Добірка наукової літератури з теми "Drugs Metabolism"
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Статті в журналах з теми "Drugs Metabolism"
Lambie, David G., and Ralph H. Johnson. "Drugs and Folate Metabolism." Drugs 30, no. 2 (August 1985): 145–55. http://dx.doi.org/10.2165/00003495-198530020-00003.
Повний текст джерелаDesouza, Cyrus, Mary Keebler, Dennis B. McNamara, and Vivian Fonseca. "Drugs Affecting Homocysteine Metabolism." Drugs 62, no. 4 (2002): 605–16. http://dx.doi.org/10.2165/00003495-200262040-00005.
Повний текст джерелаJann, Michael W., Y. W. Francis Lam, Eric C. Gray, and Wen-Ho Chang. "REVERSIBLE METABOLISM OF DRUGS." Drug Metabolism and Drug Interactions 11, no. 1 (January 1994): 1–24. http://dx.doi.org/10.1515/dmdi.1994.11.1.1.
Повний текст джерелаReiher, Jean. "Metabolism of Antiepileptic Drugs." Journal of Clinical Neurophysiology 2, no. 3 (July 1985): 309. http://dx.doi.org/10.1097/00004691-198507000-00007.
Повний текст джерелаFranceschini, Guido, and Rodolfo Paoletti. "Drugs controlling triglyceride metabolism." Medicinal Research Reviews 13, no. 2 (March 1993): 125–38. http://dx.doi.org/10.1002/med.2610130202.
Повний текст джерелаGhiselli, Giancarlo, and Marco Maccarana. "Drugs affecting glycosaminoglycan metabolism." Drug Discovery Today 21, no. 7 (July 2016): 1162–69. http://dx.doi.org/10.1016/j.drudis.2016.05.010.
Повний текст джерелаKostner, G. M. "Drugs affecting lipid metabolism." Chemistry and Physics of Lipids 51, no. 1 (July 1989): 73–74. http://dx.doi.org/10.1016/0009-3084(89)90068-6.
Повний текст джерелаDurrington, P. "Drugs Affecting Lipid Metabolism." International Journal of Cardiology 45, no. 2 (June 1994): 153–54. http://dx.doi.org/10.1016/0167-5273(94)90276-3.
Повний текст джерелаSitar, Daniel S. "Metabolism of Thioamide Antithyroid Drugs." Drug Metabolism Reviews 22, no. 5 (January 1990): 477–502. http://dx.doi.org/10.3109/03602539008991448.
Повний текст джерелаKelly, Patrick, and Barry Kahan. "Review: Metabolism of Immunosuppressant Drugs." Current Drug Metabolism 3, no. 3 (June 1, 2002): 275–87. http://dx.doi.org/10.2174/1389200023337630.
Повний текст джерелаДисертації з теми "Drugs Metabolism"
Bai, Shuang. "Effect of immunosuppressive agents on drug metabolism in rats." Thesis, Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3008270.
Повний текст джерелаBritt, Adrian John. "Cocaine metabolism in Pseudomonas maltophilia MB11L." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386328.
Повний текст джерела王漪雯 and Belinda Wong. "Haloperidol metabolism in man and animals." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1993. http://hub.hku.hk/bib/B3121194X.
Повний текст джерелаWong, Belinda. "Haloperidol metabolism in man and animals /." [Hong Kong] : University of Hong Kong, 1993. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13671546.
Повний текст джерелаDaneshmend, T. K. "Observations on presystemic metabolism of drugs in man." Thesis, University of Bristol, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.482894.
Повний текст джерелаPriston, Melanie Jane. "Studies on the pharmacokinetics and metabolism of mitozantrone." Thesis, University of Exeter, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303766.
Повний текст джерелаPereira, Maria J. "Effects of immunosuppressive drugs on human adipose tissue metabolism." Doctoral thesis, University of Gothenburg, 2012. http://hdl.handle.net/10400.1/4916.
Повний текст джерелаThe immunosuppressive agents (IAs) rapamycin, cyclosporin A and tacrolimus, as well as glucocorticoids are used to prevent rejection of transplanted organs and to treat autoimmune disorders. Despite their desired action on the immune system, these agents have serious longterm metabolic side-effects, including dyslipidemia and new onset diabetes mellitus after transplantation. The overall aim is to study the effects of IAs on human adipose tissue glucose and lipid metabolism, and to increase our understanding of the molecular mechanisms underlying the development of insulin resistance during immunosuppressive therapy. In Paper I and II, it was shown that rapamycin and the calcineurin inhibitors, cyclosporin A and tacrolimus, at therapeutic concentrations, had a concentration-dependent inhibitory effect on basal and insulin-stimulated glucose uptake in human subcutaneous and omental adipocytes. Rapamycin inhibited mammalian target of rapamycin complex (mTORC) 1 and 2 assembly and phosphorylation of protein kinase B (PKB) at Ser473 and of the PKB substrate AS160, and this leads to impaired insulin signalling (Paper I). On the other hand, cyclosporin A and tacrolimus had no effects on expression or phosphorylation of insulin signalling proteins (insulin receptor substrate 1 and 2, PKB, AS160), as well as the glucose transport proteins, GLUT4 and GLUT1 (Paper II). Instead, removal of GLUT4 from the cell surfasse was observed, probably mediated through increased endocytosis, as shown in L6 musclederived cells. These studies suggest a different mechanism for cyclosporin A and tacrolimus, in comparison to rapamycin, with respect to impairment of glucose uptake in adipocytes. In Paper III, all three IAs increased isoproterenol-stimulated lipolysis and enhanced phosphorylation of one of the main lipases involved in lipolysis, hormone-sensitive lipase. The agents also inhibited lipid storage, and tacrolimus and rapamycin down-regulated gene expression of lipogenic genes in adipose tissue. All three IAs increased interleukin-6 (IL-6), but not tumor necrosis factor α (TNF-α ) or adiponectin, gene expression and secretion. In Paper IV, we proposed that FKBP5 is a novel gene regulated by dexamethasone, a synthetic glucocorticoid, in both subcutaneous and omental adipose tissue. FKBP5 expression in subcutaneous adipose tissue is correlated with clinical and biochemical markers of insulin resistance and adiposity. In addition, the FKBP5 gene product was more abundant in omental than in subcutaneous adipose tissue. In conclusion, adverse effects of immunosuppressive drugs on human adipose tissue glucose and lipid metabolism can contribute to the development of insulin resistance, type 2 diabetes and dyslipidemia in patients on immunosuppressive therapy. The cellular mechanisms that are described in this thesis should be further explored in order to mitigate the metabolic perturbations caused by current immunosuppressive therapies. The findings in this thesis could potentially also provide novel pharmacological mechanisms for type 2 diabetes as well as other forms of diabetes.
Godwin, Bryan. "Discrete sliding mode control of drug infusions." Thesis, Georgia Institute of Technology, 1991. http://hdl.handle.net/1853/16806.
Повний текст джерелаBenchaoui, Hafid Abdelaali. "Factors affecting the pharmacokinetics, metabolism and efficacy of anthelmintic drugs." Thesis, University of Glasgow, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284569.
Повний текст джерелаNgulube, Thabale Jack. "The interaction of anti-malarial drugs and steroid hormone metabolism." Thesis, University of Leeds, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329825.
Повний текст джерелаКниги з теми "Drugs Metabolism"
Catapano, A. L., A. M. Gotto, Louis C. Smith, and Rodolfo Paoletti, eds. Drugs Affecting Lipid Metabolism. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1703-6.
Повний текст джерелаPaoletti, Rodolfo, David Kritchevsky, and William L. Holmes, eds. Drugs Affecting Lipid Metabolism. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71702-4.
Повний текст джерелаGotto, A. M., R. Paoletti, L. C. Smith, A. L. Catapano, and A. S. Jackson, eds. Drugs Affecting Lipid Metabolism. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0311-1.
Повний текст джерелаL, Catapano Alberico, and International Symposium on Drugs Affecting Lipid Metabolism, (11th : 1992 : Florence, Italy), eds. Drugs affecting lipid metabolism. Dordrecht: Kluwer Academic Publishers, 1993.
Знайти повний текст джерелаRodolfo, Paoletti, Kritchevsky David 1920-, Holmes William L. 1918-, and Drugs Affecting Lipid Metabolism Meeting (1986 : Florence, Italy), eds. Drugs affecting lipid metabolism. Berlin: Springer-Verlag, 1987.
Знайти повний текст джерелаGarth, Powis, ed. Anticancer drugs: Reactive metabolism and drug interactions. Oxford, England: Pergamon Press, 1994.
Знайти повний текст джерела1949-, Gibson G. Gordon, ed. Progress in drug metabolism. New York: John Wiley, 1988.
Знайти повний текст джерела1938-, Bieck Peter R., ed. Colonic drug absorption and metabolism. New York: M. Dekker, 1993.
Знайти повний текст джерелаKritchevsky, David, William L. Holmes, and Rodolfo Paoletti, eds. Drugs Affecting Lipid Metabolism VIII. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2459-1.
Повний текст джерелаInternational Symposium on Drugs Affecting Lipid Metabolism (8th 1983 Philadelphia, Pa.). Drugs affecting lipid metabolism VIII. New York: Plenum Press, 1985.
Знайти повний текст джерелаЧастини книг з теми "Drugs Metabolism"
Dwyer, B. E., and C. G. Wasterlain. "Intermediary Metabolism." In Antiepileptic Drugs, 79–100. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-69518-6_4.
Повний текст джерелаStene, Danny O., and Robert C. Murphy. "Metabolism of Sulfidopeptide Leukotrienes." In Prostanoids and Drugs, 37–46. New York, NY: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-7938-6_6.
Повний текст джерелаVuilhorgne, M., C. Gaillard, G. J. Sanderink, I. Royer, B. Monsarrat, J. Dubois, and M. Wright. "Metabolism of Taxoid Drugs." In ACS Symposium Series, 98–110. Washington, DC: American Chemical Society, 1994. http://dx.doi.org/10.1021/bk-1995-0583.ch007.
Повний текст джерелаTatum, William O. "Metabolism and Antiseizure Drugs." In Epilepsy Case Studies, 87–93. Cham: Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-01366-4_20.
Повний текст джерелаMeyer, Markus R., and Hans H. Maurer. "Drugs of Abuse (Including Designer Drugs)." In Metabolism of Drugs and Other Xenobiotics, 429–63. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527630905.ch16.
Повний текст джерелаRiedmaier, Stephan, and Ulrich M. Zanger. "Cardiovascular Drugs." In Metabolism of Drugs and Other Xenobiotics, 331–63. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527630905.ch12.
Повний текст джерелаSchwab, Matthias, Elke Schaeffeler, and Hiltrud Brauch. "Anticancer Drugs." In Metabolism of Drugs and Other Xenobiotics, 365–78. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527630905.ch13.
Повний текст джерелаKhojasteh, Siamak Cyrus, Harvey Wong, and Cornelis E. C. A. Hop. "Approved Drugs." In Drug Metabolism and Pharmacokinetics Quick Guide, 193–200. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-5629-3_11.
Повний текст джерелаMoore, Michael R., Kenneth E. L. McColl, Claude Rimington, and Abraham Goldberg. "Drugs, Chemicals, and Porphyria." In Disorders of Porphyrin Metabolism, 139–65. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-1277-2_5.
Повний текст джерелаChung, Y. L., and J. R. Griffiths. "Using Metabolomics to Monitor Anticancer Drugs." In Oncogenes Meet Metabolism, 55–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/2789_2008_089.
Повний текст джерелаТези доповідей конференцій з теми "Drugs Metabolism"
Ge, Xiaowei, Fátima C. Pereira, Yifan Zhu, Michael Wagner, and Ji-Xin Cheng. "Unveiling the impact of drug on single cell metabolism in human gut microbiome by an SRS-FISH platform." In Frontiers in Optics. Washington, D.C.: Optica Publishing Group, 2023. http://dx.doi.org/10.1364/fio.2023.fm6e.3.
Повний текст джерелаTourlomousis, Filippos, and Robert C. Chang. "2D and 3D Multiscale Computational Modeling of Dynamic Microorgan Devices as Drug Screening Platforms." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-52734.
Повний текст джерелаMrkalić, Emina, Marina Ćendić Serafinović, Ratomir Jelić, Stefan Stojanović, and Miroslav Sovrlić. "INFLUENCE OF QUERCETIN ON THE BINDING OF TIGECYCLINE TO HUMAN SERUM ALBUMIN." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.363m.
Повний текст джерелаPogodaeva, P. S. "Changes in the parameters of a clinical blood test in rats using hypoglycemic agents for the potentiation of drugs with a hepatoprotective effect." In SPbVetScience. FSBEI HE St. Petersburg SUVM, 2023. http://dx.doi.org/10.52419/3006-2023-11-28-34.
Повний текст джерелаRautiola, Davin, and Ronald A. Siegel. "Nasal Spray Device for Administration of Two-Part Drug Formulations." In 2019 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/dmd2019-3216.
Повний текст джерелаBešlo, Drago, Dejan Agić, Vesna Rastija, Maja Karnaš, Domagoj Šubarić, and Bono Lučić. "Analysis of prediction of water solubility and lipophilicity of coumarins by free cheminformatics tools." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.657d.
Повний текст джерелаAbduldayeva, Aigul, and Ainagul Kazbekova. "Dynamics of lipid metabolism in the combined therapy of antihypertensive and hypolipidemic drugs in patients with metabolic syndrome." In Diabetes Kongress 2023 - 57. Jahrestagung der DDG. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1767897.
Повний текст джерелаLei, Xiang-He, Shawn Noble, and Barry R. Bochner. "Abstract B42: Metabolic pathway changes induced by a PIK3 mutation and reverted by drugs." In Abstracts: AACR Special Conference: Metabolism and Cancer; June 7-10, 2015; Bellevue, WA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3125.metca15-b42.
Повний текст джерелаBing, Cheng, Guo Ke, Alex Wong, and Karen Crasta. "Abstract B59: Autophagy mediates senescence and supports survival upon treatment with anti-mitotic drugs." In Abstracts: AACR Special Conference: Metabolism and Cancer; June 7-10, 2015; Bellevue, WA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3125.metca15-b59.
Повний текст джерелаMa, Liang, Jeremy Barker, Changchun Zhou, Biaoyang Lin, and Wei Li. "A Perfused Two-Chamber System for Anticancer Drug Screening." In ASME 2010 International Manufacturing Science and Engineering Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/msec2010-34326.
Повний текст джерелаЗвіти організацій з теми "Drugs Metabolism"
Chipiso, Kudzanai. Biomimetic Tools in Oxidative Metabolism: Characterization of Reactive Metabolites from Antithyroid Drugs. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.3078.
Повний текст джерелаXiang, Kemeng, Huiming Hou, and Ming Zhou. The efficacy of Cerus and Cucumis Polypeptide injection combined with Bisphosphonates on postmenopausal women with osteoporosis:A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2022. http://dx.doi.org/10.37766/inplasy2022.5.0067.
Повний текст джерелаHawkins, David R. Determination of Drug Pharmacokinetics and Metabolic Profile. Volume 2. Fort Belvoir, VA: Defense Technical Information Center, March 1988. http://dx.doi.org/10.21236/ada192428.
Повний текст джерелаJin, Dachuan, Gao Peng, Shunqin Jin, Tao Zhou, Baoqiang Guo, and Guangming Li. Comparison of therapeutic effects of anti-diabetic drugs on non-alcoholic fatty liver disease patients without diabetes: A network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0014.
Повний текст джерелаHalim, Nader. Regulation of Brain Glucose Metabolic Patterns by Protein Phosphorlyation and Drug Therapy. Fort Belvoir, VA: Defense Technical Information Center, March 2007. http://dx.doi.org/10.21236/ad1013984.
Повний текст джерелаGhosal, Samit, and Binayak Sinha. The cardiovascular benefits of GLP1-RA are directly related to their positive effect on glycaemic control: A meta-regression analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2022. http://dx.doi.org/10.37766/inplasy2022.1.0071.
Повний текст джерелаLiu, Shuang, Zheng-Miao Wang, Dong-Mei Lv, and Yi-Xuan Zhao. Advances in highly active one-carbon metabolism in cancer diagnosis, treatment, and drug resistance: a systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0099.
Повний текст джерелаHu, Yang Yang, Xing Zhang, Yue Luo, and Yadong Wang. Systematic review and Meta analysis of the efficacy and safety of rifaximin in the prevention and treatment of hepatic encephalopathy. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2023. http://dx.doi.org/10.37766/inplasy2023.2.0061.
Повний текст джерелаCytryn, Eddie, Mark R. Liles, and Omer Frenkel. Mining multidrug-resistant desert soil bacteria for biocontrol activity and biologically-active compounds. United States Department of Agriculture, January 2014. http://dx.doi.org/10.32747/2014.7598174.bard.
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