Добірка наукової літератури з теми "Cycling"

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Статті в журналах з теми "Cycling"

1

Buchkovich, K. J., and E. B. Ziff. "Nerve growth factor regulates the expression and activity of p33cdk2 and p34cdc2 kinases in PC12 pheochromocytoma cells." Molecular Biology of the Cell 5, no. 11 (1994): 1225–41. http://dx.doi.org/10.1091/mbc.5.11.1225.

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In the absence of serum, nerve growth factor (NGF) promotes the survival and differentiation of the PC12 pheochromocytoma cell line. In the presence of serum, NGF acts primarily as a differentiation factor and negative regulator of cell cycling. To investigate NGF control of cell cycling, we have analyzed the regulation of cyclin dependent kinases during PC12 cell differentiation. NGF treatment leads to a reduction in the steady-state protein levels of p33cdk2 and p34cdc2, two key regulators of cell cycle progression. The decrease in p33cdk2 and p34cdc2 coincides with a decrease in the enzymat
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2

Traganos, Frank. "Cycling without Cyclins." Cell Cycle 3, no. 1 (2004): 31–33. http://dx.doi.org/10.4161/cc.3.1.608.

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Holding, Cathy. "Cycling without cyclins." Genome Biology 5 (2004): spotlight—20040824–01. http://dx.doi.org/10.1186/gb-spotlight-20040824-01.

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Diehl, J. Alan. "Cycling to Cancer with Cyclin D1." Cancer Biology & Therapy 1, no. 3 (2002): 226–31. http://dx.doi.org/10.4161/cbt.72.

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Resnitzky, D., M. Gossen, H. Bujard, and S. I. Reed. "Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system." Molecular and Cellular Biology 14, no. 3 (1994): 1669–79. http://dx.doi.org/10.1128/mcb.14.3.1669-1679.1994.

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Conditional overexpression of human cyclins B1, D1, and E was accomplished by using a synthetic cDNA expression system based on the Escherichia coli tetracycline repressor. After induction of these cyclins in asynchronous Rat-1 fibroblasts, a decrease in the length of the G1 interval was observed for cyclins D1 and E, consistent with an acceleration of the G1/S phase transition. We observed, in addition, a compensatory lengthening of S phase and G2 so that the mean cell cycle length in populations constitutively expressing these cyclins was unchanged relative to those of their uninduced counte
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Resnitzky, D., M. Gossen, H. Bujard, and S. I. Reed. "Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system." Molecular and Cellular Biology 14, no. 3 (1994): 1669–79. http://dx.doi.org/10.1128/mcb.14.3.1669.

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Conditional overexpression of human cyclins B1, D1, and E was accomplished by using a synthetic cDNA expression system based on the Escherichia coli tetracycline repressor. After induction of these cyclins in asynchronous Rat-1 fibroblasts, a decrease in the length of the G1 interval was observed for cyclins D1 and E, consistent with an acceleration of the G1/S phase transition. We observed, in addition, a compensatory lengthening of S phase and G2 so that the mean cell cycle length in populations constitutively expressing these cyclins was unchanged relative to those of their uninduced counte
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7

Ježek, Jan, Daniel G. J. Smethurst, David C. Stieg, et al. "Cyclin C: The Story of a Non-Cycling Cyclin." Biology 8, no. 1 (2019): 3. http://dx.doi.org/10.3390/biology8010003.

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The class I cyclin family is a well-studied group of structurally conserved proteins that interact with their associated cyclin-dependent kinases (Cdks) to regulate different stages of cell cycle progression depending on their oscillating expression levels. However, the role of class II cyclins, which primarily act as transcription factors and whose expression remains constant throughout the cell cycle, is less well understood. As a classic example of a transcriptional cyclin, cyclin C forms a regulatory sub-complex with its partner kinase Cdk8 and two accessory subunits Med12 and Med13 called
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Yi, Xie, and Li Bing. "The Transcription Express Characteristics of Several Genes in the Process of Bombyx mori Ovarian Carcinoma." Advanced Materials Research 796 (September 2013): 39–42. http://dx.doi.org/10.4028/www.scientific.net/amr.796.39.

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Bombyx mori cell line (BmN) comes fromBombyx moriovary cell subculture. In order to study the change of several genes transcription in the process ofBombyx moriovary cells primary culture and subculture, we usedBombyx moriovary organizations and BmN cell lines as research materials, used Real Time fluorescent quantitative RT-PCR to detect cyclin gene family (CyclinA, CyclinB, CyclinB3, CyclinE, CyclinL1), p53 and Telomerase genes transcription level in the ovary and BmN cell lines, and took Actin3 gene as reference to dispose the results. The results showed that in theBombyx moriBmN cell lines
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Ehrhardt, Harald, Catarina Castro Alves, Franziska Wachter, and Irmela Jeremias. "TRAIL Preferentially Affects Cell Cycle-Arrested Tumor Cells Including Stem- and Progenitor Cells From Patients with Acute Lymphoblastic Leukemia." Blood 120, no. 21 (2012): 1879. http://dx.doi.org/10.1182/blood.v120.21.1879.1879.

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Abstract Abstract 1879 Leukemic stem- and progenitor cells exhibit low cycling activity which might represent a major cause for their increased treatment resistance. TRAIL (TNF-related apoptosis inducing ligand) is a novel putative anticancer drug currently in phase I and II clinical testing. We recently showed that TRAIL is able to address stem- and progenitor cells from patients with acute lymphoblastic leukemia (ALL) in xenotransplantation assays (Alves et al., Blood 2012,119,4224). As stem- and progenitor cells are often non-cycling, we asked here, whether TRAIL is able to address resting
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Cogswell, J. P., M. M. Godlevski, M. Bonham, J. Bisi, and L. Babiss. "Upstream stimulatory factor regulates expression of the cell cycle-dependent cyclin B1 gene promoter." Molecular and Cellular Biology 15, no. 5 (1995): 2782–90. http://dx.doi.org/10.1128/mcb.15.5.2782.

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Progression through the somatic cell cycle requires the temporal regulation of cyclin gene expression and cyclin protein turnover. One of the best-characterized examples of this regulation is seen for the B-type cyclins. These cyclins and their catalytic component, cdc2, have been shown to mediate both the entry into and maintenance of mitosis. The cyclin B1 gene has been shown to be expressed between the late S and G2 phases of the cell cycle, while the protein is degraded specifically at interphase via ubiquitination. To understand the molecular basis for transcriptional regulation of the cy
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Дисертації з теми "Cycling"

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Intravaia, Paul Joseph. "Cycling." OpenSIUC, 2014. https://opensiuc.lib.siu.edu/theses/1509.

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Merger, Alexis Nicole. "Life Cycling: Cardiovascular Benefits of Cycling for Women." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/579421.

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Cardiovascular disease is the leading killer of both men and women in the United States. Though prevalent in both genders, certain risk factors leave women especially susceptible to cardiovascular disease. Aerobic exercise has been shown to both prevent and control major risk factors. Through public awareness and outreach, women within the community will have the opportunity to learn about their risks and begin steps towards a healthier lifestyle. This paper will inform the average reader about the anatomy and physiology of the cardiovascular system, the risk factors associated with cardiovas
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Silva, Alexandre Manuel Oliveira da. "Cycling cities." Master's thesis, Universidade de Lisboa, Faculdade de Arquitetura, 2019. http://hdl.handle.net/10400.5/19235.

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Dissertação de Mestrado Integrado em Arquitetura, com a especialização em Urbanismo apresentada na Faculdade de Arquitetura da Universidade de Lisboa para obtenção do grau de Mestre.<br>A presente investigação centra-se na temática de promoção da mobilidade ciclável e a devida integração com os transportes ferroviários, tendo em consideração a orografia do terreno. Num momento em que a procura por soluções sustentáveis no âmbito da mobilidade em cidade tem vindo a crescer, constata-se que a mobilidade com recurso à bicicleta nas deslocações diárias poderá atenuar as dificuldades existentes, po
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Roop, Adrian Heston. "THE ANTHROPOLOGY OF CYCLING: AN ETHNOGRAPHIC DETAIL OF CYCLING'S EXPERIENCE." OpenSIUC, 2010. https://opensiuc.lib.siu.edu/theses/319.

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Competitive cycling is a sport that is popular around the world. My thesis explores the relationship between cyclesport and society. I begin my thesis with an introduction to the topic of cycling and how I will elucidate cycling's relationship within the sense of how cycle racing engages the nexus between the environment and subject in and through language use, embodiment, and practice. I then explain the methods that I use. Phenomenology, lived experience research, embodied performance, and language use. I utilized my experiences in different cycling communities and interviews to gain ac
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Reilly, Lyle. "City centered cycling." AUT University, 2009. http://hdl.handle.net/10292/895.

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This project explores design considerations and processes involved in the development of sports performance clothing specifically aimed at city cycling commuters. Research with a focus on smart clothing and electronic integration was used to form a technical framework in which the requirements of the end user were addressed. The result being the creation of a wearable electronic jacket containing a lighting system aimed at improving safety and comfort aspects affecting cycle commuters. The project methodology was essentially practice based with a strong experimental approach linked to the phys
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Springer, Alexander D. "Optimizing cycling power." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/105573.

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Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2016.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (page 29).<br>In this study we determine a viable bioenergetic model for power allocation during a cycling race. Various models have been proposed to address power allocation in races with two models rising above others: the Morton-Margaria Three Tank mod
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Kaewpanukrangsi, Nuanphan. "Creative-Up-Cycling." Thesis, Malmö högskola, Fakulteten för kultur och samhälle (KS), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-21543.

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The project elaborates design opportunities for a future practice that could promotealternative sustainable lifestyles on waste handling through up-cycling activities. It doesthis on a small scale through engagement in the local communities of the Hildaneighborhood and Segepark students’ accommodations in Sweden. To thesecommunities, creative-up-cycling is explored which it introduced here as an approachwhere neighbors can participate in making new things from leftover materials. Throughthis work creative-up-cycling is a proposed recommendation for a possible service systemon how to share the
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Underwood, Lindsey. "Aerodynamics of Track Cycling." Thesis, University of Canterbury. Mechanical Engineering, 2012. http://hdl.handle.net/10092/7804.

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The aim of this thesis was to identify ways in which the velocity of a track cyclist could be increased, primarily through the reduction of aerodynamic drag, and to determine which factors had the most significant impact on athlete performance. An appropriate test method was set up in the wind tunnel at the University of Canterbury to measure the aerodynamic drag of different cycling positions and equipment, including helmets, skinsuits, frames and wheels, in order to measure the impact of specific changes on athlete performance. A mathematical model of the Individual Pursuit (IP) event was
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Stone, Michael H., Margaret E. Stone, and William A. Sands. "Cycling Your Periodization Plan." Digital Commons @ East Tennessee State University, 2008. https://dc.etsu.edu/etsu-works/4674.

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Smith, Jimmy C. "The Effect of Seat Back Angle on Responses During Recumbent Cycling." Thesis, University of North Texas, 1990. https://digital.library.unt.edu/ark:/67531/metadc332582/.

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The purpose of this study was to evaluate metabolic, cardiorespiratory, and perceptual responses during recumbent cycle ergometry performed at various seat back angles and different work rates. Healthy college-aged men performed steady-state exercise at two work rates, 100 watts (n=46) and 150 watts (n=26), using five back seat angles, 90, 105, 120, 135, and 150 degrees. The results of this study suggest that recumbent seat back angles of 135 to 150 degrees are associated with lower metabolic and cardiorespiratory stress during rest and submaximal exercise than more upright positions. The redu
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Книги з теми "Cycling"

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Garrett, Greg. Cycling. Kensington Books, 2003.

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Mason, Paul. Cycling. Franklin Watts, 2011.

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North, David. Cycling. Flame Tree, 2011.

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Bow, James. Cycling. Franklin Watts, 2013.

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Gifford, Clive. Cycling. Franklin Watts, 2012.

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Currie, Stephen. Cycling. Lucent Books, 2014.

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Jenkins, George H. Cycling. Rourke Corp., 1994.

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Bailey, Donna. Cycling. Steck-Vaughn Library, 1991.

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Paul, Mason. Cycling. Sea-to-Sea Publications, 2010.

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10

Bow, James. Cycling. Franklin Watts, 2009.

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Частини книг з теми "Cycling"

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Cox, Peter. "Introduction." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-1.

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Cox, Peter. "Riding the city." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-10.

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Cox, Peter. "Towards a sociology of cycles and cycling." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-2.

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Cox, Peter. "Researching cycling." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-3.

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Cox, Peter. "Materials." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-4.

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Cox, Peter. "Environments." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-5.

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Cox, Peter. "Exploring (im)material space." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-6.

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Cox, Peter. "Competencies." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-7.

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Cox, Peter. "Riding together." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-8.

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Cox, Peter. "Meanings, representations and identities." In Cycling. Routledge, 2019. http://dx.doi.org/10.4324/9781315533698-9.

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Тези доповідей конференцій з теми "Cycling"

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Bruss, Lennart, and Anja Müller. "Urban Cycling and Automated Vehicles." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.474.

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Eggermond, Michael A. B. van, Dorothea Schaffner, and Nora Studert. "Assessing cycling skills in Switzerland." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.497.

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Gaster, Kristina, and Tina Gebiert. "Mileage-based accident risks of pedelec riders." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.416.

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Francke, Angela, Paul Papendieck, Lisa-Marie Schaefer, and Juliane Anke. "Perceived cycling safety during Corona times - Results of a longitudinal study in Germany." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.446.

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Oyoo, Robert O., and S. K. Mwea. "Challenges and Opportunities in Cycling Safety in Nairobi City, Kenya." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.451.

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Tumakova, Yana, Constant Cap, Azeb T. Legese, Marie Klosterkamp, and Angela Francke. "“The missing lights of Nairobi” - Cyclists' Perceptions of safety by cycling after-dark in Nairobi, Kenya." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.448.

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Shah, Nitesh R., and Christopher R. Cherry. "Riding an e-scooter at nighttime is more dangerous than at daytime." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.436.

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Ramírez-Leuro, Laura D., and Lenin A. Bulla-Cruz. "Cyclists' Safety and Security Multiple Correspondence Analysis from GPS Records for Route Choice in Bogotá - Colombia." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.447.

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Rubie, Elisabeth, Narelle Haworth, and Naohide Yamamoto. "Passing distance, speed and perceived risks to the cyclist and driver in passing events." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.439.

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Legese, Azeb T., Abhimanyu Prakash, Angela Francke, Yana Tumakova, Marie Klosterkamp, and Paul Papendieck. "More than a billion motives to focus on NMT Africa - Enhancing the quality of infrastructure to improve cycling safety and cycling culture in Africa, case in Ethiopia." In International Cycling Safety Conference. Technische Universität Dresden, 2022. http://dx.doi.org/10.25368/2022.450.

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Звіти організацій з теми "Cycling"

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Lißner, Sven, Stefan Huber, and Maike von Harten. Influence of the cycling campaign CITY CYCLING on cycling behaviour in Germany. TU Dresden, Fakultät Verkehrswissenschaften 'Friedrich List', 2023. http://dx.doi.org/10.26128/2023.65.

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The CITY CYCLING (STADTRADELN) campaign has been running since 2008 to motivate German citizens to use the bicycle for daily mobility routines. In the course of the MOVEBIS research project, nationwide GPS data of the CITY CYCLING participants were collected in the years 2018-2020 and were processed for planning purposes. This contribution addresses the question to which extent the participants in the CITY CYCLING campaign represent cyclists in the Federal Republic of Germany and whether the motivation during the campaign leads to a significant change in mobility behaviour. For this purpose, m
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JI, June HyeonJeong. Cycling with fireflies. Iowa State University, Digital Repository, 2015. http://dx.doi.org/10.31274/itaa_proceedings-180814-1282.

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Peter A. Pryfogle. Nutrient Cycling Study. Office of Scientific and Technical Information (OSTI), 2005. http://dx.doi.org/10.2172/966178.

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Peggs, Stephen, and Michael Furey. Rapid Cycling Medical Synchrotron. Office of Scientific and Technical Information (OSTI), 2007. http://dx.doi.org/10.2172/973828.

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Kumar, Nikil, Philip Besuner, Steven Lefton, Dwight Agan, and Douglas Hilleman. Power Plant Cycling Costs. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1046269.

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Krantz, F. M., and M. W. Richter. Mission/Maintenance/Cycling Effects on Reliability. Defense Technical Information Center, 1991. http://dx.doi.org/10.21236/ada251921.

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Morgenstern, Mark R. EPM 2482 Power Cycling Evaluation Summary. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada512571.

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Wall, T. S., P. R. Valenzuela, and C. Sue. Ultrafast Thermal Cycling of Solar Panels. Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/ada351580.

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Das, K. C., Adams, T. Thomas, Mark A. Eiteman, James R. Kastner, Sudhagar Mani, and Ryan Adolphson. Biorefinery and Carbon Cycling Research Project. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1053782.

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Koehn, Silas, Luca Oggiano, Kai Schaffarczyk, and Alois Peter Schaffarczyk. Aerodynamical benefits by optimizing cycling posture. Purdue University, 2022. http://dx.doi.org/10.5703/1288284317528.

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