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1

Witzel, Thomas Ph D. Massachusetts Institute of Technology. "Methods for functional brain imaging." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/68459.

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Анотація:
Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Magnetic resonance imaging (MRI) has demonstrated the potential for non-invasive mapping of structure and function (fMRI) in the human brain. In this thesis, we propose a series of methodological developments towards improved fMRI of auditory processes. First, the inefficiency of standard fMRI that acquires brain volumes one slice at a time is addressed. The proposed single-shot method is capable, for the first time, of imaging the e
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2

Au, Pakwai. "Engineering functional blood vessels in vivo." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43867.

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Анотація:
Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2008.<br>Includes bibliographical references.<br>At the present time, there are many hurdles to overcome in order to create a long-lasting and engineered tissue for tissue transplant in patients. The challenges include the isolation and expansion of appropriate cells, the arrangement of assorted cells into correct spatial organization, and the development of proper growth conditions. Furthermore, the creation of a three dimensional engineered tissue is limited by the fact that tissue assemblies greater than 100-200 microm
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3

Yoo, Seung-Schik 1970. "Adaptive functional magnetic resonance imaging." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/70893.

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Анотація:
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 2000.<br>Some research performed with the Harvard-M.I.T. Division of Health Sciences and Technology.<br>Includes bibliographical references (leaves 132-140).<br>Functional MRI (fMRI) detects the signal associated with neuronal activation, and has been widely used to map brain functions. Locations of neuronal activation are localized and distributed throughout the brain, however, conventional encoding methods based on k-space acquisition have limited spatial selectivity. To improve it, we propose an adaptive fM
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4

Doshi, Vishal D. (Vishal Devendra). "Functional compression : theory and application." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43038.

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Анотація:
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science; and, (S.M. in Technology and Policy)--Massachusetts Institute of Technology Engineering Systems Division, Technology and Policy Program, 2008.<br>Includes bibliographical references (p. 75-77).<br>We consider the problem of functional compression. The objective is to separately compress possibly correlated discrete sources such that an arbitrary deterministic function of those sources can be computed given the compressed data from each source. This is motivated by problems in sensor netw
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5

Demir, Özlem. "Functional Characterization of Microtubule Associated Proteins in ES Cell Division and Neuronal Differentiation." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-163103.

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Microtubules are tubular polymers that are involved in a variety of cellular processes such as cell movement, mitosis and intracellular transport. The dynamic behavior of microtubules makes this possible because all of these processes require quick responses. Embryonic stem (ES) cells were first isolated from mouse embryos and they have two unique characteristics; they can be kept undifferentiated for many passages with a stable karyotype and they can be differentiated into any type of cells under appropriate conditions. The pluripotency of ES cells, their ease of manipulation in culture, and
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6

McMullen, Samuel. "Injury Prediction in Division-I Collegiate Cross-Country Runners using Functional Movement Tests." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1369821797.

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7

Athanassiou-Papaefthymiou, Maria G. "Functional activation of the p53 tumor suppressor in non-tumorigenic variants of the HeLa cervical carcinoma cell line." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/39376.

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8

Maas, Luis C. (Luis Carlos). "Processing strategies for functional magnetic resonance imaging data sets." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/85262.

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Анотація:
Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 1999.<br>Includes bibliographical references (leaves 108-118).<br>by Luis Carlos Maas, III.<br>Ph.D.
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9

Ford, Adam J. "Functional Movement Screening as a Predictor of Injury in Division One Collegiate Football Athletes." University of Toledo / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1300728080.

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10

Abedin, Asma. "Structural and Functional Analysis of the Cell Division Protein MinDNg: Implications of the C-terminus." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20029.

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Анотація:
Gram-negative bacteria such as Escherichia coli and Neisseria gonorrhea undergo symmetric cell division controlled in part by the Min system constituting of MinC, MinD and MinE. MinDNg is a peripheral membrane ATPase that functions by recruiting cell division inhibitor MinCNg to the membrane where it prevents septation. The available crystallographic data of archeal monomeric MinD is not ideal for a dimeric bacterial MinD homolog since there is only 30-40% sequence identity between the two organisms. In addition, the C-terminus of monomeric MinD is disordered in the crystal structures, which l
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11

Zhao, Ruilin 1972. "Functional analysis of middle temporal visual area and its associated behavior." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/8084.

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Анотація:
Thesis (Ph. D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 2002.<br>Includes bibliographical references (leaves 106-120).<br>Our lab's long-term goal is to elucidate the circuitry of the visual cortex, to develop quantitative computational models of neuronal function in the visual cortex, and to establish how these models may relate to visual perception and visually guided behavior. Central to this goal is the analysis of functional architecture, which is crucial to an understanding of how the brain works. In my thesis research, I applied behavi
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12

Fernández, Cecilia A. 1969. "Functional and structural uncoupling of the angiogenic and enzymatic inhibitory activity of TIMPs : loop 6 of TIMP-2 is a novel inhibitor of angiogenesis." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/31110.

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Thesis (Ph. D. in Applied Biosciences)--Massachusetts Institute of Technology, Biological Engineering Division, 2004.<br>Includes bibliographical references (leaves 119-130).<br>Tissue inhibitors of metalloproteinases (TIMPs) regulate tumor growth, progression and angiogenesis in a variety of experimental cancer models and in human malignancies. However, numerous studies have revealed important differences between TIMP family members in their ability to inhibit angiogenic processes in vitro and angiogenesis in vivo despite their universal ability to inhibit matrix metalloproteinase (MMP) activ
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13

Talavage, Thomas Michael 1971. "Functional magnetic resonance imaging of the frequency organization of human auditory cortex." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/49662.

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Анотація:
Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 1998.<br>Includes bibliographical references (leaves 134-143).<br>by Thomas Michael Talavage.<br>Ph.D.
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14

Purdon, Patrick L. (Patrick Lee) 1974. "Multimodal neuroimaging with simultaneous electroencephalogram and high-field functional magnetic resonance imaging." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/33074.

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Анотація:
Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2005.<br>Includes bibliographical references.<br>Simultaneous recording of electroencephalogram (EEG) and functional magnetic resonance imaging (tMRI) is an important emerging tool in functional neuroimaging with the potential to reveal new mechanisms for brain function by combining the high spatial resolution of fMRI with the high temporal resolution of EEG. Applications for this technique include studies of sleep, epilepsy, and anesthesia, as well as basic sensory, perceptual, and cognitive processes. Unlike methods tha
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15

Ghaffari, Roozbeh 1979. "The functional role of the mammalian tectorial membrane in the cochlear mechanics." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43876.

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Анотація:
Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2008.<br>Includes bibliographical references (p. 101-110).<br>Sound-evoked vibrations transmitted into the mammalian cochlea produce traveling waves that provide the mechanical tuning necessary for spectral decomposition of sound. These traveling waves of motion propagate along the basilar membrane (BM) and ultimately stimulate the mechano-sensory receptors. The tectorial membrane (TM) plays a key role in this stimulation process, but its mechanical function remains unclear. Here we show that the TM supports traveling wav
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16

Brown, Matthew. "The Ability of the Functional Movement Screen in Predicting Injury Rates in Division I Female Athletes." University of Toledo / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1302275741.

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17

Buran, Bradley N. (Bradley Nicholas). "Precision and reliability of cochlear nerve response in mice lacking functional synaptic ribbons." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/54454.

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Анотація:
Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2009.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 87-99).<br>Synaptic ribbons are electron-dense structures surrounded by vesicles and anchored to the presynaptic membrane of photoreceptors, retinal bipolar cells and hair cells. Ribbon synapses are characterized by sustained exocytosis that is graded with stimulus intensity and can achieve high release rates. Leading hypotheses implicate the ribbon in maintenance of a large readily releasable pool (RRP) of presynaptic vesicles which
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18

Sigalovsky, Irina S. 1972. "Structural and functional distinctions between auditory centers revealed with MRI in living humans." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/30272.

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Анотація:
Thesis (Ph. D.)--Harvard University--MIT Division of Health Sciences and Technology, 2005.<br>Vita.<br>Includes bibliographical references.<br>From brainstem to cortex, sound is processed in centers that are functionally and structurally distinct. In animals, invasive electrophysiology and histology has revealed these distinctions and, consequently, organizational principles behind sound processing. In humans, however, comparable demonstrations are sparse. This thesis presents three MRI studies that provide new information regarding structural and functional distinctions between auditory cente
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19

Aguirre, Aaron Dominic 1977. "Advances in Optical Coherence Tomography and Microscopy for endoscopic applications and functional neuroimaging." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43740.

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Анотація:
Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2008.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Includes bibliographical references.<br>Optical Coherence Tomography (OCT) is a developing medical imaging technology that generates micron resolution cross-sectional images of subsurface internal tissue structure in situ and in real time, without the need to remove and process specimens. Previous studies have suggested that OCT holds great potential for use in lapa
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20

Xie, Zidian. "FUNCTIONAL CHARACTERIZATION OF FLP, A MYB TRANSCRIPTION FACTOR INVOLVED IN ARABIDOPSIS STOMATAL DEVELOPMENT." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1250085562.

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21

Ekstrom, Leeland Bruce. "Combined fMRI and electrical microstimulation to determine functional connections in visual areas of the primate brain." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/47848.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2009.<br>Includes bibliographical references (p. 69-83).<br>The use of functional magnetic resonance imaging (fMRI) to study the non-human primate brain has been developed over the past decade. Primate fMRI has many attractive features: it allows validation of previous homology assumptions between humans and monkeys, provides a model to combine imaging with invasive techniques to directly manipulate the brain, and can guide other modalities, such as electrophysiology, to new areas of interest. The frontal eye field (FEF)
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22

Lauster, Theresa [Verfasser]. "Functional characterization of Arabidopsis thaliana ROP GTPase activating proteins during cell division and pavement cell morphogenesis / Theresa Lauster." Tübingen : Universitätsbibliothek Tübingen, 2023. http://d-nb.info/1237684471/34.

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23

Kim, Haein. "Temporal Coordination Of Mitotic Chromosome Alignment And Segregation: Structural And Functional Studies Of Kif18a." ScholarWorks @ UVM, 2018. https://scholarworks.uvm.edu/graddis/930.

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Анотація:
Chromosome alignment is highly conserved in all eukaryotic cell divisions. Microtubule (MT) -based forces generated by the mitotic spindle are integral for proper chromosome alignment and equal chromosome segregation. The kinetochore is a multi-subunit protein complex that assembles on centromeric regions of chromosomes. Kinetochores tether chromosomes to MTs (K fibers) that emanate from opposite poles, in a process called biorientation. This linkage translates K fiber dynamics into chromosome movements during alignment and segregation. Stable, high-affinity kinetochore attachments promote spi
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24

Acharya, Sudeep. "Biochemical, structural and functional analysis of the cell division site determinant MinD(Ng): To divide or not to divide." Thesis, University of Ottawa (Canada), 2006. http://hdl.handle.net/10393/27216.

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Анотація:
The Min system, constituting MinC, MinD, and MinE proteins plays an essential role in regulating cell division in Gram-negative bacteria. MinD, a peripheral membrane ATPase, functions by recruiting the cell division inhibitor, MinC, to the membrane where it prevents septation. Counteracting this effect is MinE which can bind to MinD, thereby displacing MinC. Formation of the MinE-MinD complex also stimulates the ATPase activity of MinD, and is required for the periodic oscillations of the MinC-MinD complex on and off the membrane required for normal cell division. Our laboratory has shown that
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25

Buchner, Kristina [Verfasser], and Esther [Akademischer Betreuer] Zanin. "Functional characterization of the BRCT domains of the RhoA GEF Ect2 during cell division / Kristina Buchner ; Betreuer: Esther Zanin." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1234911396/34.

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26

Yu, Yu. "Functional characterization of the cyclin, Nicta, CYCA3; 2, and the SET domain proteins in plants." Université Louis Pasteur (Strasbourg) (1971-2008), 2006. https://publication-theses.unistra.fr/public/theses_doctorat/2006/YU_Yu_2006.pdf.

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Анотація:
Contrairement à celui des animaux, le développement des plantes est pour une grande part post-embryonnaire et beaucoup plus influencé par l'environnement. Ceci suggère que les plantes ont évolué en élaborant différents mécanismes pour contrôler leur développement et leur croissance. La division cellulaire joue un rôle essentiel dans le développement et la croissance de la plante. Durant cette division, la transition G1-S est une étape décisive vers la prolifération cellulaire ou la différenciation. Par des approches génétiques, physiologiques et moléculaires, nous avons montré que Nicta;CYCA3;
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27

Morrell, Matt D. "Lower Extremity Injury Predictability of the Functional Movement Screen and the Star Excursion Balance Test Among Division I College Football Players." University of Toledo / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1333546254.

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28

Brioudes, Florian. "Regulation of organ morphogenesis : Functional analysis of the TRANSLATIONALLY CONTROLLED TUMOR PROTEIN and of the transcription factor BIGPETALp in Arabidopsis thaliana." Lyon, Ecole normale supérieure, 2010. http://www.theses.fr/2010ENSL0602.

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Dans les organismes pluricellulaires la morphogenèse nécessite une étroite régulation de la prolifération, de la croissance et de la mort cellulaire, permettant la formation d’organes aux formes et tailles bien spécifiques. Au cours de ma thèse, je me suis intéressé aux rôles biologiques de deux gènes impliqués dans la morphogenèse des organes chez Arabidopsis thaliana, TRANSLATIONALLY CONTROLLED TUMOR PROTEIN (AtTCTP) et BIGPETALp (BPEp). J’ai montré que AtTCTP est essentiel pour le développement des plantes et que AtTCTP contrôle la progression du cycle cellulaire, au niveau de la transition
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29

Tucker, Corey L. (Corey Logan). "Can we reduce parking at MIT : design and development of a functional commuter dashboard." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104824.

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Анотація:
Thesis: S.M. in Technology and Policy, Massachusetts Institute of Technology, School of Engineering, Institute for Data, Systems, and Society, Technology and Policy Program, 2016.<br>Thesis: S.M. in Transportation, Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 98-102).<br>This thesis presents the design, development and initial implementation of a new commuter dashboard tool entitled AccessMyCommute for use by all MIT employees. This is the first in a series
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30

Greco, Valerie S. "Functional analysis of the role of conserved glycine residues and N-terminus motifs in the cell division inhibitor MinC from Neisseria gonorrhoeae." Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/26647.

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MinC is the principle inhibitor of cell division in the Gram negative coccus Neisseria gonorrhoeae. Multiple alignment of 28 minC homologues from prokaryotic organisms revealed the conservation of four glycines in the C-terminus. Radical mutations of these residues, G138D, G157D, G164S, and G174E, were introduced to minCNg using site-directed mutagenesis and were expressed heterologously in Escherichia coli. Microscopic analysis of cellular morphology revealed abrogation of MinCNg function as indicated by the inability of the overexpressed protein to induce filamentation, and flow cytometry s
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31

Seth, Alpna. "Functional Analysis of the c-MYC Transactivation Domain: A Dissertation." eScholarship@UMMS, 1992. https://escholarship.umassmed.edu/gsbs_diss/315.

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Many polypeptide growth factors act by binding to cell surface receptors that have intrinsic tyrosine kinase activity. Binding of these growth factors to their cognate receptors results in the initiation of mitogenic signals which then get transduced to the interior of the cell. A critical target for extracellular signals is the nucleus. A plethora of recent evidence indicates that extracellular signals can affect nuclear gene expression by modulating transcription factor activity. In this study, I have determined that the transactivation domain of c-Myc (protein product of the c-myc proto-onc
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32

Fonçatti, Camilla Fiedler. "Long-term stability of Class II division 1 treatment with the MARA combined with fixed appliances." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/25/25144/tde-19072018-105455/.

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Introduction: Successful treatment of class II Division 1 malocclusion is also implied to the long-term stability of treatment changes and many are the factors that can influence that. Objective: This research aimed to evaluate the long-term stability of the cephalometric changes obtained during Class II malocclusion correction with the MARA (Mandibular Anterior Repositioning Appliance) associated with fixed appliances. Methods: The treatment group comprised 12 patients who were evaluated at three stages: pretreatment (T1), posttreatment (T2) and long-term posttreatment (T3). The mean initial
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33

Demir, Özlem [Verfasser], Jonathon [Akademischer Betreuer] Howard, and Francis [Akademischer Betreuer] Stewart. "Functional Characterization of Microtubule Associated Proteins in ES Cell Division and Neuronal Differentiation / Özlem Demir. Gutachter: Jonathon Howard ; Francis Stewart. Betreuer: Jonathon Howard." Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://d-nb.info/1069096644/34.

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34

Garcia, Pierre. "Prédiction de liens fonctionnels par détection de coévolution entre familles de gènes : application aux gènes du cycle cellulaire chez les Firmicutes." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSE1316/document.

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Анотація:
Le cycle cellulaire chez les bactéries est un processus très étudié mais il apparait que les modèles actuels ne rendent pas compte de la complexité et surtout de la diversité des machineries et des mécanismes de régulation impliqués. En fait, notre connaissance du cycle cellulaire repose sur l'étude de quelques organismes modèles. Or les analyses comparatives ont montré que certains systèmes et mécanismes décrits sont peu conservés et donc difficilement transposables d'un taxon à l'autre. Des approches évolutives telles que la phylogénomique peuvent être utilisées pour l'étude fonctionnelle de
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35

Hedley, Paula Louise. "Molecular and functional characterisation of Long QT Syndrome causing genes." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86480.

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Анотація:
Thesis (PhD)-- Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: Ventricular arrhythmias are the most important cause of sudden cardiac death (SCD) among adults living in industrialised nations. Genetic factors have substantial effects in determining population-based risk for SCD and may also account for inter-individual variability in susceptibility. Great progress has been made in identifying genes underlying various Mendelian disorders associated with inherited arrhythmia susceptibility. The most well studied familial arrhythmia syndrome is the congenital long QT syndrome (LQTS) caused by
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36

Rabia, Tarek. "Virtualisation des fonctions d'un Cloud Radio Access Network(C-RAN)." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS009/document.

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Анотація:
La nouvelle génération de réseaux mobiles (5G) devrait faire face, durant les cinq prochaines années, à une importante croissance du volume de données, échangé entre plusieurs milliards d'objets et d'applications connectés. En outre, l'émergence de nouvelles technologies, telles que Internet of Things (IoT), conduite autonome et réalité augmentée, impose de plus fortes contraintes de performance et de qualité de service (QoS). Répondre aux besoins cités, tout en réduisant les dépenses d'investissement et d'exploitation (CAPEX/OPEX), sont les objectifs poursuivis par les opérateurs télécom, qui
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37

Austin, Denise Lynmarie. "Bringing Functional Family Probation Services to the Community: A Qualitative Case Study." PDXScholar, 2013. https://pdxscholar.library.pdx.edu/open_access_etds/1436.

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In March 2011, Multnomah County's Juvenile Services Division (JSD) in Portland, Oregon implemented a new program model called Functional Family Probation Services, a case management model based on the principles of Functional Family Therapy. Under this model JSD Juvenile Court Counselors deliver Functional Family Probation Services to medium and high-risk youth on probation; both to the youth and their family in their home. This qualitative case study examined the extent to which the Juvenile Court Counselors and Community Justice Managers implemented Functional Family Probation Service's comp
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38

Rabia, Tarek. "Virtualisation des fonctions d'un Cloud Radio Access Network(C-RAN)." Electronic Thesis or Diss., Sorbonne université, 2018. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2018SORUS009.pdf.

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La nouvelle génération de réseaux mobiles (5G) devrait faire face, durant les cinq prochaines années, à une importante croissance du volume de données, échangé entre plusieurs milliards d'objets et d'applications connectés. En outre, l'émergence de nouvelles technologies, telles que Internet of Things (IoT), conduite autonome et réalité augmentée, impose de plus fortes contraintes de performance et de qualité de service (QoS). Répondre aux besoins cités, tout en réduisant les dépenses d'investissement et d'exploitation (CAPEX/OPEX), sont les objectifs poursuivis par les opérateurs télécom, qui
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39

Pedroza-Garcia, José Antonio. "Functional characterization of the DNA Polymerase epsilon and its involvement in the maintenance of genome integrity in Arabidopsis." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS248.

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Contrairement aux animaux, les plantes ont un développement largement post-embryonnaire et forment continuellement de nouveaux organes et tissus grâce à l’activité de leurs méristèmes. Ces massifs de cellules indifférenciées conservent la capacité à se diviser tout au long de la vie de la plante, et c’est également à partir du méristème caulinaire que se forment les gamètes. Chaque cycle de division peut être la source de mutations, suite par exemple à des erreurs de réplication. De plus, les méristèmes sont relativement exposés aux stress environnementaux qui peuvent également endommager l’AD
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40

Carvalhal, Sara. "Characterisation of ALADIN's function during cell division." Thesis, University of Dundee, 2015. https://discovery.dundee.ac.uk/en/studentTheses/cb6fe2ac-a17b-487e-ae16-a646e6576534.

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Cell division relies on many steps, precisely synchronised, to ensure the fidelity of chromosome segregation. To achieve such complex and multiple functions, cells have evolved mechanisms by which one protein can participate in numerous events on the cell life. Over the past few years, an increasing number of functions have been assigned to the proteins of the nuclear pore complex (NPC) also called nucleoporins. NPCs are large complexes studded in the nuclear envelope, which control the nucleocytoplasmic transport. It is now known that nucleoporins participate in spindle assembly, kinetochore
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Plüß, Marlene [Verfasser], and Bernhard [Akademischer Betreuer] Brenner. "Cellular phenotyping of human heart disease$dstructural and functional changes in dilated cardiomyopathy / Marlene Plüß. Institut für Molekular- und Zellphysiologie der Medizinischen Hochschule Hannover. Randall Division of Cell and Molecular Biophysics am King's College London, United Kingdom. Betreuer: Bernhard Brenner." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2015. http://d-nb.info/1088319270/34.

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42

Berry, David (David A. ). "Glycosaminoglycan regulation of cell function." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/34153.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Biological Engineering Division, 2005.<br>Includes bibliographical references (p. 252-285).<br>Glycosaminoglycans (GAGs) are complex polysaccharides that exist both on the cell surface and free within the extracellular matrix. The intrinsic sequence variety stemming from the large number of building blocks that compose this biopolymer leads to substantial information density as well as to the ability to regulate a wide variety of important biological processes. With the recent and progressive emergence of biochemical and analytical tools
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43

Blomkvist, Niklas. "Moments of divisor sum functions." Thesis, Uppsala University, Department of Mathematics, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-120983.

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44

Grant, David R. MD FRCSC. "Theta functions and division points on Abelian varieties of dimension two." Thesis, Massachusetts Institute of Technology, 1985. http://hdl.handle.net/1721.1/115469.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mathematics, 1985.<br>MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.<br>Bibliography: leaves 123-124.<br>by David R. Grant.<br>Ph.D.
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45

Noh, Minsoo. "Self-renewal pattern-associated genes and their role in adult stem cell functions." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/37955.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Biological Engineering Division, 2006.<br>"June 2006."<br>Includes bibliographical references (leaves 175-187).<br>Molecular markers for adult stem cells (ASCs) are highly demanded for research and clinical applications. The development of specific molecular markers for ASCs has been difficult mainly due to the technical barriers in the identification and isolation of rare ASCs. Previously, reported transcriptional profiling studies for defining molecular features of ASCs were compromised by the use of impure ASC preparations. Thesis for
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46

Saikia, Anupam. "Iwasawa theory of Lubin-Tate division towers and ρ-Adic L-functions". Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620239.

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47

Morelli, E. "NOVEL FUNCTIONS OF THE SNARE PROTEIN SNAP29IN MEMBRANE TRAFFICKING AND CELL DIVISION." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/265475.

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Vesicular trafficking within cells is an important process for tissue development and homeostasis. A key step of vesicular trafficking is the fusion between two membranes, a process in which SNARE (Soluble NSF Attachment Protein Receptors) proteins play a fundamental role. SNAP29 (SyNaptosomal Associated Proteins 29) is a ubiquitous SNARE, regulating membrane fusion in different trafficking compartments and in different contexts in non dividing cells. We isolated a loss of function mutant in usnp, the gene encoding the Drosophila homolog of the human protein SNAP29 (Snap29 hereafter), that, wh
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48

Woodward, Claire J. D. A. "Identifying genes that mediate shoot meristemless function during meristem development in Arabidopsis thaliana." Thesis, University of East Anglia, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268550.

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49

Fike, Randy L. (Randy Lynn). "Supply chain risk management : (redefining the audit function within a large industrial company)." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/33316.

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Thesis (M. Eng. in Logistics)--Massachusetts Institute of Technology, Engineering Systems Division, 2005.<br>Includes bibliographical references (leaves 72-74).<br>As supply chains become more sophisticated, difficulties with their operation can become more complex as well. An organization must ensure the flow of goods and services end- to-end across the supply chain at the promised level and at the anticipated cost. This thesis describes the redesign and centralization of the supply chain operating model of a large industrial company, and suggests a structure capable of mitigating supply chai
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Elihu, David Morad. "Regulation of specific connexins differentially alters gap junction permeability and endothelial cell function." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/37974.

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Thesis (M. Eng.)--Massachusetts Institute of Technology, Biological Engineering Division, 2006.<br>Includes bibliographical references (leaves 80-84).<br>While many have explored how vascular processes alter gap junction communication and composition few have analyzed the role of specific gap junction connexin proteins in regulating cellular communication and wound healing. Using RNA interference or peptide inhibitors to downregulate specific connexins we examined the role of gap junctions in intercellular diffusion, calcium excitation, and in mediating the expression of vascular regulators tr
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