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Дисертації з теми "Guinea pig. Trachea"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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1

Johnston, Richard A. "Characterization of the airway epithelial bioelectric mechanisms associated with the effects of epithelium-derived relaxing factor in guinea-pig isolated trachea." Morgantown, W. Va. : [West Virginia University Libraries], 2000. http://etd.wvu.edu/templates/showETD.cfm?recnum=1776.

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Thesis (Ph. D.)--West Virginia University, 2000.<br>Title from document title page. Document formatted into pages; contains ix, 135 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 127-135).

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2

MagalhÃes, Pedro Jorge Caldas. "Estudo farmacologico do Ãleo essencial do Croton nepetaefolius Baill sobre os musculos lisos traqueal e vascular e sobre as propriedades eletrofisiologicas de neuronios fasicos de ganglio celiaco." Universidade Federal do CearÃ, 2002. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=50.

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FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Estudo farmacolÃgico do Ãleo essencial de Croton nepetaefolius Baill. sobre o mÃsculo liso traqueal e vascular e sobre as propriedades eletrofisiolÃgicas de neurÃnios fÃsicos de gÃnglio celÃaco. Pedro Jorge Caldas MagalhÃes, Tese de Doutorado em Farmacologia, UFC, 2002. Croton nepetaefolius Baill Ã um arbusto aromÃtico do Nordeste brasileiro, conhecido como âmarmeleiro sabiÃâ, utilizado na medicina popular como antiespasmÃdico e carminativo. Os principais con

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3

Yang, Quan. "Modulation of endothelin production and metabolism in guinea-pig cultured tracheal epithelial cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ26624.pdf.

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4

Dodd, Sara. "Hydrodynamic and hydrogel properties of mucins from cultured guinea-pig tracheal epithelial cells." Thesis, University of Nottingham, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287166.

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5

Rodrigues, Rochana. "Análise morfológica do epitélio respiratório e avaliação radiológica do trato respiratório de cobaias (Cavia porcellus) mantidas sob diferentes sistemas de ventilação." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/10543.

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Na última década, o uso de sistemas microventilados (sistema VMA) em biotérios possibilitou alojar animais com melhor qualidade sanitária devido ao maior controle ambiental fornecido por esses sistemas. Contudo, ainda é necessária uma melhor avaliação, principalmente no que tange às respostas dos animais. Dessa forma, o objetivo deste trabalho foi avaliar a integridade do aparelho respiratório (pulmões e traquéia) de cobaias mantidas sob dois sistemas de ventilação diferentes: ventilação geral diluídora (VGD) ou ventilação para conforto e ventilação microambiental (VMA). Foram utilizados quatr

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6

Wang, Han-Lang, and 王漢琅. "Relaxant Effect of 3-Methylquercetin in Isolated guinea Pig Trachea." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/75119916337261259354.

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碩士<br>台北醫學大學<br>醫學研究所<br>83<br>3-Methylquercetm (3-MQ) had relaxant effects in guinea pig trachealis. Its IC50 was 13.98±2.54 (n=7), 14.56±0.92 (n=6) and 21.15 ± 2.92 (n=9) μM for the precontractions induced by histamine (30 μM), carbachol (0.2 μM) and isotonic KC1 (17.5 mM), respectively. There was no significant difference among them. It shows that 3-MQ has no special selectivity to these three contractile agents. Pretreatment of tracheahs with 3-MQ (30 μM) for 20 min non- competitively inhibited the contractions induced by cumulative histamine. Its calculated pD2' value was 5.29 ±0.

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7

Chen, Wang-Chen, and 陳婉真. "The possible mechanism of butylidenephthalide induced contraction in guinea-pig isolated trachea." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/04871763213695986075.

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碩士<br>台北醫學院<br>天然物醫學研究所<br>81<br>Butylidenephthalide(Bdph) 是由中國川芎中性油分離的主要抗痙成份，其抗痙作用已被證實是非專一性 (nonspecific)，然而 Bdph (30∼ 300 μM) 對離體天竺鼠氣管會引起統計上有意義的收縮作用，且此收縮在 indomethacin (2.8 μM) 的存在下，不受atropine (1 μM)、 FPL 55712 (1 μM)、 pyrila- mine (1 或 10 μM)、methysergide (1 μ M)、α- chymotrypsin (2 U/ml) 的影響，顯示 Bdph 引起氣管收縮的作用並非經由cholinergic 興奮，也非經由媒介物如 leukotrienes、 histamine、 serotonin 及tachykinins 或 prostaglandins 之受器活化所引起。然而鉀通道開啟劑 cromakalim 3 μM 有意義地拮抗 Bdph 引起的氣管收縮，

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8

Zhou, Dun Sui, and 周敦穗. "Studies on the mechanisms of cooling induced responses in isolated guinea-pig trachea." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/19828060177191793035.

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9

Chen, Junn-Lian, and 陳俊良. "Relaxant Effect of flavonoids in isolated guinea-pig trachea and their structure-activity relationship." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/27602209869459258077.

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碩士<br>台北醫學院<br>天然物醫學研究所<br>84<br>The tracheal relaxant activities and action mechanisms of flavonoids, including various classes such as flavones (i.e. flavone and apigenin), flavonols (i.e. flavonol), isoflavones (i.e. genistein), flavanones (i.e. naringenin) and chalcones (i. e. chalcone) were analyzed to understand their structure- activity relationship (SAR). The above six flavonoids dose- dependently relaxed the histamine (30 μM)-, carbachol (0.2 μ M)-, KCl (30 mM)-, and leukotriene D4

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10

Chien-Bang, Lei, and 雷建邦. "Relaxant effects of petasins, ingredients of Petasites formosanus Kitamura in isolated guinea-pig trachea." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/10161181029062773291.

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碩士<br>台北醫學院<br>藥學研究所<br>86<br>Four petasins, including petasin, iso-petasin, S-petasin and iso-S-petasin, we re isolated from Petasites formosanus Kitamura. They concentration-dependently relaxed histamine (10 *M)-, carbachol (0.2 *M)-, KCl (30 mM)- or leukotriene D4 (10 nM)-induced precontractions of isolated guinea-pig trachealis. Iso-S-pe tasin selectively relaxed carbachol- and KCl-induced precontractions, although S-petasin non-selectively relaxed the precontractions induced by these contra ctile agents. Their

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11

Liu, Pi-Ying, and 劉璧瑩. "Relaxant effects of 3,7,4'-Trihydroxyflavones in Isolated Guinea Pig Trachea and Their Structure-Activity Relationship." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/53947777070911075929.

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碩士<br>台北醫學大學<br>醫學研究所<br>83<br>Fisetin, kaempferol, quercetin, myricetin and morin are 3,7,4'-trihydroxyflavone derivatives. Fisetin, kaempferol and quercetin dose-dependently relaxed histamine (30 μM)-, carbachol(0.2 μM) -and isotonic KCl(17.5 mM)-induced precontractions in isolated guinea-pig trachea. It showed the ability of kaempferol or quercetin on tracheal relaxation was less than that of fisetin. but larger than that of myricetin or morin, as a result of comparison among their IC50 values. It shows if the proton at position of 5, 2' or 5' is substituted by OH group, the relaxant ac

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12

Kuo, Shih-Wu, and 郭世武. "Relaxant effects of quercetin methyl ether derivatives in isolated guinea-pig trachea and their structure-activity relationships." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/36908267450568829461.

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碩士<br>台北醫學院<br>醫學研究所<br>85<br>The tracheal relaxant activities and action mechanisms of quercetin methyl ether derivatives, including quercetin 4'-methyl ether (tamarixetin), quercetin 3,4',7-trimethyl ether (ayanin), quercetin 3,3',4',7-tetramethyl ether (QTME) and quercetin 3,3',4',5,7-pentamethyl ether (QPME) were analyzed and compared with our previous studies of quercetin and quercetin 3-methyl ether to understand their structure-activity relationship (SAR). The above querce\9?methyl e

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13

Chih-Hsien, Shih, and 施志賢. "Calcium channel subtypes for cholinergic and non-adrenergic non-cholinergic neurotransmission in the isolated guinea-pig trachea." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/15691219016239188311.

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碩士<br>台北醫學院<br>醫學研究所<br>86<br>1. The Ca2+ channel subtypes of the neurotransmission of isolated guinea-pig trachea were elucidated by monitoring the effects of specific Ca2+ channel blo ckers on the cholinergic contraction and non-adrenergic non-cholinergic (NANC) relaxation elicited by electrical field stimulation (EFS).2. In the isolated guinea-pig trachea, the cholinergic contractile responses to low and high fre quency of EFS were inhibited by both N-type calcium channel blockers, ω-conot oxin GVIA and ω-cono

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14

Lin, Chin-hsiu, and 林錦秀. "Effects and Mechanisms of glyceryl nonivamide and sodiumnonivamide acetate on the Tracheal Smooth Muscle in Guinea Pig." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/q3hub8.

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碩士<br>高雄醫學院<br>醫學研究所<br>87<br>The effects of glyceryl nonivamide (GLNVA) and sodium nonivamide acetate (SNA) on isolated tracheal smooth muscle of guinea-pig in vitro and the desensitizing effect of GLNVA and SNA in anesthetized guinea-pig airways in vivo were first investigated. Both GLNVA (0.01-10 uM) and SNA (0.01-100 uM) produced concentration-dependent contraction in the isolated guinea-pig trachea, and this effect were inhibited by pretreatment with capsazepine (10 uM), ruthenium red (10 uM), theophylline (10 uM), or sensory denervation, respectively. On the other hand, at higher concent

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15

Chao, Yen-Chin, and 趙彥欽. "Studies on Asthmatic Chinese Medicine Ⅱ Effect of Geniposide on Tracheal Permeability of Guinea Pigs and Its Pharmacokinetics." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/55374278184704764146.

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碩士<br>台北醫學大學<br>生藥學研究所<br>83<br>Asthma is a common disease of airway inflammation, and smite one of the important pathological manifestation is increased airway epithelial permeability. Due to the penetration of the allergens from airway lumen through tracheal epithelia, it causes mucus plugging and eosinophil infiltration by release mediators of as well as the damage to airway epithelial tissue. Therefore decreasing epithelial permeability, it could improve asthmatic tissue injuries and reduce asthmatic symptoms. Geniposide, a major component from Gardenia jasminoides Ellis, has been used

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