Добірка наукової літератури з теми "DNA Synthesis"

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Статті в журналах з теми "DNA Synthesis"

1

Shaista Sabir and Naghmmana Rashid, Shaista Sabir and Naghmmana Rashid. "Organocatalyzed Synthesis, DNA Binding and Microbial Studies of Warfarin Analogues." Journal of the chemical society of pakistan 46, no. 1 (2024): 107. http://dx.doi.org/10.52568/001426/jcsp/46.01.2024.

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A noval chiral sec-amine/amidine-base hybrid catalyst, N [S-carbonylprolyl] cyclohexyl Amine is described, which is able to catalyze conjugate addition of 6-Methyl-4-hydroxypyran and 2-Hydroxy-naphthaquinone with various benzylideneacetones through Michael reactions that directly gives anticoagulant Warfarin analogues. These analogues were prepared in good yields (54–82%) and in good enantiomeric excess (50–75%). Identification of synthesized compounds was done by physio-chemical properties and spectral analysis (1H-NMR andamp; 13C-NMR).These compounds were further investigated for their antim
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2

Shilkin, E. S., E. O. Boldinova, A. D. Stolyarenko, et al. "Translesion DNA Synthesis and Reinitiation of DNA Synthesis in Chemotherapy Resistance." Biochemistry (Moscow) 85, no. 8 (2020): 869–82. http://dx.doi.org/10.1134/s0006297920080039.

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3

Burke, Cassandra R., and Andrej Lupták. "DNA synthesis from diphosphate substrates by DNA polymerases." Proceedings of the National Academy of Sciences 115, no. 5 (2018): 980–85. http://dx.doi.org/10.1073/pnas.1712193115.

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The activity of DNA polymerase underlies numerous biotechnologies, cell division, and therapeutics, yet the enzyme remains incompletely understood. We demonstrate that both thermostable and mesophilic DNA polymerases readily utilize deoxyribonucleoside diphosphates (dNDPs) for DNA synthesis and inorganic phosphate for the reverse reaction, that is, phosphorolysis of DNA. For Taq DNA polymerase, the KMs of the dNDP and phosphate substrates are ∼20 and 200 times higher than for dNTP and pyrophosphate, respectively. DNA synthesis from dNDPs is about 17 times slower than from dNTPs, and DNA phosph
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4

Caruthers, Marvin H. "Chemical synthesis of DNA and DNA analogs." Accounts of Chemical Research 24, no. 9 (1991): 278–84. http://dx.doi.org/10.1021/ar00009a005.

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5

Church, Geoffrey A., Anindya Dasgupta, and Duncan W. Wilson. "Herpes Simplex Virus DNA Packaging without Measurable DNA Synthesis." Journal of Virology 72, no. 4 (1998): 2745–51. http://dx.doi.org/10.1128/jvi.72.4.2745-2751.1998.

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ABSTRACT Herpes simplex virus (HSV) type 1 DNA synthesis and packaging occur within the nuclei of infected cells; however, the extent to which the two processes are coupled remains unclear. Correct packaging is thought to be dependent upon DNA debranching or other repair processes, and such events commonly involve new DNA synthesis. Furthermore, the HSV UL15 gene product, essential for packaging, nevertheless localizes to sites of active DNA replication and may link the two events. It has previously been difficult to determine whether packaging requires concomitant DNA synthesis due to the com
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6

Sariban, E., R. S. Wu, L. C. Erickson, and W. M. Bonner. "Interrelationships of protein and DNA syntheses during replication of mammalian cells." Molecular and Cellular Biology 5, no. 6 (1985): 1279–86. http://dx.doi.org/10.1128/mcb.5.6.1279-1286.1985.

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During the replication of chromatin, the syntheses of the histone protein and DNA components are closely coordinated but not totally linked. The interrelationships of total protein synthesis, histone protein synthesis, DNA synthesis, and mRNA levels have been investigated in Chinese hamster ovary cells subjected to several different types of inhibitors in several different temporal combinations. The results from these studies and results reported elsewhere can be brought together into a consistent framework which combines the idea of autoregulation of histone biosynthesis as originally propose
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7

Sariban, E., R. S. Wu, L. C. Erickson, and W. M. Bonner. "Interrelationships of protein and DNA syntheses during replication of mammalian cells." Molecular and Cellular Biology 5, no. 6 (1985): 1279–86. http://dx.doi.org/10.1128/mcb.5.6.1279.

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During the replication of chromatin, the syntheses of the histone protein and DNA components are closely coordinated but not totally linked. The interrelationships of total protein synthesis, histone protein synthesis, DNA synthesis, and mRNA levels have been investigated in Chinese hamster ovary cells subjected to several different types of inhibitors in several different temporal combinations. The results from these studies and results reported elsewhere can be brought together into a consistent framework which combines the idea of autoregulation of histone biosynthesis as originally propose
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8

Turgay Tun, Turgay Tun, Nadir Demirel Nadir Demirel, Mahmut Emir Mahmut Emir, Asl han G. nel Asl han G nel, R. fk Kad o. lu R fk Kad o lu, and Nurcan Karacan Nurcan Karacan. "Three New Copper (II) Complexes with CHIRAL SCHIFF BASES: Synthesis, Characterization, DNA Binding and DNA-Cleavage Studies." Journal of the chemical society of pakistan 41, no. 2 (2019): 334. http://dx.doi.org/10.52568/000730/jcsp/41.02.2019.

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New mononuclear copper (II) complexes (1, 2 and 3) were synthesized from Schiff bases (H2L) of chiral amino alcohols. The structures of the copper complexes were proposed by a combination of elemental analyses, FTIR, LCMS, magnetic susceptibility and molar conductance measurement methods. Spectroscopic and analytical data of the complexes suggest four-coordinated structures. Geometry optimization carried out with DFT/6-31G (d,p) were proposed to be distorted square planar geometry for the complexes. The similarity between experimental and theoretical IR spectra confirms the proposed structures
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9

LUCK, DENNIS N., JOHNNY K. NGSEE, FRITZ M. ROTTMAN, and MICHAEL SMITH. "Synthesis of Bovine Prolactin inEscherichia coli." DNA 5, no. 1 (1986): 21–28. http://dx.doi.org/10.1089/dna.1986.5.21.

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Leslie, Mitch. "Double-checking DNA synthesis." Journal of Cell Biology 204, no. 2 (2014): 148. http://dx.doi.org/10.1083/jcb.2042iti1.

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Дисертації з теми "DNA Synthesis"

1

Lo, Allen Tak Yiu. "Protein dynamics on the lagging strand during DNA synthesis." Thesis, School of Chemistry, 2012. https://ro.uow.edu.au/theses/3684.

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DNA replication is one of the vital processes in the cell; it duplicates chromosomal DNA before a cell divides. In all organisms, DNA synthesis on the leading-strand template occurs continuously, whereas on the lagging strand a different mechanism is required. Due to the anti-parallel structure of double-stranded DNA, lagging-strand synthesis requires repeated RNA priming by a specialist primase and synthesis of short Okazaki fragments. How proteins carry out this dynamic process is still unknown. For Escherichia coli DNA replication, a lagging-strand three-point switch was proposed in 1999 to
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2

Lo, Pik Kwan Peggy. "Supramolecular DNA chemistry: assembly of DNA nanotubes and templated synthesis of DNA-mimetic polymers." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95152.

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DNA has emerged as a promising template for the programmable assembly of structures on the nanometer scale. In particular, DNA nanotubes hold promise for a number of biological and materials applications, because of their high aspect ratio and encapsulation potential. Current construction methods result in symmetrical and cylindrical assemblies that are totally double-stranded, and are long and polydisperse. In order to investigate DNA nanotubes for applications as well-defined molecular hosts and one-dimensional templates, better control over their geometry, stiffness and porosity, ability to
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3

Araki, Kasumi. "Dual roles for DNA polymerase η in homologous DNA recombination and translesion DNA synthesis". Kyoto University, 2006. http://hdl.handle.net/2433/143860.

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Porssa, Manuchehr. "Synthesis of radiosensitisers targeted to DNA." Thesis, Brunel University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305165.

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5

Ellsmore, Victoria. "Human cytomegalovirus origin-dependent DNA synthesis." Thesis, University of Glasgow, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340332.

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Devadoss, Babho. "Probing the Base Stacking Contributions During Translesion DNA Synthesis." Case Western Reserve University School of Graduate Studies / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=case1222818842.

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Roberts, Lezah Wilette. "The synthesis of a tetracene quinone phosphoramidite photosensitizer to study charge migration through DNA." Thesis, Georgia Institute of Technology, 2001. http://hdl.handle.net/1853/30903.

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Erler, Christiane. "Synthesis of Metallic Nanowires Using Integrated DNA Molecules as Templates." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-27671.

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The DNA double helix is inherently a nanoscale wire-like object, possessing a 2 nm diameter as well as a remarkable capability for molecular recognition and the interaction with other chemical compounds, thus making it an attractive material for biologically driven assembly of artificial nanostructures. In this work methods for the construction of functional electronic networks from single DNA molecules are presented. For this, (i) the generation of patterns of distinct interconnects between micro-fabricated contact pads are explored by stretching end-specifically thiol-functionalized, single-
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Stockley, Martin Lee. "Design and synthesis of selective DNA-dependent protein kinase (DNA-PK) inhibitors." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369816.

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Kapusuz, Derya. "Sol-gel Synthesis Of Dna Encapsulated Silica." Master's thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/2/12610627/index.pdf.

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Sol-gel processing routes for encapsulation of double stranded DNA in solid porous silica hosts have been established. The encapsulation was carried out in two steps: hydrolysis of a silica-forming alkoxide-based sol was followed by condensation/gelation to a solid form upon addition of a buffer solution containing DNA molecules. The effects of gelation chemistry and DNA amount on chemical and microstructural properties of resultant silica matrices and on DNA encapsulation efficiency were investigated. The analytical characterization was performed by UV-vis spectroscopy, 29Si nuclear magnetic
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Книги з теми "DNA Synthesis"

1

Campbell, Marissa J. DNA microarrays, synthesis, and synthetic DNA. Nova Science, 2011.

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2

Lilley, David M. J. 1948- and Dahlberg James, eds. DNA structures. Academic Press, 1992.

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3

A, Baker Tania, ed. DNA replication. 2nd ed. W.H. Freeman, 1992.

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4

Porssa, Manuchehr. Synthesis of radiosensitisers targeted to DNA. Brunel University, 1992.

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5

1943-, Erlich Henry A., ed. PCR technology: Principles and applications for DNA amplification. Macmillan Publishers, 1989.

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6

Hŏ, Tʻae-hoe. Chae chohap ŭiyakpʻum ŭi myŏnyŏgwŏnsŏng e kwanhan yŏnʼgu =: Study on immunogenicity of recombinant medicinal products. Sikpʻum Ŭiyakpʻum Anjŏnchʻŏng, 2007.

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7

E, Khudyakov Yury, and Fields Howard A, eds. Artificial DNA: Methods and applications. CRC Press, 2003.

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8

Adams, R. L. P. DNA replication. IRL Press, 1991.

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Arnold, Revzin, ed. The Biology of nonspecific DNA-protein interactions. CRC Press, 1990.

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10

Universitet, Stockholms, ed. Studies of bacteriophage P2 DNA replication functional characterisation of the initiation protein. Akademitryck AB, 1997.

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Частини книг з теми "DNA Synthesis"

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Engels, Joachim W., Belinda Sprunkel, and Eugen Uhlmann. "DNA Synthesis." In Biotechnology. Wiley-VCH Verlag GmbH, 2008. http://dx.doi.org/10.1002/9783527620838.ch9.

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2

Seeger, C., J. Summers, and W. S. Mason. "Viral DNA Synthesis." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76015-0_3.

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3

Nouri, Ali, and Christopher F. Chyba. "DNA Synthesis Security." In Methods in Molecular Biology. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-564-0_21.

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4

Masutani, Chikahide, and Fumio Hanaoka. "Translesion DNA Synthesis." In DNA Repair Disorders. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-6722-8_12.

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5

Rosen, Christian B., Thomas Tørring, and Kurt V. Gothelf. "DNA-Templated Synthesis." In Nucleic Acids and Molecular Biology. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38815-6_7.

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6

Mannocci, Luca. "DNA-encoded Chemical Libraries." In Diversity-Oriented Synthesis. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118618110.ch11.

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Little, Rachel C., Colette J. Whitfield, Eimer M. Tuite, and Andrew R. Pike. "The Synthesis of Designer DNA." In DNA Nanotechnology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8582-1_2.

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Kotlyar, Alexander. "Synthesis of DNA-Based Nanowires." In DNA Nanotechnology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8582-1_3.

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Loeb, L. A., and M. E. Reyland. "Fidelity of DNA Synthesis." In Nucleic Acids and Molecular Biology. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-46596-3_9.

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10

Hansen, Bjarke N., Kim S. Larsen, Daniel Merkle, and Alexei Mihalchuk. "DNA-Templated Synthesis Optimization." In Lecture Notes in Computer Science. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-66799-7_2.

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Тези доповідей конференцій з теми "DNA Synthesis"

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Zrihan, Amit, Eitan Yaakobi, and Zohar Yakhini. "Studying the Cycle Complexity of DNA Synthesis." In 2024 IEEE Information Theory Workshop (ITW). IEEE, 2024. https://doi.org/10.1109/itw61385.2024.10807020.

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Nguyen, Tuan Thanh, Kui Cai, and Kees A. Schouhamer Immink. "Efficient DNA Synthesis Codes with Error Correction and Runlength Limited Constraint." In 2024 IEEE International Symposium on Information Theory (ISIT). IEEE, 2024. http://dx.doi.org/10.1109/isit57864.2024.10619131.

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Abu-Sini, Maria, Andreas Lenz, and Eitan Yaakobi. "DNA Synthesis Using Shortmers." In 2023 IEEE International Symposium on Information Theory (ISIT). IEEE, 2023. http://dx.doi.org/10.1109/isit54713.2023.10206609.

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Makarychev, Konstantin, Miklos Z. Racz, Cyrus Rashtchian, and Sergey Yekhanin. "Batch Optimization for DNA Synthesis." In 2021 IEEE International Symposium on Information Theory (ISIT). IEEE, 2021. http://dx.doi.org/10.1109/isit45174.2021.9517820.

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Lenz, Andreas, Yi Liu, Cyrus Rashtchian, Paul H. Siegel, Antonia Wachter-Zeh, and Eitan Yaakobi. "Coding for Efficient DNA Synthesis." In 2020 IEEE International Symposium on Information Theory (ISIT). IEEE, 2020. http://dx.doi.org/10.1109/isit44484.2020.9174272.

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Vaníková, Zuzana, and Michal Hocek. "Polymerase synthesis of new photocaged DNA." In XVIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2014. http://dx.doi.org/10.1135/css201414392.

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Nguyen, Khoa, Stéphane Streiff, Sébastien Lyonnais, et al. "Synthesis of Palladium Conductive DNA-based Nanowires." In DNA-BASED NANOSCALE INTEGRATION: International Symposium on DNA-Based Nanoscale Integration. AIP, 2006. http://dx.doi.org/10.1063/1.2360585.

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An, H. T., S. Houchaimi, C. T. Burkhart, and M. J. Schertzer. "DNA Ligation on a Digital Microfluidic Device." In ASME 2020 18th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2020 Heat Transfer Summer Conference and the ASME 2020 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/icnmm2020-1028.

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Abstract This investigation demonstrates that digital microfluidic platforms are suitable for automated DNA ligation. Multiple DNA ligation steps are required to create DNA products using oligonucleotide synthesis. Unfortunately, traditional methods of oligonucleotide synthesis are unable to create highly accurate, long DNA products. This leads to a supply-side bottleneck that puts a drag on innovation in drug development, organism engineering, and agricultural improvement. Here we demonstrate ligation of two DNA products into one DNA product in digital microfluidic devices that manipulate dro
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Seela, Frank, Xiaohua Peng, Hong Li, et al. "Modified DNA: From synthesis to molecular recognition." In XIIIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2005. http://dx.doi.org/10.1135/css200507001.

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Erler, C., and M. Mertig. "Synthesis of metallic nanowire networks on DNA." In 2008 2nd Electronics Systemintegration Technology Conference. IEEE, 2008. http://dx.doi.org/10.1109/estc.2008.4684499.

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Звіти організацій з теми "DNA Synthesis"

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Mackelprang, Rebecca, ed. Security Screening in Synthetic DNA Synthesis: Recommendations for updated Federal Guidance. Engineering Biology Research Consortium, 2022. http://dx.doi.org/10.25498/e45p4v.

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Huntsman, Steven. Towards the Batch Synthesis of Long DNA. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada409078.

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Reif, John. Programme DNA Lattices: Design, Synthesis and Applications. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada447708.

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Mullet, J. E. Regulation of chloroplast number and DNA synthesis in higher plants. Final report. Office of Scientific and Technical Information (OSTI), 1995. http://dx.doi.org/10.2172/132689.

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Dervan, Peter B. Molecular Recognition of DNA. Synthesis of Novel Bases for Triple Helix Formation. Defense Technical Information Center, 1991. http://dx.doi.org/10.21236/ada278902.

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Mullet, J. E. Regulation of chloroplast number and DNA synthesis in higher plants. Final report. Office of Scientific and Technical Information (OSTI), 1995. http://dx.doi.org/10.2172/134990.

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Freeman, J. In vitro synthesis and purification of PhIP-deoxyguanosine and PhIP-DNA oligomer covalent complexes. Office of Scientific and Technical Information (OSTI), 1994. http://dx.doi.org/10.2172/98639.

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Mullet, J. E. Regulation of chloroplast number and DNA synthesis in higher plants. Final report, August 1995--August 1996. Office of Scientific and Technical Information (OSTI), 1997. http://dx.doi.org/10.2172/548678.

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Grafi, Gideon, and Brian Larkins. Endoreduplication in Maize Endosperm: An Approach for Increasing Crop Productivity. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7575285.bard.

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The focus of this research project is to investigate the role of endoreduplication in maize endosperm development and the extent to which this process contributes to high levels of starch and storage protein synthesis. Although endoreduplication has been widely observed in many cells and tissues, especially those with high levels of metabolic activity, the molecular mechanisms through which the cell cycle is altered to produce consecutive cycles of S-phase without an intervening M-phase are unknown. Our previous research has shown that changes in the expression of several cell cycle regulatory
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Weiser, Douglas C. The Role of GADD34 (Growth Arrest and DNA Damage-Inducible Protein) in Regulating Apoptosis, Proliferation, and Protein Synthesis in Human Breast Cancer Cells. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada427916.

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