search (COS) algorithm is introduced to solve optimal reactive power dispatch problem. The Condition of Substance Search (COS) algorithm is based on the simulation of the shape of substance incidence. In Condition of Substance Search (COS) algorithm, individuals follow molecules which interrelate to each other by using evolutionary operations which are based on the corporal principles of the thermal-energy motion mechanism. The algorithm is developed by considering each condition of substance in harmony with different exploration–exploitation ratio. The ev
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3

Tapoi, C. "Comorbidity of Substance Use Disorders and Eating Disorders: a major concern for mental health care professionals." European Psychiatry 65, S1 (2022): S578. http://dx.doi.org/10.1192/j.eurpsy.2022.1481.

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Анотація:
Introduction During the last 30 years, many studies have shown a high prevalence of substance use among patients diagnosed with an Eating Disorder (ED). Almost 50% of the patients with ED have a history of substance use, and 35% of the patients that seek help for an addiction disorder also meet criteria for ED. Nevertheless, both substance abuse specialists and pratictioners with expertise in ED have difficulties in treating these dually diagnosed patients. Objectives The aim of this study is to emphasize the importance of assessing substance use in patients with ED and disturbed eating behavi
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4

Nwonu, Chukwunwike N., and Patience C. Nwonu. "Pharmaceutical and Non-Pharmaceutical Therapies in Substance Use Disorder." Scholars Bulletin 11, no. 05 (2025): 81–90. https://doi.org/10.36348/sb.2025.v11i05.002.

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The use of substances for recreational and other non-medical purposes is alarming in the society. The trend of substance use globally has been phenomenally startling in the last five decades, and has assumed epidemic and worrisome proportions in recent times. A significant number of these substances are used in the treatment of diverse clinical conditions. Objective: The work discussed the protocols for rehabilitation and recovery from substance addiction, strategies for prevention, principles underlying the treatment of substance use disorder, and the various therapeutic measures for containi
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5

Handu, Deepa, Kim Stote, and Tami Piemonte. "Evaluating Bioactive-Substance-Based Interventions for Adults with MASLD: Results from a Systematic Scoping Review." Nutrients 17, no. 3 (2025): 453. https://doi.org/10.3390/nu17030453.

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Objective: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a chronic condition affecting a broad population. This review aimed to identify and summarize the current evidence on bioactive-substance-based interventions for adults with MASLD, formerly known as nonalcoholic fatty liver disease (NAFLD), covering publications from 2000 to 2023. Methods: A search was conducted across six databases (MEDLINE, CINAHL, Cochrane CENTRAL, Cochrane Database of Systematic Reviews, Food Science Source, and SPORTDiscus) for randomized controlled trials and other study types (e.g., prospecti
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6

Nitzburg, George, Ingmar Weber, and Elad Yom-Tov. "Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis." Journal of Medical Internet Research 21, no. 5 (2019): e10946. http://dx.doi.org/10.2196/10946.

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Background Brief intervention is a critical method for identifying patients with problematic substance use in primary care settings and for motivating them to consider treatment options. However, despite considerable evidence of delay discounting in patients with substance use disorders, most brief advice by physicians focuses on the long-term negative medical consequences, which may not be the best way to motivate patients to seek treatment information. Objective Identification of the specific symptoms that most motivate individuals to seek treatment information may offer insights for further
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7

Miura, Takeshi, Chiemi Miura, Yasuko Konda, and Kohei Yamauchi. "Spermatogenesis-preventing substance in Japanese eel." Development 129, no. 11 (2002): 2689–97. http://dx.doi.org/10.1242/dev.129.11.2689.

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Анотація:
Under fresh-water cultivation conditions, spermatogenesis in the Japanese eel is arrested at an immature stage before initiation of spermatogonial proliferation. A single injection of human chorionic gonadotropin can, however, induce complete spermatogenesis, which suggests that spermatogenesis-preventing substances may be present in eel testis. To determine whether such substances exist, we have applied a subtractive hybridisation method to identify genes whose expression is suppressed after human chorionic gonadotropin treatment in vivo. We found one previously unidentified cDNA clone that w
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8

Emmanuel, Godwin Omokhagbo, Folahanmi Tomiwa Akinsolu, Olunike Rebecca Abodunrin, and Oliver Chukwujekwu Ezechi. "Prevalence and patterns of substance use in West Africa: A systematic review and meta-analysis." PLOS Global Public Health 4, no. 12 (2024): e0004019. https://doi.org/10.1371/journal.pgph.0004019.

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Анотація:
Introduction Substance use is a growing public health concern in West Africa, contributing to significant morbidity, mortality, and socioeconomic challenges. Despite the increasing prevalence, comprehensive data on the patterns and factors influencing substance use in the region remain limited. This systematic review and meta-analysis aim to synthesize existing research on the prevalence and patterns of substance use in West Africa, providing critical insights for developing targeted interventions and policies. Methodology This study followed the Preferred Reporting Items for Systematic Review
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9

Balthazar, Ellen Bedinhelo, Loraine Vivian Gaino, Letícia Yamawaka de Almeida, Jaqueline Lemos de Oliveira, and Jacqueline de Souza. "Risk factors for substance use: perception of student leaders." Revista Brasileira de Enfermagem 71, suppl 5 (2018): 2116–22. http://dx.doi.org/10.1590/0034-7167-2017-0587.

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ABSTRACT Objective: to analyze the perceptions of student leaders of the undergraduate course in Nursing about the motivations and/or risk factors for substance use in the university environment. Method: qualitative, transversal, descriptive study developed in a university campus in the state of São Paulo. Thirty members of associations affiliated with the course in Nursing participated. A questionnaire and a semi-structured interview were used, and the information was subjected to content analysis. Results: the influence of the social environment was the central element in the results. The ci
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10

Yamskova, О. V., D. V. Kurilov, I. V. Zavarzin, М. S. Krasnov, and T. V. Voronkova. "Effects of the Impact of Water-Soluble Forms of Fullerenes and Their Derivatives on Plants Metabolism and Yield of Agricultural Crops." Успехи современной биологии 143, no. 2 (2023): 165–79. http://dx.doi.org/10.31857/s0042132423020102.

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The search for effective and environmentally friendly plant growth regulators in modern conditions makes it possible to identify and reduce the impact on plant development, its metabolic processes, the biomass of its various parts and crops. Substances with the least toxicity to living organisms, which are of particular interest in this field, in particular, these include C60, C70 fullerenes and their derivatives. This paper describes the impact of both fullerenes themselves and their derivatives on plant growth, yield, effects, metabolic and morphological changes observed depending on the pro
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11

Rohner, Henrik, Nikolas Gaspar, Alexandra Philipsen, and Marcel Schulze. "Prevalence of Attention Deficit Hyperactivity Disorder (ADHD) among Substance Use Disorder (SUD) Populations: Meta-Analysis." International Journal of Environmental Research and Public Health 20, no. 2 (2023): 1275. http://dx.doi.org/10.3390/ijerph20021275.

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Анотація:
(1) Background: Attention deficit hyperactivity disorder (ADHD) is characterized by a persistent pattern of age-inappropriate levels of inattention and/or hyperactivity/impulsivity that results in functional impairment at work, education, or hobbies and affects family life, social contacts, and self-confidence. ADHD is a comorbid condition associated with a prognosis of severe substance use disorder (SUD) and the early onset of such. The aim of this meta-analysis was to obtain the best estimate of the prevalence of ADHD in SUD populations. (2) Methods: A literature research was conducted using
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12

Martinez-Raga, Jose, Nestor Szerman, Carlos Knecht, and Raquel de Alvaro. "Attention deficit hyperactivity disorder and dual disorders. Educational needs for an underdiagnosed condition." International Journal of Adolescent Medicine and Health 25, no. 3 (2013): 231–43. http://dx.doi.org/10.1515/ijamh-2013-0057.

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Анотація:
Abstract A wide range of comorbid psychiatric disorders overlap with attention-deficit hyperactivity disorder (ADHD) across the life span. There is a robust and complex link between ADHD and substance use disorders (SUD). The aim of this report was to review the neurobiological and other vulnerability factors explaining the comorbidity of ADHD and an addictive disorder, as well as the key aspects of the assessment and diagnosis of dually diagnosed ADHD patients. A comprehensive and systematic search of relevant databases (PubMed, Embase, and PsychINFO) was conducted to identify studies publish
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13

Noel, Christopher. "Evidence for the use of “medical marijuana” in psychiatric and neurologic disorders." Mental Health Clinician 7, no. 1 (2017): 29–38. http://dx.doi.org/10.9740/mhc.2017.01.029.

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Abstract Introduction: Cannabis is listed as a Schedule I substance under the Controlled Substances Act of 1970, meaning the US federal government defines it as an illegal drug that has high potential for abuse and no established medical use; however, half of the states in the nation have enacted “medical marijuana” (MM) laws. Clinicians must be aware of the evidence for and against the use of MM in their patients who may consider using this substance. Methods: A PubMed database search was performed using the text string: “Cannabis”[Mesh] OR “Marijuana Abuse”[Mesh] OR “Medical Marijuana”[Mesh]
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14

Kovyrshina, Anastasia A., Artem A. Bakal, Мariia S. Saveleva, Irina Yu Goryacheva, and Polina A. Demina. "Dependence of physical-chemical properties of fluorescent hybrid polymer carriers on the conditions of hydrothermal synthesis." Izvestiya of Saratov University. Chemistry. Biology. Ecology 24, no. 1 (2024): 15–27. http://dx.doi.org/10.18500/1816-9775-2024-24-1-15-27.

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Currently, the search for new types of carriers for low-molecular weight substances, as well as the development of optimal methods for the effective encapsulation of these substances are important tasks of modern chemistry and pharmacology. However, there are still limitations in this area, among which one of the most significant is the lack of the optimal carrier capable of stably retaining a low-molecular weight substance. The work presents hybrid polymer structures obtained by in situ hydrothermal synthesis as an effective candidate for these purposes. The fluorescent dye rhodamine B has be
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15

Rojas-Huerta, Bryan, Aranza Escandón-Wong, and Sandra Michel Quiroz-Heredia. "Predictores de Respuesta al Litio en el Trastorno Bipolar: Una Revisión Sistemática." Revista de la Asociación Psiquiatrica Mexicana, A.C 4, no. 2 (2024): 16–26. https://doi.org/10.5281/zenodo.14523470.

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Background This systematic review examines predictors of lithium response in bipolar disorder, a condition where lithium is a first-line treatment but benefits only 50% of patients. Through a comprehensive search of global databases, 20 high-quality studies were selected and analyzed using validated appraisal tools. Key findings indicate favorable response predictors include an episodic course of illness, low psychiatric comorbidity, absence of psychotic episodes, and genetic and neuroimaging markers. Conversely, mixed episodes and substance use predict poor outcomes. These insights emphasize
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16

Platt, Keith Allen. "Mindfulness and Self-Compassion Based Interventions for Substance Use Disorders: A Literature Review." JOURNAL OF SOCIAL SCIENCE RESEARCH 12, no. 1 (2018): 2619–33. http://dx.doi.org/10.24297/jssr.v12i1.7298.

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This literature review examines eight peer reviewed studies reporting on the efficacy of mindfulness-based and self-compassion-based interventions for adults diagnosed with substance use disorders. Prevalence of substance use disorders is provided, and relevant definitions are discussed. The syndrome model of addiction is advanced as an etiological explanation, and the search methodology described. Results of this literature review support mindfulness training as an effective intervention for substance use disorders. Only one study supporting self-compassion as an effective intervention for su
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17

Fasesan, OA. "Legalisation and Liberalisation of Cannabis: The Benefits and Drawbacks of the Global Trend." Annals of Health Research 8, no. 3 (2022): 165–76. http://dx.doi.org/10.30442/ahr.0803-01-168.

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Cannabis sativa is a complex domesticated plant that has an unstable taxonomy. It is the most utilised illicit substance that has gained prominence in some parts of the world as it is used for therapeutic and recreational purposes. C. Sativa has also been used to manage numerous medical conditions since antiquity. The pharmacological benefits of C. sativa are still subject to intense research due to inconsistent outcomes. C. sativa, like other psychoactive substances, has both medical and psychological side effects. Despite the lack of knowledge, medical practitioners continue to recommend thi
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18

Mijnster, Teus, Gretha J. Boersma, Esther Meijer, and Marike Lancel. "Effectivity of (Personalized) Cognitive Behavioral Therapy for Insomnia in Mental Health Populations and the Elderly: An Overview." Journal of Personalized Medicine 12, no. 7 (2022): 1070. http://dx.doi.org/10.3390/jpm12071070.

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Insomnia is very prevalent in psychiatry and is considered a transdiagnostic symptom of mental disorders. Yet, it is not only a consequence of a mental condition but may also exert detrimental effects on psychiatric symptom severity and therapeutic response; thus, adequate insomnia treatment is particularly important in psychiatric populations. The first choice of intervention is cognitive behavioral therapy for insomnia (CBT-I) as it is rather effective, also in the long run without side effects. It is offered in various forms, ranging from in-person therapy to internet-delivered applications
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19

Belfiore, Cecilia Ilaria, Valeria Galofaro, Deborah Cotroneo, et al. "A Multi-Level Analysis of Biological, Social, and Psychological Determinants of Substance Use Disorder and Co-Occurring Mental Health Outcomes." Psychoactives 3, no. 2 (2024): 194–214. http://dx.doi.org/10.3390/psychoactives3020013.

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We explored the intricate interplay of biological, social, and psychological factors contributing to substance use disorder (SUD) and co-occurring psychiatric symptoms. Drug misuse is a global concern, with increasing prevalence rates affecting mental well-being and safety. The spectrum of SUD includes polysubstance users, posing challenges for treatment and associated health outcomes. Various psychoactive substances like cannabis, hallucinogens, opioids, and stimulants impact addiction vulnerability, with marijuana being widely used globally. Gender differences in SUD prevalence have narrowed
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20

Abdulrahman, Samir Khateiri Mohammed Saeed Alshulayyil Tahani Saleh Alsaery Mohammed Abdulhakim Al Hattab Turki Habib AlShammari Shuruq Abdullah Alamri Eman Mohammad AlFaraj Noha Tariq Alroumi Ghaida Mohammad Ahmad Faisal Mohsen Alkhammash. "ROLE OF IMAGING IN BONE DISORDERS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 11 (2018): 12655–60. https://doi.org/10.5281/zenodo.1492557.

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<strong><em>Introduction:</em></strong><em> The term &lsquo;metabolic diseases of bone&rsquo; refers to the group of conditions where abnormalities occur to the bony mass, hemostasis of bone-related substance, the turnover of bone tissue, or the growth of bones. The most common disease in this group is osteoporosis which leads to a generalized bony mass loss along with destruction and degeneration of the microarchitecture of the bone tissue. In cases where impairment occurs during the development of chondrocytes, which is usually associated with growth plate cartilage mineralization failure, t
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21

Skryabin, V. Yu. "In search of inspiration: Psychoactive substances in jazz history." V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY 59, no. 1 (2025): 104–13. https://doi.org/10.31363/2313-7053-2025-1-954.

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Throughout the history of jazz, its close association with psychoactive substances has been one of the most controversial and debated topics. From the smoke-filled clubs of the 1920s, where attendees smoked marijuana freely, to the underground jam sessions of the 1960s, where heroin reigned supreme, the lifestyles of jazz musicians have often included illicit substances. The careers of many talented jazz musicians have been sidelined or prematurely cut short due to addiction to drugs and/or alcohol. The lives of the most famous of them, from Louis Armstrong and Milton Mezzrow to Charlie Parker
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22

Bazzi, Ali, Mohammad Javad Ghazanfari, Iraj Aghaei, et al. "A Systematic Review of Knowledge and Attitude of Nurses Towards Substance Use or Users." Addiction and Health 16, no. 4 (2024): 297–304. https://doi.org/10.34172/ahj.1326.

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Background: Substance use disorders (SUDs) pose substantial challenges to society, creating widespread negative effects. Given their frequent and direct contact with patients, nurses hold a vital position in managing and addressing these disorders. This systematic review aimed to examine nurses’ understanding of substance use and their perceptions of individuals affected by these conditions. Methods: This systematic review involved a comprehensive search of online databases such as PubMed, Web of Science, and Scopus, utilizing relevant keywords up to July 9, 2021. Only studies published in Eng
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23

Sosa-Moscoso, Bernardo, Alina Rivadeneira-Limongi, Filip Moncayo, et al. "Axis I Psychiatric Disorders and Substance Abuse: A Systematic Review of Neuroimaging Findings." Journal of Clinical Medicine 14, no. 7 (2025): 2156. https://doi.org/10.3390/jcm14072156.

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Background/Objectives: The present systematic review analyses the neuroradiological findings in subjects with axis I psychiatric disorders (i.e., bipolar, major depressive, schizophrenic, anxiety, and post-traumatic stress disorders) and comorbid substance use disorder in order to elucidate the organic changes that occur in the brains of people suffering from both conditions. Methods: We analysed and compared the different neuroimaging findings extracted from 93 studies and 10,823 patients; articles were obtained from three databases (Scopus, PubMed [Medline], and the Cochrane Controlled Regis
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24

Lawal, Qudus, Shatha Shibib, and Adeola Animashaun. "Cannabis-Based Medicinal Products in the Treatment of Post-Traumatic Stress Disorder in Children and Young People: A Literature Review." BJPsych Open 11, S1 (2025): S54—S55. https://doi.org/10.1192/bjo.2025.10171.

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Aims: Post-traumatic stress disorder (PTSD) is a condition that may develop following exposure to a highly threatening or horrific event or series of events. PTSD can affect people across all age groups with extensive impact on functioning and is often associated with psychoactive substance misuse. Cannabis is one of the most abused psychoactive substances worldwide, with users reporting anxiolytic benefits. Cannabis-based medicinal products (CBMPs) have gained more attention and interest over the past few years due to changes in the legislation around cannabis worldwide. Research has shown ca
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25

Kuppens, Sofie, Simon C. Moore, Vanessa Gross, Emily Lowthian, and Andy P. Siddaway. "The Enduring Effects of Parental Alcohol, Tobacco, and Drug Use on Child Well-being: A Multilevel Meta-Analysis." Development and Psychopathology 32, no. 2 (2019): 765–78. http://dx.doi.org/10.1017/s0954579419000749.

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AbstractThe effects of psychoactive substance abuse are not limited to the user, but extend to the entire family system, with children of substance abusers being particularly at risk. This meta-analysis attempted to quantify the longitudinal relationship between parental alcohol, tobacco, and drug use and child well-being, investigating variation across a range of substance and well-being indices and other potential moderators. We performed a literature search of peer-reviewed, English language, longitudinal observational studies that reported outcomes for children aged 0 to 18 years. In total
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26

Nkporbu, A. K., and P. C. Stanley. "Does Psychoactive Substance Use Affect Academic Performance of Medical Students? A Systematic Review." International Neuropsychiatric Disease Journal 19, no. 2 (2023): 39–46. http://dx.doi.org/10.9734/indj/2023/v19i2371.

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Background: The use of illicit drugs, alcohol, and tobacco is very common among medical students. Problems related to substance usage are currently of concern on a global scale. Despite this, the condition is frequently misdiagnosed because students attempt to conceal their issues and do not seek professional assistance.&#x0D; Aim: To investigate how drug usage affects medical students' academic performance.&#x0D; Design: A systematic review.&#x0D; Data Sources: Systematic search for worldwide published literature from PsycINFO, Cochrane, Google Scholar, Science Direct, PubMed, and WHOLIS. &#x
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27

Shevchuk, M. M., and L. I. Volos. "THERAPEUTIC POTENTIAL OF CANNABIDIOL: THE MOST IMPORTANT ACHIEVEMENTS ON THE WAY TO A NEW ERA." Medical Science of Ukraine (MSU) 19, no. 2 (2023): 132–41. http://dx.doi.org/10.32345/2664-4738.2.2023.17.

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Background. Cannabidiol (CBD), found in Cannabis sativa (hemp), is a non-psychoactive phytochemical substance that has gained considerable popularity over the past decade. Cannabidiol is the main phytocannabinoid, its share in the plant extract can reach 40%. Cannabidiol does not have any of the psychoactive properties that tetrahydrocannabinol (THC) and has a significant advantage for clinical use. Studies of cannabidiol involve studies of cognitive, anxiety and movement disorders, and chronic pain, but there is a lack of high-quality evidence that cannabidiol is effective for these condition
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28

Smedfors, Gabriella, Felicia Jennysdotter Olofsgård, Anna Steinberg, Elisabet Waldenlind, Caroline Ran, and Andrea Carmine Belin. "Use of Prescribed and Non-Prescribed Treatments for Cluster Headache in a Swedish Cohort." Brain Sciences 14, no. 4 (2024): 348. http://dx.doi.org/10.3390/brainsci14040348.

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Background: Cluster headache (CH) is a debilitating condition, but current therapies leave CH patients in pain. The extent of this problem in Sweden is unknown. Methods: An anonymized questionnaire was sent to 479 Swedish CH patients to investigate patterns and perceived effects of treatments. Results: Three hundred fourteen answers were analyzed. The population was representative regarding age of onset and sex. Less than half (46%) were satisfied with their abortive treatments, 19% terminated functioning abortive treatments due to side effects. Additionally, 17% of chronic CH patients had not
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29

Khelvin Risandi and Hari Sutra Disemadi. "PEMALSUAN MEREK SEPATU DI INDONESIA: PENGATURAN DAN SANKSI?" Jurnal Komunikasi Hukum (JKH) 8, no. 2 (2022): 315–26. http://dx.doi.org/10.23887/jkh.v8i2.51029.

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The laws and regulations in Indonesia have regulated brand counterfeiting, but the cases have not decreased yet. The rise of brand counterfeiting is caused by the condition of society and ineffective laws and regulations. Previous similar studies have discussed the trademark registration procedure and its obstacles as well as the study of mark cancellation, while this research focuses on the regulation and sanctions for brand counterfeiting. The purpose of the study was to find out how the legal arrangements against the perpetrators of counterfeiting shoe brands spread in Indonesia. This study
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30

Magor-Blatch, Lynne, Navjot Bhullar, Bronwyn Thomson, and Einar Thorsteinsson. "A systematic review of studies examining effectiveness of therapeutic communities." Therapeutic Communities: The International Journal of Therapeutic Communities 35, no. 4 (2014): 168–84. http://dx.doi.org/10.1108/tc-07-2013-0024.

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Purpose – The purpose of this paper is to systematically review quantitative research since 2000 on the effectiveness of residential therapeutic communities (TCs) for the treatment of substance-use disorders with reference to substance-use, crime, mental health and social engagement outcomes. Design/methodology/approach – A systematic search with broad inclusion criteria resulted in the review of 11 studies. The studies investigated community-based TCs, as well as TCs modified for prisoners, prisoners transitioning to community living and TCs for individuals with co-occurring substance-use and
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31

Berhane, Asmeret, Ava Hashemi, Ayyub Imtiaz, Adil Elahi, and Muhammad Zaidi. "Pseudo-Wellens Syndrome: Demonstrating the Importance of Electrocardiogram in Emergency Psychiatric Patients." CNS Spectrums 29, no. 5 (2024): 480–81. https://doi.org/10.1017/s1092852924001287.

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IntroductionPseudo-Wellens syndrome (PWS) is a rare but clinically significant condition characterized by electrocardiogram (ECG) abnormalities that mimic acute ST-segment elevation myocardial infarction (STEMI) in the absence of obstructive lesions on coronary angiography. The occurrence of PWS should be on the differential for any patient who visits the Emergency Room (ER) with known and/or suspected drug overdose. This will avoid the potential for inappropriate invasive diagnostic modalities in otherwise cardiac healthy individuals. This literature review aims to explore the ECG changes in
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32

Quilty, Lena, Branka Agic, Michelle Coombs, et al. "Benefits of Digital Health Resources for Substance Use Concerns in Women: Scoping Review." JMIR Mental Health 8, no. 6 (2021): e25952. http://dx.doi.org/10.2196/25952.

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Background Digital health resources are being increasingly used to support women with substance use concerns. Although empirical research has demonstrated that these resources have promise, the available evidence for their benefit in women requires further investigation. Evidence supports the capacity of interventions that are sex-, gender-, and trauma-informed to improve treatment access and outcomes and to reduce health system challenges and disparities. Indeed, both sex- and gender-specific approaches are critical to improve health and gender equity. Violence and trauma are frequent among t
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33

Khaustova, O. O., A. E. Asanova, N. O. Dzeruzhynska, and M. M. Matiash. "Peculiarities of personalized selection of antipsychotic drugs for schizophrenia treatment." Medicni perspektivi 29, no. 1 (2024): 43–52. http://dx.doi.org/10.26641/2307-0404.2024.1.300499.

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Анотація:
Determining the optimal antipsychotic drugs, its effective dose, duration of therapy, form, and route of administration play a key role in the treatment of schizophrenia. In addition, special attention should be paid to the effectiveness of using different forms of antipsychotic drugs, in particular, the orally disintegrating form as exemplified by olanzapine. To study the peculiarities of a personalized approach in the use of antipsychotic drugs to achieve more effective results in treating schizophrenia, a content analysis was conducted using Ukrainian and English-language publications for t
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34

Khaustova, O.O., A.E. Asanova, N.O. Dzeruzhynska, and M.M. Matiash. "Peculiarities of personalized selection of antipsychotic drugs for schizophrenia treatment." Medicni perspektivi 29, no. 1 (2024): 43–52. https://doi.org/10.26641/2307-0404.2024.1.300499.

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Анотація:
Determining the optimal antipsychotic drugs, its effective dose, duration of therapy, form, and route of administration play a key role in the treatment of schizophrenia. In addition, special attention should be paid to the effectiveness of using different forms of antipsychotic drugs, in particular, the orally disintegrating form as exemplified by olanzapine. To study the peculiarities of a personalized approach in the use of antipsychotic drugs to achieve more effective results in treating schizophrenia, a content analysis was conducted using Ukrainian and English-language publications for t
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35

Nataliia, Bevz, and Mishchenko Volodymyr. "Development of a design research for determining the quality indicators of potential API. 1. newly synthesized substances for primary pharmacological screening." ScienceRise: Pharmaceutical Science, no. 5(21) (October 31, 2019): 18–26. https://doi.org/10.15587/2519-4852.2019.182279.

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The constant growth in the world of medicinal products of synthetic origin determines the search, directed synthesis and pharmacological studies of new biologically active substances. The establishment of the structure of the substance and the study of physical and chemical properties requires the use of a number of methods and tests that allow obtaining a substance with &quot;pharmacopoeial quality&quot; already at the stage of synthesis of potential API. Changes in the further conditions of synthesis, solvents for crystallization, etc. can lead to a change in the profile of impurities and th
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36

Equihua-Benítez, Ana Clementina, and Fabio García-García. "Healthy Sleep, Orexin System and Addiction." Revista Internacional de Investigación en Adicciones 10, no. 1 (2024): 80–90. http://dx.doi.org/10.28931/riiad.2024.1.09.

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Introduction: sleep disturbances are often reported in the context of depression, anxiety, and substance abuse disorder, observations that have strengthened the idea that there is an underlying link between them. Recently, the orexinergic system has been proposed as a possible common regulator, as orexinergic innervation reaches both sleep and wake-promoting centers and the mesolimbic pathway, potentially allowing orexinergic stimuli to promote wakefulness and addiction concurrently. Objective: to describe the involvement of the orexinergic system in behaviors such as sleep and substance abuse
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37

Zuccon, Marco, Eleonora Topino, Alessandro Musetti, and Alessio Gori. "Psychodynamic Therapies for the Treatment of Substance Addictions: A PRISMA Meta-Analysis." Journal of Personalized Medicine 13, no. 10 (2023): 1469. http://dx.doi.org/10.3390/jpm13101469.

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The aim of this meta-analysis was to compare psychodynamic with other treatments in studies of substance addiction. The literature search was conducted using the PubMed, Web of Science, Cohcrane library, SCOPUS, and Onesearch databases. All studies comparing psychodynamic therapy with other types of psychological interventions for Substance Use Disorder were eligible. Three outcomes were considered to compare intervention performance: substance use, participation in treatment and other symptomatic conditions (OSCs). Hedges’ G was used to measure effect size. The Revised Cochrane Risk of Bias t
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38

Arkadiy Vasil’evich, OVCHARENKO. "Geophysical search for fragments of the Sterlitamak meteorite." NEWS of the Ural State Mining University, no. 2 (June 15, 2021): 123–33. http://dx.doi.org/10.21440/2307-2091-2021-2-123-133.

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Анотація:
Relevance is determined by the fact that meteorites are of great importance for the direct study of the substance of the Universe, therefore, when new meteorites fall, maximum efforts are made to detect them and study the conditions of the fall. The purpose of the work is to further study the meteorite crater and search for large fragments of the Sterlitamak meteorite not found at the first stage of study using geophysical methods. The story of the fall and searches for the main fragment of the Sterlitamak meteorite, which fell on August 17, 1990 at 23 h 25 min, on the field of the Sterlitamak
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39

Saleem Kbah, Sadeem Nabeel, Tian Swee Tan, Jahanzeb Sheikh, et al. "Review on Fundamental of Electroencephalography and Detection Techniques in Substance and Behavioral Addiction." Journal of Human Centered Technology 4, no. 1 (2025): 78–85. https://doi.org/10.11113/humentech.v4n1.98.

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Addiction is a chronic relapsing brain disease associated with substantial individual and societal burden. It includes complex phyco-physiological conditions and can be recognized by compulsive and harmful behaviors towards a substance or activity, despite negative consequences or “bio-psycho-social-spiritual” disorder. This paper aims to comprehensively review previous research which applied machine learning to electroencephalography (EEG) signals for automatic detection of addiction. A systematic search was done on 200 relevant papers published between 2018 - 2023. The previous studies appli
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40

Козлова, М. А., and В. А. Шаманский. "SEARCHING FOR AN EXTREME COMPONENT CONTENT IN A REACTING SYSTEM USING GRAPH OF CHEMICAL REACTIONS." Proceedings in Cybernetics 22, no. 1 (2023): 21–28. http://dx.doi.org/10.35266/1999-7604-2023-1-21-28.

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The article presents a technique for calculating a maximum amount of a substance in a closed system using a step-by-step graph of chemical reactions. A list of probable one- and two-particle reversible reactions is generated based on the substances that may be a part of the reacting system. The list is narrowed down according to the research objectives and conditions of the reacting system. The obtained list corresponds to the incidence matrix, which is suitable for analyzing the graph via a computer. The search for the maximum amount of the component in question is conducted through the compa
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41

Kaur, Harsimar, and Saksham Sharma. "Memantine in Psychiatry: An Underutilized Therapeutic Breakthrough?" BJPsych Open 11, S1 (2025): S328. https://doi.org/10.1192/bjo.2025.10795.

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Aims: Memantine, an N-methyl-D-aspartate receptor antagonist, is primarily approved for the treatment of Alzheimer’s disease and other forms of dementia. However, multiple studies have explored its potential applications in psychiatric disorders. This literature review aims to evaluate existing evidence on the efficacy of memantine in conditions such as trichotillomania, skin picking disorder, depression, bipolar disorder, obsessive-compulsive disorder, ADHD, autism spectrum disorder, substance use disorder, schizophrenia, and reducing cognitive effects of electroconvulsive therapy. The review
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42

Figueiredo, I. M., I. Cargaleiro, and M. Nascimento. "Drugs and high hospitalization rate: are they related?" European Psychiatry 66, S1 (2023): S515—S516. http://dx.doi.org/10.1192/j.eurpsy.2023.1094.

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IntroductionSubstance use continues to be an important problem among mental health patients either as main diagnosis or as comorbidity. Acute care visits, including emergency department visits and hospitalizations, related to substance use disorders (SUD) are increasing and can be opportunities to engage individuals to get proper treatment (Suen LW et al. J Gen Intern Med 2022; 37(10):2420–2428). Both mental disorders and SUD lead to subsequent chronic physical conditions, premature death, suicide or overdose (Bennett AC. Public Health Rep 2019; 134(1):17-26) that can be accidental or not.24%
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43

López-Valverde, Nansi, Beatriz Pardal-Peláez, Antonio López-Valverde, et al. "Effectiveness of Propolis in the Treatment of Periodontal Disease: Updated Systematic Review with Meta-Analysis." Antioxidants 10, no. 2 (2021): 269. http://dx.doi.org/10.3390/antiox10020269.

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In recent times, the use of natural products has gained momentum, either as a treatment or as adjuvants for other drugs in the treatment of different conditions. Propolis is a natural substance produced by bees which has proven useful for treating periodontal disease. This systematic review and meta-analysis gather evidence of the effectiveness of propolis in this kind of condition. The MEDLINE, CENTRAL, PubMed, EMBASE and Web of Science databases were searched for scientific articles to identify the findings published up to October 2020. The MeSH phrases used in the search were: “periodontal
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44

Leung, Alexander K. C., and Kam Lun Hon. "Pica: A Common Condition that is Commonly Missed - An Update Review." Current Pediatric Reviews 15, no. 3 (2019): 164–69. http://dx.doi.org/10.2174/1573396315666190313163530.

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Background: Pica is a common condition in childhood that is commonly missed. Objective: To familiarize physicians with the clinical evaluation and management of children with pica. Methods: A PubMed search was completed in Clinical Queries using the key term "pica" OR “dirteating”. The search strategy included meta-analyses, randomized controlled trials, clinical trials, observational studies, and reviews. Only papers published in English literature were included in this review. The information retrieved from the above search was used in the compilation of the present article. Results: Pica re
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45

Knecht, Carlos, Raquel de Alvaro, Jose Martinez-Raga, and Vicent Balanza-Martinez. "Attention-deficit hyperactivity disorder (ADHD), substance use disorders, and criminality: a difficult problem with complex solutions." International Journal of Adolescent Medicine and Health 27, no. 2 (2015): 163–75. http://dx.doi.org/10.1515/ijamh-2015-5007.

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Abstract The association between attention-deficit hyperactivity disorder (ADHD) and criminality has been increasingly recognized as an important societal concern. Studies conducted in different settings have revealed high rates of ADHD among adolescent offenders. The risk for criminal behavior among individuals with ADHD is increased when there is psychiatric comorbidity, particularly conduct disorder and substance use disorder. In the present report, it is aimed to systematically review the literature on the epidemiological, neurobiological, and other risk factors contributing to this associ
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46

Akosile, Adeola Y., Babangida Tiyatiye, and Wole Akosile. "A Systematic Review on the Prevalence of Comorbid Substance Use Disorder in Obsessive–Compulsive Disorder Among the General Population." Psychoactives 4, no. 1 (2025): 2. https://doi.org/10.3390/psychoactives4010002.

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Background: To estimate the prevalence of co-occurring obsessive–compulsive disorder (OCD) with substance use disorder (SUD) in the general population. Methods: A comprehensive literature search was conducted on the prevalence of comorbid OCD and SUD in the general population using MEDLINE, PsycINFO, EMBASE and CINAHL. Using the keywords, relevant studies published between 1993 and 2021 were identified. These studies were analysed using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines and the guidelines for Meta-analysis for Observational Studies in Ep
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47

Tomáš, Jandáč, and Šťastná Lenka. "Prevalence of Dual Diagnoses among Children and Adolescents with Mental Health Conditions." Children 10, no. 2 (2023): 293. http://dx.doi.org/10.3390/children10020293.

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Background: The World Health Organisation defines dual diagnosis as the co-occurrence in the same individual of a psychoactive substance use disorder and another psychiatric disorder. Children and adolescents with dual diagnoses represent a significant public health burden in social and financial terms. Aims: The objective of the present paper is to provide a review of studies dealing with dual diagnoses and their prevalence among children and adolescents whose primary treatment involves psychiatric conditions. Methods: The PRISMA was used to conduct a systematic search. Articles published bet
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48

Fatseas, M. "ADHD and addictive disorders: What links?" European Psychiatry 30, S2 (2015): S28. http://dx.doi.org/10.1016/j.eurpsy.2015.09.085.

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Анотація:
The links between ADHD and addictive disorders have been the subject of a large number of studies showing a high prevalence rate of ADHD in substance abusing populations as well as an increased risk of substance use disorder (SUD) in ADHD patients that may be independent of other psychiatric conditions. High prevalence of ADHD has also been highlighted among individuals suffering from other addictive disorders such as pathological gambling. Adequate diagnosis of ADHD in SUD patients is challenged by phenomenological aspects of addiction and by frequently associated other psychiatric disorders
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49

Wright, Patrick, Zach Walsh, Shari Margolese, et al. "Canadian clinical practice guidelines for the use of plant-based cannabis and cannabinoid-based products in the management of chronic non-cancer pain and co-occurring conditions: protocol for a systematic literature review." BMJ Open 10, no. 5 (2020): e036114. http://dx.doi.org/10.1136/bmjopen-2019-036114.

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IntroductionChronic pain and co-occurring disorders, such as sleep disorders, anxiety, depression, post-traumatic stress disorder and substance use disorders, are among the most common conditions for which cannabis and cannabinoid-based products derived from the cannabis plant (CBP) are used for therapeutic purposes. However, healthcare providers report that they lack sufficient information on the risks, benefits and appropriate use of cannabis and CBP derived from the cannabis plant for therapeutic purposes.Methods and analysisWe will conduct a systematic review of studies investigating the u
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50

Kumar, Vaibhav, Jasleen Thakker, Abhishek Royal, Nikhil Bhanushali, and Ziad D. Baghdadi. "Oral Health and Hygiene Status of Global Transgender Population: A Living Systematic Review and Meta-Analysis." International Journal of Environmental Research and Public Health 22, no. 3 (2025): 433. https://doi.org/10.3390/ijerph22030433.

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Due to several interpersonal, social, and organizational challenges, dental health has been occasionally compromised in the transgender population. There is a lack of awareness among transgender persons to access affordable trans-competent oral health care. More information is required to identify and assess the oral health condition of this population in order to encourage better access to oral healthcare and effectively influence public health policy and practice. This systematic review aims to provide evidence about the status of oral health and hygiene of the transgender population across
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