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Готові списки джерел за темами / Haplotype analysi

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Добірка наукової літератури з теми "Haplotype analysi"

Автор: Grafiati

Опубліковано: 11 березня 2023

Оновлено: 31 липня 2025

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Статті в журналах з теми "Haplotype analysi"

1

Kesik, Harun Kaya, Figen Celik, Seyma Gunyakti Kilinc, et al. "Genetic Diversity and Haplotype Analysis of Cattle Hydatid Cyst Isolates Using Mitochondrial Markers in Turkey." Pathogens 11, no. 5 (2022): 519. http://dx.doi.org/10.3390/pathogens11050519.

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Echinococcus granulosus sensu lato (s.l.) causes cystic echinococcosis in ungulates and humans. The current study was designed to find the genetic diversity and haplotypic profiles of hydatid cysts from the lungs of cattle in three provinces in eastern Turkey. Individual cyst isolates (n = 60) were collected from infected cattle lungs after slaughter and then samples were stored in ethanol (70%) until further use. From each isolate, total gDNA was extracted from the cysts’ germinal layers. A partial (875 bp) mt-CO1 gene was amplified by PCR and sequenced unidirectionally. The final size of the

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2

Epifanio, John M., Bonnie L. Brown, Peter E. Smouse, and Carol J. Kobak. "Mitochondrial DNA divergence among popylations of American shad (Alosa sapidissima): how much variation is enough for mixed-stock analysis?" Canadian Journal of Fisheries and Aquatic Sciences 52, no. 8 (1995): 1688–702. http://dx.doi.org/10.1139/f95-761.

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We investigated the geographic distribution of the mitochondrial DNA (mtDNA) diversity of American shad from 15 North American rivers in 1992 with the intent of assessing sampling efficiency for future mixed-stock analysis. We observed 116 haplotypes among the 988 individuals assayed. Because no single or group of haplotypes completely discriminated river stocks or regional complexes, we investigated haplotype frequencies as stock descriptors. Analysis of four unique indices of haplotype divergence indicated that including rather than suppressing restriction site heteroplasmy increased resolut

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3

Santos, Daniel Wagner C. L., Vania Aparecida Vicente, Vinicius Almir Weiss, et al. "Chromoblastomycosis in an Endemic Area of Brazil: A Clinical-Epidemiological Analysis and a Worldwide Haplotype Network." Journal of Fungi 6, no. 4 (2020): 204. http://dx.doi.org/10.3390/jof6040204.

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Chromoblastomycosis (CBM) is a neglected implantation mycosis prevalent in tropical climate zones, considered an occupational disease that affects impoverished rural populations. This retrospective study described clinical aspects of CBM in a hyperendemic area in Brazil and constructed a worldwide haplotype network of Fonsecaea spp. strains. The variables were collected from medical records using a standard report form, reporting 191 patients with CBM from Maranhão, Brazil. The mean age was 56.1 years, 168 (88%) patients were male and predominantly farmers (85.8%). The mean time of evolution o

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4

Kaul, Noyonika, Prem Lal Kashyap, Sudheer Kumar, Deepti Singh, and Gyanendra Pratap Singh. "Genetic Diversity and Population Structure of Head Blight Disease Causing Fungus Fusarium graminearum in Northern Wheat Belt of India." Journal of Fungi 8, no. 8 (2022): 820. http://dx.doi.org/10.3390/jof8080820.

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Head blight or scab caused by Fusarium graminearum (FG), once ranked as a minor disease in wheat, is now emerging as one of the economically important diseases in India. The present study represents the first in-depth population genetic analysis of the FG from the northern wheat belt of India. In this study, multiple conserved gene sequences comprised of β-tubulin (TUB), translation elongation factor 1-α (TEF), and histone-3 (HIS) regions were used for multi-locus phylogenetic analysis of 123 geographically distinct F. graminearum isolates collected from four different states (Haryana (HR), Pu

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5

Bhattacharyya, Nitai Pada, Priyadarshi Basu, Madhusudan Das, et al. "Negligible Male Gene Flow Across Ethnic Boundaries in India, Revealed by Analysis of Y-Chromosomal DNA Polymorphisms." Genome Research 9, no. 8 (1999): 711–19. http://dx.doi.org/10.1101/gr.9.8.711.

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From the historically prevalent social structure of Indian populations it may be predicted that there has been very little male gene flow across ethnic boundaries. To test this finding, we have analyzed DNA samples of individuals belonging to 10 ethnic groups, speaking Indo-European or Austroasiatic languages and inhabiting the eastern and northern regions of India. Eight Y-chromosomal markers, two biallelic and six microsatellite, were studied. All populations were monomorphic for the deletion allele at the YAP (DYS287) locus and for the 119-bp allele at the DYS288 locus. Y-chromosomal haplot

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6

Quan Ke Thai, Tuan Thanh Nguyen, and Hien Thi Thanh Pham. "mtDNA haplotype network analysis: Exploring genetic relationships and diversity in dog haplogroups." GSC Biological and Pharmaceutical Sciences 24, no. 1 (2023): 224–32. http://dx.doi.org/10.30574/gscbps.2023.24.1.0284.

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The genetic diversity and relationships of dog haplogroups were studied by analyzing the HV1 region of mitochondrial DNA. Previous studies have found six distinct haplogroups (A, B, C, D, E, and F) in dogs. Haplogroups A, B, and C were widely distributed, while haplogroups D, E, F were rare and distributed in restricted regions. In this study, HV1 sequences from global dog populations were collected, categorized into haplotypes, and used to construct haplotype networks. The results showed that haplogroup A was the most prevalent, comprising approximately 72.34% of dogs worldwide. Haplogroups A

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7

Quan, Ke Thai, Thanh Nguyen Tuan, and Thi Thanh Pham Hien. "mtDNA haplotype network analysis: Exploring genetic relationships and diversity in dog haplogroups." GSC Biological and Pharmaceutical Sciences 24, no. 1 (2023): 224–32. https://doi.org/10.5281/zenodo.8265409.

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Анотація:

The genetic diversity and relationships of dog haplogroups were studied by analyzing the HV1 region of mitochondrial DNA. Previous studies have found six distinct haplogroups (A, B, C, D, E, and F) in dogs. Haplogroups A, B, and C were widely distributed, while haplogroups D, E, F were rare and distributed in restricted regions. In this study, HV1 sequences from global dog populations were collected, categorized into haplotypes, and used to construct haplotype networks. The results showed that haplogroup A was the most prevalent, comprising approximately 72.34% of dogs worldwide. Haplogroups A

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8

Vathipadiekal, Vinod, Abdulrahman Alsultan, John Farrell, et al. "Polymorphisms Associated with the Arab-Indian Haplotype of Sickle Cell Anemia Are Candidate Fetal Hemoglobin Gene Modulators." Blood 126, no. 23 (2015): 3388. http://dx.doi.org/10.1182/blood.v126.23.3388.3388.

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Abstract Fetal hemoglobin (HbF) inhibits HbS polymerization. Because of this, sufficient HbF in most sickle erythrocytes can lead to a milder disease phenotype. HbF levels differ amongst the β-globin gene (HBB) cluster haplotypes of sickle cell anemia. In the Arab-Indian (AI) haplotype, HbF was about 20% compared with 5-10% in the Bantu, Benin, and Senegal haplotypes. Functional elements linked to the HBB haplotype are likely to regulate the expression of HbF in addition to the effects of trans-acting modulators. To identify cis-acting SNPs in the HBB gene cluster that differentiate the AI hap

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9

Tjensvoll, Kjersti, Ove Bruland, Ylva Floderus, Øyvind Skadberg, Sverre Sandberg, and Jaran Apold. "Haplotype Analysis of Norwegian and Swedish Patients with Acute Intermittent Porphyria (AIP): Extreme Haplotype Heterogeneity for the Mutation R116W." Disease Markers 19, no. 1 (2003): 41–46. http://dx.doi.org/10.1155/2003/384971.

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Acute intermittent porphyria (AIP), the most common of the acute porphyrias, is caused by mutations in the gene encoding hydroxymethylbilane synthase (HMBS) also called porphobilinogen deaminase (PBGD). The mutation spectrum in the HMBS gene is characterized by a majority of family specific mutations. Among the exceptions are R116W and W198X, with high prevalence in both the Dutch and Swedish populations. These two mutations were also detected in unrelated Norwegian patients. Thus, Norwegian and Swedish patients were haplotyped using closely linked flanking microsatellites and intragenic singl

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TAN, QIHUA, LENE CHRISTIANSEN, KAARE CHRISTENSEN, et al. "Haplotype association analysis of human disease traits using genotype data of unrelated individuals." Genetical Research 86, no. 3 (2005): 223–31. http://dx.doi.org/10.1017/s0016672305007792.

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Haplotype inference has become an important part of human genetic data analysis due to its functional and statistical advantages over the single-locus approach in linkage disequilibrium mapping. Different statistical methods have been proposed for detecting haplotype – disease associations using unphased multi-locus genotype data, ranging from the early approach by the simple gene-counting method to the recent work using the generalized linear model. However, these methods are either confined to case – control design or unable to yield unbiased point and interval estimates of haplotype effects

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Більше джерел

Дисертації з теми "Haplotype analysi"

1

Waldron, Edward. "Analysis of genetic association studies via haplotype clustering." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497253.

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Tai, Bik-wah Diana, and 戴碧華. "Haplotype analysis of the family with Lynch syndrome." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45153772.

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Yatskiv, Yuriy Romanovich. "A Haplotype Analysis of an Archaic Denisovan Genome." University of Toledo Health Science Campus / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=mco1481145733356233.

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4

Zhao, Jiantao. "Combining Association and Haplotype Studies Towards the Improvement of Fruit Quality in Tomato Multiple haplotype-based analyses provide genetic and evolutionary insights into tomato fruit weight and composition Meta-analysis of genome-wide association studies provides insights into genetic control of tomato flavor Genomic designing for climate smart tomato." Thesis, Avignon, 2019. http://www.theses.fr/2019AVIG0712.

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Анотація:

Les consommateurs se plaignent de la qualité gustative des tomates depuis des décennies. Celle-ci est influencée principalement par les sucres, les acides et un ensemble de divers composés volatils. L’amélioration de la saveur de la tomate reste l’un des principaux défis à relever pour améliorer la qualité de la tomate et l’acceptabilité des consommateurs pour l’amélioration moderne des tomates. Le but principal de cette thèse était de disséquer le contrôle génétique de la saveur de la tomate en utilisant des SNP à haute densité et un ensemble divers de traits liés à la saveur, notamment les s

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Lächelt, Sandra [Verfasser]. "Funktionelle Analyse von ABCC2-Haplotypen / Sandra Lächelt." Kiel : Universitätsbibliothek Kiel, 2009. http://d-nb.info/1019869933/34.

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Hughes, David J. "Mutation characterisation and microsatellite haplotype analysis of the CFTR gene." Thesis, Queen's University Belfast, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361278.

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Osman, Abdimajid. "Studies on warfarin treatment with emphasis on inter-individual variations and drug monitoring." Doctoral thesis, Linköping : Linköping University, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/med1000s.pdf.

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ROSA, Rogério dos Santos. "Associating genotype sequence properties to haplotype inference errors." Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/16011.

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Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2016-03-16T15:28:47Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) RogerioSantosRosa_Tese.pdf: 1740026 bytes, checksum: aa346f64c34419c4b83269ccb99ade6a (MD5)<br>Made available in DSpace on 2016-03-16T15:28:48Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) RogerioSantosRosa_Tese.pdf: 1740026 bytes, checksum: aa346f64c34419c4b83269ccb99ade6a (MD5) Previous issue date: 2015-03-12<br>Haplotype information has a cen

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Nettelblad, Carl. "Two Optimization Problems in Genetics : Multi-dimensional QTL Analysis and Haplotype Inference." Doctoral thesis, Uppsala universitet, Avdelningen för beräkningsvetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-180920.

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The existence of new technologies, implemented in efficient platforms and workflows has made massive genotyping available to all fields of biology and medicine. Genetic analyses are no longer dominated by experimental work in laboratories, but rather the interpretation of the resulting data. When billions of data points representing thousands of individuals are available, efficient computational tools are required. The focus of this thesis is on developing models, methods and implementations for such tools. The first theme of the thesis is multi-dimensional scans for quantitative trait loci (Q

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Neville, Catherine E. "The high resolution haplotype analysis and origin of the myotonic dystrophy mutation." Thesis, University of Ottawa (Canada), 1994. http://hdl.handle.net/10393/9857.

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The objective of this thesis was to determine the origin of the myotonic dystrophy (DM) mutation. I have used PCR-based assays of nine polymorphisms spanning a physical distance of 30 kb, within and immediately flanking the DM kinase gene, in order to examine patterns of allelic association with respect to the DM mutation. Four main haplotypes (A-D) were observed in the normal population using these nine markers at the DM locus. Significantly, DM is in complete association with haplotype A, the most common haplotype in the normal population. Our data suggest the presence of two founding chromo

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Книги з теми "Haplotype analysi"

1

Pound, Michelle C. Deletion screening and haplotype analysis in the Fraxe region at Xq28. [University of Portsmouth], 2000.

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2

Männikkö, Minna. Congenital nephrotic syndrome of the Finnish type: Refined mapping of the gene locus on chromosome 19q13.1 and haplotype analysis. University of Oulu, 1996.

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3

Mészáros, Gábor, Marco Milanesi, Paolo Ajmone Marsan, and Yuri Tani Utsunomiya, eds. Haplotype Analysis Applied to Livestock Genomics. Frontiers Media SA, 2021. http://dx.doi.org/10.3389/978-2-88966-968-4.

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4

Waterman, Michael, Clark Andrew, and Sorin Istrail. Computational Methods for SNPs and Haplotype Inference: DIMACS/RECOMB Satellite Workshop, Piscataway, NJ, USA, November 21-22, 2002, Revised Papers. Springer London, Limited, 2004.

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5

Crawford, Michael, and Rohina C. Rubicz. Molecular Genetic Evidence from Contemporary Populations for the Origins of Native North Americans. Edited by Max Friesen and Owen Mason. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199766956.013.4.

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An overview of the current molecular genetic evidence for the origins of North American populations is presented, including specific examples from the authors’ work with the Aleutian Island inhabitants. Shared mitochondrial DNA and Y-chromosome DNA markers among Siberians and Native Americans point to a Pleistocene migration from Siberia into the Americas via Beringia. There was likely a later migration from Siberia to Alaska, based on the analysis of whole-genome sequence data from a Greenland Paleoeskimo that clusters this individual with Siberian populations. Coalescence date estimates for

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Lewis, Myles, and Tim Vyse. Genetics of connective tissue diseases. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0042.

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The advent of genome-wide association studies (GWAS) has been an exciting breakthrough in our understanding of the genetic aetiology of autoimmune diseases. Substantial overlap has been found in susceptibility genes across multiple diseases, from connective tissue diseases and rheumatoid arthritis (RA) to inflammatory bowel disease, coeliac disease, and psoriasis. Major technological advances now permit genotyping of millions of single nucleotide polymorphisms (SNPs). Group analysis of SNPs by haplotypes, aided by completion of the Hapmap project, has improved our ability to pinpoint causal ge

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Частини книг з теми "Haplotype analysi"

1

Martin, Marcel, Peter Ebert, and Tobias Marschall. "Read-Based Phasing and Analysis of Phased Variants with WhatsHap." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2819-5_8.

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AbstractWhatsHap is a command-line tool for phasing and phasing-related tasks. It allows to infer haplotypes in diploid and polyploid samples based on (preferably long) reads covering at least two heterozygous variants. It offers additional tools for working with phased variant calls such as computing statistics, comparing different phasings and assigning reads in alignment files to their haplotype.

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2

Delaneau, Olivier, and Jean-François Zagury. "Haplotype Inference." In Data Production and Analysis in Population Genomics. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-870-2_11.

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3

Epstein, Michael P., and Lydia C. Kwee. "Haplotype Association Analysis." In Handbook on Analyzing Human Genetic Data. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-69264-5_8.

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4

Stram, Daniel O. "Haplotype Imputation for Association Analysis." In Design, Analysis, and Interpretation of Genome-Wide Association Scans. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-9443-0_5.

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Wetmur, James G., and Jia Chen. "Linking Emulsion PCR Haplotype Analysis." In Methods in Molecular Biology. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-944-4_11.

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Zheng, Gang, Yaning Yang, Xiaofeng Zhu, and Robert C. Elston. "Haplotype Analysis for Case-Control Data." In Analysis of Genetic Association Studies. Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-2245-7_7.

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Graça, Ana, João Marques-Silva, and Inês Lynce. "Haplotype Inference Using Propositional Satisfiability." In Mathematical Approaches to Polymer Sequence Analysis and Related Problems. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6800-5_7.

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Roeder, Kathryn. "Evolutionary-Based Association Analysis Using Haplotype Data." In Computational Methods for SNPs and Haplotype Inference. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-540-24719-7_24.

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Stram, Daniel O., and Venkatraman E. Seshan. "Multi-SNP Haplotype Analysis Methods for Association Analysis." In Methods in Molecular Biology. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-555-8_23.

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Stram, Daniel O. "Multi-SNP Haplotype Analysis Methods for Association Analysis." In Methods in Molecular Biology. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7274-6_24.

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Тези доповідей конференцій з теми "Haplotype analysi"

1

Dubovskova, S. D., and A. A. Zamyatin. "VALIDATION OF A. COLUZZII AND A. GAMBIAE HYBRIDS HAPLOTYPE PHASING BY TRIO BINNING." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-2.

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Анотація:

The majority of nowadays genome assemblies are mixed haplotypes. An assembly of such haplotypes introduces DNA variants not present in any of true haplotypes, which negatively affects downstream genome analysis. Therefore, we assembled phased haplotypes of major malaria vectors in Sub-Saharan Africa using trio binning method. To validate haplotype phasing, we performed p-distance and k-mer quotient analyses. The results indicate correct haplotypes phasing.

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2

Lin, Shili, and Terence P. Speed. "An algorithm for haplotype analysis." In the first annual international conference. ACM Press, 1997. http://dx.doi.org/10.1145/267521.267548.

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3

Tejera, P., Z. Wang, R. Zhai, L. Su, CC Sheu, and DC Christiani. "Functional Analysis of Haplotypes inPI3Promoter." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1884.

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4

Sadovnychenko, Iurii, and Nataliia Pastukhova. "Open data of molecular genetic research through the prism of global trends." In First International Conference "Open Science and Innovation in Ukraine 2022". State Scientific and Technical Library of Ukraine, 2022. http://dx.doi.org/10.35668/978-966-479-129-5-7-18.

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Анотація:

The availability analysis of genetic databases in the articles of Ukrainian and foreign scientists was performed. Only 6.4 % of articles in domestic journals provided data on the subjects’ genotype and haplotype distribution. Most journals are open access, but their editorial policy does not postulate their commitment to open data sharing.

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Prokhorova, E. E., and R. R. Usmanova. "GENETIC POLYMORPHISM OF SNAILS SUCCINEA PUTRIS (GASTROPODA, PULMONATA)." In V International Scientific Conference CONCEPTUAL AND APPLIED ASPECTS OF INVERTEBRATE SCIENTIFIC RESEARCH AND BIOLOGICAL EDUCATION. Tomsk State University Press, 2020. http://dx.doi.org/10.17223/978-5-94621-931-0-2020-33.

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Genotypic diversity of snails Succinea putris L. (Linnaeus, 1758) collected in the north-west of Russia and in the Republic of Belarus was analysed. Homology between the nucleotide sequences of snails from different population made up 100% by the nucleotide sequence of ITS1-5.8S-ITS2 region of rDNA. Genetic variability based on mitochondrial markers was insignificant. Average genetic distances between samples made up 0,009 for СOI gene loci and 0.008 for CytB gene loci. Was found ten haplotypes of the mitochondrial gene CytB and nine haplotypes of the mitochondrial gene СOI. Perhaps the geneti

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Uddin, Mohammed, Mitch Sturge, Courtenay Griffin, Steve Benteau, and Proton Rahman. "Variability of haplotype phase and its effect on genetic analysis." In 2008 Canadian Conference on Electrical and Computer Engineering - CCECE. IEEE, 2008. http://dx.doi.org/10.1109/ccece.2008.4564604.

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"Analysis of SARS-CoV-2 genomic data using haplotype networks." In Биоинформатика регуляции и структуры геномов / системная биология. ИЦиГ СО РАН, 2024. http://dx.doi.org/10.18699/bgrs2024-5.2-23.

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KHRABROVA, Lyudmila A., Alexander M. ZAITSEV, Larisa L. VIKULOVA, Marina V. ADAMKOVSKAYA, Nina V. BLOKHINA, and Sergey I. SOROKIN. "MtDNA Haplotype Analysis in Dam Families of the Thoroughbred Riding Horses." In XVIII International Scientific and Practical Conference "Modern Trends in Agricultural Production in the World Economy". Sibac, 2020. http://dx.doi.org/10.32743/kuz.agri.2020.34-42.

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"Haplotype Block Analysis of FSHR Gene in Sragen and Jabres Cattle." In Technology Innovations and Collaborations in Livestock Production for Sustainable Food Systems. IAARD Press, 2021. http://dx.doi.org/10.14334/proc.intsem.lpvt-2021-p.16.

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NG, MICHAEL K., ERIC S. FUNG, WAI-KI CHING, and YIU-FAI LEE. "A RECURSIVE METHOD FOR SOLVING HAPLOTYPE FREQUENCIES IN MULTIPLE LOCI LINKAGE ANALYSIS." In 4th Asia-Pacific Bioinformatics Conference. PUBLISHED BY IMPERIAL COLLEGE PRESS AND DISTRIBUTED BY WORLD SCIENTIFIC PUBLISHING CO., 2005. http://dx.doi.org/10.1142/9781860947292_0016.

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Звіти організацій з теми "Haplotype analysi"

1

Sittipraneed, Siriporn. การศึกษาการแพร่กระจายของประชากรผึ้งโพรง Apis cerana กลุ่มตอนเหนือและตอนใต้ในบริเวณพื้นที่รอยต่อโดยใช้ดีเอ็นเอเครื่องหมาย : รายงานผลการวิจัย. Chulalongkorn University, 2002. https://doi.org/10.58837/chula.res.2002.30.

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PCR-RFLP of three mtDNA regions ( srRNA gene ,irRNA gene and intergenic COI – COII region) were used to investigated the distribution of northern and southern Apis cerana populations of 89 colonies from Prachuap Khiri Khan and Chumphon provinces. Three, four and eight haplotypes were obtained from DraI digestion of PCR-amplified 410 bp srRNA gene, 755bp IrRNA gene and 1710 bp intergenic COI-COII region,respectively. These three mtDNA regions generated 11 composit haplotypes. Twelve composite haplotypes were generated when samples from Yunnan and Hanoi were included. A UPGMA phenogram based on

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2

Roecklein, Kathryn A. Haplotype Analysis of the Melanopsin Gene in Seasonal Affective Disorder and Controls. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ad1014058.

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3

Wongpiyabovorn, Jongkonnee, Nattiya Hirankarn, Yingyos Avihingsanon, Tewin Tencomnao, Yong Poovorawan, and Kriangsak Ruchusatsawat. The association between immunogenetics and genetic susceptibility of psoriasis in Thai population. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.27.

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Psoriasis is T-cell-mediated skin autoimmunity, required environmental triggers and genetic susceptibility factors to become manifested. Psoriasis is a chronic skin disease characterized by the abnormal hyperproliferation and differentiation of the epidermis, elongated and prominent blood vessels and a thick perivascular lymphocytic infiltrate. Vascular endothelial growth factor (VEGF) gene play important role in pathogenesis of various diseases with angiogenic basis such as breast cancer and autoimmune disease including psoriasis. Many studies analyzed the association of VEGF gene polymorphis

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4

นุชประยูร, สุรางค์, จินตนา จิรถาวร, อนุพงค์ สุจริยากุล та อลิสา จันทร์ปี. การศึกษาภูมิคุ้มกันวิทยาเชิงลึกของโรคเท้าช้าง : มุ่งสู่การป้องกันภาวะเท้าช้างและการกำจัดโรคอย่างถาวร : แผนการวิจัย : รายงานการวิจัยฉบับสมบูรณ์. จุฬาลงกรณ์มหาวิทยาลัย, 2009. https://doi.org/10.58837/chula.res.2009.21.

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โรคเท้าช้าง (Lymphatic filariasis) เกิดจากพยาธิ 2 ชนิดหลัก คือ Wuchereria bancrofti และ Brugia malayi ทางองค์การอนามัยโลกได้กำหนดให้โรคเท้าช้างเป็นโรคทางปรสิตที่ควรกำจัดให้หมดไปภายในปี พ.ศ. 2563 โดยมีแนวทางหลักในการควบคุมและป้องกันโรคเท้าช้างคือการจัดให้มีโปรแกรมการรักษาแบบหมู่ โดยให้ยา diethylcarbamazine (DEC) ร่วมกับยา albendazole แก่ประชากรในพื้นที่ที่มีความชุกของโรคสูง และการควบคุมพยาธิภาวะ ปัญหาที่สำคัญของการรักษาโรคเท้าช้าง คือ การใช้ยา DEC ที่ก่อให้เกิดปฏิกิริยาหลังการรักษา กลไกของการเกิดพยาธิสภาพของโรคและการเกิดปฏิกิริยาหลังการรักษายังไม่เป็นที่ทราบแน่ชัดได้ จึงเป็นอุปสรรคที่สำคัญอย่าง

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5

Michelmore, Richard, Eviatar Nevo, Abraham Korol, and Tzion Fahima. Genetic Diversity at Resistance Gene Clusters in Wild Populations of Lactuca. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7573075.bard.

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Genetic resistance is often the least expensive, most effective, and ecologically-sound method of disease control. It is becoming apparent that plant genomes contain large numbers of disease resistance genes. However, the numbers of different resistance specificities within a genepool and the genetic mechanisms generating diversity are poorly understood. Our objectives were to characterize diversity in clusters of resistance genes in wild progenitors of cultivated lettuce in Israel and California in comparison to diversity within cultivated lettuce, and to determine the extent of gene flow, re

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6

Torrungruang, Kitti, Soranun Chantarangsu, and Thanyachai Sura. Association between vitamin D receptor gene polymorphisms and chronic periodontitis in Thais. Chulalongkorn University, 2015. https://doi.org/10.58837/chula.res.2015.18.

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Polymorphisms of the vitamin D receptor (VDR) gene have been implicated in the susceptibility to infections and bone-related diseases. However, their relationship with periodontal disease remains unclear. This cross-sectional study investigated whether the susceptibility to chronic periodontitis in a Thai population is associated with VDR polymorphisms. Genomic DNA was obtained from 1,460 subjects, aged 39-65 years. Genotyping of VDR polymorphisms (FokI, BsmI, ApaI, and TaqI) was performed using real-time polymerase chain reaction. Subjects were categorized into three groups; no/mild, moderate

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7

Sherman, Amir, Rebecca Grumet, Ron Ophir, Nurit Katzir, and Yiqun Weng. Whole genome approach for genetic analysis in cucumber: Fruit size as a test case. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7594399.bard.

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The Cucurbitaceae family includes a broad array of economically and nutritionally important crop species that are consumed as vegetables, staple starches and desserts. Fruit of these species, and types within species, exhibit extensive diversity as evidenced by variation in size, shape, color, flavor, and others. Fruit size and shape are critical quality determinants that delineate uses and market classes and are key traits under selection in breeding programs. However, the underlying genetic bases for variation in fruit size remain to be determined. A few species the Cucurbitaceae family were

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8

Fahima, Tzion, and Jorge Dubcovsky. Map-based cloning of the novel stripe rust resistance gene YrG303 and its use to engineer 1B chromosome with multiple beneficial traits. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7598147.bard.

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Research problem: Bread wheat (Triticumaestivum) provides approximately 20% of the calories and proteins consumed by humankind. As the world population continues to increase, it is necessary to improve wheat yields, increase grain quality, and minimize the losses produced by biotic and abiotic stresses. Stripe rust, caused by Pucciniastriiformisf. sp. tritici(Pst), is one of the most destructive diseases of wheat. The new pathogen races are more virulent and aggressive than previous ones and have produced large economic losses. A rich source for stripe-rust resistance genes (Yr) was found in w

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