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Дисертації з теми "Diabetic Chronic Kidney Disease"

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1

Wong, May Yue Wai. "Novel anti-fibrotic agents in acute and chronic kidney disease." Thesis, The University of Sydney, 2020. https://hdl.handle.net/2123/22015.

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The thesis spans the spectrum of causative and therapeutic aspects of chronic kidney disease (CKD), which is a significant and growing health burden. While it is desirable that these findings will translate into effective strategies to prevent CKD, kidney impairment is frequently diagnosed when advanced renal fibrosis has already developed. Thus, the second part of this thesis focuses on therapy and explores whether anti-inflammatory or anti fibrotic agents such as semicarbazide sensitive amine oxidase (SSAO) inhibitor or cationic-independent mannose 6-phosphate receptor (CI-6MPR) inhibitors s
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2

Palanca, Ana. "Subclinical atherosclerosis in chronic kidney disease and diabetes." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/670707.

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La malaltia cardiovascular és la primera causa de morbiditat i mortalitat mundial. Els individus amb diabetis i malaltia renal crònica (MRC) presenten un major risc d’esdeveniments cardiovasculars (ECV) respecte a la població general. En la diabetis, l’increment de el risc cardiovascular és heterogeni i s’ha relacionat amb el grau d’afectació renal. D’altra banda, els algoritmes tradicionals per calcular el risc cardiovascular no traslladen amb suficient precisió el risc futur de ECV. L’avaluació de l’aterosclerosi subclínica (AS) mitjançant ecografia multiterritorial representa una eina vàlid
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3

Shaman, Ahmed M. "Improving outcomes for patients with chronic kidney disease." Thesis, The University of Sydney, 2020. https://hdl.handle.net/2123/22328.

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There is clear evidence in the literature that the global burden of chronic kidney disease (CKD) is increasing. CKD patients are at high risk of cardiovascular morbidity and mortality which appeared to proportionally increase as kidney function deteriorates toward end-stage kidney disease (ESKD) requiring dialysis. Given the increasing prevalence, worsened outcomes associated with CKD as well as the financial cost associated with its management, there is a clear need for evidence-based interventions to lower the risk and improve outcomes in this high-risk population. This thesis aimed at
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4

Sukkar, Louisa. "Improving outcomes in chronic kidney disease and its associated comorbidities." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/25667.

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Background: Chronic kidney disease (CKD) and its associated comorbidities such as diabetes and cardiovascular disease (CVD) are major drivers of death and disability around the world. Methods: This thesis by publication aims to examine the burden of CKD and diabetes in the community and explores the ways in which this burden can be ameliorated. These aims are achieved by various methodologies. A novel comprehensive population-based data linkage study is used to estimate CKD and diabetes incidence and associations as well as assesses health service delivery of proven cardioprotective treatments
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5

Walter, Debra L. "Renal Consequences of Coxsackievirus Infection and Type 1 Diabetes in Non-obese Diabetic Mice." Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1526020616767063.

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6

Herrera-Añazco, Percy, Alvaro Taype-Rondan, María Lazo-Porras, Quintanilla E. Alberto, Victor Manuel Ortiz-Soriano, and Adrian V. Hernandez. "Prevalence of chronic kidney disease in Peruvian primary care setting." BMJ Publishing Group Ltd, 2017. http://hdl.handle.net/10757/622208.

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Background: Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in primary care setting. Methods: We did a retrospective secondary analysis of a database from the Diabetes and Hypertension Primary Care Center of the Peruvian Social Security System (EsSalud) in Lima, Peru. We defined CKD as the presence of eGFR <60 mL/min and/or albuminuria >30 mg/day in 24 h, according to Kidney Disease: Improving Global Outcomes
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7

Glastras, Sarah Jean. "Maternal obesity predisposes offspring towards the development of chronic kidney disease." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/15709.

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Obesity together with insulin resistance promotes multiple metabolic abnormalities and is strongly associated with increased risk of chronic disease including type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease (CKD). The incidence of obesity is rising and affects all different stages of the lifespan. Importantly, obesity in women of reproductive has potential ramifications for offspring health. Maternal obesity is known to influence offspring development of obesity, T2D and CVD. In contrast, the relationship between maternal obesity and CKD has been less clearly def
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8

Mcdonald, H. I. "The epidemiology of infections among older people with diabetes mellitus and chronic kidney disease." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2015. http://researchonline.lshtm.ac.uk/2528130/.

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This thesis describes the epidemiology of community-acquired infections among older people with diabetes without a history of renal replacement therapy, according to markers of chronic kidney disease (CKD): proteinuria and reduced estimated glomerular filtration rate (eGFR). The thesis uses linked electronic health records from primary and secondary care, and mortality records. Among a cohort of 219,145 patients with diabetes aged ≥65 years there was a high burden of community-acquired infection: lower respiratory tract infections (LRTIs) having the highest crude rate (152.7/1,000 years) follo
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9

Vergara, Arana Ander. "Mecanismos de acción del bloqueo SGLT2 en la protección cardiorrenal en la diabetes tipo 2." Doctoral thesis, Universitat Autònoma de Barcelona, 2021. http://hdl.handle.net/10803/674051.

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La malaltia renal diabètica (MRD) és la principal causa d’inici de diàlisi en el món i s’acompanya d’una elevada morbimortalitat. Fins al 2016 només dos grups farmacològics que bloquegen el sistema renina-angiotensina (SRA): els inhibidors de l’enzim convertidor d’angiotensina (IECAs) i els antagonistes el receptor d’angiotensina II (ARA2), van demostrar frenar la progressió de la MRD. Recentment, dos grups farmacològics: els inhibidors del cotransportador de sodi-glucosa tipus 2 (iSGLT2) i els antagonistes selectius del receptor d’endotelina (ARE) han demostrat efectes protectors enfront de l
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10

Pereira, Filipa Alexandra Antunes Vences de Matos. "Patient associations: raising awareness on chronic diseases." Master's thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/16582.

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Mestrado em Biomedicina Farmacêutica<br>The patient associations assume a significant role in representing the patients’ rights, sharing information on the diseases, accessing the available resources, maintaining important interactions with other relevant stakeholders and facing challenges. These organizations provide an important support not only to the patients, but also to their families and friends, who are most of the times their direct caregivers. Currently, the patient empowerment has been highly discussed. This project aims to demonstrate in five different clinical disorders what ar
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11

Thomas, Nicola. "The development and evaluation of a self-management package for people with diabetes at risk of chronic kidney disease." Thesis, City, University of London, 2010. http://openaccess.city.ac.uk/16816/.

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Анотація:
Progression of chronic kidney disease (CKD) in diabetes can be slowed by strict blood pressure and blood sugar control, prescription of medicines that modify the renin-angiotensin system and lifestyle changes, such as smoking cessation. Because of the large numbers of people with diabetes whose condition progresses (and eventually require dialysis or transplantation), it is possible that the management of their diabetes remains sub-optimal. The overall purpose of this thesis is to develop, test and evaluate an educational package to help people self-manage their risk of CKD progression. This t
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12

Lei, Yutian [Verfasser], та Hans-Joachim [Akademischer Betreuer] Anders. "Interleukin-1β inhibition for chronic kidney disease in obese mice with type 2 diabetes / Yutian Lei ; Betreuer: Hans-Joachim Anders". München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2021. http://d-nb.info/1239049307/34.

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13

Hassouneh, Ramzi. "Prostaglandin E2 Receptor 3 (EP3) Contributes to Polyuria, Glomerular Hyperfiltration, and Renal Injury in Diabetes." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32773.

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Анотація:
Cyclooxygenases (COXs) and their main renal product, prostaglandin E2 (PGE2), regulate many physiological renal functions and are involved in the pathogenesis of diabetic kidney disease. The PGE2 receptor EP3 has been repeatedly shown to be upregulated during diabetes. Physiologically, EP3 is best recognized to act as a diuretic by antagonizing arginine-vasopressin (AVP)-mediated water reabsorption. Incidentally, the first renal manifestation of diabetes is polyuria, which may trigger a cascade of events leading to DN. We hypothesize that EP3 contributes to polyuria and kidney dysfunction duri
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14

Murugan, Ashley. "A retrospective review with prospective follow up of renal function, blood pressure and proteinuria post living donor nephrectomy at Groote Schuur Hospital, Cape Town South Africa." Master's thesis, Faculty of Health Sciences, 2020. http://hdl.handle.net/11427/32310.

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Introduction: Renal transplantation is the treatment of choice for patients with end stage renal disease [ESRD]. An increased risk of ESRD has been demonstrated when comparing donors to age matched healthy non-donors. There are no outcome data in Africa on long term donor renal function or mortality. Therefore, this study aimed to assess long term health complications in the living donor population and evaluate risk factors associated with poor health outcomes of the donors. Methods: This was a retrospective review with prospective follow up of persons undergoing living related donor nephrecto
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15

Jakobsson, Stina. "Cardiovascular disease and diabetes or renal insufficiency : the risk of ischemic stroke and risk factor intervention." Doctoral thesis, Umeå universitet, Kardiologi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-109785.

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Background In patients with diabetes mellitus (DM) or chronic kidney disease (CKD), established cardiovascular disease (CVD) is associated with an increased risk of recurrent events and poor outcome. Ischemic stroke after an acute myocardial infarction (AMI) is a devastating event that carries high risks of decreased patient independence and death. Among patients with DM or CKD, the risk of an ischemic stroke within a year following an AMI is not known. Improved risk factor control is required to reduce the likelihood of CVD recurrence. Guidelines recommend target lipid profile and blood press
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16

Silva, Andréa Cruvinel Rocha. "Função e integridade renal de cães com diabetes mellitus." Universidade Federal de Goiás, 2012. http://repositorio.bc.ufg.br/tede/handle/tede/3145.

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Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2014-09-23T18:10:18Z No. of bitstreams: 2 Dissertacao final_MESTRADO_ANDRÉA_pdf.pdf: 1572790 bytes, checksum: 50d50dc5744b87dfbdd59a0cd86e00d3 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Jaqueline Silva (jtas29@gmail.com) on 2014-09-23T18:34:46Z (GMT) No. of bitstreams: 2 Dissertacao final_MESTRADO_ANDRÉA_pdf.pdf: 1572790 bytes, checksum: 50d50dc5744b87dfbdd59a0cd86e00d3 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Made avai
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17

Soita, David Jonah. "Cardiovascular disease risk profile of the South-African mixed ancestry population with high incidence of diabetes mellitus: baseline and three year follow-up." Thesis, Cape Peninsula University of Technology, 2013. http://hdl.handle.net/20.500.11838/1519.

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THESIS SUBMITED IN FULFILMENT OF THE REQUIREMENT FOR THE AWARD OF THE DEGREE OF DOCTOR OF TECHNOLOGY OF BIOMEDICAL TECHNOLOGTY IN THE FACULTY OF HEALTH AND WELLNESS SCIENCES AT THE CAPE PENINSULA UNIVERSITY OF TECHNOLOGY SUPERVISORS: PROF T.E. MATSHA PROF R.T. ERASMUS DR A. ZEMLIN SUBMITED DECEMBER 2013<br>Introduction: Cardiovascular diseases (CVD) have become the leading cause of morbidity and mortality amongst the global population. Originally thought to be a health burden of high income countries, the prevalence is rapidly increasing in developing countries. For example, in 2008, an
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18

Ninichuk, Volha. "The role of chemokine receptor CCR1-dependent macrophage recruitment for the progression of chronic kidney disease in murine Alport syndrome or type 2 diabetes." Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-79657.

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19

Daniel, Juliana Maria Rodrigues. "Associação do grau de albuminúria com nível de atividade física e capacidade funcional em portadores de diabetes mellitus." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/153468.

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Submitted by JULIANA MARIA RODRIGUES DANIEL null (juhrodriguess2@hotmail.com) on 2018-04-10T14:12:54Z No. of bitstreams: 1 Dissertação_jufinal.pdf: 777093 bytes, checksum: ec4f007a485719ddaa9a669b5cc08706 (MD5)<br>Approved for entry into archive by Luciana Pizzani null (luciana@btu.unesp.br) on 2018-04-10T19:36:57Z (GMT) No. of bitstreams: 1 daniel_jmr_me_bot.pdf: 777093 bytes, checksum: ec4f007a485719ddaa9a669b5cc08706 (MD5)<br>Made available in DSpace on 2018-04-10T19:36:57Z (GMT). No. of bitstreams: 1 daniel_jmr_me_bot.pdf: 777093 bytes, checksum: ec4f007a485719ddaa9a669b5cc08706 (MD5)
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20

Björklund, Fredrik. "Platelet reactivity and comorbidities in acute coronary syndrome." Doctoral thesis, Umeå universitet, Institutionen för folkhälsa och klinisk medicin, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-51096.

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Background In the event of an acute coronary syndrome (ACS), the risk of death and complications such as stroke and re-infarction is high during the first month. Diabetes, impaired kidney function, elevated markers of systemic inflammation and high level of platelet reactivity have all been associated with worsened prognosis in ACS patients. Impaired kidney function is a condition with high cardiovascular morbidity and there is an established association between level of kidney function and outcome in the event of an ACS. Aims We sought to investigate the level of platelet reactivity during th
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21

Aguiar, Ana Paula Costa de. "Aplicabilidade da estimativa da hemoglobina glicada a partir da albumina glicada em pacientes com diabetes mellitus tipo 2 e diferentes graus de comprometimento renal." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/157622.

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O diabetes mellitus (DM) é uma doença crônica com alto índice de morbidade e mortalidade, sendo considerado um dos maiores problemas de saúde pública do século 21, afetando aproximadamente 415 milhões de pessoas. As complicações em longo prazo do DM incluem a doença renal, a qual pode levar à falência renal, a retinopatia com perda potencial da visão e neuropatia, bem como o risco de amputações. A hemoglobina glicada (A1c) é considerada o parâmetro de referência na avaliação do controle glicêmico de pacientes com DM. No entanto, a mensuração da A1c pode não ser adequada para avaliar as variaçõ
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22

Banerjee, Srikanta. "Inflammatory Markers Associated With Disease Progression of Cardiorenal Syndrome." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/1433.

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An increase in cellular inflammatory biomarkers directly increases the risk of cardiovascular disease (CVD). Using the social ecological and biomedical theories, the study examined quantitatively how specific inflammatory biomarkers are associated with cardiorenal syndrome (CRS), a potential complication of hypertension and diabetes, and how sociodemographic factors modify this association in the U.S. adult population. A retrospective secondary data analysis of the data collected from National Health and Nutrition Examination Survey (NHANES) 1999-2010 was utilized to evaluate these hypotheses.
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23

Bezerra, Aline Junqueira. "Análise retrospectiva de fatores envolvidos na progressão da doença renal em pacientes atendidos no Ambulatório de Uremia do HCFMRP-USP." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/17/17138/tde-03122013-095721/.

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Introdução: O perfil de morbidade e mortalidade no Brasil passou por uma transição demográfica, com o aumento da prevalência de doenças crônicas na população em geral, tais como diabetes mellitus (DM) e hipertensão arterial (HA), e como consequência, a doença renal crônica (DRC). Na última década, a DRC tem sido apresentada como um grande desafio para a saúde pública no Brasil e no mundo. Objetivo: O objetivo deste estudo foi identificar os fatores envolvidos na progressão da doença renal dos pacientes atendidos no Ambulatório de Uremia do HCFMRP-USP. Material e métodos: Trata-se de um estudo
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24

Lafuente, Maria João Fernandes. "Sinais precoces : um projeto piloto de saúde preventiva - deteção de hipertiroidismo, diabetes mellitus e doença renal crónica em gatos geriátricos." Master's thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2014. http://hdl.handle.net/10400.5/6795.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Esta dissertação de Mestrado Integrado de Medicina Veterinária reflete o projeto Sinais Precoces, que se insere na área da saúde preventiva, e que foi desenvolvido e implementado no Hospital Veterinário das Laranjeiras. Nas últimas décadas o número e a importância social dos animais de companhia aumentaram substancialmente. Como consequência da relação de proximidade entre estes e os seus donos, e do aumento da esperança média de vida, cresce na medicina veterinária a necessidade de colocar o foco na prevenção das doenças geriátricas
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25

Motrapu, Manga [Verfasser], and Hans-Joachim [Akademischer Betreuer] Anders. "Targeting the residual progression of chronic kidney disease with type-2 diabetes beyond the renoprotective effects of a metformin-ramipril-empagliflozin combination / Manga Motrapu ; Betreuer: Hans-Joachim Anders." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2021. http://d-nb.info/1239049609/34.

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26

Galil, Arise Garcia de Siqueira. "Influência do uso do tabaco em população com múltiplas condições crônicas." Universidade Federal de Juiz de Fora (UFJF), 2016. https://repositorio.ufjf.br/jspui/handle/ufjf/3695.

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Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-03-14T14:20:34Z No. of bitstreams: 1 arisegarciadesiqueiragalil.pdf: 3825957 bytes, checksum: 8e6346876438a33406d4180499457d56 (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-03-17T14:50:06Z (GMT) No. of bitstreams: 1 arisegarciadesiqueiragalil.pdf: 3825957 bytes, checksum: 8e6346876438a33406d4180499457d56 (MD5)<br>Made available in DSpace on 2017-03-17T14:50:06Z (GMT). No. of bitstreams: 1 arisegarciadesiqueiragalil.pdf: 3825957 bytes, checksum: 8e6346876438a33406d4180499457d56 (M
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27

Contreras, Macazana Roxana Milagros. "Estimación de la tasa de filtración glomerular usando las ecuaciones CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) y MDRD 4 (Modification of Diet in Renal Disease) en pacientes diabéticos tipo 2 atendidos en HNERM." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2014. https://hdl.handle.net/20.500.12672/8961.

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Publicación a texto completo no autorizada por el autor<br>Determina la correlación y el grado de concordancia entre la ecuación de CKD-EPI y MDRD con la depuración de creatinina en orina de 24 horas para la estimación de la tasa de filtrado glomerular en pacientes diabéticos tipo 2, mayores de edad que acuden al servicio de Patología Clínica sección Bioquímica depuración de creatinina del HNERM, en el periodo octubre a diciembre 2013. Es un estudio Analítico comparativo, prospectivo observacional. Se obtuvo una muestra de 152 pacientes diabéticos, se aplicó el test de correlación de spearma
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28

Philips, L. G. "Disease management in chronic kidney disease /." abstract and full text PDF (free order & download UNR users only), 2005. http://0-wwwlib.umi.com.innopac.library.unr.edu/dissertations/fullcit/1430446.

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Thesis (M.B.A.)--University of Nevada, Reno, 2005.<br>"May, 2005." Includes bibliographical references (leaves 92-97). Online version available on the World Wide Web. Library also has microfilm. Ann Arbor, Mich. : ProQuest Information and Learning Company, [2005]. 1 microfilm reel ; 35 mm.
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29

Wei, Jin. "Acute Kidney Injury and Chronic Kidney Disease." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6780.

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Ischemia and reperfusion are natural steps during kidney transplantation, and IRI is considered one of the most important nonspecific factors affecting allograft dysfunction. Transplanted organs experience several episodes of ischemia, in which cold ischemia occurs during allograft storage in preservation solutions. Even though cold ischemia has been studied extensively, all of the studies have been carried out in vitro and ex vivo models. There is no in vivo model available to examine renal IRI induced solely by cold ischemia. In the present study, we developed an in vivo mouse model to study
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30

Bermejo, García Sheila. "Enfermedad renal en el paciente diabético. Utilidad de la biopsia renal." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2020. http://hdl.handle.net/10803/670395.

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La diabetis mellitus és una malaltia d’una crucial importància a nivell mundial per la seva elevada prevalença i augment de la incidència. Una de les seves complicacions més rellevants és el desenvolupament de malaltia renal crònica. La malaltia renal diabètica és la primera causa d’inici de teràpia renal substitutiva en el nostre medi. L’ús de bloquejadors del sistema renina-angiotensina-aldosterona (BSRAA) ha demostrat un efecte beneficiós en els pacients diabètics amb afectació renal lleu, tot i així, aquest benefici a la malaltia renal crònica avançada no és tant clar. Per altra banda, la
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31

Wong, Germaine. "Cancer and chronic kidney disease." Thesis, The University of Sydney, 2008. https://hdl.handle.net/2123/28229.

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Introduction Chronic kidney disease (CKD) is a common and important public health problem, with significant impact on the person’s quality of life and chances of survival. Cardiovascular disease is major cause of morbidity and mortality among people with CKD. Cancer is also a well-recognised complication in people on dialysis and with kidney transplants, but has not been adequately assessed in people with mild to moderately reduced kidney function. It is uncertain whether the basis of such increased risk in the end-stage kidney and transplant populations is solely related to their immunocompr
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32

Gumbrevicius, Iara. "Efeito da farinha de banana verde sobre o funcionamento intestinal de pacientes diabéticos, constipados, com doença renal crônica, submetidos a tratamento de hemodiálise." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/89/89131/tde-07122016-170137/.

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A farinha de banana verde (FBV), fonte de amido resistente, pode melhorar o funcionamento intestinal de indivíduos saudáveis, porém, esta propriedade ainda não foi estudada em voluntários com enfermidades que causam constipação intestinal. O objetivo deste estudo foi avaliar o efeito do consumo regular e não diário da farinha de banana verde sobre o funcionamento intestinal de pacientes diabéticos, com constipação intestinal, doença renal crônica, tratados com hemodiálise. Em ensaio clínico prospectivo, modelo cross-over, 21 pacientes do Centro de Nefrologia de Amparo-SP foram divididos em doi
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33

Figuiredo-Dias, Vilani [UNIFESP]. "Fatores associados à hipovitaminose D na doença renal crônica." Universidade Federal de São Paulo (UNIFESP), 2011. http://repositorio.unifesp.br/handle/11600/19159.

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Made available in DSpace on 2015-12-06T23:03:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2011<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Fundação Oswaldo Ramos<br>Background: Hypovitaminosis D is highly prevalent among chronic kidney disease patients and it has been associated with worse outcome even in the earlier stages of the disease. Objective: This study aimed to investigate the risk factors for hypovitaminosis D in nondialyzed chronic kidney disease patients. Design: This cross-se
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34

Tomlinson, Laurie. "Arterial Stiffness and Chronic Kidney Disease." Thesis, University of Brighton, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518323.

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Introduction: Chronic kidney disease (CKD) common, particularly in the elderly, and is linked to an increased risk of cardiovascular disease (CVD). This is partly explained by joint risk factors such as hypertension and diabetes but novel risk factors such as arterial stiffness, arterial calcification and endothelial dysfunction may play a role. Our aims were 1) to prospectively investigate whether aortic stiffness was linked with rate of decline of renal dysfunction, 2) to investigate the associations of arterial stiffness in patients with moderate renal dysfunction, and 3) to investigate whe
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35

Navaneethan, Sankar. "METABOLIC SYNDROME AND CHRONIC KIDNEY DISEASE." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1401967446.

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36

Xie, Jeffrey Xinshuo. "Molecular Insights into Chronic Kidney Disease." University of Toledo Health Science Campus / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=mco1500201100900825.

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37

White, Joanna D. "Investigations into feline chronic kidney disease." Thesis, The University of Sydney, 2010. https://hdl.handle.net/2123/28931.

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Chronic kidney disease (CKD) is arguably the most common disease of older cats. A disproportionate number of younger, male cats with CKD was identified among a cohort of cats with CKD and was hypothesised to be due to membranous glomerulopathy or an FIV associated nephropathy. Examination of epidemiologic, histologic, immunohistologic and survival data revealed an association between the presence of CKD and FIV infection among young cats and an adverse effect of FIV infection on survival among cats with CKD, but no specific histological changes were seen among FIV positive cats. Glomer
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38

So, Beng Hock. "Chronic kidney disease : determining chronicity, prevalence, variation and survival in a community chronic kidney disease (CKD) cohort." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/30671/.

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Chronic kidney disease (CKD) is insidious and most cases are diagnosed through opportunistic serum creatinine (SCr) testing before symptoms develop. However, efforts to accurately assess prevalence have been hampered by the lack of a universally agreed definition of SCr thresholds for the diagnosis of CKD. At the turn of the millennium, two crucial developments occurred. The first was the description of the Modification of Diet in Renal Disease estimated Glomerular Filtration Rate (eGFR) which closely correlated to cumbersome measured GFR and could be used instead in daily clinical practice. T
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39

Darisipudi, Venkata Surya Narayana Murty. "Chemokines and cysteine proteases in diabetic kidney disease." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-173379.

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40

Betonico, Carolina de Castro Rocha. "Efeito da insulina glargina sobre o controle glicêmico e risco de hipoglicemia em pacientes portadores de diabetes mellitus tipo 2 e doença renal crônica estágios 3 e 4: ensaio clínico, controlado e randomizado." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-05042017-153224/.

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Diabetes mellitus (DM) é uma das principais causas de doença renal crônica terminal. Na doença renal diabética (DRD) observa-se um curso bifásico no padrão glicêmico, na fase inicial o aumento da resistência insulínica induz a hiperglicemia e, com perda progressiva da taxa de filtração glomerular, há redução na depuração dos medicamentos anti-hiperglicemiantes e insulina, aumentando o risco de hipoglicemias. Portanto, diante da perda da função renal, a reavaliação da terapia hipoglicemiante e ajustes constantes nas doses de insulina são necessários, com intuito de otimizar o controle glicêmico
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41

Johnston, Nicklett Johnston. "The Effect of Health Literacy in Low Estimated Glomerular Filtration and Diabetes." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3895.

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Health literacy is widespread, but its potential is not recognized. By not recognizing health literacy, patients have the burden of coping with diabetes with renal complications without full knowledge of their responsibility to their health. The focus of the project was to assess participants with diabetes with low health literacy and low mean glomerular filtration rate (eGFR). The project goal was achieved by the assessment of the participants' health literacy and eGFR before and after education for their diabetes, then assessed to determine if teaching the participants would improve their he
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42

Müller, Tilman [Verfasser]. "Apelinergic system in the kidney: implications for diabetic kidney disease / Tilman Müller." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2020. http://d-nb.info/1218075961/34.

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43

Clark, Laura Elizabeth. "The epidemiology of chronic kidney disease in Grampian." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=33407.

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44

Hermans, Marcus Matheus Hendrik. "Arterial wall abnormalities in chronic kidney disease." Maastricht : Maastricht : Universitaire Pers Maastricht ; University Library, Universiteit Maastricht [host], 2007. http://arno.unimaas.nl/show.cgi?fid=9384.

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45

Parham, Rhian. "Caregiver burden in paediatric chronic kidney disease." Thesis, Canterbury Christ Church University, 2011. http://create.canterbury.ac.uk/10347/.

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Section A provides an overview of the role of family caregivers of individuals with chronic illness, and describes key conceptualisations and theories posited in the caregiver literature. This is followed by an overview of research conducted with caregivers of children with chronic kidney disease (CKD), a summary of the limitations of this research, and suggestions for future research. Section B Despite a recognised need to monitor caregiver burden in caregivers of children with CKD, there is no measurement tool currently available to meet this aim. The present research documents the developme
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46

Hill, C. "Diabetic kidney disease : a study of management and outcomes." Thesis, Queen's University Belfast, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676518.

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Diabetes mellitus is the most common cause of end-stage renal disease requiring renal replacement therapy in the United Kingdom. However, many aspects of the prevalence, management and outcomes of diabetic patients with chronic kidney disease (CKD) remain unclear. This thesis consists of three studies using local (Northern Irish) data, national data (from the National Diabetes Audit) and international data (combined as part of a multi-centre collaborative meta-analysis). Its aims were to assess the survival of Northern Irish diabetic patients with CKD, examine the prevalence and associations o
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47

Diamond-Stanic, Maggie Keck. "Diabetic Kidney Disease in the VCD Model of Menopause." Diss., The University of Arizona, 2008. http://hdl.handle.net/10150/195657.

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Kidney disease is a major complication of diabetes and accounts for one-third of all diabetes-related deaths. Estrogen is considered protective against cardiovascular and non-diabetic renal disease, however it is unclear if this protection extends to diabetes and diabetic kidney disease.To address these questions, we have used a new model of menopause in which repeated daily injections of 4-vinylcyclohexene (VCD) induces gradual ovarian failure in mice. Unlike with ovariectomy, the VCD model preserves the gradual transition into ovarian failure (OF) (modeling perimenopause). Also, following
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48

Melin, Jan. "Renal Ischemia/Reperfusion Injury in Diabetes : Experimental Studies in the Rat." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5264-7/.

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49

Owen, Paul. "Body composition and function in chronic kidney disease." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/14576/.

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Chronic kidney disease (CKD) is a significant public health issue. The uraemic milieu is associated with profound alterations in body composition and function. Therapeutic interventions to preserve renal function and to provide adequate homeostasis to improve outcomes in all stages of chronic kidney disease may promote other unwanted functional adversities which with careful attention to individualised treatment may be modifiable. The aim of this thesis is to clearly document these disorders of body composition and function and investigate whether commonly practiced interventions can indeed ha
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50

Chakrabarti, Shubro. "Mechanisms of fibrosis in feline chronic kidney disease." Thesis, Royal Veterinary College (University of London), 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572451.

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