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Статті в журналах з теми "Controlled Drug Delivery System"

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SHARMA, PRASHANT. "Pulsatile Drug Delivery System – A Novel Approach for Time and Spatial Controlled Drug Delivery." Journal of Pharmaceutical Technology, Research and Management 4, no. 1 (2016): 13–29. http://dx.doi.org/10.15415/jptrm.2016.41002.

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Disha A Deulkar, Jitendra A Kubde, Pooja R Hatwar, and Ravindrakumar L Bakal. "A review on transdermal drug delivery system." GSC Advanced Research and Reviews 18, no. 2 (2024): 347–61. http://dx.doi.org/10.30574/gscarr.2024.18.2.0052.

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Drugs that are applied topically are delivered using transdermal drug delivery devices. These are pharmaceutical preparations of varying sizes, containing one or more active ingredients, intended to be applied to the unbroken skin in order to deliver the active ingredient after passing through the skin barriers, and these avoid first pass metabolism. Today about 74% of drugs are taken orally and are not found effective as desired. To improve efficacy transdermal drug delivery system was emerged. A notable advantage of transdermal drug delivery compared to other methods like oral, topical, intr
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Disha, A. Deulkar, A. Kubde Jitendra, R. Hatwar Pooja, and L. Bakal Ravindrakumar. "A review on transdermal drug delivery system." GSC Advanced Research and Reviews 18, no. 2 (2024): 347–61. https://doi.org/10.5281/zenodo.11216528.

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Анотація:
Drugs that are applied topically are delivered using transdermal drug delivery devices. These are pharmaceutical preparations of varying sizes, containing one or more active ingredients, intended to be applied to the unbroken skin in order to deliver the active ingredient after passing through the skin barriers, and these avoid first pass metabolism. Today about 74% of drugs are taken orally and are not found effective as desired. To improve efficacy transdermal drug delivery system was emerged. A notable advantage of transdermal drug delivery compared to other methods like oral, topical, intr
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4

Gupta, Brahma Prakash, Navneet Thakur, Nishi P. Jain, Jitendra Banweer, and Surendra Jain. "Osmotically Controlled Drug Delivery System with Associated Drugs." Journal of Pharmacy & Pharmaceutical Sciences 13, no. 4 (2010): 571. http://dx.doi.org/10.18433/j38w25.

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Анотація:
Conventional drug delivery systems have slight control over their drug release and almost no control over the effective concentration at the target site. This kind of dosing pattern may result in constantly changing, unpredictable plasma concentrations. Drugs can be delivered in a controlled pattern over a long period of time by the controlled or modified release drug delivery systems. They include dosage forms for oral and transdermal administration as well as injectable and implantable systems. For most of drugs, oral route remains as the most acceptable route of administration. Certain mole
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Pandey, Parijat, Manisha Saini, and Neeta . "Mucoadhesive drug delivery system: an overview." Pharmaceutical and Biological Evaluations 4, no. 4 (2017): 183. http://dx.doi.org/10.26510/2394-0859.pbe.2017.29.

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The major objective of any dosage form is to deliver an optimum therapeutic amount of active agent to the proper site in the body to attain constant & maintenance of the desired drug concentration. Mucoadhesive drug delivery systems are effective delivery systems with various advantages as compared to other oral controlled release dosage forms in terms of drug delivery at specific sites with prolonged retention time of drugs at target sites. The main advantage of these systems includes avoiding first pass metabolism of the drugs and hence availability of high drug concentration at target s
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Tanvir, Karajagikar*1 Anil Panchal2 Vishal Madankar3. "Microsphere as Novel Drug Delivery System." International Journal of Scientific Research and Technology 2, no. 2 (2025): 65–69. https://doi.org/10.5281/zenodo.14836892.

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Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 µm. A welldesigned controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a given drug. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. One such approach is using microspheres as carriers for drugs. It is the reliable means to deliver the drug to the ta
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Prasanna, N. *1 Srilatha Ch. 2. Subrahmanyam C. V. S.3. "Osmotic Controlled Release Oral Delivery System: An Overview." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 530–58. https://doi.org/10.5281/zenodo.10810393.

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Osmotic drug delivery systems (ODDS) are a type of controlled release technology that utilizes the principles of osmosis to deliver drugs in a precise and sustained manner. These systems typically consist of a core containing the drug and an osmotic agent, surrounded by a semipermeable membrane. Water from the surrounding environment draws in through the membrane due to the osmotic pressure generated by the core, pushing the drug solution out through a predefined delivery orifice in a controlled manner. Osmotic drug delivery devices, such as the Rose and Nelson pump, Higuchi Leeper pump, Higuc
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Divya, M. Ramchandani* Brijesh R. Humbal and Bhulesh V. Paida. "Role of Nanoparticles in Drug Delivery System." Science World a monthly e magazine 2, no. 11 (2022): 1877–83. https://doi.org/10.5281/zenodo.7358409.

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Анотація:
Nanomedicine and nano delivery systems are new but rapidly developing science which serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. Novel drug delivery systems have several advantages over conventional multi dose therapy. Drug designing at the nanoscale has been of its potential advantages such as the possibility to modify properties like solubility, drug release profiles, diffusivity, bioavailability and immunogenicity. Nanoparticles can offer significant advantages in terms of high stability, high specificity, high drug c
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Rajput, Rajesh, K. M. K. Prasanna Kumar, D. S. Arya, et al. "Osmotic controlled drug delivery system (OSMO technology) and its impact on diabetes care." International Journal of Research in Medical Sciences 9, no. 1 (2020): 303. http://dx.doi.org/10.18203/2320-6012.ijrms20205861.

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Анотація:
Recently, focus on the development of controlled release drug delivery system has increased, as existing drugs exhibit certain pharmacokinetic limitations. The major goal of designing sustained release formulations is to improve the drug performance by prolonged duration of drug action, decreased frequency of dosing and reduced side effects by using smallest quantity of drug administered by the most suitable route. Osmotic-controlled release oral delivery system (OSMO technology) is the most promising strategy based system for sustained delivery of drug. Drug can be delivered in a controlled m
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S.K, Ghate Dr. D.M.Sakarkar. "DEVELOPMENT AND EVALUATION OF OSMOTICALLY CONTROLLED ORAL DRUG DELIVERY SYSTEM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH 07, no. 09 (2017): 459–70. https://doi.org/10.5281/zenodo.1036415.

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Анотація:
Conventional drug delivery systems have slight control over their drug release and almost no control over the effective concentration at the target site. This kind of dosing pattern may result in constantly changing, unpredictable plasma concentrations. Drugs can be delivered in a controlled pattern over a long period of time by the controlled or modified release drug delivery systems. They include dosage forms for oral and transdermal administration as well as injectable and implantable systems. For most of drugs, oral route remains as the most acceptable route of administration. Certain mole
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Дисертації з теми "Controlled Drug Delivery System"

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Zaher, Amir. "Remotely controlled drug delivery systems." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/57611.

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Implantable drug delivery is becoming an increasingly important field of research, providing great potential for a wide range of flexible and low cost solutions for localized treatment of chronically debilitating diseases. This dissertation presents work that encompasses several approaches for the remote triggering, powering, and control of micro drug delivery devices and systems, designed with remote-controllability, minimal power requirements, biocompatibility, and the potential for minimally invasive implantation in mind. The control mechanisms used rely on microtechnology, nanotechnology,
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Lee, Yan Sim. "The development of controlled-chemotherapy drug delivery system." Thesis, University of Bath, 2009. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512304.

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The aim of this thesis was to develop biodegradable devices loaded with chemotherapy drug. The system is targeted for advanced ovarian cancer treatment through the intraperitoneal (IP) route of administration. Polylactide-co-glycolide (PLGA) was selected as the model biodegradable polymer to produce drug-loaded microsphere, hollow and solid fibres. Copolymer PLGA with three different lactic:glycolic acids ratios; 50:50, 65:35 and 75:25 were used in order to compare their drug loading capacities and in vitro drug release profiles. Cisplatin, a cytotoxic drug with proven activity against ovarian
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Feely, L. C. "Controlled release hydroxypropylmethylcellulose mini-matrices." Thesis, University of Nottingham, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.373348.

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Goettsche, Thorsten [Verfasser], Roland [Akademischer Betreuer] Zengerle, and Gerald A. [Akademischer Betreuer] Urban. "IntelliDrug - controlled, oral drug delivery system as tooth implant." Freiburg : Universität, 2016. http://d-nb.info/1128574195/34.

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Chia, Leonard Sze Onn. "Investigating controlled release pulmonary drug delivery systems." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/273209.

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The therapeutic effect of pulmonary drug delivery systems is limited by its rapid clearance from the lungs by robust clearance mechanisms. By controlling the release of drugs, the therapeutic effect of pulmonary drug delivery systems, as well as patient convenience and compliance could be improved by reducing the number of times drugs need to be administered. In this study, two controlled pulmonary drug delivery systems for drugs of different solubilities were investigated and they were characterised for their viability as effective controlled release pulmonary drug delivery systems, particula
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Mahaguna, Vorapann. "Investigation of cellulose ether polymers in controlled drug delivery." Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3037524.

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Babu, Kavitha Mary Vadakkel. "The Development of a Novel Controlled Release Drug Delivery System." The University of Waikato, 2007. http://hdl.handle.net/10289/2590.

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The aim of this research was to formulate, characterise and assess the feasibility of a novel drug delivery system known as the in situ gelling matrix (ISGM) where a hydrophilic polymer is suspended in a non-aqueous solvent that converts into a gel when injected subcutaneously or intramuscularly thus giving a controlled release matrix for a drug. Although the concept has been patented with claims that this kind of drug delivery is achievable in theory for a wide variety of candidate substances, actual formulation studies for making a commercially viable product for this technology are complet
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Rodriguez, Lidia Betsabe. "Controlled Release System for Localized and Sustained Drug Delivery Applications." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1365107103.

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Zhang, Qilei. "NMR and MRI studies of controlled release drug delivery systems." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610886.

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Paulsson, Mattias. "Controlled Release Gel Formulations for Mucosal Drug Delivery." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5173-X/.

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Книги з теми "Controlled Drug Delivery System"

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Rossi, Filippo, Giuseppe Perale, and Maurizio Masi. Controlled Drug Delivery Systems. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-02288-8.

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Bret, Berner, and Dinh Steven M, eds. Electronically controlled drug delivery. CRC Press, 1998.

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Frost & Sullivan., ed. Programmed drug delivery system markets. Frost & Sullivan, 1988.

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4

Chien, Yie W. Novel drug delivery systems. 2nd ed. M. Dekker, 1992.

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5

Kinam, Park, ed. Controlled drug delivery: Challenges and strategies. American Chemical Society, 1997.

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6

D, Li Xiaoling Ph, and Jasti Bhaskara R, eds. Design of controlled release drug delivery systems. McGraw-Hill, 2006.

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7

M, Dinh Steven, and Liu Puchun, eds. Advances in controlled drug delivery: Science, technology, and products. American Chemical Society, 2003.

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8

1954-, Mitra Ashim K., ed. Ophthalmic drug delivery systems. Dekker, 1993.

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1964-, McCulloch Iain, Shalaby Shalaby W, American Chemical Society. Division of Polymer Chemistry., and American Chemical Society Meeting, eds. Tailored polymeric materials for controlled delivery systems. American Chemical Society, 1998.

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Müller, Rainer H. Colloidal carriers for controlled drug delivery and targeting. CRC Press, 1990.

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Частини книг з теми "Controlled Drug Delivery System"

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Holowka, Eric P., and Sujata K. Bhatia. "Controlled-Release Systems." In Drug Delivery. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1998-7_2.

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Pillai, Akhilraj, Dhanashree Bhande, and Vinal Pardhi. "Controlled Drug Delivery System." In Studies in Mechanobiology, Tissue Engineering and Biomaterials. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-6564-9_11.

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Janapareddi, Krishnaveni, Bhaskara R. Jasti, and Xiaoling Li. "Evolution of Controlled Drug Delivery Systems." In Drug Delivery. John Wiley & Sons, Inc, 2016. http://dx.doi.org/10.1002/9781118833322.ch15.

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Jain, Surendra K., Aristide Laurel Mokale Kognou, Deepti Jain, Vinod Dhote, and Rajesh Singh Pawar. "Chemical Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_12.

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Kumar, Amit, Kashid Saurabh Machhindra, Keerti Jain, and Awesh K. Yadav. "Transdermal Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_5.

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Upadhyay, S., S. Soni, T. Shukla, et al. "Implantable Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_6.

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Sakagami, Masahiro, and Mark Gumbleton. "Targeted Drug Delivery Through the Respiratory System: Molecular Control on Lung Absorption and Disposition." In Controlled Pulmonary Drug Delivery. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-9745-6_6.

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Reza Rezaie, Hamid, Mohammadhossein Esnaashary, Abolfazl Aref arjmand, and Andreas Öchsner. "Controlled Drug Delivery Systems." In A Review of Biomaterials and Their Applications in Drug Delivery. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-0503-9_4.

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Urquhart, John. "The Therapeutic System: Therapeutic Implications of Rate-Controlled Drug Delivery." In Directed Drug Delivery. Humana Press, 1985. http://dx.doi.org/10.1007/978-1-4612-5186-6_4.

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Rossi, Filippo, Giuseppe Perale, and Maurizio Masi. "Overview on Polymeric Drug Delivery Systems." In Controlled Drug Delivery Systems. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-02288-8_3.

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Тези доповідей конференцій з теми "Controlled Drug Delivery System"

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Batista, Daniel V., and Marco S. Reis. "Balancing modelling complexity and experimental effort for conducting QbD on lipid nanoparticles (LNPs) systems." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.163183.

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The promising properties of lipid nanoparticles (LNPs) as drug carriers have been attracting significant attention in the field of drug delivery. However, further research is still required for a better understanding of their integration in the pharmaceutical industry. The Quality by Design (QbD) approach aims at ensuring the safety and efficiency in the development of new drugs, through an holistic, risk-based approach that gathers all sources of knowledge available about the system under analysis. One key resource of the QbD framework is the rich toolkit of Design of Experiments (DOE), to de
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Carigga Gutierrez, Nazareth M., Ahmed G. Abdelhamid, Amandine Hurbin, Anne-Laure Bulin, Jean-Luc Coll, and Mans Broekgaarden. "Applying photodynamics for radiotherapy-controlled drug delivery." In Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXIII, edited by David H. Kessel, Tayyaba Hasan, and Edward V. Maytin. SPIE, 2025. https://doi.org/10.1117/12.3040703.

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Maloney, John M. "An Implantable Microfabricated Drug Delivery System." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43186.

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We report on the development of a fully implantable drug delivery system capable of delivering hundreds of individual doses. This product is intended for the controlled release of potent therapeutic compounds that might otherwise require frequent injections. Our system has the following capabilities: • Stable, hermetic storage of therapeutic drugs in solid, liquid, or gel form; • Individual storage of discrete doses for multiple-drug regimens; • Wireless communication with an external controller for device monitoring and therapy modification; • Choice of preprogrammed release or release on com
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Blanco, Letia, Panos S. Shiakolas, Pranesh B. Aswath, et al. "A Thermoresponsive Hydrogel Based Controlled Drug Delivery Device." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-88564.

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Thermoresponsive hydrogels exhibit the unique property of volume change as a function of change in temperature as they transition between hydrophilic and hydrophobic states. These hydrogels can be loaded with drug/protein and serve as reservoirs for drug/protein delivery applications. A hydrogel based device for controlled drug delivery is designed with a number of subsystems that are interfaced with LabVIEW for development of a functional device. The device was designed using analytical and finite element analysis procedures and fabricated. In this manuscript, the device design will be review
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Demina, P. A., N. V. Sholina, R. A. Akasov, et al. "Multimodal upconversion nanoparticles with controlled drug release as drug delivery system." In 2020 International Conference Laser Optics (ICLO). IEEE, 2020. http://dx.doi.org/10.1109/iclo48556.2020.9285550.

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Divetia, Asheesh, Nolan Yoshimura, Guann-Pynn Li, Baruch D. Kuppermann, and Mark Bachman. "Controlled and Programmable Drug Delivery Using a Self-Powered MEMS Device." In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38054.

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Controlled and targeted drug delivery systems have gained a lot of interest as they offer numerous benefits such as precise dosing, reduced side-effects and increased patient compliance. We have designed a microelectromechanical systems (MEMS) drug delivery device that is capable of releasing drugs in a controlled and programmable manner. This self-powered device does not require any external stimulation or control to achieve pulsatile release of drugs. The device consists of multiple reservoirs containing the drug embedded together with a water-swellable polymer. The swelling of the polymer u
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Yu, Ruixia, Hualing Chen, Tianning Chen, and Hairong Wang. "Topology Optimization of MEMS-Based Biodegradable Controlled Drug Delivery System for Combination Therapy." In 2007 First International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2007. http://dx.doi.org/10.1115/mnc2007-21175.

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MEMS-based biodegradable controlled release system with micro multi-chambers can respectively enclose two drugs in different chambers to realize a combination therapy. In order to synchronously obtain the linear release of two drugs, it is necessary to completely investigate the topology optimization of the system. This paper introduces the theory of multi-objective topology optimization into MEMS-based biodegradable controlled release system for the combination therapy. Furthermore, a new method of CA-based evolutionary structural optimization (CA-ESO) is presented to accomplish the topology
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Ratnayake, W. R. A. P. J., J. W. Damunupola, S. Rajapakse, and A. C. A. Jayasundera. "Nanocellulose-Protein Matrices: A Model System for Controlled Drug Delivery." In International Conference on Nano Science and Nano Technology. The International Institute of Knowledge Management (TIIKM), 2018. http://dx.doi.org/10.17501/23861215.2018.5101.

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Wang, Xiaopeng, Tianning Chen, Zhanxiao Yang, and Wanjun Wang. "Design of controlled drug delivery system with optimal release characteristics." In MOEMS-MEMS 2006 Micro and Nanofabrication, edited by Ian Papautsky and Wanjun Wang. SPIE, 2006. http://dx.doi.org/10.1117/12.644077.

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Loh, Watson, and Fernanda Da Silveira Lima. "Liquid- crystalline dispersed systems for controlled drug delivery." In XXIII Congresso de Iniciação Científica da Unicamp. Galoá, 2015. http://dx.doi.org/10.19146/pibic-2015-38173.

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Звіти організацій з теми "Controlled Drug Delivery System"

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Sirivat, Anuvat. Electrically controlled release of drugs from alginate hydrogels for transdermal drug delivery application. Chulalongkorn University, 2014. https://doi.org/10.58837/chula.res.2014.80.

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A drug-loaded conductive polymer/hydrogel blend, benzoic acid-loaded poly(3,4-ethylenedioxythiophene/alginate (BA-loaded PEDOT/Alg) hydrogel, was used as a carrier/matrix for an electrical stimuli transdermal drug delivery system (TDDS). The effects of crosslinking ratio, PEDOT particle size, and electric field strength on the release mechanism and the diffusion coefficient (D) of BA were examined by using a modified Franz-diffusion cell. The diffusion scaling exponent value of BA is close to 0.5 which refers to the diffusion controlled mechanism, or the Fickian diffusion as the BA release mec
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2

Chutimaworapan, Suchada, Chaiyo Chaichantippayuth, and Areerat Laopaksa. Formulation of pharmaceutical products of Garcinia mangostana Linn. extracts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.32.

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Part I: The purpose of the investigation was to develop the extraction process that was simple, practical and giving high yield. The maceration of dried powder of Garcinia mangostana fruit husk with ethyl acetate gave yellow crystalline powder of mangostin. The yield was calculated as 7.47%. The identification of the Garcinia mangostanahusk extract was carried out by thin-layer chromatography (TLC) and differential scanning calorimetry. The TLC of mangostin was done by using the alumina sheet and ethyl acetate: hexane (3:1) as mobile phase. The Rf value as compared with standard mangostin was
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3

Shalaby, Shalaby W. Injectable Absorbable Ocular Inserts for Controlled Drug Delivery. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/adb229497.

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McPhillips, D. M., M. W. Price, J. W. Gibson, and R. A. Casper. Development of an On-Demand, Generic, Drug-Delivery System. Defense Technical Information Center, 1985. http://dx.doi.org/10.21236/ada158550.

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5

Pflugfelder Ghanashyam S., Stephen C. Broadly Applicable Nanowafer Drug Delivery System for Treating Eye Injuries. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada613401.

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Dash, Alekha K. Novel in Situ Gel Drug Delivery System for Breast Cancer Treatment. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada474685.

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7

Silva, João, Matheus Warmeling, and Rogério Pagnoncelli. Platelet-rich fibrin as a drug delivery system: a scoping review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.8.0004.

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8

Sledge, George W. Nanoparticle: Monoclonal Antibody Conjugates: A Novel Drug Delivery System in Human Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada420569.

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9

Sledge, George. Nanoparticle: Monoclonal Antibody Conjugates: A Novel Drug Delivery System in Human Breast Cancer. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada393348.

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Choi, Soojeong, Seoeun Oh, and Ildoo Chung. Synthesis and characterization of L-lysine polyurethane (LPU) nanoparticles for drug delivery system. Peeref, 2023. http://dx.doi.org/10.54985/peeref.2307p9824908.

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