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Статті в журналах з теми "FIGO IA"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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1

Medenwald, Daniel, Susan Langer, Cornelia Gottschick, and Dirk Vordermark. "Effect of Radiotherapy in Addition to Surgery in Early Stage Endometrial Cancer: A Population-Based Study." Cancers 12, no. 12 (2020): 3814. http://dx.doi.org/10.3390/cancers12123814.

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Background: The role of radiotherapy in the management of early (FIGO I) endometrial cancer is controversial with limited availability of prospective data from randomized trials. Methods: German Epidemiologic Cancer Registries provided by the Robert Koch Institute. We considered FIGO I cases with recorded operative treatment (n = 12,718, 2000–2017). We computed hazard ratios (HR) from relative survival models in relation to the mortality of the general population with 95% confidence intervals (CI). Multivariate models were adjusted for age, stage (IA vs. IB), grading, and chemotherapy. Radioth

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2

Dewayani, Birgitta M., Hasrayati Agustina, Desi Puspita, Bethy S. Hernowo, and Sri Suryanti. "Expression of CD133 and Aldehyde Dehydrogenase 1A1 in Borderline Ovarian Tumor and Their Correlation with International Federation of Gynecology and Obstetrics." Open Access Macedonian Journal of Medical Sciences 8, A (2020): 160–63. http://dx.doi.org/10.3889/oamjms.2020.3417.

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BACKGROUND: Borderline ovarian tumor (BOT) is an epithelial ovarian tumor with atypical epithelial proliferation without stromal invasion. BOTs may have an aggressive fashion with associated microinvasion feature, peritoneal “implants,” regional lymphadenopathy, and higher International Federation of Gynecology and Obstetrics (FIGO) stage. CD133 is cancer stem cells (CSCs) marker that promotes cell proliferation and tumor invasion through induction of nuclear factor kappa B and upregulation of MMP9. Aldehyde dehydrogenase 1A1 (ALDH1A1) is CSCs marker that promotes cell proliferation through th

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3

Seward, Shelly, Rouba Ali-Fehmi, Adnan R. Munkarah, et al. "Outcomes of Patients With Uterine Serous Carcinoma Using the Revised FIGO Staging System." International Journal of Gynecologic Cancer 22, no. 3 (2012): 452–56. http://dx.doi.org/10.1097/igc.0b013e31823de6dd.

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ObjectiveOur aim was to evaluate the prognostic significance of the revised 2009 International Federation of Gynecology and Obstetrics (FIGO) staging criteria in patients with uterine serous carcinoma (USC).Materials and MethodsWe retrieved clinical and histopathologic data on women with USC from 2 large academic centers. Age, race, stage, myometrial invasion, angiolymphatic invasion, and adjuvant therapy were analyzed using Kaplan-Meier and Cox regression models.ResultsA total of 168 patients were included. Three-year survival rate was 81% for revised stage I, 52% for stage II, 46% for stage

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4

Abu-Rustum, Nadeem R., Qin Zhou, Alexia Iasonos, et al. "The Revised 2009 FIGO Staging System for Endometrial Cancer: Should the 1988 FIGO Stages IA and IB Be Altered?" International Journal of Gynecologic Cancer 21, no. 3 (2011): 511–16. http://dx.doi.org/10.1097/igc.0b013e31820cc305.

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ObjectivesThe revised 2009 International Federation of Gynecology and Obstetrics (FIGO) staging system for endometrial cancer included many changes over the 1988 system, particularly for stage I subgroups. We sought to describe the overall survival (OS) of women with stage I endometrial cancer and examine how the estimated stage-specific OS is altered in the 2009 system.MethodsA prospectively maintained institutional endometrial database was analyzed. All patients underwent primary surgery between January 1993 and June 2009.ResultsData from 1658 women were analyzed, including 1307 patients wit

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5

Vésale, Elie, Henri Azaïs, Jérémie Belghiti, Maryam Nikpayam, Catherine Uzan, and Geoffroy Canlorbe. "How to perform a laparoscopic pelvic sentinel lymph node dissection using near-infrared fluorescence with indocyanine green in gynecological cancers." International Journal of Gynecologic Cancer 29, no. 2 (2019): 443. http://dx.doi.org/10.1136/ijgc-2018-000074.

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The role of pelvic sentinel lymph node dissection (SLND) is increasing in oncological pelvic surgery, especially in the management of cervical and endometrial cancer.SLND using indocyanine green (ICG) is safe and effective, and its sensitivity is higher than with other detection methods. The advantages of ICG are its low toxicity, its confinement within the vascular compartment, its rapid excretion, and the rarity of allergic reaction. These advantages confer to this fluorescent dye a superiority over blue, which can cause anaphylactic reactions. Using ICG does not require advance planning inv

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6

Chinczewski, Lukas, Dario Zocholl, Alexandra Wagner, Radoslav Chekerov, Elena Ioana Braicu, and Jalid Sehouli. "Real world evidence on long-term survival of patients with endometrial cancer in Germany: Analysis of population-based cancer registry data on 49808 women." Journal of Clinical Oncology 41, no. 16_suppl (2023): e17623-e17623. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e17623.

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e17623 Background: Endometrial cancer (EC) is the most common gynecological cancer worldwide. The understanding of clinicopathological characteristics has changed within the last years. Limited data are available regarding the long-term survival of EC patients. Methods: Clinical data and survival data for patients with EC diagnosed in Germany between 2010 and 2020 were gathered from the German national center for population-based cancer registry. Differentiated by histological subtype, 5- and 7-year survival rates were calculated. Results: 49,808 patients with newly diagnosed EC between 2010 a

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7

Hricak, Hedvig, Constantine Gatsonis, Dennis S. Chi, et al. "Role of Imaging in Pretreatment Evaluation of Early Invasive Cervical Cancer: Results of the Intergroup Study American College of Radiology Imaging Network 6651–Gynecologic Oncology Group 183." Journal of Clinical Oncology 23, no. 36 (2005): 9329–37. http://dx.doi.org/10.1200/jco.2005.02.0354.

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Purpose To compare magnetic resonance imaging (MRI) and computed tomography (CT) with each other and to International Federation of Gynecology and Obstetrics (FIGO) clinical staging in the pretreatment evaluation of early invasive cervical cancer, using surgicopathologic findings as the reference standard. Patients and Methods This prospective multicenter clinical study was conducted by the American College of Radiology Imaging Network and the Gynecologic Oncology Group from March 2000 to November 2002; 25 United States health centers enrolled 208 consecutive patients with biopsy-confirmed cer

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8

de Gregorio, Nikolaus, Amelie De Gregorio, Florian Ebner, et al. "Influence of the new FIGO classification for cervical cancer on patients’ survival: Retrospective analysis of 265 histologically confirmed cases with FIGO stages Ia to IIb." Journal of Clinical Oncology 37, no. 15_suppl (2019): e17006-e17006. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e17006.

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e17006 Background: End of 2018 a new FIGO Classification for cervical cancer was published, mainly revising stage Ib and introducing a new stage IIIc, which includes irrespectively of tumor size and local spread all patients with lymph node metastasis. Methods: We retrospectively analyzed all cases of cervical cancer stage I to IIb who underwent surgery as primary treatment at our institution from 2000 until 2016 and therefore had a histological confirmation of tumor stage. We reclassified all histologies according to the new FIGO classification and calculated outcome parameters according to t

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9

Tsolakidis, Dimitrios, Dimitrios Zouzoulas, Iliana Sofianou, et al. "External Validation of the New 2023 International Federation of Gynecology and Obstetrics Staging System in Endometrial Cancer Patients: 12-Year Experience from an European Society of Gynecological Oncology-Accredited Center." Medicina 60, no. 9 (2024): 1421. http://dx.doi.org/10.3390/medicina60091421.

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Background and Objectives: The new molecular classification of endometrial cancer continuously changes the management of the disease in everyday clinical practice. Recently, FIGO released a new staging system for endometrial cancer, which incorporates molecular substages and subdivides further early-stage disease. The aim of this study was to investigate the differences between the two FIGO staging systems and evaluate the prognostic precision of the new one. Materials and Methods: We retrospectively analyzed the records of patients with endometrial cancer that were fully treated in the 1st De

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10

Zhang, Weifeng, Chunlin Chen, Ping Liu, et al. "Staging early cervical cancer in China: data from a multicenter collaborative." International Journal of Gynecologic Cancer 29, no. 5 (2019): 869–73. http://dx.doi.org/10.1136/ijgc-2019-000263.

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BackgroundIn 2018 the International Federation of Gynecology and Obstetrics (FIGO) revised the staging system of cervical cancer. This study aimed to assess the quality of staging early cervical cancer in China before the revision.MethodsThis multicenter retrospective study included 34 tertiary hospitals in China. Medical records of patients with cervical cancer who underwent primary surgical treatment between January 2010 and December 2015 were reviewed retrospectively. All patients were clinically staged according to the 2009 FIGO staging system. Eligibility criteria included: histopathologi

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11

Asaithambi, Shubha Supriya, Shruthi Swamy, Shashidhar V. Karpurmath, Manjunath Nandennavar, and Veerendra Angadi. "Synchronous ovarian granulosa cell tumor and carcinoma endometrium due to excess estrogen secretion: a rare presentation." International Journal of Research in Medical Sciences 13, no. 1 (2024): 445–49. https://doi.org/10.18203/2320-6012.ijrms20244154.

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Granulosa cell tumor (GCT) is a low malignant potential ovarian tumor accounting for 70% of all sex cord stromal tumor. It is an estrogen secreting tumor, hence diagnosed in early stages, associated with 20-30% concomitant lesion in endometrium including 5% of invasive adenocarcinoma. Through this case report we present the synchronous occurrence of ovarian and endometrial malignancy of a 52-year-old female, P3L2A0 who presented with irregular menstrual bleeding since 2 months along with literature review. Imaging showed endometrial lesion with synchronous left ovarian lesion with a normal CA-

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12

Burghardt, E., A. Östör, and H. Fox. "The New FIGO Definition of Cervical Cancer Stage IA: A Critique." Gynecologic Oncology 65, no. 1 (1997): 1–5. http://dx.doi.org/10.1006/gyno.1997.4672.

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13

Zhan, Xiangbo, Lei Li, Ming Wu, and Jinghe Lang. "The prognosis of stage IA synchronous endometrial endometrioid and ovarian carcinomas." Archives of Gynecology and Obstetrics 300, no. 4 (2019): 1045–52. http://dx.doi.org/10.1007/s00404-019-05288-5.

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Abstract Introduction Little is known about the prevalence and prognosis of synchronous endometrial and ovarian carcinomas. This report explores the survival outcomes of synchronous stage IA endometrioid endometrial and stage IA ovarian carcinomas in a retrospective cohort study. Methods All cases of pathological confirmed synchronous stage IA endometrial endometrioid and ovarian carcinomas from June 1, 2010, to June 1, 2017, in a teaching hospital were reviewed. Patients were followed up to February 1, 2019. Survival outcomes were compared between patients with and without synchronous carcino

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14

Tan, Jason, Naven Chetty, Srinivas Kondalsamy-Chennakesavan, et al. "Validation of the FIGO 2009 Staging System for Carcinoma of the Vulva." International Journal of Gynecologic Cancer 22, no. 3 (2012): 498–502. http://dx.doi.org/10.1097/igc.0b013e318241d994.

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BackgroundThe previous (1988) International Federation of Gynecology and Obstetrics (FIGO) vulval cancer staging system failed in 3 important areas: (1) stage 1 and 2 disease showed similar survival; (2) stage 3 represented a most heterogeneous group of patients with a wide survival range; and (3) the number and morphology of positive nodes were not taken into account.ObjectiveTo compare the 1988 FIGO vulval carcinoma staging system with that of 2009 with regard to stage migration and prognostication.MethodsInformation on all patients treated for vulval cancer at the Queensland Centre for Gyne

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15

Lyubchenko, L. N., S. V. Mukhtarulina, M. A. Meshkova, Z. A. Sidakova, N. N. Volchenko, and E. G. Novikova. "Molecular genetic classification of endometrial cancer in the context of personalised medicine." Advances in Molecular Oncology 12, no. 2 (2025): 35–46. https://doi.org/10.17650/2313-805x-2025-12-2-35-46.

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The article presents a new classification of endometrial cancer developed by the International Federation of Gynecology and Obstetrics (FIGO): FIGO 2023. Literature search was performed in the PubMed, Medline, RSCI (Russian Science Citation Index) databases using key words “endometrial cancer”, “molecular genetic study”, “FIGO 2023”, “POLE gene mutations”, “dMMR status”, “ТР53 gene”, “NSMP”. In total, 206 articles were found (published between 1983 and 2024), the more significant articles (45) were included in this literature review. The renewed FIGO 2023 classification contains 19 endometrial

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16

Gutnik, Helena, Jasenka P. Matisic, Maja Primic Zakelj, and Margareta Strojan Flezar. "Microinvasive cervical squamous cell carcinoma in Slovenia during the period 2001-2007." Radiology and Oncology 48, no. 3 (2014): 282–88. http://dx.doi.org/10.2478/raon-2014-0010.

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Abstract Background. Microinvasive squamous cell carcinoma (MISCC) comprises a significant portion of all cervical cancers in Slovenia. Criteria of carcinomatous invasion are well described in the literature, however histopathological assessment of MISCC is difficult, because morphological characteristics can overlap with cervical intraepithelial neoplasia grade 3 (CIN 3) and other pathological changes. The aim of our study was to evaluate the reliability of the histopathological diagnosis of MISCC in Slovenia during the period from 2001 to 2007. Materials and methods. Data on patients with a

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17

Cucinella, Giuseppe, Maryam Shahi, Amy Weaver, et al. "Prognosis of surgically staged FIGO IA uterine carcinosarcoma without myometrial invasion (503)." Gynecologic Oncology 166 (August 2022): S248. http://dx.doi.org/10.1016/s0090-8258(22)01725-5.

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18

Myers, Andrea, William T. Barry, Michelle S. Hirsch, Ursula Matulonis та Larissa Lee. "β-Catenin mutations in recurrent FIGO IA grade I endometrioid endometrial cancers". Gynecologic Oncology 134, № 2 (2014): 426–27. http://dx.doi.org/10.1016/j.ygyno.2014.06.010.

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19

Tsukamoto, Naoki, Tunehisa Kaku, Keita Matsukuma, et al. "The problem of stage Ia (FIGO, 1985) carcinoma of the uterine cervix." Gynecologic Oncology 34, no. 1 (1989): 1–6. http://dx.doi.org/10.1016/0090-8258(89)90094-2.

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20

Kinikanwo, Green, Mkpe Abbey, and George M. Ela. "Intermittent auscultation in obstetric practice in tertiary health facilities in Nigeria. Are we doing it correctly?" International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 1 (2021): 7. http://dx.doi.org/10.18203/2320-1770.ijrcog20215069.

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Background: Intermittent auscultation (IA) was the main method of foetal monitoring in Nigeria, with the pinard stethoscope more in use than the hand-held Doppler. Aim of the study to produce a guideline on IA, conduct an audit on its use and to give a recommendation for future practice. Methods: A mixed-method design-observational-descriptive, review and an audit carried out in tertiary centres in Rivers State, Nigeria. The WHO 2018, FIGO 2015 and other guidelines on IA were reviewed. Good practice points were extracted from the literatures and used to produce a guideline. 17 review criteria

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21

Zheng, Ziyu, Ye Liu, Longxiang Feng, et al. "Multimodal MRI Image Fusion for Early Automatic Staging of Endometrial Cancer." Sensors 25, no. 9 (2025): 2932. https://doi.org/10.3390/s25092932.

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This magnetic resonance imaging multimodal fusion study aims to automate the staging of endometrial cancer using deep learning and to compare the diagnostic performance of deep learning with that of radiologists in the staging of endometrial cancer. This study retrospectively investigated 122 patients with pathologically confirmed early EC from January 1, 2025 to December 31, 2021. Of these patients, 68 were in the International Federation of Gynecology and Obstetrics (FIGO) stage IA, and 54 were in FIGO stage IB. Based on the Swin transformer model and its proprietary SW-MSA (shift window mul

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22

Grimm, Christoph, Alexander Reinthaller, Gerda Hofstetter, Nicole Concin, Christian Marth, and Stephan Polterauer. "Nomogram prediction for overall survival of patients diagnosed with cervical cancer." Journal of Clinical Oncology 30, no. 15_suppl (2012): 5111. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.5111.

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5111 Background: Cervical cancer is clinically staged based upon the International Federation of Gynecologists and Obstetricians (FIGO) system. FIGO stage is well established as prognostic parameter. It is well known that other additional parameters are useful to estimate overall survival (OS) in patients with cervical cancer. The aim of this multi-center was to create a nomogram to predict OS in patients diagnosed with cervical cancer. Methods: Cervical cancer databases of two large Austrian institutions were analysed. Characteristics known to predict OS were collected. For each patient assoc

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23

Pietrus, Milosz, Kazimierz Pitynski, Marcin Waligora, et al. "CD133 Expression in the Nucleus Is Associated with Endometrial Carcinoma Staging and Tumor Angioinvasion." Journal of Clinical Medicine 10, no. 10 (2021): 2144. http://dx.doi.org/10.3390/jcm10102144.

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Background: (1) Endometrial cancer is one of the most common cancers affecting women, with a growing incidence. To better understand the different behaviors associated with endometrial cancer, it is necessary to understand the changes that occur at a molecular level. CD133 is one of the factors that regulate tumor progression, which is primarily known as the transmembrane glycoprotein associated with tumor progression or cancer stem cells. The aim of our study was to assess the impact of subcellular CD133 expression on the clinical course of endometrial cancer. (2) Methods: CD133 expression in

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24

Cisek, Paweł, Dariusz Kieszko, Izabela Kordzińska-Cisek, Elżbieta Kutarska, and Ludmiła Grzybowska-Szatkowska. "Retrospective Analysis of Intravaginal Brachytherapy in Adjuvant Treatment of Early Endometrial Cancer." BioMed Research International 2018 (2018): 1–9. http://dx.doi.org/10.1155/2018/7924153.

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The aim of this study was to determine the role of adjuvant endovaginal brachytherapy HDR (High Dose Rate) or observation, as well as identification of risk factors of tumor recurrence. The study included 178 women after radical hysterectomy. All patients belonged to the group of low- and medium-risk stage I FIGO. Analysis consisted of 3-, 5-, and 10-year OS, DFS, and LRFS in both groups. Follow-up was more than 6.5 years. The 5-OS, 5-DFS, and 5-LRFS were 93%, 96%, and 98% in the treated group and 95%, 94%, and 96% in the observed group, respectively. These differences were not statistically s

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25

Skirnisdóttir, I., B. Sorbe, and T. Seidal. "P53, bcl-2, and bax: Their relationship and effect on prognosis in early stage epithelial ovarian carcinoma." International Journal of Gynecologic Cancer 11, no. 2 (2001): 147–58. http://dx.doi.org/10.1136/ijgc-00009577-200103000-00009.

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The prognosis of ovarian carcinoma, even in the early stages (FIGO I–II), continues to present a challenge despite advances in the understanding of pathophysiology and treatment. In a series of 106 patients with epithelial carcinomas in FIGO stages IA–IIC, a number of prognostic factors (age, FIGO stage, histopathologic type, and tumor grade) were studied in relation to important regulators of apoptosis (p53, bcl-2, and bax). Immunohistochemical techniques were used. All the patients received adjuvant radiotherapy after the primary surgery. Univariate analysis showed that expression of p53 was

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26

Shih, Ying-Chu, I.-Chia Lin, and Peng-Hui Wang. "Hysteroscopic resection for women with FIGO IA grade 1 endometrioid-type endometrial cancer." Taiwanese Journal of Obstetrics and Gynecology 58, no. 2 (2019): 304–5. http://dx.doi.org/10.1016/j.tjog.2019.02.004.

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27

Hollis, Robert L., Lorna J. Stillie, Samantha Hopkins, et al. "Clinicopathological Determinants of Recurrence Risk and Survival in Mucinous Ovarian Carcinoma." Cancers 13, no. 22 (2021): 5839. http://dx.doi.org/10.3390/cancers13225839.

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Mucinous ovarian carcinoma (MOC) is a unique form of ovarian cancer. MOC typically presents at early stage but demonstrates intrinsic chemoresistance; treatment of advanced-stage and relapsed disease is therefore challenging. We harness a large retrospective MOC cohort to identify factors associated with recurrence risk and survival. A total of 151 MOC patients were included. The 5 year disease-specific survival (DSS) was 84.5%. Risk of subsequent recurrence after a disease-free period of 2 and 5 years was low (8.3% and 5.6% over the next 10 years). The majority of cases were FIGO stage I (35.

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Viveros-Carreño, David, Juliana Rodriguez, and Rene Pareja. "Incidence of metastasis in circumflex iliac nodes in patients with cervical cancer: a systematic review." International Journal of Gynecologic Cancer 31, no. 12 (2021): 1530–34. http://dx.doi.org/10.1136/ijgc-2021-003005.

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ObjectiveThe circumflex iliac nodes distal to the external iliac nodes are frequently removed when bilateral pelvic lymphadenectomy is performed in patients with cervical cancer. The objective of this systematic review was to assess the incidence of metastasis in the circumflex iliac nodes in patients with cervical cancer.MethodsPubMed/Medline, ClinicalTrials, Embase, Cochrane Central Register of Controlled Trials, Scopus, and Ovid databases were searched from inception to May 2021. We included articles published in English language reporting all types of studies, except for case reports and c

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Abbey, Mkpe, and Kinikanwo I. Green. "Admission cardiotocography versus Doppler auscultation of fetal heart in high risk pregnancies in a tertiary health facility in Nigeria." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 9 (2021): 3268. http://dx.doi.org/10.18203/2320-1770.ijrcog20213439.

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Background: Admission cardiotocography (CTG) and intermittent auscultation (IA) of the fetal heart might help to identify those foetuses that could not withstand the stress of labour and also predict neonatal outcome. The aim was to compare the associations of admission CTG findings and those of IA of the fetal heart with labour and neonatal outcome.Methods: It was a prospective COHORT study. 30 minutes admission CTG for each of the 387 participants was interpreted, using the FIGO 2015 guideline and physiological interpretation. Admission IA was also performed on the same patients. Women whose

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Pan, Shuya, Wenxiao Jiang, Shangdan Xie, Haiyan Zhu, and Xueqiong Zhu. "Clinicopathological Features and Survival of Adolescent and Young Adults with Cervical Cancer." Cancer Control 28 (January 2021): 107327482110515. http://dx.doi.org/10.1177/10732748211051558.

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Purpose To explore clinicopathological characteristics and their prognostic value among young patients with cervical cancer (who are aged ≤25 years old). Methods The Surveillance, Epidemiology, and End Results Program (SEER) database was used to extract data on cervical cancer patients. They were then stratified by age as young women (≤25 years old) and old women (26–35 years old) and analyzed for clinicopathology characteristics and treatment modalities. Prognosis was analyzed using Kaplan–Meier survival curve, as well as hazard ratios using Cox regression modeling. The nomogram was developed

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Balaya, Vincent, Benedetta Guani, Laurent Magaud, et al. "Long-term oncological safety of sentinel lymph node biopsy in early-stage cervical cancer." Journal of Clinical Oncology 38, no. 15_suppl (2020): 6006. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.6006.

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6006 Background: The goal of this study was to assess disease-free survival (DFS) and disease-specific survival (DSS) in patients with early-stage cervical cancer who underwent bilateral sentinel lymph node (BSLN) biopsy alone versus bilateral pelvic lymphadenectomy (BPL). Methods: An ancillary analysis of two prospective multicentric trials on SLN biopsy for cervical cancer (SENTICOL I and II) was performed. All patients with early stage cervical cancer (IA to IIB FIGO stage), negative SLN after ultrastaging and negative non-SLN after final pathologic examination were included. Risk-factors o

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Babarović, Emina, Ivan Franin, Marko Klarić, et al. "Adult Granulosa Cell Tumors of the Ovary: A Retrospective Study of 36 FIGO Stage I Cases with Emphasis on Prognostic Pathohistological Features." Analytical Cellular Pathology 2018 (August 16, 2018): 1–11. http://dx.doi.org/10.1155/2018/9148124.

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Objective. Adult granulosa cell tumors (AGCTs) represent 2%–5% of all ovarian malignancies. The aim of this study was to analyze clinical and pathohistological parameters and their impact on recurrence, overall, and disease-free survival in FIGO stage I AGCT patients. Methods. The tumor specimens analyzed in this retrospective study were obtained from a total of 36 patients with diagnosis of ovarian AGCT surgically treated at the Department of Gynecology, Rijeka University Hospital Centre, between 1994 and 2012. Clinical, pathological, and follow-up data were collected. Results. The mean age a

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Nasioudis, Dimitrios, Melissa K. Frey, Eloise Chapman-Davis, Thomas A. Caputo, and Kevin M. Holcomb. "Surveillance Only for High-risk FIGO Stage IA/IB Malignant Ovarian Germ Cell Tumors." American Journal of Clinical Oncology 44, no. 5 (2021): 195–99. http://dx.doi.org/10.1097/coc.0000000000000805.

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KLAT, JAROSLAV, ALES MLADENKA, JANA DVORACKOVA, SYLVA BAJSOVA, and ONDREJ SIMETKA. "L1CAM as a Negative Prognostic Factor in Endometrioid Endometrial Adenocarcinoma FIGO Stage IA-IB." Anticancer Research 39, no. 1 (2018): 421–24. http://dx.doi.org/10.21873/anticanres.13128.

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Feng, Ying, Zihan Zhang, Tong Lou, Shuzhen Wang, Huimin Bai, and Zhenyu Zhang. "The Safety of RT for the Management of FIGO Stages IA-IIA Cervical Cancer." Obstetrics & Gynecology 131 (May 2018): 191S. http://dx.doi.org/10.1097/01.aog.0000533239.64830.7b.

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Badesara, Sanjay, Ashitha R. Gangadharan, Rambeer Singh, and Adarsh Dharmarajan. "Re-staging surgery in endometrial cancer: an audit on its value." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 12 (2020): 4898. http://dx.doi.org/10.18203/2320-1770.ijrcog20204969.

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Background: Incomplete surgical staging in carcinoma endometrium is not an uncommon entity in developing world. Proper surgical staging has got a role in prognostication and planning adjuvant treatment. So, an audit was done to assess the extent of upstaging in women with endometrial cancers who were referred to index centre from outside hospitals with incomplete surgical staging.Methods: It is a retrospective study. The demographic, clinical and treatment details of women with complete data having at-least one follow up after completion surgery were analyzed. Patients who had any other antica

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Skirnisdóttir, I., B. Sorbe, and T. Seidal. "The growth factor receptors HER-2/neu and EGFR, their relationship, and their effects on the prognosis in early stage (FIGO I-II) epithelial ovarian carcinoma." International Journal of Gynecologic Cancer 11, no. 2 (2001): 119–29. http://dx.doi.org/10.1136/ijgc-00009577-200103000-00005.

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Epithelial ovarian cancer is a heterogeneous disease and many biologic and molecular factors are important for its development and progression, including growth rate, metastatic potential, chemo- and radiosensitivity, and prognosis. Even in the early stages (FIGO I–II), many questions persist about the biologic behavior, optimal treatment, and prognosis.In a series of 106 patients with epithelial ovarian cancers in FIGO stages IA-IIC, a number of known prognostic factors (age, FIGO stage, histopathologic type, and tumor grade) were studied in relation to two important growth factor receptors f

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Rogers, Linda J., and David M. Luesley. "Stage IA2 Cervical Carcinoma: How Much Treatment Is Enough?" International Journal of Gynecologic Cancer 19, no. 9 (2009): 1620–24. http://dx.doi.org/10.1111/igc.0b013e3181a446b3.

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Objective:The current guidance for the management of women with stage IA2 cervical carcinoma is that whatever the primary surgical intervention, pelvic lymphadenectomy should be included. The role of lymphadenectomy in the management of cervical carcinoma remains somewhat confused, as the procedure has not been proven to be therapeutic, although it is claimed that the information gained is valuable in determining the need for adjuvant therapy.For lymphadenectomy to have clinical utility in the care of women with stage IA2 cervical carcinoma, a sufficiently high incidence of node positivity wou

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Ilic, Milena, Dalibor Jovanovic, Milos Milosavljevic, et al. "Hypercalcemic type of small cell carcinoma of the ovary." Vojnosanitetski pregled 72, no. 3 (2015): 295–98. http://dx.doi.org/10.2298/vsp1503295i.

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Introduction. Extrapulmonary small cell carcinoma is a rare, prognostically bad tumor category. Primary, it can be localized in every organ, even in the ovary, where, due to its clinical specificities, it represents a challenge in diagnosis, as well as in therapy. Small cell ovarian carcinoma (SCOC) is biologically very aggressive malignant tumor of unknown histogenesis. We presented a rare case of SCOC with hypercalcemia of aggressive course and fatal outcome in a postmenopausal woman at International Federation of Gynecology and Obstetrics (FIGO) Ia stage. Case report. A 60-year-old woman, C

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Sugimori, H., T. Kawarabayashi, T. Iwasaka, K. Fukuda, T. Hachisuga, and Y. Hayashi. "Colposcopic assessment of stage I cervical cancer." International Journal of Gynecologic Cancer 1, no. 4 (1991): 179–83. http://dx.doi.org/10.1046/j.1525-1438.1991.01040179.x.

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A differential assessment by colposcopy of three subgroups of stage I in the new FIGO classification of cervical cancer was attempted. Colposcopic findings in invasive cancer were atypical white epithelium, atypical mosaic, papillary punctation, atypical vessels, abnormal ‘rock-like’ projection, papillomatous growth and ulcer. Ulcer and abnormal ‘rock-like’ projection were more suggestive of a frank invasive carcinoma than a microinvasive carcinoma. While 89% of the cases in stage Ib were correctly predicted, only about 50% of those in stage Ia were correctly predicted. We propose that a colpo

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Ree, Y. S., S. H. Cho, S. R. Kim, S. H. Cho, K. T. Kim, and M. H. Park. "Synchronous primary endometrial and ovarian cancer with three different histologic patterns: A case report." International Journal of Gynecologic Cancer 13, no. 5 (2003): 678–82. http://dx.doi.org/10.1136/ijgc-00009577-200309000-00017.

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Synchronous cancers involving both endometrium and ovary in the female genital tract is a well-recognized phenomenon. However, most of them are metastatic lesions arising from one organ and simultaneous primary cancer occurring in both organs is relatively rare. We report a case with dual primary cancer occurring in both ovaries and endometrium with three different histologies. Recently, a 46-year-old women presented with vaginal bleeding was found to have FIGO stage IC clear cell carcinoma of the left ovary, stage IA borderline mucinous cystadoma of the right ovary, and stage IB endometrial c

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Chung, H. H., S. Y. Hwang, K. W. Jung, et al. "Ovarian cancer incidence and survival in Korea: 1993–2002." International Journal of Gynecologic Cancer 17, no. 3 (2007): 595–600. http://dx.doi.org/10.1136/ijgc-00009577-200705000-00007.

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This study examined incidence rates, histologic and stage distribution, and long-term survival rates of patients with ovarian cancer in Korea. A total of 11,404 patients diagnosed with ovarian cancer between 1993 and 2002 were reported to the Korea Central Cancer Registry and the Gynecologic Oncology Committee of Korean Society of Obstetrics and Gynecology. All rates were expressed per 100,000. The age-standardized incidence rates were 3.79 and 4.74 per 100,000 women in 1993 and 2002, respectively. The incidence rates of ovary cancer increased with age in Korea, and over half of the patients w

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Ly, D., B. D. Rowley, M. K. Dodson, A. P. Soisson, C. Jolles, and W. T. Sause. "Adjuvant radiation for high grade histology, early stage (FIGO IA) endometrial cancer improves local control." Gynecologic Oncology 131, no. 1 (2013): 264–65. http://dx.doi.org/10.1016/j.ygyno.2013.07.047.

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K., Varghese Mathew, Raphael Jomon C., Antony Febin, Mohan Malini, and Gopu Paul. "Efficacy of vaginal dilator use in preventing vaginal stenosis among cervical and endometrial cancer patients underwent radiotherapy." International Journal of Research in Medical Sciences 9, no. 4 (2021): 1034. http://dx.doi.org/10.18203/2320-6012.ijrms20211346.

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Background: Vaginal dilators (VD) are effective in the prevention of vaginal stenosis in patients undergoing pelvic radiotherapy for gynaecological malignancies. This study was aimed to assess the efficacy of VD use in preventing post radiotherapy vaginal stenosis in cervical and endometrial cancer patients.Methods: A cohort study was designed among patients (20-70 years) with biopsy proven endometrial and cervical carcinoma who underwent pelvic radiotherapy were included. Patients with cervical carcinoma (FIGO stage-IA to IVA), endometrial carcinoma (FIGO stage IB grade III, FIGO stage II), h

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Giuntoli, Robert L., Collette R. Lessard-Anderson, Melissa A. Gerardi, et al. "Comparison of Current Staging Systems and a Novel Staging System for Uterine Leiomyosarcoma." International Journal of Gynecologic Cancer 23, no. 5 (2013): 869–76. http://dx.doi.org/10.1097/igc.0b013e3182916a1e.

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ObjectivesUterine leiomyosarcoma (LMS) was traditionally staged by modified 1988 International Federation of Gynecology and Obstetrics (FIGO) staging criteria for endometrial adenocarcinoma. Contemporary methods of staging include the 2009 FIGO system for uterine LMS and the 2010 American Joint Committee on Cancer (AJCC) soft tissue sarcoma system. The aim of this study was to compare the accuracy of these 3 staging systems and a novel system in predicting disease-specific survival for patients with uterine LMS.MethodsPatients, evaluated at our institution with uterine LMS from 1976 to 2009, w

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Skírnisdóttir, I., T. Seidal, and B. Sorbe. "A new prognostic model comprising p53, EGFR, and tumor grade in early stage epithelial ovarian carcinoma and avoiding the problem of inaccurate surgical staging." International Journal of Gynecologic Cancer 14, no. 2 (2004): 259–70. http://dx.doi.org/10.1136/ijgc-00009577-200403000-00012.

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Epithelial ovarian carcinoma rarely occurs because of a single event. Therefore, no single biological tumor factor will give accurate prognostic information for all ovarian cancer patients. On the other hand, a combination of two or more independent factors may yield an improved overall prognostic index. Because FIGO stage is included in most of the previously presented models, inaccurate surgical staging in patients with apparently early disease has been a problem. In a series of 226 patients with epithelial ovarian carcinomas in FIGO stages IA–IIC, a number of clinicopathological factors (ag

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Hilpert, Krause, Venhoff, Kühnle, Schem, and Maass. "Das epitheliale Ovarialkarzinom." Therapeutische Umschau 64, no. 7 (2007): 375–80. http://dx.doi.org/10.1024/0040-5930.64.7.375.

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Das epitheliale Ovarialkarzinom (OC) ist das gynäkologische Malignom mit der höchsten krebsbedingten Mortalität, da 2/3 der Patientinnen in einem fortgeschrittenen Stadium diagnostiziert werden. Ursächlich ist hierfür die unspezifische Symptomatik und das Fehlen suffizienter Früherkennungsmethoden. Bislang existieren vorwiegend klinische und histopathologische Prognosefaktoren, von denen das FIGO-Stadium und der postoperativ verbliebene Tumorrest überragende Bedeutung haben. Frühe Stadien des OC (FIGO Ia-IIa) haben eine gute Prognose mit Überlebensraten von etwa 90%, die komplette Tumorresekti

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Smart, Alicia, Daniela Buscariollo, Gabriela Alban, et al. "Low-dose adjuvant vaginal cylinder brachytherapy for early-stage non-endometrioid endometrial cancer: recurrence risk and survival outcomes." International Journal of Gynecologic Cancer 30, no. 12 (2020): 1908–14. http://dx.doi.org/10.1136/ijgc-2020-001623.

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ObjectiveThe aim of this study was to evaluate recurrence patterns and survival outcomes for patients with early-stage non-endometrioid endometrial adenocarcinoma treated with adjuvant high-dose rate vaginal brachytherapy with a low-dose scheme.MethodsA retrospective review was performed of patients with International Federation of Gynecology and Obstetrics (FIGO) stage I–II non-endometrioid endometrial cancer who received adjuvant vaginal brachytherapy with a low-dose regimen of 24 Gy in six fractions from November 2005 to May 2017. All patients had >6 months of follow-up. Rates of recurre

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Romeo, Clémence, Olivia Le Saux, Margaux Jacobs, et al. "Therapeutic Challenges in Patients with Gynecologic Carcinosarcomas: Analysis of a Multicenter National Cohort Study from the French Prospective TMRG Network." Cancers 14, no. 2 (2022): 354. http://dx.doi.org/10.3390/cancers14020354.

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Background: Gynecological carcinosarcomas are rare and aggressive diseases, with a poor prognosis. The rarity of these tumors explains the lack of robust and specific data available in the literature. The objective of this study was to investigate the impact of initial adjuvant treatment and recurrent therapeutic strategies. Patients and methods: A multicentric cohort study within the French national prospective Rare Malignant Gynecological Tumors (TMRG) network was conducted. Data from all included carcinosarcomas diagnosed between 2011 and 2018 were retrospectively collected. Results: 425 ca

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Lo, K. W. K., T. H. Cheung, M. Y. Yu, S. F. Yim, and T. K. H. Chung. "The value of pelvic and para-aortic lymphadenectomy in endometrial cancer to avoid unnecessary radiotherapy." International Journal of Gynecologic Cancer 13, no. 6 (2003): 863–69. http://dx.doi.org/10.1136/ijgc-00009577-200311000-00019.

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The case histories of 95 patients with endometrial carcinoma treated between July 1998 and December 2002 were reviewed. These patients were staged according to FIGO classification and included peritoneal cytology, total abdominal hysterectomy/bilateral salpingo-oophorectomy (TAHBSO), and pelvic with or without para-aortic lymphadenectomy. The FIGO surgical stages were as follow: IA, 9 (9.5%); IB, 35 (36.8%); IC, 16 (16.8%); IIB, 10 (10.5%); IIIA, 5 (5.3%); IIIB, 1 (1.1%); IIIC, 19 (20.0%). In addition to TAHBSO, 47 (49.5%) patients had pelvic lymphadenectomy whereas 48 (50.5%) had both pelvic

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