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Дисертації з теми "Fungal diagnostic"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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1

Zeng, Qing-Yin. "Development of molecular techniques for fungal diagnostic research." Doctoral thesis, Umeå : Umeå universitet : Arbetslivsinstitutet, 2005. http://kb.se/resolve?urn=urn:nbn:se:umu:diva-656.

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2

Shankland, Gillian Sheana. "Diagnostic, epidemiological and pathological aspects of opportunistic mycoses." Thesis, University of Glasgow, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293455.

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3

Ntuli, Sindile Venessa. "Validation of a Pan-fungal polymerase chain reaction (PCR) assay for the detection and identification of medically important fungi in a diagnostic laboratory." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/27816.

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The laboratory diagnosis of fungal infection is complicated, based on the microscopic detection, culture isolation, and detection of serological response. In recent years, there has been an increase in the utilization of molecular diagnostic techniques for the detection and accurate identification of fungal pathogens. This was a laboratory accuracy study evaluating the performance of a selected pan-fungal PCR using 70 previously identified reference fungal isolates. The DNA yield and purity of three different DNA extraction methods was assessed, using 6 representative fungal isolates. The ZR F

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4

Mohr, Alexandra. "Use of a monoclonal antibody to detect gray mold (Botrytis cinerea) in strawberry." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33812.

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Gray mold, caused by Botrytis cinerea is the major cause of postharvest loss in strawberries. Detection of flower and fruit infections enables producers to make intelligent management decisions. A plate-trapped ELISA protocol using a Botrytis-specific monoclonal antibody (BC-12.CA4) was developed for the detection of Botrytis cinerea in strawberry flower receptacles and red fruits. Horseradish peroxidase, was chosen as enzyme conjugate because it gave lower background absorbance in disease-free samples. B. cinerea reference antigen (RAg) was isolated from strawberry. BC-12.CA4 was very sensiti

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5

Incamps, Anne. "Développement d'une stratégie de quantification multiplexée par spectrométrie de masse pour la recherche de nouveaux biomarqueurs protéiques dans le diagnostic du sepsis fongique." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTT060.

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Les avancées en protéomique de ces dernières décennies ont permis l’identification de nombreux biomarqueurs prometteurs pour le diagnostic, pronostic ou suivi thérapeutique de pathologies particulières. Cependant, peu de nouvelles protéines sont libérées sur le marché, faute d’une identification pertinente et une validation clinique efficace. Le développement d’une approche ciblée, dès l’identification des cibles potentielles, associé à une stratégie de quantification robuste permet d’assurer une fiabilité dans les étapes d’identification, de vérification et de validation clinique. Cette appro

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6

Gorton, Rebecca Louise. "Molecular diagnosis of invasive fungal disease." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10047377/.

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BACKGROUND: Invasive fungal infections (IFI) are opportunistic infections caused by yeast or filamentous fungi, typically presenting in immunocompromised patients (haemato-oncology, intensive care, HIV, solid organ transplant settings). This research aims to comprehensively evaluate molecular diagnostics to address the current shortfall in IFI diagnosis and, where appropriate, embed molecular methods into routine clinical service. METHODS: Molecular methodologies, including PCR, MALDI-TOF MS and PNA-FISH, were evaluated on clinical sample cohorts from the Royal Free Hospital NHS Foundation Tru

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7

Green, Brett James. "Detection and diagnosis of fungal allergic sensitisation." University of Sydney, 2005. http://hdl.handle.net/2123/978.

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Doctor of Philosophy(PhD),<br>Airborne fungi are ubiquitous in the environment and human exposure is inevitable. Such fungi differ greatly in their taxonomic, physical, ecological and pathogenic characteristics. Currently, 69 000 species have been taxonomically classified and more than 80 of these are recognised to be aeroallergen sources. Many strategies have evolved to sample, identify and interpret fungal exposure to these species, however no strategy serves all purposes as exposure is a complex and dynamic process confounded by spatial, temporal and geographic variations in airborne counts

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8

Perez, Sierra Ana. "Systematics, diagnostics and epidemiology of the fungal genus Armillaria." Thesis, Birkbeck (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406210.

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Species in the genus Armillaria (Fr.:Fr.) Staude are major root pathogens of woody plants. A PCR-based technique was investigated aiming to develop a rapid and accurate method for identification of Armillaria species. Armillaria taxonomy has been extensively studied in Europe, North America and Australia. However, in Africa their taxonomy remains uncertain. A. mellea and A. heimii are the main species described. Morphological characteristics, somatic incompatibility, production of basidiomata in vitro, amplified fragment length polymorphisms (AFLPs), DNA profiles generated by polymerase chain

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9

Chryssanthou, Erja. "Studies on laboratory diagnosis of fungal infection and antifungal susceptibility /." Stockholm, 1998. http://diss.kib.ki.se/search/diss.se.cfm?19981016chry.

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10

Hughes, Kelvin J. D. "Molecular methods for the diagnosis of fungal quarantine plant pathogens." Thesis, University of Bristol, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272031.

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11

Olsson, Mats. "Detection and identification of Pneumocystis carinii-DNA : emphasis on laboratory diagnosis and occurrence in air /." Stockholm, 1998. http://www.kib.ki.se/ki/diss/980403olss.html.

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12

Al-Maqtoofi, Marwan Yaseen Abdulmajeed. "Investigating host and environmental influences of Fusarium solani using a novel monoclonal antibody." Thesis, University of Exeter, 2016. http://hdl.handle.net/10871/23409.

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Human fungal infections among severely immunocompromised individuals have increased dramatically over the last 30 years and that coincidence with an expanding patient numbers of bone marrow and solid organ transplantation and those receiving aggressive cytotoxic chemotherapy for neoplastic diseases or immunosuppressive drugs. In recent years, many of opportunistic fungi have emerged as serious human pathogens and causing life-threatening infections of humans such as Fusarium species. Due to lack of a highly accurate diagnostic test for tracking the pathogenic Fusarium species, fusariosis is fr

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13

Gomez, Giraldo Beatriz Lucia. "Development of novel antigen detection tests for the diagnosis and follow up of patients with histoplasmosis and paracoccidioidomycosis using monoclonal antibodies." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340490.

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14

McLintock, Lorna. "Genetic predisposition to, prevention and early diagnosis of invasive fungal infection in haemato-oncology patients." Thesis, University of Glasgow, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433620.

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15

McMullan, R. "The diagnosis of invasive fungal infection in critically-ill patients using real-time PCR technology." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446125.

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16

Hafez, Khafaga Ahmed Ibrahem 1987. "Bioinformatics approaches for integration and analysis of fungal omics data oriented to knowledge discovery and diagnosis." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2021. http://hdl.handle.net/10803/671160.

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Aquesta tesi presenta una sèrie de recursos bioinformàtics desenvolupats per a donar suport en l'anàlisi de dades de NGS i altres òmics en el camp d'estudi i diagnòstic d'infeccions fúngiques. Hem dissenyat tècniques de computació per identificar nous biomarcadors i determinar potencial trets de resistència, pronosticant les característiques de les seqüències d'ADN/ARN, i planejant estratègies optimitzades de seqüenciació per als estudis de hoste-patogen transcriptomes (Dual RNA-seq). Hem dissenyat i desenvolupat tambe una solució bioinformàtica composta per un component de costat de servidor

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17

Lardner, Richard. "Early diagnosis and detection of Eutypa dieback of grapevines." Title page, table of contents and abstract only, 2003. http://hdl.handle.net/2440/37969.

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Eutypa dieback of grapevines, caused by Eutypa lata, is a major cause of reduced longevity in vineyards worldwide. The fungus grows in the woody tissue of infected vines, producing translocatable toxins that cause foliar symptoms of the disease. By the time foliar symptoms are evident the pathogen may have become well established in the vine. One aim of this study was to develop DNA markers to allow rapid reliable identification of E. lata and to detect the pathogen in infected wood. The second aim was to analyse secondary metabolite production by E. lata in order to gain information on the co

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18

Olsson, Christer H. B. "Diagnosis of root-infecting Phytophthora spp. /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5483-2.pdf.

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19

Silva, Elaine Gagete Miranda da. "Fungos anemófilos na cidade de Botucatu e sua correlação com sensibilização em portadores de doenças alérgicas respiratórias." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5146/tde-09102014-103202/.

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Introdução: Fungos são alérgenos cuja importância nas doenças alérgicas respiratórias é subestimada por falta de extratos alergênicos adequados para diagnóstico, quer através de testes cutâneos, quer através de dosagem de IgE específica. Botucatu possui características próprias por se localizar numa \"cuesta\" e possuir vegetação variada que cobre grande parte da cidade. A partir das plantas os fungos ganham o ar através da esporulação podendo ser inalados e sensibilizar pacientes com alergias respiratórias. Este trabalho se propõe a estudar quais os fungos mais prevalentes em Botucatu e a tax

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20

Rebeis, Eduardo Baldassari. "Índice antropométrico para "pectus excavatum" como método diagnóstico e de avaliação pré e pós-operatória: análise comparativa com o índice de Haller e o índice vertebral inferior." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5156/tde-17082005-123221/.

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Estamos propondo um índice antropométrico para pectus excavatum correlacionando-o ao índice de Haller e ao índice vertebral inferior. Estudamos 20 pacientes com deformidade e 30 indivíduos normais. Os pacientes portadores do defeito torácico foram submetidos à correção cirúrgica. A correlação entre os índices foi alta, a acurácia semelhante e houve diferença significante entre o pré e pós-operatório estabelecida pelos índices.<br>We are proposing an anthropometric index for pectus excavatum correlating it to Haller's index and to the lower vertebral index. We have studied 20 patients with defo

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21

Ramiro, Juliana. "Detecção molecular de fungos fitopatogênicos associados às sementes de soja." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/11/11135/tde-28042015-143631/.

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Fungos fitopatogênicos veiculados por sementes de soja podem causar sérios prejuízos à cultura, bem como danos diretos reduzindo o poder germinativo, vigor e emergência das sementes. A detecção e identificação precisa de fitopatógenos é uma das estratégias mais importantes para iniciar as medidas preventivas ou curativas no controle de doenças de plantas. Para se evitar a introdução e propagação de patógenos em áreas onde ainda não ocorrem, uma atenção especial deve ser tomada na detecção de agentes patogênicos em sementes. Os métodos tradicionalmente utilizados para detectar e identificar fun

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22

Gräser, Yvonne. "Molekulare Systematik und Evolution der Spezies der Familie Arthrodermataceae (Dermatophyten)." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2002. http://dx.doi.org/10.18452/13794.

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Dermatophyten sind keratinophile Pilze, d.h. sie besiedeln und infizieren die Haut und ihre Anhangsgebilde (Haare, Nägel) bei Mensch und Tier. Die derzeit häufigsten durch Dermatophyten hervorgerufenen Infektionen sind die Onychomykose, Tinea pedis, Tinea capitis und Tinea corporis. Da Antimykotika nicht bei alle Erregern von Dermatophytosen gleich wirksam sind, sollte im Vordergrund einer Behandlung zunächst die korrekte Erregerdifferenzierung stehen. Konventionell erfolgt diese Differenzierung über morphologische Merkmale wie Form und Farbe der auf dem Nährmedium gewachsenen Pilzkolonie, cha

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23

Doud, Melissa S. "A Multi-Faceted Diagnostic Approach to Lung Infections in Patients with Cystic Fibrosis." FIU Digital Commons, 2010. http://digitalcommons.fiu.edu/etd/166.

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One in 3,000 people in the US are born with cystic fibrosis (CF), a genetic disorder affecting the reproductive system, pancreas, and lungs. Lung disease caused by chronic bacterial and fungal infections is the leading cause of morbidity and mortality in CF. Identities of the microbes are traditionally determined by culturing followed by phenotypic and biochemical assays. It was first thought that the bacterial infections were caused by a select handful of bacteria such as S. aureus, H. influenzae, B. cenocepacia, and P. aeruginosa. With the advent of PCR and molecular techniques, the polymicr

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24

ALOI, Francesco. "Molecular methods for the diagnosis and characterization of phytopathogenic fungi of quarantine concern or causing emerging plant diseases." Doctoral thesis, Università degli Studi di Palermo, 2021. http://hdl.handle.net/10447/516008.

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In the context of molecular techniques applied to Plant Pathology, this Ph.D. thesis has pursued the following major objectives: i) to develop new diagnostic protocols for fungal pathogens; ii) to study the metabolic and physiological effects determined by new and emerging fungal pathogens; iii) to contribute to develop management strategies of diseases caused by quarantine and/or emerging fungi on plant species typical of the Mediterranean region. To fulfill these objectives, the following specific studies have been developed: • “Fusarium circinatum an emergent and quarantine pathogen of pi

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25

Lima, Alita Moura de. "Potencial de substâncias coloridas produzidas por fungos endofíticos amazônicos para o diagnóstico baciloscópico da tuberculose." Universidade Federal do Amazonas, 2013. http://tede.ufam.edu.br/handle/tede/3104.

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Made available in DSpace on 2015-04-20T12:31:37Z (GMT). No. of bitstreams: 1 Alita Moura de Lima.pdf: 2197035 bytes, checksum: 64774d32c0950f346e45e0226627e35a (MD5) Previous issue date: 2013-10-31<br>Fundação de Amparo à Pesquisa do Estado do Amazonas<br>Tuberculosis (TB), an infectious disease that occurs in 90% of cases in the lungs, is caused by Mycobacterium tuberculosis. Although TB has been described since antiquity, being diagnosed about 100 years and has treatment from the 40s, is currently still considered a serious public health problem, being reported annually 1.1 million death

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26

Cassagne, Carole. "Identifications de champignons d'intérêt médical en mycologie et parasitologie par spectrométrie de masse de type MALDI-TOF : applications au diagnostic des infections fongiques." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM5064.

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L’avènement de la spectrométrie de masse de type MALDI-TOF a révolutionné la microbiologie en permettant l’identification précise des bactéries et des levures en seulement quelques minutes. En 2010, la MALDI-TOF SM n’était pas applicable à l’identification des champignons filamenteux. Un protocole d’identification générant des spectres interprétables de champignons filamenteux fut d’abord mis au point, suivi par le développement d’une architecture de banque originale. Enfin une banque de références solides, intégrant des références pour la majorité des espèces de moisissures impliquées en path

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27

Bucci, Robert Joseph. "Molecular based identification of wood decay fungi from two field sites in Mississippi." Master's thesis, Mississippi State : Mississippi State University, 2008. http://library.msstate.edu/etd/show.asp?etd=etd-06182008-141603.

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28

Santos, Patrícia Resplandes Rocha dos. "Patogenicidade de fungos associados à sementes de andropogon e caracterização morfológica e molecular de Curvularia lunata." Universidade Federal do Tocantins, 2016. http://hdl.handle.net/11612/384.

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O Andropogon L. é uma gramínea forrageira, amplamente distribuída em áreas de Cerrado e com períodos de seca prolongada. Apresenta características de ser denso com grandes touceiras e com inflorescência plumosa, tendo uma elevada capacidade na disseminação de suas sementes. Por sua vez, as sementes são consideradas principais fontes de abrigo e transporte de agentes patogênicos para áreas livres de doenças. No Tocantins, não há registros de trabalhos que relacionem a incidência de fungos em sementes de Andropogon como causadores de doenças em culturas de importância agrícola. Da mesma forma, n

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29

Svensson, Tobias. "Infectious and bleeding complications in patients with hematological malignancies : Studies on diagnosis and prevention." Doctoral thesis, Uppsala universitet, Hematologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-316461.

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The overall aim of this thesis is to improve knowledge about the prevention of infectious and bleeding complications in patients with hematological malignancies, primarily in those with chronic lymphocytic leukemia (CLL) and myelodysplatic syndrome (MDS). Hypogammaglobulinemia, impaired production of immunoglobulins (Ig), is an established risk factor for infection, but the impact of IgG pure subclass deficiency (IgG subclass deficiency with adequate production of IgG, IgA, and IgM) has been debated. In a retrospective single institution study, we concluded that pure IgG subclass deficiency in

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30

BARBOSA, LUANA. "DIAGNÓSTICO AMBIENTAL DA BACIA DO CÓRREGO BAIXA FUNDA EM ARAGUAÍNA – TO." Pontifícia Universidade Católica de Goiás, 2018. http://tede2.pucgoias.edu.br:8080/handle/tede/3967.

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Submitted by admin tede (tede@pucgoias.edu.br) on 2018-05-10T17:08:58Z No. of bitstreams: 1 LUANA BARBOSA 1.pdf: 2486825 bytes, checksum: 885c15dce91c22870f7b1742cfae2a55 (MD5)<br>Made available in DSpace on 2018-05-10T17:08:58Z (GMT). No. of bitstreams: 1 LUANA BARBOSA 1.pdf: 2486825 bytes, checksum: 885c15dce91c22870f7b1742cfae2a55 (MD5) Previous issue date: 2018-03-01<br>The environmental impact of a river basin is responsible for most socio-environmental problems of a municipality, since water resources are intrinsic to urbanization. This work aims to perform an environmental diagnosis

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31

Carvalho, Luísa Isabel Correia. "Aspergillus e aspergilose: desafios no combate da doença." Master's thesis, [s.n.], 2013. http://hdl.handle.net/10284/4166.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>Aspergillus spp são onipresentes no ar, no solo e em material em decomposição. Como resultado estão constantemente a ser inalados, sendo assim, o trato respiratório o portal de entrada. Várias espécies de Aspergillus podem causar doenças em humanos sendo os mais frequentemente isolados: Aspergillus niger, Aspergillus nidulans, Aspergillus terreus, Aspergillus flavus e, com maior predomínio a espécie Aspergillus fumigatus. A expo

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32

Bueno, Cassiara Regina Noventa Correa. "Infecção por Sporisorium scitamineum em cana-de-açúcar: influência de variáveis ambientais e desenvolvimento de método para diagnose precoce." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/11/11135/tde-17092010-164620/.

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O carvão é uma das doenças mais importantes da cana-de-açúcar. Grande parte dos Programas de Melhoramento Genético dessa cultura utiliza inoculações artificiais para selecionar e caracterizar as variedades quanto a sua resistência a doenças. Assim o conhecimento das condições favoráveis para infecção torna-se indispensável. Neste trabalho foram estudadas as condições que afetam a infecção de gemas pelo fungo Sporisorium scitamineum. Do ponto de vista do hospedeiro foi avaliada a incidência de chicotes para diferentes idades das gemas e das brotações das variedades NA56-79, SP71-1406 e SP84-206

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33

Miloš, Pajić. "Klinički značaj načina određivanja torakalnih indeksa u dijagnostici i terapijskom tretmanu pektus ekskavatuma kod dece." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2016. http://www.cris.uns.ac.rs/record.jsf?recordId=101462&source=NDLTD&language=en.

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Cilj: Proveriti da li je moguće promeniti način CT verifikacije Hallerovog indeksa u okviru preoperativne pripreme pacijenata sa deformitetom grudnog ko&scaron;a po tipu pectus excavatum-a, uz utvrđivanje fiziolo&scaron;kog opsega vrednosti indeksa, njegove zavisnosti od uzrasta i pola, kao i respiratorne faze u kojoj se CT pregled izvodi. Utvrditi značaj vrednosti indeksa korekcije, indeksa asimetrije i indeksa torzije sternuma. Proveriti i mogućnost smanjivanja efektivne doze jonizujućeg zračenja kod primene CT tehnike jednog skena (single slice). Materijal i metod rada: Ispitivanje se sasto

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34

Seghiri, Meriem. "Les monuments funéraires en Afrique du Nord : l'étude et la mise en valeur du mausolée royal numide Medracen." Thesis, Paris 10, 2018. http://www.theses.fr/2018PA100172.

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La carte archéologique de l’Afrique du Nord est parsemée de sites et monuments funéraires d’une richesse inestimable, qui couvrent différentes périodes allant de la préhistoire à l’époque contemporaine. Cette frange riche en enseignement, est sujet à de multiples facteurs de dégradation et quasiment omise dans les opérations de sauvegarde menées jusqu’à nos jours, hormis quelques-uns. Une fois détruit, cette catégorie du patrimoine n’est pas renouvelable, il est impératif de la mettre en valeur et de veiller à sa conservation afin d’assurer la continuité entre passé, présent et avenir.Cette pr

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González, Domínguez Elisa. "Biology, epidemiology and control of Fusicladium eriobotryae, causal agent of loquat scab." Doctoral thesis, Universitat Politècnica de València, 2014. http://hdl.handle.net/10251/38715.

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El moteado del níspero, causado por el hongo Fusicladium eriobotryae es la principal enfermedad que afecta al cultivo del níspero, produciendo pérdidas importantes en la cosecha en los años con condiciones climáticas adecuadas. Sin embargo, no existen estudios sobre la epidemiología y el control de esta enfermedad, por lo que éstos constituyen el principal objetivo de la presente Tesis. Para ello, se va ha caracterizar in vitro y en campo la influencia de las principales variables climáticas en el desarrollo de F. eriobotryae, desarrollándose ecuaciones matemáticas que modelicen esta relación.

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Avella, Vasquez Ana Catalina. "Substances polymériques extracellulaires dans les procédés de traitement des eaux usées." Thesis, Vandoeuvre-les-Nancy, INPL, 2010. http://www.theses.fr/2010INPL029N/document.

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L’objectif de ce travail est d’une part (i) étudier le comportement de la biomasse notamment la production d’EPS en présence des composés pharmaceutiques (un agent anticancéreux et cinq antibiotiques); et d’autre part, (ii) étudier les EPS dans le contexte de décantation des boues en présence d’agents fongiques et en situations réelles dans des stations d’épuration. L’étude en présence de l’agent anticancéreux a été réalisée dans des bioréacteurs à membranes. La présence de l’agent anticancéreux a induit l’augmentation de la production d’EPS agissant comme un mécanisme de protection microbienn

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Seng, Piseth. "Application de la spectrométrie de masse MALDI-TOF en microbiologie clinique." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM5033/document.

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L'objectif de cette thèse est d'appliquer la méthode d'identification bactérienne par spectrométrie de masse MALDI-TOF pour une utilisation en routine dans un laboratoire de microbiologie clinique. Dans un 1er temps et de manière prospective, nous avons évalué la performance et le coût-efficacité de l'identification bactérienne de routine par MALDI-TOF par rapport aux techniques conventionnelles d'identification phénotypique. Durant la période des 16 semaines d'étude, nous avons comparé la performance de la technique par MALDI-TOF aux techniques conventionnelles d'identification phénotypique c

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Carvalho, Agostinho Albérico Rodrigues de. "Management of fungal infections: diagnosis and human genetic susceptibility." Doctoral thesis, 2008. http://hdl.handle.net/1822/8163.

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Tese de Doutoramento Ciências da Saúde - Ciências Biológicas e Biomédicas<br>Invasive fungal infections represent nowadays a major public health problem with associated high mortality rates. The lack of adequate diagnostic methods, together with the fact that many emerging fungal species are resistant to the currently available antifungal agents, contributes to the profound impact of these diseases in the health care systems, especially when dealing with immunocompromised patients. Taking this into consideration, the development of novel diagnostic applications has been considered a critic

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Pereira, Joana Isabel Carvalho. "Fighting fungal infections: development of a new diagnosis method and a novel antifungal treatment." Doctoral thesis, 2020. http://hdl.handle.net/1822/77085.

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Programa Doutoral em Biologia Molecular e Ambiental (Especialidade em Biologia Celular e Saúde)<br>A incidência das infeções fúngicas invasivas (IFI) tem aumentado significativamente devido ao desenvolvimento de intervenções médicas cada vez mais agressivas, aumentando o número de indivíduos imunocomprometidos. Candida spp. e Aspergillus spp. são os organismos mais frequentemente presentes, contudo, nos últimos anos a incidência de Rhizopus spp. tem aumentado. A eficácia do tratamento das IFI depende da suscetibilidade ao agente antifúngico utilizado e varia com a espécie. Assim, a corret

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Tshabalala, Nhlanhla. "Examination of Candida albicans strains for cytotoxicity principles with particular reference to gliotoxin production." Thesis, 2010. http://hdl.handle.net/10210/3126.

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M. Tech.<br>Yeast such as Candida albicans are the major cause of human diseases such as genital thrush and oral thrush. Some of the genital isolates of C. albicans that were studied by Shah et al. (1991 & 1995) were found to produce the medically important immunosuppressing mycotoxin gliotoxin, which has potential important medical consequences. The biosynthesis of this mycotoxin is regulated and expressed by the presence of the gliP and gliZ genes, which were identified on the putative gene cluster of A. fumigatus. Most Candidal infections are treated using a single or a combination of antif

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Fry, Christian Theodor. "Experimental infection models and diagnosis of epizootic ulcerative syndrome in three-spot gourami (Trichogaster trichopterus) and rainbow trout (Oncorhynchus mykiss)." Thesis, 2014. http://hdl.handle.net/10210/11352.

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M.Sc. (Zoology)<br>Aphanomyces invadans is an oomycete associated with epizootic ulcerative syndrome (EUS). It affects more than a 100 freshwater and estuarine species of fish and is a serious threat to aquaculture and natural aquatic ecosystems. Currently, cases of EUS have been reported across Asia, Australia, North America and more recently Southern Africa. Outbreaks occur mostly during periods of sudden temperature change, such as heavy rainfall or change of seasons. These conditions favour sporulation of A. invadans, and low temperatures have been shown to delay the inflammatory response

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Tseng, Ting-Ting, and 曾婷婷. "A Study on Fungus Diagnosis and Improvement methods of Building Materials in Taiwan." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/zbq6wg.

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碩士<br>國立臺北科技大學<br>建築與都市設計研究所<br>101<br>The high temperature and high humidity in Taiwan is suitable for the growth of fungus. To a human body, the infection of fungus may cause various diseases including allergies, rhinitis, asthma, dermatosis, athlete’s foot and keratitis. According to statistics, the fungus indoor in Taiwan mainly comes from building materials used for interior de-sign, such as wood, calcium silicate board, gypsum board and general coating. The sur-face and back of the building materials are water absorbable, so moisture is easily kept in. Also, they are not fungus-proof, wh

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Torp-Patragst, Björn. "Untersuchungen an Flavonsäurederivaten mit hoher ß-Glukanaffinität." Doctoral thesis, 2002. http://hdl.handle.net/11858/00-1735-0000-0006-B0C0-5.

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