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1

Chin, Jason A., and Bauer E. Sumpio. "Diabetes Mellitus and Peripheral Vascular Disease." Clinics in Podiatric Medicine and Surgery 31, no. 1 (2014): 11–26. http://dx.doi.org/10.1016/j.cpm.2013.09.001.

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2

Khuda, Bux Mangrio *. Dr. Rafi Ahmed Ghori Dr. Naveed Aslam Lashari Dr. Hamid Nawaz Ali Memon Dr. Umair Ahmed Ghori Dr. Sumera Bukhari and Dr. Zulfiqar Ali Qutrio Baloch. "PERIPHERAL VASCULAR DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS." Indo American Journal of Pharmaceutical Sciences 04, no. 09 (2017): 3278–82. https://doi.org/10.5281/zenodo.996557.

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Анотація:
Objective: To determine the frequency of peripheral vascular disease in patients with type 2 diabetes mellitus. Patients and Methods: The present study was undertaken at tertiary care hospital Hyderabad. Total fifty patients with type 2 diabetes mellitus were studied which were admitted to medical wards and all these cases fulfilled our inclusion. while the data was collected on pre-designed proforma and analyzed in SPSS 16. The inclusion criteria of the study were diagnosed patients of type 2 diabetes mellitus of ≥35 years of age, either gender and ≥ 3 years duration of diabetes mellitus. The
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3

Schaper, N. C., M. H. Nabuurs-Franssen, and M. S. P. Huijberts. "Peripheral vascular disease and Type 2 diabetes mellitus." Diabetes/Metabolism Research and Reviews 16, S1 (2000): S11—S15. http://dx.doi.org/10.1002/1520-7560(200009/10)16:1+<::aid-dmrr112>3.0.co;2-v.

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4

Martha Lilac Ketisha Antoine, Malyn, Yancheng Xu, and Dodji Kossi Djakpo. "Atherosclerotic disease and diabetes mellitus." International Journal of Medicine 8, no. 1 (2020): 4. http://dx.doi.org/10.14419/ijm.v8i1.30213.

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Анотація:
The macro-vascular complications (cardiovascular, neurovascular and peripheral vascular diseases) observed in diabetic patients usually develop secondary to the presence of atherosclerotic diseases. In diabetic patients chronically elevated blood glucose levels play a major role in contributing to the development of the disease; however, in addition to hyperglycaemia, other factors such as hypertension, dyslipidaemia and obesity also contribute to the development of this condition. Despite the fact that further research is required to fully establish the relationship between hyperglycaemia and
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5

Tyagi, Vinod, Abhishek Gupta, Naman Bansal, and S. K. Virmani. "Prevalence of peripheral artery disease in diabetes mellitus: research article." International Journal of Research in Medical Sciences 5, no. 11 (2017): 4881. http://dx.doi.org/10.18203/2320-6012.ijrms20174938.

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Background: Peripheral artery disease is a major macrovascular complication of diabetes mellitus. Patients with diabetes mellitus have an increased prevalence of PAD. The ankle brachial pressure index is an easy, non invasive and often under utilised tool for diagnosis of PAD.Methods: In the present study, 100 patients from Western Uttar Pradesh with diabetes mellitus were enrolled to find out prevalence of peripheral vascular disease using ankle brachial pressure index and study the associated risk factors.Results: 59 percent of the subjects were female and 41 percent were male. Ankle-brachia
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6

Marwaha, T. S., G. Jain, A. Khurana, P. S. Dhoat, and B. Kumar. "Peripheral Vascular Disease a Silent Assassin:Rising Trend in State of Punjab." International Journal of Medical and Dental Sciences 2, no. 2 (2013): 189. http://dx.doi.org/10.19056/ijmdsjssmes/2013/v2i2/86781.

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Анотація:
Peripheral vascular disease is a major macrovascular complication of diabetes mellitus. This study was done to determine the prevalence of peripheral arterial disease in type 2 diabetes mellitus using the ankle brachial pressure index. An 12 MHz doppler probe was used in the arms and legs to assess the ankle brachial index (ABI) in 200 type 2 diabetes mellitus patients aged more than 40 years. Thorough history of patients including age, smoking history, history of symptoms of peripheral arterial disease, complete physical examination and routine investigations were collected at the time of enr
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7

Malla, Dipak, and Sukesh Purush Dhakal. "Clinical Analysis of Peripheral Vascular Diseade in Patients with Diabetes Mellitus." Journal of Diabetes and Endocrinology Association of Nepal 3, no. 2 (2019): 18–24. http://dx.doi.org/10.3126/jdean.v3i2.27520.

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Анотація:
Introduction: Diabetes Mellitus (DM) is clinical syndrome characterized by hyperglycemia due to absolute or relative deficiency of insulin. The metabolic dysregulation associated with DM causes multitude of secondary pathophysiological changes in multiple organ system causing macro vascular (coronary artery disease, peripheral vascular disease, cerebrovascular disease) and micro vascular (retinopathy, neuropathy, and nephropathy) complications. This study aimed to study the prevalence of peripheral vascular disease in patients with diabetic mellitus presenting to this tertiary care centre.&#x0
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8

YAVUZ, Senol, Ahmet Kağan AS, Mesut ENGİN, Nizamettin KOCA, and Soner CANDER. "Cardiovascular diseases and diabetes mellitus." European Research Journal 8, no. 4 (2022): 541–49. http://dx.doi.org/10.18621/eurj.1091928.

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Анотація:
Cardiovascular diseases are among the leading causes of death worldwide. Atherosclerotic cardiovascular diseases consist of a broad spectrum of diseases such as coronary artery disease, carotid artery disease, peripheral artery diseases, cerebral vascular diseases and visceral artery diseases. Although atherosclerosis occurs over time due to age; hypertension, hyperlipidemia, smoking, and diabetes mellitus are important factors that play a role in the emergence of atherosclerosis. Diabetes mellitus has an active role in the development of atherosclerotic cardiovascular disease. It is expected
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9

Dr., Tariq Zaffar Shaikh Dr. Abdul Ghani Rahimoon Dr. Faheem Ahmed Memon Dr. Hamid Nawaz Ali Memon Dr. Ali Raza Shaikh Dr. Alveena Batool Syed Dr. Samar Raza. "PERIPHERAL VASCULAR DISEASE IN DIABETIC FOOT ULCER." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 12 (2018): 17316–19. https://doi.org/10.5281/zenodo.2529207.

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<strong><em>Objective:</em></strong><em> To determine the frequency of peripheral vascular disease in diabetic foot ulcer.</em> <strong><em>Patients and Methods:</em></strong><em> The cross sectional study of six months was conducted on type 2 diabetic population with foot ulcer &gt; 35 year age and either gender presented at tertiary care hospital. The inclusion criteria were type 2 diabetic patients with diabetic foot infections will explore to have arterial Doppler study. The diabetic foot infection was considered as cellulitis of the foot, infected ulcers, abscess, gangrene/ necrosis of on
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10

Jiang, Wengao, Qiang Tang, Lei Zhang, Yinxue Chao, and Bing Hong. "Association of serum C1q tumour necrosis factor–related protein 9 with the severity of lower extremity peripheral arterial disease in type 2 diabetes patients." Diabetes and Vascular Disease Research 15, no. 3 (2018): 270–73. http://dx.doi.org/10.1177/1479164118763254.

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Анотація:
Objective: Recent studies have indicated the implication of C1q tumour necrosis factor–related protein 9 in vascular pathology of atherosclerosis. This study first investigated the association of C1q tumour necrosis factor–related protein 9 and the severity of lower extremity peripheral arterial disease in type 2 diabetes mellitus patients. Methods: A total of 200 patients with type 2 diabetes mellitus had ankle–brachial index examined in this cross-sectional study, 60 patients with ankle–brachial index of ⩽0.9 were diagnosed with peripheral arterial disease and further classified into mild, m
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11

Giannopoulos, Stefanos, and Ehrin J. Armstrong. "Diabetes mellitus: an important risk factor for peripheral vascular disease." Expert Review of Cardiovascular Therapy 18, no. 3 (2020): 131–37. http://dx.doi.org/10.1080/14779072.2020.1736562.

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12

Munazza Shaikh, Sadiq Ali Khowaja, Allah Bachayo Rajar, Ghulam Hussain Baloch, Partab Puri, and Tariq Feroz Memon. "Macrovascular Complications and their risk factors in Type 2 Diabetic Patients in Hyderabad, Pakistan." JMMC 11, no. 2 (2021): 52–57. http://dx.doi.org/10.62118/jmmc.v11i2.157.

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Анотація:
Introduction: Diabetes mellitus (DM), is the universally occurring non-communicable disease as well as exemplary health problem affecting peo-ple worldwide.1 The number of cases of DM are rising at an enormous pace irrespective of any age, gender, economic status or ethnicity around the globe.Objective: To evaluate the macro-vascular complications and its correlation with different risk factors among type-2 diabetic patients.Methodology: This cross-sectional study was conducted at Red Crescent General Hospital Latifabad Hyderabad from October 2018 to October 2020. Type 2 diabetics of either ge
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13

Saienko, Yanina, Yevgen Marushko, Ozerianska, et al. "Chronic kidney disease in a patient with type 1 diabetes mellitus: expectations and reality based on a case report." Diabetes Obesity Metabolic Syndrome, no. 5 (October 27, 2023): 38–44. http://dx.doi.org/10.57105/2415-7252-2023-5-02.

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Decompensation of diabetes mellitus leads to serious consequences due to the presence of vascular complications: microangiopathy (retinopathy and nephropathy), macroangiopathy (myocardial infarction, stroke, peripheral arterial disease), neuropathy (diabetic peripheral and autonomic neuropathy). The professional approach of a specialist and a patient to the treatment of diabetes leads to a favorable course of the disease and the achievement of compensation. The presented clinical case clearly shows the connection between the decompensation of diabetes mellitus and the development of severe con
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14

Andersen, Charles A. "Noninvasive Assessment of Lower-extremity Hemodynamics in Individuals with Diabetes Mellitus." Journal of the American Podiatric Medical Association 100, no. 5 (2010): 406–11. http://dx.doi.org/10.7547/1000406.

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The timely and accurate noninvasive assessment of peripheral arterial disease is a critical component of a limb preservation initiative in patients with diabetes mellitus. Noninvasive vascular studies can be useful in screening patients with diabetes for peripheral arterial disease. In patients with clinical signs or symptoms, noninvasive vascular studies provide crucial information on the presence, location, and severity of peripheral arterial disease and an objective assessment of the potential for primary healing of an index wound or a surgical incision. Appropriately selected noninvasive v
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15

Armen, Joseph, and Bryan W. Smith. "Exercise considerations in coronary artery disease, peripheral vascular disease, and diabetes mellitus." Clinics in Sports Medicine 22, no. 1 (2003): 123–33. http://dx.doi.org/10.1016/s0278-5919(02)00035-2.

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16

Cimminiello, C., and M. Milani. "Diabetes mellitus and peripheral vascular disease: is aspirin effective in preventing vascular events?" Diabetologia 39, no. 11 (1996): 1402–4. http://dx.doi.org/10.1007/s001250050590.

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17

Felício, João Soares, Camila Cavalcante Koury, Nathalie Abdallah Zahalan, et al. "Ankle-brachial index and peripheral arterial disease: An evaluation including a type 2 diabetes mellitus drug-naïve patients cohort." Diabetes and Vascular Disease Research 16, no. 4 (2019): 344–50. http://dx.doi.org/10.1177/1479164119829385.

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Анотація:
Background: Peripheral arterial disease in patients with type 2 diabetes mellitus is an important risk factor for vascular events. Recommendations about whether ankle-brachial index should be performed differ depending on the source; therefore, it is necessary to re-evaluate the most important risk factors associated with peripheral arterial disease and whether it is useful to perform ankle-brachial index in newly diagnosed and drug-naïve patients with diabetes, independent of age or peripheral arterial disease symptoms. Methods: A total of 711 subjects were divided into groups: group 1, 600 t
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18

Prof., Dr. Bikha Ram Devrajani Prof. Dr. Shamsuddin Shaikh *. Dr. Naveed Aslam Lashari Dr. Syed Zulfiquar Ali Shah Dr. Sajjad Ali. "ANKLE BRACHIAL INDEX (ABI) IN PATIENTS WITH TYPE 2 DIABETES MELLITUS." Indo American Journal of Pharmaceutical Sciences 04, no. 11 (2017): 4353–57. https://doi.org/10.5281/zenodo.1064337.

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Objective: To estimate the ankle brachial index in patients with type 2 diabetes mellitus at tertiary care hospital Patients and Methods: All the diabetic population (&ge; 3 years duration) between 40 - 80 years of age, either gender without previous diagnosis of peripheral arterial disease or clinical suggestive of intermittent claudication intermittent visited at tertiary care hospital from January 2016 to June 2016 &amp; gave voluntary consent to participate in the study were recruited. The highest systolic blood pressure of lower limbs was divided by highest systolic blood pressure of lowe
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19

Fadini, Gian Paolo, Gaia Spinetti, Marianna Santopaolo, and Paolo Madeddu. "Impaired Regeneration Contributes to Poor Outcomes in Diabetic Peripheral Artery Disease." Arteriosclerosis, Thrombosis, and Vascular Biology 40, no. 1 (2020): 34–44. http://dx.doi.org/10.1161/atvbaha.119.312863.

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Diabetes mellitus increases the risk and accelerates the course of peripheral artery disease, making patients more susceptible to ischemic events and infections and delaying tissue healing. Current understanding of pathogenic mechanisms is mainly based on the negative influence of diabetes mellitus on atherosclerotic disease and inflammation. In recent years, the novel concept that diabetes mellitus can impinge on endogenous regenerative processes has been introduced. Diabetes mellitus affects regeneration at the local level, disturbing proper angiogenesis, collateral artery formation, and mus
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20

BARRADAS, M. A., D. S. GILL, V. A. FONSECA, D. P. MIKHAILIDIS, and P. DANDONA. "Intraplatelet serotonin in patients with diabetes mellitus and peripheral vascular disease." European Journal of Clinical Investigation 18, no. 4 (1988): 399–404. http://dx.doi.org/10.1111/j.1365-2362.1988.tb01030.x.

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21

Rekleiti, M., I. Kyriazis, M. Saridi, P. Kyloudis, G. Wozniak, and Z. Roupa. "Depression at patients with diabetes mellitus type II and macro vascular diseases." European Psychiatry 26, S2 (2011): 679. http://dx.doi.org/10.1016/s0924-9338(11)72385-9.

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IntroductionThe presence of macro vascular diseases is common among patients with diabetes mellitus, with result the increase of danger for depression appearance.The attack of greater vessels (macro vascular disease) conducts to the appearance of coronary disease, vascular brain episodes(strokes) and peripheral vasculopathy.Aimof this study was the examination of the relation between depression and the existence of macro vascular diseases at patients with diabetes mellitus type II.Material-methods164 diabetics were examined (72 male and 92 female, medieval age 66,9 ± 11,53 years), at diabetolo
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22

Gracheva, Svetlana Alexandrovna, Inna Igorevna Klefortova, and Minara Shamkhalovna Shamkhalova. "Prevalence of combined atherosclerotic vascular lesions in patients with diabetes mellitus." Diabetes mellitus 15, no. 1 (2012): 49–55. http://dx.doi.org/10.14341/2072-0351-5979.

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During latest decade, as threat of acute complications of diabetes mellitus was surmounted, cardiovascular complications became leadingcause of death. Clinical manifestation of coronary, brachiocephalic and renal atherosclerosis is quite dramatic in diabetes mellitus,which determines extent of dissemination and intensity of lesions. Combination of these mutually confounding conditions is a characteristicproblem of patients with diabetes mellitus. Presence of 2+ risk factors (one of which is diabetes mellitus in itself) requiresactive examination in order to rule out coronary, brachiocephalic,
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23

Jackson, M. H., A. Collier, J. J. Nicoll, et al. "Neutrophil Count and Activation in Vascular Disease." Scottish Medical Journal 37, no. 2 (1992): 41–43. http://dx.doi.org/10.1177/003693309203700205.

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An elevated peripheral leucocyte count is associated with an increased risk of myocardial infarction and progression of coronary artery disease. The aim of this study was to determine neutrophil count and activation, measured as an increase in plasma neutrophil elastase, in patients with stable ischaemic heart disease, insulin-dependent diabetes mellitus and essential hypertension compared with a comparable group of control subjects. Neutrophil count and neutrophil elastase were raised significantly for patients with ischaemic heart disease (p&lt; 0.005; p&lt; 0.002), diabetes mellitus (p&lt;
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24

Manoli, Arthur. "A Long Posterior Flap in Below-Knee Amputations for Peripheral Vascular Disease: Rationale and Technique." Foot & Ankle International 19, no. 2 (1998): 110–12. http://dx.doi.org/10.1177/107110079801900210.

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25

Newman, Jonathan D., Caron B. Rockman, Mikhail Kosiborod, et al. "Diabetes mellitus is a coronary heart disease risk equivalent for peripheral vascular disease." American Heart Journal 184 (February 2017): 114–20. http://dx.doi.org/10.1016/j.ahj.2016.09.002.

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26

Lampeter, E., B. Schwippert, and D. Tschöpe. "Megakaryocytes and Platelets in Diabetes Mellitus." Hämostaseologie 16, no. 02 (1996): 144–50. http://dx.doi.org/10.1055/s-0038-1656649.

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SummaryIn patients with diabetes mellitus vascular diseases and related complications still represent the main cause of death. Neuropathy, nephropathy, retinopathy and disturbed nutritive tissue perfusion result from reduced capillary microcirculation. Macroangiopathic mechanisms lead to accelerated cerebral, coronary and peripheral artery disease precipitating life terminating thrombotic events superimposed to those vascular lesions. Thus morbidity and mortality depend mainly on vascular complications. The functional thromboresistance is reduced in the diabetic state with hyperactive platelet
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27

Afa, Bayramova. "Diabetes mellitus and heart diseases." Global Journal of Obesity, Diabetes and Metabolic Syndrome 5, no. 1 (2018): 003–7. https://doi.org/10.17352/2455-8583.000031.

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Diabetes mellitus is recognized by World Health Organisation experts as a non-communicable epidemic and represents a serious medical and social problem. In 2012, suffered of diabetes mellitus about 6.4% (285 million) of the world&rsquo;s inhabitants. By 2030, the number of patients is expected to increase to 7.7% (439 million people) [1]. Coronary heart disease is the leading cause of death in patients with diabetes [2], with 90% of these patients suffering from type 2 diabetes (diabetes mellitus 2) [3]. The presence of diabetes is associated with the emergence of all forms of coronary heart d
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28

Dr. Tariq Farhad, Dr. Muhammad Rahim Burghri, Dr. Muhammad Uzair Memon, Dr. Soha Fatima, Dr. Yasir Latif, and Haji Abdullah Memon. "Vascular Complications and their Risk Factors in Patients of Diabetes Mellitus, Type 2." Journal of Islamabad Medical & Dental College 11, no. 4 (2023): 196–203. http://dx.doi.org/10.35787/jimdc.v11i4.875.

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Introduction: To evaluate the vascular complications and their correlation with different risk factors among type-2 diabetic patients in Hyderabad, Sindh, Pakistan.&#x0D; Methodology: Cross-sectional study was conducted at the department of medicine Isra University Hospital, Hyderabad from March to September 2021. Type 2 diabetics of either sex, between ages 20 and 70 years, on diabetic medication, were included in the study. While patients with type I diabetes, unconscious or with any mental health issues were excluded. A Non-random consecutive sampling technique was applied for the selection
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29

Biryukova, E. V. "THE ROLE OF GLYCATED HEMOGLOBIN IN THE DIAGNOSIS AND IMPROVED PROGNOSIS OF DIABETES MELLITUS." Medical Council, no. 3 (December 30, 2017): 48–53. http://dx.doi.org/10.21518/2079-701x-2017-3-48-53.

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Анотація:
The focus on the problem of diabetes mellitus (DM) is associated with the increasing prevalence of the disease and the risk for the development of many vascular complications (nephropathy, retinopathy, lesions of the great vessels of the heart, brain, peripheral vascular disease of the lower limbs), in the development of which chronic hyperglycemia plays a crucial role. In 2011, the WHO decided that glycated hemoglobin (HbA1c) could be used as the diagnostic criterion for diabetes. The role of HbA1c in the choice of hypoglycemic therapy is invaluable. According to the Algorithms of Specialized
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30

Kondratiev, Y. Yu, V. V. Nosikov, and I. I. Dedov. "Polymorphic genetic markers and vascular complications of diabetes." Problems of Endocrinology 44, no. 1 (1998): 43–51. http://dx.doi.org/10.14341/probl199844143-51.

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Diabetes mellitus is a clinically and genetically heterogeneous disease characterized by absolute or relative insulin deficiency and (or) peripheral tissue resistance to the hormone. Each of these disorders individually or in various combinations reduces tissue glucose consumption and increases the concentration of this monosaccharide in the patient’s blood. The state of hyperglycemia is a necessary and, over time, sufficient condition for the development of the so-called late complications of diabetes mellitus (mainly vascular - diabetic angiopathies). These chronic complications of diabetes
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31

Alam, Md Rezaul, Ferdous Jahan, Muhammad Nazrul Islam, et al. "Prevalence of Macrovascular Complications among Diabetic Patients at a Tertiary Care Hospital in Bangladesh." Scholars Journal of Applied Medical Sciences 13, no. 06 (2025): 1301–7. https://doi.org/10.36347/sjams.2025.v13i06.010.

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Background: Macrovascular complications such as coronary artery disease, stroke, and peripheral arterial disease are major causes of illness and death in patients with diabetes mellitus (DM). These complications are often overlooked in nephrology settings, where patients commonly have overlapping conditions like chronic kidney disease (CKD). Aim: To determine the prevalence of macrovascular complications among patients with type 2 diabetes mellitus. Method: This hospital-based cross-sectional study was conducted at Bangladesh Medical University (BMU), Dhaka, involving 283 adult patients with t
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32

Skryabina, A. A. "Infectious Diseases in Patients with Diabetes Mellitus: Literature Review." Medicina 12, no. 1 (2024): 37–52. http://dx.doi.org/10.29234/2308-9113-2024-12-1-37-52.

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Diabetes mellitus is associated with increased susceptibility to infectious diseases. This is due to the fact that uncontrolled hyperglycemia is accompanied by impaired innate and adaptive immune response, micro- and macroangiopathies, neuropathy, and decreased urine antibacterial activity. Furthermore, complications of diabetes mellitus such as neuropathy and peripheral vascular disease can lead to skin ulceration with secondary bacterial infections. Bacteria can invade any organ of the human body, with the most common foci of infection in diabetes mellitus being the urinary tract, respirator
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33

Korada, H. Ya, E. Arora, Sh K. Rao, M. Hande, S. Shetty, and A. G. Maiya. "Plantar pressure distribution profile of type 2 diabetes mellitus with diabetic foot syndrome: A hospital-based observational study." Diabetes mellitus 24, no. 6 (2021): 548–52. http://dx.doi.org/10.14341/dm12723.

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INTRODUCTION: The prevalence of diabetic foot syndrome is increasing in the Indian population. It is a triad of neurological, vascular, and biomechanical changes due to long term diabetes mellitus (DM). Altered plantar pressure distribution is a risk factor for developing diabetic foot ulcers. The purpose of this study is to evaluate the altered plantar pressure distribution in diabetic peripheral neuropathy individuals with peripheral vascular disease in comparison with diabetic peripheral neuropathy and non-diabetic neuropathy. Therefore, the objective of the study is to evaluate the plantar
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34

Dafriani, Putri. "Efek Kedelai Terhadap Faal Ginjal Diabetes Melitus." Ners Jurnal Keperawatan 7, no. 2 (2011): 176–82. https://doi.org/10.25077/njk.v7i2.26.

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Diabetes mellitus is a metabolism disease associated with a number of microvascular (retinopathy, neuropathy and nephropathy) and macrovascular (ischemic heart disease, cerebrovascular disease and peripheral vascular diseases) complications. Soybeans have been consumed for a long time as an important protein source to complement grain protein soybean contain various nutritious and functional components such as isoflavonoids, which are beneficial against stress oxidative. This study aimed to explain soybean effect to nephropathy diabetic. Soybean have some advantages like isoflavonoids, protein
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35

Mohan, V., G. Premalatha, and N. G. Sastry. "Peripheral vascular disease in non-insulin-dependent diabetes mellitus in South India." Diabetes Research and Clinical Practice 27, no. 3 (1995): 235–40. http://dx.doi.org/10.1016/0168-8227(95)01048-i.

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36

Abouhamda, Ayman, Majid Alturkstani, and Yousef Jan. "Lower sensitivity of ankle-brachial index measurements among people suffering with diabetes-associated vascular disorders: A systematic review." SAGE Open Medicine 7 (January 2019): 205031211983503. http://dx.doi.org/10.1177/2050312119835038.

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Diabetes mellitus is a systemic disease affecting microvascular and macrovascular systems and is considered as the strongest risk factor for peripheral arterial disease. Although the prevalence of the peripheral arterial disease is high among people living with diabetes, its severity is not accurately detected with the prevalent diagnostic methodologies. The ankle-brachial index measurement is a simple, objective, and reliable tool for diagnosis of peripheral arterial disease. However, it is of limited value in the diagnosis of peripheral arterial disease among diabetic patients due to its low
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Sunil, Junapudi, Yasodha Janapati, and Syam Junapudi. "The classical Biomarkers to Predict Diabetes Mellitus." Asian Journal of Medical Research & Health Sciences (A-JMRHS) 2, no. 1 (2024): 5. http://dx.doi.org/10.5455/ajmrhs.1107202300018.

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Diabetes mellitus is metabolic disorders; depicted by elevated blood glucose levels ascribed to a futile, scanty or sojourns production of insulin. Enduring complications of the disease have been related to peripheral vascular problems, steering to cardiovascular diseases, stroke, diabetic retinopathy, nephropathy and foot. Precise monitoring of these complications and early therapy stages will allow improvement in prevention and treatment approaches. The availability of measurable, accurate and reproducible biomarkers allow the patient to receive timely enactment of personalized therapies and
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38

Ito, Wulf D., Natalie Lund, Hendrik Sager, Wiebke Becker, and Ulrich Wenzel. "Differential impact of diabetes mellitus type II and arterial hypertension on collateral artery growth and concomitant macrophage accumulation." Vasa 44, no. 1 (2015): 31–41. http://dx.doi.org/10.1024/0301-1526/a000404.

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Background: Diabetes mellitus type II and arterial hypertension are major risk factors for peripheral arterial disease and have been considered to reduce collateral growth (arteriogenesis). Collateral growth proceeds through different stages. Vascular proliferation and macrophage accumulation are hallmarks of early collateral growth. Material and methods: We here compare the impact of arterial hypertension and diabetes mellitus type II on collateral proliferation (Brdu incorporation) and macrophage accumulation (ED 2 staining) as well as collateral vessel function (collateral conductance) in a
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39

Karandikar, Sangram, and Tushar S. Khachane. "CLINICORADIOLOGICAL ASSESSMENT OF PERIPHERAL ARTERIOPATHY IN DIABETICS." International Journal of Advanced Research 9, no. 08 (2021): 633–36. http://dx.doi.org/10.21474/ijar01/13307.

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Background :The steady rise in prevalence of Diabetes mellitus has resulted in increase in the complications related to diabetes. Peripheral arterial disease in diabetes is an independent risk factor for subsequent ulceration and limb loss in diabetics. It is therefore essential that peripheral arterial disease is identified in all patients with diabetics. Methods : The present prospective observational study conducted at a tertiary centre in central India was aimed at clinico-radiological assessment of lower limb vessels in patients with diabetes. 184 patients with diabetes were assessed clin
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40

Viigimaa, Margus, Alexandros Sachinidis, Maria Toumpourleka, Konstantinos Koutsampasopoulos, Signe Alliksoo, and Tiina Titma. "Macrovascular Complications of Type 2 Diabetes Mellitus." Current Vascular Pharmacology 18, no. 2 (2020): 110–16. http://dx.doi.org/10.2174/1570161117666190405165151.

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Background: Type 2 diabetes mellitus (T2DM) has emerged as a pandemic. It has different complications, both microvascular and macrovascular. Objective: The purpose of this review is to summarize the different types of macrovascular complications associated with T2DM. Methods: A comprehensive review of the literature was performed to identify clinical studies, which determine the macrovascular complications associated with T2DM. Results: Macrovascular complications of T2DM include coronary heart disease, cardiomyopathy, arrhythmias and sudden death, cerebrovascular disease and peripheral artery
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41

Diyan Pratama Sari and Diana Dayaningsih. "PENERAPAN SPA KAKI DIABETIK TERHADAP SIRKULASI DARAH PERIFER PADA PASIEN DIABETES MELLITUS TIPE 2DI WILAYAH BINAAN PUSKESMAS ROWOSARI SEMARANG." JURNAL KEPERAWATAN SISTHANA 6, no. 1 (2021): 8–14. http://dx.doi.org/10.55606/sisthana.v6i1.71.

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Diabetes mellitus type 2 is most often occurring and cause acute vascular diseases of vascular perifer and the loss of perifer blood circulation. One management of peripheral blood circulation in people with diabetes mellitus is to use diabetic feet spa therapy. The purpose of this case study is to describe the application of diabetic feet spa to peripheral blood circulation after and before therapy of diabetic feet spa. The type of the study belongs descriptive with a case study approach. The subjects of this study were two patients with type 2 diabetes mellitus, experienced mild peripheral b
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42

Giraldo-Grueso, Manuel, and Darío Echeverri. "From Endothelial Dysfunction to Arterial Stiffness in Diabetes Mellitus." Current Diabetes Reviews 16, no. 3 (2020): 230–37. http://dx.doi.org/10.2174/1573399814666181017120415.

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Prevalence of diabetes mellitus has increased drastically over time, especially in more populous countries such as the United States, India, and China. Patients with diabetes have an increased risk of major cardiovascular events such as acute myocardial infarction, cerebrovascular disease, and peripheral vascular disease. Arterial stiffness is a process related to aging and vascular, metabolic, cellular and physiological deterioration. In recent years, it has been described as an independent predictor of cardiovascular mortality and coronary artery disease. Additionally, it plays an important
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43

Helfand, Arthur E. "Foot Problems in Older Patients." Journal of the American Podiatric Medical Association 94, no. 3 (2004): 293–304. http://dx.doi.org/10.7547/0940293.

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This study sought to demonstrate the prevalence of foot conditions in older individuals and their association with chronic risk diseases such as diabetes mellitus, peripheral arterial disease, and arthritis, and to develop care plans to reduce complications from local foot problems and chronic diseases. One thousand individuals older than 65 years who were ambulatory and not institutionalized underwent a standardized and validated podogeriatric examination assessment protocol or index. Overall, 74.6% of all patients had a history of pain, 57.2% were receiving current care for diabetes mellitus
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44

Gupta, Abhishek, Vinod Kumar Tyagi, Naman Bansal, S. K. Virmani, and T. R. Sirohi. "Comparison of ankle brachial pressure index to arterial doppler USG in the diagnosis of peripheral vascular disease in diabetes mellitus." International Journal of Advances in Medicine 4, no. 6 (2017): 1562. http://dx.doi.org/10.18203/2349-3933.ijam20175135.

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Background: Peripheral artery disease(PAD) is a major macrovascular complication of diabetes mellitus. Patients with diabetes mellitus have an increased prevalence of PAD. However, due to associated neuropathy, common symptoms such as claudication are often masked and such patients often diagnosed late when limb threatening ischemia has already set in. Arterial colour doppler ultrasonography and ankle brachial pressure index are easy, non- invasive and often underutilised tools for diagnosis of PAD.Methods: In the present study, 100 diabetic patients were enrolled to study the comparison of An
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45

Naqvi, Dr Abbas, Dr A. K. Shadani, and Dr Shubhangi Gupta. "Serum Homocysteine Level in Patients of Type 2 Diabetes Mellitus with Macrovascular Complications." International Journal of Science and Healthcare Research 7, no. 2 (2022): 53–63. http://dx.doi.org/10.52403/ijshr.20220409.

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The risk of CVD in men with DM is 3-fold and in women with DM 5-fold in comparison to those without diabetes(1). Diabetes is a recognized independent risk factor for stroke and is associated with higher morbidity and mortality(2-4). The severity and duration of DM are important predictors of both the incidence and the extent of PAD, as observed in United Kingdom Prospective Diabetes Study, where each 1% increase in glycosylated hemoglobin was correlated with a 28% increase in incidence of PAD, and higher rates of death, microvascular complications and major amputation.(5,6) Homocysteine concen
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46

Devkota, Pramod, and Shiraz Ahmad. "Major Lower Extremity Amputations due to Diabetes Mellitus Complications." Hong Kong Journal of Orthopaedic Research 4, no. 2 (2021): 29–31. http://dx.doi.org/10.37515/ortho.8231.4202.

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Background: Lower limbs ulcers and wounds, Charcot foot with the presence of peripheral neuropathy or peripheral vascular disease are common complications of the diabetes mellitus (DM). Major extremity amputations (below and above knee) are one of the common surgical procedures performed due to DM complications. Objective: To review the amputations performed due to diabetes mellitus (DM) complications with other associated illness, commonly isolated bacteria, and the demography of the patients in a public general hospital. Materials and Methods: We retrospectively reviewed the cases of above a
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47

Aditya Wahyu Febrianto and Dwi Yogo Budi Prabowo. "EFFECT OF FOOT EXERCISES ON INDEX BRACHIAL ANKLE VALUES IN PATIENTS WITH DIABETES MELLITUS." Nursing Care Journal 2, no. 2 (2025): 57–62. https://doi.org/10.63520/ncj.v2i2.649.

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Diabetes Mellitus is a hereditary disease and a non-communicable disease which is always experiencing an increase in the number of patients. Diabetes Mellitus can cause complications of microangiopathy and macroangiopathy. One of the complications experienced by diabetes mellitus patients is neuropathy and peripheral arterial disease. One way to find out about circulation disorders is to carry out an Ankle Brachial Index (ABI) examination. One exercise to overcome vascular problems is diabetic foot exercises. Foot exercises are carried out with the aim of preventing complications of tissue dam
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48

Govindarajan Venguidesvarane, Akila, Aliya Jasmine, Samya Varadarajan, et al. "Prevalence of Vascular Complications Among Type 2 Diabetic Patients in a Rural Health Center in South India." Journal of Primary Care & Community Health 11 (January 2020): 215013272095996. http://dx.doi.org/10.1177/2150132720959962.

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Introduction: Vascular complications are the major cause of morbidity in patients with diabetes mellitus. Screening for these complications is crucial in early detection and tertiary prevention. Hence, this study aimed at finding the prevalence of micro and macrovascular complications and their associated factors in type 2 diabetes mellitus patients in a rural health center by using simple and easily available tools. Methodology: This hospital based cross sectional study was conducted in Rural Health and Training Centre (RHTC) of Sri Ramachandra medical college from Jan 2017 to Aug 2017. All t
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Kawata, Ryuichi, Kazuhiko Nakakimura, Mishiya Matsumoto, Kouji Kawai, Mitsuru Kunihiro, and Takefumi Sakabe. "Cerebrovascular CO2Reactivity during Anesthesia in Patients with Diabetes Mellitus and Peripheral Vascular Disease." Anesthesiology 89, no. 4 (1998): 887–93. http://dx.doi.org/10.1097/00000542-199810000-00013.

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Background Diabetes mellitus (DM) and systemic atherosclerosis are risk factors for stroke. Although the origins of increased risk are complex, one possibility is that cerebrovascular reactivity is impaired and does not allow the brain to compensate for aberrations in physiology. The current study tested this issue by evaluating mean blood flow velocity of the middle cerebral artery (Vmca) and carbon dioxide reactivity during anesthesia in patients with DM and peripheral vascular disease (PVD). Methods Fifty-two patients were observed: 20 patients with DM (the DM group), 12 patients with PVD (
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UCHIMURA, I., T. BABA, M. MOROHOSHI, et al. "F286. Interleukin-6 mediates hemorheological abnormality in diabetes mellitus with peripheral vascular disease." Biorheology 32, no. 2-3 (1995): 385. http://dx.doi.org/10.1016/0006-355x(95)92398-t.

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