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Статті в журналах з теми "In vitro anti fungal activity-assay"

Автор: Grafiati

Опубліковано: 3 червня 2025

Оновлено: 31 липня 2025

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1

Moharram, A. M., A. A. Zohri, H. M. Omar, and El-Ghani O. A. Abd. "In vitro assessment of antimicrobial and anti-inflammatory potential of endophytic fungal metabolites extracts." European Journal of Biological Research 7, no. 3 (2017): 234–44. https://doi.org/10.5281/zenodo.839696.

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Endophytes are endosymbiotic microorganisms that act as reservoir of novel bioactive secondary metabolites with antimicrobial, cytotoxic and anti-cancer activities. In the present study, the extracts of 26 different endophytic fungal strains were screened for their antimicrobial and anti-inflammatory activities. The results showed a wide variety of antimicrobial activities against 12 target microorganisms including three Gram (+) bacteria, three Gram (-) bacteria, 3 yeasts, 2 dermatophytic fungi and one keratinophilic fungus. Four fungal extracts (<em>Aspergillus versicolor</em>,<em> A. awamor

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2

Novriyanti, Eka, Erdy Santosa, Wasrin Syafii, Maman Turjaman, and Sitepu Irnayuli R. "ANTI FUNGAL ACTIVITY OF WOOD EXTRACT OF Aquilaria crassna Pierre ex Lecomte AGAINST AGARWOOD-INDUCING FUNGI, Fusarium solani." JOURNAL OF FORESTRY RESEARCH 7, no. 2 (2010): 155–65. https://doi.org/10.20886/ijfr.2010.7.2.155-165.

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This paper provided information regarding artificial agar wood production. Fungi are considered as biological agent for agarwood formation and agarwood is assumed as tree defense mechanism product. This research was aimed at investigating the anti fungal activity (AFA) of <em>Aq</em><em>ui</em><em>l</em><em>ari</em><em>a crassna</em>, one of the agar wood-producing trees, against <em>F</em><em>usariu</em><em>m solani in vi</em><em>t</em><em>r</em><em>o</em>. <em>Aq</em><em>uilaria crassna </em>wood mill was extracted by 70% ethanol to investigate the anti fungal activity. The result are <em>Aq

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3

Priya B and Vijayachitra A. "Anti-atherosclerotic and Anti-Biofilm properties of Pleurotus ostreatus Metabolites." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 5533–38. http://dx.doi.org/10.26452/ijrps.v11i4.3187.

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To investigate the anti-biofilm and anti-atherosclerotic properties of metabolites from a mushroom, Pleurotus ostreatus was selected as the main objective of present study. The study involved the following series of steps to meet the objective. Coating the metal stents with fungal metabolites and vitamin-E, to study the anti-biofilm properties against biofilm producing bacterial species (Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Staphylococcus epidermidis and Pseudomonas aeruginosa), to determine the drug release behaviour from the coated stents, and to investigate the cy

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4

Sinha, Durgeshnandani, Trilochan Satapathy, Parag Jain, et al. "In Vitro Antidiabetic Effect of Neohesperidin." Journal of Drug Delivery and Therapeutics 9, no. 6 (2019): 102–9. http://dx.doi.org/10.22270/jddt.v9i6.3633.

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Objective: The present study was performed to determine in vitro antidiabetic effect of neohesperidin. To evaluate inhibitory effect of neohesperidin on α-amylase and α-glucosidase diabetes causing enzyme. Methods and Materials: Invitro carbohydrate metabolizing enzyme based inhibitory methods were used to determine antidiabetic effect of neohesperidin. Alpha (α)-amylase inhibitory assay was performed using different sources i.e. wheat alpha (α)-amylase enzyme, salivary alpha (α)-amylase and fungal alpha (α)-amylase assay. Alpha (α)-glucosidase inhibitory assay was performed using alpha

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5

Aji, Oktira Roka, and Yuni Rohmawati. "Antifungal activity of Morinda citrifolia leaf extracts against Fusarium oxysporum." Indonesian Journal of Biotechnology and Biodiversity 4, no. 1 (2020): 20–26. http://dx.doi.org/10.47007/ijobb.v4i1.51.

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Fusarium oxysporum is an important disease that causes wilt disease in plants. Fungal pathogen control using synthetic fungicides can cause negative impacts on the environment. Morinda citrifolia is one of the herbs that is known for many benefits. M. citrifolia leaf contains anthraquinone which have potential as antifungal agents. In this study, in vitro anti-fungal assay was conducted against F. oxysporum to analyze the antifungal activity of ethanol extract of M. citrifolia leaves. In vitro evaluation was carried out using poisoned food technique at four different concentrations i.e., 20%,

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6

Saranya, J., S. Preethi, Mohammed Rafi Shaik, Merajuddin Khan, Mujeeb Khan, and Baji Shaik. "Development of Cerium Oxide/Chitosan/Graphene Oxide Nanocomposite: An Investigation toward Its Biological Applications under In Vitro Conditions." Crystals 13, no. 9 (2023): 1393. http://dx.doi.org/10.3390/cryst13091393.

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A ternary nanocomposite was prepared using cerium oxide, chitosan, and graphene oxide (CeO2/CS/GO) using a simple and cost-effective wet chemical method. The physicochemical properties of the developed ternary nanocomposite were examined using X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy with energy-dispersive X-ray spectroscopy, and ultraviolet-visible spectroscopy. Furthermore, the therapeutic behavior of the developed CeO2/CS/GO composite was assessed using anti-bacterial, anti-fungal, and anti-cancer assays. For Escherichia coli, Staphylococcus a

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7

Ranjitha, Dhevi V. Sundar, and Arunachalam Sathiavelu. "Anti-Multidrug resistant activity of endophytic fungi isolated from the stem of Tradescantia pallida against Gram-positive pathogens." Research Journal of Biotechnology 18, no. 6 (2023): 24–28. http://dx.doi.org/10.25303/1806rjbt024028.

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The present study aimed at the isolation and in vitro anti-MRSA and antioxidant properties of endophytic fungi derived from the stem of Tradescantia pallida. The fungal endophytes were isolated in a PDA agar medium. A total of seven isolates were recovered. Sequential solvent extraction was done using different polarity solvents and the crude extracts obtained were tested for their antagonistic activity against drug-resistant bacteria. In vitro, the antioxidant activity of the potent fungus was carried out by DPPH assay. Crude extract from TPS2 isolate displayed maximum inhibition towards Meth

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8

Sugashini, Settu, and Arunachalam Sathiavelu. "In Vitro anti-diabetic and antioxidant potential of endophytic fungi isolated from Bryophyllum pinnatum L." Research Journal of Biotechnology 18, no. 4 (2023): 9–18. http://dx.doi.org/10.25303/1804rjbt09018.

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Diabetes is a chronic metabolic disease and one of the leading causes of death compared to all health issues. Diabetes drugs can be used to regulate the activity of metabolic enzymes including amylase in diabetic patients. Endophytes are a group of microorganisms that reside in the internal tissue of all higher plants without causing any of the symptoms they live in. Endophytic fungi isolated from plants can serve as a reservoir of secondary metabolites since they can prevent diabetes through alpha-amylase activity. Current research has isolated endophytic fungi from the leaves of Bryophyllum

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9

Takey, Irfanul Islam, Hasib Khan Shomudro, and Sadia Afreen Chowdhury. "Evaluation of In-vitro Anti-Inflammatory, Anti-Fungal, Thrombolytic, Membrane Stabilizing and Cytotoxic Properties of (Camellia chrysantha Hu Tuyama)." Asian Journal of Medicine and Health 22, no. 7 (2024): 36–44. http://dx.doi.org/10.9734/ajmah/2024/v22i71043.

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The current study was set out to look into the anti-inflammatory, anti-fungal, cytotoxic, thrombolytic and membrane stabilizing activities of the methanolic extract from the leaf of Camellia chrysantha (Hu) Tuyama (MECCL). Primary evaluation of MECCL was performed via phytochemical screening. Phytochemical analysis of the leaf extract revealed the presence of reducing sugar, flavonoids, alkaloids, and steroids. Anti-inflammatory activity test was done using egg albumin denaturation assay. In the result of MECCL’s anti-inflammatory test showed 88.88% compared to the standard acetyl salicylic ac

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10

Vankudothu, Narendar, R. Chandrashekhar, N. Lakshmi Bhavani, Sudhakar Chekuri, and S. Y. Anwar. "In-vitro evaluation of Anti-bacterial and Anti-fungal activity of different Explant extracts of Thespesia populnea L." International Journal of Research and Development in Pharmacy & Life Sciences 6, no. 7 (2017): 2874–80. http://dx.doi.org/10.21276/ijrdpl.2278-0238.2017.6(7).2874-2880.

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11

Dogra, Shivani, Bhupendra Koul, Joginder Singh, Meerambika Mishra, and Dhananjay Yadav. "Phytochemical Analysis, Antimicrobial Screening and In Vitro Pharmacological Activity of Artemisia vestita Leaf Extract." Molecules 29, no. 8 (2024): 1829. http://dx.doi.org/10.3390/molecules29081829.

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Artemisia vestita Wall. Ex Besser is a folklore medicinal plant that belongs to Asteraceae family and a treasure trove of drugs. The aim of this research study was to investigate the phytoconstituents, antimicrobial activity, antioxidant, anti-inflammatory, cytotoxicity and wound healing potential of A. vestita leaf extract (ALE). Phytochemical analysis of the ALE was carried out by Soxhlet extraction and GCMS (gas chromatography–mass spectrometry) analysis. Antimicrobial activity was performed by the agar well diffusion method against selected bacterial and fungal strains. Free radical scaven

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12

Manipal, Sunayana, Fazlia Shireen, and D. Prabu. "Anti-fungal activity of Aloe vera: In vitro stud." SRM Journal of Research in Dental Sciences 6, no. 2 (2015): 92. http://dx.doi.org/10.4103/0976-433x.155464.

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13

M., Nilofer Noorie, and Chenthamarai G. "Anti-fungal activity of Carica papaya leaf extract against candida albicans and its synergy with fluconazole: an in-vitro study." International Journal of Basic & Clinical Pharmacology 10, no. 1 (2020): 101. http://dx.doi.org/10.18203/2319-2003.ijbcp20205547.

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Background: In this study objectives were to evaluate the antifungal activity in increasing concentrations of ethanolic extract and aqueous extract of Carica papaya against Candida albicans and to assess the synergistic activity of ethanolic extract of Caricia papaya with flucanazole as a potential antifungal.Methods: The aim of the study was to evaluate the antifungal activity in increasing concentrations, 500 µl/ml, 750 µl/ml and 1000 µl/ml of ethanolic extract and aqueous extract of caricia papaya against Candida albicans and the synergistic activity with Fluconazole was assessed by observi

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14

Abbas, Ali, Syed Ali Raza Naqvi, Muhammad Hidayat Rasool, Asma Noureen, Muhammad Samee Mubarik, and Rasool Baksh Tareen. "Phytochemical Analysis, Antioxidant and Antimicrobial Screening of Seriphidium Oliverianum Plant Extracts." Dose-Response 19, no. 1 (2021): 155932582110047. http://dx.doi.org/10.1177/15593258211004739.

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The aim of this study was to investigate the phytochemicals using reverse-phase high pressure liquid chromatography (RP-HPLC), antioxidant, antifungal and antibacterial activities of Seriphidium oliverianum stem extracts. The extraction was carried out by conventional shaking process (CSP) and ultrasonic assisted process (UAP). The highest total phenolic contents (97.85 ± 0.735 mg gallic acid equivalent (GAE)/g sample) and flavonoid contents (188.15 ± 0.53 mg catechin equivalent (CE)/g sample) were found in methanol extract obtained by CSP. Antioxidant activity was investigated using DPPH° sca

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15

Krishnen, Ranjeni, and Sreedharan Muniandy. "Fungicidal Effectiveness of Super-Oxidized Solution In Vitro: Potential Implications for Wound Care." Wounds: a compendium of clinical research and practice 35, no. 8 (2023): e243-e247. http://dx.doi.org/10.25270/wnds/23017.

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Introduction. Drug-resistant fungal infections in chronic wounds represent a major clinical challenge to clinicians. Fungal infections delay wound healing by prolonging inflammation and encouraging biofilm formation, which protects microbes against host defenses and anti-infective medications. As such, interventions that prevent and control nosocomial fungal infections without interfering with the wound healing process are increasingly required. Although conventional antiseptics can effectively exert fungicidal effects, they also have adverse effects on human cells. SOS is a well-known bacteri

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16

Thamilvanan, D., A. Ram kumar, R. Ramesh, B. S. Balakumar, and S. Kumaresan. "IN VITRO ANTI-BACTERIAL ACTIVITY OF THE SOIL FUNGAL METABOLITES." International Research Journal Of Pharmacy 9, no. 11 (2018): 175–81. http://dx.doi.org/10.7897/2230-8407.0911279.

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17

de Souza Santos, Marcela, Willian Jonis Andrioli, Maria Perpétua Freire de Morais Del Lama, Jairo Kenupp Bastos, N. P. Dhammika Nanayakkara, and Rose Mary Zumstein Georgetto Naal. "In vitro anti-allergic activity of the fungal metabolite pyridovericin." International Immunopharmacology 15, no. 3 (2013): 532–38. http://dx.doi.org/10.1016/j.intimp.2013.01.017.

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18

Chhillar, Anil Kumar. "In Vitro Analysis of Benzopyran Derivative's Action Against Aspergillus Species." Journal of Lifestyle and SDGs Review 5, no. 1 (2024): e02801. http://dx.doi.org/10.47172/2965-730x.sdgsreview.v5.n01.pe02801.

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Objective: The objective of this study is to investigate in vitro activity of two specific benzopyran derivatives: Ethyl 2-(4-oxo-4H-chromen-3-yl)-4,5-dihydrothiazole-4-carboxylate and 2-(4-oxo-4H-chromen-3-yl) thiazolidine., with the aim of ascertaining their minimum inhibitory concentration (MIC) and discerning their cytotoxic effects on human RBCs. Theoretical Framework: Aspergillus fumigatus causes numerous global deaths annually. Its increasing resistance to conventional antifungals and many azoles underscores the urgency for new therapeutic solutions. Method: Compounds were synthesized a

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19

Parveen, Romana, Tooba Naz Shamsi, Himanshu Kumar, and Sadaf Fatima. "PHYTOCHEMICAL ANALYSIS AND IN VITRO BIOLOGICAL CHARACTERIZATION OF AQUEOUS AND METHANOLIC EXTRACT OF BACOPA MONNIERI." International Journal of Pharmacy and Pharmaceutical Sciences 8, no. 12 (2016): 90. http://dx.doi.org/10.22159/ijpps.2016v8i12.14739.

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<p><strong>Objective</strong>:<strong> </strong>The present study was designed to identify the phytocompounds, to compare the antibacterial, antioxidant, and anti-inflammatory effects of aqueous and methanolic extract of <em>Bacopa monnieri</em>.</p><p><strong>Methods</strong>:<strong> </strong>Antioxidant activity was determined by 1, 1-diphenyl-2-picrylhydrazyl (DPPH), Ferric Reducing Antioxidant Power (FRAP), Super oxide dismutase (SOD), Reduced glutathione (GSH), Catalase assays. Anti-inflammatory activity was me

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20

Aruna, K., and K. Rosaiah. "Curbing the growth of candida-A comparative in-vitro study." PJSR 4, no. 1 (2011): 12–14. https://doi.org/10.5281/zenodo.8274247.

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Endodontics is the least forgiving branch of dentistry in terms of success or failure. Therefore, re-treatment has become a significant part of today’s endodontic practice. There is a growing evidence showing the presence of fungi especially Candida albicans in root canals of obturated teeth in which endodontic treatment has failed. It has been demonstrated that Candida species are resistant to some medications used in endodontics. The aim of this study was to examine the invitro susceptibility of Candida albicans to materials used in endodontics such as mineral trioxide aggregate (MTA),

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21

Borcea, Anca-Maria, Gabriel Marc, Ioana Ionuț, et al. "A Novel Series of Acylhydrazones as Potential Anti-Candida Agents: Design, Synthesis, Biological Evaluation and In Silico Studies." Molecules 24, no. 1 (2019): 184. http://dx.doi.org/10.3390/molecules24010184.

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In the context of an increased incidence of invasive fungal diseases, there is an imperative need of new antifungal drugs with improved activity and safety profiles. A novel series of acylhydrazones bearing a 1,4-phenylene-bisthiazole scaffold was designed based on an analysis of structures known to possess anti-Candida activity obtained from a literature review. Nine final compounds were synthesized and evaluated in vitro for their inhibitory activity against various strains of Candida spp. The anti-Candida activity assay revealed that some of the new compounds are as active as fluconazole ag

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22

Bomfim de Barros, Daniela, Luanna de Oliveira e Lima, Larissa Alves da Silva та ін. "α-Pinene: Docking Study, Cytotoxicity, Mechanism of Action, and Anti-Biofilm Effect against Candida albicans". Antibiotics 12, № 3 (2023): 480. http://dx.doi.org/10.3390/antibiotics12030480.

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Candida albicans is associated with serious infections in immunocompromised patients. Terpenes are natural-product derivatives, widely studied as antifungal alternatives. In a previous study reported by our group, the antifungal activity of α-pinene against C. albicans was verified; α-pinene presented an MIC between 128–512 µg/mL. In this study, we evaluate time-kill, a mechanism of action using in silico and in vitro tests, anti-biofilm activity against the Candida albicans, and toxicity against human cells (HaCaT). Results from the molecular-docking simulation demonstrated that thymidylate s

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23

Dwibedi, Vagish, and Sanjai Saxena. "In Vitro Anti-oxidant, Anti-fungal and Anti-staphylococcal Activity of Resveratrol-Producing Endophytic Fungi." Proceedings of the National Academy of Sciences, India Section B: Biological Sciences 90, no. 1 (2019): 207–19. http://dx.doi.org/10.1007/s40011-019-01098-6.

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24

Osamudiamen, Paul M., Bamidele Durodola, Fisayo T. Osamudiamen, Davies O. Nwude, and Olapeju O. Aiyelaagbe. "Preliminarily investigation on the In-vitro Antimicrobial, Antioxidant and Antidiabetic Activities of Sorindeia warneckei Extracts." Annals of Science and Technology 8, no. 2 (2023): 79–85. http://dx.doi.org/10.2478/ast-2023-0018.

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Abstract Phytochemicals that are naturally occurring in plants are known to be potentially bioactive, having anti-oxidative, antimicrobial and enzyme inhibiting potentials. This study investigated the antimicrobial, antioxidant and antidiabetic activities of the methanol and dichloromethane extracts of the leaf and stem Sorindeia warneckei. The plant extract showed the presence of saponins, flavonoids, terpenoids, tannins, glycosides, coumarins, steroids, alkaloids, anthraquinones and reducing sugars. The antioxidant potential was evaluated using DPPH radical scavenging assay while the antidia

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25

Jain, Neeru, Ashutosh Sharma, A. K. Srivastava, and Mayank Bansal. "Evaluation of Antifungal Potential of Syzygium cumini Ethosomal Gel." Journal of Biomedical and Pharmaceutical Research 14, no. 3 (2025): 32–37. https://doi.org/10.32553/jbpr.v14i3.1318.

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The present study focuses on the development of a gel formulation incorporating leaf extract of Syzygium cumini L. and its evaluation for in-vitro anti-fungal activity. Syzygium cumini L. (Skeels), a widely cultivated medicinal plant, is known for its diverse pharmacological properties. In this investigation, ethosomal formulations of S. cumini extract were prepared and incorporated into a gel base. The anti-fungal efficacy of the formulation was assessed against Aspergillus flavus and Aspergillus niger using the agar well diffusion method. The results revealed a concentration-dependent increa

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26

Javed, Muhammad Salman, Muhammad Zubair, Komal Rizwan, and Muhammad Jamil. "In Vitro Anti-Microbial Activity and Anti-Cancer Potential of Novel Synthesized Carbamothioyl-Furan-2-Carboxamide Derivatives." Molecules 28, no. 12 (2023): 4583. http://dx.doi.org/10.3390/molecules28124583.

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A series of carbamothioyl-furan-2-carboxamide derivatives were synthesized using a one-pot strategy. Compounds were obtained in moderate to excellent yields (56–85%). Synthesized derivatives were evaluated for their anti-cancer (HepG2, Huh-7, and MCF-7 human cancer cell lines) and anti-microbial potential. Compound p-tolylcarbamothioyl)furan-2-carboxamide showed the highest anti-cancer activity at a concentration of 20 μg/mL against hepatocellular carcinoma, with a cell viability of 33.29%. All compounds showed significant anti-cancer activity against HepG2, Huh-7, and MCF-7, while indazole an

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27

Prakash, Ved, Kiran Rajendra Giri, Kamlesh M. Palandurkar, Tuhina Banerjee, and Pue Rakshit. "Preliminary evaluation of in-Vivo and in-Vitro antifungal activity of Piper longum, Origanum majorana, Embelia ribes and Butea monosperma with Gas chromatography-mass spectrometry analysis of phytochemical property of plant extracts against Candida species causing dermatological." IP Indian Journal of Clinical and Experimental Dermatology 10, no. 1 (2024): 11–18. http://dx.doi.org/10.18231/j.ijced.2024.002.

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Анотація:

: Globally, fungi infections cause more than 1.5 million fatalities annually, mostly in those with weakened immune systems with Candida albicans found to be the chief pathogen. Approximately one to two billion people are affected by dermatological fungal infections involving skin and skin appendages, perhaps very difficult to estimate its exact prevalence due to under-reporting, this augments the requirements for more attention towards new molecules to combat resistance.: Evaluation of antifungal activity of Piper longum, Origanum majorana, Embelia ribes, Butea monosperma both in-vivo and in-v

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28

Giftson, Paul, Jerrine Joseph, Revathy Kalyanasundaram, V. Ramesh Kumar, and Wilson Aruni. "In vitro evaluation of the anti-mycobacterial properties of the extracts of Momordica Charantia." Research Journal of Biotechnology 16, no. 7 (2021): 15–22. http://dx.doi.org/10.25303/167rjbt1521.

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Tuberculosis (TB) is a communicable disease and remains one of the top 10 causes of death worldwide. One fourth of the world population is infected with TB at a risk of developing disease. The increase in the incidence of drug resistant TB around the world urges the need to develop a new candidate to fight against the disease. Plants were considered as the rich source of bioactive components to be used as potential drugs. Medicinal plants are used in pure as well as crude materials for their medicinal properties. Our research aims in identifying the phyto-molecules which have anti- tuberculosi

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29

Pinky, Sagorika Sing, Sirajum Monira, Md Akbar Hossain, and Amir Hossain. "Antioxidant, Anti-inflammatory, Cytotoxic and Analgesic Activities of Sensevieria trifasciata." Bangladesh Pharmaceutical Journal 23, no. 2 (2020): 195–200. http://dx.doi.org/10.3329/bpj.v23i2.48341.

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Sansevieria trifasciata is a common perennial ornamental plant which freely grows and widely found in homes, parks, and woodlands. Traditionally, this plant has been used against acne, allergy, helminths and fungal infections. In the present study, the ethanolic extract of leaves of Sansevieria trifasciata (STET) has been used to study the phytoconstituents and several bioactivities. In vitro antioxidant activity of STET has been determined by DPPH scavenging assay and measuring the total tannins and phenolic contents. Anti-inflammatory activity has been evaluated by hypotonic solution and hea

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30

Manohar Babu, S., V. Harish, D. Sivanaga Reddy, K. Jowhar Ali, and N. Srinavya. "ANTI OXIDANT, MICROBIAL AND PHYTO CHEMICAL STUDIES OF CARICA PAPAYA MILK: A NATURAL HAND SANITIZER." International Journal of Advanced Research 10, no. 02 (2022): 1062–66. http://dx.doi.org/10.21474/ijar01/14313.

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In this study, the effect of Carica papayaagainst various microorganisms is evaluated using DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) assay for antioxidant activity. The focus is on employing the antimicrobial and antioxidant activities of papaya milk as a natural antimicrobial by preparing hand sanitizer.Papaya (Carica papaya Linn), a nutraceutical fruit well known for its nutritional values and potent medicinal properties such as antioxidant, anti-bacterial, anti-helminthic, anti-fungal, anti-hypertensive and anti-fertility, free radical scavenging activity [1-10]. The study includesextr

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31

Shaari, Fatin Nabila, and Nur Ain Izzati Mohd Zainudin. "In Vitro and in Vivo Assays of Selected Plant Extracts Against Fruit Rot Fungi." Sains Malaysiana 52, no. 9 (2023): 2545–57. http://dx.doi.org/10.17576/jsm-2023-5209-06.

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Post-harvest losses of crops in Malaysia is estimated at around 20%. Fungal infection is one of the primary causes of post-harvest loss in fruits. The common use of synthetic fungicide to combat fruit rot fungi poses negative impacts on human health and the environment. The objective of this study was to determine the efficacy of selected plant species as a safer alternative for post-harvest treatment. Ethanolic leaf extracts of Piper sarmentosum, Psidium guajava, and Cymbopogon citratus were tested against Fusarium oxysporum from tomato rot, Fusarium proliferatum from banana rot, and Colletot

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Paw, Manabi, Roktim Gogoi, Neelav Sarma, et al. "Study of Anti-oxidant, Anti-inflammatory, Genotoxicity, and Antimicrobial Activities and Analysis of Different Constituents found in Rhizome Essential Oil of Curcuma caesia Roxb., Collected from North East India." Current Pharmaceutical Biotechnology 21, no. 5 (2020): 403–13. http://dx.doi.org/10.2174/1389201020666191118121609.

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Background: This investigation was designed to evaluate the chemical composition, antioxidant, anti-inflammatory, genotoxicity, and antimicrobial activities of Curcuma caesia Roxb rhizome essential oil. Methods: Gas Chromatography/Mass Spectroscopy (GC/MS) analysis was performed to determine the chemical composition, standard antioxidative test DPPH assay, reducing power assay, in vitro antiinflammatory activity (egg albumin denaturation, protease inhibitory assay) by using standard methods. Similarly, antimicrobial activity was tested using the disc diffusion method, minimum inhibitory concen

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He, Jie, Monica A. Thomas, Emma Van Why, Mitchell H. Grayson, Brian F. Volkman, and Anna R. Huppler. "Chemokine CCL28 treats oropharyngeal candidiasis through rapid membrane disruption." Journal of Immunology 204, no. 1_Supplement (2020): 59.1. http://dx.doi.org/10.4049/jimmunol.204.supp.59.1.

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Abstract Candida albicans is a commensal organism that causes life-threatening or life-altering opportunistic infections. Treatment of these infections is limited by the paucity of anti-fungal drug classes. Antimicrobial peptides are a component of the immune response to fungi and promising agents for drug development. CCL28 is a CC chemokine that is abundant in saliva and has in vitro antimicrobial activity. In this study, we examine the spectrum of in vitro antimicrobial activity and the in vivo Candida killing capacity of CCL28 in oropharyngeal candidiasis (OPC), as well as the mechanism of

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K.K., Sivakumar, Rajalakshmi G, and Rajasekaran A. "Synthesis, characterization and biological evaluation of Schiff bases of 5-amino-4-[2-(4-nitro-1,3-benzothiazol-2 yl)hydrazinylidene]-2,4-dihydro- 3H-pyrazol-3-one derivatives." International Journal of Drug Design and Discovery 3, no. 4 (2025): 886–97. https://doi.org/10.37285/ijddd.3.4.2.

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In the present work totally 12 Schiff bases of 5-amino-4-[2-(4-nitro-1,3-benzothiazol-2 yl)hydrazinylidene]-2,4-dihydro- 3H-pyrazol-3-one were synthesized. Synthesized compounds were characterized on the basis of physicochemical as well as spectral data (UV, IR, 1HNMR and mass spectra) and evaluated for in vitro anti-microbial, anti-tubercular and cytotoxic activity. All the synthesized compounds (100 Âµg/disc) showed mild to moderate activity against Gram-positive bacteria, more potent or equal activity against Gram-negative bacteria and moderate to significant anti-fungal activity compared w

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Andrea, Mariano*1 Angelo Salzo1 &. Daniela Prioriello2. "REVISITING A SOUTHERN ITALIAN TRADITIONAL PRACTICE: IN VITRO ANTIFUNGAL ACTIVITY ASSAY BY SOME PLANT EXTRACTS AGAINST CANDIDA ALBICANS. PRELIMINARY DATA REPORT." International Journal of Medical Research and Pharmaceutical Sciences 6, no. 1 (2019): 30–35. https://doi.org/10.5281/zenodo.2551767.

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<em>Candida</em> species represent the most common cause of fungal infections worldwide. In this study, we have evaluated the antifungal activity of plant aqueous extracts against a standard strain of <em>Candida albicans</em>, to assess a widespread practice in their allegedly healing use in southern Italian tradition. The tested plants were: pomegranate (<em>Punica granatum</em>), rue (<em>Ruta graveolens</em>), walnut (<em>Juglans regia</em>), tomato (<em>Solanum lycopersicum</em>), garlic (<em>Allium sativum</em>). Results showed a potential antifungal and anti biofilm-forming activity in

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Karthikeyan, G., Maneesh Paul-Satyaseela, Nachiappan Dhatchana Moorthy, Radha Gopalaswamy, and Shridhar Narayanan. "Functional characterization of Candida albicans Hos2 histone deacetylase." F1000Research 2 (May 23, 2014): 238. http://dx.doi.org/10.12688/f1000research.2-238.v2.

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Candida albicans is a mucosal commensal organism capable of causing superficial (oral and vaginal thrush) infections in immune normal hosts, but is a major pathogen causing systemic and mucosal infections in immunocompromised individuals. Azoles have been very effective anti-fungal agents and the mainstay in treating opportunistic mold and yeast infections. Azole resistant strains have emerged compromising the utility of this class of drugs. It has been shown that azole resistance can be reversed by the co-administration of a histone deacetylase (HDAC) inhibitor, suggesting that resistance is

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Ajmal, Muhammad Saqib, and Ifrah Rashid. "In vitro management of the early blight of tomato by various chemical Fungicides and plant products." Phytopathogenomics and Disease Control. 1, no. 1 (2023): 1–6. http://dx.doi.org/10.22194/pdc/2.102.

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Pathogens reduce crop yield and quality, making their control necessary. In vitro studies examined the effects of botanicals (marigold, kikar, and ginger) and fungicides (Antracol, Captan, and Dithane M 45) against Alternaria solani. Botanicals (marigold, kikkar and ginger), fungicides (Antracol, Captan, and Dithane M 45), concentrations of botanicals (50%, 75% and 100%) and concentrations of fungicides (250 ppm, 500 ppm, and 1000 ppm) were the factors studied to effect the inhibition of A. solani. Mycelial growth diameter, inhibition, and spore germination were measured. Botanicals displayed

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Bhagyasri, Y., NVinay reddy, M. Dattatrya, K. Divya, and NSiva Subramanian. "PHYTOCHEMICAL SCREENING AND IN-VITRO ANTI-FUNGAL ACTIVITY OF “TRIDAX PROCUMBENS L." International Journal of Advanced Research 5, no. 7 (2017): 2131–37. http://dx.doi.org/10.21474/ijar01/4952.

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Rode, Milind, Sahebrao Rindhe, and Bhausaheb Karale. "Synthesis and biological activities of some indoline derivatives." Journal of the Serbian Chemical Society 74, no. 12 (2009): 1377–87. http://dx.doi.org/10.2298/jsc0912377r.

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The reaction of indoline with a substituted benzoyl chloride in the presence of K2CO3 in THF gave compound 4. Compound 4 was subjected to chlorosulphonation to obtain compound 5. Condensation of aromatic amines with compound 5 led to the synthesis of indoline derivatives 6(a-f). Similarly, 5-nitroindoline was treated with a substituted benzoyl chloride to obtain the nitro compound 9, which was reduced using stannous chloride and reacted further with aromatic sulphonyl chloride to obtain the indoline derivatives 11(a-e). These compounds were tested for antibacterial, anti-tuberculosis and antif

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40

Prerana Sahu, Madhur Soni, Divyansh Sahu, Tanuj Pandey, Gyanesh Kumar Sahu, and Harish Sharma. "Pharnaceutical Formulation And In Vitro Evaluation of An Herbal Anti – Fungal Cream." International Journal of Latest Technology in Engineering Management & Applied Science 14, no. 5 (2025): 174–81. https://doi.org/10.51583/ijltemas.2025.140500021.

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Abstract: The rising incidence of fungal infections has highlighted the urgent need for treatments that are both effective and safe. Herbal antifungal creams have gained attention as a viable alternative to synthetic products due to their natural composition, reduced side effects, and eco-friendly nature. This research is cantered on the formulation and evaluation of a topical herbal antifungal cream that utilizes plant-derived active ingredients known for their antifungal efficacy. Specifically, neem, aloe vera, and clove oil were chosen for their well-documented activity against fungal patho

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Binorkar, Sandeep, Gajanan Parlikar, Ranjeet Sawant, Manish Bhoyar, and Milind B. Nikumbh. "In-Vitro Trial of Roots of Ishwarmuli (Aristolochia indica Linn.) for Anti-Microbial, Anti-Fungal & Anti-Oxidant Activity." International Journal of Ayurvedic Medicine 11, no. 3 (2020): 405–9. http://dx.doi.org/10.47552/ijam.v11i3.1637.

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Aristolochia indica is a plant belonging to the family Aristolochiaceae. The medicinal value of A. indica has been known in different system of traditional medicine including Ayurveda. A number of Aristolochia species has been used in herbal medicines throughout the world for the cure of several ailments including metabolic diseases to venomous bites of snake and insects. The current work was executed with an objective to explore the in vitro antimicrobial, anti-fungal and anti-oxidant activity of A. indica. The relevant literature was also pursued for the justification and comparing the resem

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Sharma, G., and R. Sharma. "Novel spiro[indoline-3,2′thiazolo[5,4-e]pyrimido[1,2-a] pyrimidine] derivatives as possible anti-dermatophytic and anti-candidiasis agent." Biomeditsinskaya Khimiya 70, no. 3 (2024): 180–86. http://dx.doi.org/10.18097/pbmc20247003180.

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A novel series of 5′-benzylidene-3′-phenylspiro[indoline-3,2′-thiazolidine]-2,4′(1H)-diones 6a-d and spiro[indoline-3,2′-thiazolo[5,4-e]pyrimido[1,2-a]pyrimidin]-2(1H)-one 9a-d derivatives have been synthesized. All the newly synthesized compounds were evaluated for antifungal and anti-candidiasis activity by using Disc Diffusion and Modified Microdilution methods. The antimicrobial experiments have shown that the synthesized compounds demonstrated broad-spectrum antifungal activity in vitro. Among them, compounds 9a-9d had stronger antifungal activity against Trichophyton rubrum, Trichophyton

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Alzahrani, Badr, Abozer Y. Elderdery, Abdullah Alsrhani, et al. "Effects of Albumin–Chlorogenic Acid Nanoparticles on Apoptosis and PI3K/Akt/mTOR Pathway Inhibitory Activity in MDA-MB-435s Cells." Nanomaterials 13, no. 9 (2023): 1438. http://dx.doi.org/10.3390/nano13091438.

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In this study, we synthesized, characterized, and explored the anti-microbial and anti-cancer effects of albumin–chlorogenic acid nanoparticles (NPs). Characterization studies with a UV-vis spectrophotometer, FTIR, PL spectrum, TEM, FESEM, XRD, and DLA analysis showed patterns confirming the physio–chemical nature of biogenic nanocomposites. Further, anti-microbial studies using bacterial strains Staphylococcus aureus, Streptococcus pneumonia, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Vibrio cholera, and fungal strain Candida albicans showed significant (p < 0.05) anti-ba

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Barua, Aruna, Md Ruhul Kuddus, M. Mohi Uddin Chowdhury, Mohammad A. Rashid, and Mohammed Ibrahim. "Antioxidant, Anti-inflammatory, Antimicrobial and Thrombolytic Activities of Eclipta alba L. Growing in Bangladesh." Bangladesh Pharmaceutical Journal 26, no. 1 (2023): 20–27. http://dx.doi.org/10.3329/bpj.v26i1.64214.

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Eclipta alba L. (Family: Asteraceae) is an evergreen herb of ethnomedicinal significance in the Indian subcontinent. The present study was carried out to determine the in vitro antioxidant, anti-inflammatory, antimicrobial and thrombolytic activities of n-hexane, chloroform and aqueous soluble fractions of ethanol crude extract of E. alba whole plant. Preliminary phytochemical screening was performed by qualitative tests which revealed the presence of alkaloids, steroids, glycosides, tannins, flavonoids, saponins and amides in E. alba. During the DPPH (2,2-diphenyl-1-picrylhydrazyl) scavenging

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Shehensha, Sheik, and Jyothi M. Vijaya. "In vitro Antifungal Activity of Psidium Guajava Based Silver Nanoparticles." Journal of Pure and Applied Microbiology 14, no. 3 (2020): 2075–83. http://dx.doi.org/10.22207/jpam.14.3.48.

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To prepare and characterize silver nanoparticles from Guava leaves (Psidium guajava), extracts (chloroform and ethanol). The fabricated silver nanoparticles were tested on resistant fungal strains, Aspergillus niger and Candida glabrata. Psidium guajava leaf extracts were obtained by cold maceration method, by using Chloroform and Ethanol. To one mL of extract 2mM silver nitrate solution was added. The mixture was kept overnight in a dark chamber at room temperature. The solution was centrifuged at 10,000 rpm for 15 minutes and filtered by wattman filter paper after centrifugation. Psidium gua

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Shah, Muddaser, Waheed Murad, Najeeb Ur Rehman, et al. "Biomedical Applications of Scutellaria edelbergii Rech. f.: In Vitro and In Vivo Approach." Molecules 26, no. 12 (2021): 3740. http://dx.doi.org/10.3390/molecules26123740.

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In the current study, in vitro antimicrobial and antioxidant activities and in vivo anti-inflammatory and analgesic activities of Scutellaria edelbergii Rech. f. (crude extract and subfractions, i.e., n-hexane, ethyl acetate (EtOAc), chloroform, n-butanol (n-BuOH) and aqueous) were explored. Initially, extraction and fractionation of the selected medicinal plant were carried out, followed by phytochemical qualitative tests, which were mostly positive for all the extracts. EtOAc fraction possessed a significant amount of phenolic (79.2 ± 0.30 mg GAE/g) and flavonoid (84.0 ± 0.39 mg QE/g) conten

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Abu-Izneid, Tareq, Abdur Rauf, Saud Bawazeer, Abdul Wadood та Seema Patel. "Anti-Dengue, Cytotoxicity, Antifungal, and In Silico Study of the Newly Synthesized 3-O-Phospo-α-D-Glucopyranuronic Acid Compound". BioMed Research International 2018 (3 грудня 2018): 1–5. http://dx.doi.org/10.1155/2018/8648956.

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The aim of the current study was to synthesize new bioactive compounds and evaluate their therapeutic relevance. The chemical structure of compound 7 (methyl 3-O-phospo-α-D-glucopyranuronic acid was elucidated by physical and advance spectral technique. Also, this compound was assessed for various in vitro biological screening. The results showed that compound 7 has promising antifungal activity against selected fungal strains. Computational study was also carried out to find antimalarial efficacy of the synthesized compounds. Compounds (2-7) were tested for cytotoxicity by MTT assay, and no c

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Binorkar, Sandeep V., Gajanan R. Parlikar, Rashtrapal N. Ukey, and Rajendra Nirgude. "IN VITRO EVALUATION OF BILVADI AGADA (HERBO-MINERAL COMPOUND) FOR ANTI-MICROBIAL AND ANTI-FUNGAL ACTIVITY." Journal of Biological & Scientific Opinion 1, no. 2 (2013): 59–64. http://dx.doi.org/10.7897/2321-6328.01205.

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Fadillah, Wendi Nurul, Nampiah Sukarno, Dyah Iswantini, Min Rahminiwati, Novriyandi Hanif, and Mashuri Waite. "In Vitro Pancreatic Lipase Inhibition by Marine Fungi Purpureocillium lilacinum Associated with Stylissa sp. Sponge as Anti-obesity Agent." HAYATI Journal of Biosciences 29, no. 1 (2021): 76–86. http://dx.doi.org/10.4308/hjb.29.1.76-86.

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This study aimed to evaluate the potential of marine fungus Purpureocillium lilacinum isolated from an Indonesian marine sponge Stylissa sp. as an anti-obesity agent through pancreatic lipase inhibition assay. The fungus was identified as P. lilacinum through morphological and molecular characteristics. The fungal extract’s inhibition activity and kinetics were evaluated using spectrophotometry and Lineweaver-Burk plots. Ethyl acetate and butanol were used for extraction. Both extracts showed pancreatic lipase inhibition in a concentration-dependent manner. Both crude extracts were then fracti

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Priya, Rajendran Lakshmi, Bheeranna Kariyanna, Sengodan Karthi, Raja Sudhakaran, Sundaram Ganesh Babu, and Radhakrishnan Vidya. "Facile Synthesis and Characterization of Cupric Oxide Loaded 2D Structure Graphitic Carbon Nitride (g-C3N4) Nanocomposite: In Vitro Anti-Bacterial and Fungal Interaction Studies." Journal of Fungi 9, no. 3 (2023): 310. http://dx.doi.org/10.3390/jof9030310.

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The active and inexpensive catalyst cupric oxide (CuO) loaded foliar fertilizer of graphitic carbon nitride (g-C3N4) is investigated for biological applications due to its low cost and easy synthesis. The synthesized CuO NPs, bulk g-C3N4, exfoliated g-C3N4, and different weight percentages of 30 wt%, 40 wt%, 50 wt%, 60 wt%, and 70 wt% CuO-loaded g-C3N4 are characterized using different analytical techniques, including powder X-ray diffraction, scanning electron microscopy, energy dispersive X-ray analysis, and ultraviolet-visible spectroscopy. The nanocomposite of CuO NPs loaded g-C3N4 exhibit

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