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Готові списки джерел за темами / Controllo metabolico / Дисертації

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Дисертації з теми "Controllo metabolico"

Автор: Grafiati

Опубліковано: 11 березня 2023

Оновлено: 31 липня 2025

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1

Rodriguez, Rodriguez Mauricio. "Pyrimidine nucleotide de novo biosynthesis as a model of metabolic control." Texas A&M University, 2005. http://hdl.handle.net/1969.1/4425.

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This manuscript presents a thorough investigation and description of metabolic control dynamics in vivo and in silico using as a model de novo pyrimidine biosynthesis. Metabolic networks have been studied intensely for decades, helping develop a detailed understanding of the way cells carry out their biosynthetic and catabolic functions. Biochemical reactions have been defined, pathway structures have been proposed, networks of genetic control have been examined, and mechanisms of enzymatic activity and regulation have been elucidated. In parallel with these types of traditional biochemical an

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2

Murphy, Michelle. "A study of the contribution of minor GABA metabolites to the control of feeding in the rat." Thesis, University of Aberdeen, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322640.

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This project aimed to investigate the role of the γ-lactone of 3,4-dihydroxybutanoic acid (3,4DB) which was claimed by Japanese investigators to be one of several endogenous γ-lactones involved in the control of food intake. Tissue, plasma and urine organic acid profiles were screened for the γ-lactone of 3,4DB using both GC and GCMS. Careful mass spectral analysis and <I>in vitro</I> acid-γ-lactone exchange analyses with structural validation studies showed that the γ-lactone of 3,4DB did not occur <I>in vivo</I> but that the free acid of 3,4DB did. This rejects previous claims to the contrar

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3

Martins, Ricardo Alves. "Termorregulação e depressão metabólica em endotermos." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/3/3139/tde-13102009-154825/.

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A depressão metabólica em aves e mamíferos, dada a alta demanda energética destes animais, se apresenta, geralmente, como resposta às condições de escassez de alimentos e baixas temperaturas. Desta forma, este projeto busca explorar, no campo teórico, como o sistema de termorregulação poderia atuar no sentido de maximizar as reservas energéticas minimizando os gastos metabólicos (depressão metabólica). Para tanto, fazemos uso de teorias da engenharia de controle que propiciam ferramental teórico para analisar como se dariam essas minimizações, ou seja, como o sistema nervoso atuaria estabelece

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4

Baeza, Fernández Damian Francisco. "Diseño y simulación de un sistema para el control del estado metabolico de células animales en cultivo." Tesis, Universidad de Chile, 2012. http://www.repositorio.uchile.cl/handle/2250/111533.

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Magíster en Ciencias de la Ingeniería, Mención Química<br>Ingeniero Civil Químico<br>Resultados experimentales señalan que las células animales pueden alcanzar múltiples estados metabólicos con distintas razones de tasa de producción de lactato a tasa de consumo de glucosa (DL=DG), lográndose razones muy por debajo de la razón estequiométrica igual a 2 [mol=mol]. En el presente trabajo de tesis se planteó y ajustó un modelo metabólico que describe el metabolismo de un cultivo de control y se corroboró su falta de capacidad de alcanzar más de un estado estacionario a través de la comparación c

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5

Baptista, Antonio Sampaio. "Saccharomyces cerevisiae na redução de aflatoxicoses e o efeito na distribuição e na excreção da radioatividade de AFB13H em ratos." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/64/64132/tde-02022006-175649/.

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Para avaliar o efeito de diferentes linhagens de leveduras, Saccharomyces cerevisiae, vivas, na redução de aflatoxicoses e, contribuir para o entendimento do modo de ação destas leveduras sobre aflatoxina B1 marcada com trítio (AFB13H), foram conduzidos três experimentos. No primeiro experimento, foram utilizados ratos Wistar para investigar o efeito de duas linhagens de S. cerevisiae (Y1026 e Y904), e da suplementação com aminoácidos na redução de aflatoxicoses. O bioensaio, em delineamento inteiramente casualizado, foi conduzido por 28 dias para avaliar sete tratamentos (dietas), sendo um

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6

Thomas, Simon. "Computerised metabolic control analysis." Thesis, Oxford Brookes University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359794.

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7

Taylor, Scott. "Internal metabolic state and metabolic costs in human motor control." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/55145.

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The brain controls behaviour and has to manage the body’s resources (including energy) at the same time. How the brain coordinates and combines computations for controlling behaviour in response to metabolic state is little understood. I examined internal metabolic state and its role in motor coordination. I found that internal metabolic state modulates human motor coordination, with a lower energy expenditure associated with performing a velocity-controlled centre-out reaching task when in a low metabolic state. One approach to understanding human motor coordination is to consider motor cost

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8

Small, J. R. "Theoretical aspects of metabolic control." Thesis, Oxford Brookes University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382208.

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9

Duncan, John Andrew Carleton University Dissertation Biology. "Glycolytic enzyme binding and metabolic control." Ottawa, 1988.

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10

Kiwan, Alisar. "Controllo adrenergico del metabolismo glucidico in Anguilla anguilla." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amslaurea.unibo.it/3005/.

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Le conoscenze relative al controllo ormonale del metabolismo epatico dei pesci sono ancora piuttosto limitate e per molti anni sono state controverse. Per lungo tempo si è ritenuto che le catecolamine, adrenalina e noradrenalina, agissero nel fegato dei pesci soltanto attraverso i recettori adrenergici di tipo β. Quindi l’assetto recettoriale dei mammiferi, che comprende recettori α e β, era considerato frutto di un processo evolutivo che non aveva ancora avuto luogo nei pesci. Successivamente, nel fegato di vari teleostei è stata dimostrata la presenza di recettori sia α che β. Tuttavia il ru

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11

Armani, Andrea. "Transcription factor EB controls metabolic flexibility during exercise." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3422410.

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Skeletal muscle is the most abundant tissue in the whole organism representing more than 40% of the total body mass. This organ is responsible for the 30% of metabolic rate in basal condition, suggesting its great relevance not only for locomotor activity, but also for the control of whole body metabolism. Indeed skeletal muscle is a highly dynamic tissue that modulates its metabolism and mass as a consequence of different physiopathological conditions. One stimulus that triggers major adaptations is exercise, which is also well known to activate autophagy (Grumati, Coletto, Schiavinato, et al

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12

Locateli, Bruna Taiza. "Indução de resistência por agentes abióticos em soja à mosca-branca." Universidade Tecnológica Federal do Paraná, 2017. http://repositorio.utfpr.edu.br/jspui/handle/1/2677.

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A soja é uma das culturas mais antigas e praticadas no mundo, tendo sua importância pelo elevado teor de proteínas, sendo utilizada na alimentação humana e animal, além de ser o principal produto de exportação brasileira. Apesar da alta produção nacional, a cultura possui perdas de produtividade pelos ataques de insetos-pragas, dentre eles, a mosca-branca Bemisia tabaci Biótipo B (Hemiptera: Aleyrodidae). Seu controle tradicional é realizado com inseticidas, mas atualmente métodos alternativos estão sendo avaliados, considerando a não contaminação do ambiente e a saúde humana. O presente traba

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13

Sauro, H. M. "Control analysis and simulation of metabolism." Thesis, Oxford Brookes University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374977.

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14

Murray, Andrew James. "Control of cardiac metabolism and efficiency." Thesis, University of Oxford, 2003. http://ora.ox.ac.uk/objects/uuid:858cc1f9-7ba0-4999-a1c8-614a950888c2.

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15

Ainscow, Edward Keith. "Control and regulation of hepatocyte metabolism." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624775.

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16

Sampson, William James. "The intracellular control of cholesterol metabolism." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/26913.

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The liver has a major role in the metabolism of cholesterol, being the main site of lipoprotein assembly and degradation and the only tissue where the metabolism of cholesterol to bile acids occurs. This provides the major pathway for the removal of cholesterol from the body. The results described in this thesis concern the use of specific enzyme inhibitors (58-035, Azacholesterol, Mevinolin) to determine the intracellular use of different sources of cholesterol in monolayers of rat hepatocytes. In particular, the fates of newly synthesized cholesterol from mevalonic acid and cholesterol deriv

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17

Filho, JosÃ Ferreira da Cunha. "L-alanil-glutamina e seus efeitos sobre o estresse oxidativo, O controle glicÃmico e a resposta inflamatÃria em crianÃas Submetidas Ã palatoplastia." Universidade Federal do CearÃ, 2007. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=1588.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>A palatoplastia Ã o procedimento cirÃrgico que visa o fechamento da comunicaÃÃo das cavidades nasal e oral, resultante do nÃo fechamento dos processos palatinos embrionÃrios, na Ãpoca de formaÃÃo da face. O objetivo deste estudo foi avaliar o efeito da L-alanil-glutamina sobre o estresse oxidativo, o controle glicÃmico e a resposta inflamatÃria em pacientes portadores de fissuras lÃbio-palatais, submetidos Ã palatoplastia. O estudo foi prospectivo, simples cego, randomizado e controlado por placebo, sendo constituÃdo por 30 (t

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18

Müller, Mônica Anghinoni. "Influência de dinamizações de Mercurius solubilis em enzimas de defesa, crescimento da soja e no controle de Pratylenchus brachyurus." Universidade Estadual do Oeste do Paraná, 2015. http://tede.unioeste.br:8080/tede/handle/tede/1268.

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Made available in DSpace on 2017-07-10T17:37:02Z (GMT). No. of bitstreams: 1 Monica_Anghinoni_Muller.pdf: 756682 bytes, checksum: 61f5a661d3ee29d68326be6cb32f6bc7 (MD5) Previous issue date: 2015-02-20<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The nematode Pratylenchus brachyurus known as nematode lesions, affects the soybean crop caused significant damage, this means that there is a need to develop alternatives that supply the control of pathogens by aggregating in productivity. Then the objective is to verify the influence of homeopathic Mercurius solubilis in diff

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19

Feijo, Dubois Luiz Gustavo. "Metabolic control of the glioma stem cell behavior." Paris 6, 2013. http://www.theses.fr/2013PA066680.

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Glioblastomas (GBM) are the most frequent and aggressive tumors of the human central nervous system (CNS). Highly vascularized, infiltrating, and resistant to current therapies, they affect patients at different ages. The median survival of patients is shorter than 18 months. A growing body of evidence indicates that glioblastoma cancer stem-like cells (GSC) play a major role in the development of these tumors and their resistance to current therapies. Development of effective therapies requires understanding the molecular mechanisms that govern GSC properties, including the signals that susta

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20

Gardemann, Andreas, Gerhard Püschel, and Kurt Jungermann. "Nervous control of liver metabolism and hemodynamics." Universität Potsdam, 1992. http://opus.kobv.de/ubp/volltexte/2011/5134/.

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21

Heinz, Sabine. "Metabolite control of gene expression in cucumber." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302132.

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22

Janssens, Markus Peter-Erik. "Hormonal control of flight metabolism in Odonata?" Master's thesis, University of Cape Town, 1995. http://hdl.handle.net/11427/21424.

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Members of the AKHIRPCH family of peptides were identified in corpora cardiaca of the dragonfly Anax imperator (Anisoptera: Aeshnidae), Orthetrumjuliajalsum (Anisoptera: Libellulidae) and the damselflies Pseudagrion inconspicuum and Ischnura senegalensis (Zygoptera: Coenagrionidae). After isolation ofthe peptides by reversed phase high performance liquid chromatography, the primary structures were established by Edman sequencing and mass spectrometry (Ani-AKH: pGlu-Val-Asn-Phe-Ser-Pro-Ser-TrpNH 2 ), (Lia-AKH: pGlu-Val-Asn-Phe¬ Thr-Pro-Ser- TrpNH 2 ) and (Psi-AKH: pGlu- Val-Asn-Phe- Thr-Pro-Gly

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23

Regan, Lucy. "Metabolic pathway engineering of the toluene degradation pathway." Thesis, University College London (University of London), 1995. http://discovery.ucl.ac.uk/1317891/.

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This thesis addresses the problem of how to examine a metabolic pathway and identify what are the key elements, specifically with respect to rate-limitation. The aim is to be able to analyze a pathway, identify the bottlenecks and implement genetic modifications to remove these bottlenecks. This is done by defining the system of interest and developing a predictive model using kinetic data. The model predictions can then be verified using fermentation data and genetic techniques to make the appropriate changes for improved performance. The test system chosen for this study was the TOL meta-cle

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24

Reglin, Bettina, Timothy W. Secomb, and Axel R. Pries. "Structural Control of Microvessel Diameters: Origins of Metabolic Signals." FRONTIERS MEDIA SA, 2017. http://hdl.handle.net/10150/626059.

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Diameters of microvessels undergo continuous structural adaptation in response to hemodynamic and metabolic stimuli. To ensure adequate flow distribution, metabolic responses are needed to increase diameters of vessels feeding poorly perfused regions. Possible modes of metabolic control include release of signaling substances from vessel walls, from the supplied tissue and from red blood cells (RBC). Here, a theoretical model was used to compare the abilities of these metabolic control modes to provide adequate tissue oxygenation, and to generate blood flow velocities in agreement with experim

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25

Dunphy, Andrea Maria. "Hepatic adrenergic mechanisms and the metabolic control of lactation." Thesis, University of Surrey, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306862.

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26

Acerenza, Luis. "Studies on the control of time-dependent metabolic processes." Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/14242.

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Sensitivity analysis studies how changes in the parameters affect the system's variables. Its application to metabolic systems (Metabolic Control Analysis, MCA) was traditionally developed under certain assumptions:i) the steady state is stable (the effect on the steady state values only is studied).ii) each reaction is catalyzed by one enzyme, the rates being proportional to the corresponding enzyme concentration.iii) the parameters are changed by a small (strictly speaking infinitesimal) amount. In the present work MCA is extended to deal with the instantaneous values of time-dependent metab

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27

Kim, Jin Young Leo. "METABOLIC CONTROL OF THE EPIGENOME IN GLIOBLASTOMA STEM CELLS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case157616602610095.

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28

Sorrentino, Giovanni. "Metabolic control of YAP/TAZ by the Mevalonate Pathway." Doctoral thesis, Università degli studi di Trieste, 2014. http://hdl.handle.net/10077/10119.

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2012/2013<br>The YAP and TAZ mediators of the Hippo pathway (hereafter called YAP/TAZ) promote tissue proliferation and organ growth. However, how their biological properties intersect with cellular metabolism remains unexplained. Here, we show that YAP/TAZ activity is controlled by the SREBP/mevalonate pathway. Inhibition of the rate-limiting enzyme of this pathway (HMG-CoA reductase) by statins opposes YAP/TAZ nuclear localization and transcriptional responses. Mechanistically, the geranylgeranyl pyrophosphate produced by the mevalonate cascade is required for activation of Rho GTPases t

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29

Ulfhielm, Erik. "Modeling of metabolic insulin signaling in adipocytes." Thesis, Linköping University, Department of Electrical Engineering, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-6520.

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<p>Active insulin receptors (IR) phosphorylate insulin receptor substrate (IRS), but it is not clear whether IRS is phosphorylated mainly by IR at the plasma membrane or by internalized IR in the cytosol. In this thesis, structural identifiability analysis and parameter sensitivity analysis is performed for models of the first steps in the metabolic insulin signaling pathway. In particular, the identifiability of the kinetic parameters governing IRS phosphorylation are investigated.</p><p>Given measurements of the relative increase in phosphorylation degree of IR and IRS, the structural ident

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30

Sani, Halimah Abdullah. "Mechanisms of control of lipoprotein lipase." Thesis, University of Newcastle Upon Tyne, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386912.

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31

Maksai, Tibor. "Modeling Anaerobic Muscle Metabolism." Thesis, Linköping University, Department of Mathematics, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11427.

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<p>Is it possible for a minimal model of anaerobic muscle contraction to describe measured data? There have been many models trying to describe separate parts of the human body with various results. In this thesis a model has been created to describe all the essential biochemical reactions of anaerobic muscle metabolism during contraction but with as few states and parameters as possible. A toolbox in Matlab was used for simulation and also for parameter estimation. The best model eventually got validated to see statistically how well it can describe the measured data. During the simulations a

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32

Brandt, Karsten. "Fat metabolism and the control of food intake." Hamburg Kovač, 2006. http://www.verlagdrkovac.de/3-8300-2648-X.htm.

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33

Mos, Magdalena. "The control of nitrogen metabolism in Aspergillus nidulans." Thesis, University of Liverpool, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539565.

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34

Pittner, R. A. "Studies on the control of hepatic glycerolipid metabolism." Thesis, University of Nottingham, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356536.

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35

Johnson, Andrew William. "Metabolic control of energetics in human heart and skeletal muscle." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:82c0dce6-a162-4c08-b061-3ea7f2e35134.

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Myocardial and skeletal muscle high energy phosphate metabolism is abnormal in heart failure, but the pathophysiology is not understood. Plasma non-esterified fatty acids (NEFA) increase in heart failure due to increased sympathetic drive, and regulate the transcription of mitochondrial uncoupling protein-3 (UCP3), through peroxisome proliferator-activated receptor-α. The aim of the work in this thesis was to determine whether cardiac PCr/ATP ratios and skeletal muscle PCr kinetics during exercise were related to cardiac and skeletal muscle UCP3 levels respectively, thus providing a mechanism

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36

Gray, Jennifer A. "Biotin biosynthetic enzymes and the metabolic control of biotin biosynthesis." [Ames, Iowa : Iowa State University], 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1473213.

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37

Colamatteo, Alessandra. "Metabolic control of FoxP3 expression in human regulatory T cells." Doctoral thesis, Universita degli studi di Salerno, 2017. http://hdl.handle.net/10556/2686.

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2015 - 2016<br>Regulatory CD4+CD25+ T (Treg) cells play a central role in the maintenance of immune self-tolerance and homeostasis. Although Treg cells operate through multiple mechanisms, it appears that the expression of the transcription factor Forkhead-box-P3 (FoxP3) is crucial for their function. Here we describe human peripheral Treg (pTreg) cells that develop from CD4+CD25- T (Tconv) cells following suboptimal stimulation via the T cell antigen receptor (TCR). This population of pTreg cells, which we call inducible Treg (iTreg) cells, is characterized by high FoxP3 expression, strong su

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38

Passaretti, Federica. "Molecular pathways involved in metabolic control of CCL5 in adipocytes." Doctoral thesis, Universita degli studi di Salerno, 2014. http://hdl.handle.net/10556/1468.

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2012 - 2013<br>Obesity is a chronic disorder characterized by a tonic low-grade activation of the innate immune system that affects steady-state measures of metabolic homeostasis over time. In addition, obesity is often accompanied by elevations in tissue and circulating FFA concentrations. Systemic levels of FFAs can induce inflammatory cascades in adipocytes and macrophages through TLR4-dependent effect. Signaling through TLR4 activates a broad range of intracellular cascades that include stimulation of IKK-β, NF-kB, JNK and AP1. Indeed, in addition to store excess calories in the for

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39

CHIU, MARTINA. "A METABOLIC APPROACH FOR THE CONTROL OF GLUTAMINE DEPENDENT TUMORS." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/231095.

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Introduzione. Le alterazioni metaboliche sono una caratteristica delle cellule tumorali, le quali devono sostenere un’attiva proliferazione senza incorrere in una carenza energetica. Pertanto, la ricerca di approcci metabolici che interferiscono con la crescita tumorale è attivamente perseguita. La maggior parte delle cellule tumorali è contraddistinta da un aumentato consumo di glucosio, necessario per rifornire il ciclo di Krebs di intermedi estratti a scopo biosintetico (anaplerosi). Tuttavia, a seconda delle mutazioni oncogeniche presenti nel fenotipo tumorale, altri nutrienti oltre al glu

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40

Charest-Marcotte, Alexis 1984. "Functional interaction between PROX1, ERR[alpha] and PGC-1[alpha] in the control of energy metabolism." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111571.

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Nuclear receptors play crucial roles in the transcriptional regulation of many biological processes such as development and cellular differentiation. ERRalpha is known, along with coactivator PGC-1alpha, to playa central role in the control of energy metabolism in cardiac and skeletal muscle. They activate the expression of many genes involved in mitochondrial oxidative metabolism. Here we identified PROX1, a factor that was previously shown to broadly influence metabolism, as a regulator of this pathway. Indeed, PROX1 interacts in vitro and in vivo with both ERRalpha and PGC-1alpha. To provid

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Carlos, Daniele Maria de Oliveira. "Impacto da variabilidade de peso no controle mateb?lico de pacientes transplantados card?acos." Universidade Federal do Rio Grande do Norte, 2009. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13285.

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Made available in DSpace on 2014-12-17T14:13:45Z (GMT). No. of bitstreams: 1 CarlosDMO_DISSERT.pdf: 3393165 bytes, checksum: 8775fe07131b0869171353c32e39624c (MD5) Previous issue date: 2009-11-27<br>Heart transplantation (HT) represents one of the greatest advances in medicine over the last decades. It is indicated for patients with severe heart disease unresponsive to clinical treatment and conventional surgery, poor short-term prognosis and a 1- year mortality rate over 40%. HT has improved survival worldwide (80% in the first year, 70% in five years and 60% in ten years). However, the pro

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42

Godwin, Bryan. "Discrete sliding mode control of drug infusions." Thesis, Georgia Institute of Technology, 1991. http://hdl.handle.net/1853/16806.

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Hawkey, Robin Keith. "Amino acid oxidation and protein metabolism in animals." Thesis, University of Nottingham, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334760.

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Oliveira, Camila Victória Sousa. "Avaliação do papel do ferro e de proteínas envolvidas em seu metabolismo na infecção in vitro de macrófagos por Leishmania amazonensis ou Leishmania major." reponame:Repositório Institucional da FIOCRUZ, 2015. http://www.arca.fiocruz.br/handle/icict/15216.

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Submitted by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2016-08-09T19:14:17Z No. of bitstreams: 1 Camila Victória Sousa Oliveira Avaliaçao do papel... 2015.pdf: 3464299 bytes, checksum: ca91c962ae5b021bf250ea2db05e1dd6 (MD5)<br>Approved for entry into archive by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2016-08-09T19:21:45Z (GMT) No. of bitstreams: 1 Camila Victória Sousa Oliveira Avaliaçao do papel... 2015.pdf: 3464299 bytes, checksum: ca91c962ae5b021bf250ea2db05e1dd6 (MD5)<br>Made available in DSpace on 2016-08-09T19:21:45Z (GMT). No. of bitstreams: 1 Camila

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Coupland, Karen J. "The effects of a family-based intervention on regimen adherence and metabolic control of adolescents with IDDM: A randomized controlled outcome study." Thesis, University of Ottawa (Canada), 1990. http://hdl.handle.net/10393/5921.

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Patients with insulin-dependent diabetes mellitus (IDDM) must adhere to a complex treatment regimen. Adherence is often poor during adolescence, when the regimen behaviours may interact negatively with many of the developmental tasks. In a randomized controlled outcome study, 15 adolescents and their families participated in a family-based intervention for improving adherence to the diabetic regimen. Fourteen comparison group adolescents with IDDM spent a comparable amount of time learning stress management techniques. Adolescents in both groups attended a diabetes management review session wi

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46

Alemany, Agulló Jaume. "Caracterització de metabòlits produïts per soques de "Pseudomonas fluorescens" efectives en el control biològic de fongs fitopatògens." Doctoral thesis, Universitat de Girona, 2001. http://hdl.handle.net/10803/7774.

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El principal objectiu d'aquest treball ha estat estudiar la producció de metabòlits amb activitat antibiòtica per soques de l'espècie Pseudomonas fluorescens de la col·lecció EPS, i també avaluar la seva potencialitat com a agents de biocontrol. Es va disposar també de diverses soques de P. fluorescens, cedides per altres investigadors, que van utilitzar-se com a referència perquè algunes són actives en control biològic i produeixen metabòlits secundaris d'interès en el biocontrol de malalties de plantes.<br/>La present memòria s'estructura en cinc capítols, que són, introducció al control bio

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Parry, Sion A. "Metabolic responses to short-term high-fat overfeeding." Thesis, Loughborough University, 2017. https://dspace.lboro.ac.uk/2134/26916.

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The main aim of this thesis was to increase our understanding of the metabolic responses associated with short-term high-fat overfeeding. To this end, four separate studies are described in this thesis; each of which involved the provision of a high-fat, high-energy diet to young, healthy, lean individuals. The first of these experimental chapters (Chapter 2) determined the effects of a 7-day, high-fat (65%), high-energy (+50%) diet on postprandial metabolic and endocrine responses to a mixed meal challenge. This chapter demonstrates that 7-days of overfeeding impaired glycaemic control in our

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Abdelrahman, Mohamed. "The association of periodontal disease with metabolic control in type 1 diabetic adolescents." University of Western Cape, 2020. http://hdl.handle.net/11394/8062.

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Magister Chirurgiae Dentium (MChD)<br>Chronic inflammation of the periodontium is known as periodontal disease. The inflammation can be contained only within gingival connective tissue or can progress, leading to the loss of gingival connective tissue and alveolar bone. Lately, periodontal disease is considered as a co-morbidity of diabetes mellitus (Polak, Sanui et al., 2020). Though studies that have assessed the relationship of periodontal status with the glycemic control in type 1 diabetes mellitus adolescents, such studies have not been conducted in South Africa.

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49

Fabregat, Rossell Andreu 1986. "Re-exploring testosterone metabolism : new insights for doping control." Doctoral thesis, Universitat Pompeu Fabra, 2014. http://hdl.handle.net/10803/289784.

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The detection of endogenous anabolic androgenic steroids (EAAS) is one of the most difficult analytical challenges in the doping control field. The main problem for their detection is to distinguish between normally endogenous concentrations and those observed after the exogenous administration of an EAAS. The screening methods for EAAS are currently based on the determination of the steroid profile and the application of the athlete biological passport. The inclusion of new steroid metabolites can improve the screening capabilities of the steroid profile. Thus, the objective of the thesis is

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50

O'Dea, Ellen Louise. "Homeostatic control of IkappaB metabolism determines NF-kappaB responsiveness." Diss., [La Jolla] : University of California, San Diego, 2010. http://wwwlib.umi.com/cr/ucsd/fullcit?p3403395.

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Thesis (Ph. D.)--University of California, San Diego, 2010.<br>Title from first page of PDF file (viewed May 28, 2010). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (leaves 142-151).

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