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1

Nuriddinovna, INDIAMINOVA Gavkhar. "The Likelihood of Developing Periodontal Disease in Patients with Cardiovascular Diseases." American Journal Of Social Sciences And Humanity Research 5, no. 5 (2025): 131–34. https://doi.org/10.37547/ajsshr/volume05issue05-31.

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Анотація:
Currently, the forecast of the development of pathology is an important part of all branches of healthcare. [3,4,5]. However, despite the importance and scientific and practical significance of forecasting in dentistry, at present we have not found information about predictive models of individual risk of developing periodontitis in patients with hypertension.
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2

Walter, Michael A., and Peter N. Goodfellow. "Disease and development." Nature 355, no. 6361 (1992): 590–91. http://dx.doi.org/10.1038/355590a0.

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3

Sobue, Gen. "Development of disease-modifying therapy for neurodegenerative diseases." Rinsho Shinkeigaku 51, no. 11 (2011): 821–24. http://dx.doi.org/10.5692/clinicalneurol.51.821.

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4

Guo, Dugang, Jun Liu, and Xuewei Wang. "On development of multi-resolution detector for tomato disease diagnosis." Journal of Intelligent & Fuzzy Systems 41, no. 6 (2021): 6461–71. http://dx.doi.org/10.3233/jifs-210262.

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Plant disease is one of the major threats to food security. Accurate diagnosis of plant diseases can benefit the agricultural production. For the purpose of real-time plant disease diagnostics, the deep learning models are employed. In this study, we present an accurate identification method for common diseases of tomatoes based on deep-learning methods. The devising of multi-resolution detector, in line with bounding box generating and assigning, facilitates the feature extracting process of detection. The employment of an dropout and ADAMW (Adaptive moment estimation with decoupled weight de
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5

Irami, Araujo-Filho, Dantas Freire Artur, Araujo-Neto Irami, et al. "Kikuchi-Fujimoto disease: case report and review." International Journal of Medical Reviews and Case Reports 1, no. 1 (2017): 6–10. https://doi.org/10.5455/IJMRCR.kikuchi-fujimoto-disease.

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Анотація:
OBJECTIVE: The development of associated febrile to lymphadenomegaly leads to several diagnostic hypotheses, among them the Kikushi-Fujimoto disease. METHOD: This review was set up by searching PubMed/Medline, Web of Science and Scopus database using the following key words: "Kikushi disease", "Kikuchi-Fujimoto disease", "histiocytic necrotizing", "lymphadenitis", "lymphadenopathy". RESULTS: We report a case in a young patient with a fever associated with the emergence of adenomegalies and weight loss in two months, associated with hepatospleno
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6

Bankina, B. "Tan spot development peculiarities in Latvia." Plant Protection Science 38, SI 2 - 6th Conf EFPP 2002 (2017): 381–83. http://dx.doi.org/10.17221/10497-pps.

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Анотація:
Tan spot, caused by Pyrenophora tritici-repentis (Died.) Drechs., anamorph Drechslera tritici-repentis is one of the most important wheat diseases in the world, especially in the regions of intensive wheat growing. Tan spot had established for the first time in Latvia in 1994. Epidemic of this disease was observed in Latvia in 1998. Development of tan spot were investigated in field experiments at the Research and Training Farm “Peterlauki” of Latvia University of Agriculture in 1998–2001. Level of incidence and severity of tan spot differed depending on varieties and years. Severity of the di
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7

Garas, Antonios, Sophie Guthmuller, and Athanasios Lapatinas. "The development of nations conditions the disease space." PLOS ONE 16, no. 1 (2021): e0244843. http://dx.doi.org/10.1371/journal.pone.0244843.

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Using the economic complexity methodology on data for disease prevalence in 195 countries during the period of 1990-2016, we propose two new metrics for quantifying the disease space of countries. With these metrics, we analyze the geography of diseases and empirically investigate the effect of economic development on the health complexity of countries. We show that a higher income per capita increases the complexity of countries’ diseases. We also show that complex diseases tend to be non-ubiquitous diseases that are prevalent in disease-diversified (complex) countries, while non-complex dise
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8

L. Zoler, Mitchel. "Alzheimer's Disease Drug Development Targets Disease Modification." Caring for the Ages 16, no. 9 (2015): 4. http://dx.doi.org/10.1016/j.carage.2015.08.005.

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9

Hines, Pamela J. "From development to disease." Science 371, no. 6527 (2021): 358.10–360. http://dx.doi.org/10.1126/science.371.6527.358-j.

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10

Whitsett, Jeffrey A., and Timothy E. Weaver. "Alveolar Development and Disease." American Journal of Respiratory Cell and Molecular Biology 53, no. 1 (2015): 1–7. http://dx.doi.org/10.1165/rcmb.2015-0128ps.

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11

Bloom, David E., David Canning, and Günther Fink. "Disease and Development Revisited." Journal of Political Economy 122, no. 6 (2014): 1355–66. http://dx.doi.org/10.1086/677189.

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12

Bujosa, Francesc. "Economic development and disease." Lancet 354 (December 1999): SIV19. http://dx.doi.org/10.1016/s0140-6736(99)90362-8.

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13

Millen, Kathleen J., and Joseph G. Gleeson. "Cerebellar development and disease." Current Opinion in Neurobiology 18, no. 1 (2008): 12–19. http://dx.doi.org/10.1016/j.conb.2008.05.010.

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14

Miller, Geoffrey. "Neuromuscular development and disease." Neuromuscular Disorders 3, no. 1 (1993): 90. http://dx.doi.org/10.1016/0960-8966(93)90050-t.

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15

Cano, David A., Matthias Hebrok, and Martin Zenker. "Pancreatic Development and Disease." Gastroenterology 132, no. 2 (2007): 745–62. http://dx.doi.org/10.1053/j.gastro.2006.12.054.

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16

Panos, Leonidas D. "Alzheimer's Disease Drug Development." Current Alzheimer Research 21, no. 10 (2025): 691–92. https://doi.org/10.2174/156720502110250304104224.

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17

FURUKAWA, Fumiko, Noriyoshi TANAKA, Mitsunori MIYASHITA, Haruko SHIKIMORI, and Hiroaki KANAZAWA. "A Protective Mattress Development for Patients with Peripheral Vascular Disease." Japanese Journal of Ergonomics 48, no. 4 (2012): 196–203. http://dx.doi.org/10.5100/jje.48.196.

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18

Katu, Amina H. "The Role of Epigenetics in Disease Development." RESEARCH INVENTION JOURNAL OF PUBLIC HEALTH AND PHARMACY 3, no. 2 (2024): 41–44. http://dx.doi.org/10.59298/rijpp/2024/3234144.

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Анотація:
Epigenetics, the study of heritable changes in gene expression without alterations to the DNA sequence, plays a critical role in the development of various diseases. These epigenetic mechanisms, which include DNA methylation, histone modifications, and non-coding RNA-mediated gene silencing, regulate essential cellular processes such as differentiation, development, and tissue-specific gene expression. Environmental factors and lifestyle choices influence these epigenetic changes, often leading to disease by modifying transcriptional profiles. This paper discusses the role of epigenetics in th
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19

Kadirovna, Muratova Saodat, Shukurova Nodira Tillayevna, Baratov Bobur, and Teshayev Shoxjahon. "PREDICTIVE MODELING OF THE PROBABILITY OF DEVELOPING PERIODONTAL DISEASES IN PATIENTS WITH CARDIOVASCULAR DISEASE." European International Journal of Multidisciplinary Research and Management Studies 4, no. 4 (2024): 65–70. http://dx.doi.org/10.55640/eijmrms-04-04-10.

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Анотація:
Currently, the forecast of the development of pathology is an important part of all branches of healthcare. [3,4,5]. However, despite the importance and scientific and practical significance of forecasting in dentistry, at present we have not found information about predictive models of individual risk of developing periodontitis in patients with hypertension.
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20

Murrell, Adele, Paul J. Hurd, and Ian C. Wood. "Epigenetic Mechanisms in Development and Disease." Biochemical Society Transactions 41, no. 3 (2013): 697–99. http://dx.doi.org/10.1042/bst20130051.

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Анотація:
Our advances in technology allow us to sequence DNA to uncover genetic differences not only between individuals, but also between normal and diseased cells within an individual. However, there is still a lot we have yet to understand regarding the epigenetic mechanisms that also contribute to our individuality and to disease. The 80th Biochemical Society Annual Symposium entitled Epigenetic Mechanisms in Development and Disease brought together some leading researchers in the field who discussed their latest insights into epigenetic mechanisms. Methylation of DNA has been the focus of much stu
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21

Saad, Sonia, and Hui Chen. "Diet and Disease Development: Mechanisms, Prevention, and Treatment." Nutrients 16, no. 21 (2024): 3676. http://dx.doi.org/10.3390/nu16213676.

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Анотація:
The overall aims of this Special Issue “Diet and Disease Development: Mechanisms, Prevention and Treatment” are to describe and emphasise the importance of diet in disease development; understand the mechanism(s) whereby an unhealthy diet can induce various diseases; examine the potential effects of natural compounds or extracts on disease prevention or treatment; and determine whether nutrients and their metabolites can be used as biomarkers to diagnose certain diseases [...]
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22

Conesa, Xavier, Xavier González, Eduard Siles, Fèlix Parals, and Josep Novell. "Simultaneous Development of Dieterich Disease and Freiberg Disease." Journal of Foot and Ankle Surgery 52, no. 3 (2013): 389–92. http://dx.doi.org/10.1053/j.jfas.2012.12.014.

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23

Espay, Alberto J., Lorraine V. Kalia, Ziv Gan-Or, et al. "Disease modification and biomarker development in Parkinson disease." Neurology 94, no. 11 (2020): 481–94. http://dx.doi.org/10.1212/wnl.0000000000009107.

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A fundamental question in advancing Parkinson disease (PD) research is whether it represents one disorder or many. Does each genetic PD inform a common pathobiology or represent a unique entity? Do the similarities between genetic and idiopathic forms of PD outweigh the differences? If aggregates of α-synuclein in Lewy bodies and Lewy neurites are present in most (α-synucleinopathies), are they also etiopathogenically significant in each (α-synuclein pathogenesis)? Does it matter that postmortem studies in PD have demonstrated that mixed protein-aggregate pathology is the rule and pure α-synuc
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24

Venkatesh, Vaibhav, Deena C. Mendez, Rajshekhar T S, and Sharath Balakrishna. "Molecular factors in the development of vitiligo." JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES 09, no. 3 (2019): 61–68. http://dx.doi.org/10.58739/jcbs/v09i3.8.

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Vitiligo is a chronic autoimmune disease, caused due to selective destruction of melanocytes. It is characterized by depigmentation of skin. The mechanisms that underlie this phenomenon has not been clearly understood. Therefore, the aim of this review was to collate all the emerging information regarding the involvement of molecular components in vitiligo pathogenesis. Initial surveys suggested that certain chemicals were responsible for causing this skin disease. Recent genetic studies like twin studies show that vitiligo arises due to hereditary factors. Certain predisposing risk variants h
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25

Wenda, Alex, Nanda Putri Miefthawati, and Mas’ud Zein. "The Development of Diseases Identification System in Paddy Plant Using Image Processing Technique." Proceeding International Conference on Science and Engineering 2 (March 1, 2019): 231–36. http://dx.doi.org/10.14421/icse.v2.92.

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There are three types of paddy leaf disease that have similar symptoms, making it difficult for farmers to identify them, namely Blast Disease, Brown-Spot Disease, and Narrow Brown-Spot Disease. This paper aims to develop an application to identify paddy leaf disease automatically. Several important aspects of the development of software engineering such as usability, interactivity, and simplicity have been considered. Image processing techniques, namely Blobs analysis and color segmentation are used to get the characteristics of diseased leaf; these characteristics are then used to identify t
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26

Lundstrom, Kenneth. "Epigenetics, Nutrition, Disease and Drug Development." Current Drug Discovery Technologies 16, no. 4 (2019): 386–91. http://dx.doi.org/10.2174/1570163815666180419154954.

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Анотація:
Epigenetic mechanisms comprising of DNA methylation, histone modifications and gene silencing by RNA interference have been strongly linked to the development and progression of various diseases. These findings have triggered research on epigenetic functions and signal pathways as targets for novel drug discovery. Dietary intake has also presented significant influence on human health and disease development and nutritional modifications have proven important in prevention, but also the treatment of disease. Moreover, a strong link between nutrition and epigenetic changes has been established.
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27

Divvela, Satya Srirama Karthik, Darius Saberi, and Beate Brand-Saberi. "Atoh8 in Development and Disease." Biology 11, no. 1 (2022): 136. http://dx.doi.org/10.3390/biology11010136.

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Анотація:
Atoh8 belongs to a large superfamily of transcriptional regulators called basic helix-loop-helix (bHLH) proteins. bHLH proteins have been identified in a wide range of organisms from yeast to humans. The members of this special group of transcription factors were found to be involved not only in embryonic development but also in disease initiation and its progression. Given their importance in several fundamental processes, the translation, subcellular location and turnover of bHLH proteins is tightly regulated. Alterations in the expression of bHLH proteins have been associated with multiple
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28

Heward, Joanne, and Stephen C. L. Gough. "Genetic Susceptibility to the Development of Autoimmune Disease." Clinical Science 93, no. 6 (1997): 479–91. http://dx.doi.org/10.1042/cs0930479.

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Анотація:
1. Autoimmune diseases are common conditions which appear to develop in genetically susceptible individuals, with expression of disease being modified by permissive and protective environments. Familial clustering and data from twin studies provided the impetus for the search for putative loci. Both the candidate gene approach in population-based case-control studies and entire genome screening in families have helped identify susceptibility genes in a number of autoimmune diseases. 2. After the first genome screen in type 1 (insulin-dependent) diabetes mellitus it seems likely that most autoi
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29

Currer, Currer. "Fetal Exposure to Arsenic Results in the Development of Multiple Risk Factors for the Development of Metabolic Syndrome." Clinical and Medical Research and Studies 2, no. 4 (2023): 1–2. https://doi.org/10.59468/2836-8525/034.

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Анотація:
Exposure to arsenic is a major concern in the United States and worldwide, since this metalloid has been associated with a number of ailments, including cardiovascular and metabolic diseases. Environmental exposures to toxicants throughout fetal development have been shown to play a critical role as triggers of adult disease.
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30

Liersch, Ruediger, and Michael Detmar. "Lymphangiogenesis in development and disease." Thrombosis and Haemostasis 98, no. 08 (2007): 304–10. http://dx.doi.org/10.1160/th07-04-0238.

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SummaryThe lymphatic vascular system plays an important role in the maintenance of fluid homeostasis, in the afferent immune response, in the intestinal lipid uptake and in the metastatic spread of malignant cells. The recent discovery of specific markers and growth factors for lymphatic endothelium and the establishment of genetic mouse models with impairment of lymphatic function have provided novel insights into the molecular control of the lymphatic system in physiology and in embryonic development. They have also identified molecular pathways whose mutational inactivation leads to human d
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31

Han, Hyeseung, and Daeun Park. "Development and Validation of Disease Mindset Measurement Scale." Korean Association of Health and Medical Sociology 64 (December 31, 2023): 63–97. http://dx.doi.org/10.37243/kahms.2023.64.63.

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Анотація:
In recent years, the global COVID-19 pandemic has heightened public interest in diseases, prompting this study to focus on developing a novel disease mindset scale. It is expected that the diversity of diseases we encounter will continue to expand. The rapid spread of COVID-19 and the resultant societal standstill have exposed the profound impact of high mortality rates on individuals' mental health, leading to increased anxiety and depression. Traditionally, research on diseases has been confined to the realm of health. However, advancements in medical technology emphasize the importance of d
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32

Goncharov, V. E., V. M. Kozidubova, S. M. Doluda, E. N. Barycheva, and A. V. Gurnickiy. "Family impact on disease development." Shidnoevropejskij zurnal vnutrisnoi ta simejnoi medicini 2020, no. 2 (2020): 75–79. http://dx.doi.org/10.15407/internalmed2020.02.075.

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33

Chaitra, P., and NandaKishore Bala. "Onychomycosis: Insights in disease development." Muller Journal of Medical Sciences and Research 5, no. 2 (2014): 101. http://dx.doi.org/10.4103/0975-9727.135735.

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34

Apter, Jeffrey T. "New Drug Development --- Alzheimer' Disease." Neuropsychopharmacology 11, no. 4 (1994): 264. http://dx.doi.org/10.1038/sj.npp.1380130.

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35

VANČURA, A., and M. CHYTIL. "The Development of Hypertensive Disease." Acta Medica Scandinavica 154, S312 (2009): 109–13. http://dx.doi.org/10.1111/j.0954-6820.1956.tb16956.x.

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36

Barta, Andrea, and Michael F. Jantsch. "RNA in Disease and development." RNA Biology 14, no. 5 (2017): 457–59. http://dx.doi.org/10.1080/15476286.2017.1316929.

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37

Roses, Allen D., and Menelas N. Pangalos. "Drug Development and Alzheimer Disease." American Journal of Geriatric Psychiatry 11, no. 2 (2003): 123–30. http://dx.doi.org/10.1097/00019442-200303000-00003.

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38

Goshomi, Unice. "Fetal development and coronavirus disease." African Journal of Midwifery and Women's Health 14, no. 3 (2020): 1. http://dx.doi.org/10.12968/ajmw.2020.0041.

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39

Alderton, Gemma. "Improving Alzheimer's disease drug development." Science 362, no. 6420 (2018): 1259.14–1261. http://dx.doi.org/10.1126/science.362.6420.1259-n.

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40

Ferreira, A. "Development of renal bone disease." European Journal of Clinical Investigation 36, s2 (2006): 2–12. http://dx.doi.org/10.1111/j.1365-2362.2006.01661.x.

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41

Ghosh, Anirban, Wolfgang J. Streit, Luisa Minghetti, and Anirban Basu. "Microglia in Development and Disease." Clinical and Developmental Immunology 2013 (2013): 1–2. http://dx.doi.org/10.1155/2013/736459.

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42

Gomase, Virendra S., and Akshay N. Parundekar. "microRNA: human disease and development." International Journal of Bioinformatics Research and Applications 5, no. 5 (2009): 479. http://dx.doi.org/10.1504/ijbra.2009.028678.

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43

Lehmann, Ordan J., Jane C. Sowden, Peter Carlsson, Tim Jordan, and Shomi S. Bhattacharya. "Fox's in development and disease." Trends in Genetics 19, no. 6 (2003): 339–44. http://dx.doi.org/10.1016/s0168-9525(03)00111-2.

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44

Ko, Myunggon, Dong H. Sohn, Heekyoung Chung, and Rho H. Seong. "Chromatin remodeling, development and disease." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 647, no. 1-2 (2008): 59–67. http://dx.doi.org/10.1016/j.mrfmmm.2008.08.004.

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45

Hüppi, Petra, Stephane Sizonenko, and Maurizio Amato. "Lung Disease and Brain Development." Neonatology 89, no. 4 (2006): 284–97. http://dx.doi.org/10.1159/000092865.

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46

Sonnenberg, Arnoud, and Ronald K. H. Liem. "Plakins in development and disease." Experimental Cell Research 313, no. 10 (2007): 2189–203. http://dx.doi.org/10.1016/j.yexcr.2007.03.039.

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47

Roque, M., and A. Craveiro. "Psychiatric Development in Huntington Disease." European Psychiatry 24, S1 (2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)71201-5.

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Анотація:
Huntington Disease (HD) is an untreatable condition with an hereditary basis, autosomal dominant, progressive and Neurodegenerative, with average beginning age in-between 35 and 44 years old. Choreic movements are the major feature of this disease, but the most precocious symptoms are psychiatric alterations. Studies reveal depression numbers to be double than those found in the general population, with disturbing numbers in suicide attempts. Behavioural alterations (psychotic symptoms, agitation, irritability, and insomnia) may become severe in long-term course.Objective:The authors’ aim is t
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48

Durbeej, Madeleine, Michael D. Henry, and Kevin P. Campbell. "Dystroglycan in development and disease." Current Opinion in Cell Biology 10, no. 5 (1998): 594–601. http://dx.doi.org/10.1016/s0955-0674(98)80034-3.

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49

Vogel, Tanja, and Silke Lassmann. "Epigenetics: development, dynamics and disease." Cell and Tissue Research 356, no. 3 (2014): 451–55. http://dx.doi.org/10.1007/s00441-014-1916-7.

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50

Milligan, Paul, and Michael Pugh Thomas. "Relationships between development and disease." Environmentalist 6, no. 2 (1986): 129–40. http://dx.doi.org/10.1007/bf02277236.

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