Готові списки джерел за темами / HT-22 cell line

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Добірка наукової літератури з теми "HT-22 cell line"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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Статті в журналах з теми "HT-22 cell line"

Qi, Huizhen, та Liang Liu. "Rhoifolin attenuates damage to hippocampal neuronal culture model of acquired epilepsy in vitro by regulating NF-κB/iNOS/COX-2 axis". Quality Assurance and Safety of Crops & Foods 14, № 3 (2022): 116–23. http://dx.doi.org/10.15586/qas.v14i3.1093.

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To assess the effect of Rhoifolin (ROF [apigenin 7-O-enneohesperidoside]) on the damage to hippocampal neu-ronal culture model of acquired epilepsy (AE) and investigate its possible mechanisms. A hippocampal neuronal culture model of AE was established through incubating HT-22 cells with MgCl2 free medium. 3-(4,5-Dimethylth-iazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assays were used to assess the effect of ROF on cell viability and apoptosis exposed to epilepsy. The oxidative stress and secretion of inflammatory cy

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Kim, Si-Yeon, Jung-Ho Lee, and Soon-Ae Kim. "Zinc Deficiency Induces Autophagy in HT-22 Mouse Hippocampal Neuronal Cell Line." International Journal of Molecular Sciences 23, no. 15 (2022): 8811. http://dx.doi.org/10.3390/ijms23158811.

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Zinc is a trace metal vital for various functions in nerve cells, although the effect of zinc deficiency on neuronal autophagy remains unclear. This study aimed to elucidate whether zinc deficiency induced by treatment with N, N, N′, N′-tetrakis (2-pyridylmethyl) ethylenediamine (TPEN), a zinc chelator, affects and alters autophagy activity. In cell viability assays, TPEN showed cytotoxicity in HT-22 cells. TPEN treatment also increased LC3-II levels and the ratio of LC3-II to LC3-I. Western blot analysis showed that phospho-AMP-activated protein kinase levels and the ratio of phospho-AMP-acti

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V., Karri, Kumar V., Ramos D., Oliveira E., and Schuhmacher M. "An in vitro cytotoxic approach to assess the toxicity of heavy metals and their binary mixtures on hippocampal HT-22 cell line." Toxicology letters 282 (October 5, 2017): 25–36. https://doi.org/10.1016/j.toxlet.2017.10.002.

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Humans are exposed to a cocktail of heavy metal toxicants in the environment. Though heavy metals are deleterious, there is a paucity of information on the toxicity of mixtures. In this study, four common neurotoxicity heavy metals lead (Pb) cadmium (Cd), arsenic (As), and methylmercury (MeHg) were exposed individually and as mixtures to HT-22 cell line for 8days. The study established that low dose exposures induced toxicity to the HT-22 cell line during 8days. The results indicates potency dependent response, the toxicity of single metals on the HT-22 cells; MeHg > As > Cd > Pb. The

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Sandberg, Maxwell, Wyatt Whitman, Christina Ross, Matvey Tsivian, and Stephen Walker. "Pulsed electromagnetic field therapy's effect on bladder cancer cell line HT-1376." Journal of Clinical Oncology 42, no. 4_suppl (2024): 666. http://dx.doi.org/10.1200/jco.2024.42.4_suppl.666.

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666 Background: Pulsed electromagnetic field therapy (PEMF) is a magnetic waveform energy that can be targeted for delivery to cells and/or patients. It is noninvasive, and to date no reported negative side effects exist. Recently, its use as a therapeutic for cancer has come into focus. However, to our knowledge, no study has examined the effect of PEMF on bladder cancer at the cellular level. In this study, we sought to examine how PEMF altered a bladder cancer cell line (HT-1376) at the genomic level. Methods: HT-1376 cells were cultured, and cells were plated into either a control plate (n

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Soylu, Sinan. "Crocus Officinalis (L.) Extract on Human Colerectal Cancer Cell Line (HT-22): Investigation in Vitro." Cumhuriyet Science Journal 45, no. 1 (2024): 35–39. http://dx.doi.org/10.17776/csj.1419826.

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Crocus sativus L. has been used as spice, food colouring and medicinal plant for thousands of years. In this study, antioxidant properties and cytotoxic effect of saffron extract were evaluated in HT-22 cell lines. Malignant and non-malignant cells (L929) were cultured in DMEM medium and incubated with different concentrations of saffron extract in different solvents (water, ethanol, ethyl-acetate, n-hexane). Cell viability was determined by MTT assay. Antioxidant parameters such as DPPH, FRAP, total polyphenol and flavonoid amounts were measured. The highest DPPH value was found as 15.90±0.12

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Karri, Venkatanaidu, Marta Schuhmacher, Vikas Kumar, David Ramos, and Eliandre De Oliveira Cacheado. "Proteomics approach for improving the mechanisms associated with MeHg toxicity in HT-22 hippocampal cell line." Toxicology Letters 280 (October 2017): S259. http://dx.doi.org/10.1016/j.toxlet.2017.07.920.

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Ji, Yang‐Fei, Dan Wang, Yan‐Ru Liu, Xing‐Rong Ma, Hong Lu, and Bo‐Ai Zhang. "MicroRNA‐132 attenuates LPS‐induced inflammatory injury by targeting TRAF6 in neuronal cell line HT‐22." Journal of Cellular Biochemistry 119, no. 7 (2018): 5528–37. http://dx.doi.org/10.1002/jcb.26720.

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Illmer, Christoph, Sibylle Madlener, Zsuzsanna Horvath, et al. "Immunologic and Biochemical Effects of the Fermented Wheat Germ Extract Avemar." Experimental Biology and Medicine 230, no. 2 (2005): 144–49. http://dx.doi.org/10.1177/153537020523000209.

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Avemar (MSC) is a nontoxic fermented wheat germ extract demonstrated to have antitumor effects. Avemar has the potential to significantly improve the survival rate in patients suffering from malignant colon tumors. We studied its effects in the HT-29 human colon carcinoma cell line. Avemar had an inhibiting effect on colonies of HT-29 cells with an IC50 value of 118 μg/ml (7 days of incubation); this value could be decreased to 100 and 75 μg/ml in the presence of vitamin C. In the cell line examined, Avemar induced both necrosis and apoptosis, as demonstrated by Hoechst/propldium iodide staini

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Rae, Julie, Jason Hackney, Kevin Huang, Mary Keir, and Ann Herman. "Identification of an IL-22-Dependent Gene Signature as a Pharmacodynamic Biomarker." International Journal of Molecular Sciences 22, no. 15 (2021): 8205. http://dx.doi.org/10.3390/ijms22158205.

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Interleukin-22 (IL-22) plays a role in epithelial barrier function and repair, and may provide benefits in conditions like inflammatory bowel disease. However, limited human data are available to assess the clinical effect of IL-22 administration. This study used a human intestinal cell line to identify an IL-22-dependent gene signature that could serve as a pharmacodynamic biomarker for IL-22 therapy. The response to IL-22Fc (UTTR1147A, an Fc-stabilized version of IL-22) was assessed in HT-29 cells by microarray, and the selected responsive genes were confirmed by qPCR. HT-29 cells demonstrat

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Betul, Danısman, and Cicek Betul. "Agomelatine protects hippocampal neurons against doxorubicin induced toxicity." GSC Biological and Pharmaceutical Sciences 24, no. 2 (2023): 290–96. https://doi.org/10.5281/zenodo.10440942.

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Doxorubicin (DOX) is a powerful chemotherapy drug used in numerous cancer treatments, known to causes neurotoxicity and impair cognitive function in cancer patients. The main mechanism thought to be responsible for the neuronal damage related to chemotherapy is oxidative stress. Agomelatine (AGM) has recently been identified as a neuroprotective agent against toxicity and the effect of AGM on DOX-induced neurotoxicity was investigated in this study. In order to evaluate the effect of AGM on oxidative stress and apoptosis, malondialdehyde (MDA), lactate dehydrogenase (LDH), superoxide dismutase

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Більше джерел

Дисертації з теми "HT-22 cell line"

Karri, Venkatanaidu. "Integrated In vitro - Omics based Approach to assess the Heavy metals and their Binary mixtures toxicity in Hippocampal HT-22 cell line." Doctoral thesis, Universitat Rovira i Virgili, 2018. http://hdl.handle.net/10803/553243.

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Els estudis toxicol'ogics d'avui dia fan l'avaluació d'exposicions i riscos en el cervell sense abordar adequadament les possibles interaccions de metalls en la regió del cervell de l'hipocamp. Es va avaluar la neurotoxicitat similar / disímil de cada metall en el cervell que pot donar un fort suport a l'efecte de mescles en el cervell (Capítol 1). L'abast del nostre estudi és provar el metall únic (Pb, Cd, As i MeHg) i les seves mescles d'impacte tòxic crònic en la línia cel·lular hipocamp HT-22 mitjançant l'ús de la metodologia de biologia in vitro i del sistema. Inicialment, es van rea

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