Добірка наукової літератури з теми "Hemorrhagic conversion"

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Статті в журналах з теми "Hemorrhagic conversion"

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de Courten-Myers, Gabrielle M., Marla Kleinholz, Pat Holm, et al. "Hemorrhagic infarct conversion in experimental stroke." Annals of Emergency Medicine 21, no. 2 (1992): 120–26. http://dx.doi.org/10.1016/s0196-0644(05)80144-1.

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Dang, Jinfeng, Jieting Li, Haixia Li, Gaoyan Pian, and Zhizhuan Guo. "The Value of a Management Plan Based on Risk Factors for Cerebral Infarction Patients with Cerebral Hemorrhage." Journal of Healthcare Engineering 2022 (April 8, 2022): 1–6. http://dx.doi.org/10.1155/2022/8635487.

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Анотація:
Cerebral infarction is a neurological disease related to abnormal blood supply to brain tissue. Patients are mainly men between the ages of 50 and 60 years old. In order to explore the value of risk factor-based management programs for preventing hemorrhagic conversion in patients with cerebral infarction, this paper uses single and multifactor methods to analyze the risk factors of cerebral hemorrhage transformation after cerebral infarction and formulate risk factor-based management plans. 240 cases of cerebral infarction who were admitted to our hospital in the past 2 years were evenly divi
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Won, Soonmi, Jin Hwan Lee, Bushra Wali, Donald G. Stein, and Iqbal Sayeed. "Progesterone Attenuates Hemorrhagic Transformation after Delayed tPA Treatment in an Experimental Model of Stroke in Rats: Involvement of the VEGF–MMP Pathway." Journal of Cerebral Blood Flow & Metabolism 34, no. 1 (2013): 72–80. http://dx.doi.org/10.1038/jcbfm.2013.163.

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Tissue plasminogen activator (tPA) is the only FDA-approved treatment for acute stroke, but its use remains limited. Progesterone (PROG) has shown neuroprotection in ischemia, but before clinical testing, we must determine how it affects hemorrhagic transformation in tPA-treated ischemic rats. Male Sprague–Dawley rats underwent middle cerebral artery occlusion with reperfusion at 4.5 hours and tPA treatment at 4.5 hours, or PROG treatment intraperitoneally at 2 hours followed by subcutaneous injection at 6 hours post occlusion. Rats were killed at 24 hours and brains evaluated for cerebral hem
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Agarwal, Nitin, Giulio Zuccoli, Geoffrey Murdoch, Brian T. Jankowitz, and Stephanie Greene. "Developmental venous anomaly presenting as a spontaneous intraparenchymal hematoma without thrombosis." Neuroradiology Journal 29, no. 6 (2016): 465–69. http://dx.doi.org/10.1177/1971400916665387.

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Introduction Developmental venous anomalies (DVAs) are cited as the most common cerebral vascular malformations. Still, intracerebral hematomas are rarely thought to be caused by DVAs. In this report, the authors present a unique case of a DVA that hemorrhaged spontaneously, rather than hemorrhaging into a venous infarction following DVA thrombosis as has been more commonly reported. Clinical presentation A 22-year-old previously healthy male presented to the emergency department with a severe headache, confusion, and progressive hemiparesis. A computed tomography (CT) scan demonstrated a spon
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Khanna, Arjun, Brian P. Walcott, Kristopher T. Kahle, and J. Marc Simard. "Effect of glibenclamide on the prevention of secondary brain injury following ischemic stroke in humans." Neurosurgical Focus 36, no. 1 (2014): E11. http://dx.doi.org/10.3171/2013.10.focus13404.

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Cerebral edema and hemorrhagic conversion are common, potentially devastating complications of ischemic stroke and are associated with high rates of mortality and poor functional outcomes. Recent work exploring the molecular pathophysiology of the neurogliovascular unit in ischemic stroke suggests that deranged cellular ion homeostasis due to altered function and regulation of ion pumps, channels, and secondary active transporters plays an integral role in the development of cytotoxic and vasogenic edema and hemorrhagic conversion. Among these proteins involved in ion homeostasis, the ischemia
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Schneider, Christian P., Martin G. Schwacha, T. S. Anantha Samy, Kirby I. Bland та Irshad H. Chaudry. "Androgen-mediated modulation of macrophage function after trauma-hemorrhage: central role of 5α-dihydrotestosterone". Journal of Applied Physiology 95, № 1 (2003): 104–12. http://dx.doi.org/10.1152/japplphysiol.00182.2003.

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Androgens have been implicated as the causative factor for the postinjury immune dysfunction in males; however, it remains unknown whether androgens directly affect macrophages. To study this, male mice were sham operated or subjected to trauma (i.e., midline laparotomy) and hemorrhagic shock (mean arterial pressure, 30 ± 5 mmHg for 90 min and then resuscitated). The mice received the 5α-reductase inhibitor 4-hydroxyandrostenedione (4-OHA) before resuscitation. Plasma TNF-α, IL-6, and IL-10 levels were elevated after trauma-hemorrhage and normalized by 4-OHA. TNF-α and IL-6 production by splen
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Kim, Beom Joon, and Seung-Hoon Lee. "Silent Microbleeds and Hemorrhagic Conversion of an Embolic Infarction." Journal of Clinical Neurology 3, no. 3 (2007): 147. http://dx.doi.org/10.3988/jcn.2007.3.3.147.

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Dietzen, Anton, Anton Dietzen, Anjum Sayyad, and Susan Brady. "Anticoagulation: Hemorrhagic Conversion and VTE following Acute Ischemic Stroke." Archives of Physical Medicine and Rehabilitation 97, no. 10 (2016): e91. http://dx.doi.org/10.1016/j.apmr.2016.08.281.

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Modelska, K., M. A. Matthay, L. A. S. Brown, E. Deutch, L. N. Lu та J. F. Pittet. "Inhibition of β-adrenergic-dependent alveolar epithelial clearance by oxidant mechanisms after hemorrhagic shock". American Journal of Physiology-Lung Cellular and Molecular Physiology 276, № 5 (1999): L844—L857. http://dx.doi.org/10.1152/ajplung.1999.276.5.l844.

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Endogenous release of catecholamines is an important mechanism that can prevent alveolar flooding after brief but severe hemorrhagic shock. The objective of this study was to determine whether this catecholamine-dependent mechanism upregulates alveolar liquid clearance after prolonged hemorrhagic shock. Rats were hemorrhaged to a mean arterial pressure of 30–35 mmHg for 60 min and then resuscitated with a 4% albumin solution. Alveolar liquid clearance was measured 5 h later as the concentration of protein in the distal air spaces over 1 h after instillation of a 5% albumin solution into one lu
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Woodward, Keith, Scott Wegryn, Carla Staruk, and Eric M. Nyberg. "The Dotter method revisited: early experience with a novel method of rapid internal carotid artery revascularization in the setting of acute ischemic stroke." Journal of NeuroInterventional Surgery 8, no. 4 (2015): 360–66. http://dx.doi.org/10.1136/neurintsurg-2014-011587.

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BackgroundTandem occlusive disease in the setting of acute ischemic stroke involving cervical and cerebral arteries has been associated with poor neurological outcome and poses significant challenges to neurointerventionists. Previously described endovascular methods typically involve carotid revascularization with stent placement prior to or following intracranial thrombectomy. Stent-based approaches, however, require the use of antiplatelet therapy which may increase the risk of hemorrhagic transformation. We describe a novel modified Dotter technique which may be used for carotid revascular
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Частини книг з теми "Hemorrhagic conversion"

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Schaefer, Pamela W., and Myriam Edjlali. "Nontraumatic Intracranial Hemorrhage." In IDKD Springer Series. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-50675-8_5.

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AbstractSpontaneous ICH is usually intraparenchymal or subarachnoid in location. Intraparenchymal hemorrhages, encompassing lobar or centrally located hematomas, have diverse underlying causes, with cerebral amyloid angiopathy, characterized by lobar hemorrhage, being the most common. Hypertension is the second most common cause with a predilection for the basal ganglia, pons, and cerebellum. Subarachnoid hemorrhage is linked to aneurysm rupture in 85% of cases. Other relatively common causes of spontaneous intracranial hemorrhage include hemorrhagic conversion of ischemic infarction, cerebral
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Aydin, Ani, Daniel Joseph, and Melissa Joseph. "Acute Ischemic Stroke (AIS) with Hemorrhagic Conversion." In Simulation in EMS and Critical Care Transport. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-40090-2_24.

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Topor, F. Sigmund. "Cultural Hemorrhage of Religion and Spirituality on Healthcare and Wellness." In Religion and Theology. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-2457-2.ch019.

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Анотація:
As life approaches expectancy and senescence actualizes, the regenerative capacity of the vital organs and their functionality is reduced. Such a reality gives rise the need to identify with a better purpose in life. Religion and spirituality assume a central role in the wellness and healthcare in such circumstances. Although societies and civilizations differ in their religious and spiritual orientations, all peoples everywhere ascribe to some God or gods. The globalization of religion was initiated sometime between the late Bronze Age and late classical antiquity. The pivotal point was chara
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Topor, F. Sigmund. "Cultural Hemorrhage of Religion and Spirituality on Healthcare and Wellness." In Handbook of Research on Individualism and Identity in the Globalized Digital Age. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-0522-8.ch015.

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Анотація:
As life approaches expectancy and senescence actualizes, the regenerative capacity of the vital organs and their functionality is reduced. Such a reality gives rise the need to identify with a better purpose in life. Religion and spirituality assume a central role in the wellness and healthcare in such circumstances. Although societies and civilizations differ in their religious and spiritual orientations, all peoples everywhere ascribe to some God or gods. The globalization of religion was initiated sometime between the late Bronze Age and late classical antiquity. The pivotal point was chara
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Patriarco, Michael, Sachin Shenoy, and Nicholas Taylor. "Biologic Hemostatic Agents in Obstetrics and Gynecology." In Contemporary Applications of Biologic Hemostatic Agents across Surgical Specialties - Volume 2 [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96969.

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In Obstetrics and Gynecology, the practice of biologic hemostatic agents in the field are generally used to augment the basic tenets of hemostasis to decrease the morbidity and mortality of such procedures. These hemostatic agents work along with the body’s physiology to rapidly aid in platelet plug formation, activation of the clotting cascade, the creation of fibrin, and to form a stable clot. The four main sub-categories of hemostatic agents include mechanical, biological, flowable, and fibrin sealants. Mechanical agents act as scaffolding for platelet aggregation to form a platelet plug. B
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Тези доповідей конференцій з теми "Hemorrhagic conversion"

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Boyke, A., K. Javed, J. Dardick, et al. "E-074 Predictors of hemorrhagic conversion following mechanical thrombectomy for acute ischemic stroke (AIS)." In SNIS 18TH ANNUAL MEETING. BMJ Publishing Group Ltd., 2021. http://dx.doi.org/10.1136/neurintsurg-2021-snis.169.

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Khan, S., R. Parikh, and H. W. Farber. "Hepatic Compartment Syndrome Caused by a Subcapsular Hematoma from the Hemorrhagic Conversion of Septic Emboli in a Patient with Endocarditis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3545.

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Ferreira, Hanna dos Santos, Agata Layanne Soares da Silva, and João Lucas de Sousa Peres. "Fibrinolytic therapy in the treatment of pediatric ischemic stroke." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.033.

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Introduction: Pediatric stroke is a disorder that can result in morbidity and mortality. The ischemic type is the most common and has thrombolytics as the preferred therapy. Objective: To evaluate the therapeutic management and efficacy of fibrinolytics in pediatric patients with ischemic stroke. Methodology: The literature review was carried out in PUBMED, MEDLINE, Embase databases, with the descriptors “Fibrinolytic Agents”, “Thrombolytic Therapy”, “Ischemic Stroke”, “Stroke”, “Pediatrics” and “Treatment”. Included were clinical trials, randomized controlled trials, cohort, case- control, an
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Loscalzo, J. "THE EFFICACY AND RELATIVE FIBRIN SELECTIVITY OF PROUROKINASE IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643573.

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The use of thrombolytic agents in acute myocardial infarction has gained widespread acceptance as an important early therapeutic option. Acute coronary thrombosis has been found in approximately 80% of patients with acute infarction and the use of standard thrombolytic agents opens these occluded vessels in most cases. Unfortunately, in many individuals standard agents also produce a systemic lytic state with its attendant hemorrhagic complications. Prourokinase (PUK) has been shown to be a relatively fibrin selective thrombolytic agent in vitro owing to its localized conversion to urokinase a
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Aronis, Ze’ev, and Shmuel Einav. "Analysis of Biomechanical Forces Influencing Atherosclerotic Plaque Vulnerability." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206454.

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Cardiovascular disease has long been the leading cause of death in the western world: over 1.4 million heart attacks are suffered every year, more than half of which prove fatal. Vulnerable plaques are inflamed, active, and growing lesions which are prone to complications such as rupture, luminal and mural thrombosis, intraplaque hemorrhage, and rapid progression to stenosis. The rupture of thin fibrous cap overlying the necrotic core of a vulnerable plaque is the principal cause of acute coronary syndrome. The mechanism or mechanisms responsible for the sudden conversion of a stable atheroscl
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Massarwa, Eyass, Aronis Ze’ev, Rami Eliasy, Rami Haj-Ali, and Shmuel Einav. "Stress Concentrations of Vulnerable Plaques With a Composite Variable Core." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19233.

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Анотація:
Vulnerable plaques are inflamed, active, and growing lesions which are prone to complications such as rupture, luminal and mural thrombosis, intraplaque hemorrhage, and rapid progression to stenosis. It remains difficult to assess what factors influence the biomechanical stability of vulnerable plaques and promote some of them to rupture while others remain intact. The rupture of thin fibrous cap overlying the necrotic core of a vulnerable plaque is the principal cause of acute coronary syndrome. The mechanism or mechanisms responsible for the sudden conversion of a stable atherosclerotic plaq
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Rabin, Yoed, Thomas B. Julian, Peter Olson, Michael J. Taylor, and Norman Wolmark. "Cryosurgery for Breast Malignancies: Apparatus and Techniques." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0585.

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Abstract The treatment of breast cancer has evolved from the time of mutilation and ignorance in the middle ages, to one of breast conserving management and an intense study and understanding of the biological mechanisms driving tumor cells. As the treatment is directed to the cellular and sub-cellular level, breast conserving surgical procedures take on a more important role. Recent published results from neoadjuvant trials indicate a decrease in tumor size in 80% of patients and a modest increase in conversion from mastectomy to lumpectomy. By 2010 AD, it is estimated that 50% of all new bre
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