Добірка наукової літератури з теми "Insulin-like growth factor-binding proteins"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Оберіть тип джерела:
Ознайомтеся зі списками актуальних статей, книг, дисертацій, тез та інших наукових джерел на тему "Insulin-like growth factor-binding proteins".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
За допомогою хмари тегів ви можете побачити ще більше пов’язаних тем досліджень, а відповідні кнопки після кожного розділу сторінки дозволяють переглянути розширені списки книг, статей тощо на обрану тему.
Статті в журналах з теми "Insulin-like growth factor-binding proteins":
Kostecká, Z., and J. Blahovec. "Animal insulin-like growth factor binding proteins and their biological functions." Veterinární Medicína 47, No. 2 - 3 (March 30, 2012): 75–84. http://dx.doi.org/10.17221/5807-vetmed.
Lee, Chang Hoon, Chin Saeng Cho, Kyung-You Park, Joon Woo Kim, Gwan Won Lee, Byung Kwon Lee, and Jae Soo Lee. "The Role of Insulin-Like Growth Factor I and Binding Protein in Cholesteatoma Fibroblasts." Journal of Clinical Otolaryngology Head and Neck Surgery 14, no. 1 (May 2003): 113–17. http://dx.doi.org/10.35420/jcohns.2003.14.1.113.
Purwana, Arie, Budiono Budiono, Jose RL Batubara, and Muhammad Faizi. "Association of Growth Velocity with Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Children with a Vegan Diet." Journal of Biomedicine and Translational Research 6, no. 1 (February 6, 2020): 6–10. http://dx.doi.org/10.14710/jbtr.v6i1.5474.
Leroith, Derek. "Insulin-like growth factor receptors and binding proteins." Baillière's Clinical Endocrinology and Metabolism 10, no. 1 (January 1996): 49–73. http://dx.doi.org/10.1016/s0950-351x(96)80298-9.
Coverley, J. A., and R. C. Baxter. "Phosphorylation of insulin-like growth factor binding proteins." Molecular and Cellular Endocrinology 128, no. 1-2 (April 1997): 1–5. http://dx.doi.org/10.1016/s0303-7207(97)04032-x.
Collet, Chris, and Judith Candy. "How many insulin-like growth factor binding proteins?" Molecular and Cellular Endocrinology 139, no. 1-2 (April 1998): 1–6. http://dx.doi.org/10.1016/s0303-7207(98)00078-1.
Bach, Leon A. "Insulin-like growth factor binding proteins 4-6." Best Practice & Research Clinical Endocrinology & Metabolism 29, no. 5 (October 2015): 713–22. http://dx.doi.org/10.1016/j.beem.2015.06.002.
Baxter, Robert C. "Insulin-like growth factor binding proteins as glucoregulators." Metabolism 44 (October 1995): 12–17. http://dx.doi.org/10.1016/0026-0495(95)90215-5.
Ferry Jr., Robert J., Ruben W. Cerri, and Pinchas Cohen. "Insulin-Like Growth Factor Binding Proteins: New Proteins, New Functions." Hormone Research in Paediatrics 51, no. 2 (1999): 53–67. http://dx.doi.org/10.1159/000023315.
Feld, Stella M., and Raimund Hirschberg. "Insulin-like growth factor-I and insulin-like growth factor-binding proteins in the nephrotic syndrome." Pediatric Nephrology 10, no. 3 (May 1, 1996): 355–58. http://dx.doi.org/10.1007/s004670050124.
Дисертації з теми "Insulin-like growth factor-binding proteins":
Robertson, James Gray. "Insulin-like growth factors and insulin-like growth factor binding proteins in wounds /." Title page, contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phr6509.pdf.
Hopkins, Nicholas John. "Insulin-like growth factor-I and its binding proteins." Thesis, University of Reading, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240702.
Clark, Sarah Jane. "The growth hormone, insulin-like growth factor, insulin-like growth factor binding proteins and insulin axis in acute liver failure." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397943.
Jones, Tiffany Celeste. "Syndecan-4 binds insulin-like growth factor binding protein-4." Birmingham, Ala. : University of Alabama at Birmingham, 2009. https://www.mhsl.uab.edu/dt/2010r/jones.pdf.
Mireuta, Matei. "Aspects of insulin-like growth factor binding proteins in cancer." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114128.
L'ensemble du système de facteurs de croissance insulinomimétique (IGF) est composé de deux ligands (IGF-1 et IGF-2), de deux récepteurs (IGF- 1R et IGF-2R) et de six protéines de liaison (IGFBP-1 à 6). Les IGFs sont des hormones endocrines, paracrines et autocrines qui stimulent la croissance cellulaire, la prolifération et le métabolisme. Il existe un grand nombre d'études utilisant des approches épidémiologiques ou des modèles in vivo et in vitro qui démontrent l'importance des IGFs dans le contexte du cancer. Le IGF-1R est le récepteur physiologique des deux ligands et son activation mène à d'importants changements cellulaires tels que l'activation des voies de signalisation PI3K/AKT/mTOR et Ras/Raf/MAPK. Étant donné son rôle dans la promotion et dans la progression du cancer, le système des IGFs représente une cible potentielle pour le traitement du cancer. De façon classique, les protéines de liaison IGFBP ont été décrites comme de simples porteurs d'IGFs dans le sang et autres fluides. Les IGFBPs peuvent modifier la biodisponibilité des IGFs de façon positive en augmentant leur demi-vie ou de façon négative due à leur compétition avec le IGF-1R pour la liaison. En plus de leur rôle classique, il est de plus en plus évident que ces protéines peuvent agir de manière indépendante, mais les mécanismes impliqués restent flous. Également, il existe des études épidémiologiques qui ont corrélé la surexpression de IGFBPs, en particulier IGFBP-2, avec un pronostic défavorable dans plusieurs formes de cancer. Bien que le rôle des IGFBPs ait été largement étudié dans le contexte de la croissance normale et en néoplasie, la présente thèse révèle quelques nouveaux aspects de la physiologie des IGFBPs dans le contexte du cancer. En première partie, nous étudions l'effet de la voie de signalisation PI3K/AKT/mTOR sur l'expression du gène IGFBP-2 dans une lignée cellulaire de cancer du sein. Nous démontrons que l'activation de cette voie mène essentiellement à une augmentation de la transcription de ce gène de manière dépendante au facteur de transcription Sp-1. De plus, nous établissons que Sp-1 est phosphorylé par l'activation de la voie PI3K/AKT/mTOR et s'accumule dans le noyau. En deuxième partie, nous étudions les effets de la molécule 2-deoxyglucose (2-DG) sur la liaison entre IGF-1 et IGFBP-3. Un récent article avait suggéré un effet inhibitoire de cette molécule sur la formation de complexes IGF -1 :IGFBP-3. Nous démontrons par trois méthodes différentes que 2-DG ou la molécule apparentée glucose n'ont aucun effet sur la liaison entre IGF-1 et IGFBP-3. De plus, nous démontrons que les effets cellulaires de 2-DG sur l'activation de la voie PI3K/AKT/mTOR observées par les auteurs de l'article en question ne sont pas universels et sont probablement le résultat de signaux intracellulaires. Finalement, en dernière partie, nous étudions les effets d'un nouvel anticorps thérapeutique nommé BI836845 qui possède une grande affinité pour IGF-1 et IGF-2. Dans des échantillons de sérum de souris ex vivo, nous démontrons que l'ajout de BI836845 déplace IGF-1 des complexes naturels contenant les IGFBPs vers des complexes contenant l'anticorps. In vivo, nous démontrons que BI836845 lie la grande majorité d'IGF-1. Nous démontrons aussi que l'anticorps mène à une baisse de la concentration de IGFBP-3 et à une hausse de la concentration de l'hormone de croissance chez des souris C57 BL/6.
Twigg, Stephen Morris. "Insulin-like growth factor binding protein-5 and its complexes." Thesis, The University of Sydney, 1998. https://hdl.handle.net/2123/27686.
Milner, Steven John. "The oxidative folding of insulin-like growth factor-I analogues /." Title page, table of contents and summary only, 1996. http://web4.library.adelaide.edu.au/theses/09PH/09phm65945.pdf.
Nickerson, Tara. "A role for insulin-like growth factor binding proteins in apoptosis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0022/NQ50229.pdf.
Lucic, Melinda Robin. "Characterisation of the molecular interactions between insulin-like growth factors and their binding proteins." Title page, contents and abstract only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phl9375.pdf.
de, los Rios Patricia. "Insulin-like growth factor binding proteins (IGFBPs) in ovine fetal growth plate chondrocytes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0011/MQ28557.pdf.
Книги з теми "Insulin-like growth factor-binding proteins":
Colloque médecine et recherche (8th : 2008 Paris, France). IGFs: Local repair and survival factors throughout life span. Heidelberg: Springer, 2010.
Jr, Roberts Charles T., and Rosenfeld Ron G, eds. The IGF system: Molecular biology, physiology, and clinical applications. Totowa, N.J: Humana Press, 1999.
1945-, LeRoith Derek, ed. Insulin-like growth factors: Molecular and cellular aspects. Boca Raton: CRC Press, 1991.
Alcuin Symposium (2000 Aachen, Germany). Insulin & related proteins: Structure to function and pharmacology. Dordrecht: Kluwer Academic Publishers, 2002.
Westwood, Melissa. Biochemical characterisation of insulin-like growth factor binding protein-1. Manchester: University of Manchester, 1994.
White, Darren Andrew. An analytical study of insulin-like growth factor binding proteins in human serum. Birmingham: University of Birmingham, 1995.
1945-, LeRoith Derek, Raizada Mohan K, and International Symposium on Insulin, IGFs, and their Receptors (4th : 1993 : Woods Hole, Mass.), eds. Current directions in insulin-like growth factor research. New York: Plenum, 1993.
LeRoith, Derek. Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics. Boston, MA: Springer Science+Business Media, LLC, 2012.
Lawlor, Margaret Ann. The role of the insulin-like growth factor-II/mannose-6-phosphate receptor in embryonic development. Dublin: University College Dublin, 1998.
Mapoko, Ilondo Mbelenge. Cellular receptors for human growth hormone: Quantitative aspects and clinical applications. Leuven: Leuven University Press, 1988.
Частини книг з теми "Insulin-like growth factor-binding proteins":
Holly, Jeff M. P., and Janet K. Fernihough. "The Insulin-Like Growth Factor (IGF) Binding Proteins (IGFBPS)." In Growth Hormone, 77–96. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-5163-8_5.
Baxter, R. C. "Insulin-like Growth Factor Binding Proteins: Biochemical Characterization." In Growth Hormone and Somatomedins during Lifespan, 100–108. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78217-6_9.
Clemmons, D. R. "Role of Insulin-like Growth Factor Binding Proteins in Modulating Insulin-like Growth Factor Action." In Growth Hormone and Somatomedins during Lifespan, 109–16. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78217-6_10.
Seth, John. "Insulin-Like Growth Factor Binding Protein-1." In The Immunoassay Kit Directory, 206. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-1414-1_31.
Seth, John. "Insulin-Like Growth Factor Binding Protein-3." In The Immunoassay Kit Directory, 207–9. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-1414-1_32.
Bidlingmaier, M. "Insulin-like growth factor binding protein-3." In Lexikon der Medizinischen Laboratoriumsdiagnostik, 1–2. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_1585-1.
Bidlingmaier, M. "Insulin-like growth factor binding protein-3." In Springer Reference Medizin, 1257–58. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_1585.
Wilczak, Nadine, and Jacques de Keyser. "Insulin-Like Growth Factor System in Amyotrophic Lateral Sclerosis." In IGF-I and IGF Binding Proteins, 160–69. Basel: KARGER, 2005. http://dx.doi.org/10.1159/000085764.
Minniti, Giuseppe, and Youngman Oh. "Insulin-Like Growth Factor Binding Proteins in Endocrine-Related Neoplasia." In Endocrine Oncology, 215–35. Totowa, NJ: Humana Press, 2000. http://dx.doi.org/10.1007/978-1-59259-223-4_11.
Ocrant, Ian. "Insulin-Like Growth Factor Binding Proteins in the Nervous System." In Advances in Experimental Medicine and Biology, 471–82. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5949-4_42.
Тези доповідей конференцій з теми "Insulin-like growth factor-binding proteins":
Bruns, Alexander-Francisco, Jessica Smith, Pooja Shah, Nadira Yuldasheva, Mark T. Kearney, and Stephen Wheatcroft. "145 Insulin-like growth factor binding protein 2 (igfbp2) positively regulates angiogenesis." In British Cardiovascular Society Annual Conference ‘High Performing Teams’, 4–6 June 2018, Manchester, UK. BMJ Publishing Group Ltd and British Cardiovascular Society, 2018. http://dx.doi.org/10.1136/heartjnl-2018-bcs.141.
Rice, Megan S., Rulla M. Tamimi, James L. Connolly, Laura C. Collins, Dejun Shen, Michael N. Pollak, Bernard Rosner, Susan E. Hankinson, and Shelley S. Tworoger. "Abstract A68: Insulin-like growth factor-1, insulin-like growth factor binding protein-3, and lobule type in the Nurses' Health Study II." In Abstracts: AACR International Conference on Frontiers in Cancer Prevention Research‐‐ Oct 22-25, 2011; Boston, MA. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1940-6207.prev-11-a68.
Park, Jae-Hyun, Morten Grønbech Rasch, Jing Qiu, Ida Katrine Lund, Zena Werb, and Mikala Egeblad. "Abstract 2465: Matrix metalloproteinase 9 promotes breast cancer through regulation of insulin-like growth factor-binding proteins." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-2465.
Silvers, Amy L., Lin Lin, David G. Beer, and Andrew C. Chang. "Abstract 830: Insulin-like growth factor binding protein-2 and chemosensitivity in esophageal adenocarcinoma." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-830.
Dar, Altaf A. "Abstract 5004: Functional modulation of insulin-like growth factor binding protein-3 in melanoma." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-5004.
Contois, Liangru W., Jennifer M. Caron, Eric Tweedie, Leonard Liebes, Robert Friesel, Calvin Vary, and Peter C. Brooks. "Abstract 3485: Insulin-like growth factor binding protein-4 (IGFBP-4) differentially inhibits growth factor induced angiogenesis in vivo." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3485.
Angeles, Christina V., Markus Hafner, Nicholas D. Socci, Penelope DeCarolis, Thomas Tuschl, and Samuel Singer. "Abstract 3100: The RNA-binding protein insulin-like growth factor 2 mRNA-binding protein 3 is oncogenic in liposarcoma." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3100.
Aditya Prayudi, Pande Kadek, I. Nyoman Gede Budiana, and Ketut Suwiyoga. "54 Diagnostic accuracy of serum insulin-like growth factor binding protein 2 for ovarian cancer." In ESGO SoA 2020 Conference Abstracts. BMJ Publishing Group Ltd, 2020. http://dx.doi.org/10.1136/ijgc-2020-esgo.97.
Ibrahim, YH, J. Hartel, K. La Parra, and D. Yee. "Insulin-like growth factor binding protein-1 (IGFBP-1) targets both the insulin-like growth factor (IGF) and integrin pathways for the inhibition of breast cancer cell motility." In CTRC-AACR San Antonio Breast Cancer Symposium: 2008 Abstracts. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-402.
Ahasic, Amy M., Rihong Zhai, Li Su, Konstantinos Aronis, Christos S. Mantzoros, B. T. Thompson, and David C. Christiani. "IGFBP3 Polymorphism Is Associated With Plasma Insulin-Like Growth Factor (IGF)-1 And Insulin-Like Growth Factor Binding Protein (IGFBP-3) In An Intensive Care Unit (ICU) Cohort." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3545.
Звіти організацій з теми "Insulin-like growth factor-binding proteins":
Gross, Jennifer M. Insulin-Like Growth Factor Binding Protein-1 Interacts with Integrins to Inhibit Insulin-Like Growth Factor-Induced Breast Cancer Growth and Migration. Fort Belvoir, VA: Defense Technical Information Center, July 2003. http://dx.doi.org/10.21236/ada420347.
Harbeson, Caroline E., and Steven A. Rosenzweig. The Role of Insulin-Like Growth Factor (IGF) Binding Proteins (IGFBPs) in IGF-Mediated Tumorigenicity. Fort Belvoir, VA: Defense Technical Information Center, July 2003. http://dx.doi.org/10.21236/ada420331.
Harbeson, Caroline E., and Steven A. Rosenzweig. The Role of the Insulin-Like Growth Factor (IGF) Binding Proteins (IGFBPs) in IGF-Mediated Tumorigenicity. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada409808.
Rosenfeld, Ron G. A Novel Member of the Insulin-Like Growth Factor Binding Protein Superfamily in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, February 2004. http://dx.doi.org/10.21236/ada438221.
Rosenfeld, Ron G. A Novel Member of the Insulin-Like Growth Factor Binding Protein Superfamily in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, February 2001. http://dx.doi.org/10.21236/ada393860.
Rosenfeld, Ron G. A Novel Member of the Insulin-Like Growth Factor Binding Protein Superfamily in Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, February 2002. http://dx.doi.org/10.21236/ada406049.
Schoen, Timothy J. Expression and Characterization of Insulin-Like Growth Factor Binding Proteins (IGFBPs) and IGFBP-2 mRNA in the Developing Chicken Eye. Fort Belvoir, VA: Defense Technical Information Center, March 1995. http://dx.doi.org/10.21236/ad1011459.
Dodd, Janice G. In Vivo Activity of Insulin-Like Growth Factor Binding Protein-3 in Prevention of Prostate Cancer Progression. Fort Belvoir, VA: Defense Technical Information Center, October 2008. http://dx.doi.org/10.21236/ada519976.
Erickson, Keesha E., Oleksii S. Rukhlenko, Md Shahinuzzaman, Kalina P. Slavkova, Yen Ting Lin, Edward C. Stites, Marian Anghel, et al. Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor. Office of Scientific and Technical Information (OSTI), September 2018. http://dx.doi.org/10.2172/1473773.
Funkenstein, Bruria, and Shaojun (Jim) Du. Interactions Between the GH-IGF axis and Myostatin in Regulating Muscle Growth in Sparus aurata. United States Department of Agriculture, March 2009. http://dx.doi.org/10.32747/2009.7696530.bard.
You might want to see the page in this language: English.